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2. Efficacy and safety of sparsentan versus irbesartan in patients with IgA nephropathy (PROTECT): 2-year results from a randomised, active-controlled, phase 3 trial

Author

Abbasciano, Isabella, Abrantes, Catarina, Accarino, Simone, Adler, Sharon, Adoberg, Annika, Afsari, Rouzbeh, Ahmad, Syeda, Ahmed, Jafar, Ahn, Wooin, Ajayi, Bamidele, Aksamit, Dariusz, Al Chalabi, Saif, Alamartine, Eric, Alchi, Bassam, Ali, Mohammad, Aliotta, Roberta, Almaani, Salem, Almeida, Catarina, Almeida, Edgar, Alvarez, Francisco de la Prada, Alves, Patricia, Annese, Francesca, Appel, Gerald, Arduan, Alberto Ortiz, Arena, Maria, Arevalo, Marta Calvo, Arfaania, Dariush, Arias, Carlos, Aristoy, Emma Calatayud, Asakiene, Egle, Ashley, Sarah, Assefi, Ali, Atenza, Alba, Auerbach, Asta, Augustyniak-Bartosik, Hanna, Avella, Monroy, Ayling-Smith, Jonathan, Ayoub, Isabelle, Ayvazyan, Christine, Baccaro, Rocco, Bailey, Asha, Baker, Bruce, Balamuthusamy, Saravanan, Ballarin, Jose, Barata, Rui, Barbic, Jerko, Barisic, Dunja, Barratt, Jonathan, Barreto, Jose Carlos de Jesus, Barrios, Clara, Belingheri, Mirco, Benesova, Anna, Bernabeu, Ana Avila, Bernhardt, Wanja, Bhadra, Shamik, Biancone, Luigi, Blanchard, Anne, Boaglio, Elena, Bolignano, Davide, Bomback, Andrew, Bonilla, Gustavo Andres Useche, Bordoli, Monica, Bose, Bhadran, Boudville, Neil, Brandon, Donald, Brown, Karen, Broyet, Christian, Bucknall, Thomas, Buffet, Alexandre, Bumblyte', Inga Arune, Burdese, Manuel, Burgos, Natalia Allende, Burguet, Laure, Burtey, Stephane, Busch, Martin, Cakiroglu, Figen, Campbell, Victoria, Canetta, Pietro, Capaccio, Flavia, Carbonell, Juan, Cardoso, Filipa, Carro, Clara Garcia, Carroll, Robert, Carron, Pierre-Louis, Carullo, Nazareno, Cassia, Matthias, Caster, Dawn, Castillo, Belen Vizcaino, Catucci, Davide, Cavalli, Andrea, Chae, Dong-Wan, Chakera, Aron, Chan, Doris, Chan, Gary Chi Wang, Chan, Anthony Ting Pong, Chan, Lai Wan, Chang, Jae Hyun, Chang, Ming-Shan, Chapman, Fiona, Charytan, Chaim, Chaudhry, Asghar, Cheetham, Melissa, Chen, Cheng-Hsu, Chen, Hsin-Yu, Chen, Chien-Liang, Chen, Hung-Yuan, Chen, Hung-Chun, Chenine, Leila, Cheung, Siu Fai, Cheung, Chee Kay, Chiche-Jourde, Noemie, Chiu, Hsien-Fu, Chiu, Yen-Ling, Chiu, Yi-Wen, Chiu, Ian, Choi, Hoon Young, Chou, Kang-Ju, Chowdhury, Paramit, Chowdhury, Pradip, Chrysochou, Constantina, Chukwu, Chukwuma, Chun, Ka Yeong, Chung, Wookyung, Cieniawski, Dominik, Claisse, Guillaume, Clayton, Philip, Cleary, Catalina Martín, Clement, Nisha, Coates, Toby, Cogno, Chiara, Colla, Loredana, Collins, Michael, Colucci, Marco, Combe, Christian, Comi, Nicolino, Comunale, Roderick, Contreras, Gabriel, Cooper, Bruce, Coppock, Gaia, Costa, Ana Cortesão, Costanzi, Stefano, Cozzolino, Mario, Crail, Susan, Cunha, Liliana, Curry, Elizabeth, Dai, Tiane, Daina, Erica, Daneshvari, Sam, Dasgupta, Indranil, DaSilva, Louise, Davidson, Robert, De Bhailis, Aine Maire, de Précigout, Valérie, Decupere, Marc, Delmas, Yahsou, Deodato, Francesca, Dhaun, Neeraj, Dhaygude, Ajay, Dhelaria, Ranjit, Di Maio, Federica, Diezhandino, Maria Angeles Goicoechea, Dika, Zivka, Dinic, Miriana, Dittmer, Ian, Dobre, Mirela, Doctor, Gabriel, Donati, Gabriele, Doubel, Peter, Douthit, Nicole, Draganova, Diliana, Drexler, Yelena, Drinkovic, Martin, Drinovska, Klara, Dudreuilh, Caroline, Dumond, Clement, Durlen, Ivan, Dussol, Bertrand, Encarnacion, Montserrat Diaz, Endre, Zoltan, Enrique, Jorge, Eqbal, Yusuf, Erlich, Jonathan, Esposito, Vittoria, Esposito, Ciro, Fakih, Faisal, Fang, Hua-Chang, Farinha, Ana, Fearday, Aaron, Felgueiras, Joana de Sousa Soares, Felicjanczuk, Elzbieta, Fernandes, João Carlos, Fernandes, Sara, Fernandes, Adriana, Fernandez, Jose Luño, Fernandez, Victor, Fernando, Mangalee, Figueiredo, Ana Carolina, Firre, Eric, Floege, Jürgen, Flossmann, Oliver, Floyd, Lauren, Fonseca, Nuno, Fonseca, Jose Nuno de Almeida Agapito, Foote, Celine, Forbes, Suzanne, Forcen, Angel, Fornoni, Alessia, Fouassier, David, Fraser, Ian, Fung, Ka Shun Samuel, Furlano, Monica, Furtado, Teresa, Gadh, Rajdeep, Gaisset, Roxane, Gallagher, Martin, Gameiro, Joana, Gangadharan, Muralikrishna, Garcia, Fabiola Alonso, Garcia, Olga Gracia, Garg, Gunjan, Garrouste, Cyril, Gautam, Archana, Geara, Abdallah, Geddes, Colin, Gellineo, Lana, Germain, Michael, Gesualdo, Loreto, Ghalli, Farid, Giaroni, Francesco, Giles, Harold, Gillies, Alastair, Gimeno, Ana Vilar, Girardet, Annette, Glaze, Jeffrey, Goh, Tze, Gois, Mario, Goldsmith, Christopher, Goma, Elena, Gomes, Ana Marta, Goncalves, Luis Pedro Falcao, Goncalves, Sara, Gontarek-Kacprzak, Julita, Gonzalez, Carlos, Gopu, Arun, Gowda, Nayan, Gray, Nicholas, Greco, Barbara, Green, Heather, Greze, Clarisse, Griffin, Sian, Guldris, Secundino Cigarran, Guzman, Ursula Verdalles, Ha, Jeffrey Tsun Kit, Hall, Amanda, Hamilton, Patrick, Han, Seung Hyeok, Haws, Robert, Hayat, Ashik, Heath, Lauren, Heinrichs, Sven, Henderson, Andrew, Henderson, Amy, Hendren, Elizabeth, Heng, Anne-Elisabeth, Heres, Salia Virxinia Pol, Herfurth, Johann Konstantin, Herrero, Evangelina Merida, Ho, Tzung-Yo, Hogan, Jonathan, Hohenstein, Bernd, Hollett, Peter, Horvatic, Ivica, Hsu, Bang-Gee, Hsu, Chia-Tien, Hsu, Chih-Yang, Hsu, Shih-Ping, Huang, Chien-Wei, Hudson, Amy, Hung, Chi-Chih, Hwang, Shang-Jyh, Hwang, Daw-Yang, Hyun, Young Youl, Ilmoja, Madis, Irish, Georgina, Jacob, Radu, Jahan, Sadia, Jain, Arunima, Jamar, Sofie, Jander, Anna, Jang, Hye Ryoun, Janko, Catherine, Jardine, Meg, Jaskowski, Piotr, Jeantet, Guillaume, Jelakovic, Bojan, Jeon, Junseok, Jeong, Jong Cheol, Jesudason, Shilpanjali, Jittirat, Arksarapuk, Jo, Sang-Kyung, Jones, Rachel, Joo, Narae, Jorge, Sofia, Julian, Bruce, Jung, JiYong, Jyothinagaram, Praveena, Kadakia, Jigar, Kamal, Fahameedah, Kanigicherla, Durga, Karanovic, Sandra, Karras, Alexandre, Kasimatis, Theodoros, Kassem, Mohamad, Kattamanchi, Siddhartha, Keller, Christopher, Kentric, Dubravka Trajbar, Kettner, Christiane, Khalil, Kassem, Kim, Dana, Kim, Se Joong, Kim, Yeong Hoon, Kim, Yunmi, Kim, Hyung Wook, Kim, Sunggyun, Kim, Jwa-Kyung, Kim, Aejin, Kim, Myung-Gyu, Kimber, Cassandra, Klamm, Kathryn, Koch, Annegret, Koester, Eric, Kolvald, Kulli, Kon, Sui, Kooienga, Laura Ann, Kotwal, Sradha, Krajewska, Magdalena, Kratka, Karolina, Krishnan, Anoushka, Krishnasamy, Rathika, Krueger, Thilo, Kruljac, Ivan, Kulka, Simone, Kunzendorf, Ulrich, Kuo, Mei-Chuan, Kuo, Hung-Tien, Kuo, Sheng, Kwan, Lorraine Pui Yuen, Kwella, Norbert, Kwella, Bogna, Kyaw, Kay, Labat, Aurore, Lafayette, Richard, Lagatta, Mark, Lam, Chi Kwan Darwin, Lambie, Mark, Lanaret, Camille, Latif, Farah, Laute, Margo, Law, Wai Ping, Lawman, Sarah, Lazo, Mercedes Salgueira, Lee, Hajeong, Lee, Moon Hyoung, Lee, Kyu-Beck, Lee, Hyung-seok, Lee, JungEun, Lee, Hyun Hee, Lee, Po-Tsang, Leis, Liisi, Lemahieu, Wim, Leung, Janson, Li, Yan, Lie, Davina Ngoi Wah, Lifland, Howard, Lilienthal, Kadri, Lim, Wai, Limardo, Monica, Livrozet, Marine, Longhi, Selena, Lopes, Daniela, Lopes, Jose Antonio, Lorde, Nathan, Luxton, Grant, Ma, Mingyao, Madhrira, Machaiah, Madonia, Phillip, Maes, Bart, Mahadevan, Kumaradevan, Mahdi, Amar, Mahdi, Eamon, Maillard, Nicolas, Maixnerova, Dita, Majstorovic Barac, Karolina, Malecki, Robert, Malfait, Thomas, Malvica, Silvia, Mandayam, Sreedhar, Manley, Paul, Mansfield, Nick, Marcantoni, Carmelita, Mariat, Christophe, Marin, Tamara Malek, Marin, Lida Maria Rodas, Mark, Patrick, Marques, Joana, Martinez, Eduardo Gutierrez, Martinez, Stacy, Masset, Catherine, Masson, Ingrid, Mather, Amanda, Maung Myint, Thida Maung, Mayet, Valentin, McCafferty, Kieran, McCarthy, Ellen, McDonald, Stephen, McGreal, Kerri, McMahon, Kellyn, McNally, Andrew, McQuarrie, Emily, Medina, Allyson, Meeus, Gert, Mehta, Kshama, Mendoza, Elder, Menezes, Maria, Meng, Jerry, Messa, Piergiorgio, Messias, Ana, Miarka, Przemyslaw, Miglinas, Marius, Mikacic, Ivana, Mikhail, Ashraf, Milicevic, Martina, Minasian, Raffi, Moeller, Marcus, Mohey, Hesham, Mojarrab, Javad, Mok, Maggie Ming Yee, Moncasi, Eduardo Parra, Moonen, Martial, Morales, Wenceslao Adrian Aguilera, Moreno, Eduardo Verde, Moreno, Antolina, Morris, Adam, Moutzouris, Dimitrios, Moya, Mercedes Gonzalez, Mucha, Simon, Musolino, Michela, Napodano, Pietro, Natario, Ana, Negrea, Lavinia, Nelson, Bradley, Neuen, Brendon, Newsome, Britt, Ng, Kit Chung Jack, Nguyen, Thu, Nguyen, Viet, Nicolo, Clementine, Nitschke, Martin, Noble, Euan, Nolasco, Fernando, O'Lone, Emma, Ochoa, Adriana Sierra, Oh, Kook-Hwan, Oh, SeWon, Okoh, Pedro, Ombelet, Sara, O'Shaughnessy, Michelle, Ou, Shih-Hsiang, Packham, David, Padiyar, Aparna, Pai, Mei-Fen, Pamplona, Irene Agraz, Pan, Szu-Yu, Pandya, Bhavna, Papadia, Federica, Pardinhas, Clara, Parikh, Nishita, Parikh, Samir, Park, Hyeong Cheon, Park, Jung Tak, Parreira, Lucia, Passerini, Patrizia, Patak, Ramachandra, Patecki, Margret, Patel, Rajan, Patel, Jusmin, Patel Suthar, Meera, Patella, Gemma, Patrikyan, Artashes, Pavlovic, Drasko, Paxton, William, Peh, Chen, Peleg, Yonatan, Pelicano, Josep Miquel Blasco, Peng, Yu-Sen, Pereira de Vicente, Manuel, Perez, Jonay Pantoja, Perez, Erika, Perez de Jose, Ana, Pérez Gómez, María Vanessa, Perez Lluna, Leticia, Peri, Usha, Perico, Norberto, Philipponnet, Carole, Phua, Elaine, Piel, Julia, Pillai, Unnikrishnan, Pilmore, Helen, Plavljanic, Djuro, Plaza, Mercedes Velo, Pollock, Carol, Ponnusamy, Arvind, Ponti, Serena, Powell, Thomas, Pradhan, Nishigandha, Prado, Raul Fernandez, Prkacin, Ingrid, Pruthi, Rishi, Pugh, Dan, Quinn, Sarah, Quintana, Luis F, Raakesh, Lathika, Rabindranath, Kannaiyan, Radermacher, Luc, Radhakrishnan, Jai, Ragy, Omar Sherin Ibrahim, Raichoudhury, Ritesh, Raimundo, Mario, Randone, Paolo, Razavian, Mona, Reichel, Helmut, Reis, Marina, Remuzzi, Giuseppe, Reynolds, Annie, Ricchiuto, Anna, Rico, Ivon Maritza Bobadilla, Rigothier, Claire, Ritchie, Angus, Rivero, Maria Antonieta Azancot, Rizk, Dana, Ro, Han, Rodriguez, Alfred, Rodriguez Garcia, Eva, Roger, Simon, Rony, Mohammad, Rosenberg, Mai, Roueff, Stephane, Rovin, Brad, Roxburgh, Sarah, Ruiz, Mario, Rusinol, Helena Marco, Rychlik, Ivan, Sá, Helena, Salehi, Tania, Sánchez de la Nieta, Maria Dolores, Sanden, Silja, Santockiene, Lina, Santos, Patricia Valerio, Santos, Iara Da Silva, Sargsyan, Mari, Sarnow, Franziska, Sat, Sebahat, Satora, Ewa, Savuk, Ana, Sayer, Matthew, Schlieper, Georg, Schlosser, Mandy, Schmidt-Guertler, Hans, Schockaert, Olivier, Schulte, Kevin, Schulz, Lisa, Selvaskandan, Haresh, Semple, David, Sen, Shaundeep, Seppet, Elviira, Serrano, Antonio Galan, Serre, Jean-Emmanuel, Sevillano, Angel, Shah, Sapna, Shen, Yvonne, Sheridan, Brittany, Shu, Kai-Hsiang, Sightler, Ford, Silva, Sónia, Silva, Arnold, Sinha, Smeeta, Siriwardana, Amanda, Sitas, Zvonimir, Sivo, Carmen, Sizeland, Peter, Sly, Cathylee, Smith, Priscilla, Snow, Brian, Soares, Elsa Sofia Quadrado, Solazzo, Andrea, Solis, Elena Gutierrez, Solomon, Laurence, Song, Young Rim, Sousa, Helena, Spinowitz, Bruce, Stallworthy, Elizabeth, Stamellou, Eleni, Stanczyk, Malgorzata, Stangenberg, Stefanie, Stankovic, Marija, Stankuviene, Asta, Stea, Emma Diletta, Stompor, Tomasz, Storrar, Joshua, Sullivan, James, Sulowicz, Wladyslaw, Suyumova, Irina, Szeto, Cheuk Chun, Tamarit, Esther, Tan, Eddie, Tan, May, Tang, Sydney Chi Wai, Tang, Hon, Teixeira, Catarina, Telling, Kadri, Terrades, Natalia Ramos, Tesar, Vladimir, Tez, Didem, Thervet, Eric, Thibaudin, Damien, Thomas, Mark, Thyagarajan, Nikhil, Tkaczyk, Marcin, Torreggiani, Massimo, Trillini, Matias, Tsai, Shang-Feng, Tsai, Wan-Chuan, Tsai, Jer-Chia, Tseng, Po-Yu, Tumlin, James, Tung, Kuei-Ting, Turnbull, Angus, Udani, Suneel, Uhlinova, Jana, Unt, Kristin, Urciuolo, Federica, Vanacker, An, Vandewiele, Bert, Vaz, Alvaro, Veermae, Kristi, Viaene, Liesbeth, Vickiene, Alvita, Vigano, Sara, Vila, Maria Antonia Munar, Vilayur, Eswari, Villanueva, Caridad Martinez, Villarroya, Cristina Medrano, Villen, Alejandro Soria, Viramontes, Veronica, Vita, Caterina, Vujcic, Dunja, Wahba, Mona, Wan, Susan, Wang, Chih-Hsien, Warling, Xavier, Waters, Gerald, Waugh, Jane, Weiland, Lea, Weiner, Stefan, Weinreich, Thomas, Werth, Stephan Christian, Wickens, Olivia, Wijeratne, Vidu, Wilder, Karen, Willcocks, Lisa, Williams, Allister, Winiarska, Agata, Wirtz, Nikolaus, Wolf, Lothar, Wolf, Gunter, Wong, Muh Geot, Wong, Yick Hei, Wong, Sze Ho Sunny, Workeneh, Biruh, Wu, Ming-Ju, Wu, Hon-Yen, Wyndham, Roger, Yang, Jihyun, Yang, Ju-Yeh, Yeap, Chii, Yim, Ka Fai, Yong, Kenneth, Yoo, Tae-Hyun, Yoon, Songuk, Yu, Tung-Min, Yue, Tak Tai Andrew, Zakari, Michel, Zakauskiene, Urte, Zaoui, Philippe, Zbrzezniak, Justyna, Zielinska, Dorota, Zizzi, Carlotta Federica, Rovin, Brad H, Heerspink, Hiddo J L, Alpers, Charles E, Bieler, Stewart, Diva, Ulysses A, Inrig, Jula K, Kohan, Donald E, Komers, Radko, Małecki, Robert, Mercer, Alex, Noronha, Irene L, Oh, Se Won, Peh, Chen Au, Praga, Manuel, Preciado, Priscila, Rheault, Michelle N, Rote, William E, Tang, Sydney C W, Trachtman, Howard, Trimarchi, Hernán, Tumlin, James A, and Perkovic, Vlado

Published
2023
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4. Sparsentan in patients with IgA nephropathy: a prespecified interim analysis from a randomised, double-blind, active-controlled clinical trial

Author

Alarmartine, Eric, Barratt, Jonathan, Chae, Dong Wan, Del Vecchio, Lucia, Floege, Jurgen, Hwang, Shang-Jyh, Jelakovic, Bojan, Maes, Bart, Malecki, Robert, Miglinas, Marius, Nolasco, Fernando Eduardo Barbosa, Praga, Manual, Rabindranath, Kannaiyan, Rosenberg, Mai, Rovin, Brad, Tang, Sydney Chi Wai, Tesar, Vladmir, Wong, Muh Geot, Bose, Bhadran, Gangadharan, Muralikrishna, McDonald, Stephen, Peh, Chen, Jahan, Sadia, Yeap, Chii, Clayton, Philip, Irish, Georgina, Thyagarajan, Nikhil, Hollett, Peter, Krishnasamy, Rathika, Carroll, Robert, Jesudason, Shilpanjali, Crail, Susan, Coates, Toby, Waugh, Jane, Noble, Euan, Mahadevan, Kumaradevan, Campbell, Victoria, Salehi, Tania, Lim, Wai, Boudville, Neil, Chakera, Aron, Chan, Doris, Krishnan, Anoushka, Eqbal, Yusuf, Gillies, Alastair, Vilayur, Eswari, Maung Myint, Thida Maung, Gray, Nicholas, Cheetham, Melissa, Pollock, Carol, Cooper, Bruce, Mather, Amanda, Roxburgh, Sarah, Shen, Yvonne, Stangenberg, Stefanie, Siriwardana, Amanda, O'Lone, Emma, Wan, Susan, Neuen, Brendon, Tsun Kit Ha, Jeffrey, Kim, Dana, Heath, Lauren, Jain, Arunima, Phua, Elaine, Li, Yan, Gallagher, Martin, Jardine, Meg, Ritchie, Angus, Razavian, Mona, Foote, Celine, Wyndham, Roger, Sen, Shaundeep, Endre, Zoltan, Erlich, Jonathan, Fernando, Mangalee, Yong, Kenneth, Luxton, Grant, Kotwal, Sradha, Roger, Simon, Wijeratne, Vidu, Packham, David, Fraser, Ian, Vandewiele, Bert, Laute, Margo, Lemahieu, Wim, Jamar, Sofie, Ombelet, Sara, Meeus, Gert, Decupere, Marc, Schockaert, Olivier, Doubel, Peter, Viaene, Liesbeth, Radermacher, Luc, Masset, Catherine, Moonen, Martial, Firre, Eric, Milicevic, Martina, Warling, Xavier, Vanacker, An, Malfait, Thomas, Durlen, Ivan, Horvatic, Ivica, Savuk, Ana, Gellineo, Lana, Karanovic, Sandra, Dika, Zivka, Plavljanic, Djuro, Mikacic, Ivana, Trajbar Kentric, Dubravka, Barisic, Dunja, Stankovic, Marija, Majstorovic Barac, Karolina, Kruljac, Ivan, Pavlovic, Drasko, Drinkovic, Martin, Prkacin, Ingrid, Barbic, Jerko, Sitas, Zvonimir, Vujcic, Dunja, Rychlik, Ivan, Benesova, Anna, Drinovska, Klara, Kratka, Karolina, Maixnerova, Dita, Ilmoja, Madis, Unt, Kristin, Lilienthal, Kadri, Auerbach, Asta, Leis, Liisi, Piel, Julia, Adoberg, Annika, Kolvald, Kulli, Veermae, Kristi, Telling, Kadri, Seppet, Elviira, Uhlinova, Jana, Zaoui, Philippe, Carron, Pierre-Louis, Masson, Ingrid, Dinic, Miriana, Thibaudin, Damien, Broyet, Christian, Maillard, Nicolas, Mohey, Hesham, Mariat, Christophe, Claisse, Guillaume, Alamartine, Eric, Dussol, Bertrand, Burtey, Stephane, Chiche-Jourde, Noemie, Serre, Jean-Emmanuel, Jeantet, Guillaume, Chenine, Leila, Blanchard, Anne, Roueff, Stephane, Thervet, Eric, Fouassier, David, Buffet, Alexandre, Livrozet, Marine, Gaisset, Roxane, Karras, Alexandre, Heng, Anne-Elisabeth, Garrouste, Cyril, Philipponnet, Carole, Nicolo, Clementine, Atenza, Alba, Lanaret, Camille, Greze, Clarisse, Mayet, Valentin, Dumond, Clement, Delmas, Yahsou, Combe, Christian, Rigothier, Claire, Burguet, Laure, Labat, Aurore, Mucha, Simon, de Précigout, Valérie, Weinreich, Thomas, Reichel, Helmut, Draganova, Diliana, Wolf, Lothar, Hohenstein, Bernd, Heinrichs, Sven, Kulka, Simone, Sat, Sebahat, Weiland, Lea, Krueger, Thilo, Wolf, Gunter, Kettner, Christiane, Schlosser, Mandy, Herfurth, Johann Konstantin, Koch, Annegret, Busch, Martin, Werth, Stephan Christian, Nitschke, Martin, Cakiroglu, Figen, Sarnow, Franziska, Schulz, Lisa, Weiner, Stefan, Wirtz, Nikolaus, Koester, Eric, Moeller, Marcus, Stamellou, Eleni, Sanden, Silja, Schmidt-Guertler, Hans, Bernhardt, Wanja, Patecki, Margret, Schlieper, Georg, Schulte, Kevin, Girardet, Annette, Kunzendorf, Ulrich, Kwan, Lorraine Pui Yuen, Mok, Maggie Ming Yee, Chan, Gary Chi Wang, Ma, Mingyao, Lie, Davina Ngoi Wah, Chan, Anthony Ting Pong, Szeto, Cheuk Chun, Ng, Kit Chung Jack, Cheung, Siu Fai, Yue, Tak Tai Andrew, Fung, Ka Shun Samuel, Tang, Hon, Yim, Ka Fai, Law, Wai Ping, Wong, Yick Hei, Lam, Chi Kwan Darwin, Wong, Sze Ho Sunny, Marcantoni, Carmelita, Aliotta, Roberta, Deodato, Francesca, Patella, Gemma, Comi, Nicolino, Vita, Caterina, Carullo, Nazareno, Bolignano, Davide, Musolino, Michela, Trillini, Matias, Perico, Norberto, Remuzzi, Giuseppe, Daina, Erica, Biancone, Luigi, Colla, Loredana, Burdese, Manuel, Cogno, Chiara, Boaglio, Elena, Abbasciano, Isabella, Zizzi, Carlotta Federica, Randone, Paolo, Napodano, Pietro, Ricchiuto, Anna, Cassia, Matthias, Accarino, Simone, Cozzolino, Mario, Baccaro, Rocco, Costanzi, Stefano, Di Maio, Federica, Arena, Maria, Urciuolo, Federica, Vigano, Sara, Cavalli, Andrea, Limardo, Monica, Bordoli, Monica, Ponti, Serena, Longhi, Selena, Solazzo, Andrea, Giaroni, Francesco, Donati, Gabriele, Torreggiani, Massimo, Catucci, Davide, Colucci, Marco, Esposito, Vittoria, Esposito, Ciro, Gesualdo, Loreto, Capaccio, Flavia, Diletta Stea, Emma, Sivo, Carmen, Annese, Francesca, Papadia, Federica, Messa, Piergiorgio, Belingheri, Mirco, Passerini, Patrizia, Malvica, Silvia, Vickiene, Alvita, Zakauskiene, Urte, Asakiene, Egle, Bumblyte', Inga Arune, Stankuviene, Asta, Santockiene, Lina, Hayat, Ashik, Williams, Allister, Sizeland, Peter, Tan, Eddie, Waters, Gerald, Chan, Lai Wan, Henderson, Andrew, Turnbull, Angus, McNally, Andrew, Reynolds, Annie, Pilmore, Helen, Dittmer, Ian, Manley, Paul, Stallworthy, Elizabeth, Goh, Tze, Semple, David, Collins, Michael, Curry, Elizabeth, Ahmed, Jafar, Nguyen, Thu, Winiarska, Agata, Zbrzezniak, Justyna, Stompor, Tomasz, Krajewska, Magdalena, Augustyniak-Bartosik, Hanna, Zielinska, Dorota, Jander, Anna, Stanczyk, Malgorzata, Tkaczyk, Marcin, Miarka, Przemyslaw, Aksamit, Dariusz, Jaskowski, Piotr, Sulowicz, Wladyslaw, Cieniawski, Dominik, Gontarek-Kacprzak, Julita, Felicjanczuk, Elzbieta, Kwella, Norbert, Kwella, Bogna, Satora, Ewa, Fernandes, João Carlos, Gomes, Ana Marta, Reis, Marina, Lopes, Daniela, Almeida, Catarina, Sá, Helena, Figueiredo, Ana Carolina, Pardinhas, Clara, Almeida, Edgar, Raimundo, Mario, Cortesão Costa, Ana, Falcao Goncalves, Luis Pedro, Fernandes, Sara, Silva, Sónia, Teixeira, Catarina, Fernandes, Adriana, Nolasco, Fernando, Alves, Patricia, Gois, Mario, Fonseca, Nuno, Messias, Ana, Menezes, Maria, Cardoso, Filipa, Sousa, Helena, Marques, Joana, Barata, Rui, Lopes, Jose Antonio, Jorge, Sofia, Gameiro, Joana, de Almeida Agapito Fonseca, Jose Nuno, Goncalves, Sara, Farinha, Ana, Valerio Santos, Patricia, Natario, Ana, de Jesus Barreto, Jose Carlos, Abrantes, Catarina, Quadrado Soares, Elsa Sofia, Soares Felgueiras, Joana de Sousa, Cunha, Liliana, Parreira, Lucia, Furtado, Teresa, Vaz, Alvaro, Oh, Kook-Hwan, Lee, Hajeong, Joong Kim, Se, Jeong, Jong Cheol, Hoon Kim, Yeong, Kim, Yunmi, Park, Hyeong Cheon, Choi, Hoon Young, Wook Kim, Hyung, Lee, Moon Hyoung, Yoon, Songuk, Lee, Kyu-Beck, Hyun, YoungYoul, Yoo, Tae-Hyun, Han, Seung Hyeok, Park, Jung Tak, Kim, Sunggyun, Song, Young Rim, Kim, Jwa-Kyung, Lee, Hyung-seok, Joo, Narae, Lee, JungEun, Ryoun Jang, Hye, Jeon, Junseok, Chung, Wookyung, Lee, HyunHee, Chang, Jae Hyun, Chun, Ka Yeong, Jung, Ji Yong, Ro, Han, Kim, Aejin, Jo, Sang-Kyung, Yang, Jihyun, Kim, Myung-Gyu, Oh, SeWon, Martinez Villanueva, Caridad, Gimeno, Ana Vilar, Andres Useche Bonilla, Gustavo, Tamarit, Esther, Galan Serrano, Antonio, Verde Moreno, Eduardo, Fernandez, Jose Luño, Goicoechea Diezhandino, Maria Angeles, Verdalles Guzman, Ursula, de Jose, Ana Perez, Ortiz Arduan, Alberto, Pérez Gómez, María Vanessa, Martín Cleary, Catalina, Prado, Raul Fernandez, Goma, Elena, Ballarin, Jose, Encarnacion, Montserrat Diaz, Da Silva Santos, Iara, Marco Rusinol, Helena, Furlano, Monica, Arias, Carlos, Barrios, Clara, Garcia, Eva Rodriguez, Sierra Ochoa, Adriana, Vizcaino Castillo, Belen, Pantoja Perez, Jonay, Gonzalez Moya, Mercedes, Sargsyan, Mari, Calatayud Aristoy, Emma, Bernabeu, Ana Avila, Perez Lluna, Leticia, Malek Marin, Tamara, Antonia Munar Vila, Maria, Bobadilla Rico, Ivon Maritza, Allende Burgos, Natalia, Gutierrez Martinez, Eduardo, Gutierrez Solis, Elena, Sevillano, Angel, Merida Herrero, Evangelina, Miquel Blasco Pelicano, Josep, Rodas Marin, Lida Maria, Quintana, Luis F, Antonieta Azancot Rivero, Maria, Ramos Terrades, Natalia, Garcia Carro, Clara, Agraz Pamplona, Irene, Salgueira Lazo, Mercedes, de la Prada Alvarez, Francisco, Alonso Garcia, Fabiola, Adrian Aguilera Morales, Wenceslao, Virxinia Pol Heres, Salia, Forcen, Angel, Parra Moncasi, Eduardo, Medrano Villarroya, Cristina, Soria Villen, Alejandro, Gracia Garcia, Olga, Velo Plaza, Mercedes, Sánchez de la Nieta, Maria Dolores, Calvo Arevalo, Marta, Moreno, Antolina, Cigarran Guldris, Secundino, de Vicente, Manuel Pereira, Munar Vila, Maria Antonia, Hsu, Bang-Gee, Wang, Chih-Hsien, Chen, Cheng-Hsu, Yu, Tung-Min, Wu, Ming-Ju, Tsai, Shang-Feng, Hsu, Chia-Tien, Chiu, Hsien-Fu, Chou, Kang-Ju, Fang, Hua-Chang, Lee, Po-Tsang, Chen, Hsin-Yu, Chen, Chien-Liang, Huang, Chien-Wei, Ou, Shih-Hsiang, Ho, Tzung-Yo, Hsu, Chih-Yang, Chang, Ming-Shan, Chiu, Yen-Ling, Peng, Yu-Sen, Shu, Kai-Hsiang, Pan, Szu-Yu, Hsu, Shih-Ping, Yang, Ju-Yeh, Pai, Mei-Fen, Tseng, Po-Yu, Wu, Hon-Yen, Tsai, Wan-Chuan, Tung, Kuei-Ting, Chen, Hung-Yuan, Chen, Hung-Chun, Kuo, Mei-Chuan, Hwang, Daw-Yang, Chiu, Yi-Wen, Hung, Chi-Chih, Kuo, Hung-Tien, Tsai, Jer-Chia, McCafferty, Kieran, Forbes, Suzanne, Dasgupta, Indranil, Thomas, Mark, Mahdi, Amar, Ajayi, Bamidele, Chowdhury, Paramit, Kasimatis, Theodoros, Moutzouris, Dimitrios, Dudreuilh, Caroline, Pruthi, Rishi, Mansfield, Nick, Doctor, Gabriel, Shah, Sapna, Kon, Sui, Smith, Priscilla, Hamilton, Patrick, Kanigicherla, Durga, Ibrahim Ragy, Omar Sherin, Alchi, Bassam, Flossmann, Oliver, Ghalli, Farid, Lawman, Sarah, Sinha, Smeeta, Chrysochou, Constantina, Chukwu, Chukwuma, Maire De Bhailis, Aine, Al Chalabi, Saif, Hudson, Amy, Gopu, Arun, Wickens, Olivia, Storrar, Joshua, Wahba, Mona, Lorde, Nathan, Rony, Mohammad, Griffin, Sian, Latif, Farah, Ali, Mohammad, DaSilva, Louise, Ayling-Smith, Jonathan, Mahdi, Eamon, Willcocks, Lisa, Jones, Rachel, Cheung, Chee Kay, Selvaskandan, Haresh, Pugh, Dan, Sayer, Matthew, Dhaun, Neeraj, Chapman, Fiona, Mark, Patrick, Geddes, Colin, McQuarrie, Emily, Patel, Rajan, Solomon, Laurence, Ponnusamy, Arvind, Morris, Adam, Okoh, Pedro, Floyd, Lauren, Dhaygude, Ajay, Leung, Janson, Goldsmith, Christopher, Pandya, Bhavna, Tez, Didem, Mikhail, Ashraf, Brown, Karen, Bucknall, Thomas, Lambie, Mark, Comunale, Roderick, Brandon, Donald, Martinez, Stacy, Hall, Amanda, Henderson, Amy, Fearday, Aaron, Douthit, Nicole, Snow, Brian, Silva, Arnold, Sly, Cathylee, Keller, Christopher, Davidson, Robert, Meng, Jerry, Haws, Robert, Kattamanchi, Siddhartha, Mojarrab, Javad, Pillai, Unnikrishnan, Lafayette, Richard, O'Shaughnessy, Michelle, Kamal, Fahameedah, Mehta, Kshama, Baker, Bruce, Ruiz, Mario, Jyothinagaram, Praveena, Peri, Usha, Paxton, William, Tumlin, James, McGreal, Kerri, McCarthy, Ellen, Kimber, Cassandra, Gautam, Archana, Khalil, Kassem, Nguyen, Viet, Minasian, Raffi, Arfaania, Dariush, Daneshvari, Sam, Zakari, Michel, Patrikyan, Artashes, Afsari, Rouzbeh, Ayvazyan, Christine, Fakih, Faisal, Lagatta, Mark, Rodriguez, Alfred, Avella, Jorge Enrique Monroy, Patak, Ramachandra, Kadakia, Jigar, Radhakrishnan, Jai, Appel, Gerald, Ahn, Wooin, Nelson, Bradley, Medina, Allyson, Ahmad, Syeda, Peleg, Yonatan, Clement, Nisha, Chiu, Ian, Hendren, Elizabeth, Bomback, Andrew, Canetta, Pietro, Spinowitz, Bruce, Charytan, Chaim, Parikh, Nishita, Kuo, Sheng, Raichoudhury, Ritesh, Dobre, Mirela, Negrea, Lavinia, Padiyar, Aparna, Jittirat, Arksarapuk, Pradhan, Nishigandha, Dhelaria, Ranjit, Balamuthusamy, Saravanan, Madhrira, Machaiah, Powell, Thomas, Lifland, Howard, Bailey, Asha, Ford Sightler, Sarah Ashley, Suthar, Meera Patel, Green, Heather, Parikh, Samir, Ayoub, Isabelle, Almaani, Salem, Contreras, Gabriel, Fornoni, Alessia, Drexler, Yelena, Geara, Abdallah, Sheridan, Brittany, Coppock, Gaia, Hogan, Jonathan, Gonzalez, Carlos, Bhadra, Shamik, Chowdhury, Pradip, Kyaw, Kay, Tan, May, Raakesh, Lathika, Mendoza, Elder, Viramontes, Veronica, Chaudhry, Asghar, Carbonell, Juan, Gadh, Rajdeep, Fernandez, Victor, Kassem, Mohamad, Jacob, Radu, Wilder, Karen, Newsome, Britt, Klamm, Kathryn, Suyumova, Irina, Kooienga, Laura Ann, Janko, Catherine, Rizk, Dana, Julian, Bruce, Caster, Dawn, Perez, Erika, Garg, Gunjan, Gowda, Nayan, Udani, Suneel, Mandayam, Sreedhar, Workeneh, Biruh, Assefi, Ali, Greco, Barbara, Germain, Michael, Patel, Jusmin, Quinn, Sarah, Sullivan, James, Glaze, Jeffrey, Madonia, Phillip, McMahon, Kellyn, Giles, Harold, Adler, Sharon, Dai, Tiane, Heerspink, Hiddo J L, Alpers, Charles E, Bieler, Stewart, Diva, Ulysses, Inrig, Jula, Komers, Radko, Mercer, Alex, Noronha, Irene L, Rheault, Michelle N, Rote, William, Trachtman, Howard, Trimarchi, Hernán, and Perkovic, Vlado

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2023
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5. Association of Treatment Effects on Early Change in Urine Protein and Treatment Effects on GFR Slope in IgA Nephropathy: An Individual Participant Meta-analysis

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Inker, Lesley A., Heerspink, Hiddo J.L., Tighiouart, Hocine, Chaudhari, Juhi, Miao, Shiyuan, Diva, Ulysses, Mercer, Alex, Appel, Gerald B., Donadio, James V., Floege, Jürgen, Li, Philip K.T., Maes, Bart D., Locatelli, Francesco, Praga, Manuel, Schena, Francesco P., Levey, Andrew S., and Greene, Tom

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2021
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9. Efficacy and safety of sparsentan versus irbesartan in patients with IgA nephropathy (PROTECT): 2-year results from a randomised, active-controlled, phase 3 trial

Author

Rovin, Brad H, primary, Barratt, Jonathan, additional, Heerspink, Hiddo J L, additional, Alpers, Charles E, additional, Bieler, Stewart, additional, Chae, Dong-Wan, additional, Diva, Ulysses A, additional, Floege, Jürgen, additional, Gesualdo, Loreto, additional, Inrig, Jula K, additional, Kohan, Donald E, additional, Komers, Radko, additional, Kooienga, Laura Ann, additional, Lafayette, Richard, additional, Maes, Bart, additional, Małecki, Robert, additional, Mercer, Alex, additional, Noronha, Irene L, additional, Oh, Se Won, additional, Peh, Chen Au, additional, Praga, Manuel, additional, Preciado, Priscila, additional, Radhakrishnan, Jai, additional, Rheault, Michelle N, additional, Rote, William E, additional, Tang, Sydney C W, additional, Tesar, Vladimir, additional, Trachtman, Howard, additional, Trimarchi, Hernán, additional, Tumlin, James A, additional, Wong, Muh Geot, additional, Perkovic, Vlado, additional, Abbasciano, Isabella, additional, Abrantes, Catarina, additional, Accarino, Simone, additional, Adler, Sharon, additional, Adoberg, Annika, additional, Afsari, Rouzbeh, additional, Ahmad, Syeda, additional, Ahmed, Jafar, additional, Ahn, Wooin, additional, Ajayi, Bamidele, additional, Aksamit, Dariusz, additional, Al Chalabi, Saif, additional, Alamartine, Eric, additional, Alchi, Bassam, additional, Ali, Mohammad, additional, Aliotta, Roberta, additional, Almaani, Salem, additional, Almeida, Catarina, additional, Almeida, Edgar, additional, Alvarez, Francisco de la Prada, additional, Alves, Patricia, additional, Annese, Francesca, additional, Appel, Gerald, additional, Arduan, Alberto Ortiz, additional, Arena, Maria, additional, Arevalo, Marta Calvo, additional, Arfaania, Dariush, additional, Arias, Carlos, additional, Aristoy, Emma Calatayud, additional, Asakiene, Egle, additional, Ashley, Sarah, additional, Assefi, Ali, additional, Atenza, Alba, additional, Auerbach, Asta, additional, Augustyniak-Bartosik, Hanna, additional, Avella, Monroy, additional, Ayling-Smith, Jonathan, additional, Ayoub, Isabelle, additional, Ayvazyan, Christine, additional, Baccaro, Rocco, additional, Bailey, Asha, additional, Baker, Bruce, additional, Balamuthusamy, Saravanan, additional, Ballarin, Jose, additional, Barata, Rui, additional, Barbic, Jerko, additional, Barisic, Dunja, additional, Barreto, Jose Carlos de Jesus, additional, Barrios, Clara, additional, Belingheri, Mirco, additional, Benesova, Anna, additional, Bernabeu, Ana Avila, additional, Bernhardt, Wanja, additional, Bhadra, Shamik, additional, Biancone, Luigi, additional, Blanchard, Anne, additional, Boaglio, Elena, additional, Bolignano, Davide, additional, Bomback, Andrew, additional, Bonilla, Gustavo Andres Useche, additional, Bordoli, Monica, additional, Bose, Bhadran, additional, Boudville, Neil, additional, Brandon, Donald, additional, Brown, Karen, additional, Broyet, Christian, additional, Bucknall, Thomas, additional, Buffet, Alexandre, additional, Bumblyte', Inga Arune, additional, Burdese, Manuel, additional, Burgos, Natalia Allende, additional, Burguet, Laure, additional, Burtey, Stephane, additional, Busch, Martin, additional, Cakiroglu, Figen, additional, Campbell, Victoria, additional, Canetta, Pietro, additional, Capaccio, Flavia, additional, Carbonell, Juan, additional, Cardoso, Filipa, additional, Carro, Clara Garcia, additional, Carroll, Robert, additional, Carron, Pierre-Louis, additional, Carullo, Nazareno, additional, Cassia, Matthias, additional, Caster, Dawn, additional, Castillo, Belen Vizcaino, additional, Catucci, Davide, additional, Cavalli, Andrea, additional, Chakera, Aron, additional, Chan, Doris, additional, Chan, Gary Chi Wang, additional, Chan, Anthony Ting Pong, additional, Chan, Lai Wan, additional, Chang, Jae Hyun, additional, Chang, Ming-Shan, additional, Chapman, Fiona, additional, Charytan, Chaim, additional, Chaudhry, Asghar, additional, Cheetham, Melissa, additional, Chen, Cheng-Hsu, additional, Chen, Hsin-Yu, additional, Chen, Chien-Liang, additional, Chen, Hung-Yuan, additional, Chen, Hung-Chun, additional, Chenine, Leila, additional, Cheung, Siu Fai, additional, Cheung, Chee Kay, additional, Chiche-Jourde, Noemie, additional, Chiu, Hsien-Fu, additional, Chiu, Yen-Ling, additional, Chiu, Yi-Wen, additional, Chiu, Ian, additional, Choi, Hoon Young, additional, Chou, Kang-Ju, additional, Chowdhury, Paramit, additional, Chowdhury, Pradip, additional, Chrysochou, Constantina, additional, Chukwu, Chukwuma, additional, Chun, Ka Yeong, additional, Chung, Wookyung, additional, Cieniawski, Dominik, additional, Claisse, Guillaume, additional, Clayton, Philip, additional, Cleary, Catalina Martín, additional, Clement, Nisha, additional, Coates, Toby, additional, Cogno, Chiara, additional, Colla, Loredana, additional, Collins, Michael, additional, Colucci, Marco, additional, Combe, Christian, additional, Comi, Nicolino, additional, Comunale, Roderick, additional, Contreras, Gabriel, additional, Cooper, Bruce, additional, Coppock, Gaia, additional, Costa, Ana Cortesão, additional, Costanzi, Stefano, additional, Cozzolino, Mario, additional, Crail, Susan, additional, Cunha, Liliana, additional, Curry, Elizabeth, additional, Dai, Tiane, additional, Daina, Erica, additional, Daneshvari, Sam, additional, Dasgupta, Indranil, additional, DaSilva, Louise, additional, Davidson, Robert, additional, De Bhailis, Aine Maire, additional, de Précigout, Valérie, additional, Decupere, Marc, additional, Delmas, Yahsou, additional, Deodato, Francesca, additional, Dhaun, Neeraj, additional, Dhaygude, Ajay, additional, Dhelaria, Ranjit, additional, Di Maio, Federica, additional, Diezhandino, Maria Angeles Goicoechea, additional, Dika, Zivka, additional, Dinic, Miriana, additional, Dittmer, Ian, additional, Dobre, Mirela, additional, Doctor, Gabriel, additional, Donati, Gabriele, additional, Doubel, Peter, additional, Douthit, Nicole, additional, Draganova, Diliana, additional, Drexler, Yelena, additional, Drinkovic, Martin, additional, Drinovska, Klara, additional, Dudreuilh, Caroline, additional, Dumond, Clement, additional, Durlen, Ivan, additional, Dussol, Bertrand, additional, Encarnacion, Montserrat Diaz, additional, Endre, Zoltan, additional, Enrique, Jorge, additional, Eqbal, Yusuf, additional, Erlich, Jonathan, additional, Esposito, Vittoria, additional, Esposito, Ciro, additional, Fakih, Faisal, additional, Fang, Hua-Chang, additional, Farinha, Ana, additional, Fearday, Aaron, additional, Felgueiras, Joana de Sousa Soares, additional, Felicjanczuk, Elzbieta, additional, Fernandes, João Carlos, additional, Fernandes, Sara, additional, Fernandes, Adriana, additional, Fernandez, Jose Luño, additional, Fernandez, Victor, additional, Fernando, Mangalee, additional, Figueiredo, Ana Carolina, additional, Firre, Eric, additional, Flossmann, Oliver, additional, Floyd, Lauren, additional, Fonseca, Nuno, additional, Fonseca, Jose Nuno de Almeida Agapito, additional, Foote, Celine, additional, Forbes, Suzanne, additional, Forcen, Angel, additional, Fornoni, Alessia, additional, Fouassier, David, additional, Fraser, Ian, additional, Fung, Ka Shun Samuel, additional, Furlano, Monica, additional, Furtado, Teresa, additional, Gadh, Rajdeep, additional, Gaisset, Roxane, additional, Gallagher, Martin, additional, Gameiro, Joana, additional, Gangadharan, Muralikrishna, additional, Garcia, Fabiola Alonso, additional, Garcia, Olga Gracia, additional, Garg, Gunjan, additional, Garrouste, Cyril, additional, Gautam, Archana, additional, Geara, Abdallah, additional, Geddes, Colin, additional, Gellineo, Lana, additional, Germain, Michael, additional, Ghalli, Farid, additional, Giaroni, Francesco, additional, Giles, Harold, additional, Gillies, Alastair, additional, Gimeno, Ana Vilar, additional, Girardet, Annette, additional, Glaze, Jeffrey, additional, Goh, Tze, additional, Gois, Mario, additional, Goldsmith, Christopher, additional, Goma, Elena, additional, Gomes, Ana Marta, additional, Goncalves, Luis Pedro Falcao, additional, Goncalves, Sara, additional, Gontarek-Kacprzak, Julita, additional, Gonzalez, Carlos, additional, Gopu, Arun, additional, Gowda, Nayan, additional, Gray, Nicholas, additional, Greco, Barbara, additional, Green, Heather, additional, Greze, Clarisse, additional, Griffin, Sian, additional, Guldris, Secundino Cigarran, additional, Guzman, Ursula Verdalles, additional, Ha, Jeffrey Tsun Kit, additional, Hall, Amanda, additional, Hamilton, Patrick, additional, Han, Seung Hyeok, additional, Haws, Robert, additional, Hayat, Ashik, additional, Heath, Lauren, additional, Heinrichs, Sven, additional, Henderson, Andrew, additional, Henderson, Amy, additional, Hendren, Elizabeth, additional, Heng, Anne-Elisabeth, additional, Heres, Salia Virxinia Pol, additional, Herfurth, Johann Konstantin, additional, Herrero, Evangelina Merida, additional, Ho, Tzung-Yo, additional, Hogan, Jonathan, additional, Hohenstein, Bernd, additional, Hollett, Peter, additional, Horvatic, Ivica, additional, Hsu, Bang-Gee, additional, Hsu, Chia-Tien, additional, Hsu, Chih-Yang, additional, Hsu, Shih-Ping, additional, Huang, Chien-Wei, additional, Hudson, Amy, additional, Hung, Chi-Chih, additional, Hwang, Shang-Jyh, additional, Hwang, Daw-Yang, additional, Hyun, Young Youl, additional, Ilmoja, Madis, additional, Irish, Georgina, additional, Jacob, Radu, additional, Jahan, Sadia, additional, Jain, Arunima, additional, Jamar, Sofie, additional, Jander, Anna, additional, Jang, Hye Ryoun, additional, Janko, Catherine, additional, Jardine, Meg, additional, Jaskowski, Piotr, additional, Jeantet, Guillaume, additional, Jelakovic, Bojan, additional, Jeon, Junseok, additional, Jeong, Jong Cheol, additional, Jesudason, Shilpanjali, additional, Jittirat, Arksarapuk, additional, Jo, Sang-Kyung, additional, Jones, Rachel, additional, Joo, Narae, additional, Jorge, Sofia, additional, Julian, Bruce, additional, Jung, JiYong, additional, Jyothinagaram, Praveena, additional, Kadakia, Jigar, additional, Kamal, Fahameedah, additional, Kanigicherla, Durga, additional, Karanovic, Sandra, additional, Karras, Alexandre, additional, Kasimatis, Theodoros, additional, Kassem, Mohamad, additional, Kattamanchi, Siddhartha, additional, Keller, Christopher, additional, Kentric, Dubravka Trajbar, additional, Kettner, Christiane, additional, Khalil, Kassem, additional, Kim, Dana, additional, Kim, Se Joong, additional, Kim, Yeong Hoon, additional, Kim, Yunmi, additional, Kim, Hyung Wook, additional, Kim, Sunggyun, additional, Kim, Jwa-Kyung, additional, Kim, Aejin, additional, Kim, Myung-Gyu, additional, Kimber, Cassandra, additional, Klamm, Kathryn, additional, Koch, Annegret, additional, Koester, Eric, additional, Kolvald, Kulli, additional, Kon, Sui, additional, Kotwal, Sradha, additional, Krajewska, Magdalena, additional, Kratka, Karolina, additional, Krishnan, Anoushka, additional, Krishnasamy, Rathika, additional, Krueger, Thilo, additional, Kruljac, Ivan, additional, Kulka, Simone, additional, Kunzendorf, Ulrich, additional, Kuo, Mei-Chuan, additional, Kuo, Hung-Tien, additional, Kuo, Sheng, additional, Kwan, Lorraine Pui Yuen, additional, Kwella, Norbert, additional, Kwella, Bogna, additional, Kyaw, Kay, additional, Labat, Aurore, additional, Lagatta, Mark, additional, Lam, Chi Kwan Darwin, additional, Lambie, Mark, additional, Lanaret, Camille, additional, Latif, Farah, additional, Laute, Margo, additional, Law, Wai Ping, additional, Lawman, Sarah, additional, Lazo, Mercedes Salgueira, additional, Lee, Hajeong, additional, Lee, Moon Hyoung, additional, Lee, Kyu-Beck, additional, Lee, Hyung-seok, additional, Lee, JungEun, additional, Lee, Hyun Hee, additional, Lee, Po-Tsang, additional, Leis, Liisi, additional, Lemahieu, Wim, additional, Leung, Janson, additional, Li, Yan, additional, Lie, Davina Ngoi Wah, additional, Lifland, Howard, additional, Lilienthal, Kadri, additional, Lim, Wai, additional, Limardo, Monica, additional, Livrozet, Marine, additional, Longhi, Selena, additional, Lopes, Daniela, additional, Lopes, Jose Antonio, additional, Lorde, Nathan, additional, Luxton, Grant, additional, Ma, Mingyao, additional, Madhrira, Machaiah, additional, Madonia, Phillip, additional, Mahadevan, Kumaradevan, additional, Mahdi, Amar, additional, Mahdi, Eamon, additional, Maillard, Nicolas, additional, Maixnerova, Dita, additional, Majstorovic Barac, Karolina, additional, Malecki, Robert, additional, Malfait, Thomas, additional, Malvica, Silvia, additional, Mandayam, Sreedhar, additional, Manley, Paul, additional, Mansfield, Nick, additional, Marcantoni, Carmelita, additional, Mariat, Christophe, additional, Marin, Tamara Malek, additional, Marin, Lida Maria Rodas, additional, Mark, Patrick, additional, Marques, Joana, additional, Martinez, Eduardo Gutierrez, additional, Martinez, Stacy, additional, Masset, Catherine, additional, Masson, Ingrid, additional, Mather, Amanda, additional, Maung Myint, Thida Maung, additional, Mayet, Valentin, additional, McCafferty, Kieran, additional, McCarthy, Ellen, additional, McDonald, Stephen, additional, McGreal, Kerri, additional, McMahon, Kellyn, additional, McNally, Andrew, additional, McQuarrie, Emily, additional, Medina, Allyson, additional, Meeus, Gert, additional, Mehta, Kshama, additional, Mendoza, Elder, additional, Menezes, Maria, additional, Meng, Jerry, additional, Messa, Piergiorgio, additional, Messias, Ana, additional, Miarka, Przemyslaw, additional, Miglinas, Marius, additional, Mikacic, Ivana, additional, Mikhail, Ashraf, additional, Milicevic, Martina, additional, Minasian, Raffi, additional, Moeller, Marcus, additional, Mohey, Hesham, additional, Mojarrab, Javad, additional, Mok, Maggie Ming Yee, additional, Moncasi, Eduardo Parra, additional, Moonen, Martial, additional, Morales, Wenceslao Adrian Aguilera, additional, Moreno, Eduardo Verde, additional, Moreno, Antolina, additional, Morris, Adam, additional, Moutzouris, Dimitrios, additional, Moya, Mercedes Gonzalez, additional, Mucha, Simon, additional, Musolino, Michela, additional, Napodano, Pietro, additional, Natario, Ana, additional, Negrea, Lavinia, additional, Nelson, Bradley, additional, Neuen, Brendon, additional, Newsome, Britt, additional, Ng, Kit Chung Jack, additional, Nguyen, Thu, additional, Nguyen, Viet, additional, Nicolo, Clementine, additional, Nitschke, Martin, additional, Noble, Euan, additional, Nolasco, Fernando, additional, O'Lone, Emma, additional, Ochoa, Adriana Sierra, additional, Oh, Kook-Hwan, additional, Oh, SeWon, additional, Okoh, Pedro, additional, Ombelet, Sara, additional, O'Shaughnessy, Michelle, additional, Ou, Shih-Hsiang, additional, Packham, David, additional, Padiyar, Aparna, additional, Pai, Mei-Fen, additional, Pamplona, Irene Agraz, additional, Pan, Szu-Yu, additional, Pandya, Bhavna, additional, Papadia, Federica, additional, Pardinhas, Clara, additional, Parikh, Nishita, additional, Parikh, Samir, additional, Park, Hyeong Cheon, additional, Park, Jung Tak, additional, Parreira, Lucia, additional, Passerini, Patrizia, additional, Patak, Ramachandra, additional, Patecki, Margret, additional, Patel, Rajan, additional, Patel, Jusmin, additional, Patel Suthar, Meera, additional, Patella, Gemma, additional, Patrikyan, Artashes, additional, Pavlovic, Drasko, additional, Paxton, William, additional, Peh, Chen, additional, Peleg, Yonatan, additional, Pelicano, Josep Miquel Blasco, additional, Peng, Yu-Sen, additional, Pereira de Vicente, Manuel, additional, Perez, Jonay Pantoja, additional, Perez, Erika, additional, Perez de Jose, Ana, additional, Pérez Gómez, María Vanessa, additional, Perez Lluna, Leticia, additional, Peri, Usha, additional, Perico, Norberto, additional, Philipponnet, Carole, additional, Phua, Elaine, additional, Piel, Julia, additional, Pillai, Unnikrishnan, additional, Pilmore, Helen, additional, Plavljanic, Djuro, additional, Plaza, Mercedes Velo, additional, Pollock, Carol, additional, Ponnusamy, Arvind, additional, Ponti, Serena, additional, Powell, Thomas, additional, Pradhan, Nishigandha, additional, Prado, Raul Fernandez, additional, Prkacin, Ingrid, additional, Pruthi, Rishi, additional, Pugh, Dan, additional, Quinn, Sarah, additional, Quintana, Luis F, additional, Raakesh, Lathika, additional, Rabindranath, Kannaiyan, additional, Radermacher, Luc, additional, Ragy, Omar Sherin Ibrahim, additional, Raichoudhury, Ritesh, additional, Raimundo, Mario, additional, Randone, Paolo, additional, Razavian, Mona, additional, Reichel, Helmut, additional, Reis, Marina, additional, Remuzzi, Giuseppe, additional, Reynolds, Annie, additional, Ricchiuto, Anna, additional, Rico, Ivon Maritza Bobadilla, additional, Rigothier, Claire, additional, Ritchie, Angus, additional, Rivero, Maria Antonieta Azancot, additional, Rizk, Dana, additional, Ro, Han, additional, Rodriguez, Alfred, additional, Rodriguez Garcia, Eva, additional, Roger, Simon, additional, Rony, Mohammad, additional, Rosenberg, Mai, additional, Roueff, Stephane, additional, Rovin, Brad, additional, Roxburgh, Sarah, additional, Ruiz, Mario, additional, Rusinol, Helena Marco, additional, Rychlik, Ivan, additional, Sá, Helena, additional, Salehi, Tania, additional, Sánchez de la Nieta, Maria Dolores, additional, Sanden, Silja, additional, Santockiene, Lina, additional, Santos, Patricia Valerio, additional, Santos, Iara Da Silva, additional, Sargsyan, Mari, additional, Sarnow, Franziska, additional, Sat, Sebahat, additional, Satora, Ewa, additional, Savuk, Ana, additional, Sayer, Matthew, additional, Schlieper, Georg, additional, Schlosser, Mandy, additional, Schmidt-Guertler, Hans, additional, Schockaert, Olivier, additional, Schulte, Kevin, additional, Schulz, Lisa, additional, Selvaskandan, Haresh, additional, Semple, David, additional, Sen, Shaundeep, additional, Seppet, Elviira, additional, Serrano, Antonio Galan, additional, Serre, Jean-Emmanuel, additional, Sevillano, Angel, additional, Shah, Sapna, additional, Shen, Yvonne, additional, Sheridan, Brittany, additional, Shu, Kai-Hsiang, additional, Sightler, Ford, additional, Silva, Sónia, additional, Silva, Arnold, additional, Sinha, Smeeta, additional, Siriwardana, Amanda, additional, Sitas, Zvonimir, additional, Sivo, Carmen, additional, Sizeland, Peter, additional, Sly, Cathylee, additional, Smith, Priscilla, additional, Snow, Brian, additional, Soares, Elsa Sofia Quadrado, additional, Solazzo, Andrea, additional, Solis, Elena Gutierrez, additional, Solomon, Laurence, additional, Song, Young Rim, additional, Sousa, Helena, additional, Spinowitz, Bruce, additional, Stallworthy, Elizabeth, additional, Stamellou, Eleni, additional, Stanczyk, Malgorzata, additional, Stangenberg, Stefanie, additional, Stankovic, Marija, additional, Stankuviene, Asta, additional, Stea, Emma Diletta, additional, Stompor, Tomasz, additional, Storrar, Joshua, additional, Sullivan, James, additional, Sulowicz, Wladyslaw, additional, Suyumova, Irina, additional, Szeto, Cheuk Chun, additional, Tamarit, Esther, additional, Tan, Eddie, additional, Tan, May, additional, Tang, Sydney Chi Wai, additional, Tang, Hon, additional, Teixeira, Catarina, additional, Telling, Kadri, additional, Terrades, Natalia Ramos, additional, Tez, Didem, additional, Thervet, Eric, additional, Thibaudin, Damien, additional, Thomas, Mark, additional, Thyagarajan, Nikhil, additional, Tkaczyk, Marcin, additional, Torreggiani, Massimo, additional, Trillini, Matias, additional, Tsai, Shang-Feng, additional, Tsai, Wan-Chuan, additional, Tsai, Jer-Chia, additional, Tseng, Po-Yu, additional, Tumlin, James, additional, Tung, Kuei-Ting, additional, Turnbull, Angus, additional, Udani, Suneel, additional, Uhlinova, Jana, additional, Unt, Kristin, additional, Urciuolo, Federica, additional, Vanacker, An, additional, Vandewiele, Bert, additional, Vaz, Alvaro, additional, Veermae, Kristi, additional, Viaene, Liesbeth, additional, Vickiene, Alvita, additional, Vigano, Sara, additional, Vila, Maria Antonia Munar, additional, Vilayur, Eswari, additional, Villanueva, Caridad Martinez, additional, Villarroya, Cristina Medrano, additional, Villen, Alejandro Soria, additional, Viramontes, Veronica, additional, Vita, Caterina, additional, Vujcic, Dunja, additional, Wahba, Mona, additional, Wan, Susan, additional, Wang, Chih-Hsien, additional, Warling, Xavier, additional, Waters, Gerald, additional, Waugh, Jane, additional, Weiland, Lea, additional, Weiner, Stefan, additional, Weinreich, Thomas, additional, Werth, Stephan Christian, additional, Wickens, Olivia, additional, Wijeratne, Vidu, additional, Wilder, Karen, additional, Willcocks, Lisa, additional, Williams, Allister, additional, Winiarska, Agata, additional, Wirtz, Nikolaus, additional, Wolf, Lothar, additional, Wolf, Gunter, additional, Wong, Yick Hei, additional, Wong, Sze Ho Sunny, additional, Workeneh, Biruh, additional, Wu, Ming-Ju, additional, Wu, Hon-Yen, additional, Wyndham, Roger, additional, Yang, Jihyun, additional, Yang, Ju-Yeh, additional, Yeap, Chii, additional, Yim, Ka Fai, additional, Yong, Kenneth, additional, Yoo, Tae-Hyun, additional, Yoon, Songuk, additional, Yu, Tung-Min, additional, Yue, Tak Tai Andrew, additional, Zakari, Michel, additional, Zakauskiene, Urte, additional, Zaoui, Philippe, additional, Zbrzezniak, Justyna, additional, Zielinska, Dorota, additional, and Zizzi, Carlotta Federica, additional

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2023
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10. Prevalence of cerebrotendinous xanthomatosis among patients diagnosed with early-onset idiopathic bilateral cataracts: final analysis

Author

Freedman, Sharon F., primary, Del Monte, Monte A., additional, Diva, Ulysses, additional, Donahue, Sean P., additional, Drack, Arlene V., additional, Dutta, Rana, additional, Fung, Simon S.M., additional, Imperiale, Michael, additional, Jordan, Catherine O., additional, Lenhart, Phoebe D., additional, Lim, Maria E., additional, McCourt, Emily A., additional, Nihalani, Bharti R., additional, Sabahi, Tarlan, additional, Stahl, Erin D., additional, Miraldi Utz, Virginia A., additional, Wilson, M. Edward, additional, Yen, Kimberly G., additional, and VanderVeen, Deborah K., additional

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2023
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11. Sparsentan in patients with IgA nephropathy: a prespecified interim analysis from a randomised, double-blind, active-controlled clinical trial

Author

Heerspink, Hiddo J L, primary, Radhakrishnan, Jai, additional, Alpers, Charles E, additional, Barratt, Jonathan, additional, Bieler, Stewart, additional, Diva, Ulysses, additional, Inrig, Jula, additional, Komers, Radko, additional, Mercer, Alex, additional, Noronha, Irene L, additional, Rheault, Michelle N, additional, Rote, William, additional, Rovin, Brad, additional, Trachtman, Howard, additional, Trimarchi, Hernán, additional, Wong, Muh Geot, additional, Perkovic, Vlado, additional, Alarmartine, Eric, additional, Chae, Dong Wan, additional, Del Vecchio, Lucia, additional, Floege, Jurgen, additional, Hwang, Shang-Jyh, additional, Jelakovic, Bojan, additional, Maes, Bart, additional, Malecki, Robert, additional, Miglinas, Marius, additional, Nolasco, Fernando Eduardo Barbosa, additional, Praga, Manual, additional, Rabindranath, Kannaiyan, additional, Rosenberg, Mai, additional, Tang, Sydney Chi Wai, additional, Tesar, Vladmir, additional, Bose, Bhadran, additional, Gangadharan, Muralikrishna, additional, McDonald, Stephen, additional, Peh, Chen, additional, Jahan, Sadia, additional, Yeap, Chii, additional, Clayton, Philip, additional, Irish, Georgina, additional, Thyagarajan, Nikhil, additional, Hollett, Peter, additional, Krishnasamy, Rathika, additional, Carroll, Robert, additional, Jesudason, Shilpanjali, additional, Crail, Susan, additional, Coates, Toby, additional, Waugh, Jane, additional, Noble, Euan, additional, Mahadevan, Kumaradevan, additional, Campbell, Victoria, additional, Salehi, Tania, additional, Lim, Wai, additional, Boudville, Neil, additional, Chakera, Aron, additional, Chan, Doris, additional, Krishnan, Anoushka, additional, Eqbal, Yusuf, additional, Gillies, Alastair, additional, Vilayur, Eswari, additional, Maung Myint, Thida Maung, additional, Gray, Nicholas, additional, Cheetham, Melissa, additional, Pollock, Carol, additional, Cooper, Bruce, additional, Mather, Amanda, additional, Roxburgh, Sarah, additional, Shen, Yvonne, additional, Stangenberg, Stefanie, additional, Siriwardana, Amanda, additional, O'Lone, Emma, additional, Wan, Susan, additional, Neuen, Brendon, additional, Tsun Kit Ha, Jeffrey, additional, Kim, Dana, additional, Heath, Lauren, additional, Jain, Arunima, additional, Phua, Elaine, additional, Li, Yan, additional, Gallagher, Martin, additional, Jardine, Meg, additional, Ritchie, Angus, additional, Razavian, Mona, additional, Foote, Celine, additional, Wyndham, Roger, additional, Sen, Shaundeep, additional, Endre, Zoltan, additional, Erlich, Jonathan, additional, Fernando, Mangalee, additional, Yong, Kenneth, additional, Luxton, Grant, additional, Kotwal, Sradha, additional, Roger, Simon, additional, Wijeratne, Vidu, additional, Packham, David, additional, Fraser, Ian, additional, Vandewiele, Bert, additional, Laute, Margo, additional, Lemahieu, Wim, additional, Jamar, Sofie, additional, Ombelet, Sara, additional, Meeus, Gert, additional, Decupere, Marc, additional, Schockaert, Olivier, additional, Doubel, Peter, additional, Viaene, Liesbeth, additional, Radermacher, Luc, additional, Masset, Catherine, additional, Moonen, Martial, additional, Firre, Eric, additional, Milicevic, Martina, additional, Warling, Xavier, additional, Vanacker, An, additional, Malfait, Thomas, additional, Durlen, Ivan, additional, Horvatic, Ivica, additional, Savuk, Ana, additional, Gellineo, Lana, additional, Karanovic, Sandra, additional, Dika, Zivka, additional, Plavljanic, Djuro, additional, Mikacic, Ivana, additional, Trajbar Kentric, Dubravka, additional, Barisic, Dunja, additional, Stankovic, Marija, additional, Majstorovic Barac, Karolina, additional, Kruljac, Ivan, additional, Pavlovic, Drasko, additional, Drinkovic, Martin, additional, Prkacin, Ingrid, additional, Barbic, Jerko, additional, Sitas, Zvonimir, additional, Vujcic, Dunja, additional, Rychlik, Ivan, additional, Benesova, Anna, additional, Drinovska, Klara, additional, Kratka, Karolina, additional, Maixnerova, Dita, additional, Ilmoja, Madis, additional, Unt, Kristin, additional, Lilienthal, Kadri, additional, Auerbach, Asta, additional, Leis, Liisi, additional, Piel, Julia, additional, Adoberg, Annika, additional, Kolvald, Kulli, additional, Veermae, Kristi, additional, Telling, Kadri, additional, Seppet, Elviira, additional, Uhlinova, Jana, additional, Zaoui, Philippe, additional, Carron, Pierre-Louis, additional, Masson, Ingrid, additional, Dinic, Miriana, additional, Thibaudin, Damien, additional, Broyet, Christian, additional, Maillard, Nicolas, additional, Mohey, Hesham, additional, Mariat, Christophe, additional, Claisse, Guillaume, additional, Alamartine, Eric, additional, Dussol, Bertrand, additional, Burtey, Stephane, additional, Chiche-Jourde, Noemie, additional, Serre, Jean-Emmanuel, additional, Jeantet, Guillaume, additional, Chenine, Leila, additional, Blanchard, Anne, additional, Roueff, Stephane, additional, Thervet, Eric, additional, Fouassier, David, additional, Buffet, Alexandre, additional, Livrozet, Marine, additional, Gaisset, Roxane, additional, Karras, Alexandre, additional, Heng, Anne-Elisabeth, additional, Garrouste, Cyril, additional, Philipponnet, Carole, additional, Nicolo, Clementine, additional, Atenza, Alba, additional, Lanaret, Camille, additional, Greze, Clarisse, additional, Mayet, Valentin, additional, Dumond, Clement, additional, Delmas, Yahsou, additional, Combe, Christian, additional, Rigothier, Claire, additional, Burguet, Laure, additional, Labat, Aurore, additional, Mucha, Simon, additional, de Précigout, Valérie, additional, Weinreich, Thomas, additional, Reichel, Helmut, additional, Draganova, Diliana, additional, Wolf, Lothar, additional, Hohenstein, Bernd, additional, Heinrichs, Sven, additional, Kulka, Simone, additional, Sat, Sebahat, additional, Weiland, Lea, additional, Krueger, Thilo, additional, Wolf, Gunter, additional, Kettner, Christiane, additional, Schlosser, Mandy, additional, Herfurth, Johann Konstantin, additional, Koch, Annegret, additional, Busch, Martin, additional, Werth, Stephan Christian, additional, Nitschke, Martin, additional, Cakiroglu, Figen, additional, Sarnow, Franziska, additional, Schulz, Lisa, additional, Weiner, Stefan, additional, Wirtz, Nikolaus, additional, Koester, Eric, additional, Moeller, Marcus, additional, Stamellou, Eleni, additional, Sanden, Silja, additional, Schmidt-Guertler, Hans, additional, Bernhardt, Wanja, additional, Patecki, Margret, additional, Schlieper, Georg, additional, Schulte, Kevin, additional, Girardet, Annette, additional, Kunzendorf, Ulrich, additional, Kwan, Lorraine Pui Yuen, additional, Mok, Maggie Ming Yee, additional, Chan, Gary Chi Wang, additional, Ma, Mingyao, additional, Lie, Davina Ngoi Wah, additional, Chan, Anthony Ting Pong, additional, Szeto, Cheuk Chun, additional, Ng, Kit Chung Jack, additional, Cheung, Siu Fai, additional, Yue, Tak Tai Andrew, additional, Fung, Ka Shun Samuel, additional, Tang, Hon, additional, Yim, Ka Fai, additional, Law, Wai Ping, additional, Wong, Yick Hei, additional, Lam, Chi Kwan Darwin, additional, Wong, Sze Ho Sunny, additional, Marcantoni, Carmelita, additional, Aliotta, Roberta, additional, Deodato, Francesca, additional, Patella, Gemma, additional, Comi, Nicolino, additional, Vita, Caterina, additional, Carullo, Nazareno, additional, Bolignano, Davide, additional, Musolino, Michela, additional, Trillini, Matias, additional, Perico, Norberto, additional, Remuzzi, Giuseppe, additional, Daina, Erica, additional, Biancone, Luigi, additional, Colla, Loredana, additional, Burdese, Manuel, additional, Cogno, Chiara, additional, Boaglio, Elena, additional, Abbasciano, Isabella, additional, Zizzi, Carlotta Federica, additional, Randone, Paolo, additional, Napodano, Pietro, additional, Ricchiuto, Anna, additional, Cassia, Matthias, additional, Accarino, Simone, additional, Cozzolino, Mario, additional, Baccaro, Rocco, additional, Costanzi, Stefano, additional, Di Maio, Federica, additional, Arena, Maria, additional, Urciuolo, Federica, additional, Vigano, Sara, additional, Cavalli, Andrea, additional, Limardo, Monica, additional, Bordoli, Monica, additional, Ponti, Serena, additional, Longhi, Selena, additional, Solazzo, Andrea, additional, Giaroni, Francesco, additional, Donati, Gabriele, additional, Torreggiani, Massimo, additional, Catucci, Davide, additional, Colucci, Marco, additional, Esposito, Vittoria, additional, Esposito, Ciro, additional, Gesualdo, Loreto, additional, Capaccio, Flavia, additional, Diletta Stea, Emma, additional, Sivo, Carmen, additional, Annese, Francesca, additional, Papadia, Federica, additional, Messa, Piergiorgio, additional, Belingheri, Mirco, additional, Passerini, Patrizia, additional, Malvica, Silvia, additional, Vickiene, Alvita, additional, Zakauskiene, Urte, additional, Asakiene, Egle, additional, Bumblyte', Inga Arune, additional, Stankuviene, Asta, additional, Santockiene, Lina, additional, Hayat, Ashik, additional, Williams, Allister, additional, Sizeland, Peter, additional, Tan, Eddie, additional, Waters, Gerald, additional, Chan, Lai Wan, additional, Henderson, Andrew, additional, Turnbull, Angus, additional, McNally, Andrew, additional, Reynolds, Annie, additional, Pilmore, Helen, additional, Dittmer, Ian, additional, Manley, Paul, additional, Stallworthy, Elizabeth, additional, Goh, Tze, additional, Semple, David, additional, Collins, Michael, additional, Curry, Elizabeth, additional, Ahmed, Jafar, additional, Nguyen, Thu, additional, Winiarska, Agata, additional, Zbrzezniak, Justyna, additional, Stompor, Tomasz, additional, Krajewska, Magdalena, additional, Augustyniak-Bartosik, Hanna, additional, Zielinska, Dorota, additional, Jander, Anna, additional, Stanczyk, Malgorzata, additional, Tkaczyk, Marcin, additional, Miarka, Przemyslaw, additional, Aksamit, Dariusz, additional, Jaskowski, Piotr, additional, Sulowicz, Wladyslaw, additional, Cieniawski, Dominik, additional, Gontarek-Kacprzak, Julita, additional, Felicjanczuk, Elzbieta, additional, Kwella, Norbert, additional, Kwella, Bogna, additional, Satora, Ewa, additional, Fernandes, João Carlos, additional, Gomes, Ana Marta, additional, Reis, Marina, additional, Lopes, Daniela, additional, Almeida, Catarina, additional, Sá, Helena, additional, Figueiredo, Ana Carolina, additional, Pardinhas, Clara, additional, Almeida, Edgar, additional, Raimundo, Mario, additional, Cortesão Costa, Ana, additional, Falcao Goncalves, Luis Pedro, additional, Fernandes, Sara, additional, Silva, Sónia, additional, Teixeira, Catarina, additional, Fernandes, Adriana, additional, Nolasco, Fernando, additional, Alves, Patricia, additional, Gois, Mario, additional, Fonseca, Nuno, additional, Messias, Ana, additional, Menezes, Maria, additional, Cardoso, Filipa, additional, Sousa, Helena, additional, Marques, Joana, additional, Barata, Rui, additional, Lopes, Jose Antonio, additional, Jorge, Sofia, additional, Gameiro, Joana, additional, de Almeida Agapito Fonseca, Jose Nuno, additional, Goncalves, Sara, additional, Farinha, Ana, additional, Valerio Santos, Patricia, additional, Natario, Ana, additional, de Jesus Barreto, Jose Carlos, additional, Abrantes, Catarina, additional, Quadrado Soares, Elsa Sofia, additional, Soares Felgueiras, Joana de Sousa, additional, Cunha, Liliana, additional, Parreira, Lucia, additional, Furtado, Teresa, additional, Vaz, Alvaro, additional, Oh, Kook-Hwan, additional, Lee, Hajeong, additional, Joong Kim, Se, additional, Jeong, Jong Cheol, additional, Hoon Kim, Yeong, additional, Kim, Yunmi, additional, Park, Hyeong Cheon, additional, Choi, Hoon Young, additional, Wook Kim, Hyung, additional, Lee, Moon Hyoung, additional, Yoon, Songuk, additional, Lee, Kyu-Beck, additional, Hyun, YoungYoul, additional, Yoo, Tae-Hyun, additional, Han, Seung Hyeok, additional, Park, Jung Tak, additional, Kim, Sunggyun, additional, Song, Young Rim, additional, Kim, Jwa-Kyung, additional, Lee, Hyung-seok, additional, Joo, Narae, additional, Lee, JungEun, additional, Ryoun Jang, Hye, additional, Jeon, Junseok, additional, Chung, Wookyung, additional, Lee, HyunHee, additional, Chang, Jae Hyun, additional, Chun, Ka Yeong, additional, Jung, Ji Yong, additional, Ro, Han, additional, Kim, Aejin, additional, Jo, Sang-Kyung, additional, Yang, Jihyun, additional, Kim, Myung-Gyu, additional, Oh, SeWon, additional, Martinez Villanueva, Caridad, additional, Gimeno, Ana Vilar, additional, Andres Useche Bonilla, Gustavo, additional, Tamarit, Esther, additional, Galan Serrano, Antonio, additional, Verde Moreno, Eduardo, additional, Fernandez, Jose Luño, additional, Goicoechea Diezhandino, Maria Angeles, additional, Verdalles Guzman, Ursula, additional, de Jose, Ana Perez, additional, Ortiz Arduan, Alberto, additional, Pérez Gómez, María Vanessa, additional, Martín Cleary, Catalina, additional, Prado, Raul Fernandez, additional, Goma, Elena, additional, Ballarin, Jose, additional, Encarnacion, Montserrat Diaz, additional, Da Silva Santos, Iara, additional, Marco Rusinol, Helena, additional, Furlano, Monica, additional, Arias, Carlos, additional, Barrios, Clara, additional, Garcia, Eva Rodriguez, additional, Sierra Ochoa, Adriana, additional, Vizcaino Castillo, Belen, additional, Pantoja Perez, Jonay, additional, Gonzalez Moya, Mercedes, additional, Sargsyan, Mari, additional, Calatayud Aristoy, Emma, additional, Bernabeu, Ana Avila, additional, Perez Lluna, Leticia, additional, Malek Marin, Tamara, additional, Antonia Munar Vila, Maria, additional, Bobadilla Rico, Ivon Maritza, additional, Allende Burgos, Natalia, additional, Gutierrez Martinez, Eduardo, additional, Gutierrez Solis, Elena, additional, Sevillano, Angel, additional, Merida Herrero, Evangelina, additional, Miquel Blasco Pelicano, Josep, additional, Rodas Marin, Lida Maria, additional, Quintana, Luis F, additional, Antonieta Azancot Rivero, Maria, additional, Ramos Terrades, Natalia, additional, Garcia Carro, Clara, additional, Agraz Pamplona, Irene, additional, Salgueira Lazo, Mercedes, additional, de la Prada Alvarez, Francisco, additional, Alonso Garcia, Fabiola, additional, Adrian Aguilera Morales, Wenceslao, additional, Virxinia Pol Heres, Salia, additional, Forcen, Angel, additional, Parra Moncasi, Eduardo, additional, Medrano Villarroya, Cristina, additional, Soria Villen, Alejandro, additional, Gracia Garcia, Olga, additional, Velo Plaza, Mercedes, additional, Sánchez de la Nieta, Maria Dolores, additional, Calvo Arevalo, Marta, additional, Moreno, Antolina, additional, Cigarran Guldris, Secundino, additional, de Vicente, Manuel Pereira, additional, Munar Vila, Maria Antonia, additional, Hsu, Bang-Gee, additional, Wang, Chih-Hsien, additional, Chen, Cheng-Hsu, additional, Yu, Tung-Min, additional, Wu, Ming-Ju, additional, Tsai, Shang-Feng, additional, Hsu, Chia-Tien, additional, Chiu, Hsien-Fu, additional, Chou, Kang-Ju, additional, Fang, Hua-Chang, additional, Lee, Po-Tsang, additional, Chen, Hsin-Yu, additional, Chen, Chien-Liang, additional, Huang, Chien-Wei, additional, Ou, Shih-Hsiang, additional, Ho, Tzung-Yo, additional, Hsu, Chih-Yang, additional, Chang, Ming-Shan, additional, Chiu, Yen-Ling, additional, Peng, Yu-Sen, additional, Shu, Kai-Hsiang, additional, Pan, Szu-Yu, additional, Hsu, Shih-Ping, additional, Yang, Ju-Yeh, additional, Pai, Mei-Fen, additional, Tseng, Po-Yu, additional, Wu, Hon-Yen, additional, Tsai, Wan-Chuan, additional, Tung, Kuei-Ting, additional, Chen, Hung-Yuan, additional, Chen, Hung-Chun, additional, Kuo, Mei-Chuan, additional, Hwang, Daw-Yang, additional, Chiu, Yi-Wen, additional, Hung, Chi-Chih, additional, Kuo, Hung-Tien, additional, Tsai, Jer-Chia, additional, McCafferty, Kieran, additional, Forbes, Suzanne, additional, Dasgupta, Indranil, additional, Thomas, Mark, additional, Mahdi, Amar, additional, Ajayi, Bamidele, additional, Chowdhury, Paramit, additional, Kasimatis, Theodoros, additional, Moutzouris, Dimitrios, additional, Dudreuilh, Caroline, additional, Pruthi, Rishi, additional, Mansfield, Nick, additional, Doctor, Gabriel, additional, Shah, Sapna, additional, Kon, Sui, additional, Smith, Priscilla, additional, Hamilton, Patrick, additional, Kanigicherla, Durga, additional, Ibrahim Ragy, Omar Sherin, additional, Alchi, Bassam, additional, Flossmann, Oliver, additional, Ghalli, Farid, additional, Lawman, Sarah, additional, Sinha, Smeeta, additional, Chrysochou, Constantina, additional, Chukwu, Chukwuma, additional, Maire De Bhailis, Aine, additional, Al Chalabi, Saif, additional, Hudson, Amy, additional, Gopu, Arun, additional, Wickens, Olivia, additional, Storrar, Joshua, additional, Wahba, Mona, additional, Lorde, Nathan, additional, Rony, Mohammad, additional, Griffin, Sian, additional, Latif, Farah, additional, Ali, Mohammad, additional, DaSilva, Louise, additional, Ayling-Smith, Jonathan, additional, Mahdi, Eamon, additional, Willcocks, Lisa, additional, Jones, Rachel, additional, Cheung, Chee Kay, additional, Selvaskandan, Haresh, additional, Pugh, Dan, additional, Sayer, Matthew, additional, Dhaun, Neeraj, additional, Chapman, Fiona, additional, Mark, Patrick, additional, Geddes, Colin, additional, McQuarrie, Emily, additional, Patel, Rajan, additional, Solomon, Laurence, additional, Ponnusamy, Arvind, additional, Morris, Adam, additional, Okoh, Pedro, additional, Floyd, Lauren, additional, Dhaygude, Ajay, additional, Leung, Janson, additional, Goldsmith, Christopher, additional, Pandya, Bhavna, additional, Tez, Didem, additional, Mikhail, Ashraf, additional, Brown, Karen, additional, Bucknall, Thomas, additional, Lambie, Mark, additional, Comunale, Roderick, additional, Brandon, Donald, additional, Martinez, Stacy, additional, Hall, Amanda, additional, Henderson, Amy, additional, Fearday, Aaron, additional, Douthit, Nicole, additional, Snow, Brian, additional, Silva, Arnold, additional, Sly, Cathylee, additional, Keller, Christopher, additional, Davidson, Robert, additional, Meng, Jerry, additional, Haws, Robert, additional, Kattamanchi, Siddhartha, additional, Mojarrab, Javad, additional, Pillai, Unnikrishnan, additional, Lafayette, Richard, additional, O'Shaughnessy, Michelle, additional, Kamal, Fahameedah, additional, Mehta, Kshama, additional, Baker, Bruce, additional, Ruiz, Mario, additional, Jyothinagaram, Praveena, additional, Peri, Usha, additional, Paxton, William, additional, Tumlin, James, additional, McGreal, Kerri, additional, McCarthy, Ellen, additional, Kimber, Cassandra, additional, Gautam, Archana, additional, Khalil, Kassem, additional, Nguyen, Viet, additional, Minasian, Raffi, additional, Arfaania, Dariush, additional, Daneshvari, Sam, additional, Zakari, Michel, additional, Patrikyan, Artashes, additional, Afsari, Rouzbeh, additional, Ayvazyan, Christine, additional, Fakih, Faisal, additional, Lagatta, Mark, additional, Rodriguez, Alfred, additional, Avella, Jorge Enrique Monroy, additional, Patak, Ramachandra, additional, Kadakia, Jigar, additional, Appel, Gerald, additional, Ahn, Wooin, additional, Nelson, Bradley, additional, Medina, Allyson, additional, Ahmad, Syeda, additional, Peleg, Yonatan, additional, Clement, Nisha, additional, Chiu, Ian, additional, Hendren, Elizabeth, additional, Bomback, Andrew, additional, Canetta, Pietro, additional, Spinowitz, Bruce, additional, Charytan, Chaim, additional, Parikh, Nishita, additional, Kuo, Sheng, additional, Raichoudhury, Ritesh, additional, Dobre, Mirela, additional, Negrea, Lavinia, additional, Padiyar, Aparna, additional, Jittirat, Arksarapuk, additional, Pradhan, Nishigandha, additional, Dhelaria, Ranjit, additional, Balamuthusamy, Saravanan, additional, Madhrira, Machaiah, additional, Powell, Thomas, additional, Lifland, Howard, additional, Bailey, Asha, additional, Ford Sightler, Sarah Ashley, additional, Suthar, Meera Patel, additional, Green, Heather, additional, Parikh, Samir, additional, Ayoub, Isabelle, additional, Almaani, Salem, additional, Contreras, Gabriel, additional, Fornoni, Alessia, additional, Drexler, Yelena, additional, Geara, Abdallah, additional, Sheridan, Brittany, additional, Coppock, Gaia, additional, Hogan, Jonathan, additional, Gonzalez, Carlos, additional, Bhadra, Shamik, additional, Chowdhury, Pradip, additional, Kyaw, Kay, additional, Tan, May, additional, Raakesh, Lathika, additional, Mendoza, Elder, additional, Viramontes, Veronica, additional, Chaudhry, Asghar, additional, Carbonell, Juan, additional, Gadh, Rajdeep, additional, Fernandez, Victor, additional, Kassem, Mohamad, additional, Jacob, Radu, additional, Wilder, Karen, additional, Newsome, Britt, additional, Klamm, Kathryn, additional, Suyumova, Irina, additional, Kooienga, Laura Ann, additional, Janko, Catherine, additional, Rizk, Dana, additional, Julian, Bruce, additional, Caster, Dawn, additional, Perez, Erika, additional, Garg, Gunjan, additional, Gowda, Nayan, additional, Udani, Suneel, additional, Mandayam, Sreedhar, additional, Workeneh, Biruh, additional, Assefi, Ali, additional, Greco, Barbara, additional, Germain, Michael, additional, Patel, Jusmin, additional, Quinn, Sarah, additional, Sullivan, James, additional, Glaze, Jeffrey, additional, Madonia, Phillip, additional, McMahon, Kellyn, additional, Giles, Harold, additional, Adler, Sharon, additional, and Dai, Tiane, additional

Published
2023
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12. Daclatasvir for previously untreated chronic hepatitis C genotype-1 infection: a randomised, parallel-group, double-blind, placebo-controlled, dose-finding, phase 2a trial

Author

Pol, Stanislas, Ghalib, Reem H, Rustgi, Vinod K, Martorell, Claudia, Everson, Greg T, Tatum, Harvey A, Hézode, Christophe, Lim, Joseph K, Bronowicki, Jean-Pierre, Abrams, Gary A, Bräu, Norbert, Morris, David W, Thuluvath, Paul J, Reindollar, Robert W, Yin, Philip D, Diva, Ulysses, Hindes, Robert, McPhee, Fiona, Hernandez, Dennis, Wind-Rotolo, Megan, Hughes, Eric A, and Schnittman, Steven

Published
2012
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16. Supplemental Material, JCPT_Oct_2016_225_revised_CV_effect_revised_supplemental_materials_24_Jan_2018 - Cardiovascular Safety of the Selective μ-Opioid Receptor Antagonist Naloxegol: A Novel Therapy for Opioid-Induced Constipation

Author

White, William B., Kowey, Peter, Diva, Ulysses, Sostek, Mark, and Tummala, Raj

Subjects
110203 Respiratory Diseases, FOS: Clinical medicine, Cardiology, 110323 Surgery, 110306 Endocrinology, humanities, 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
Abstract

Supplementary Material, JCPT_Oct_2016_225_revised_CV_effect_revised_supplemental_materials_24_Jan_2018 for Cardiovascular Safety of the Selective μ-Opioid Receptor Antagonist Naloxegol: A Novel Therapy for Opioid-Induced Constipation by William B. White, Peter Kowey, Ulysses Diva, Mark Sostek, and Raj Tummala in Journal of Cardiovascular Pharmacology and Therapeutics

Published
2018
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19. Musculoskeletal disorders of the neck and shoulder in dental hygienists and dental hygiene students

Author

Morse, Tim, Bruneau, Heather, Michalak-Turcotte, Claudia, Sanders, Martha, Warren, Nicholas, Dussetschleger, Jeff, Diva, Ulysses, Croteau, Marc, and Cherniack, Martin

Subjects
Analysis, Risk factors, Health aspects, Ergonomic aid, Ergonomics, Students -- Health aspects -- Analysis, Ergonomics -- Health aspects -- Analysis, Oral hygiene -- Analysis -- Health aspects, Mouth -- Care and treatment, Dental care -- Analysis -- Health aspects, Dental hygiene -- Analysis -- Health aspects
Abstract

Introduction High rates of occurrence of upper extremity musculoskeletal disorders (MSDs) in dental professionals (dentist, dental hygienist, and dental assistant) are well documented, including regional neck and shoulder pain, shoulder [...], Purpose. Dental hygienists have been found to have high rates of neck and shoulder disorders, but there is very limited information on risk factors associated with those disorders, the level of risk for students, and the relationship of prior work as dental assistants for dental hygiene students. This study examines self-reported and physician-diagnosed neck and shoulder pain. Methods. A cohort consisting of 27 dental hygiene students with no prior dental occupation experience (mean age 24, 6.2 SD), and 39 dental hygiene students with prior experience as dental assistants (mean age 28, 6.0) and 94 experienced dental hygienists (mean age 46, 8.8) completed a questionnaire on risk factors and self reported pain, and were examined by a physician in reference to upper extremity findings and diagnoses. Analysis included tabular, trend, and logistic regression analysis. Results. There were significant differences for risks, symptoms, and physician findings. Risk factors had a stepwise progression for students, student/assistants, and experienced dental hygienists, including working with a bent neck often or very often (79%, 89%, 96%, respectively, p Conclusion. Risk factors and both self-reported and physician-diagnosed neck and shoulder symptoms increase in frequency from students to experienced hygienists, and students have higher prevalence if they are also dental assistants. Keywords: Ergonomics, cumulative trauma disorders, musculoskeletal disorders, dental hygienists, dental assistants, risk factors, neck and shoulder disorders

Published
2007

21. Treatment with Naloxegol Versus Placebo: Pain Assessment in Patients with Noncancer Pain and Opioid‐Induced Constipation.

Author

Webster, Lynn, Diva, Ulysses, Tummala, Raj, and Sostek, Mark

Subjects
*THERAPEUTIC use of narcotics, *CHRONIC pain, *CONSTIPATION, *MORPHINE, *NARCOTICS, *ORAL drug administration, *PAIN measurement, *RANDOMIZED controlled trials, *TREATMENT effectiveness, *BLIND experiment, *DESCRIPTIVE statistics, *ADULTS
Abstract

Abstract: Objective: To summarize results from pain and opioid use assessments with naloxegol in adults with opioid‐induced constipation (OIC) and chronic noncancer pain. Methods: Two phase 3 randomized, double‐blind, 12‐week studies evaluated the efficacy and safety of oral naloxegol (12.5 or 25 mg daily) in adults (18 to < 85 years) with confirmed OIC and chronic noncancer pain: KODIAC‐04 (NCT01309841) and KODIAC‐05 (NCT01323790). Pain level was assessed daily (11‐point numeric rating scale [NRS]; 0 = no pain, 10 = worst imaginable pain). Changes from baseline in mean weekly pain scores and opioid dose (weeks 1 through 12) were analyzed using mixed‐model repeated measures. Results: At baseline, mean daily NRS average pain scores ranged from 4.5 to 4.8 for all groups in KODIAC‐04 (N = 652) and were 4.6 for each group in KODIAC‐05 (N = 700). Respective mean ± SD changes from baseline average pain for placebo, naloxegol 12.5 mg, and naloxegol 25 mg were −0.2 ± 1.07, −0.3 ± 1.05 (P = 0.773 vs. placebo), and 0.2 ± 0.95 (P = 0.837 vs. placebo; KODIAC‐04) and −0.1 ± 0.94, −0.1 ± 0.87 (P = 0.744), and 0.0 ± 1.18 (P = 0.572; KODIAC‐05). At baseline, mean daily opioid doses ranged from 135.6 to 143.2 morphine equivalent units (MEUs)/day in KODIAC‐04, and from 119.9 to 151.7 MEUs/day in KODIAC‐05. Respective mean ± SD changes from baseline dose were −1.8 ± 30.19, −2.3 ± 20.52 (P = 0.724 vs. placebo), and 0.4 ± 13.01 (P = 0.188 vs. placebo; KODIAC‐04) and −0.3 ± 17.14, −1.3 ± 17.11 (P = 0.669 vs. placebo), and 0.1 ± 8.54 (P = 0.863 vs. placebo; KODIAC‐05). Changes in maintenance opioid dose were few; reasons for such changes were similar across treatment groups. Conclusion: Centrally mediated opioid analgesia was maintained during treatment with naloxegol in patients with noncancer pain and OIC. [ABSTRACT FROM AUTHOR]

Published
2018
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24. The effect warming methods on sensory nerve coduction velocity in shipyard workers occupationally exposed to hand-arm vibration

Author

Chernicak, Martin, Brammer, Anthony J., Lundström, Ronnie, Morse, Tim F., Neely, Greg, Nilsson, Thor, Peterson, Donald, Toppila, Esk, Warren, Nicholas, Diva, Ulysses, Croteau, Marc, Dussetschleger, Jeffrey, Chernicak, Martin, Brammer, Anthony J., Lundström, Ronnie, Morse, Tim F., Neely, Greg, Nilsson, Thor, Peterson, Donald, Toppila, Esk, Warren, Nicholas, Diva, Ulysses, Croteau, Marc, and Dussetschleger, Jeffrey

Published
2008

25. W1805 Entecavir Maintains a High Genetic Barrier to HBV Resistance Through 6 Years in NaïVE Patients

Author

Tenney, Daniel J., primary, Pokornowski, Kevin A., additional, Rose, Ronald E., additional, Baldick, Carl J., additional, Eggers, Betsy J., additional, Fang, Jie, additional, Wichroski, Michael J., additional, Diva, Ulysses A., additional, Xu, Dong, additional, Wilber, Richard B., additional, Brett-Smith, Helena, additional, and Iloeje, Uchenna H., additional

Published
2009
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26. Early hepatitis B virus DNA reduction in hepatitis B e antigen-positive patients with chronic hepatitis B: A randomized international study of entecavir versus adefovir

Author

Leung, Nancy, primary, Peng, Cheng-Yuan, additional, Hann, Hie-Won, additional, Sollano, Jose, additional, Lao-Tan, Judy, additional, Hsu, Chao-Wei, additional, Lesmana, Laurentius, additional, Yuen, Man-Fung, additional, Jeffers, Lennox, additional, Sherman, Morris, additional, Min, Albert, additional, Mencarini, Kimberly, additional, Diva, Ulysses, additional, Cross, Anne, additional, Wilber, Richard, additional, and Lopez-Talavera, Juan, additional

Published
2008
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28. Syndromes from segmental vibration and nerve entrapment: observations on case definitions for carpal tunnel syndrome

Author

Cherniack, Martin, primary, Brammer, Anthony J., additional, Lundstrom, Ronnie, additional, Morse, Tim F., additional, Neely, Greg, additional, Nilsson, Tohr, additional, Peterson, Donald, additional, Toppila, Esko, additional, Warren, Nicholas, additional, Diva, Ulysses, additional, Croteau, Marc, additional, and Dussetschleger, Jeffrey, additional

Published
2007
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31. Sparsentan versus Irbesartan in Focal Segmental Glomerulosclerosis.

Author

Rheault MN, Alpers CE, Barratt J, Bieler S, Canetta P, Chae DW, Coppock G, Diva U, Gesualdo L, Heerspink HJL, Inrig JK, Kirsztajn GM, Kohan D, Komers R, Kooienga LA, Lieberman K, Mercer A, Noronha IL, Perkovic V, Radhakrishnan J, Rote W, Rovin B, Tesar V, Trimarchi H, Tumlin J, Wong MG, and Trachtman H

Subjects
Humans, Biomarkers, Creatinine, Glomerular Filtration Rate, Child, Adolescent, Young Adult, Adult, Middle Aged, Aged, Remission Induction, Glomerulosclerosis, Focal Segmental complications, Glomerulosclerosis, Focal Segmental drug therapy, Glomerulosclerosis, Focal Segmental physiopathology, Irbesartan administration & dosage, Irbesartan adverse effects, Irbesartan therapeutic use, Proteinuria drug therapy, Proteinuria etiology
Abstract

Background: An unmet need exists for focal segmental glomerulosclerosis (FSGS) treatment. In an 8-week, phase 2 trial, sparsentan, a dual endothelin-angiotensin receptor antagonist, reduced proteinuria in patients with FSGS. The efficacy and safety of longer-term treatment with sparsentan for FSGS are unknown., Methods: In this phase 3 trial, we enrolled patients with FSGS (without known secondary causes) who were 8 to 75 years of age; patients were randomly assigned to receive sparsentan or irbesartan (active control) for 108 weeks. The surrogate efficacy end point assessed at the prespecified interim analysis at 36 weeks was the FSGS partial remission of proteinuria end point (defined as a urinary protein-to-creatinine ratio of ≤1.5 [with protein and creatinine both measured in grams] and a >40% reduction in the ratio from baseline). The primary efficacy end point was the estimated glomerular filtration rate (eGFR) slope at the time of the final analysis. The change in eGFR from baseline to 4 weeks after the end of treatment (week 112) was a secondary end point. Safety was also evaluated., Results: A total of 371 patients underwent randomization: 184 were assigned to receive sparsentan and 187 to receive irbesartan. At 36 weeks, the percentage of patients with partial remission of proteinuria was 42.0% in the sparsentan group and 26.0% in the irbesartan group (P = 0.009), a response that was sustained through 108 weeks. At the time of the final analysis at week 108, there were no significant between-group differences in the eGFR slope; the between-group difference in total slope (day 1 to week 108) was 0.3 ml per minute per 1.73 m 2 of body-surface area per year (95% confidence interval [CI], -1.7 to 2.4), and the between-group difference in the slope from week 6 to week 108 (i.e., chronic slope) was 0.9 ml per minute per 1.73 m 2 per year (95% CI, -1.3 to 3.0). The mean change in eGFR from baseline to week 112 was -10.4 ml per minute per 1.73 m 2 with sparsentan and -12.1 ml per minute per 1.73 m 2 with irbesartan (difference, 1.8 ml per minute per 1.73 m 2 ; 95% CI, -1.4 to 4.9). Sparsentan and irbesartan had similar safety profiles, and the frequency of adverse events was similar in the two groups., Conclusions: Among patients with FSGS, there were no significant between-group differences in eGFR slope at 108 weeks, despite a greater reduction in proteinuria with sparsentan than with irbesartan. (Funded by Travere Therapeutics; DUPLEX ClinicalTrials.gov number, NCT03493685.)., (Copyright © 2023 Massachusetts Medical Society.)

Published
2023
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32. A 12-week extension study to assess the safety and tolerability of naloxegol in patients with noncancer pain and opioid-induced constipation.

Author

Webster L, Tummala R, Diva U, and Lappalainen J

Subjects
Administration, Oral, Aged, Double-Blind Method, Female, Humans, Male, Middle Aged, Prospective Studies, United States, Analgesics, Opioid adverse effects, Analgesics, Opioid therapeutic use, Constipation chemically induced, Morphinans adverse effects, Morphinans therapeutic use, Narcotic Antagonists adverse effects, Narcotic Antagonists therapeutic use, Pain drug therapy, Polyethylene Glycols adverse effects, Polyethylene Glycols therapeutic use
Abstract

Objective: To compare the long-term safety and tolerability of naloxegol with placebo in patients with opioid-induced constipation (OIC) and noncancer pain., Design: Twelve-week, multicenter, randomized, double-blind, parallel-group phase 3 extension study (KODIAC-07, NCT01395524)., Setting: Clinical investigation centers in the United States., Patients: Adult outpatients (N = 302) with confirmed OIC who had completed a 12-week pivotal phase 3 study (KODIAC-04, NCT01309841)., Interventions: Daily oral administration of naloxegol (12.5 and 25 mg) or placebo., Main Outcome Measures: Adverse events (AEs), including treatment-related AEs, serious AEs, and AEs of special interest; changes from baseline to week 12 in pain scores, daily opioid dose, and symptoms and quality-of-life measurements., Results: No important new AEs occurred during this extension study compared with KODIAC-04. AEs occurred more frequently with naloxegol 25 mg (41.2 percent) versus naloxegol 12.5 mg (34.0 percent) and placebo (33.0 percent). Treatment-emergent AEs occurring in >5 percent of patients in either naloxegol group during the treatment period were arthralgia (25 mg; 5.2 percent) and diarrhea (12.5 mg; 5.3 percent); two reported AEs attributable to opioid withdrawal syndrome in naloxegol groups were deemed unrelated to study medication. None of the gastrointestinal serious AEs was adjudicated as bowel perforation; one patient (naloxegol 12.5 mg) had an event adjudicated as a major cardiovascular event and was unrelated to study medication. Pain scores and daily opioid dose were unchanged, and improvements in symptoms and quality-of-life observed in KODIAC-04 were maintained throughout the extension study., Conclusion: Naloxegol was generally safe and well tolerated in this 12-week extension study in patients with noncancer pain and OIC.

Published
2016
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33. A population based survey of ergonomic risk factors in Connecticut: distribution by industry, occupation, and demographics.

Author

Morse TF, Warren N, Dillon C, and Diva U

Subjects
Age Distribution, Connecticut epidemiology, Health Surveys, Humans, Industry, Musculoskeletal Diseases epidemiology, Occupational Diseases epidemiology, Occupations, Risk Factors, Sex Distribution, Ergonomics, Musculoskeletal Diseases prevention & control, Occupational Diseases prevention & control
Abstract

Background: Risk factors for upper-extremity musculoskeletal disorders (MSD) include biomechanical factors (force, repetition, posture) and psychosocial factors (job stress). A population-based telephone survey of workers in Connecticut characterized these risk factors by industry, occupation, gender, and age., Findings: Risk factors were highly prevalent in the Connecticut workplace, but varied considerably by industry, occupation, gender, and age. Risk factors clustered based on (a) physically active occupations/industries (pushing/pulling, reaching, bent wrists, and tool use), (b) physically passive occupations/industries (static postures, stress, and computer use), and (c) repetitive motion exposures. Physically active patterns had the highest prevalence in construction/agriculture/mining, followed by (in order) wholesale/retail trade, utilities, manufacturing, services, government, and finance/insurance. Physically passive patterns tended to reverse this order, and repetitive motion followed a third pattern. Physically active risk factors were typically higher for males, though this varied by industry and occupation. All risk factors except for stress show a steady decrease with age., Conclusion: Almost 1,000,000 Connecticut workers are estimated to be exposed to repetitive work, bent wrists, and job stress. Workers in high exposure industries and occupations should be closely evaluated for risks, with outreach to industries for preventive ergonomic interventions as preferred to treatment for conditions that arise.

Published
2007

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