Search

Your search keyword '"Do, Lien Anh Ha"' showing total 172 results
Start Over Author "Do, Lien Anh Ha"
172 results on '"Do, Lien Anh Ha"'

2. Impact of pneumococcal conjugate vaccine 13 introduction on severe lower respiratory tract infections associated with respiratory syncytial virus or influenza virus in hospitalized children in Ulaanbaatar, Mongolia

Author

Do, Lien Anh Ha, Tsedenbal, Naranzul, Khishigmunkh, Chimidregzen, Tserendulam, Bazarkhuu, Altanbumba, Lkhagvadorj, Luvsantseren, Dashtseren, Ulziibayar, Munkhchuluun, Suuri, Bujinlkham, Narangerel, Dorj, Tsolmon, Bilegtsaikhan, Demberelsuren, Sodbayar, Nguyen, Cattram, Mungun, Tuya, von Mollendorf, Claire, Badarch, Darmaa, and Mulholland, Kim

Published
2024
Full Text
View/download PDF

3. Differential anti-viral response to respiratory syncytial virus A in preterm and term infants

Author

Anderson, Jeremy, Imran, Samira, Ng, Yan Yung, Wang, Tongtong, Ashley, Sarah, Minh Thang, Cao, Quang Thanh, Le, Thi Trang Dai, Vo, Van Thanh, Phan, Thi Hong Nhu, Bui, Ngoc Xuan Trang, Do, Thi Phuong Trinh, Phan, Thanh Binh, Le, Thuong Vu, Nguyen, Trong Toan, Nguyen, Novakovic, Boris, Tang, Mimi L.K., Wurzel, Danielle, Mulholland, Kim, Pellicci, Daniel G., Do, Lien Anh Ha, and Licciardi, Paul V.

Published
2024
Full Text
View/download PDF

6. Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in children younger than 5 years in 2019: a systematic analysis

Author

Abram, Michael, Aerssens, Jeroen, Alafaci, Annette, Balmaseda, Angel, Bandeira, Teresa, Barr, Ian, Batinović, Ena, Beutels, Philippe, Bhiman, Jinal, Blyth, Christopher C, Bont, Louis, Bressler, Sara S, Cohen, Cheryl, Cohen, Rachel, Costa, Anna-Maria, Crow, Rowena, Daley, Andrew, Dang, Duc-Anh, Demont, Clarisse, Desnoyers, Christine, Díez-Domingo, Javier, Divarathna, Maduja, du Plessis, Mignon, Edgoose, Madeleine, Ferolla, Fausto Martín, Fischer, Thea K, Gebremedhin, Amanuel, Giaquinto, Carlo, Gillet, Yves, Hernandez, Roger, Horvat, Come, Javouhey, Etienne, Karseladze, Irakli, Kubale, John, Kumar, Rakesh, Lina, Bruno, Lucion, Florencia, MacGinty, Rae, Martinon-Torres, Federico, McMinn, Alissa, Meijer, Adam, Milić, Petra, Morel, Adrian, Mulholland, Kim, Mungun, Tuya, Murunga, Nickson, Newbern, Claire, Nicol, Mark P, Odoom, John Kofi, Openshaw, Peter, Ploin, Dominique, Polack, Fernando P, Pollard, Andrew J, Prasad, Namrata, Puig-Barberà, Joan, Reiche, Janine, Reyes, Noelia, Rizkalla, Bishoy, Satao, Shilpa, Shi, Ting, Sistla, Sujatha, Snape, Matthew, Song, Yanran, Soto, Giselle, Tavakoli, Forough, Toizumi, Michiko, Tsedenbal, Naranzul, van den Berge, Maarten, Vernhes, Charlotte, von Mollendorf, Claire, Walaza, Sibongile, Walker, Gregory, Li, You, Wang, Xin, Blau, Dianna M, Caballero, Mauricio T, Feikin, Daniel R, Gill, Christopher J, Madhi, Shabir A, Omer, Saad B, Simões, Eric A F, Campbell, Harry, Pariente, Ana Bermejo, Bardach, Darmaa, Bassat, Quique, Casalegno, Jean-Sebastien, Chakhunashvili, Giorgi, Crawford, Nigel, Danilenko, Daria, Do, Lien Anh Ha, Echavarria, Marcela, Gentile, Angela, Gordon, Aubree, Heikkinen, Terho, Huang, Q Sue, Jullien, Sophie, Krishnan, Anand, Lopez, Eduardo Luis, Markić, Joško, Mira-Iglesias, Ainara, Moore, Hannah C, Moyes, Jocelyn, Mwananyanda, Lawrence, Nokes, D James, Noordeen, Faseeha, Obodai, Evangeline, Palani, Nandhini, Romero, Candice, Salimi, Vahid, Satav, Ashish, Seo, Euri, Shchomak, Zakhar, Singleton, Rosalyn, Stolyarov, Kirill, Stoszek, Sonia K, von Gottberg, Anne, Wurzel, Danielle, Yoshida, Lay-Myint, Yung, Chee Fu, Zar, Heather J, and Nair, Harish

Published
2022
Full Text
View/download PDF

9. Humoral and cellular immune responses in vaccinated and unvaccinated children following SARS‐CoV‐2 Omicron infection.

Author

Toh, Zheng Quan, Anderson, Jeremy, Mazarakis, Nadia, Quah, Leanne, Nguyen, Jill, Higgins, Rachel A, Do, Lien Anh Ha, Ng, Yan Yung, Jalali, Sedi, Neeland, Melanie R, McMinn, Alissa, Saffery, Richard, McNab, Sarah, McVernon, Jodie, Marcato, Adrian, Burgner, David P, Curtis, Nigel, Steer, Andrew C, Mulholland, Kim, and Pellicci, Daniel G

Subjects
VACCINATION of children, SARS-CoV-2 Omicron variant, IMMUNOLOGIC memory, IMMUNE response, ANTIBODY formation
Abstract

Objectives: The immune response in children elicited by SARS‐CoV‐2 Omicron infection alone or in combination with COVID‐19 vaccination (hybrid immunity) is poorly understood. We examined the humoral and cellular immune response following SARS‐CoV‐2 Omicron infection in unvaccinated children and children who were previously vaccinated with COVID‐19 mRNA vaccine. Methods: Participants were recruited as part of a household cohort study conducted during the Omicron predominant wave (Jan to July 2022) in Victoria, Australia. Blood samples were collected at 1, 3, 6 and 12 months following COVID‐19 diagnosis. Humoral immune responses to SARS‐CoV‐2 Spike proteins from Wuhan, Omicron BA.1, BA.4/5 and JN.1, as well as cellular immune responses to Wuhan and BA.1 were assessed. Results: A total of 43 children and 113 samples were included in the analysis. Following Omicron infection, unvaccinated children generated low antibody responses but elicited Spike‐specific CD4 and CD8 T‐cell responses. In contrast, vaccinated children infected with the Omicron variant mounted robust humoral and cellular immune responses to both ancestral strain and Omicron subvariants. Hybrid immunity persisted for at least 6 months post infection, with cellular immune memory characterised by the generation of Spike‐specific polyfunctional CD8 T‐cell responses. Conclusion: SARS‐CoV‐2 hybrid immunity in children is characterised by persisting SARS‐CoV‐2 antibodies and robust CD4 and CD8 T‐cell activation and polyfunctional responses. Our findings contribute to understanding hybrid immunity in children and may have implications regarding COVID‐19 vaccination and SARS‐CoV‐2 re‐infections. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

10. Impact of pneumococcal conjugate vaccine 13 (PCV13) introduction on severe lower respiratory tract infections associated with respiratory syncytial virus or influenza virus in hospitalised children in Ulaanbaatar, Mongolia.

Author

Do, Lien Anh Ha, primary, Tsedenbal, Naranzul, additional, Khishigmunkh, Chimidregzen, additional, Tserendulam, Bazarkhuu, additional, Altanbumba, Lkhagvadorj, additional, Luvsantseren, Dashtseren, additional, Ulziibayar, Munkhchuluun, additional, Suuri, Bujinlkham, additional, Narangerel, Dorj, additional, Tsolmon, Bilegtsaikhan, additional, Demberelsuren, Sodbayar, additional, Nguyen, Cattram, additional, Mungun, Tuya, additional, von Mollendorf, Claire, additional, Badarch, Darmaa, additional, and Mulholland, Kim, additional

Published
2024
Full Text
View/download PDF

11. A case report describing the immune response of an infant with congenital heart disease and severe COVID-19

Author

Wurzel, Danielle, Neeland, Melanie R., Anderson, Jeremy, Abo, Yara-Natalie, Do, Lien Anh Ha, Donato, Celeste M., Bines, Julie E., Toh, Zheng Quan, Higgins, Rachel A., Jalali, Sedi, Cole, Theresa, Subbarao, Kanta, McMinn, Alissa, Dohle, Kate, Haeusler, Gabrielle M., McNab, Sarah, Alafaci, Annette, Overmars, Isabella, Clifford, Vanessa, Lee, Lai-yang, Daley, Andrew J., Buttery, Jim, Bryant, Penelope A., Burgner, David, Steer, Andrew, Tosif, Shidan, Konstantinov, Igor E., Duke, Trevor, Licciardi, Paul V., Pellicci, Daniel G., and Crawford, Nigel W.

Published
2021
Full Text
View/download PDF

12. Evaluation of the impact of childhood 13-valent pneumococcal conjugate vaccine introduction on adult pneumonia in Ulaanbaatar, Mongolia: study protocol for an observational study

Author

von Mollendorf, Claire, Ulziibayar, Mukhchuluun, Gessner, Bradford D., Do, Lien Anh Ha, Nguyen, Cattram D., Beavon, Rohini, Suuri, Bujinlkham, Luvsantseren, Dashtseren, Narangerel, Dorj, Jenney, Adam, Dunne, Eileen M., Satzke, Catherine, Darmaa, Badarchiin, Mungun, Tuya, and Mulholland, E. Kim

Published
2021
Full Text
View/download PDF

13. Global patterns in monthly activity of influenza virus, respiratory syncytial virus, parainfluenza virus, and metapneumovirus: a systematic analysis

Author

Acacio, Sozinho, Alonso, Wladimir J, Antonio, Martin, Ayora Talavera, Guadalupe, Badarch, Darmaa, Baillie, Vicky L, Barrera-Badillo, Gisela, Bigogo, Godfrey, Broor, Shobha, Bruden, Dana, Buchy, Philippe, Byass, Peter, Chipeta, James, Clara, Wilfrido, Dang, Duc-Anh, de Freitas Lázaro Emediato, Carla Cecília, de Jong, Menno, Díaz-Quiñonez, José Alberto, Do, Lien Anh Ha, Fasce, Rodrigo A, Feng, Luzhao, Ferson, Mark J, Gentile, Angela, Gessner, Bradford D, Goswami, Doli, Goyet, Sophie, Grijalva, Carlos G, Halasa, Natasha, Hellferscee, Orienka, Hessong, Danielle, Homaira, Nusrat, Jara, Jorge, Kahn, Kathleen, Khuri-Bulos, Najwa, Kotloff, Karen L, Lanata, Claudio F, Lopez, Olga, Lopez Bolaños, Maria Renee, Lucero, Marilla G, Lucion, Florencia, Lupisan, Socorro P, Madhi, Shabir A, Mekgoe, Omphile, Moraleda, Cinta, Moyes, Jocelyn, Mulholland, Kim, Munywoki, Patrick K, Naby, Fathima, Nguyen, Thanh Hung, Nicol, Mark P, Nokes, D James, Noyola, Daniel E, Onozuka, Daisuke, Palani, Nandhini, Poovorawan, Yong, Rahman, Mustafizur, Ramaekers, Kaat, Romero, Candice, Schlaudecker, Elizabeth P, Schweiger, Brunhilde, Seidenberg, Phil, Simoes, Eric A F, Singleton, Rosalyn, Sistla, Sujatha, Sturm-Ramirez, Katharine, Suntronwong, Nungruthai, Sutanto, Agustinus, Tapia, Milagritos D, Thamthitiwat, Somsak, Thongpan, Ilada, Tillekeratne, Gayani, Tinoco, Yeny O, Treurnicht, Florette K, Turner, Claudia, Turner, Paul, van Doorn, Rogier, Van Ranst, Marc, Visseaux, Benoit, Waicharoen, Sunthareeya, Wang, Jianwei, Yoshida, Lay-Myint, Zar, Heather J, Li, You, Reeves, Rachel M, Wang, Xin, Bassat, Quique, Brooks, W Abdullah, Cohen, Cheryl, Moore, David P, Nunes, Marta, Rath, Barbara, Campbell, Harry, and Nair, Harish

Published
2019
Full Text
View/download PDF

14. Persistence of SARS-CoV-2--Specific IgG in Children 6 Months After Infection, Australia

Author

Toh, Zheng Quan, Higgins, Rachel A., Do, Lien Anh Ha, Rautenbacher, Karin, Mordant, Francesca L., Subbarao, Kanta, Dohle, Kate, Nguyen, Jill, Steer, Andrew C., Tosif, Shidan, Crawford, Nigel W., Mulholland, Kim, and Licciardi, Paul V.

Subjects
Immune response -- Health aspects, Immunoglobulin G -- Health aspects, Pediatric research, Health
Abstract

The duration of the humoral immune response in children infected with severe acute respiratory syndrome coronavirus 2 is unknown. We detected specific IgG 6 months after infection in children who [...]

Published
2021
Full Text
View/download PDF

15. Respiratory Syncytial Virus and Influenza Infections in Children in Ulaanbaatar, Mongolia, 2015–2021.

Author

Do, Lien Anh Ha, Tsedenbal, Naranzul, Khishigmunkh, Chimidregzen, Tserendulam, Bazarkhuu, Altanbumba, Lkhagvadorj, Luvsantseren, Dashtseren, Ulziibayar, Munkhchuluun, Suuri, Bujinlkham, Narangerel, Dorj, Tsolmon, Bilegtsaikhan, Demberelsuren, Sodbayar, Pell, Casey L, Manna, Sam, Satzke, Catherine, Nguyen, Cattram, Mungun, Tuya, von Mollendorf, Claire, Badarch, Darmaa, and Mulholland, Kim

Subjects
*RESPIRATORY syncytial virus infections, *PNEUMOCOCCAL pneumonia, *RESPIRATORY infections, *INFLUENZA viruses, *INFLUENZA, *PNEUMOCOCCAL vaccines
Abstract

Background: Data available for RSV and influenza infections among children < 2 years in Mongolia are limited. We present data from four districts of Ulaanbaatar from April 2015 to June 2021. Methods: This study was nested in an enhanced surveillance project evaluating pneumococcal conjugate vaccine (PCV13) impact on the incidence of hospitalized lower respiratory tract infections (LRTIs). Our study was restricted to children aged < 2 years with arterial O2 saturation < 93% and children with radiological pneumonia. Nasopharyngeal (NP) swabs collected at admission were tested for RSV and influenza using qRT‐PCR. NP swabs of all patients with radiological pneumonia and of a subset of randomly selected NP swabs were tested for S. pneumoniae (S.p.) by qPCR and for serotypes by culture and DNA microarray. Results: Among 5705 patients, 2113 (37.0%) and 386 (6.8%) had RSV and influenza infections, respectively. Children aged 2–6 months had a higher percentage of very severe RSV infection compared to those older than 6 months (42.2% versus 31.4%, p‐value Fisher's exact = 0.001). S.p. carriage was detected in 1073/2281 (47.0%) patients. Among S.p. carriage cases, 363/1073 (33.8%) had S.p. and RSV codetection, and 82/1073 (7.6%) had S.p. and influenza codetection. S.p. codetection with RSV/influenza was not associated with more severe LRTIs, compared to only RSV/influenza cases. Conclusion: In Mongolia, RSV is an important pathogen causing more severe LRTI in children under 6 months of age. Codetection of RSV or influenza virus and S.p. was not associated with increased severity. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

17. Host Transcription Profile in Nasal Epithelium and Whole Blood of Hospitalized Children Under 2 Years of Age With Respiratory Syncytial Virus Infection

Author

Do, Lien Anh Ha, Pellet, Johann, van Doorn, H. Rogier, Tran, Anh Tuan, Nguyen, Bach Hue, Tran, Thi Thu Loan, Tran, Quynh Huong, Vo, Quoc Bao, Dac, Nguyen Anh Tran, Trinh, Hong Nhien, Nguyen, Thi Thanh Hai, Le Binh, Bao Tinh, Nguyen, Huu Mai Khanh, Nguyen, Minh Tien, Thai, Quang Tung, Vo, Thanh Vu, Ngo, Ngoc Quang Minh, Dang, Thi Kim Huyen, Cao, Ngoc Huong, Van Tran, Thu, Ho, Lu Viet, De Meulder, Bertrand, Auffray, Charles, Hofstra, Jorrit-Jan, Farrar, Jeremy, Bryant, Juliet E., de Jong, Menno, and Hibberd, Martin L.

Published
2018

19. Immune responses to SARS-CoV-2 in three children of parents with symptomatic COVID-19

Author

Tosif, Shidan, Neeland, Melanie R., Sutton, Philip, Licciardi, Paul V., Sarkar, Sohinee, Selva, Kevin J., Do, Lien Anh Ha, Donato, Celeste, Quan Toh, Zheng, Higgins, Rachel, Van de Sandt, Carolien, Lemke, Melissa M., Lee, Christina Y., Shoffner, Suzanne K., Flanagan, Katie L., Arnold, Kelly B., Mordant, Francesca L., Mulholland, Kim, Bines, Julie, Dohle, Kate, Pellicci, Daniel G., Curtis, Nigel, McNab, Sarah, Steer, Andrew, Saffery, Richard, Subbarao, Kanta, Chung, Amy W., Kedzierska, Katherine, Burgner, David P., and Crawford, Nigel W.

Published
2020
Full Text
View/download PDF

20. Impact and cost-effectiveness of strategies to prevent respiratory syncytial virus (RSV) disease in Vietnam: A modelling study.

Author

Do, Lien Anh Ha, Le, Nguyen Thanh Nhan, Mahmud, Sarwat, Mulholland, Kim, Pecenka, Clint, and Clark, Andrew

Subjects
*RESPIRATORY syncytial virus, *RESPIRATORY syncytial virus infections, *COST effectiveness, *MIDDLE-income countries, *MONOCLONAL antibodies, *PLANT protection
Abstract

New prevention strategies for respiratory syncytial virus (RSV) are emerging, but it is unclear if they will be cost-effective in low- and middle-income countries. We evaluated the potential impact and cost-effectiveness of two strategies to prevent RSV disease in young children in Vietnam. We used a static cohort model with a finely disaggregated age structure (weeks of age <5 years) to calculate the RSV disease burden in Vietnam, with and without a single dose of maternal vaccine (RSVpreF, Pfizer) or of monoclonal antibody (Nirsevimab, Sanofi, Astra Zeneca). Each strategy was compared to no pharmaceutical intervention, and to each other. We assumed both strategies would be administered year round over a ten-year period. The primary outcome measure was the cost per disability-adjusted life year (DALY) averted, from a societal perspective. We ran probabilistic and deterministic uncertainty analyses. With central input assumptions for RSVpreF vaccine ($25/dose, 69 % efficacy, 6 months protection) and Nirsevimab ($25/dose, 77 % efficacy, 5 months protection), both options had similar cost-effectiveness ($3442 versus $3367 per DALY averted) when compared separately to no pharmaceutical intervention. RSVpreF vaccine had a lower net cost than Nirsevimab (net discounted cost of $213 m versus $264 m) but prevented fewer RSV deaths (24 % versus 31 %). Our results were very sensitive to assumptions about the dose price, efficacy, and duration of protection. At $5/dose and a willingness-to-pay threshold of 0.5 times the national GDP per capita, both prevention strategies have the potential to be cost-effective. RSVpreF vaccine and Nirsevimab may be cost-effective in Vietnam if appropriately priced. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

22. Enterovirus D68 in Viet Nam (2009-2015) [version 2; referees: 3 approved]

Author

Nguyen Thi Han Ny, Nguyen To Anh, Vu Thi Ty Hang, Lam Anh Nguyet, Tran Tan Thanh, Do Quang Ha, Ngo Ngoc Quang Minh, Do Lien Anh Ha, Angela McBride, Ha Manh Tuan, Stephen Baker, Pham Thi Thanh Tam, Tran My Phuc, Dang Thao Huong, Tran Quoc Loi, Nguyen Tran Anh Vu, Nguyen Van Hung, Tran Thi Thuy Minh, Nguyen Van Xang, Nguyen Dong, Ho Dang Trung Nghia, Nguyen Van Vinh Chau, Guy Thwaites, H. Rogier van Doorn, Catherine Anscombe, Tan Le Van, and VIZIONS Consortium

Subjects
Viral Infections (without HIV), Virology, Medicine, Science
Abstract

Background: Since 1962, enterovirus D68 (EV-D68) has been implicated in multiple outbreaks and sporadic cases of respiratory infection worldwide, especially in the USA and Europe with an increasing frequency between 2010 and 2014. We describe the detection, associated clinical features and molecular characterization of EV-D68 in central and southern Viet Nam between 2009 and 2015. Methods: Enterovirus/rhinovirus PCR positive respiratory or CSF samples taken from children and adults with respiratory/central nervous system infections in Viet Nam were tested by an EV-D68 specific PCR. The included samples were derived from 3 different observational studies conducted at referral hospitals across central and southern Viet Nam 2009 2015. Whole-genome sequencing was carried out using a MiSeq based approach. Phylogenetic reconstruction and estimation of evolutionary rate and recombination were carried out in BEAST and Recombination Detection Program, respectively. Results: EV-D68 was detected in 21/625 (3.4%) enterovirus/rhinovirus PCR positive respiratory samples but in none of the 15 CSF. All the EV-D68 patients were young children (age range: 11.8 – 24.5 months) and had moderate respiratory infections. Phylogenetic analysis suggested that the Vietnamese sequences clustered with those from Asian countries, of which 9 fell in the B1 clade, and the remaining sequence was identified within the A2 clade. One intra sub-clade recombination event was detected, representing the second reported recombination within EV-D68. The evolutionary rate of EV-D68 was estimated to be 5.12E -3 substitutions/site/year. Phylogenetic analysis indicated that the virus was imported into Viet Nam in 2008. Conclusions: We have demonstrated for the first time EV-D68 has been circulating at low levels in Viet Nam since 2008, associated with moderate acute respiratory infection in children. EV-D68 in Viet Nam is most closely related to Asian viruses, and clusters separately from recent US and European viruses that were suggested to be associated with acute flaccid paralysis.

Published
2018
Full Text
View/download PDF

26. Enterovirus D68 in Viet Nam (2009-2015) [version 1; referees: 2 approved, 1 approved with reservations]

Author

Nguyen Thi Han Ny, Nguyen To Anh, Vu Thi Ty Hang, Lam Anh Nguyet, Tran Tan Thanh, Do Quang Ha, Ngo Ngoc Quang Minh, Do Lien Anh Ha, Angela McBride, Ha Manh Tuan, Stephen Baker, Pham Thi Thanh Tam, Tran My Phuc, Dang Thao Huong, Tran Quoc Loi, Nguyen Tran Anh Vu, Nguyen Van Hung, Tran Thi Thuy Minh, Nguyen Van Xang, Nguyen Dong, Ho Dang Trung Nghia, Nguyen Van Vinh Chau, Guy Thwaites, H. Rogier van Doorn, Catherine Anscombe, Tan Le Van, and VIZIONS Consortium

Subjects
Viral Infections (without HIV), Virology, Medicine, Science
Abstract

Background: Since 1962, enterovirus D68 (EV-D68) has been implicated in multiple outbreaks and sporadic cases of respiratory infection worldwide, but especially in the USA and Europe with an increasing frequency between 2010 and 2014. We describe the detection, associated clinical features and molecular characterization of EV-D68 in central and southern Viet Nam between 2009 and 2015. Methods: Enterovirus/rhinovirus PCR positive respiratory or CSF samples taken from children and adults with respiratory/central nervous system infections in Viet Nam were tested by an EV-D68 specific PCR. The included samples were derived from 3 different observational studies conducted at referral hospitals across central and southern Viet Nam between 2009 and 2015. Whole-genome sequencing was carried out using a MiSeq based approach. Phylogenetic reconstruction and estimation of evolutionary rate and recombination were carried out in BEAST and Recombination Detection Program, respectively. Results: EV-D68 was detected in 21/625 (3.4%) enterovirus/rhinovirus PCR positive respiratory samples but in none of the 15 CSF. All the EV-D68 patients were young children (age range: 11.8 – 24.5 months) and had moderate respiratory infections. Phylogenetic analysis suggested that the Vietnamese sequences clustered with those from Asian countries, of which 9 fell in the B1 clade, and the remaining sequence was identified within the A2 clade. One intra sub-clade recombination event was detected, representing the second reported recombination within EV-D68. The evolutionary rate of EV-D68 was estimated to be 5.12E-3 substitutions/site/year. Phylogenetic analysis indicated that the virus was imported into Viet Nam in 2008. Conclusions: We have demonstrated for the first time EV-D68 has been circulating at low levels in Viet Nam since 2008, associated with moderate acute respiratory infection in children. EV-D68 in Viet Nam is most closely related to Asian viruses, and clusters separately from recent US and European viruses that were suggested to be associated with acute flaccid paralysis.

Published
2017
Full Text
View/download PDF

29. Virology and immune dynamics reveal high household transmission of ancestral SARS‐CoV‐2 strain

Author

Tosif, Shidan, primary, Haycroft, Ebene R., additional, Sarkar, Sohinee, additional, Toh, Zheng Quan, additional, Do, Lien Anh Ha, additional, Donato, Celeste M., additional, Selva, Kevin J., additional, Hoq, Monsurul, additional, Overmars, Isabella, additional, Nguyen, Jill, additional, Lee, Lai‐Yang, additional, Clifford, Vanessa, additional, Daley, Andrew, additional, Mordant, Francesa L., additional, McVernon, Jodie, additional, Mulholland, Kim, additional, Marcato, Adrian J., additional, Smith, Miranda Z., additional, Curtis, Nigel, additional, McNab, Sarah, additional, Saffery, Richard, additional, Kedzierska, Katherine, additional, Subarrao, Kanta, additional, Burgner, David, additional, Steer, Andrew, additional, Bines, Julie E., additional, Sutton, Philip, additional, Licciardi, Paul V., additional, Chung, Amy W., additional, Neeland, Melanie R., additional, and Crawford, Nigel W., additional

Published
2022
Full Text
View/download PDF

30. Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in children younger than 5 years in 2019: a systematic analysis

Author

Li, You, primary, Wang, Xin, additional, Blau, Dianna M, additional, Caballero, Mauricio T, additional, Feikin, Daniel R, additional, Gill, Christopher J, additional, Madhi, Shabir A, additional, Omer, Saad B, additional, Simões, Eric A F, additional, Campbell, Harry, additional, Pariente, Ana Bermejo, additional, Bardach, Darmaa, additional, Bassat, Quique, additional, Casalegno, Jean-Sebastien, additional, Chakhunashvili, Giorgi, additional, Crawford, Nigel, additional, Danilenko, Daria, additional, Do, Lien Anh Ha, additional, Echavarria, Marcela, additional, Gentile, Angela, additional, Gordon, Aubree, additional, Heikkinen, Terho, additional, Huang, Q Sue, additional, Jullien, Sophie, additional, Krishnan, Anand, additional, Lopez, Eduardo Luis, additional, Markić, Joško, additional, Mira-Iglesias, Ainara, additional, Moore, Hannah C, additional, Moyes, Jocelyn, additional, Mwananyanda, Lawrence, additional, Nokes, D James, additional, Noordeen, Faseeha, additional, Obodai, Evangeline, additional, Palani, Nandhini, additional, Romero, Candice, additional, Salimi, Vahid, additional, Satav, Ashish, additional, Seo, Euri, additional, Shchomak, Zakhar, additional, Singleton, Rosalyn, additional, Stolyarov, Kirill, additional, Stoszek, Sonia K, additional, von Gottberg, Anne, additional, Wurzel, Danielle, additional, Yoshida, Lay-Myint, additional, Yung, Chee Fu, additional, Zar, Heather J, additional, Nair, Harish, additional, Abram, Michael, additional, Aerssens, Jeroen, additional, Alafaci, Annette, additional, Balmaseda, Angel, additional, Bandeira, Teresa, additional, Barr, Ian, additional, Batinović, Ena, additional, Beutels, Philippe, additional, Bhiman, Jinal, additional, Blyth, Christopher C, additional, Bont, Louis, additional, Bressler, Sara S, additional, Cohen, Cheryl, additional, Cohen, Rachel, additional, Costa, Anna-Maria, additional, Crow, Rowena, additional, Daley, Andrew, additional, Dang, Duc-Anh, additional, Demont, Clarisse, additional, Desnoyers, Christine, additional, Díez-Domingo, Javier, additional, Divarathna, Maduja, additional, du Plessis, Mignon, additional, Edgoose, Madeleine, additional, Ferolla, Fausto Martín, additional, Fischer, Thea K, additional, Gebremedhin, Amanuel, additional, Giaquinto, Carlo, additional, Gillet, Yves, additional, Hernandez, Roger, additional, Horvat, Come, additional, Javouhey, Etienne, additional, Karseladze, Irakli, additional, Kubale, John, additional, Kumar, Rakesh, additional, Lina, Bruno, additional, Lucion, Florencia, additional, MacGinty, Rae, additional, Martinon-Torres, Federico, additional, McMinn, Alissa, additional, Meijer, Adam, additional, Milić, Petra, additional, Morel, Adrian, additional, Mulholland, Kim, additional, Mungun, Tuya, additional, Murunga, Nickson, additional, Newbern, Claire, additional, Nicol, Mark P, additional, Odoom, John Kofi, additional, Openshaw, Peter, additional, Ploin, Dominique, additional, Polack, Fernando P, additional, Pollard, Andrew J, additional, Prasad, Namrata, additional, Puig-Barberà, Joan, additional, Reiche, Janine, additional, Reyes, Noelia, additional, Rizkalla, Bishoy, additional, Satao, Shilpa, additional, Shi, Ting, additional, Sistla, Sujatha, additional, Snape, Matthew, additional, Song, Yanran, additional, Soto, Giselle, additional, Tavakoli, Forough, additional, Toizumi, Michiko, additional, Tsedenbal, Naranzul, additional, van den Berge, Maarten, additional, Vernhes, Charlotte, additional, von Mollendorf, Claire, additional, Walaza, Sibongile, additional, and Walker, Gregory, additional

Published
2022
Full Text
View/download PDF

31. Comparison of Seroconversion in Children and Adults With Mild COVID-19

Author

Toh, Zheng Quan, primary, Anderson, Jeremy, additional, Mazarakis, Nadia, additional, Neeland, Melanie, additional, Higgins, Rachel A., additional, Rautenbacher, Karin, additional, Dohle, Kate, additional, Nguyen, Jill, additional, Overmars, Isabella, additional, Donato, Celeste, additional, Sarkar, Sohinee, additional, Clifford, Vanessa, additional, Daley, Andrew, additional, Nicholson, Suellen, additional, Mordant, Francesca L., additional, Subbarao, Kanta, additional, Burgner, David P., additional, Curtis, Nigel, additional, Bines, Julie E., additional, McNab, Sarah, additional, Steer, Andrew C., additional, Mulholland, Kim, additional, Tosif, Shidan, additional, Crawford, Nigel W., additional, Pellicci, Daniel G., additional, Do, Lien Anh Ha, additional, and Licciardi, Paul V., additional

Published
2022
Full Text
View/download PDF

33. Global, Regional, and National Disease Burden Estimates of Acute Lower Respiratory Infections Due to Respiratory Syncytial Virus in Young Children in 2019: A Systematic Analysis

Author

Li, You, primary, Wang, Xin, additional, Blau, Dianna M., additional, Caballero, Mauricio T., additional, Feikin, Daniel, additional, Gill, Christopher John, additional, Madhi, Shabir Ahmed, additional, Omer, Saad B., additional, Simões, Eric A.F., additional, Campbell, Harry, additional, Bermejo Pariente, Ana, additional, Bardach, Darmaa, additional, Bassat, Quique, additional, Casalegno, Jean-Sebastien, additional, Chakhunashvili, Giorgi, additional, Crawford, Nigel W., additional, Danilenko, Daria, additional, Do, Lien Anh Ha, additional, Echavarria, Marcela, additional, Gentile, Angela, additional, Gordon, Aubree, additional, Heikkinen, Terho, additional, Huang, Sue, additional, Jullien, Sophie, additional, Krishnan, Anand, additional, López, Eduardo Luis, additional, Markić, Joško, additional, Mira-Iglesias, Ainara, additional, Moore, Hannah C., additional, Moyes, Jocelyn, additional, Mwananyanda, Lawrence, additional, Nokes, D. James, additional, Noordeen, Faseeha, additional, Obodai, Evangeline, additional, Palani, Nandhini, additional, Romero, Candice, additional, Salimi, Vahid, additional, SATAV, ASHISH RAMBHAU, additional, Seo, Euri, additional, Shchomak, Zakhar, additional, Singleton, Rosalyn, additional, Stolyarov, Kirill, additional, Stoszek, Sonia K., additional, Von Gottberg, Ann, additional, Wurzel, Danielle, additional, Yoshida, Lay-Myint, additional, Yung, Chee Fu, additional, Zar, Heather, additional, Network Group, Respiratory Virus Global Epidemiolo, additional, Nair, Harish, additional, and Group, RESCEU Investigators, additional

Published
2022
Full Text
View/download PDF

35. Immune Profiling of Cord Blood From Preterm and Term Infants Reveals Distinct Differences in Pro-Inflammatory Responses

Author

Anderson, Jeremy, primary, Thang, Cao Minh, additional, Thanh, Le Quang, additional, Dai, Vo Thi Trang, additional, Phan, Van Thanh, additional, Nhu, Bui Thi Hong, additional, Trang, Do Ngoc Xuan, additional, Trinh, Phan Thi Phuong, additional, Nguyen, Thuong Vu, additional, Toan, Nguyen Trong, additional, Harpur, Christopher M., additional, Mulholland, Kim, additional, Pellicci, Daniel G., additional, Do, Lien Anh Ha, additional, and Licciardi, Paul V., additional

Published
2021
Full Text
View/download PDF

36. Global patterns in monthly activity of influenza virus, respiratory syncytial virus, parainfluenza virus, and metapneumovirus: a systematic analysis

Author

Li, You, Reeves, Rachel M., Wang, Xin, Bassat, Quique, Brooks, W. Abdullah, Cohen, Cheryl, Moore, David P., Nunes, Marta, Rath, Barbara, Campbell, Harry, Nair, Harish, Acacio, Sozinho, Alonso, Wladimir J., Antonio, Martin, Ayora Talavera, Guadalupe, Badarch, Darmaa, Baillie, Vicky L., Barrera-Badillo, Gisela, Bigogo, Godfrey, Broor, Shobha, Bruden, Dana, Buchy, Philippe, Byass, Peter, Chipeta, James, Clara, Wilfrido, Dang, Duc-Anh, de Freitas Lazaro Emediato, Carla Cecilia, de Jong, Menno, Diaz-Quinonez, Jose Alberto, Do, Lien Anh Ha, Fasce, Rodrigo A., Feng, Luzhao, Ferson, Mark J., Gentile, Angela, Gessner, Bradford D., Goswami, Doli, Goyet, Sophie, Grijalva, Carlos G., Halasa, Natasha, Hellferscee, Orienka, Hessong, Danielle, Homaira, Nusrat, Jara, Jorge, Kahn, Kathleen, Khuri-Bulos, Najwa, Kotloff, Karen L., Lanata, Claudio F., Lopez, Olga, Lopez Bolanos, Maria Renee, Lucero, Marilla G., Lucion, Florencia, Lupisan, Socorro P., Madhi, Shabir A., McCracken, John P., Mekgoe, Omphile, Moraleda, Cinta, Moyes, Jocelyn, Mulholland, Kim, Munywoki, Patrick K., Naby, Fathima, Thanh Hung Nguyen, Nicol, Mark P., Nokes, D. James, Noyola, Daniel E., Onozuka, Daisuke, Palani, Nandhini, Poovorawan, Yong, Rahman, Mustafizur, Ramaekers, Kaat, Romero, Candice, Schlaudecker, Elizabeth P., Schweiger, Brunhilde, Seidenberg, Phil, Simoes, Eric A. F., Singleton, Rosalyn, Sistla, Sujatha, Sturm-Ramirez, Katharine, Suntronwong, Nungruthai, Sutanto, Agustinus, Tapia, Milagritos D., Thamthitiwat, Somsak, Thongpan, Ilada, Tillekeratne, Gayani, Tinoco, Yeny O., Treurnicht, Florette K., Turner, Claudia, Turner, Paul, van Doorn, Rogier, Van Ranst, Marc, Visseaux, Benoit, Waicharoen, Sunthareeya, Wang, Jianwei, Yoshida, Lay-Myint, Zar, Heather J., Shi, Ting, Zhang, Shanshan, Openshaw, Peter, Wedzicha, Jadwicha, Falsey, Ann, Miller, Mark, Beutels, Philippe, Bont, Louis, Pollard, Andrew, Molero, Eva, Martinon-Torres, Federico, Heikkinen, Terho, Meijer, Adam, Fischer, Thea Kolsen, van den Berge, Maarten, Giaquinto, Carlo, Mikolajczyk, Rafael, Hackett, Judy, Dillon, Laura, Tafesse, Eskinder, Cai, Bing, Knirsch, Charles, Lopez, Antonio Gonzalez, Dieussaert, Ilse, Dermateau, Nadia, Leach, Amanda, Stoszek, Sonia K., Gallichan, Scott, Kieffer, Alexia, Demont, Clarisse, Denouel, Angeline, Cheret, Arnaud, Gavart, Sandra, Aerssens, Jeroen, Wyffels, Veronique, Cleenewerck, Matthias, Fuentes, Robert, Rosen, Brian, RSV Global Epidemiology Network, RESCEU Investigators, Groningen Research Institute for Asthma and COPD (GRIAC), Ramaekers, Kaat, Van Ranst, Marc, RSV Global Epidemiology Network and RESCEU investigators, VU University medical center, APH - Global Health, Graduate School, Medical Microbiology and Infection Prevention, and AII - Infectious diseases

Subjects
Male, Respiratory diseases, Epidemiology, viruses, RESCEU investigators, EPIDEMICS, 030231 tropical medicine, Respiratory Syncytial Virus Infections, Global Health, Virus, Malalties de l'aparell respiratori, 03 medical and health sciences, 0302 clinical medicine, stomatognathic system, Human metapneumovirus, Parainfluenza virus, Influenza, Human, DRIVERS, Humans, RSV Global Epidemiology Network, Metapneumovirus, 030212 general & internal medicine, Respiratory system, Epidemiologia, Paramyxoviridae Infections, biology, lcsh:Public aspects of medicine, virus diseases, lcsh:RA1-1270, Public Health, Global Health, Social Medicine and Epidemiology, General Medicine, respiratory system, biology.organism_classification, Virology, respiratory tract diseases, 3. Good health, SEASONALITY, Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi, Influenza A virus, INFECTIONS, Respiratory Syncytial Virus, Human, Respiratory virus, Female, Human medicine, RC
Abstract

BACKGROUND: Influenza virus, respiratory syncytial virus, parainfluenza virus, and metapneumovirus are the most common viruses associated with acute lower respiratory infections in young children (

Published
2019
Full Text
View/download PDF

37. Characterization of hospital and community-acquired respiratory syncytial virus in children with severe lower respiratory tract infections in Ho Chi Minh City, Vietnam, 2010

Author

Tuan, Tran Anh, Thanh, Tran Tan, Hai, Nguyen thi Thanh, Tinh, Le Binh Bao, Kim, Le thi Ngoc, Do, Lien Anh Ha, BʼKrong, Nguyen thi Thuy Chinh, Tham, Nguyen thi, Hang, Vu thi Ty, Merson, Laura, Farrar, Jeremy, Thuong, Tang Chi, de Jong, Menno D., Schultsz, Constance, and van Doorn, Rogier H

Published
2015
Full Text
View/download PDF

38. Reduced seroconversion in children compared to adults with mild COVID-19

Author

Toh, Zheng Quan, primary, Anderson, Jeremy, additional, Mazarakis, Nadia, additional, Neeland, Melanie, additional, Higgins, Rachel A, additional, Rautenbacher, Karin, additional, Dohle, Kate, additional, Nguyen, Jill, additional, Overmars, Isabelle, additional, Donato, Celeste, additional, Sarkar, Sohinee, additional, Clifford, Vanessa, additional, Daley, Andrew, additional, Nicholson, Suellen, additional, Mordant, Francesca L, additional, Subbarao, Kanta, additional, Burgner, David, additional, Curtis, Nigel, additional, Bines, Julie E, additional, McNab, Sarah, additional, Steer, Andrew C, additional, Mulholland, Kim, additional, Tosif, Shidan, additional, Crawford, Nigel W, additional, Pellicci, Daniel G, additional, Do, Lien Anh Ha, additional, and Licciardi, Paul, additional

Published
2021
Full Text
View/download PDF

39. Children and Adults in a Household Cohort Study Have Robust Longitudinal Immune Responses Following SARS-CoV-2 Infection or Exposure

Author

Neeland, Melanie R., primary, Bannister, Samantha, additional, Clifford, Vanessa, additional, Nguyen, Jill, additional, Dohle, Kate, additional, Overmars, Isabella, additional, Toh, Zheng Quan, additional, Anderson, Jeremy, additional, Donato, Celeste M., additional, Sarkar, Sohinee, additional, Do, Lien Anh Ha, additional, McCafferty, Conor, additional, Licciardi, Paul V., additional, Ignjatovic, Vera, additional, Monagle, Paul, additional, Bines, Julie E., additional, Mulholland, Kim, additional, Curtis, Nigel, additional, McNab, Sarah, additional, Steer, Andrew C., additional, Burgner, David P., additional, Saffery, Richard, additional, Tosif, Shidan, additional, and Crawford, Nigel W., additional

Published
2021
Full Text
View/download PDF

40. Factors associated with severe respiratory syncytial virus disease in hospitalised children: a retrospective analysis

Author

Anderson, Jeremy, primary, Oeum, Michelle, additional, Verkolf, Eva, additional, Licciardi, Paul V, additional, Mulholland, Kim, additional, Nguyen, Cattram, additional, Chow, Kim, additional, Waller, Gregory, additional, Costa, Anna-Maria, additional, Daley, Andrew, additional, Crawford, Nigel W, additional, Babl, Franz E, additional, Duke, Trevor, additional, Do, Lien Anh Ha, additional, and Wurzel, Danielle, additional

Published
2021
Full Text
View/download PDF

41. Immune Responses in an Infant with Congenital Heart Disease and Severe COVID-19&nbsp;

Author

Licciardi, Paul, primary, Wurzel, Danielle, additional, Neeland, Melanie, additional, Anderson, Jeremy, additional, Abo, Yara-Natalie, additional, Do, Lien Anh Ha, additional, Donato, Celeste, additional, Bines, Julie, additional, Toh, Zheng Quan, additional, Higgins, Rachel, additional, Jalali, Sedi, additional, Cole, Theresa, additional, Subbarao, Kanta, additional, McMinn, Alissa, additional, Dohle, Kate, additional, Haeusler, Gabrielle, additional, McNab, Sarah, additional, Alafaci, Annette, additional, Overmars, Isabella, additional, Clifford, Vanessa, additional, Lee, Lai-Yang, additional, Daly, Andrew, additional, Buttery, Jim, additional, Bryant, Penelope, additional, Burgner, David, additional, Steer, Andrew, additional, Tosif, Shidan, additional, Konstantinov, Igor, additional, Duke, Trevor, additional, Pellicci, Dan, additional, and Crawford, Nigel, additional

Published
2021
Full Text
View/download PDF

45. use of dried blood spots for the serological evaluation of SARS-CoV-2 antibodies.

Author

Toh, Zheng Quan, Higgins, Rachel A, Anderson, Jeremy, Mazarakis, Nadia, Do, Lien Anh Ha, Rautenbacher, Karin, Ramos, Pedro, Dohle, Kate, Tosif, Shidan, Crawford, Nigel, Mulholland, Kim, and Licciardi, Paul V

Subjects
SARS-CoV-2, IMMUNOGLOBULINS, SEROLOGY, BLOOD collection, COMPARATIVE studies, ENZYME-linked immunosorbent assay, VIRAL antibodies, POLYMERASE chain reaction, LONGITUDINAL method
Abstract

Background To determine if dried blood spot specimens (DBS) can reliably detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies, we compared the SARS-CoV-2 IgG antibody response in paired serum and eluates from DBS specimens. Methods A total of 95 paired DBS and serum samples were collected from 74 participants (aged 1–63 years) as part of a household cohort study in Melbourne, Australia. SARS-CoV-2 IgG antibodies specific for the receptor-binding domain (RBD) and S1 proteins between serum and eluates from DBS specimens were compared using an FDA-approved ELISA method. Results Among the 74 participants, 42% (31/74) were children and the rest were adults. A total of 16 children and 13 adults were SARS-CoV-2 positive by polymerase chain reaction. The IgG seropositivity rate was similar between serum and DBS specimens (18.9% (18/95) versus 16.8% (16/95)), respectively. Similar RBD and S1-specific IgG levels were detected between serum and DBS specimens. Serum IgG levels strongly correlated with DBS IgG levels (r = 0.99, P  < 0.0001) for both SARS-CoV-2 proteins. Furthermore, antibodies remained stable in DBS specimens for >3 months. Conclusions DBS specimens can be reliably used as an alternative to serum samples for SARS-CoV-2 antibody measurement. The use of DBS specimens would facilitate serosurveillance efforts particularly in hard-to-reach populations and inform public health responses including COVID-19 vaccination strategies. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

48. Pulmonary Deposition of Radionucleotide-Labeled Palivizumab: Proof-of-Concept Study

Author

Rajapaksa, Anushi E., primary, Do, Lien Anh Ha, additional, Suryawijaya Ong, Darren, additional, Sourial, Magdy, additional, Veysey, Duncan, additional, Beare, Richard, additional, Hughes, William, additional, Yang, William, additional, Bischof, Robert J., additional, McDonnell, Amarin, additional, Eu, Peter, additional, Yeo, Leslie Y., additional, Licciardi, Paul V., additional, and Mulholland, Edward K., additional

Published
2020
Full Text
View/download PDF

49. Immune responses to SARS-CoV-2 in children of parents with symptomatic COVID-19

Author

Tosif, Shidan, primary, Neeland, Melanie, additional, Sutton, Philip, additional, Licciardi, Paul, additional, Sarkar, Sohinee, additional, Selva, Kevin, additional, Do, Lien Anh Ha, additional, Donato, Celeste, additional, Toh, Zheng Quan, additional, Higgins, Rachel, additional, de Sandt, Carolien van, additional, Lemke, Melissa, additional, Lee, Christina, additional, Shoffner, Suzanne, additional, Flanagan, Katie, additional, Arnold, Kelly, additional, Mordant, Francesca, additional, Mulholland, Kim, additional, Bines, Julie, additional, Dohle, Kate, additional, Pellicci, Dan, additional, Curtis, Nigel, additional, McNab, Sarah, additional, Steer, Andrew, additional, Saffery, Richard, additional, Subbarao, Kanta, additional, Chung, Amy, additional, Kedzierska, Katherine, additional, Burgner, David, additional, and Crawford, Nigel, additional

Published
2020
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results