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Con el lanzamiento del protocolo MIDI, se han desarrollado nuevos recursos y posibilidades para la interpretación, composición y edición musical. Debido a la creciente expansión de las capacidades de almacenamiento y procesamiento de los ordenadores, también ha sido posible aumentar la calidad y la especificidad de las bibliotecas de muestras. En tal escenario, esta investigación de métodos mixtos tiene como objetivo principal investigar las actuaciones de los bateristas centrándose en desarrollar vías para incorporar sus características en la secuenciación MIDI. Derivado de ello, se establecieron cuatro objetivos específicos: 1) presentar los elementos básicos del muestreo y protocolo MIDI; 2) secuenciar las actuaciones de los bateristas; 3) aplicar cuestionarios de evaluación de la calidad de los audios generados en secuencia; 4) presentar el análisis de los resultados. Los resultados de la investigación demuestran que algunas características, como la variación del timbre y la dinámica, son determinantes para la aceptación de la secuencia por parte de la audiencia

In recent years, the rural agricultural economy in Vietnam has experienced outstanding shifting progress. The paper focuses on analyzing and evaluating an overview of the agricultural economy in Vietnam in the context of global climate change and global integration during industry 4.0. The results show that many advanced and modern models of association and cooperation which are effective in agriculture and rural areas have been applied to increase production efficiency. Science and technology applied to agriculture will increase the value of the agricultural sector in Vietnam. The innovations and prosperity of agricultural infrastructure combined with the implementation of the national scheme on restructuring agricultural sectors oriented to added value increase and sustainabe development will lead to a sustainable and climate adapted agriculture.

In the last two decades more and more studies have emphasized the central role of teachers' social and emotional competence in their teaching performance. In spite of this, there are not enough programs focused on developing teachers' social and emotional competence that are integrated into teacher education. This is particularly true in Vietnam where the concepts of social and emotional competence (SEC) and social and emotional learning (SEL) are rather new. In the study, we present four main emerging impact aspects of teachers' SEC including teachers' well-being and career motivation, teacher-student relationship, classroom management, and the effectiveness of SEL implementation. The article gives some recommendations for teacher education regarding SEC issue in Vietnam as well. These recommendations would contribute to develop a new approach of teacher education to meet the country's new general education curriculum enacted in 2020.

The MT-ATP8 gene encodes for A6L protein subunit belonging to the proton channel of the ATP synthase. MT-ATP8 gene’s mutations can affect the structure and function of the ATP synthase, which may cause diseases. In this study, alterations of MT-ATP8 gene were investigated in tumor tissues of patients with breast cancer and control blood samples using PCR combined with direct sequencing and PCR-RFLP methods, data were analyzed using bioinformatics tools and statistical methods. Sequencing results revealed 5 variants of MT-ATP8 gene on 35 breast tumor tissues and 26 blood samples of controls, of which two mutations C8414T and C8417T altered the amino acid sequence of the resulting protein. The C8417T was further screened by PCR-RFLP and was found in 0,98% (1/102) of breast tumor samples. This change lead to substitution of lecine to phenylalanine (L18F) in a highly conserved position of A6L and was predicted as probably damaging to the structure and function of the protein. Additionally, a 9 bp deletion was also observed in a non-coding region of mtDNA in 26,5% (27/102) of breast cancer patients and 27% (7/26) of controls. Thus, these results showed that C8417T variant in the conserved position of MT-ATP8 gene was rare and first identified in a group of breast cancer patients in Vietnam. 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The MT-ATP6 gene encodes for a protein subunit which is central to the proton channel of the ATP synthase. Mutations of MT-ATP6 gene can affect the ATP synthesis and may play an important role in the process of tumorigenesis. The purpose of this study was to identify potential changes of MT-ATP6 gene in pair of tumor and adjacent tissues of 102 patients with breast cancer and in blood samples of 65 controls by using direct DNA sequencing and PCR-RFLP method. Then, statistical analysis was used to analyze the association between some typical changes and pathological features of breast cancer. As a result, 20 changes in the MT-ATP6 gene in 35 examined breast cancer tissues and 13 changes in 26 blood control samples were reported, of which 12 alterations altered the amino acid and a variant, 9183insC, had not been described in the literature so far. Most of the variants had low frequencies from 2.86% to 5.71%. Two variants, G9053A and G8584A, which changed the amino acid sequence and had high frequency, were screened in all samples. Our results indicated that the frequencies of G9053A and G8584A were 21,6% (22/102 cases) and 24,5% (25/102 cases) respectively in tissues of breast cancer patients and 18,5% (12/65 cases) in normal blood controls. However, there was no statistically significant difference in G9053A and G8485A rates between breast cancer patients and controls as well as between mtDNA alterations and the pathological features of breast cancer such as age, size of tumors, number of lymph nodes, size of lymph nodes, T stage, N stage, tumor differentiation and stages of disease. This study showed that the variations of MT-ATP6 gene differed from patient groups. In Vietnamese patients with breast cancer, the rates of G9053A and G8485A were relatively high but these changes were not statistically related to breast cancer.