1. The importance of the enzyme Gamma-glutamyltransferase in the pathogenic cluster in type2 diabetic patient
- Author
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Virgolici Bogdana, Dobre Maria Zinaida, Lixandru Daniela, Petcu Laura, Picu Ariana, Ionescu-Târgovişte Constantin, Greabu Maria, and Bacanu Elena Violeta
- Subjects
alanine aminotransferase ,chemoattractant protein 1 ,monocyte ,gamma glutamyl transpeptidase ,insulin resistance ,intercellular adhesion molecule-1 ,oxidative stress ,tumor necrosis factor-α ,type 2 diabetes mellitus ,Internal medicine ,RC31-1245 - Abstract
Introduction. Gamma-glutamyltransferase (GGT) is a liver enzyme involved in inflammation and oxidative stress. It is already known that MCP-1 (Monocyte Chemoattractant Protein-1) and TNF-α (tumour necrosis factor) as inflammatory markers, ICAM-1 (Intercellular Adhesion Molecule-1) as an endothelial dysfunctional marker, and glutathione, as an antioxidant, have abnormal levels in type 2 diabetic patients. The aim of this study was to evaluate the specific biological picture of type 2 diabetic patients that also associate higher GGT activity.
- Published
- 2024
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