214 results on '"Dole, William P."'
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2. Angiotensin receptor-neprilysin inhibition with LCZ696: a novel approach for the treatment of heart failure
3. Novel P2Y 12 adenosine diphosphate receptor antagonists for inhibition of platelet aggregation (II): Pharmacodynamic and pharmacokinetic characterization
4. Pharmacokinetics, Safety and Tolerability of Single and Multiple Oral Doses of Aliskiren in Healthy Chinese Subjects: A Randomized, Single-Blind, Parallel-Group, Placebo-Controlled Study
5. Clinical Pharmacokinetics and Pharmacodynamics of Aliskiren
6. Pharmacokinetics of the oral direct renin inhibitor aliskiren in combination with digoxin, atorvastatin, and ketoconazole in healthy subjects: the role of P-glycoprotein in the disposition of aliskiren
7. Effects of Aliskiren, a Direct Renin Inhibitor, on Cardiac Repolarization and Conduction in Healthy Subjects
8. Vildagliptin, a Novel Dipeptidyl Peptidase IV Inhibitor, Has No Pharmacokinetic Interactions With the Antihypertensive Agents Amlodipine, Valsartan, and Ramipril in Healthy Subjects
9. Pharmacokinetics of the Oral Direct Renin Inhibitor Aliskiren Alone and in Combination with Irbesartan in Renal Impairment
10. Dose proportionality and the effect of food on vildagliptin, a novel dipeptidyl peptidase IV inhibitor, in healthy volunteers
11. Evaluation of pharmacokinetic interactions between vildagliptin and digoxin in healthy volunteers
12. Effect of clopidogrel on the steady-state pharmacokinetics of fluvastatin
13. Pharmacokinetics, safety, and tolerability of the novel oral direct renin inhibitor aliskiren in elderly healthy subjects
14. Pharmacokinetics, safety, and tolerability of the oral renin inhibitor aliskiren in patients with hepatic impairment
15. Hypertension in mice lacking the proatrial natriuretic peptide convertase corin
16. Standardization of outcome measures in clinical trials of pharmacological treatment for abdominal aortic aneurysm
17. Pharmacokinetics and Pharmacodynamics of Aliskiren/Hydrochlorothiazide Single-Pill Combination Tablets and Free Combination of Aliskiren and Hydrochlorothiazide
18. Influence of Body Weight and Gender on the Pharmacokinetics, Pharmacodynamics, and Antihypertensive Efficacy of Aliskiren
19. Hormonal and metabolic effects of morning or evening dosing of the dipeptidyl peptidase IV inhibitor vildagliptin in patients with type 2 diabetes
20. Pharmacokinetics and Pharmacodynamics of LCZ696, a Novel Dual-Acting Angiotensin Receptor-Neprilysin Inhibitor (ARNi)
21. Pharmacokinetics and Pharmacodynamics of Vildagliptin in Healthy Chinese Volunteers
22. Characterization of a small molecule PAI-1 inhibitor, ZK4044
23. Pharmacokinetic Interaction of the Direct Renin Inhibitor Aliskiren with Furosemide and Extended-Release Isosorbide-5-Mononitrate in Healthy Subjects
24. The effect of age, gender, and body mass index on the pharmacokinetics and pharmacodynamics of vildagliptin in healthy volunteers
25. The Influence of Hepatic Impairment on the Pharmacokinetics of Vildagliptin: 2024-PO
26. Inhibition of Rho-kinase by fasudil attenuated angiotensin II-induced cardiac hypertrophy in apolipoprotein E deficient mice
27. Coupling of a New, Active Morphine Derivative to Sepharose for Affinity Chromatography
28. Failure of vasodilator infusion to alter pulmonary diffusing capacity in systemic sclerosis
29. Pharmacokinetics and pharmacodynamics of vildagliptin in healthy Chinese volunteers
30. Systemic and tissue-specific effects of aliskiren on the RAAS and carbohydrate/lipid metabolism in obese patients with hypertension
31. Elucidation of the Role of Lectin-Like oxLDL Receptor-1 in the Metabolic Responses of Macrophages to Human oxLDL
32. Aldosterone synthase inhibition: cardiorenal protection in animal disease models and translation of hormonal effects to human subjects
33. Application of multianalyte microphysiometry to characterize macrophage metabolic responses to oxidized LDL and effects of an apoA-1 mimetic
34. Atrial natriuretic peptide regulates lipid mobilization and oxygen consumption in human adipocytes by activating AMPK
35. Total Cerebral Ischemia: Application of a New Model System To Studies of Cerebral Microcirculation
36. Total Cerebral Ischemia: A New Model System for the Study of Post-Cardiac Arrest Brain Damage
37. HORMONAL AND ELECTROLYTE RESPONSES TO THE ALDOSTERONE SYNTHASE INHIBITOR LCI699 IN SODIUM DEPLETED HEALTHY SUBJECTS
38. Study of the pharmacokinetic interaction of vildagliptin and metformin in patients with type 2 diabetes
39. A study of the pharmacokinetic interactions of the direct renin inhibitor aliskiren with metformin, pioglitazone and fenofibrate in healthy subjects
40. Renal and Hormonal Responses to Direct Renin Inhibition With Aliskiren in Healthy Humans
41. Measurement of bioactive renin concentration and renin activity in the presence of exogenous renin substrate: effect of the oral direct renin inhibitor aliskiren
42. A study of the pharmacokinetic interactions of the direct renin inhibitor aliskiren with allopurinol, celecoxib and cimetidine in healthy subjects
43. Novel P2Y12 adenosine diphosphate receptor antagonists for inhibition of platelet aggregation (II): Pharmacodynamic and pharmacokinetic characterization
44. Thiophene-Anthranilamides as Highly Potent and Orally Available Factor Xa Inhibitors
45. Effect of the novel oral dipeptidyl peptidase IV inhibitor vildagliptin on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects
46. Pharmacokinetics of the Oral Direct??Renin Inhibitor Aliskiren Alone and??in Combination with Irbesartan in??Renal Impairment
47. Fasudil, a Rho-Kinase Inhibitor, Attenuates Angiotensin II–Induced Abdominal Aortic Aneurysm in Apolipoprotein E–Deficient Mice by Inhibiting Apoptosis and Proteolysis
48. Inhibition of Rho-Kinase by Hydroxyfasudil Prevents Vasopressin-Induced Myocardial Ischemia in Donryu Rats by Attenuating Coronary Vasoconstriction
49. Urokinase plasminogen activator receptor promotes macrophage infiltration into the vascular wall of ApoE deficient mice
50. Urokinase-Type Plasminogen Activator Plays a Critical Role in Angiotensin II–Induced Abdominal Aortic Aneurysm
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