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Background: Stereoelectroencephalography (SEEG), as a minimally invasive method that can stably collect intracranial electroencephalographic information over long periods, has increasingly been applied in the diagnosis and treatment of intractable epilepsy in recent years. Over the past 20 years, with the advancement of materials science and computer science, the application scenarios of SEEG have greatly expanded. Bibliometrics, as a method of scientifically analyzing published literature, can summarize the evolutionary process in the SEEG field and offer insights into its future development prospects. Methods: This article selected all the literature records retrieved on November 4, 2024, from the Web of Science Core Collection (WoSCC). The search terms were as follows: "Stereo-electroencephalography" or "Stereo electroencephalography" or "Stereo-EEG" or "Stereo EEG" or "SEEG." The document types included were research articles and reviews. For analysis, VOSviewer, CiteSpace, and the R package "bibliometrix" were employed to analyze various aspects of the SEEG field, including authors, institutions, countries and regions, and research hotspots. Results: We reviewed a total of 1,383 non-duplicate literature records from 2002 to 2023, including 1,241 research articles, 116 review articles and 26 letters. Observing the annual publication trends, there has been an overall increase since 2002. The most influential journal in this field is Epilepsia. Other journals with considerable impact include Clinical Neurophysiology , Epileptic Disorders , Epilepsy Research , NeuroImage , and Epilepsy & Behavior. The top 5 most influential scholars are Bartolomei F, Tassi L, Nobili L, Russo GL, and Mc Gonigal A. As for the analysis of countries and regions, France occupies a leading position in this field with its early start, while China and the United States have also emerged as focal points since 2020. Research on SEEG has expanded beyond its initial use for localizing epileptic foci and thermo-coagulation treatments and have been employed as a medium to facilitate real-time prediction of epileptic seizures and enabling the exploration of brain network connectivity. Conclusion: As a minimally invasive tool for collecting intracranial electroencephalographic signals, SEEG continues to offer vast potential for development and application. Advances in electrode materials and robotic-assisted stereotactic techniques, have enabled SEEG to simultaneously sample multiple brain regions, acquire electrical signals from deep brain structures. These advantages significantly enhance the precision of epileptic focus localization in diagnosis and treatment, addressing the limitations of subdural electrodes. Through bibliometric analysis, this paper traces the developmental trajectory of SEEG and identifying key technological milestones, thereby providing a reference for scholarly research directions. [ABSTRACT FROM AUTHOR]

Objective: This study evaluated the therapeutic effects of open and minimally invasive surgeries in patients with drug-resistant epilepsy., Methods: This study systematically searched electronic databases, including PubMed, Web of Science, Embase, and the Cochrane Library, for randomized controlled trials, subsequent open-label expansion studies, prospective studies and retrospective studies on surgical procedures for patients with drug-resistant epilepsy. The main outcome was seizure-free status. A one-arm meta-analysis integrating data from all studies was performed to evaluate the treatment outcomes at multiple time points., Results: A total of 62 studies were included, representing 5958 individuals who received five treatment regimens. The analysis results indicate that anterior temporal lobectomy (ATL) and selective amygdalohippocampectomy is still the best choice for treating drug-resistant mesial temporal lobe epilepsy in adult epilepsy patients. During the overall follow-up period, the seizure free rates for ATL, selective amygdalohippocampectomy, laser interstitial thermal therapy, radiofrequency thermocoagulation, and gamma knife surgery were 62%, 70%, 58%, 47%, and 57%, respectively., Conclusions: Among the five surgical methods included in this study, ATL and selective amygdala hippocampal resection seem to have more advantages in postoperative epilepsy control compared to laser interstitial hyperthermia, radiofrequency thermocoagulation, and gamma knife surgery. Each surgical treatment method has its unique focus, and when choosing a specific method, it is necessary to consider the patient's specific situation, the type and location of epileptic seizures, and possible side effects. Treating physician will develop personalized treatment plans based on these factors to maximize treatment effectiveness and reduce risks., (Copyright © 2025 The Author(s). Published by Elsevier Inc. All rights reserved.)