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ObjectiveTo assess the specificity of P50 auditory-evoked potential in schizophrenic patients with violent and aggressive behaviors， so as to provide objective biological markers for predicting violent behaviors of schizophrenic patients.MethodsA total of135 schizophrenic patients who met the diagnostic criteria of the International Classification of Diseases， tenth edition （ICD-10） were divided into aggressive group （n=70） and non-aggressive group （n=65） according to the assessment results of the Modified Overt Aggression Scale （MOAS）， meantime， another 60 healthy individuals matched for age and gender were set as healthy group. Then the P50 auditory-evoked potentials of all selected individuals were measured using EP/EMG system （MEB-9200， Nihon Kohden， Japan）.ResultsAmp S2 of the aggressive group was significantly higher than those of the non-aggressive group and healthy control group， with statistical differences ［（9.86±6.04）μV vs. （7.06±3.88）μV， P=0.004； （9.86±6.04）μV vs. （7.82±3.87）μV， P=0.031］. The proportion of S2/S1 ratio ≥0.5 was 72.88%， 43.86% and 30.00% in aggressive group， non-aggressive group and healthy group， which was the highest in aggressive group， with statistical differences （P

This paper reported a case of psychosomatic medicine-based comprehensive treatment for a patient with gynecological malignant tumor suffering severe left hip pain after surgery and radiotherapy， with the aim of demonstrating the pathophysiological classification of pain arising from pathological damage， and providing references for the clinical study and practice of the psychosomatic multi-dimensional treatment mode for clinical "organic pain". This case suggested that the onset of pain， even in the presence of pathological damage， also involved a combination of pathological damage， somatic manifestations of anxiety and individual cognitive biases.

Background: The contribution of specific childhood trauma subtypes to suicidal thoughts and the associated mechanisms remains unclear, particularly in psychiatric patients. Methods: Face‐to‐face interviews were conducted with 449 psychiatric patients aged 18–73. Childhood trauma, self‐esteem, nonsuicidal self‐injury (NSSI), and suicidality were assessed retrospectively. Regression and moderated mediation model were employed to examine these relationships. Results: Emotional and sexual abuse were independently associated with suicidality. Female patients reported higher levels of emotional and sexual abuse, lower self‐esteem, and a heightened risk of suicide. Self‐esteem moderated the links between childhood trauma and NSSI, as well as between NSSI and suicidality. NSSI served as a mediator between childhood trauma and suicidality. Conclusions: Suicide prevention in mentally ill patients should involve targeted programs addressing specific childhood trauma. Additionally, psychological interventions to enhance self‐esteem and assist individuals engaging in NSSI behavior are crucial. [ABSTRACT FROM AUTHOR]

Objective: This study was undertaken to characterize somatic symptoms and related disorders (SSD) in epilepsy. Methods: Adults with epilepsy under active follow‐up at a tertiary epilepsy center were consecutively enrolled. The diagnosis of SSD was performed by an experienced psychologist based on the structured clinical interview for Statistical Manual of Mental Disorders, 5th edition. Detailed social/demographic data, epilepsy features, psychiatric features, life quality, disability, and economic burden were collected and compared between people with SSD and those without. Bodily distress syndrome checklist, Somatic Symptom Disorder–B Criteria Scale, Patient Health Questionnaire‐9, and Generalized Anxiety Disorder seven‐item scale (GAD‐7) were used to evaluate SSD individuals' somatic symptoms, symptom‐related psychological distress, and depressive and anxious symptoms. Quality of life and disability were assessed by Quality of Life in Epilepsy Inventory 31 (QOLIE‐31) and World Health Organization Disability Assessment Schedule V.2.0 (WHO DAS 2.0). A risk prediction nomogram was generated using least absolute shrinkage and selection operator (LASSO) analysis and validated. Results: One hundred fifty of 631 participants (24%) were diagnosed with SSD. In people with SSD, the top three most common somatic symptoms were memory impairment, headache, and dizziness (85%, 80%, and 78%, respectively), and multiple systems were involved in most (82%) people with SSD. Compared with people without SSD, those with SSD had lower QOLIE‐31 total scores, and higher WHO DAS 2.0 scores and disease economic burdens. LASSO analysis suggested that a history of severe traumatic brain injury, hippocampal sclerosis, low seizure worry and medication effects scores on QOLIE‐31, multiple systems affected by somatic symptoms, and a high GAD‐7 score were risk factors of SSD. The nomogram was validated for good accuracy in the training and testing cohorts. Significance: SSD are likely to be a common comorbidity in epilepsy and harm epilepsy prognosis. Our risk prediction nomogram was successfully developed but needs further validation in larger cohorts. [ABSTRACT FROM AUTHOR]