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2. High Efficiency Positron Accumulation for High-Precision Measurements

Author

Hoogerheide, S. Fogwell, Dorr, J. C., Novitski, E., and Gabrielse, G.

Subjects
Physics - Instrumentation and Detectors, Physics - Atomic Physics
Abstract

Positrons are accumulated within a Penning trap designed to make more precise measurements of the positron and electron magnetic moments. The retractable radioactive source used is weak enough to require no license for handling radioactive material and the radiation dosage one meter from the source gives an exposure several times smaller than the average radiation dose on the earth's surface. The 100 mK trap is mechanically aligned with the 4.2 K superconducting solenoid that produces a 6 tesla magnetic trapping field with a direct mechanical coupling., Comment: 7 pages, 9 figures

Published
2014
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4. Precise Matter and Antimatter Tests of the Standard Model with

Author

Gabrielse, G., Hoogerheide, S. Fogwell, Dorr, J., Novitski, E., Fujimori, Atsushi, Series editor, Kühn, Johann H., Series editor, Müller, Thomas, Series editor, Steiner, Frank, Series editor, Stwalley, William C., Series editor, Trümper, Joachim E, Series editor, Wölfle, Peter, Series editor, Woggon, Ulrike, Series editor, Quint, Wolfgang, editor, and Vogel, Manuel, editor

Published
2014
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7. Prevention in neurology

Author

Ceballos-Baumann, A. O., Wagner, A., Rühl, H., Mielke, U., Zett, H.-J., Schimrigk, K., Hummel, Manfred Max, Huffmann, Gert, Kornhuber, A. W., Becker, M., Lang, W., Lang, M., Uhl, F., Korf, G., Vieregge, P., Heinzow, B., Teichert, H.-M., Schleifenbaum, P., Mösinger, H.-U., Mautner, V.-F., Tatagiba, M., Laute, S., Hazim, W., Gottesleben, A., Schneider, E., Samii, M., Pulst, S. M., Kreitsch, P., Harms, L., Kölmel, H. W., Holzgraefe, M., Lemme, W., Funke, W., Felix, R., Feiten, M., Schiffke, K. A., Friedrich, H.-J., Westphal, H., Ludin, H. P., Müller, B., Ludolph, A. C., Bick, U., Masur, H., Ullrich, K., Grahmann, F., Grehl, H., Claus, D., Neundörfer, B., Glahn, J., Straeten, V., Busse, O., Schneider, Dietmar, Berrouschot, Jörg, Wagner, Armin, Lindenau, Karl-Friedrich, Dorr, J., Schneider, R., Krapf, H., Weiser, B., Widder, B., Kleiser, B., Dürr, A., Klingelhöfer, J., Martin, J., Kujat, C., Lehmann, H., Hofferberth, B., Maier-Hauff, K., Laudahn, D., Madiener, J., Enzensberger, W., Herdt, P., Kalus, P., Helm, E. B., Hajak, G., Sander, D., Schulz-Varszegi, M., Rüther, E., Conrad, B., Braun, J., Glasner, H., Cervos-Navarro, J., Dauch, Wolfgang A., Bauer, Bernhard L., and Schimrigk, K.

Published
1992
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12. Multi-Center Planning Radiosurgery for Intracranial Metastases through Automation (MC-PRIMA)

Author

Chan, M.K.H., primary, Liu, H., additional, Venencia, D., additional, Kadoya, N., additional, Alheet, S., additional, Toutaoui, A., additional, Krayenbuehl, J., additional, Sturt, P., additional, Leung, R.W., additional, Gevaert, T., additional, Valenti, M., additional, Skourou, C., additional, Modolell, I., additional, Martinez, C.O., additional, Farias, R.O., additional, Dorr, J., additional, Hanvey, S., additional, Waldron, J., additional, Grohmann, M., additional, and Sylvia, G., additional

Published
2020
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14. Early mitoxantrone-induced cardiotoxicity in secondary progressive multiple sclerosis

Author

Paul, F., Dorr, J., Wurfel, J., Vogel, H.-P., and Zipp, F.

Subjects
Multiple sclerosis -- Case studies, Multiple sclerosis -- Care and treatment, Multiple sclerosis -- Health aspects, Mitoxantrone hydrochloride -- Research, Heart diseases -- Case studies, Heart diseases -- Health aspects, Health, Psychology and mental health
Published
2007

19. Retirada de implantes mamarios y corrección simultánea con colgajo dermoglandular inferior: técnica de mastopexia con autoprótesis

Author

Rancati, A., Dorr, J., Irigo, M., Peralta, B., Gonzalez, E., Angrigiani, C., Zampieri, A., Scuderi, N., and Nava, M.

Subjects
Breast implant explantation, Prótesis mamarias, Mastopexia, Colgajos mamarios, Mammary flaps, Implantes mamarios, Mastopexy, Retirada de implantes mamarios, Mammary implants
Abstract

Los cirujanos plásticos nos enfrentamos cada vez con más frecuencia en nuestra consulta a pacientes que desean o necesitan retirar sus implantes mamarios. Algunas de estas pacientes rechazan la idea de un reemplazo protésico, pero son exigentes con el resultado cosmético postoperatorio. Describimos la técnica empleada en 68 casos consecutivos y los resultados que hemos obtenido al tratar las secuelas en la mama tras la retirada de los implantes, fundamentalmente una disminución de volumen asociada a ptosis y excedente cutáneo. Esta técnica se basa en la extracción de los implantes y correccion mamaria simultanea con colgajo dermoglandular inferior que denominamos "autoprotesis" asociado a injerto graso simultáneo. Los resultados logran mejorar la forma, proyección y conificacion de la mama tras la retirada de los implantes, con un alto grado de satisfacción por parte de las pacientes. Plastic surgeons are frequently faced during consultation with patients who want or need breast implant explantation. Some of these patients reject the idea of a prosthetic replacement, but are demanding with the postoperative cosmetic result. We describe the technique used in 68 consecutive cases and our results to deal with breast alterations after breast implant explantation, leaving a decreased mammary volume, ptosis and a loosy cutaneous excedent. With this technique of explantation and simultaneous breast correction with de-epithelialized dermoglandular flap, "authoprosthesis", associated with simultaneous fat grafting, we can get a good result regarding the shape, projection and coning of the explanted breast, with high patient satisfaction.

Published
2014

20. Corrección de la mama tuberosa solo con implantes anatómicos

Author

Rancati, A., Gonzalez, E., Dorr, J., Vidal, L., Murias-Pettinari, M., and Irigo, M.

Subjects
Mama tuberosa, Tuberous breast, Aumento mamario, Implantes mamarios, Breast augmentation, Breast implants
Abstract

Las mamas tuberosas, denominadas así por Rees y Aston, y también llamadas hernias del complejo areolar (Bass), Snoopy deformity (Gruber), mamas tubulares (Williams), hipoplasia del polo inferior (Brink) o mamas de base estrecha (Puckett), son una malformacion en el desarrollo del volumen mamario en los cuadrantes inferiores con hernia areolar secundaria (placa areolar y músculo mamilar débiles), areola ancha y protruida (en la mitad de los casos), ascenso del surco submamario, mamas hipotróficas y raramente hipertróficas, con asimetrías en las dos terceras partes de las pacientes. Presentamos la estrategia quirúrgica adecuada para resolver esta patología utilizando solo implantes anatómicos de gel cohesivo sin necesidad de tallar colgajos glandulares. De esta manera, disminuimos la morbilidad quirúrgica, ofreciendo resultados estables y con alta satisfaccion por parte de las pacientes. Tuberous breasts, denominated like this by Rees and Aston, and also called areolar complex hernia by Bass, Snoopy deformity by Gruber, tubular breasts by Williams, inferior pole hypoplasia by Brink, tight base breasts by Puckett, are a malformation of breast with inferior quadrants alteration that produce an areolar herniation and protrusion (in fifty per cent of the cases), and elevation of the infamammary fold; they are rarely hypertrophic and with asymmetries in two thirds of the patients. Authors present the surgical strategy to solve this pathology just using high cohesive silicone gel anatomical implants without needing of glandular flap tailoring. By this way, surgical morbidity is diminished offering stable results and high patient satisfaction.

Published
2013

21. A Binary Genetic Approach to Characterize TRPM5 Cells in Mice

Author

Kusumakshi, S., primary, Voigt, A., additional, Hubner, S., additional, Hermans-Borgmeyer, I., additional, Ortalli, A., additional, Pyrski, M., additional, Dorr, J., additional, Zufall, F., additional, Flockerzi, V., additional, Meyerhof, W., additional, Montmayeur, J.-P., additional, and Boehm, U., additional

Published
2015
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38. Native American technology access: the Gates Foundation in Four Corners.

Author

Gordon AC, Dorr J, and Gordon M

Abstract

The Bill & Melinda Gates Foundation's Native American Access to Technology Program (NAATP) was designed to provide computer and Internet access to Native peoples in the Four Corners area of the USA. Through this multi-year effort, complex packages of hardware, software, installation and training have been made available to 43 tribes in 161 settings. An intensive, collaborative process resulted in a package carefully designed to fit tribal interests, circumstances and political arrangements, including multimedia (graphics-intensive) equipment, language preservation software, and satellite connections to the Internet as necessary. This interim assessment concludes that the program has substantially increased tribal access to computing and information and has often fostered creative use of the technologies. Deeply embedded economic and political realities and their legacies remain, however, with substantial immediate and long-term consequences. [ABSTRACT FROM AUTHOR]

Published
2003
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39. Alemtuzumab in the treatment of multiple sclerosis: patient selection and special considerations

Author

Dörr J and Baum K

Subjects
multiple sclerosis, treatment, safety, efficacy, selection, benefit risk relation, Therapeutics. Pharmacology, RM1-950
Abstract

Jan Dörr,1,2 Karl Baum1 1Multiple Sclerosis Center, Neurology Department, Klinik Hennigsdorf, Hennigsdorf, 2NeuroCure Clinical Research Center, Charité – Universitätsmedizin Berlin, Berlin, Germany Abstract: Multiple sclerosis (MS) is among the most common chronic inflammatory diseases of the central nervous system. Although not curable, the constantly increasing armamentarium of disease-modifying drugs now allows control of disease activity in many patients. The humanized monoclonal antibody alemtuzumab is a powerful drug licensed for the treatment of MS. Upon binding to the CD52 surface protein on CD4+ and CD8+ T cells, B cells, and monocytes, circulating CD52+ cells are eliminated via antibody- and complement-mediated lysis, and a less autoreactive adaptive immune system is reconstituted. The efficacy of alemtuzumab in terms of both clinical and magnetic resonance imaging outcomes has been demonstrated in several phase II/III trials including long-term extensions and follow-up studies. Treatment response to alemtuzumab is strongest as long as active inflammation is the predominant pathophysiological feature, and it is becoming less efficacious in neurodegeneration-dominated later stages of the disease. Thus, the optimal placement of alemtuzumab within treatment algorithms of MS is crucial. The impressive efficacy of alemtuzumab is counteracted by a less favorable safety profile. Besides usually manageable infusion-associated side effects, development of secondary autoimmunity in almost half of treated patients is the most disconcerting risk of alemtuzumab. The high frequency, the delayed occurrence, and the potentially severe course of secondary autoimmune diseases require awareness and a close long-term monitoring of patients treated with alemtuzumab. Biomarkers that would allow prediction of treatment response to alemtuzumab on the one hand and identification of patients at risk for the development of secondary autoimmune diseases on the other are not yet available. Thus, the overall success of alemtuzumab treatment critically depends on the patient selection. The aim of this article is therefore, to characterize the significance of alemtuzumab in the treatment of MS with a focus on the selection of the optimal patient. Keywords: multiple sclerosis, treatment, safety, efficacy, selection, benefit risk relation

Published
2016

41. New Mexico tribal libraries: bridging the digital divide.

Author

Dorr J and Akeroyd R

Abstract

If the phrase 'heartwarming technology' seems like an oxymoron to you, then you'll want to read this article. You'll learn how a computer-donation program from the Bill & Melinda Gates Foundation has been expanding the horizons of Native Americans who live in the remote deserts of the Southwest. [ABSTRACT FROM AUTHOR]

Published
2001

45. Latest JET results in deuterium and deuterium-tritium plasmas

Author

Adams, J. M., Ageladarakis, P., Arshad, S. A., Alper, B., Altmann, H., Andrew, P., Bailey, D., Bainbridge, N., Balet, B., Baranov, Y., Barker, P., Barnsley, R., Baronian, M., Bartlett, D. V., Bell, A. C., Bertolini, E., Bhatnagar, V., Bickley, A. J., Bindslev, H., Blackler, K., Bond, D., Bonicelli, T., Borba, D., Brandon, M., Breger, P., Brelen, H., Brennan, P., Brewerton, W. J., Browne, M. L., Budd, T., Burt, A., Businaro, T., Buzio, M., Caldwell-Nichols, C., Campling, D., Card, P., Challis, C. D., Chankin, A. V., Chiron, D., Christiansen, J., Chuilon, P., Ciric, D., Claesen, R., Clarke, H. E., Clement, S., Coad, J. P., Coffey, I., Conroy, S., Conway, G., Cooper, S., Cordey, J. G., Corrigan, G., Cottrell, G., Cox, M., Cox, S. J., Cusack, R., Davies, N., Davies, S. J., Davis, J. J., de Benedetti, M., de Esch, H., de Haas, J., Deksnis, E., Deliyanakis, N., Dines, A., Dmitrenko, S. L., Dobbing, J., Dolgetta, N., Dorling, S. E., Dorr, J., Doyle, P. G., Duquenoy, H., Edwards, A. M., Edwards, A. W., Egedal, J., Ehrenberg, J., Ekedahl, A., Elevant, T., Ellis, J., Endler, M., Erents, S. K., Ericsson, S., Esposito, B., Eriksson, L. G., Falter, H., Farthing, J. W., Fasoli, A., Fichtmuller, M., Fischer, B., Fishpool, G., Fullard, K., Gadeberg, M., Galbiati, L., Giannella, R., Gibson, A., Gill, R. D., Godden, D., Gondhalekar, A., Goodall, D., Gormezano, C., Gowers, C., Guenther, K., Guo, H., Haigh, A., Haist, B., Hancock, C. J., Harbour, P. J., Hawkes, N. C., Hawkes, N. P., Hemmerich, J. L., Hender, T., Hoekzema, J., Horton, L., How, J., Howman, A., Huart, M., Hughes, T. P., Hurd, F., Huysmans, G., Ingesson, C., Ingram, B., Irving, M., Jacquinot, J., Jaeckel, H., Jaeger, J. F., Jarvis, O. N., Jensen, F., Johnson, M., Jones, E. M., Jones, T. T. C., Junger, J. F., Junique, F., Kaye, A., Keen, B. E., Keilhacker, M., Kerner, W., Kidd, N. G., Knipe, S., Konig, R., Krom, J. G., Kupschus, P., Lasser, R., Last, J. R., Lauro-Taroni, L., Lawson, K., Lennholm, M., Lingertat, J., Lomas, P. J., Loughlin, M., Lovegrove, T., Lowry, C., Maas, A. C., Macklin, B., Maggi, C. F., Mantsinen, M., Marchese, V., Marcus, F., Mart, J., Martin, D., Matthews, G., McBryan, H., McCracken, G., McCullen, P. A., Meigs, A., Middleton, R., Miele, P., Milani, F., Mills, J., Mohanti, R., Monk, R., Morgan, P., Murphy, G., Nave, F., Newbert, G., Nielsen, P., Noll, P., Obert, W., O'Brien, D., Oord, E., Ostrom, R., Ottaviani, M., Papastergiou, S., Parail, V. V., Parkinson, R., Parsons, W., Patel, B., Paynter, A., Perevezentsev, A., Peacock, A., Peacock, N., Pearce, R. J. H., Perry, C., Pick, M. A., Plancoulaine, J., Pogutse, O., Prentice, R., Puppin, S., Radford, G., Reichle, R., Riccardo, V., Righi, E., Rimini, F., Rolfe, A., Roquemore, L., Ross, R. T., Rossi, A., Rossi, L., Sadler, G., Saibene, G., Salisbury, M., Santagiustina, A., Sartori, F., Saunders, R., Schild, P., Schmid, M., Schmidt, V., Schokker, B., Schunke, B., Scibile, L., Scott, S. M., Sharapov, S., Sibley, A., Simonini, R., Sips, A. C. C., Smeulders, P., Smith, P., Smith, R., Soldner, F., Spence, J., Springmann, E., Stagg, R., Stamp, M., Stangeby, P., Start, D. F., Stork, D., Stott, P. E., Strachen, P., Stubberfield, P., Summers, D., Svensson, L., Svensson, P., Tabasso, A., Tabellini, M., Tait, J., Tanga, A., Taroni, A., Terella, C., Thomas, P. R., Thomsen, K., Traneus, E., Tubbing, B., Twyman, P., Ul'Haq, Y., Vadgama, A., van Belle, P., van der Linden, R., Vlases, G. C., von Hellermann, M., Wade, T., Walton, R., Ward, D., Watkins, M. L., Watkins, N., Watson, M. J., Wheatley, M., Wilson, D., Winkel, T., Young, D., Young, I. D., Yu, Q., Zastrow, K. D., Zhang, W., Zornig, N., and Zwingmann, W.

Subjects
Physics::Plasma Physics, JET, ITER
Abstract

All major JET systems have been fully commissioned for D-T and the DTE1 series of experiments has started with the D-T fuel mixture and operating conditions foreseen for ITER. In the area of ITER physics, significant results have been produced in both D-D and D-T. In D-D, the LH threshold power database has been extended, the bounds on edge-electron temperature and density in ELMy H-modes have been defined and the advantages of Types I and III ELMy discharges have been compared. In D-T plasmas, the isotope effect on H-mode threshold power and transport has been determined so that a more accurate assessment can be made of the ignition margin and heating requirements for ITER. Trace tritium experiments have provided first particle transport measurements and an assessment of the ITER reference ion-cyclotron resonance-frequency heating scenarios has been started, In the area of fusion performance, record D-D neutron yields have been obtained by controlling the plasma and current profiles in hot ion ELM-free H-modes and optimized shear modes. In D-T, internal transport barriers have been readily established in optimized shear discharges and Alfven eigenmodes have been observed.

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