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202 results on '"Dou, Xiaoguang"'

1. Role of Early On-Treatment Serum HBV RNA Declines in Predicting Hepatocellular Carcinoma Risk in Patients With Chronic Hepatitis B

Author

Liu, Shi, Wong, Grace Lai-Hung, Fan, Rong, Niu, Junqi, Ma, Hong, Liang, Wanying, Lu, Xingyu, Xie, Jianping, Shang, Jia, Xie, Dongying, Liu, Yali, Zhou, Bin, Xie, Qing, Peng, Jie, Gao, Hongbo, Rao, Huiying, Chen, Jinjun, Sheng, Jifang, Shen, Sheng, Yang, Song, Dou, Xiaoguang, Zhang, Zhengang, Wong, Vincent Wai-Sun, Hou, Jinlin, and Sun, Jian

Published
2024
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2. Novel, high accuracy models for hepatocellular carcinoma prediction based on longitudinal data and cell-free DNA signatures

Author

Fan, Rong, Chen, Lei, Zhao, Siru, Yang, Hao, Li, Zhengmao, Qian, Yunsong, Ma, Hong, Liu, Xiaolong, Wang, Chuanxin, Liang, Xieer, Bai, Jian, Xie, Jianping, Fan, Xiaotang, Xie, Qing, Hao, Xin, Wang, Chunying, Yang, Song, Gao, Yanhang, Bai, Honglian, Dou, Xiaoguang, Liu, Jingfeng, Wu, Lin, Jiang, Guoqing, Xia, Qi, Zheng, Dan, Rao, Huiying, Xia, Jie, Shang, Jia, Gao, Pujun, Xie, Dongying, Yu, Yanlong, Yang, Yongfeng, Gao, Hongbo, Liu, Yali, Sun, Aimin, Jiang, Yongfang, Yu, Yanyan, Niu, Junqi, Sun, Jian, Wang, Hongyang, and Hou, Jinlin

Published
2023
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4. WED-412 Functional cure and prediction analysis of pegylated interferon alpha-2b in HBeAg negative chronic hepatitis B patients with normal ALT (Ice-breaking Project in China): an interim analysis update

Author

Zhang, Chong, primary, Zeng, Dawu, additional, Cai, Dachuan, additional, Xue, Xiulan, additional, Zhang, Lingyi, additional, Song, Baojun, additional, Gao, Yufeng, additional, Huang, Yan, additional, Shang, Jia, additional, Wu, Xiaofeng, additional, Zhang, Ying, additional, Jin, Hua, additional, Chen, Hui, additional, Tang, Hong, additional, Lu, Xiaobo, additional, Guan, Yujuan, additional, Min, Feng, additional, Xu, Liang, additional, Li, Gang, additional, Wang, Zhenguang, additional, and Dou, Xiaoguang, additional

Published
2024
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5. LBP-037 Role of early on-treatment serum hepatitis B virus RNA declines in the prediction of hepatocellular carcinoma risk in patients with chronic hepatitis B

Author

Liu, Shi, primary, Wong, Grace Lai-Hung, additional, Fan, Rong, additional, Niu, Junqi, additional, Ma, Hong, additional, Liang, Wanying, additional, Lu, Xingyu, additional, Xie, Jianping, additional, Shang, Jia, additional, Xie, Dong-Ying, additional, Liu, Yali, additional, Zhou, Bin, additional, Xie, Qing, additional, Peng, Jie, additional, Gao, Hongbo, additional, Rao, Huiying, additional, Chen, Jinjun, additional, Sheng, Jifang, additional, Shen, Sheng, additional, Yang, Song, additional, Dou, Xiaoguang, additional, Zhang, Zhengang, additional, Wong, Vincent Wai-Sun, additional, Hou, Jinlin, additional, and Sun, Jian, additional

Published
2024
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10. Association Between Negative Results From Tests for HBV DNA and RNA and Durability of Response After Discontinuation of Nucles(t)ide Analogue Therapy

Author

Wan, Mobin, Chen, Shijun, Yu, Yanyan, Ma, Hong, Cheng, Jun, Zhang, Hongfei, Liu, Huimin, Gao, Zhiliang, Dou, Xiaoguang, Fan, Rong, Zhou, Bin, Xu, Min, Tan, Deming, Niu, Junqi, Wang, Hao, Ren, Hong, Chen, Xinyue, Wang, Maorong, Ning, Qin, Shi, Guangfeng, Sheng, Jifang, Tang, Hong, Bai, Xuefan, Liu, Shi, Lu, Fengmin, Peng, Jie, Sun, Jian, Xie, Qing, and Hou, Jinlin

Published
2020
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14. Efficacy and prediction analysis of pegylated interferon alpha-2b in treatment-naive HBeAg negative chronic hepatitis B patients with normal ALT: a multicenter real-world study (Ice-breakting Project in China)-Interim analysis

Author

Zhang, Chong, primary, Zeng, Da-Wu, additional, Cai, Da-Chuan, additional, Xue, Xiu-Lan, additional, Zhang, Ling-Yi, additional, Song, Bao-Jun, additional, Gao, Yu-Feng, additional, Huang, Yan, additional, Shang, Jia, additional, Wu, Xiao-Feng, additional, Zhang, Ying, additional, Jin, Hua, additional, Chen, Hui, additional, Tang, Hong, additional, Lu, Xiaobo, additional, Guan, Yujuan, additional, Min, Feng, additional, Xu, Liang, additional, Li, Gang, additional, Wang, Zhen-Guang, additional, and Dou, Xiaoguang, additional

Published
2023
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15. Novel, high accuracy prediction models of hepatocellular carcinoma based on longitudinal data and cell-free DNA signatures

Author

Fan, Rong, primary, Chen, Lei, additional, Yang, Hao, additional, Zhao, Siru, additional, Li, Zhengmao, additional, Qian, Yunsong, additional, Ma, Hong, additional, Liu, Jingfeng, additional, Niu, Junqi, additional, Wang, Chuanxin, additional, Bai, Jian, additional, Xie, Jianping, additional, Fan, Xiaotang, additional, Xie, Qing, additional, Wang, Chunying, additional, Yang, Song, additional, Bai, Honglian, additional, Dou, Xiaoguang, additional, Wu, Lin, additional, Jiang, Guoqing, additional, Xia, Qi, additional, Zheng, Dan, additional, Rao, Huiying, additional, Xia, Jie, additional, Shang, Jia, additional, Gao, Pujun, additional, Xie, Dong-Ying, additional, Yu, Yanlong, additional, Yang, Yongfeng, additional, Gao, Hongbo, additional, Liu, Yali, additional, Sun, Aimin, additional, Jiang, Yongfang, additional, Yu, Yan-Yan, additional, Sun, Jian, additional, Wang, Hong-Yang, additional, and Hou, Jinlin, additional

Published
2023
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16. High accuracy model for HBsAg loss based on longitudinal trajectories of serum qHBsAg throughout long-term antiviral therapy

Author

Fan, Rong, Zhao, Siru, Niu, Junqi, Ma, Hong, Xie, Qing, Yang, Song, Xie, Jianping, Dou, Xiaoguang, Shang, Jia, Rao, Huiying, Xia, Qi, Liu, Yali, Yang, Yongfeng, Gao, Hongbo, Sun, Aimin, Liang, Xieer, Yin, Xueru, Jiang, Yongfang, Yu, Yanyan, Sun, Jian, Naoumov, Nikolai V, and Hou, Jinlin

Abstract

ObjectiveHepatitis B surface antigen (HBsAg) loss is the optimal outcome for patients with chronic hepatitis B (CHB) but this rarely occurs with currently approved therapies. We aimed to develop and validate a prognostic model for HBsAg loss on treatment using longitudinal data from a large, prospectively followed, nationwide cohort.DesignCHB patients receiving nucleos(t)ide analogues as antiviral treatment were enrolled from 50 centres in China. Quantitative HBsAg (qHBsAg) testing was prospectively performed biannually per protocol. Longitudinal discriminant analysis algorithm was used to estimate the incidence of HBsAg loss, by integrating clinical data of each patient collected during follow-up.ResultsIn total, 6792 CHB patients who had initiated antiviral treatment 41.3 (IQR 7.6–107.6) months before enrolment and had median qHBsAg 2.9 (IQR 2.3–3.3) log10IU/mL at entry were analysed. With a median follow-up of 65.6 (IQR 51.5–84.7) months, the 5-year cumulative incidence of HBsAg loss was 2.4%. A prediction model integrating all qHBsAg values of each patient during follow-up, designated GOLDEN model, was developed and validated. The AUCs of GOLDEN model were 0.981 (95% CI 0.974 to 0.987) and 0.979 (95% CI 0.974 to 0.983) in the training and external validation sets, respectively, and were significantly better than those of a single qHBsAg measurement. GOLDEN model identified 8.5%–10.4% of patients with a high probability of HBsAg loss (5-year cumulative incidence: 17.0%–29.1%) and was able to exclude 89.6%–91.5% of patients whose incidence of HBsAg loss is 0. Moreover, the GOLDEN model consistently showed excellent performance among various subgroups.ConclusionThe novel GOLDEN model, based on longitudinal qHBsAg data, accurately predicts HBsAg clearance, provides reliable estimates of functional hepatitis B virus (HBV) cure and may have the potential to stratify different subsets of patients for novel anti-HBV therapies.

Published
2024
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17. Impact of nonalcoholic fatty liver disease status change on antiviral efficacy of nucleos(t)ide analogues in HBeAg‐positive chronic hepatitis B

Author

Tang, Yanhua, primary, Fan, Rong, additional, Lan, Zhixian, additional, Xie, Qing, additional, Zhang, Jiping, additional, Liang, Xieer, additional, Wang, Hao, additional, Tan, Deming, additional, Cheng, Jun, additional, Chen, Shijun, additional, Ning, Qin, additional, Bai, Xuefan, additional, Xu, Min, additional, Chen, Xinyue, additional, Niu, Junqi, additional, Shi, Junping, additional, Ren, Hong, additional, Gao, Zhiliang, additional, Wang, Maorong, additional, Dou, Xiaoguang, additional, Hou, Jinlin, additional, and Sun, Jian, additional

Published
2023
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18. OS-033 - Novel, high accuracy prediction models of hepatocellular carcinoma based on longitudinal data and cell-free DNA signatures

Author

Fan, Rong, Chen, Lei, Yang, Hao, Zhao, Siru, Li, Zhengmao, Qian, Yunsong, Ma, Hong, Liu, Jingfeng, Niu, Junqi, Wang, Chuanxin, Bai, Jian, Xie, Jianping, Fan, Xiaotang, Xie, Qing, Wang, Chunying, Yang, Song, Bai, Honglian, Dou, Xiaoguang, Wu, Lin, Jiang, Guoqing, Xia, Qi, Zheng, Dan, Rao, Huiying, Xia, Jie, Shang, Jia, Gao, Pujun, Xie, Dong-Ying, Yu, Yanlong, Yang, Yongfeng, Gao, Hongbo, Liu, Yali, Sun, Aimin, Jiang, Yongfang, Yu, Yan-Yan, Sun, Jian, Wang, Hong-Yang, and Hou, Jinlin

Published
2023
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19. Association between nonalcoholic fatty liver disease status changes and antiviral efficacy in chronic hepatitis B

Author

Tang, Yanhua, primary, Fan, Rong, additional, Xie, Qing, additional, Zhang, Jiping, additional, Liang, Xieer, additional, Wang, Hao, additional, Tan, Deming, additional, Cheng, Jun, additional, Chen, Shijun, additional, Ning, Qin, additional, Bai, Xuefan, additional, Xu, Min, additional, Chen, Xinyue, additional, Niu, Junqi, additional, Shi, Junping, additional, Ren, Hong, additional, Gao, Zhiliang, additional, Wang, Maorong, additional, Dou, Xiaoguang, additional, Hou, Jinlin, additional, and Sun, Jian, additional

Published
2022
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20. Association of baseline vitamin D level with genetic determinants and virologic response in patients with chronic hepatitis B

Author

Yu, Rui, Tan, Deming, Ning, Qin, Niu, Junqi, Bai, Xuefan, Chen, Shijun, Cheng, Jun, Yu, Yanyan, Wang, Hao, Xu, Min, Shi, Guangfeng, Wan, Mobin, Chen, Xinyue, Tang, Hong, Sheng, Jifang, Dou, Xiaoguang, Shi, Junping, Ren, Hong, Wang, Maorong, Zhang, Hongfei, Gao, Zhiliang, Chen, Chengwei, Ma, Hong, Jia, Jidong, Hou, Jinlin, Xie, Qing, and Sun, Jian

Published
2018
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21. Management Algorithm for Prevention of Mother-to-child Transmission of Hepatitis B Virus (2022)

Author

Liu, Zhihua, primary, Chen, Zhongdan, additional, Cui, Fuqiang, additional, Ding, Yang, additional, Gao, Yunfei, additional, Han, Guorong, additional, Jia, Jidong, additional, Li, Jie, additional, Li, Zengde, additional, Liu, Yingxia, additional, Mao, Qing, additional, Wang, Ailing, additional, Wang, Wei, additional, Wei, Lai, additional, Xia, Jianhong, additional, Xie, Qing, additional, Yang, Xizhong, additional, Yin, Xueru, additional, Zhang, Hua, additional, Zhang, Liaoyun, additional, Zhang, Wenhong, additional, Zhuang, Hui, additional, Dou, Xiaoguang, additional, and Hou, Jinlin, additional

Published
2022
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22. Global multi-stakeholder endorsement of the MAFLD definition

Author

Méndez-Sánchez, Nahum, primary, Bugianesi, Elisabetta, additional, Gish, Robert G, additional, Lammert, Frank, additional, Tilg, Herbert, additional, Nguyen, Mindie H, additional, Sarin, Shiv K, additional, Fabrellas, Núria, additional, Zelber-Sagi, Shira, additional, Fan, Jian-Gao, additional, Shiha, Gamal, additional, Targher, Giovanni, additional, Zheng, Ming-Hua, additional, Chan, Wah-Kheong, additional, Vinker, Shlomo, additional, Kawaguchi, Takumi, additional, Castera, Laurent, additional, Yilmaz, Yusuf, additional, Korenjak, Marko, additional, Spearman, C Wendy, additional, Ungan, Mehmet, additional, Palmer, Melissa, additional, El-Shabrawi, Mortada, additional, Gruss, Hans-Juergen, additional, Dufour, Jean-François, additional, Dhawan, Anil, additional, Wedemeyer, Heiner, additional, George, Jacob, additional, Valenti, Luca, additional, Fouad, Yasser, additional, Romero‐Gomez, Manuel, additional, Eslam, Mohammed, additional, Abate, Maria Lorena, additional, Abbas, Bahaa, additional, Abbassy, Ahmed Amr, additional, Abd El Ghany, Waleed, additional, Abd Elkhalek, Amira, additional, Abd ElMajeed, Emad, additional, Abdalgaber, Mohammad, additional, AbdAllah, Mohamed, additional, Abdallah, Marwa, additional, Abdallah, Nourhan, additional, Abdelaleem, Shereen, additional, Abdelghani, Yasser, additional, Abdelghany, Wael, additional, Abdelhalim, Safaa Mohamed, additional, Abdelhamid, Wafaa, additional, Abdelhamid, Nehal, additional, Abdelkader, Nadia A., additional, Abdelkreem, Elsayed, additional, Abdelmohsen, Aly Mohamed, additional, Abdelrahman, Awny Ali, additional, Abd-elsalam, Sherief M, additional, Abdeltawab, Doaa, additional, Abduh, Abdulbaset, additional, Abdulhakam, Nada, additional, Abdulla, Maheeba, additional, Abedpoor, Navid, additional, Abenavoli, Ludovico, additional, Åberg, Fredrik, additional, Ablack, Omala, additional, Abo elftouh, Mostafa, additional, Abo-Amer, Yousry Esam-Eldin, additional, Aboubkr, Ashraf, additional, Aboud, Alaa, additional, Abouelnaga, Amr M., additional, Aboufarrag, Galal A., additional, Aboutaleb, Ashraf, additional, Abundis, Leticia, additional, Adalı, Gupse, additional, Adames, Enrique, additional, Adams, Leon, additional, Adda, Danjuma, additional, Adel, Noor, additional, Adel, Nada, additional, Adel Sayed, Muhammad, additional, Afaa, Taiba Jibril, additional, Afredj, Nawal, additional, Aghayeva, Gulnara, additional, Aghemo, Alessio, additional, Aguilar-Salinas, Carlos A., additional, Ahlenstiel, Golo, additional, Ahmady, Walid, additional, Ahmed, Wafaa, additional, Ahmed, Amira, additional, Ahmed, Samah Nasser, additional, Ahmed, Heba Mostafa, additional, Ahmed, Rasha, additional, Aigner, Elmar, additional, Akarsu, Mesut, additional, Akroush, Maisam, additional, Akyuz, Umit, additional, Al Mahtab, Mamun, additional, Al Qadiri, Tahani, additional, Al Rawahi, Yusriya, additional, AL rubaee, Razzaq, additional, Al Saffar, Muna, additional, Alam, Shahinul, additional, Al-Ani, Zaid, additional, Albillos, Agustín, additional, Alboraie, Mohamed, additional, Al-Busafi, Said, additional, Al-Emam, Mohamed, additional, Alharthi, Jawaher, additional, Ali, Kareem, additional, Ali, Basma Abdelmoez, additional, Ali, Mohammad, additional, Ali, Raja Affendi Raja, additional, Alisi, Anna, additional, AL-Khafaji, Ali Raad, additional, Alkhatry, Maryam, additional, Aller, Rocio, additional, Almansoury, Yahya, additional, Al-Naamani, Khalid, additional, Alnakeeb, Alaa, additional, Alonso, Anna, additional, Alqahtani, Saleh A., additional, Alrabadi, Leina, additional, Alswat, Khalid, additional, Altaher, Mahir, additional, Altamimi, Turki, additional, Altamirano, Jose, additional, Alvares-da-Silva, Mario R., additional, Aly, Elsragy Adel M., additional, Alzahaby, Amgad, additional, Alzamzamy, Ahmed, additional, Amano, Keisuke, additional, Amer, Maysa A., additional, Amin, Mona A., additional, Amin, Sayed A., additional, Amir, Ashraf A., additional, Ampuero, Javier, additional, Anas, Noha, additional, Andreone, Pietro, additional, Andriamandimby, Soa Fy, additional, Anees, Mahmoud, additional, Angela, Peltec, additional, Antonios, Manal, additional, Arafat, Wael, additional, Araya, Jose Moreno, additional, Armendariz-Borunda, Juan, additional, Armstrong, Matthew J., additional, Ashktorab, Hassan, additional, Aspichueta, Patricia, additional, Assal, Fathia, additional, Atef, Mira, additional, Attia, Dina, additional, Atwa, Hoda, additional, Awad, Reham, additional, Awad, Mohyeldeen Abd Elaziz, additional, Awny, Sally, additional, Awolowo, Obafemi, additional, Awuku, Yaw Asante, additional, Ayada, Ibrahim, additional, Aye, Than Than, additional, Ayman, Sherif, additional, Ayman, Hedy, additional, Ayoub, Hesham, additional, Azmy, Hosny M., additional, Babaran, Romiro P., additional, Badreldin, Omneya, additional, Badry, Ahmed, additional, Bahçecioğlu, İbrahim Halil, additional, Bahour, Amira, additional, Bai, Jiajia, additional, Balaban, Yasemin, additional, Balasubramanyam, Muthuswamy, additional, Bamakhrama, Khaled, additional, Banales, Jesus M, additional, Bangaru, Babu, additional, Bao, Jianfeng, additional, Barahona, Jorge Suazo, additional, Barakat, Salma, additional, Barbalho, Sandra Maria, additional, Barbra, Bikwa, additional, Barranco, Beatriz, additional, Barrera, Francisco, additional, Baumann, Ulrich, additional, Bazeed, Shamardan, additional, Bech, Eva, additional, Benayad, Aourarh, additional, Benesic, Andreas, additional, Bernstein, David, additional, Bessone, Fernando, additional, Birney, Susie, additional, Bisseye, Cyrille, additional, Blake, Martin, additional, Bobat, Bilal, additional, Bonfrate, Leonilde, additional, Bordin, Dmitry S, additional, Bosques-Padilla, Francisco, additional, Boursier, Jerome, additional, Boushab, Boushab Mohamed, additional, Bowen, David, additional, Bravo, Patricia Medina, additional, Brennan, Paul N, additional, Bright, Bisi, additional, Broekaert, Ilse, additional, Buque, Xabier, additional, Burgos-Santamaría, Diego, additional, Burman, Julio, additional, Busetto, Luca, additional, Byrne, Chris D., additional, Cabral-Prodigalidad, Patricia Anne I., additional, Cabrera-Alvarez, Guillermo, additional, Cai, Wei, additional, Cainelli, Francesca, additional, Caliskan, Ali Riza, additional, Canbay, Ali, additional, Cano-Contreras, Ana, additional, Cao, Hai-Xia, additional, Cao, Zhujun, additional, Carrion, Andres, additional, Carubbi, Francesca, additional, Casanovas, Teresa, additional, Castellanos Fernández, Marlen Ivón, additional, Chai, Jin, additional, Chan, Siew Pheng, additional, Charatcharoenwitthaya, Phunchai, additional, Chavez-Tapia, Norberto, additional, Chayama, Kazuaki, additional, Chen, Jinjun, additional, Chen, Lin, additional, Chen, Zhong-Wei, additional, Chen, Huiting, additional, Chen, Sui-Dan, additional, Chen, Qiang, additional, Chen, Yaxi, additional, Chen, Gang, additional, Chen, En-Quang, additional, Chen, Fei, additional, Chen, Pei-Jer, additional, Cheng, Robert, additional, Cheng, Wendy, additional, Chieh, Jack Tan Wei, additional, Chokr, Imad, additional, Cholongitas, Evangelos, additional, Choudhury, Ashok, additional, Chowdhury, Abhijit, additional, Chukwudike, Evaristus Sunday, additional, Ciardullo, Stefano, additional, Clayton, Michelle, additional, Clement, Karine, additional, Cloa, Marie Michelle, additional, Coccia, Cecilia, additional, Collazos, Cristina, additional, Colombo, Massimo, additional, Cosar, Arif Mansur, additional, Cotrim, Helma Pinchemel, additional, Couillerot, Joris, additional, Coulibaly, Alioune, additional, Crespo, Gonzalo, additional, Crespo, Javier, additional, Cruells, Maria, additional, Cua, Ian Homer Y., additional, Dabbous, Hesham K., additional, Dalekos, George N, additional, D'Alia, Patricia, additional, Dan, Li, additional, Dao, Viet Hang, additional, Darwish, Mostafa, additional, Datz, Christian, additional, Davalos-Moscol, Milagros B, additional, Dawoud, Heba, additional, de Careaga, Blanca Olaechea, additional, de Knegt, Robert, additional, de Ledinghen, Victor, additional, de Silva, Janaka, additional, Debzi, Nabil, additional, Decraecker, Marie, additional, Del Pozo, Elvira, additional, Delgado, Teresa C, additional, Delgado-Blanco, Manuel, additional, Dembiński, Łukasz, additional, Depina, Adilson, additional, Derbala, Moutaz, additional, Desalegn, Hailemichael, additional, Desbois-Mouthon, Christèle, additional, Desoky, Mahmoud, additional, Dev, Anouk, additional, Di Ciaula, Agostino, additional, Diago, Moisés, additional, Diallo, Ibrahima, additional, Díaz, Luis Antonio, additional, Dirchwolf, Melisa, additional, Dongiovanni, Paola, additional, Dorofeyev, Andrriy, additional, Dou, Xiaoguang, additional, Douglas, Mark W., additional, Doulberis, Michael, additional, Dovia, Cecil K., additional, Doyle, Adam, additional, Dragojević, Ivana, additional, Drenth, Joost PH, additional, Duan, Xuefei, additional, Dulskas, Audrius, additional, Dumitrascu, Dan L, additional, Duncan, Oliver, additional, Dusabejambo, Vincent, additional, Dwawhi, Rev. Shem N.A., additional, Eiketsu, Sho, additional, El Amrousy, Doaa, additional, El Deeb, Ahmed, additional, El Deriny, Ghada, additional, El Din, Hesham Salah, additional, El Kamshishy, Salwa, additional, El Kassas, Mohamed, additional, El Raziky, Maissa, additional, Elagamy, Osama A, additional, Elakel, Wafaa, additional, Elalfy, Dina, additional, Elaraby, Hanaa, additional, ElAwady, Heba, additional, Elbadawy, Reda, additional, Eldash, Hanaa Hassan, additional, Eldefrawy, Manal S., additional, Elecharri, Carol Lezama, additional, Elfaramawy, Amel, additional, Elfatih, Mohammed, additional, Elfiky, Mahmoud, additional, Elgamsy, Mohamed, additional, Elgendy, Mohamed, additional, El-Guindi, Mohamed A., additional, Elhussieny, Nagi, additional, Eliwa, Ahmed Maher, additional, Elkabbany, Zeineb, additional, El-Khayat, Hesham, additional, El-Koofy, Nehal M., additional, Elmetwalli, Alaa, additional, Elrabat, Amr, additional, El-Raey, Fathiya, additional, Elrashdy, Fatma, additional, Elsahhar, Medhat, additional, Elsaid, Esraa M., additional, Elsayed, Shimaa, additional, Elsayed, Hany, additional, Elsayed, Aly, additional, Elsayed, Amr M., additional, Elsayed, Hamdy, additional, El-Serafy, Magdy, additional, Elsharkawy, Ahmed M., additional, Elsheemy, Reem Yehia, additional, Elshemy, Eman Elsayed, additional, Elsherbini, Sara, additional, Eltoukhy, Naglaa, additional, Elwakil, Reda, additional, Emad, Ola, additional, Emad, Shaimaa, additional, Embabi, Mohamed, additional, Ergenç, Ilkay, additional, Ermolova, Tatiana, additional, Esmat, Gamal, additional, Esmat, Doaa M., additional, Estupiñan, Enrique Carrera, additional, Ettair, Said, additional, Eugen, Tcaciuc, additional, Ezz-Eldin, Mohammed, additional, Falcón, Lidia Patricia Valdivieso, additional, Fan, Yu-Chen, additional, Fandari, Samah, additional, Farag, Mahmoud, additional, Farahat, Taghreed Mohamed, additional, Fares, Eman M., additional, Fares, Michael, additional, Fassio, Eduardo, additional, Fathy, Hayam, additional, Fathy, Dina, additional, Fathy, Wael, additional, Fayed, Soheir, additional, Feng, Dan, additional, Feng, Gong, additional, Fernández-Bermejo, Miguel, additional, Ferreira, Cristina Targa, additional, Ferrer, Javier Díaz, additional, Forbes, Alastair, additional, Fouad, Rabab, additional, Fouad, Hanan M., additional, Frisch, Tove, additional, Fujii, Hideki, additional, Fukunaga, Shuhei, additional, Fukunishi, Shinya, additional, Fulya, Hacer, additional, Furuhashi, Masato, additional, Gaber, Yasmine, additional, Galang, Augusto Jose G., additional, Gallardo, Jacqueline Cordova, additional, Galloso, Rocío, additional, Gamal, Mahmoud, additional, Gamal, Reham, additional, Gamal, Hadeel, additional, Gan, Jian, additional, Ganbold, Anar, additional, Gao, Xin, additional, Garas, George, additional, Garba, Tony, additional, García-Cortes, Miren, additional, García-Monzón, Carmelo, additional, García-Samaniego, Javier, additional, Gastaldelli, Amalia, additional, Gatica, Manuel, additional, Gatley, Elizabeth, additional, Gegeshidze, Tamar, additional, Geng, Bin, additional, Ghazinyan, Hasmik, additional, Ghoneem, Salma, additional, Giacomelli, Luca, additional, Giannelli, Gianluigi, additional, Giannini, Edoardo G., additional, Giefer, Matthew, additional, Ginès, Pere, additional, Girala, Marcos, additional, Giraudi, Pablo J, additional, Goh, George Boon-Bee, additional, Gomaa, Ahmed Ali, additional, Gong, Benbingdi, additional, Gonzales, Dina Hilda C., additional, Gonzalez, Humberto C., additional, Gonzalez-Huezo, Maria Saraí, additional, Graupera, Isabel, additional, Grgurevic, Ivica, additional, Grønbæk, Henning, additional, Gu, Xuelian, additional, Guan, Lin, additional, Gueye, Ibrahima, additional, Guingané, Alice Nanelin, additional, Gul, Ozen Oz, additional, Gul, Cuma Bulent, additional, Guo, Qing, additional, Gupta, Pramendra Prasad, additional, Gurakar, Ahmet, additional, Gutierrez, Juan Carlos Restrepo, additional, Habib, Ghada, additional, Hafez, Azaa, additional, Hagman, Emilia, additional, Halawa, Eman, additional, Hamdy, Osama, additional, Hamed, Abd Elkhalek, additional, Hamed, Dina H., additional, Hamid, Saeed, additional, Hamoudi, Waseem, additional, Han, Yu, additional, Haridy, James, additional, Haridy, Hanan, additional, Harris, David C H Harris, additional, Hart, Michael, additional, Hasan, Fuad, additional, Hashim, Almoutaz, additional, Hassan, Israa, additional, Hassan, Ayman, additional, Hassan, Essam Ali, additional, Hassan, Adel Ahmed, additional, Hassan, Magda Shehata, additional, Hassanin, Fetouh, additional, Hassnine, Alshymaa, additional, Haukeland, John Willy, additional, Hawal, Amr Ismael M., additional, He, Jinfan, additional, He, Qiong, additional, He, Yong, additional, He, Fang-Ping, additional, Hegazy, Mona, additional, Hegazy, Adham, additional, Henegil, Osama, additional, Hernández, Nelia, additional, Hernández-Guerra, Manuel, additional, Higuera-de-la-Tijera, Fatima, additional, Hindy, 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Naomi F., additional, Lankarani, Kamran Bagheri, additional, Lanthier, Nicolas, additional, Lapshyna, Kateryna, additional, Lashen, Sameh A., additional, Laure, Konang Nguieguia Justine, additional, Lazebnik, Leonid, additional, Lebrec, Didier, additional, Lee, Samuel S., additional, Lee, Way Seah, additional, Lee, Yeong Yeh, additional, Leeming, Diana Julie, additional, Leite, Nathalie Carvalho, additional, Leon, Roberto, additional, Lesmana, Cosmas Rinaldi Adithya, additional, Li, Junfeng, additional, Li, Qiong, additional, Li, Jun, additional, Li, Yang-Yang, additional, Li, Yufang, additional, Li, Lei, additional, Li, Min, additional, li, Yiling, additional, Liang, Huiqing, additional, Lijuan, Tang, additional, Lim, Seng Gee, additional, Lim, Lee-Ling, additional, Lin, Shumei, additional, Lin, Han-Chieh, additional, Lin, Rita, additional, Lithy, Rania, additional, Liu, Yaru, additional, Liu, Yuanyuan, additional, Liu, Xin, additional, Liu, Wen-Yue, additional, Liu, Shourong, 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Hala Hussien, additional, Mansouri, Abdellah, additional, Mantovani, Alessandro, additional, Mao, Jun qian, additional, Maramag, Flor, additional, Marchesini, Giulio, additional, Marcus, Claude, additional, Marinho, Rui António Rocha Tato, additional, Martinez-Chantar, Maria L, additional, Martins, Antonieta A. Soares, additional, Marwan, Rana, additional, Mason, Karen Frances, additional, Masoud, Ghadeer, additional, Massoud, Mohamed Naguib, additional, Matamoros, Maria Amalia, additional, Mateos, Rosa Martín, additional, Mawed, Asmaa, additional, Mbanya, Jean Claude, additional, Mbendi, Charles, additional, McColaugh, Lone, additional, McLeod, Duncan, additional, Medina, Juan Francisco Rivera, additional, Megahed, Ahmed, additional, Mehrez, Mai, additional, Memon, Iqbal, additional, Merat, Shahin, additional, Mercado, Randy, additional, Mesbah, Ahmed, additional, Meskini, Taoufik, additional, Metwally, Mayada, additional, Metwaly, Rasha, additional, Miao, Lei, additional, Micah, Eileen, additional, Miele, Luca, additional, Milivojevic, Vladimir, additional, Milovanovic, Tamara, additional, Mina, Yvonne L., additional, Mishkovik, Milan, additional, Mishriki, Amal, additional, Mitchell, Tim, additional, Mohamed, Alshaimaa, additional, Mohamed, Mona, additional, Mohamed, Sofain, additional, Mohammed, Shady, additional, Mohammed, Ahmed, additional, Mohan, Viswanathan, additional, Mohie, Sara, additional, Mokhtar, Aalaa, additional, Moniem, Reham, additional, Montilla, Mabel Segura, additional, Morales, Jose Antonio Orozco, additional, Morata, María María Sánchez, additional, Moreno-Planas, Jose Maria, additional, Morise, Silvia, additional, Mosaad, Sherif, additional, Moselhy, Mohamed, additional, Mostafa, Alaa Mohamed, additional, Mostafa, Ebraheem, additional, Mouane, Nezha, additional, Mousa, Nasser, additional, Moustafa, Hamdy Mahfouz, additional, Msherif, Abeer, additional, Muller, Kate, additional, Munoz, Christopher, additional, Muñoz-Urribarri, Ana Beatriz, additional, Murillo, Omar Alfaro, additional, Mustapha, Feisul Idzwan, additional, Muzurović, Emir, additional, Nabil, Yehia, additional, Nafady, Shaymaa, additional, Nagamatsu, Ayu, additional, Nakajima, Atsushi, additional, Nakano, Dan, additional, Nan, Yuemin, additional, Nascimbeni, Fabio, additional, Naseef, Mirella S., additional, Nashat, Nagwa, additional, Natalia, Taran, additional, Negro, Francesco, additional, Nersesov, Alexander V., additional, Neuman, Manuela, additional, Ng'wanasayi, Masolwa, additional, Ni, Yan, additional, Nicoll, Amanda, additional, Niizeki, Takashi, additional, Nikolova, Dafina, additional, Ningning, Wang, additional, Niriella, Madunil, additional, Nogoibaeva, K.A, additional, Nordien, Rozeena, additional, O Sullivan, Catherine, additional, O'Beirne, James, additional, Obekpa, Solomon, additional, Ocama, Ponsiano, additional, Ochwoto, Missiani, additional, Ogolodom, Michael Promise, additional, Ojo, Olusegun, additional, Okrostsvaridze, Nana, additional, Oliveira, Claudia P., additional, Omaña, Raul Contreras, additional, Omar, Omneya M., additional, Omar, Hanaa, additional, Omar, Mabroka, additional, Omran, Salma, additional, Omran, Reham, additional, Osman, Marian Muse, additional, Owise, Nevin, additional, Owusu-Ansah, Theobald, additional, Padilla- Machaca, P. 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2022
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23. Global multi-stakeholder endorsement of the MAFLD definition

Author

Abate, Maria Lorena, Abbas, Bahaa, Abbassy, Ahmed Amr, Abd El Ghany, Waleed, Abd Elkhalek, Amira, Abd ElMajeed, Emad, Abdalgaber, Mohammad, AbdAllah, Mohamed, Abdallah, Marwa, Abdallah, Nourhan, Abdelaleem, Shereen, Abdelghani, Yasser, Abdelghany, Wael, Abdelhalim, Safaa Mohamed, Abdelhamid, Wafaa, Abdelhamid, Nehal, Abdelkader, Nadia A., Abdelkreem, Elsayed, Abdelmohsen, Aly Mohamed, Abdelrahman, Awny Ali, Abd-elsalam, Sherief M, Abdeltawab, Doaa, Abduh, Abdulbaset, Abdulhakam, Nada, Abdulla, Maheeba, Abedpoor, Navid, Abenavoli, Ludovico, Åberg, Fredrik, Ablack, Omala, Abo elftouh, Mostafa, Abo-Amer, Yousry Esam-Eldin, Aboubkr, Ashraf, Aboud, Alaa, Abouelnaga, Amr M., Aboufarrag, Galal A., Aboutaleb, Ashraf, Abundis, Leticia, Adalı, Gupse, Adames, Enrique, Adams, Leon, Adda, Danjuma, Adel, Noor, Adel, Nada, Adel Sayed, Muhammad, Afaa, Taiba Jibril, Afredj, Nawal, Aghayeva, Gulnara, Aghemo, Alessio, Aguilar-Salinas, Carlos A., Ahlenstiel, Golo, Ahmady, Walid, Ahmed, Wafaa, Ahmed, Amira, Ahmed, Samah Nasser, Ahmed, Heba Mostafa, Ahmed, Rasha, Aigner, Elmar, Akarsu, Mesut, Akroush, Maisam, Akyuz, Umit, Al Mahtab, Mamun, Al Qadiri, Tahani, Al Rawahi, Yusriya, AL rubaee, Razzaq, Al Saffar, Muna, Alam, Shahinul, Al-Ani, Zaid, Albillos, Agustín, Alboraie, Mohamed, Al-Busafi, Said, Al-Emam, Mohamed, Alharthi, Jawaher, Ali, Kareem, Ali, Basma Abdelmoez, Ali, Mohammad, Ali, Raja Affendi Raja, Alisi, Anna, AL-Khafaji, Ali Raad, Alkhatry, Maryam, Aller, Rocio, Almansoury, Yahya, Al-Naamani, Khalid, Alnakeeb, Alaa, Alonso, Anna, Alqahtani, Saleh A., Alrabadi, Leina, Alswat, Khalid, Altaher, Mahir, Altamimi, Turki, Altamirano, Jose, Alvares-da-Silva, Mario R., Aly, Elsragy Adel M., Alzahaby, Amgad, Alzamzamy, Ahmed, Amano, Keisuke, Amer, Maysa A., Amin, Mona A., Amin, Sayed A., Amir, Ashraf A., Ampuero, Javier, Anas, Noha, Andreone, Pietro, Andriamandimby, Soa Fy, Anees, Mahmoud, Angela, Peltec, Antonios, Manal, Arafat, Wael, Araya, Jose Moreno, Armendariz-Borunda, Juan, Armstrong, Matthew J., Ashktorab, Hassan, Aspichueta, Patricia, Assal, Fathia, Atef, Mira, Attia, Dina, Atwa, Hoda, Awad, Reham, Awad, Mohyeldeen Abd Elaziz, Awny, Sally, Awolowo, Obafemi, Awuku, Yaw Asante, Ayada, Ibrahim, Aye, Than Than, Ayman, Sherif, Ayman, Hedy, Ayoub, Hesham, Azmy, Hosny M., Babaran, Romiro P., Badreldin, Omneya, Badry, Ahmed, Bahçecioğlu, İbrahim Halil, Bahour, Amira, Bai, Jiajia, Balaban, Yasemin, Balasubramanyam, Muthuswamy, Bamakhrama, Khaled, Banales, Jesus M, Bangaru, Babu, Bao, Jianfeng, Barahona, Jorge Suazo, Barakat, Salma, Barbalho, Sandra Maria, Barbra, Bikwa, Barranco, Beatriz, Barrera, Francisco, Baumann, Ulrich, Bazeed, Shamardan, Bech, Eva, Benayad, Aourarh, Benesic, Andreas, Bernstein, David, Bessone, Fernando, Birney, Susie, Bisseye, Cyrille, Blake, Martin, Bobat, Bilal, Bonfrate, Leonilde, Bordin, Dmitry S, Bosques-Padilla, Francisco, Boursier, Jerome, Boushab, Boushab Mohamed, Bowen, David, Bravo, Patricia Medina, Brennan, Paul N, Bright, Bisi, Broekaert, Ilse, Buque, Xabier, Burgos-Santamaría, Diego, Burman, Julio, Busetto, Luca, Byrne, Chris D., Cabral-Prodigalidad, Patricia Anne I., Cabrera-Alvarez, Guillermo, Cai, Wei, Cainelli, Francesca, Caliskan, Ali Riza, Canbay, Ali, Cano-Contreras, Ana, Cao, Hai-Xia, Cao, Zhujun, Carrion, Andres, Carubbi, Francesca, Casanovas, Teresa, Castellanos Fernández, Marlen Ivón, Chai, Jin, Chan, Siew Pheng, Charatcharoenwitthaya, Phunchai, Chavez-Tapia, Norberto, Chayama, Kazuaki, Chen, Jinjun, Chen, Lin, Chen, Zhong-Wei, Chen, Huiting, Chen, Sui-Dan, Chen, Qiang, Chen, Yaxi, Chen, Gang, Chen, En-Quang, Chen, Fei, Chen, Pei-Jer, Cheng, Robert, Cheng, Wendy, Chieh, Jack Tan Wei, Chokr, Imad, Cholongitas, Evangelos, Choudhury, Ashok, Chowdhury, Abhijit, Chukwudike, Evaristus Sunday, Ciardullo, Stefano, Clayton, Michelle, Clement, Karine, Cloa, Marie Michelle, Coccia, Cecilia, Collazos, Cristina, Colombo, Massimo, Cosar, Arif Mansur, Cotrim, Helma Pinchemel, Couillerot, Joris, Coulibaly, Alioune, Crespo, Gonzalo, Crespo, Javier, Cruells, Maria, Cua, Ian Homer Y., Dabbous, Hesham K., Dalekos, George N, D'Alia, Patricia, Dan, Li, Dao, Viet Hang, Darwish, Mostafa, Datz, Christian, Davalos-Moscol, Milagros B, Dawoud, Heba, de Careaga, Blanca Olaechea, de Knegt, Robert, de Ledinghen, Victor, de Silva, Janaka, Debzi, Nabil, Decraecker, Marie, Del Pozo, Elvira, Delgado, Teresa C, Delgado-Blanco, Manuel, Dembiński, Łukasz, Depina, Adilson, Derbala, Moutaz, Desalegn, Hailemichael, Desbois-Mouthon, Christèle, Desoky, Mahmoud, Dev, Anouk, Di Ciaula, Agostino, Diago, Moisés, Diallo, Ibrahima, Díaz, Luis Antonio, Dirchwolf, Melisa, Dongiovanni, Paola, Dorofeyev, Andrriy, Dou, Xiaoguang, Douglas, Mark W., Doulberis, Michael, Dovia, Cecil K., Doyle, Adam, Dragojević, Ivana, Drenth, Joost PH, Duan, Xuefei, Dulskas, Audrius, Dumitrascu, Dan L, Duncan, Oliver, Dusabejambo, Vincent, Dwawhi, Rev. Shem N.A., Eiketsu, Sho, El Amrousy, Doaa, El Deeb, Ahmed, El Deriny, Ghada, El Din, Hesham Salah, El Kamshishy, Salwa, El Kassas, Mohamed, El Raziky, Maissa, Elagamy, Osama A, Elakel, Wafaa, Elalfy, Dina, Elaraby, Hanaa, ElAwady, Heba, Elbadawy, Reda, Eldash, Hanaa Hassan, Eldefrawy, Manal S., Elecharri, Carol Lezama, Elfaramawy, Amel, Elfatih, Mohammed, Elfiky, Mahmoud, Elgamsy, Mohamed, Elgendy, Mohamed, El-Guindi, Mohamed A., Elhussieny, Nagi, Eliwa, Ahmed Maher, Elkabbany, Zeineb, El-Khayat, Hesham, El-Koofy, Nehal M., Elmetwalli, Alaa, Elrabat, Amr, El-Raey, Fathiya, Elrashdy, Fatma, Elsahhar, Medhat, Elsaid, Esraa M., Elsayed, Shimaa, Elsayed, Hany, Elsayed, Aly, Elsayed, Amr M., Elsayed, Hamdy, El-Serafy, Magdy, Elsharkawy, Ahmed M., Elsheemy, Reem Yehia, Elshemy, Eman Elsayed, Elsherbini, Sara, Eltoukhy, Naglaa, Elwakil, Reda, Emad, Ola, Emad, Shaimaa, Embabi, Mohamed, Ergenç, Ilkay, Ermolova, Tatiana, Esmat, Gamal, Esmat, Doaa M., Estupiñan, Enrique Carrera, Ettair, Said, Eugen, Tcaciuc, Ezz-Eldin, Mohammed, Falcón, Lidia Patricia Valdivieso, Fan, Yu-Chen, Fandari, Samah, Farag, Mahmoud, Farahat, Taghreed Mohamed, Fares, Eman M., Fares, Michael, Fassio, Eduardo, Fathy, Hayam, Fathy, Dina, Fathy, Wael, Fayed, Soheir, Feng, Dan, Feng, Gong, Fernández-Bermejo, Miguel, Ferreira, Cristina Targa, Ferrer, Javier Díaz, Forbes, Alastair, Fouad, Rabab, Fouad, Hanan M., Frisch, Tove, Fujii, Hideki, Fukunaga, Shuhei, Fukunishi, Shinya, Fulya, Hacer, Furuhashi, Masato, Gaber, Yasmine, Galang, Augusto Jose G., Gallardo, Jacqueline Cordova, Galloso, Rocío, Gamal, Mahmoud, Gamal, Reham, Gamal, Hadeel, Gan, Jian, Ganbold, Anar, Gao, Xin, Garas, George, Garba, Tony, García-Cortes, Miren, García-Monzón, Carmelo, García-Samaniego, Javier, Gastaldelli, Amalia, Gatica, Manuel, Gatley, Elizabeth, Gegeshidze, Tamar, Geng, Bin, Ghazinyan, Hasmik, Ghoneem, Salma, Giacomelli, Luca, Giannelli, Gianluigi, Giannini, Edoardo G., Giefer, Matthew, Ginès, Pere, Girala, Marcos, Giraudi, Pablo J, Goh, George Boon-Bee, Gomaa, Ahmed Ali, Gong, Benbingdi, Gonzales, Dina Hilda C., Gonzalez, Humberto C., Gonzalez-Huezo, Maria Saraí, Graupera, Isabel, Grgurevic, Ivica, Grønbæk, Henning, Gu, Xuelian, Guan, Lin, Gueye, Ibrahima, Guingané, Alice Nanelin, Gul, Ozen Oz, Gul, Cuma Bulent, Guo, Qing, Gupta, Pramendra Prasad, Gurakar, Ahmet, Gutierrez, Juan Carlos Restrepo, Habib, Ghada, Hafez, Azaa, Hagman, Emilia, Halawa, Eman, Hamdy, Osama, Hamed, Abd Elkhalek, Hamed, Dina H., Hamid, Saeed, Hamoudi, Waseem, Han, Yu, Haridy, James, Haridy, Hanan, Harris, David C H Harris, Hart, Michael, Hasan, Fuad, Hashim, Almoutaz, Hassan, Israa, Hassan, Ayman, Hassan, Essam Ali, Hassan, Adel Ahmed, Hassan, Magda Shehata, Hassanin, Fetouh, Hassnine, Alshymaa, Haukeland, John Willy, Hawal, Amr Ismael M., He, Jinfan, He, Qiong, He, Yong, He, Fang-Ping, Hegazy, Mona, Hegazy, Adham, Henegil, Osama, Hernández, Nelia, Hernández-Guerra, Manuel, Higuera-de-la-Tijera, Fatima, Hindy, Ibrahim, Hirota, Keisuke, Ho, Lee Chi, Hodge, Alexander, Hosny, Mohamed, Hou, Xin, Huang, Jiao-Feng, Huang, Yan, Huang, Zhifeng, Huang, Yuan, Huang, Ang, Huang, Xiao-Ping, Hui-ping, Sheng, Hunyady, Bela, Hussein, Mennatallah A., Hussein, Osama, Hussien, Shahinaz Mahmoud, Ibáñez-Samaniego, Luis, Ibdah, Jamal, Ibrahim, Luqman, Ibrahim, Miada, Ibrahim, Ibrahim, Icaza-Chávez, Maria E., Idelbi, Sahar, Idilman, Ramazan Idilman, Ikeda, Mayumi, Indolfi, Giuseppe, Invernizzi, Federica, Irshad, Iram, Isa, Hasan Mohamed Ali, Iskandar, Natacha Jreige, Ismaiel, Abdulrahman, Ismail, Mariam, Ismail, Zulkifli, Ismail, Faisal, Iwamoto, Hideki, Jack, Kathryn, Jacob, Rachael, Jafarov, Fuad, Jafri, Wasim, Jahshan, Helen, Jalal, Prasun K, Jancoriene, Ligita, Janicko, Martin, Jayasena, Hiruni, Jefferies, Meryem, Jha, Vivekanand, Ji, Fanpu, Ji, Yaqiu, Jia, Jidong, Jiang, Changtao, Jiang, Ni, Jiang, Zong-zhe, Jin, Xing, Jin, Yi, Jing, Xu, Jingyu, Qian, Jinjolava, Maia, Jong, FX Himawan Haryanto, Jucov, Alina, Julius, Ibecheole, Kaddah, Mona, Kamada, Yoshihiro, kamal, Abobakr, Kamal, Enas Mohamed, Kamel, Ashraf Sayed, Kao, Jia-Horng, Karin, Maja, Karlas, Thomas, Kashwaa, Mohammad, Katsidzira, Leolin, Kaya, Eda, Kayasseh, M.Azzam, Keenan, Bernadette, Keklikkiran, Caglayan, Keml, William, Khalaf, Deia K., Khalefa, Rofida, Khamis, Sherin, Khater, Doaa, khattab, Hamed, Khavkin, Anatoly, Khlynova, Olga, Khmis, Nabil, Kobyliak, Nazarii, Koffas, Apostolos, Koike, Kazuhiko, Kok, Kenneth Y.Y., Koller, Tomas, Komas, Narcisse Patrice, Korochanskaya, Nataliya V., Koulla, Yannoula, Koya, Shunji, Kraft, Colleen, Kraja, Bledar, Krawczyk, Marcin, Kuchay, Mohammad Shafi, Kulkarni, Anand V, Kumar, Ashish, Kumar, Manoj, Lakoh, Sulaiman, Lam, Philip, Lan, Ling, Lange, Naomi F., Lankarani, Kamran Bagheri, Lanthier, Nicolas, Lapshyna, Kateryna, Lashen, Sameh A., Laure, Konang Nguieguia Justine, Lazebnik, Leonid, Lebrec, Didier, Lee, Samuel S., Lee, Way Seah, Lee, Yeong Yeh, Leeming, Diana Julie, Leite, Nathalie Carvalho, Leon, Roberto, Lesmana, Cosmas Rinaldi Adithya, Li, Junfeng, Li, Qiong, Li, Jun, Li, Yang-Yang, Li, Yufang, Li, Lei, Li, Min, li, Yiling, Liang, Huiqing, Lijuan, Tang, Lim, Seng Gee, Lim, Lee-Ling, Lin, Shumei, Lin, Han-Chieh, Lin, Rita, Lithy, Rania, Liu, Yaru, Liu, Yuanyuan, Liu, Xin, Liu, Wen-Yue, Liu, Shourong, Liu, Ken, Liu, Tian, Lonardo, Amedeo, López, Mariana Bravo, López-Benages, Eva, Lopez-Jaramillo, Patricio, Lu, Huimin, Lu, Lun Gen, Lu, Yan, Lubel, John, Lui, Rashid, Lupasco, Iulianna, Luzina, Elena, Lv, Xiao-Hui, Lynch, Kate, Ma, Hong-Lei, Machado, Mariana Verdelho, Maduka, Nonso, Madzharova, Katerina, Magdaong, Russellini, Mahadeva, Sanjiv, Mahfouz, Amel, Mahmood, Nik Ritza Kosai Nik, Mahmoud, Eman, Mahrous, Mohamed, Maiwall, Rakhi, Majeed, Ammar, Majumdar, Avik, Mak, Loey, Maklouf, Madiha M, Malekzadeh, Reza, Mandato, Claudia, Mangia, Alessandra, Mann, Jake, Mansour, Hala Hussien, Mansouri, Abdellah, Mantovani, Alessandro, Mao, Jun qian, Maramag, Flor, Marchesini, Giulio, Marcus, Claude, Marinho, Rui António Rocha Tato, Martinez-Chantar, Maria L, Martins, Antonieta A. Soares, Marwan, Rana, Mason, Karen Frances, Masoud, Ghadeer, Massoud, Mohamed Naguib, Matamoros, Maria Amalia, Mateos, Rosa Martín, Mawed, Asmaa, Mbanya, Jean Claude, Mbendi, Charles, McColaugh, Lone, McLeod, Duncan, Medina, Juan Francisco Rivera, Megahed, Ahmed, Mehrez, Mai, Memon, Iqbal, Merat, Shahin, Mercado, Randy, Mesbah, Ahmed, Meskini, Taoufik, Metwally, Mayada, Metwaly, Rasha, Miao, Lei, Micah, Eileen, Miele, Luca, Milivojevic, Vladimir, Milovanovic, Tamara, Mina, Yvonne L., Mishkovik, Milan, Mishriki, Amal, Mitchell, Tim, Mohamed, Alshaimaa, Mohamed, Mona, Mohamed, Sofain, Mohammed, Shady, Mohammed, Ahmed, Mohan, Viswanathan, Mohie, Sara, Mokhtar, Aalaa, Moniem, Reham, Montilla, Mabel Segura, Morales, Jose Antonio Orozco, Morata, María María Sánchez, Moreno-Planas, Jose Maria, Morise, Silvia, Mosaad, Sherif, Moselhy, Mohamed, Mostafa, Alaa Mohamed, Mostafa, Ebraheem, Mouane, Nezha, Mousa, Nasser, Moustafa, Hamdy Mahfouz, Msherif, Abeer, Muller, Kate, Munoz, Christopher, Muñoz-Urribarri, Ana Beatriz, Murillo, Omar Alfaro, Mustapha, Feisul Idzwan, Muzurović, Emir, Nabil, Yehia, Nafady, Shaymaa, Nagamatsu, Ayu, Nakajima, Atsushi, Nakano, Dan, Nan, Yuemin, Nascimbeni, Fabio, Naseef, Mirella S., Nashat, Nagwa, Natalia, Taran, Negro, Francesco, Nersesov, Alexander V., Neuman, Manuela, Ng'wanasayi, Masolwa, Ni, Yan, Nicoll, Amanda, Niizeki, Takashi, Nikolova, Dafina, Ningning, Wang, Niriella, Madunil, Nogoibaeva, K.A, Nordien, Rozeena, O Sullivan, Catherine, O'Beirne, James, Obekpa, Solomon, Ocama, Ponsiano, Ochwoto, Missiani, Ogolodom, Michael Promise, Ojo, Olusegun, Okrostsvaridze, Nana, Oliveira, Claudia P., Omaña, Raul Contreras, Omar, Omneya M., Omar, Hanaa, Omar, Mabroka, Omran, Salma, Omran, Reham, Osman, Marian Muse, Owise, Nevin, Owusu-Ansah, Theobald, Padilla- Machaca, P. Martín, Palle, Sirish, Pan, Ziyan, Pan, Xiao-Yan, Pan, Qiuwei, Papaefthymiou, Apostolis, Paquissi, Feliciano Chanana, Par, Gabriella, Parkash, Arit, Payawal, Diana, Peltekian, Kevork M., Peng, Xuebin, Peng, Liang, Peng, Ying, Pengoria, Rahul, Perez, Martina, Pérez, José Luis, Pérez, Norma Marlene, Persico, Marcello, Pessoa, Mário Guimarães, Petta, Salvatore, Philip, Mathew, Plaz Torres, Maria Corina, Polavarapu, Naveen, Poniachik, Jaime, Portincasa, Piero, Pu, Chunwen, Pürnak, Tuğrul, Purwanto, Edhie, Qi, Xiaolong, Qi, Xingshun, Qian, Zibing, Qiang, Zhao, Qiao, Zengpei, Qiao, Liang, Queiroz, Alberto, Rabiee, Atoosa, Radwan, Manal, Rahetilahy, Alain Marcel, Ramadan, Yasmin, Ramadan, Dina, Ramli, Anis Safura, Ramm, Grant A., Ran, Ao, Rankovic, Ivan, RAO, Huiying, Raouf, Sara, Ray, Sayantan, Reau, Nancy, Refaat, Ahmed, Reiberger, Thomas, Remes-Troche, Jose M, Reyes, Eira Cerda, Richardson, Ben, Ridruejo, Ezequiel, Riestra Jimenez, Sergio, Rizk, Ibrahim, Roberts, Stuart, Roblero, Juan Pablo, Robles, Jorge Alberto Prado, Rockey, Don, Rodríguez, Manuel, Rodríguez Hernández, Heriberto, Román, Eva, Romeiro, Fernando Gomes, Romeo, Stefano, Rosales-Zabal, Jose Miguel, Roshdi, Georgina R., Rosso, Natalia, Ruf, Andres, Ruiz, Patricia Cordero, Runes, Nelia R., Ruzzenente, Andrea, Ryan, Marno, Saad, Ahmed, Sabbagh, Eman BE, Sabbah, Meriam, Saber, Shimaa, Sabrey, Reham, Sabry, Ramy, Saeed, Maysaa Abdallah, Said, Dina, Said, Ebada M, Sakr, Mohammad Amin, Salah, Yara, Salama, Rabab Maamoun, Salama, Asmaa, Saleh, Hussein, Saleh, Ahmed, Salem, Ahmed, Salem, Ahmed Thabet, Salifou, Alkassoum, Salih, Aso Faeq, Salman, Abdallah, Samouda, Hanen, Sanai, Faisal, Sánchez-Ávila, Juan Francisco, Sanker, Lakshumanan, Sano, Tomoya, Sanz, Miquel, Saparbu, Tobokalova, Sawhney, Rohit, Sayed, Fatma, Sayed, Sayed A., Sayed, Ashraf Othman, Sayed, Manar, Sebastiani, Giada, Secadas, Laura, Sediqi, Khawaja Qamaruddin, Seif, Sameh, Semida, Nady, Şenateş, Ebubekir, Serban, Elena Daniela, Serfaty, Lawrence, Seto, Wai-Kay, Sghaier, Ikram, Sha, Min, Shabaan, Hamada M., Shalaby, Lobna, Shaltout, Inass, Sharara, Ala I., Sharma, Vishal, Shawa, Isaac Thom, Shawkat, Ahmed, Shawky, Nehal, Shehata, Osama, Sheils, Sinead, Shewaye, Abate Bane, Shi, Guojun, Shi, Junping, Shimose, Shigeo, Shirono, Tomotake, Shou, Lan, Shrestha, Ananta, Shui, Guanghou, Sievert, William, Sigurdardottir, Solveig, Sira, Mostafa Mohamed, Siradj, Riyadh, Sison, Cecilia, Smyth, Linda, Soliman, Reham, Sollano, Jose D, Sombie, Roger, Sonderup, Mark, Sood, Siddharth, Soriano, German, Stedman, Catherine A M, Stefanyuk, Oksana, Štimac, Davor, Strasser, Simone, Strnad, Pavel, Stuart, Katherine, Su, Wen, Su, Minghua, Sumida, Yoshio, Sumie, Shuji, Sun, Dan-Qin, Sun, Jing, Suzuki, Hiroyuki, Svegliati-Baroni, Gianluca, Swar, Mohamed Osman, TAHARBOUCHT, S., Taher, Zenab, Takamura, Saori, Tan, Lin, Tan, Soek-Siam, Tanwandee, Tawesak, Tarek, Sara, Tatiana, Ghelimici, Tavaglione, Federica, Tecson, Gina Y., Tee, Hoi-Poh, Teschke, Rolf, Tharwat, Mostafa, Thong, Vo Duy, Thursz, Mark, Tine, Tulari, Tiribelli, Claudio, Tolmane, Ieva, Tong, Jing, Tongo, Marco, Torkie, Mamdouh, Torre, Aldo, Torres, Esther A, Trajkovska, Meri, Treeprasertsuk, Sombat, Tsutsumi, Tsubasa, Tu, Thomas, Tur, Josep A., Turan, Dilara, Turcan, Svetlana, Turkina, Svetlana, Tutar, Engin, Tzeuton, Christian, Ugiagbe, Rose, Uygun, Ahmet, Vacca, Michele, Vajro, Pietro, Van der Poorten, David, Van Kleef, Laurens A., Vashakidze, Eliza, Velazquez, Carlos Moctezuma, Velazquez, Mirtha Infante, Vento, Sandro, Verhoeven, Veronique, Vespasiani-Gentilucci, Umberto, Vethakkan, Shireene Ratna, Vilaseca, Josep, Vítek, Libor, Volkanovska, Ance, Wallace, Michael, Wan, Wang, Wang, Yan, Wang, Ying, Wang, Xiaolin, Wang, Xuemei, Wang, Chengyan, Wang, Chunjiong, Wang, Mingjie, Wangchuk, Pelden, Weltman, Martin, White, MaryFrances, Wiegand, Johannes, Wifi, Mohamed-Naguib, Wigg, Alan, Wilhelmi, Markus, William, Remon, Wittenburg, Henning, Wu, Shengjie, Wubeneh, Abdu Mohammed, Xia, Hongping, Xiao, Jian, Xiao, Xiao, Xiaofeng, Wang, Xiong, Wanyuan, Xu, Liang, Xu, Jie, Xu, Weiguo, Xu, Jing-Hang, Xu, Keshu, Xu, Yumin, Xu, Shi-Hao, Xu, Meng, Xu, Aimin, Xu, Chengfu, Yan, Hongmei, Yang, Jingyi, Yang, Rui-Xu, Yang, Yating, Yang, Qinhe, Yang, Naibin, Yao, Jia, Yara, Justine, Yaraş, Serkan, Yılmaz, Nimet, Younes, Ramy, younes, Huda, Young, Sona, Youssef, Farah, Yu, Yanyan, Yu, Ming-Lung, Yuan, Jing, Yue, Zhang, Yuen, Man-Fung, Yun, Wang, Yurukova, Nonka, Zakaria, Serag, Zaky, Samy, Zaldastanishvili, Maia, Zapata, Rodrigo, Zare, Nazanin, Zerem, Enver, Zeriban, Nema, Zeshuai, Xu, Zhang, Huijie, Zhang, Xuemei, Zhang, Yupei, Zhang, Wen-Hua, Zhang, Xuchen, Zhang, Yon-ping, Zhang, Yuexin, Zhang, Zhan-qing, Zhao, Jingmin, Zhao, Rong-Rong, Zhao, Hongwei, Zheng, Chao, Zheng, Yijie, Zheng, Ruidan, Zheng, Tian-Lei, Zheng, Kenneth, Zhou, Xi Qiao, Zhou, Yongjian, Zhou, Yu-Jie, Zhou, Hong, Zhou, Ling, Zhou, Yongning, Zhu, Long dong, Zhu, Yong Fen, Zhu, Yueyong, Zhu, Pei-Wu, Ziada, Ebtesam, Ziring, David, Ziyi, Li, Zou, Shanshan, Zou, Zhengsheng, Zou, Huaibin, Zuart Ruiz, Roberto, Méndez-Sánchez, Nahum, Bugianesi, Elisabetta, Gish, Robert G, Lammert, Frank, Tilg, Herbert, Nguyen, Mindie H, Sarin, Shiv K, Fabrellas, Núria, Zelber-Sagi, Shira, Fan, Jian-Gao, Shiha, Gamal, Targher, Giovanni, Zheng, Ming-Hua, Chan, Wah-Kheong, Vinker, Shlomo, Kawaguchi, Takumi, Castera, Laurent, Yilmaz, Yusuf, Korenjak, Marko, Spearman, C Wendy, Ungan, Mehmet, Palmer, Melissa, El-Shabrawi, Mortada, Gruss, Hans-Juergen, Dufour, Jean-François, Dhawan, Anil, Wedemeyer, Heiner, George, Jacob, Valenti, Luca, Fouad, Yasser, Romero‐Gomez, Manuel, and Eslam, Mohammed

Published
2022
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26. Baseline quantitative hepatitis B core antibody titre alone strongly predicts HBeAg seroconversion across chronic hepatitis B patients treated with peginterferon or nucleos(t)ide analogues

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Fan, Rong, Sun, Jian, Yuan, Quan, Xie, Qing, Bai, Xuefan, Ning, Qin, Cheng, Jun, Yu, Yanyan, Niu, Junqi, Shi, Guangfeng, Wang, Hao, Tan, Deming, Wan, Mobin, Chen, Shijun, Xu, Min, Chen, Xinyue, Tang, Hong, Sheng, Jifang, Lu, Fengmin, Jia, Jidong, Zhuang, Hui, Xia, Ningshao, Hou, Jinlin, Dou, Xiaoguang, Shi, Junping, Ren, Hong, Wang, Maorong, Ma, Hong, Gao, Zhiliang, Zhang, Hongfei, and Chen, Chengwei

Published
2016
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28. The Chinese Society of Hepatology position statement on the redefinition of fatty liver disease

Author

Nan, Yuemin, primary, An, Jihong, additional, Bao, Jianfeng, additional, Chen, Hongsong, additional, Chen, Yu, additional, Ding, Huiguo, additional, Dou, Xiaoguang, additional, Duan, Zhongping, additional, Fan, Jiangao, additional, Gao, Yanhang, additional, Han, Tao, additional, Han, Ying, additional, Hu, Peng, additional, Huang, Yan, additional, Huang, Yuan, additional, Jia, Jidong, additional, Jiang, Jiaji, additional, Jiang, Ying’an, additional, Li, Jie, additional, Li, Jun, additional, Li, Rongkuan, additional, Li, Shuchen, additional, Li, Wengang, additional, Li, Yufang, additional, Lin, Shumei, additional, Liu, Jingfeng, additional, Liu, Shourong, additional, Lu, Lungen, additional, Lu, Qinghua, additional, Luo, Xinhua, additional, Ma, Xiong, additional, Rao, Huiying, additional, Ren, Hong, additional, Ren, Wanhua, additional, Shang, Jia, additional, Shi, Li, additional, Su, Minghua, additional, Wang, Bingyuan, additional, Wang, Rongqi, additional, Wei, Lai, additional, Wen, Zhili, additional, Wu, Biao, additional, Wu, Jing, additional, Xin, Shaojie, additional, Xing, Huichun, additional, Xu, Jinghang, additional, Yan, Ming, additional, Yang, Jiming, additional, Yang, Jinhui, additional, Yang, Li, additional, Yang, Yongfeng, additional, Yu, Yanyan, additional, Zhang, Liaoyun, additional, Zhang, Lingyi, additional, Zhang, Xinxin, additional, Zhang, Yuguo, additional, Zhang, Yuexin, additional, Zhao, Jingmin, additional, Zhao, Shousong, additional, Zheng, Huanwei, additional, Zhou, Yongjian, additional, Zhou, Yongning, additional, Zhuang, Hui, additional, Zuo, Weize, additional, Xu, Xiaoyuan, additional, and Qiao, Liang, additional

Published
2021
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29. Randomized, three-arm study to optimize lamivudine efficacy in hepatitis B e antigen-positive chronic hepatitis B patients

Author

Liang, Xieer, Cheng, Jun, Sun, Yongtao, Chen, Xinyue, Li, Tong, Wang, Hao, Jiang, Jianning, Chen, Xiaoping, Long, Hui, Tang, Hong, Yu, Yanyan, Sheng, Jifang, Chen, Shijun, Niu, Junqi, Ren, Hong, Shi, Junping, Dou, Xiaoguang, Wan, Mobin, Jiang, Jiaji, Xie, Qing, Shi, Guangfeng, Ning, Qin, Chen, Chengwei, Tan, Deming, Ma, Hong, Sun, Jian, Jia, Jidong, Zhuang, Hui, and Hou, Jinlin

Published
2015
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33. The 104-week efficacy and safety of telbivudine-based optimization strategy in chronic hepatitis B patients: A randomized, controlled study

Author

Sun, Jian, Xie, Qing, Tan, Deming, Ning, Qin, Niu, Junqi, Bai, Xuefan, Fan, Rong, Chen, Shijun, Cheng, Jun, Yu, Yanyan, Wang, Hao, Xu, Min, Shi, Guangfeng, Wan, Mobin, Chen, Xinyue, Tang, Hong, Sheng, Jifang, Dou, Xiaoguang, Shi, Junping, Ren, Hong, Wang, Maorong, Zhang, Hongfei, Gao, Zhiliang, Chen, Chengwei, Ma, Hong, Jia, Jidong, and Hou, Jinlin

Published
2014
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34. Distribution and clinical correlates of viral and host genotypes in Chinese patients with chronic hepatitis C virus infection

Author

Rao, Huiying, Wei, Lai, Lopez-Talavera, Juan Carlos, Shang, Jia, Chen, Hong, Li, Jun, Xie, Qing, Gao, Zhiliang, Wang, Lei, Wei, Jia, Jiang, Jianning, Sun, Yongtao, Yang, Ruifeng, Li, Hong, Zhang, Haiying, Gong, Zuojiong, Zhang, Lunli, Zhao, Longfeng, Dou, Xiaoguang, Niu, Junqi, You, Hong, Chen, Zhi, Ning, Qin, Gong, Guozhong, Wu, Shuhuan, Ji, Wei, Mao, Qing, Tang, Hong, Li, Shuchen, Wei, Shaofeng, Sun, Jian, Jiang, Jiaji, Lu, Lungen, Jia, Jidong, and Zhuang, Hui

Published
2014
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36. SAT-193 - Efficacy and prediction analysis of pegylated interferon alpha-2b in treatment-naive HBeAg negative chronic hepatitis B patients with normal ALT: a multicenter real-world study (Ice-breakting Project in China)-Interim analysis

Author

Zhang, Chong, Zeng, Da-Wu, Cai, Da-Chuan, Xue, Xiu-Lan, Zhang, Ling-Yi, Song, Bao-Jun, Gao, Yu-Feng, Huang, Yan, Shang, Jia, Wu, Xiao-Feng, Zhang, Ying, Jin, Hua, Chen, Hui, Tang, Hong, Lu, Xiaobo, Guan, Yujuan, Min, Feng, Xu, Liang, Li, Gang, Wang, Zhen-Guang, and Dou, Xiaoguang

Published
2023
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37. Clinical significance of serum HBV RNA measurement in chronic hepatitis B patients

Author

LU Fengmin, DOU Xiaoguang, and ZHANG Wenhong

Subjects
chronic, RNA, lcsh:Diseases of the digestive system. Gastroenterology, hepatitis B, DNA, lcsh:RC799-869, hepatitis B virus, circular, nucleotides, nucleosides
Abstract

In the era of antiviral therapy with potent nucleos(t)ide analogues (NAs), serum HBV DNA is reduced to a level below the lower limit of detection in most chronic hepatitis B (CHB) patients, but the loss of serum HBV DNA only indicates that reverse transcription of virus is effectively inhibited and cannot truly reflect the transcriptional activity of covalently closed circular DNA (cccDNA) in hepatocytes. In addition, some patients, although with almost depleted or residual, silent cccDNA in liver tissue, were still positive for serum HBsAg after long-term treatment due to the integration of HBV DNA fragments. How to truly evaluate the presence and transcriptional activity of cccDNA in hepatocytes is still a problem that needs to be solved urgently. Serum HBV RNA comes from cccDNA transcript in liver tissue and is released into blood circulation as virus-like HBV RNA particles, since it is not effectively transformed to rcDNA. Therefore, in patients receiving the treatment with NAs, serum HBV RNA can qualitatively reflect the transcriptional activity of cccDNA in liver tissue. At present, most scholars think it is hard to achieve "complete cure" of CHB with current therapies. Therefore, we put forward a ladder-like improvement pattern from "partial cure" to "para-functional cure" and "clinical cure" (or "functional cure"). "Partial cure" based on the elimination or silence of cccDNA and persistently negative HBV RNA should be used to predict the risk of recurrence or virological rebound after drug withdrawal, and a low serum level of HBsAg combined with these two criteria should be used as the criteria for "quasi-clinical cure". The clinical significance of serum HBV RNA measurement needs to be addressed in multi-cohort clinical trails and/or improved in the real world studies.

Published
2018

38. Antiviral therapeutic strategies for chronic hepatitis B patients with a normal alanine aminotransferase level

Author

DING Yang and DOU Xiaoguang

Subjects
chronic, clinical protocols, lcsh:Diseases of the digestive system. Gastroenterology, hepatitis B, alanine transaminase, lcsh:RC799-869, digestive system diseases
Abstract

Alanine aminotransferase (ALT) is one of the most sensitive biochemical parameters used to reflect the degree of liver injury. It is generally believed that patients with hepatitis B virus (HBV) infection and a normal ALT level are in the immune tolerance state, and no antiviral therapy is required in patients without liver inflammation or those with mild liver inflammation. However, these patients are not always in the immune tolerance state, and the disease can insidiously progress to chronic hepatitis B (CHB), liver cirrhosis, and even hepatocellular carcinoma. Therefore, antiviral therapy for CHB patients with normal ALT has always been a hot topic of clinical research. This article elaborates on the association between ALT and liver inflammation in CHB patients and the timing of antiviral therapy for CHB patients with normal ALT.

Published
2018

40. aMAP risk score predicts hepatocellular carcinoma development in patients with chronic hepatitis

Author

Fan, Rong, primary, Papatheodoridis, George, additional, Sun, Jian, additional, Innes, Hamish, additional, Toyoda, Hidenori, additional, Xie, Qing, additional, Mo, Shuyuan, additional, Sypsa, Vana, additional, Guha, Indra Neil, additional, Kumada, Takashi, additional, Niu, Junqi, additional, Dalekos, George, additional, Yasuda, Satoshi, additional, Barnes, Eleanor, additional, Lian, Jianqi, additional, Suri, Vithika, additional, Idilman, Ramazan, additional, Barclay, Stephen T., additional, Dou, Xiaoguang, additional, Berg, Thomas, additional, Hayes, Peter C., additional, Flaherty, John F., additional, Zhou, Yuanping, additional, Zhang, Zhengang, additional, Buti, Maria, additional, Hutchinson, Sharon J., additional, Guo, Yabing, additional, Calleja, Jose Luis, additional, Lin, Lanjia, additional, Zhao, Longfeng, additional, Chen, Yongpeng, additional, Janssen, Harry L.A., additional, Zhu, Chaonan, additional, Shi, Lei, additional, Tang, Xiaoping, additional, Gaggar, Anuj, additional, Wei, Lai, additional, Jia, Jidong, additional, Irving, William L., additional, Johnson, Philip J., additional, Lampertico, Pietro, additional, and Hou, Jinlin, additional

Published
2020
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41. Relationship between Hepatitis B virus infection and platelet production and dysfunction.

Author

Jiang, Huinan, Li, Yanwei, Sheng, Qiuju, and Dou, Xiaoguang

Subjects
FIBROSIS, HEPATITIS B, BLOOD platelets, HEPATIC fibrosis, LIVER cells, HEPATITIS B virus
Abstract

Hepatitis B virus (HBV) is a kind of hepatotropic DNA virus. The main target organ is liver, except for liver, HBV has been found in a variety of extrahepatic tissues, such as kidney, thyroid, pancreas, bone marrow, etc. HBV can cause severe complications by invading these tissues. Among them, pancytopenia is one of the common complications, especially thrombocytopenia that causes life-threatening bleeding. However, the mechanism of thrombocytopenia is unclear and the treatment is extremely difficult. It has been confirmed that HBV has a close relationship with platelets. HBV can directly infect bone marrow, inhibit platelet production, and accelerate platelet destruction by activating monocyte-macrophage system and immune system. While platelets act as a double-edged sword to HBV. On one hand, the activated platelets can degranulate and release inflammatory mediators to help clear the viruses. Furthermore, platelets can provide anti-fibrotic molecules to improve liver functions and reduce hepatic fibrosis. On the other hand, platelets can also cause negative effects. The infected platelets collect HBV-specific CD8+ T cells and nonspecific inflammatory cells into liver parenchyma, inducing chronic inflammation, liver fibrosis and hepatic carcinoma. This article explores the interaction between HBV infection and platelets, providing a theoretical basis for clinical treatment of thrombocytopenia and severe hemorrhage caused by HBV infection. [ABSTRACT FROM AUTHOR]

Published
2022
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42. A systematic review of hepatitis C virus epidemiology in Asia, Australia and Egypt

Author

Sievert, William, Altraif, Ibrahim, Razavi, Homie A., Abdo, Ayman, Ahmed, Ezzat Ali, AlOmair, Ahmed, Amarapurkar, Deepak, Chen, Chien-Hung, Dou, Xiaoguang, El Khayat, Hisham, elShazly, Mohamed, Esmat, Gamal, Guan, Richard, Han, Kwang-Hyub, Koike, Kazuhiko, Largen, Angela, McCaughan, Geoff, Mogawer, Sherif, Monis, Ali, Nawaz, Arif, Piratvisuth, Teerha, Sanai, Faisal M., Sharara, Ala I., Sibbel, Scott, Sood, Ajit, Suh, Dong Jin, Wallace, Carolyn, Young, Kendra, and Negro, Francesco

Published
2011
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45. Combination of NA, PEG-IFN alpha-2b and GM-CSF enhanced hbsab production in NA experienced CHB patients (the anchor a study): an interim analysis

Author

Wu, Di, primary, Yan, Weiming, additional, Tan, Deming Tan, additional, Peng, Shifang, additional, Chen, Yongping, additional, Jiang, Jiaji, additional, Chen, Xin-Yue, additional, Dou, Xiaoguang, additional, Ma, Ke, additional, Wang, Peng, additional, Yin, Ping, additional, Sun, Li, additional, Han, Meifang, additional, and Ning, Qin, additional

Published
2020
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47. Association Between Negative Results From Tests for HBV DNA and RNA and Durability of Response After Discontinuation of Nucles(t)ide Analogue Therapy

Author

Fan, Rong, primary, Zhou, Bin, additional, Xu, Min, additional, Tan, Deming, additional, Niu, Junqi, additional, Wang, Hao, additional, Ren, Hong, additional, Chen, Xinyue, additional, Wang, Maorong, additional, Ning, Qin, additional, Shi, Guangfeng, additional, Sheng, Jifang, additional, Tang, Hong, additional, Bai, Xuefan, additional, Liu, Shi, additional, Lu, Fengmin, additional, Peng, Jie, additional, Sun, Jian, additional, Xie, Qing, additional, Hou, Jinlin, additional, Wan, Mobin, additional, Chen, Shijun, additional, Yu, Yanyan, additional, Ma, Hong, additional, Cheng, Jun, additional, Zhang, Hongfei, additional, Liu, Huimin, additional, Gao, Zhiliang, additional, and Dou, Xiaoguang, additional

Published
2020
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49. Baseline Characteristics and Treatment Patterns of the Patients Recruited to the China Registry of Hepatitis B

Author

Shan, Shan, primary, You, Hong, additional, Niu, Junqi, additional, Shang, Jia, additional, Xie, Wen, additional, Zhang, Yuexin, additional, Li, Xun, additional, Ren, Hong, additional, Tang, Hong, additional, Ding, Huiguo, additional, Wang, Xihong, additional, Nan, Yuemin, additional, Dou, Xiaoguang, additional, Han, Tao, additional, Zhang, Lingyi, additional, Liu, Xiaoqing, additional, Deng, Cunliang, additional, Cheng, Jilin, additional, Wang, Xiaozhong, additional, Xie, Qing, additional, Lin, Shumei, additional, Huang, Yan, additional, Xu, Youqing, additional, Xiong, Yong, additional, Li, Wu, additional, Yan, Xuebing, additional, Piao, Hongxin, additional, Huang, Wenxiang, additional, Lu, Qinghua, additional, Gong, Weijin, additional, Li, Shiping, additional, Hu, Xiaoxuan, additional, Zhang, Xiaolan, additional, Liu, Shourong, additional, Li, Yufang, additional, Yang, Dongliang, additional, Li, Hai, additional, Yang, Caixia, additional, Cheng, Mingliang, additional, Zhang, Liaoyun, additional, Zheng, Huanwei, additional, Luo, Xinhua, additional, Lin, Feng, additional, Wang, Lei, additional, Xu, Guanghua, additional, Xu, Xiaoyuan, additional, Wei, Lai, additional, Hou, Jinlin, additional, Duan, Zhongping, additional, Zhuang, Hui, additional, Yang, Xizhong, additional, Kong, Yuanyuan, additional, and Jia, Jidong, additional

Published
2019
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50. Association of central obesity with hepatocellular carcinoma in patients with chronic hepatitis B receiving antiviral therapy.

Author

Fan, Rong, Niu, Junqi, Ma, Hong, Xie, Qing, Cheng, Jun, Rao, Huiying, Dou, Xiaoguang, Xie, Jianping, Zhao, Wei, Peng, Jie, Gao, Zhiliang, Gao, Hongbo, Chen, Xinyue, Chen, Jinjun, Li, Qiang, Tang, Hong, Zhang, Zhengang, Ren, Hong, Cheng, Mingliang, and Liang, Xieer

Subjects
CHRONIC hepatitis B, OBESITY, HEPATOCELLULAR carcinoma, WAIST-hip ratio, METABOLIC disorders, PROPENSITY score matching
Abstract

Summary: Background: Obesity is typically associated with metabolic dysfunction, but its impact on hepatocellular carcinoma (HCC) remains unclear in patients with chronic hepatitis B (CHB). Aim: To study the effect of obesity on HCC development in patients with CHB receiving antiviral therapy. Methods: We included patients from a Chinese multicentre, prospective, observational, treated CHB cohort in this study. General obesity was evaluated by body‐mass index (BMI). Central obesity was evaluated by waist circumference, waist‐to‐hip ratio and waist‐to‐height ratio. Results: A total of 5754 nucleos(t)ide analogue treated patients were enrolled in the analysis. The 5‐year cumulative incidence of HCC was 2.9%. Waist‐to‐height ratio performed better in predicting HCC development than BMI, waist circumference or waist‐to‐hip ratio. Patients with central obesity (defined as waist‐to‐height ratio >0.5) had significantly higher 5‐year incidence of HCC than those without central obesity in the overall population (3.9% vs 2.1%, hazard ratio [HR]: 2.06, P = 0.0001) and 745 propensity score matched pairs (4.7% vs 2.3%, HR: 2.04, P = 0.026), respectively. Besides cirrhosis status and aMAP HCC risk score, central obesity was also independently associated with HCC risk (HR: 1.63, P = 0.013). Waist‐to‐height ratio gain within 1 year was associated with a significantly higher HCC risk with an adjusted HR value of 1.88 (95% confidence interval: 1.12‐3.13, P = 0.017). Conclusions: Central obesity, evaluated by the waist‐to‐height ratio, was associated with a twofold increase in HCC risk among CHB patients receiving antiviral treatment, highlighting the important role of abnormal metabolic function in the progression of liver disease. [ABSTRACT FROM AUTHOR]

Published
2021
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