311 results on '"Dou, Xinyu"'
Search Results
2. Prognostic value of dynamic changes of pre- and post-operative tumor markers in colorectal cancer
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Ren, Guangming, Zheng, Gaozan, Du, Kunli, Dang, Zhangfeng, Dan, Hanjun, Dou, Xinyu, Duan, Lili, Xie, Zhenyu, Niu, Liaoran, Tian, Ye, Zheng, Jianyong, and Feng, Fan
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- 2024
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3. Endothelial cell heterogeneity in colorectal cancer: tip cells drive angiogenesis
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Xie, Zhenyu, Niu, Liaoran, Du, Kunli, Chen, Ling, Zheng, Gaozan, Dai, Songchen, Dan, Hanjun, Duan, Lili, Dou, Xinyu, Feng, Fan, Zhang, Jian, and Zheng, Jianyong
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- 2024
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4. Transcriptome and single-cell analysis reveal disulfidptosis-related modification patterns of tumor microenvironment and prognosis in osteosarcoma
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Wang, Linbang, Liu, Yu, Tai, Jiaojiao, Dou, Xinyu, Yang, Hongjuan, Li, Qiaochu, Liu, Jingkun, Yan, Ziqiang, and Liu, Xiaoguang
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- 2024
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5. L-cysteine contributes to destructive activities of odontogenic cysts/tumor
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Li, Ji, Feng, Chunyu, Pang, Xiaochan, Li, Xiang, Dou, Xinyu, Jiang, Erhui, and Shang, Zhengjun
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- 2024
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6. Erratum to: A justice and innovative way ahead of consumption-based emission accounting approach
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Shen, Qun, Duan, Hongbo, Tang, Yun, Tang, Linbing, Shang, Li, Dou, Xinyu, Wei, Wei, Chen, Weiqiang, and Liu, Zhu
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- 2024
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7. Carbon Monitor Europe near-real-time daily CO2 emissions for 27 EU countries and the United Kingdom.
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Ke, Piyu, Deng, Zhu, Zhu, Biqing, Zheng, Bo, Wang, Yilong, Boucher, Olivier, Arous, Simon Ben, Zhou, Chuanlong, Andrew, Robbie M, Dou, Xinyu, Sun, Taochun, Song, Xuanren, Li, Zhao, Yan, Feifan, Cui, Duo, Hu, Yifan, Huo, Da, Chang, Jean-Pierre, Engelen, Richard, Davis, Steven J, Ciais, Philippe, and Liu, Zhu
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Climate Action - Abstract
With the urgent need to implement the EU countries pledges and to monitor the effectiveness of Green Deal plan, Monitoring Reporting and Verification tools are needed to track how emissions are changing for all the sectors. Current official inventories only provide annual estimates of national CO2 emissions with a lag of 1+ year which do not capture the variations of emissions due to recent shocks including COVID lockdowns and economic rebounds, war in Ukraine. Here we present a near-real-time country-level dataset of daily fossil fuel and cement emissions from January 2019 through December 2021 for 27 EU countries and UK, which called Carbon Monitor Europe. The data are calculated separately for six sectors: power, industry, ground transportation, domestic aviation, international aviation and residential. Daily CO2 emissions are estimated from a large set of activity data compiled from different sources. The goal of this dataset is to improve the timeliness and temporal resolution of emissions for European countries, to inform the public and decision makers about current emissions changes in Europe.
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- 2023
8. Carbon Monitor Europe, near-real-time daily CO$_2$ emissions for 27 EU countries and the United Kingdom
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Ke, Piyu, Deng, Zhu, Zhu, Biqing, Zheng, Bo, Wang, Yilong, Boucher, Olivier, Arous, Simon Ben, Zhou, Chuanlong, Dou, Xinyu, Sun, Taochun, Li, Zhao, Yan, Feifan, Cui, Duo, Hu, Yifan, Huo, Da, Pierre, Jean, Engelen, Richard, Davis, Steven J., Ciais, Philippe, and Liu, Zhu
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Physics - Geophysics ,Economics - General Economics ,Physics - Atmospheric and Oceanic Physics - Abstract
With the urgent need to implement the EU countries pledges and to monitor the effectiveness of Green Deal plan, Monitoring Reporting and Verification tools are needed to track how emissions are changing for all the sectors. Current official inventories only provide annual estimates of national CO$_2$ emissions with a lag of 1+ year which do not capture the variations of emissions due to recent shocks including COVID lockdowns and economic rebounds, war in Ukraine. Here we present a near-real-time country-level dataset of daily fossil fuel and cement emissions from January 2019 through December 2021 for 27 EU countries and UK, which called Carbon Monitor Europe. The data are calculated separately for six sectors: power, industry, ground transportation, domestic aviation, international aviation and residential. Daily CO$_2$ emissions are estimated from a large set of activity data compiled from different sources. The goal of this dataset is to improve the timeliness and temporal resolution of emissions for European countries, to inform the public and decision makers about current emissions changes in Europe.
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- 2022
9. Near-real-time global gridded daily CO$_2$ emissions 2021
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Dou, Xinyu, Hong, Jinpyo, Ciais, Philippe, Chevallier, Frédéric, Yan, Feifan, Yu, Ying, Hu, Yifan, Huo, Da, Sun, Yun, Wang, Yilong, Davis, Steven J., Crippa, Monica, Janssens-Maenhout, Greet, Guizzardi, Diego, Solazzo, Efisio, Lin, Xiaojuan, Song, Xuanren, Zhu, Biqing, Cui, Duo, Ke, Piyu, Wang, Hengqi, Zhou, Wenwen, Huang, Xia, Deng, Zhu, and Liu, Zhu
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Physics - Atmospheric and Oceanic Physics - Abstract
We present a near-real-time global gridded daily CO$_2$ emissions dataset (GRACED) throughout 2021. GRACED provides gridded CO$_2$ emissions at a 0.1degree*0.1degree spatial resolution and 1-day temporal resolution from cement production and fossil fuel combustion over seven sectors, including industry, power, residential consumption, ground transportation, international aviation, domestic aviation, and international shipping. GRACED is prepared from a near-real-time daily national CO$_2$ emissions estimates (Carbon Monitor), multi-source spatial activity data emissions and satellite NO$_2$ data for time variations of those spatial activity data. GRACED provides the most timely overview of emissions distribution changes, which enables more accurate and timely identification of when and where fossil CO$_2$ emissions have rebounded and decreased. Uncertainty analysis of GRACED gives a grid-level two-sigma uncertainty of value of 19.9% in 2021, indicating the reliability of GRACED was not sacrificed for the sake of higher spatiotemporal resolution that GRACED provides. Continuing to update GRACED in a timely manner could help policymakers monitor energy and climate policies' effectiveness and make adjustments quickly.
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- 2022
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10. Near-real-time global gridded daily CO2 emissions 2021
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Dou, Xinyu, Hong, Jinpyo, Ciais, Philippe, Chevallier, Frédéric, Yan, Feifan, Yu, Ying, Hu, Yifan, Huo, Da, Sun, Yun, Wang, Yilong, Davis, Steven J, Crippa, Monica, Janssens-Maenhout, Greet, Guizzardi, Diego, Solazzo, Efisio, Lin, Xiaojuan, Song, Xuanren, Zhu, Biqing, Cui, Duo, Ke, Piyu, Wang, Hengqi, Zhou, Wenwen, Huang, Xia, Deng, Zhu, and Liu, Zhu
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Earth Sciences ,Engineering ,Geoinformatics ,Climate Action - Abstract
We present a near-real-time global gridded daily CO2 emissions dataset (GRACED) throughout 2021. GRACED provides gridded CO2 emissions at a 0.1° × 0.1° spatial resolution and 1-day temporal resolution from cement production and fossil fuel combustion over seven sectors, including industry, power, residential consumption, ground transportation, international aviation, domestic aviation, and international shipping. GRACED is prepared from the near-real-time daily national CO2 emissions estimates (Carbon Monitor), multi-source spatial activity data emissions and satellite NO2 data for time variations of those spatial activity data. GRACED provides the most timely overview of emissions distribution changes, which enables more accurate and timely identification of when and where fossil CO2 emissions have rebounded and decreased. Uncertainty analysis of GRACED gives a grid-level two-sigma uncertainty of value of ±19.9% in 2021, indicating the reliability of GRACED was not sacrificed for the sake of higher spatiotemporal resolution that GRACED provides. Continuing to update GRACED in a timely manner could help policymakers monitor energy and climate policies' effectiveness and make adjustments quickly.
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- 2023
11. Near-real-time estimates of daily CO2 emissions from 1500 cities worldwide
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Huo, Da, Huang, Xiaoting, Dou, Xinyu, Ciais, Philippe, Li, Yun, Deng, Zhu, Wang, Yilong, Cui, Duo, Benkhelifa, Fouzi, Sun, Taochun, Zhu, Biqing, Roest, Geoffrey, Gurney, Kevin R., Ke, Piyu, Guo, Rui, Lu, Chenxi, Lin, Xiaojuan, Lovell, Arminel, Appleby, Kyra, DeCola, Philip L., Davis, Steven J., and Liu, Zhu
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Physics - Physics and Society ,Physics - Atmospheric and Oceanic Physics - Abstract
Building on near-real-time and spatially explicit estimates of daily carbon dioxide (CO2) emissions, here we present and analyze a new city-level dataset of fossil fuel and cement emissions. Carbon Monitor Cities provides daily, city-level estimates of emissions from January 2019 through December 2021 for 1500 cities in 46 countries, and disaggregates five sectors: power generation, residential (buildings), industry, ground transportation, and aviation. The goal of this dataset is to improve the timeliness and temporal resolution of city-level emission inventories and includes estimates for both functional urban areas and city administrative areas that are consistent with global and regional totals. Comparisons with other datasets (i.e. CEADs, MEIC, Vulcan, and CDP) were performed, and we estimate the overall uncertainty to be 21.7%. Carbon Monitor Cities is a near-real-time, city-level emission dataset that includes cities around the world, including the first estimates for many cities in low-income countries. A more complete description of this dataset is published in Scientific Data (https://doi.org/10.1038/s41597-022-01657-z).
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- 2022
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12. Influence of extreme 2022 heatwave on megacities' anthropogenic CO2 emissions in lower-middle reaches of the Yangtze River
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Tan, Jingye, Wang, Jun, Wang, Haikun, Liu, Zhu, Zeng, Ning, Yan, Ran, Dou, Xinyu, Wang, Xunmei, Wang, Meirong, Jiang, Fei, Wang, Hengmao, Ju, Weimin, and Chen, Jing M.
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- 2024
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13. A nomogram was developed using clinicopathological features to predict postoperative liver metastasis in patients with colorectal cancer
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Dou, Xinyu, Xi, Jiaona, Zheng, Gaozan, Ren, Guangming, Tian, Ye, Dan, Hanjun, Xie, Zhenyu, Niu, Liaoran, Duan, Lili, Li, Ruikai, Wu, Hongze, Feng, Fan, and Zheng, Jianyong
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- 2023
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14. Global Gridded Daily CO$_2$ Emissions
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Dou, Xinyu, Wang, Yilong, Ciais, Philippe, Chevallier, Frédéric, Davis, Steven J., Crippa, Monica, Janssens-Maenhout, Greet, Guizzardi, Diego, Solazzo, Efisio, Yan, Feifan, Huo, Da, Bo, Zheng, Deng, Zhu, Zhu, Biqing, Wang, Hengqi, Zhang, Qiang, Gentine, Pierre, and Liu, Zhu
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Physics - Atmospheric and Oceanic Physics ,Economics - General Economics - Abstract
Precise and high-resolution carbon dioxide (CO$_2$) emission data is of great importance of achieving the carbon neutrality around the world. Here we present for the first time the near-real-time Global Gridded Daily CO$_2$ Emission Datasets (called GRACED) from fossil fuel and cement production with a global spatial-resolution of 0.1$^\circ$ by 0.1$^\circ$ and a temporal-resolution of 1-day. Gridded fossil emissions are computed for different sectors based on the daily national CO$_2$ emissions from near real time dataset (Carbon Monitor), the spatial patterns of point source emission dataset Global Carbon Grid (GID), Emission Database for Global Atmospheric Research (EDGAR) and spatiotemporal patters of satellite nitrogen dioxide (NO$_2$) retrievals. Our study on the global CO$_2$ emissions responds to the growing and urgent need for high-quality, fine-grained near-real-time CO2 emissions estimates to support global emissions monitoring across various spatial scales. We show the spatial patterns of emission changes for power, industry, residential consumption, ground transportation, domestic and international aviation, and international shipping sectors between 2019 and 2020. This help us to give insights on the relative contributions of various sectors and provides a fast and fine-grained overview of where and when fossil CO$_2$ emissions have decreased and rebounded in response to emergencies (e.g. COVID-19) and other disturbances of human activities than any previously published dataset. As the world recovers from the pandemic and decarbonizes its energy systems, regular updates of this dataset will allow policymakers to more closely monitor the effectiveness of climate and energy policies and quickly adapt.
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- 2021
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15. Carbon Monitor Cities near-real-time daily estimates of CO2 emissions from 1500 cities worldwide
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Huo, Da, Huang, Xiaoting, Dou, Xinyu, Ciais, Philippe, Li, Yun, Deng, Zhu, Wang, Yilong, Cui, Duo, Benkhelifa, Fouzi, Sun, Taochun, Zhu, Biqing, Roest, Geoffrey, Gurney, Kevin R, Ke, Piyu, Guo, Rui, Lu, Chenxi, Lin, Xiaojuan, Lovell, Arminel, Appleby, Kyra, DeCola, Philip L, Davis, Steven J, and Liu, Zhu
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Built Environment and Design ,Urban and Regional Planning ,Sustainable Cities and Communities ,Climate Action - Abstract
Building on near-real-time and spatially explicit estimates of daily carbon dioxide (CO2) emissions, here we present and analyze a new city-level dataset of fossil fuel and cement emissions, Carbon Monitor Cities, which provides daily estimates of emissions from January 2019 through December 2021 for 1500 cities in 46 countries, and disaggregates five sectors: power generation, residential (buildings), industry, ground transportation, and aviation. The goal of this dataset is to improve the timeliness and temporal resolution of city-level emission inventories and includes estimates for both functional urban areas and city administrative areas that are consistent with global and regional totals. Comparisons with other datasets (i.e. CEADs, MEIC, Vulcan, and CDP-ICLEI Track) were performed, and we estimate the overall annual uncertainty range to be ±21.7%. Carbon Monitor Cities is a near-real-time, city-level emission dataset that includes cities around the world, including the first estimates for many cities in low-income countries.
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- 2022
16. Near-real-time global gridded daily CO2 emissions
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Dou, Xinyu, Wang, Yilong, Ciais, Philippe, Chevallier, Frédéric, Davis, Steven J, Crippa, Monica, Janssens-Maenhout, Greet, Guizzardi, Diego, Solazzo, Efisio, Yan, Feifan, Huo, Da, Zheng, Bo, Zhu, Biqing, Cui, Duo, Ke, Piyu, Sun, Taochun, Wang, Hengqi, Zhang, Qiang, Gentine, Pierre, Deng, Zhu, and Liu, Zhu
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Affordable and Clean Energy ,Climate Action ,2020 ,daily ,global change ,gridded CO2 emission ,near real time - Abstract
Precise and high-resolution carbon dioxide (CO2) emission data is of great importance in achieving carbon neutrality around the world. Here we present for the first time the near-real-time Global Gridded Daily CO2 Emissions Dataset (GRACED) from fossil fuel and cement production with a global spatial resolution of 0.1° by 0.1° and a temporal resolution of 1 day. Gridded fossil emissions are computed for different sectors based on the daily national CO2 emissions from near-real-time dataset (Carbon Monitor), the spatial patterns of point source emission dataset Global Energy Infrastructure Emissions Database (GID), Emission Database for Global Atmospheric Research (EDGAR), and spatiotemporal patters of satellite nitrogen dioxide (NO2) retrievals. Our study on the global CO2 emissions responds to the growing and urgent need for high-quality, fine-grained, near-real-time CO2 emissions estimates to support global emissions monitoring across various spatial scales. We show the spatial patterns of emission changes for power, industry, residential consumption, ground transportation, domestic and international aviation, and international shipping sectors from January 1, 2019, to December 31, 2020. This gives thorough insights into the relative contributions from each sector. Furthermore, it provides the most up-to-date and fine-grained overview of where and when fossil CO2 emissions have decreased and rebounded in response to emergencies (e.g., coronavirus disease 2019 [COVID-19]) and other disturbances of human activities of any previously published dataset. As the world recovers from the pandemic and decarbonizes its energy systems, regular updates of this dataset will enable policymakers to more closely monitor the effectiveness of climate and energy policies and quickly adapt.
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- 2022
17. Unprecedented decarbonization of China's power system in the post-COVID era
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Zhu, Biqing, Guo, Rui, Deng, Zhu, Zhao, Wenli, Ke, Piyu, Dou, Xinyu, Davis, Steven J., Ciais, Philippe, Gentine, Pierre, and Liu, Zhu
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Physics - Physics and Society ,Economics - General Economics ,Physics - Atmospheric and Oceanic Physics - Abstract
In October of 2020, China announced that it aims to start reducing its carbon dioxide (CO2) emissions before 2030 and achieve carbon neutrality before 20601. The surprise announcement came in the midst of the COVID-19 pandemic which caused a transient drop in China's emissions in the first half of 2020. Here, we show an unprecedented de-carbonization of China's power system in late 2020: although China's power related carbon emissions were 0.5% higher in 2020 than 2019, the majority (92.9%) of the increased power demand was met by increases in low-carbon (renewables and nuclear) generation (increased by 9.3%), as compared to only 0.4% increase for fossil fuels. China's low-carbon generation in the country grew in the second half of 2020, supplying a record high of 36.7% (increased by 1.9% compared to 2019) of total electricity in 2020, when the fossil production dropped to a historical low of 63.3%. Combined, the carbon intensity of China's power sector decreased to an historical low of 519.9 tCO2/GWh in 2020. If the fast decarbonization and slowed down power demand growth from 2019 to 2020 were to continue, by 2030, over half (50.8%) of China's power demand could be provided by low carbon sources. Our results thus reveal that China made progress towards its carbon neutrality target during the pandemic, and suggest the potential for substantial further decarbonization in the next few years if the latest trends persist.
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- 2021
18. Global Daily CO$_2$ emissions for the year 2020
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Liu, Zhu, Deng, Zhu, Ciais, Philippe, Tan, Jianguang, Zhu, Biqing, Davis, Steven J., Andrew, Robbie, Boucher, Olivier, Arous, Simon Ben, Canadel, Pep, Dou, Xinyu, Friedlingstein, Pierre, Gentine, Pierre, Guo, Rui, Hong, Chaopeng, Jackson, Robert B., Kammen, Daniel M., Ke, Piyu, Quere, Corinne Le, Monica, Crippa, Janssens-Maenhout, Greet, Peters, Glen, Tanaka, Katsumasa, Wang, Yilong, Zheng, Bo, Zhong, Haiwang, Sun, Taochun, and Schellnhuber, Hans Joachim
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Physics - Atmospheric and Oceanic Physics ,Economics - General Economics - Abstract
The diurnal cycle CO$_2$ emissions from fossil fuel combustion and cement production reflect seasonality, weather conditions, working days, and more recently the impact of the COVID-19 pandemic. Here, for the first time we provide a daily CO$_2$ emission dataset for the whole year of 2020 calculated from inventory and near-real-time activity data (called Carbon Monitor project: https://carbonmonitor.org). It was previously suggested from preliminary estimates that did not cover the entire year of 2020 that the pandemics may have caused more than 8% annual decline of global CO$_2$ emissions. Here we show from detailed estimates of the full year data that the global reduction was only 5.4% (-1,901 MtCO$_2$, ). This decrease is 5 times larger than the annual emission drop at the peak of the 2008 Global Financial Crisis. However, global CO$_2$ emissions gradually recovered towards 2019 levels from late April with global partial re-opening. More importantly, global CO$_2$ emissions even increased slightly by +0.9% in December 2020 compared with 2019, indicating the trends of rebound of global emissions. Later waves of COVID-19 infections in late 2020 and corresponding lockdowns have caused further CO$_2$ emissions reductions particularly in western countries, but to a much smaller extent than the declines in the first wave. That even substantial world-wide lockdowns of activity led to a one-time decline in global CO$_2$ emissions of only 5.4% in one year highlights the significant challenges for climate change mitigation that we face in the post-COVID era. These declines are significant, but will be quickly overtaken with new emissions unless the COVID-19 crisis is utilized as a break-point with our fossil-fuel trajectory, notably through policies that make the COVID-19 recovery an opportunity to green national energy and development plans.
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- 2021
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19. De-carbonization of global energy use during the COVID-19 pandemic
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Liu, Zhu, Zhu, Biqing, Ciais, Philippe, Davis, Steven J., Lu, Chenxi, Zhong, Haiwang, Ke, Piyu, Cui, Yanan, Deng, Zhu, Cui, Duo, Sun, Taochun, Dou, Xinyu, Tan, Jianguang, Guo, Rui, Zheng, Bo, Tanaka, Katsumasa, Zhao, Wenli, and Gentine, Pierre
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Physics - Atmospheric and Oceanic Physics ,Economics - General Economics ,Statistics - Other Statistics - Abstract
The COVID-19 pandemic has disrupted human activities, leading to unprecedented decreases in both global energy demand and GHG emissions. Yet a little known that there is also a low carbon shift of the global energy system in 2020. Here, using the near-real-time data on energy-related GHG emissions from 30 countries (about 70% of global power generation), we show that the pandemic caused an unprecedented de-carbonization of global power system, representing by a dramatic decrease in the carbon intensity of power sector that reached a historical low of 414.9 tCO2eq/GWh in 2020. Moreover, the share of energy derived from renewable and low-carbon sources (nuclear, hydro-energy, wind, solar, geothermal, and biomass) exceeded that from coal and oil for the first time in history in May of 2020. The decrease in global net energy demand (-1.3% in the first half of 2020 relative to the average of the period in 2016-2019) masks a large down-regulation of fossil-fuel-burning power plants supply (-6.1%) coincident with a surge of low-carbon sources (+6.2%). Concomitant changes in the diurnal cycle of electricity demand also favored low-carbon generators, including a flattening of the morning ramp, a lower midday peak, and delays in both the morning and midday load peaks in most countries. However, emission intensities in the power sector have since rebounded in many countries, and a key question for climate mitigation is thus to what extent countries can achieve and maintain lower, pandemic-level carbon intensities of electricity as part of a green recovery.
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- 2021
20. Urban public lighting classification method and analysis of energy and environmental effects based on SDGSAT-1 glimmer imager data
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Lv, Zhuoran, Guo, Huadong, Zhang, Lu, Liang, Dong, Zhu, Qi, Liu, Xuting, Zhou, Heng, Liu, Yiming, Gou, Yiting, Dou, Xinyu, and Chen, Guoqiang
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- 2024
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21. SPP1+ macrophages in colorectal cancer: Markers of malignancy and promising therapeutic targets
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Xie, Zhenyu, Zheng, Gaozan, Niu, Liaoran, Du, Kunli, Li, Ruikai, Dan, Hanjun, Duan, Lili, Wu, Hongze, Ren, Guangming, Dou, Xinyu, Dai, Songchen, Feng, Fan, Zhang, Jian, and Zheng, Jianyong
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- 2024
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22. Estimates of daily ground-level NO2 concentrations in China based on big data and machine learning approaches
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Dou, Xinyu, Liao, Cuijuan, Wang, Hengqi, Huang, Ying, Tu, Ying, Huang, Xiaomeng, Peng, Yiran, Zhu, Biqing, Tan, Jianguang, Deng, Zhu, Wu, Nana, Sun, Taochun, Ke, Piyu, and Liu, Zhu
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Physics - Atmospheric and Oceanic Physics ,Computer Science - Machine Learning - Abstract
Nitrogen dioxide (NO2) is one of the most important atmospheric pollutants. However, current ground-level NO2 concentration data are lack of either high-resolution coverage or full coverage national wide, due to the poor quality of source data and the computing power of the models. To our knowledge, this study is the first to estimate the ground-level NO2 concentration in China with national coverage as well as relatively high spatiotemporal resolution (0.25 degree; daily intervals) over the newest past 6 years (2013-2018). We advanced a Random Forest model integrated K-means (RF-K) for the estimates with multi-source parameters. Besides meteorological parameters, satellite retrievals parameters, we also, for the first time, introduce socio-economic parameters to assess the impact by human activities. The results show that: (1) the RF-K model we developed shows better prediction performance than other models, with cross-validation R2 = 0.64 (MAPE = 34.78%). (2) The annual average concentration of NO2 in China showed a weak increasing trend . While in the economic zones such as Beijing-Tianjin-Hebei region, Yangtze River Delta, and Pearl River Delta, the NO2 concentration there even decreased or remained unchanged, especially in spring. Our dataset has verified that pollutant controlling targets have been achieved in these areas. With mapping daily nationwide ground-level NO2 concentrations, this study provides timely data with high quality for air quality management for China. We provide a universal model framework to quickly generate a timely national atmospheric pollutants concentration map with a high spatial-temporal resolution, based on improved machine learning methods.
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- 2020
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23. Carbon Monitor: a near-real-time daily dataset of global CO2 emission from fossil fuel and cement production
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Liu, Zhu, Ciais, Philippe, Deng, Zhu, Davis, Steven J., Zheng, Bo, Wang, Yilong, Cui, Duo, Zhu, Biqing, Dou, Xinyu, Ke, Piyu, Sun, Taochun, Guo, Rui, Boucher, Olivier, Breon, Francois-Marie, Lu, Chenxi, Guo, Runtao, Boucher, Eulalie, and Chevallier, Frederic
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Physics - Physics and Society ,Economics - General Economics ,Physics - Atmospheric and Oceanic Physics ,Physics - Geophysics - Abstract
We constructed a near-real-time daily CO2 emission dataset, namely the Carbon Monitor, to monitor the variations of CO2 emissions from fossil fuel combustion and cement production since January 1st 2019 at national level with near-global coverage on a daily basis, with the potential to be frequently updated. Daily CO2 emissions are estimated from a diverse range of activity data, including: hourly to daily electrical power generation data of 29 countries, monthly production data and production indices of industry processes of 62 countries/regions, daily mobility data and mobility indices of road transportation of 416 cities worldwide. Individual flight location data and monthly data were utilised for aviation and maritime transportation sectors estimates. In addition, monthly fuel consumption data that corrected for daily air temperature of 206 countries were used for estimating the emissions from commercial and residential buildings. This Carbon Monitor dataset manifests the dynamic nature of CO2 emissions through daily, weekly and seasonal variations as influenced by workdays and holidays, as well as the unfolding impacts of the COVID-19 pandemic. The Carbon Monitor near-real-time CO2 emission dataset shows a 7.8% decline of CO2 emission globally from Jan 1st to Apr 30th in 2020 when compared with the same period in 2019, and detects a re-growth of CO2 emissions by late April which are mainly attributed to the recovery of economy activities in China and partial easing of lockdowns in other countries. Further, this daily updated CO2 emission dataset could offer a range of opportunities for related scientific research and policy making.
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- 2020
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24. COVID-19 causes record decline in global CO2 emissions
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Liu, Zhu, Ciais, Philippe, Deng, Zhu, Lei, Ruixue, Davis, Steven J., Feng, Sha, Zheng, Bo, Cui, Duo, Dou, Xinyu, He, Pan, Zhu, Biqing, Lu, Chenxi, Ke, Piyu, Sun, Taochun, Wang, Yuan, Yue, Xu, Wang, Yilong, Lei, Yadong, Zhou, Hao, Cai, Zhaonan, Wu, Yuhui, Guo, Runtao, Han, Tingxuan, Xue, Jinjun, Boucher, Olivier, Boucher, Eulalie, Chevallier, Frederic, Wei, Yimin, Zhong, Haiwang, Kang, Chongqing, Zhang, Ning, Chen, Bin, Xi, Fengming, Marie, François, Zhang, Qiang, Guan, Dabo, Gong, Peng, Kammen, Daniel M., He, Kebin, and Schellnhuber, Hans Joachim
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Economics - General Economics ,Physics - Geophysics ,Physics - Physics and Society - Abstract
The considerable cessation of human activities during the COVID-19 pandemic has affected global energy use and CO2 emissions. Here we show the unprecedented decrease in global fossil CO2 emissions from January to April 2020 was of 7.8% (938 Mt CO2 with a +6.8% of 2-{\sigma} uncertainty) when compared with the period last year. In addition other emerging estimates of COVID impacts based on monthly energy supply or estimated parameters, this study contributes to another step that constructed the near-real-time daily CO2 emission inventories based on activity from power generation (for 29 countries), industry (for 73 countries), road transportation (for 406 cities), aviation and maritime transportation and commercial and residential sectors emissions (for 206 countries). The estimates distinguished the decline of CO2 due to COVID-19 from the daily, weekly and seasonal variations as well as the holiday events. The COVID-related decreases in CO2 emissions in road transportation (340.4 Mt CO2, -15.5%), power (292.5 Mt CO2, -6.4% compared to 2019), industry (136.2 Mt CO2, -4.4%), aviation (92.8 Mt CO2, -28.9%), residential (43.4 Mt CO2, -2.7%), and international shipping (35.9Mt CO2, -15%). Regionally, decreases in China were the largest and earliest (234.5 Mt CO2,-6.9%), followed by Europe (EU-27 & UK) (138.3 Mt CO2, -12.0%) and the U.S. (162.4 Mt CO2, -9.5%). The declines of CO2 are consistent with regional nitrogen oxides concentrations observed by satellites and ground-based networks, but the calculated signal of emissions decreases (about 1Gt CO2) will have little impacts (less than 0.13ppm by April 30, 2020) on the overserved global CO2 concertation. However, with observed fast CO2 recovery in China and partial re-opening globally, our findings suggest the longer-term effects on CO2 emissions are unknown and should be carefully monitored using multiple measures.
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- 2020
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25. Prognostic value of normal levels of preoperative tumor markers in colorectal cancer
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Ren, Guangming, Li, Ruikai, Zheng, Gaozan, Du, Kunli, Dan, Hanjun, Wu, Hongze, Dou, Xinyu, Duan, Lili, Xie, Zhenyu, Niu, Liaoran, Tian, Ye, Zheng, Jianyong, and Feng, Fan
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- 2023
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26. Single-cell analysis unveils activation of mast cells in colorectal cancer microenvironment
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Xie, Zhenyu, Niu, Liaoran, Zheng, Gaozan, Du, Kunli, Dai, Songchen, Li, Ruikai, Dan, Hanjun, Duan, Lili, Wu, Hongze, Ren, Guangming, Dou, Xinyu, Feng, Fan, Zhang, Jian, and Zheng, Jianyong
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- 2023
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27. Selective photoelectrochemical oxidation of glucose to glucaric acid by single atom Pt decorated defective TiO2
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Tian, Zhangliu, Da, Yumin, Wang, Meng, Dou, Xinyu, Cui, Xinhang, Chen, Jie, Jiang, Rui, Xi, Shibo, Cui, Baihua, Luo, Yani, Yang, Haotian, Long, Yu, Xiao, Yukun, and Chen, Wei
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- 2023
- Full Text
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28. Dynamic landscapes and the influence of human activities in the Yellow River Delta wetland region
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Dou, Xinyu, Guo, Huadong, Zhang, Lu, Liang, Dong, Zhu, Qi, Liu, Xuting, Zhou, Heng, Lv, Zhuoran, Liu, Yiming, Gou, Yiting, and Wang, Zhoulong
- Published
- 2023
- Full Text
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29. The Discussion on Shannon channel capacity formula from the viewpoint of signal uncertainty and Research on the Technique of Breaking through the Shannon Limit
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Liang, Dequn and Dou, Xinyu
- Subjects
Computer Science - Information Theory ,Electrical Engineering and Systems Science - Signal Processing - Abstract
In this paper, firstly, the Shannon channel capacity formula is briefly stated, and the relationship between the formula and the signal uncertainty principle is analyzed in order to prepare for deriving the formula which is able to break through the Shannon channel capacity. Then, as a practical example of breaking the Shannon limit, the time-shift non orthogonal multicarrier modulation technology is introduced. After more than twenty years of development, this technique is proved to be a practical modulation technique for digital communication.
- Published
- 2019
30. Author Correction: Near-real-time monitoring of global CO2 emissions reveals the effects of the COVID-19 pandemic.
- Author
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Liu, Zhu, Ciais, Philippe, Deng, Zhu, Lei, Ruixue, Davis, Steven J, Feng, Sha, Zheng, Bo, Cui, Duo, Dou, Xinyu, Zhu, Biqing, Guo, Rui, Ke, Piyu, Sun, Taochun, Lu, Chenxi, He, Pan, Wang, Yuan, Yue, Xu, Wang, Yilong, Lei, Yadong, Zhou, Hao, Cai, Zhaonan, Wu, Yuhui, Guo, Runtao, Han, Tingxuan, Xue, Jinjun, Boucher, Olivier, Boucher, Eulalie, Chevallier, Frédéric, Tanaka, Katsumasa, Wei, Yiming, Zhong, Haiwang, Kang, Chongqing, Zhang, Ning, Chen, Bin, Xi, Fengming, Liu, Miaomiao, Bréon, François-Marie, Lu, Yonglong, Zhang, Qiang, Guan, Dabo, Gong, Peng, Kammen, Daniel M, He, Kebin, and Schellnhuber, Hans Joachim
- Abstract
A Correction to this paper has been published: https://doi.org/10.1038/s41467-020-20254-5.
- Published
- 2020
31. Near-real-time monitoring of global CO2 emissions reveals the effects of the COVID-19 pandemic.
- Author
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Liu, Zhu, Ciais, Philippe, Deng, Zhu, Lei, Ruixue, Davis, Steven J, Feng, Sha, Zheng, Bo, Cui, Duo, Dou, Xinyu, Zhu, Biqing, Guo, Rui, Ke, Piyu, Sun, Taochun, Lu, Chenxi, He, Pan, Wang, Yuan, Yue, Xu, Wang, Yilong, Lei, Yadong, Zhou, Hao, Cai, Zhaonan, Wu, Yuhui, Guo, Runtao, Han, Tingxuan, Xue, Jinjun, Boucher, Olivier, Boucher, Eulalie, Chevallier, Frédéric, Tanaka, Katsumasa, Wei, Yiming, Zhong, Haiwang, Kang, Chongqing, Zhang, Ning, Chen, Bin, Xi, Fengming, Liu, Miaomiao, Bréon, François-Marie, Lu, Yonglong, Zhang, Qiang, Guan, Dabo, Gong, Peng, Kammen, Daniel M, He, Kebin, and Schellnhuber, Hans Joachim
- Subjects
Humans ,Pneumonia ,Viral ,Coronavirus Infections ,Carbon Dioxide ,Nitrogen Dioxide ,Air Pollutants ,Fossil Fuels ,Environmental Monitoring ,Industry ,Pandemics ,Betacoronavirus ,COVID-19 ,SARS-CoV-2 - Abstract
The COVID-19 pandemic is impacting human activities, and in turn energy use and carbon dioxide (CO2) emissions. Here we present daily estimates of country-level CO2 emissions for different sectors based on near-real-time activity data. The key result is an abrupt 8.8% decrease in global CO2 emissions (-1551 Mt CO2) in the first half of 2020 compared to the same period in 2019. The magnitude of this decrease is larger than during previous economic downturns or World War II. The timing of emissions decreases corresponds to lockdown measures in each country. By July 1st, the pandemic's effects on global emissions diminished as lockdown restrictions relaxed and some economic activities restarted, especially in China and several European countries, but substantial differences persist between countries, with continuing emission declines in the U.S. where coronavirus cases are still increasing substantially.
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- 2020
32. Global patterns of daily CO2 emissions reductions in the first year of COVID-19
- Author
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Liu, Zhu, Deng, Zhu, Zhu, Biqing, Ciais, Philippe, Davis, Steven J., Tan, Jianguang, Andrew, Robbie M., Boucher, Olivier, Arous, Simon Ben, Canadell, Josep G., Dou, Xinyu, Friedlingstein, Pierre, Gentine, Pierre, Guo, Rui, Hong, Chaopeng, Jackson, Robert B., Kammen, Daniel M., Ke, Piyu, Le Quéré, Corinne, Monica, Crippa, Janssens-Maenhout, Greet, Peters, Glen P., Tanaka, Katsumasa, Wang, Yilong, Zheng, Bo, Zhong, Haiwang, Sun, Taochun, and Schellnhuber, Hans Joachim
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- 2022
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33. Scenarios of demographic distributional aspects of health co-benefits from decarbonising urban transport
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Lu, Chenxi, Adger, W Neil, Morrissey, Karyn, Zhang, Shaohui, Venevsky, Sergey, Yin, Hao, Sun, Taochun, Song, Xuanren, Wu, Chao, Dou, Xinyu, Zhu, Biqing, and Liu, Zhu
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- 2022
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34. Biomimetic Porous Ti6Al4V Implants: A Novel Interbody Fusion Cage via Gel‐Casting Technique to Promote Spine Fusion.
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Dou, Xinyu, Liu, Xiao, Liu, Yu, Wang, Linbang, Jia, Fei, Shen, Fei, Ma, Yunlong, Liang, Chen, Jin, Gong, Wang, Meina, Liu, Zhongjun, Zhu, Bin, and Liu, Xiaoguang
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- 2024
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35. Simulation Research on the Dual-Electrode Current Excitation Method for Distance Measurements While Drilling.
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Dou, Xinyu, Yan, Xiaoping, Hu, Longyu, and Liang, Huaqing
- Subjects
DRILLING platforms ,NUMERICAL calculations ,MAGNETIC traps ,MAGNETIC fields ,AZIMUTH - Abstract
Featured Application: A novel active range while drilling method, based on the drilling well, with dual-electrode current excitation, is proposed. The range while drilling model utilizing dual-electrode current excitation is established, and the calculation methods for the current amplitude of the casing and the formation-induced magnetic field distribution are derived. The accuracy and effectiveness of this approach are validated through numerical calculations and simulation analyses of the impact of each key factor. It is particularly appropriate for targeted well ranging operations that entail safety risks, especially in the relief well connectivity operations at space-constrained drilling platforms. Based on a comprehensive analysis of the existing methods for measuring adjacent well distances, along with their advantages and disadvantages, this study employs theoretical analysis, simulation experiments, and other comprehensive research methods to investigate a distance measurement method based on current excitation. In response to the need for measuring and controlling the connection of relief wells, a method utilizing dual-electrode current excitation during drilling is proposed. This approach facilitates synchronous excitation measurements while drilling, significantly reducing both time and costs while ensuring safety and efficiency, making it particularly suitable for the connection operation of relief wells that involve safety risks. Firstly, this paper establishes a drilling with measurement model corresponding to the excitation mode, which derives the calculation formulas for the target casing current amplitude attenuation, as well as the induced magnetic field distribution within the formation. Additionally, it provides the calculation methods for determining the target well distance and azimuth direction. Lastly, the impact levels of various key factors are verified through numerical calculations and simulation analyses, which confirm the correctness and effectiveness of this distance measurement method. The findings from this research establish both a core theoretical foundation and a technological basis for the real-time measurement of adjacent well distances during relief well operations. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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36. Differences in Anthropogenic Impacts of Typical Mid- to High-Latitude Wetlands in the Heilongjiang Basin.
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Liu, Jinlong, Dou, Xinyu, Zhang, Lu, Liang, Dong, Zhu, Qi, Lv, Zhuoran, Liu, Yiming, and Du, Xiaobing
- Abstract
Wetlands represent one of the three principal ecosystems and serve a vital function in the protection of water resources and the regulation of climate. However, wetlands are currently experiencing significant challenges, particularly in the agriculturally productive wetlands of the Heilongjiang River Basin, which have been considerably impacted by human activities. This study focuses on three representative wetlands situated within the Heilongjiang River Basin. This study analyses changes in wetland area and landscape patterns from 2002 to 2022, as well as the impact of agriculture and impervious surface expansion on the wetlands. The findings indicate that agricultural expansion is the primary driver of wetland area loss. The wetland area affected by agriculture demonstrates the most significant change, with the largest observed shift reaching 47.2%. The expansion of impervious surfaces was found to have a significant impact on wetland fragmentation, resulting in a notable decrease in wetland connectivity. This was evidenced by a reduction in the average patch size, which decreased by 14.68 ha over the decade from 2007 to 2017, a period during which impervious surfaces expanded. This paper identifies the distinctions in the influence of diverse human activities on wetland landscape patterns in the Heilongjiang Basin and employs natural samples for control, thereby attenuating the impact of the natural environment. This study offers a novel perspective on the processes of wetland change and the maintenance of wetland health, which is crucial for the realisation of clean water and sanitation (Sustainable Development Goal 6.6). [ABSTRACT FROM AUTHOR]
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- 2024
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37. Research on GNSS Time Series Noise Reduction Combining Principal Component Decomposition and Compound Evaluation Index
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Li, Xinrui, Zhang, Shuangcheng, Dong, Zhiqiang, Dou, Xinyu, Xue, Yiming, Wang, Lixia, Zhong, Chuhan, Hao, Yunqing, Bai, Qintao, Li, Pingli, Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Jiming, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Hirche, Sandra, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Li, Yong, Series Editor, Liang, Qilian, Series Editor, Martín, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Möller, Sebastian, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zhang, Junjie James, Series Editor, Yang, Changfeng, editor, and Xie, Jun, editor
- Published
- 2021
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38. GNSS-R Interpretation of Soil Moisture Scattering Characteristics Simulation Research
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Ma, Zhongmin, Zhang, Shuangcheng, Liu, Qi, Peng, Jilun, Dou, Xinyu, Xue, Yiming, Ma, Boyuan, Chen, Xingtong, Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Jiming, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Hirche, Sandra, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Li, Yong, Series Editor, Liang, Qilian, Series Editor, Martín, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Möller, Sebastian, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zhang, Junjie James, Series Editor, Yang, Changfeng, editor, and Xie, Jun, editor
- Published
- 2021
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39. An active magnetic ranging method for drilling cluster wells based on casing current excitation
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Yan, Xiaoping, Liang, Huaqing, Dou, Xinyu, Qing, Meiyi, and Cao, Xudong
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- 2022
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40. Can free-view media processing technology improve classroom performance?
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Dou, Xinyu, primary
- Published
- 2024
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41. Numerical Implementation of a Wideband Chaotic Light Based Ring-and-Spur Long-Reach Passive Optical Network: Architectures and Real-Time Secure Communications
- Author
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Dou, Xinyu, Yin, Hongxi, Wu, Bin, Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Jiming, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Hirche, Sandra, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Liang, Qilian, Series Editor, Martín, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Möller, Sebastian, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zhang, Junjie James, Series Editor, Liu, Xin, editor, Na, Zhenyu, editor, Wang, Wei, editor, Mu, Jiasong, editor, and Zhang, Baoju, editor
- Published
- 2020
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42. The linkage cultivation of creative thinking and innovative thinking in dance choreography
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Dou, Xinyu, Li, Hanjin, and Jia, Lin
- Published
- 2021
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43. A Time-Delay Overlapping Modulation-Based High Spectral Efficiency Multi-User Differential Chaos Shift Keying for Maritime Internet of Vessels
- Author
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Dou, Xinyu, Lyu, Tengxiao, Han, Tuoyu, and Liang, Dequn
- Abstract
The scarce maritime spectrum resource prevents the maritime communication network from carrying more users. In this letter, an offshore multi-user differential chaos shift keying scheme based on the time-delay overlapping modulation (TDOM-MUDCSK) is proposed. The TDOM technique can use the bandwidth of a single subcarrier to carry information bits. Thus, the bandwidth occupied by all users can be significantly reduced, indicating that the maritime communication network can accommodate more users based on the saved spectrum resource. The multi-user communication mechanism and system structure for both downlink and uplink communication scenarios are designed, and the spectrum efficiency and complexity are analyzed. In addition, the BER expression under the maritime communication channel is derived, and a method to weaken inter-carrier-interference (ICI) is demonstrated. Simulation results verify the theoretical derivations and show the superiority of the system.
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- 2024
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44. Global and local carbon footprints of city of Hong Kong and Macao from 2000 to 2015
- Author
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Dou, Xinyu, Deng, Zhu, Sun, Taochun, Ke, Piyu, Zhu, Biqing, Shan, Yuli, and Liu, Zhu
- Published
- 2021
- Full Text
- View/download PDF
45. Who is a good neighbor? Analysis of frontrunner cities with comparative advantages in low-carbon development
- Author
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Wang, Zhen, Dou, Xinyu, Wu, Pengcheng, Liang, Sen, Cai, Bofeng, Cao, Libin, Pang, Lingyun, Bo, Xin, and Wei, Liyuan
- Published
- 2020
- Full Text
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46. Osteogenesis or Apoptosis─Twofold Effects of Zn2+ on Bone Marrow Mesenchymal Stem Cells: An In Vitro and In Vivo Study
- Author
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Liu, Yu, primary, Wang, Linbang, additional, Dou, Xinyu, additional, Du, Mingze, additional, Min, Shuyuan, additional, Zhu, Bin, additional, and Liu, Xiaoguang, additional
- Published
- 2024
- Full Text
- View/download PDF
47. The aid of ChatGPT to dance education: a theoretical exploration based on TPACK.
- Author
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Dou, Xinyu
- Subjects
- *
DANCE education , *CHATGPT , *PERCEPTUAL learning , *MENTORING , *PEDAGOGICAL content knowledge , *DANCE techniques - Abstract
This in-depth exploration delves into the transformative possibilities of integrating ChatGPT into the realm of dance education. Examining its roles as a learning ally, creative mentor, knowledge transmitter, and perceptual guide within the unique context of dance instruction, the study navigates through the Technological Pedagogical Content Knowledge (TPACK) framework. It showcases how ChatGPT can elevate teaching efficiency, provide real-time feedback on dance movements, kindle artistic curiosity, and extend emotional support to students. While emphasizing its positive impact, the study also acknowledges potential risks, underscoring the irreplaceable role of educators in guiding students on effective ChatGPT utilization, ensuring it complements the nuanced aspects of dance education. The supporting framework presented highlights the dynamic synergy between ChatGPT, educators, and students, promising a more engaging and enriched dance education experience. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
48. Development of a Minimum Dataset for the Monitoring of Recombinant Human Growth Hormone Therapy in Children with Growth Hormone Deficiency: A GloBE-Reg Initiative.
- Author
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Chen, Suet Ching, Bryce, Jillian, Chen, Minglu, Charmandari, Evangelia, Choi, Jin-Ho, Dou, Xinyu, Gong, Chunxiu, Hamza, Rasha, Harvey, Jamie, Hoffman, Andrew R., Horikawa, Reiko, Johannson, Gudmundur, Jorge, Alexander Augusto de Lima, Miller, Bradley S., Roehrich, Sebastian, Sävendahl, Lars, Tseretopoulou, Xanthippi, Vitali, Diana, Wajnrajch, Michael, and Ahmed, S.Faisal
- Subjects
HUMAN growth hormone ,GROWTH of children ,HORMONE therapy ,SOMATOTROPIN ,DRUG efficacy - Abstract
Introduction: Although there are some recommendations in the literature on the assessments that should be performed in children on recombinant human growth hormone (rhGH) therapy, the level of consensus on these measurements is not clear. The objective of the current study was to identify the minimum dataset (MDS) that could be measured in a routine clinical setting across the world, aiming to minimise burden on clinicians and improve quality of data collection. Methods: This study was undertaken by the growth hormone (GH) scientific study group in GloBE-Reg, a new project that has developed a common registry platform that can support long-term safety and effectiveness studies of drugs. Twelve clinical experts from 7 international endocrine organisations identified by the GloBE-Reg Steering Committee, 2 patient representatives, and representatives from 2 pharmaceutical companies with previous GH registry expertise collaborated to develop this recommendation. A comprehensive list of data fields routinely collected by each of the clinical and industry experts for children with growth hormone deficiency (GHD) was compiled. Each member was asked to determine the: (1) importance of the data field and (2) ease of data collection. Data fields that achieved 70% consensus in terms of importance qualified for the MDS, provided <50% deemed the item difficult to collect. Results: A total of 246 items were compiled and 27 were removed due to redundancies, with 219 items subjected to the grading system. Of the 219 items, 111 achieved at least 70% consensus as important data to collect when monitoring children with GHD on rhGH treatment. Sixty-nine of the 219 items were deemed easy to collect. Combining the criteria of importance and ease of data collection, 63 met the criteria for the MDS. Several anomalies to the MDS rule were identified and highlighted for discussion, including whether the patients were involved in current or previous clinical trials, need for HbA1c monitoring, other past medical history, and adherence, enabling formulation of the final MDS recommendation of 43 items; 20 to be completed once, 14 every 6 months, and 9 every 12 months. Conclusion: In summary, this exercise performed through the GloBE-Reg initiative provides a recommendation of the MDS requirement, collected through real-world data, for the monitoring of safety and effectiveness of rhGH in children with GHD, both for the current daily preparations and the newer long-acting GH. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
49. Global Carbon Budget 2023
- Author
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Friedlingstein, Pierre, primary, O'Sullivan, Michael, additional, Jones, Matthew W., additional, Andrew, Robbie M., additional, Bakker, Dorothee C. E., additional, Hauck, Judith, additional, Landschützer, Peter, additional, Le Quéré, Corinne, additional, Luijkx, Ingrid T., additional, Peters, Glen P., additional, Peters, Wouter, additional, Pongratz, Julia, additional, Schwingshackl, Clemens, additional, Sitch, Stephen, additional, Canadell, Josep G., additional, Ciais, Philippe, additional, Jackson, Robert B., additional, Alin, Simone R., additional, Anthoni, Peter, additional, Barbero, Leticia, additional, Bates, Nicholas R., additional, Becker, Meike, additional, Bellouin, Nicolas, additional, Decharme, Bertrand, additional, Bopp, Laurent, additional, Brasika, Ida Bagus Mandhara, additional, Cadule, Patricia, additional, Chamberlain, Matthew A., additional, Chandra, Naveen, additional, Chau, Thi-Tuyet-Trang, additional, Chevallier, Frédéric, additional, Chini, Louise P., additional, Cronin, Margot, additional, Dou, Xinyu, additional, Enyo, Kazutaka, additional, Evans, Wiley, additional, Falk, Stefanie, additional, Feely, Richard A., additional, Feng, Liang, additional, Ford, Daniel J., additional, Gasser, Thomas, additional, Ghattas, Josefine, additional, Gkritzalis, Thanos, additional, Grassi, Giacomo, additional, Gregor, Luke, additional, Gruber, Nicolas, additional, Gürses, Özgür, additional, Harris, Ian, additional, Hefner, Matthew, additional, Heinke, Jens, additional, Houghton, Richard A., additional, Hurtt, George C., additional, Iida, Yosuke, additional, Ilyina, Tatiana, additional, Jacobson, Andrew R., additional, Jain, Atul, additional, Jarníková, Tereza, additional, Jersild, Annika, additional, Jiang, Fei, additional, Jin, Zhe, additional, Joos, Fortunat, additional, Kato, Etsushi, additional, Keeling, Ralph F., additional, Kennedy, Daniel, additional, Klein Goldewijk, Kees, additional, Knauer, Jürgen, additional, Korsbakken, Jan Ivar, additional, Körtzinger, Arne, additional, Lan, Xin, additional, Lefèvre, Nathalie, additional, Li, Hongmei, additional, Liu, Junjie, additional, Liu, Zhiqiang, additional, Ma, Lei, additional, Marland, Greg, additional, Mayot, Nicolas, additional, McGuire, Patrick C., additional, McKinley, Galen A., additional, Meyer, Gesa, additional, Morgan, Eric J., additional, Munro, David R., additional, Nakaoka, Shin-Ichiro, additional, Niwa, Yosuke, additional, O'Brien, Kevin M., additional, Olsen, Are, additional, Omar, Abdirahman M., additional, Ono, Tsuneo, additional, Paulsen, Melf, additional, Pierrot, Denis, additional, Pocock, Katie, additional, Poulter, Benjamin, additional, Powis, Carter M., additional, Rehder, Gregor, additional, Resplandy, Laure, additional, Robertson, Eddy, additional, Rödenbeck, Christian, additional, Rosan, Thais M., additional, Schwinger, Jörg, additional, Séférian, Roland, additional, Smallman, T. Luke, additional, Smith, Stephen M., additional, Sospedra-Alfonso, Reinel, additional, Sun, Qing, additional, Sutton, Adrienne J., additional, Sweeney, Colm, additional, Takao, Shintaro, additional, Tans, Pieter P., additional, Tian, Hanqin, additional, Tilbrook, Bronte, additional, Tsujino, Hiroyuki, additional, Tubiello, Francesco, additional, van der Werf, Guido R., additional, van Ooijen, Erik, additional, Wanninkhof, Rik, additional, Watanabe, Michio, additional, Wimart-Rousseau, Cathy, additional, Yang, Dongxu, additional, Yang, Xiaojuan, additional, Yuan, Wenping, additional, Yue, Xu, additional, Zaehle, Sönke, additional, Zeng, Jiye, additional, and Zheng, Bo, additional
- Published
- 2023
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50. Supplementary material to "Global Carbon Budget 2023"
- Author
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Friedlingstein, Pierre, primary, O'Sullivan, Michael, additional, Jones, Matthew W., additional, Andrew, Robbie M., additional, Bakker, Dorothee C. E., additional, Hauck, Judith, additional, Landschützer, Peter, additional, Le Quéré, Corinne, additional, Luijkx, Ingrid T., additional, Peters, Glen P., additional, Peters, Wouter, additional, Pongratz, Julia, additional, Schwingshackl, Clemens, additional, Sitch, Stephen, additional, Canadell, Josep G., additional, Ciais, Philippe, additional, Jackson, Robert B., additional, Alin, Simone R., additional, Anthoni, Peter, additional, Barbero, Leticia, additional, Bates, Nicholas R., additional, Becker, Meike, additional, Bellouin, Nicolas, additional, Decharme, Bertrand, additional, Bopp, Laurent, additional, Brasika, Ida Bagus Mandhara, additional, Cadule, Patricia, additional, Chamberlain, Matthew A., additional, Chandra, Naveen, additional, Chau, Thi-Tuyet-Trang, additional, Chevallier, Frédéric, additional, Chini, Louise P., additional, Cronin, Margot, additional, Dou, Xinyu, additional, Enyo, Kazutaka, additional, Evans, Wiley, additional, Falk, Stefanie, additional, Feely, Richard A., additional, Feng, Liang, additional, Ford, Daniel. J., additional, Gasser, Thomas, additional, Ghattas, Josefine, additional, Gkritzalis, Thanos, additional, Grassi, Giacomo, additional, Gregor, Luke, additional, Gruber, Nicolas, additional, Gürses, Özgür, additional, Harris, Ian, additional, Hefner, Matthew, additional, Heinke, Jens, additional, Houghton, Richard A., additional, Hurtt, George C., additional, Iida, Yosuke, additional, Ilyina, Tatiana, additional, Jacobson, Andrew R., additional, Jain, Atul, additional, Jarníková, Tereza, additional, Jersild, Annika, additional, Jiang, Fei, additional, Jin, Zhe, additional, Joos, Fortunat, additional, Kato, Etsushi, additional, Keeling, Ralph F., additional, Kennedy, Daniel, additional, Klein Goldewijk, Kees, additional, Knauer, Jürgen, additional, Korsbakken, Jan Ivar, additional, Körtzinger, Arne, additional, Lan, Xin, additional, Lefèvre, Nathalie, additional, Li, Hongmei, additional, Liu, Junjie, additional, Liu, Zhiqiang, additional, Ma, Lei, additional, Marland, Greg, additional, Mayot, Nicolas, additional, McGuire, Patrick C., additional, McKinley, Galen A., additional, Meyer, Gesa, additional, Morgan, Eric J., additional, Munro, David R., additional, Nakaoka, Shin-Ichiro, additional, Niwa, Yosuke, additional, O'Brien, Kevin M., additional, Olsen, Are, additional, Omar, Abdirahman M., additional, Ono, Tsuneo, additional, Paulsen, Melf E., additional, Pierrot, Denis, additional, Pocock, Katie, additional, Poulter, Benjamin, additional, Powis, Carter M., additional, Rehder, Gregor, additional, Resplandy, Laure, additional, Robertson, Eddy, additional, Rödenbeck, Christian, additional, Rosan, Thais M., additional, Schwinger, Jörg, additional, Séférian, Roland, additional, Smallman, T. Luke, additional, Smith, Stephen M., additional, Sospedra-Alfonso, Reinel, additional, Sun, Qing, additional, Sutton, Adrienne J., additional, Sweeney, Colm, additional, Takao, Shintaro, additional, Tans, Pieter P., additional, Tian, Hanqin, additional, Tilbrook, Bronte, additional, Tsujino, Hiroyuki, additional, Tubiello, Francesco, additional, van der Werf, Guido R., additional, van Ooijen, Erik, additional, Wanninkhof, Rik, additional, Watanabe, Michio, additional, Wimart-Rousseau, Cathy, additional, Yang, Dongxu, additional, Yang, Xiaojuan, additional, Yuan, Wenping, additional, Yue, Xu, additional, Zaehle, Sönke, additional, Zeng, Jiye, additional, and Zheng, Bo, additional
- Published
- 2023
- Full Text
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