95 results on '"Dowling, James E."'
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2. Therapeutic Potential of Alpha V Integrin Antagonists in TGFβ-Driven Disease
3. Optimization of a Series of Novel, Potent and Selective Macrocyclic SYK Inhibitors
4. Optimization of a series of novel, potent and selective Macrocyclic SYK inhibitors
5. Improving HIV Surveillance Data by Using the ATra Black Box System to Assist Regional Deduplication Activities
6. Abstract 10717: Role of Integrin Signaling in Pulmonary Arterial Hypertension
7. Abstract 1559: Inhibition of integrin αvβ8 enhances immune checkpoint induced anti-tumor immunity by acting across immunologic synapse in syngeneic models of breast cancer
8. Optimization of a series of potent, selective and orally bioavailable SYK inhibitors
9. Identification of a novel series of azabenzimidazole-derived inhibitors of spleen tyrosine kinase
10. Integrin alphaVbeta1 inhibition ameliorates liver fibrosis in mice
11. Synthesis of 2,4-diamino-5,6,7,8,9,10-hexahydro-5,9-methanopyrimido[4,5-b]azocine
12. Replacement of the 1'4,'-phenylene region in 5,10-dideaza-5,6,7,8-tetrahydrofolic acid (DDATHF) by 4,5,6,7-tetrahydrobenzo(c)thiophene and 4,5,6,7-tetrahydroisobenzofuran nuclei
13. Discovery of 2,6-disubstituted pyrazine derivatives as inhibitors of CK2 and PIM kinases
14. Discovery and Optimization of Pyrrolopyrimidine Inhibitors of Interleukin-1 Receptor Associated Kinase 4 (IRAK4) for the Treatment of Mutant MYD88L265PDiffuse Large B-Cell Lymphoma
15. Determining direct binders of the Androgen Receptor using a high-throughput Cellular Thermal Shift Assay
16. Discovery and Optimization of Pyrrolopyrimidine Inhibitors of Interleukin-1 Receptor Associated Kinase 4 (IRAK4) for the Treatment of Mutant MYD88L265P Diffuse Large B-Cell Lymphoma
17. Cover Picture: Target Deconvolution Efforts on Wnt Pathway Screen Reveal Dual Modulation of Oxidative Phosphorylation and SERCA2 (ChemMedChem 12/2017)
18. Target Deconvolution Efforts on Wnt Pathway Screen Reveal Dual Modulation of Oxidative Phosphorylation and SERCA2
19. Optimization of Highly Kinase Selective Bis-anilino Pyrimidine PAK1 Inhibitors
20. Potent and Selective CK2 Kinase Inhibitors with Effects on Wnt Pathway Signaling in Vivo
21. Abstract B47: Potent and selective CK2 kinase inhibitors with effects on Wnt pathway signaling in vivo
22. Discovery and Optimization of Pyrrolopyrimidine Inhibitors of Interleukin-1 Receptor Associated Kinase 4 (IRAK4) for the Treatment of Mutant MYD88L265P Diffuse Large B-Cell Lymphoma.
23. Discovery of novel benzylidene-1,3-thiazolidine-2,4-diones as potent and selective inhibitors of the PIM-1, PIM-2, and PIM-3 protein kinases
24. Discovery of Potent KIFC1 Inhibitors Using a Method of Integrated High-Throughput Synthesis and Screening
25. Identification and optimisation of 7-azaindole PAK1 inhibitors with improved potency and kinase selectivity
26. Structure and Property Based Design of Pyrazolo[1,5-a]pyrimidine Inhibitors of CK2 Kinase with Activity in Vivo
27. Abstract 2353: Novel inhibitors of PIM-1, PIM-2, and PIM-3 protein kinases: medicinal chemistry leading to AZD1208.
28. Abstract 3770: PK/PD/Efficacy characterization of AZ285, a selective CK2 kinase inhibitor
29. Abstract 3907: Discovery and characterization of AZ285 as a potent and selective inhibitor of CK2 kinase
30. Potent and Selective Inhibitors of CK2 Kinase Identified through Structure-Guided Hybridization
31. ChemInform Abstract: Synthesis of 2,4-Diamino-5,6,7,8,9,10-hexahydro-5,9-methanopyrimido[4,5-b]azocine.
32. Discovery of Potent KIFC1Inhibitors Using a Methodof Integrated High-Throughput Synthesis and Screening.
33. Potent and Orally Bioavailable 8-Bicyclo[2.2.2]octylxanthines as Adenosine A1 Receptor Antagonists
34. Synthesis of [1,2,4]Triazolo[1,5-a]pyrazines as Adenosine A2A Receptor Antagonists.
35. Synthesis of [1,2,4]triazolo[1,5-a]pyrazines as adenosine A2A receptor antagonists
36. Synthesis of [1,2,4]triazolo[1,5- a]pyrazines as adenosine A 2A receptor antagonists
37. Synthesis of 2,4-Diamino-5,6,7,8,9,10-hexahydro-5,9-methanopyrimido[4,5-b]azocine
38. Unexpected and facile bridgehead substitution in 5,6,7,8,9,10-hexahydro-5,9-methano-pyrimido[4,5-]azocin-4(3)-ones
39. Synthesis of a pyrimido[4,5-b]azepine analog of 5,10-dideaza-5,6,7,8-tetrahydrofolic acid (DDATHF)
40. Index.
41. 2,1-Benzisoxazoles.
42. Partially Saturated Polynuclear Isoxazoles.
43. Heterocycles Condensed to the Isoxazole Ring.
44. Frontmatter.
45. 1,2-Benzisoxazoles.
46. Cyclization and cycloaddition of 1-cinnamylidene-5-phenyl-3-oxopyrazolidinium ylide
47. Benzylation of 1‐Benzylidene‐3‐Pyrazolidinium Oxides
48. Synthesis of [1,2,4]triazolo[1,5-a]pyrazines as adenosine A2A receptor antagonists
49. Rotational matched spatial filter for biological pattern recognition
50. Synthesis of [1,2,4]Triazolo[1,5-a]pyrazines as Adenosine A2A Receptor Antagonists.
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