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Background: Down syndrome is a genetic condition brought on by the existence of a third copy of chromosome 2 1 in whole or in part. Even though, it is frequently linked to mild to severe physical growth delays and distinctive facial traits. However, some students in Rome receive their education in regular schools, others need a more specialized education where some people with DS complete their high school education where a small number continue their education after that. Objective: This paper aims to conduct a cross-sectional study in Iraq to know the outcomes of lipid profiles in patients with Down syndrome of children. Patients and Methods: Data were collected retrospectively through reviews of electronic medical records or electronic hospital records, and discharge data for all Down syndrome patients from different hospitals in Iraq between 3rd Jun 2021 to 7th July 2022, who were children among all patients who underwent procedures. These data were designed with two groups where the first group was represented with Down syndrome patients who have 40 patients while the second group represented control who contain 30. A statistical study was conducted for patients using the SPSS program. Discussion: The study includes 40 Down syndrome patients between the ages of 5 and 10 years, with 8.5±2.5 of the control group. Data on the distribution of patients' indicator values in obese 7 (17.5 %) for Down syndrome patients while 6 (20 %) for the control and overweight child ren for Down syndrome patients 15 (37.5 %) while 3 (I0 %) for the control group are presented in this study. As well as this study was found an increase of patients' hypertension 5 (12.5 %) for Down syndrome patients and 3 (10 %) for the control group. Obesity and being overweight do not appear to significantly increase the risk of cardiometabolic disease. Although ApoA-physiological I's anti-atherosclerotic activities are widely known, ApoA-function II's is still not completely understood. According to certain research, elevated ApoA-II reduces reverse cholesterol transport and HDL's antioxidant capacity, which in turn encourages atherosclerosis. Conclusions: According to the results of the study, TC, TG, and LDL increased significantly while HDL decreased significantly in DS. The results indicated that children with Down syndrome had unfavorable lipid profiles, particularly an increase in Lp (a) levels, as well as a change in the quality of high-density lipoprotein cholesterol, compared to the control group.

Introduction: Nephrotic syndrome (NS) is a disorder characterized by protein leakage in the urine, which can lead to life-threatening hypovolemia, hypercoagulation, and infection. The average age of a kid with NS is four years old, affecting boys more than girls. Nevertheless, the frequency varies by age, gender, race, and geographic area. The frequent use of corticosteroids in these individuals and the recurring nature of the condition might pose substantial health-related obstacles to quality of life. Objective: This paper aims to describe the effects of nephrotic syndrome on children aged 8 to 13 years in Iraq. Patients and Methods: A cross-sectional study was conducted in different hospitals in Iraq, which included 151 cases of pediatric nephrotic syndrome, for both males and females, between the fifth of October 2021 to the nineteenth of January, which were included and divided into two groups, where the first group was Nephrotic Patients (N=85) and the second group was Control Patients ( N=66) where they meet the following requirements: Children between the ages of 8 to 13 years who had nephrotic syndrome for more than one year. It was used in a cross-sectional study of patients with pediatric nephrotic syndrome using the SPSS program. Results and Discussions: In our study, patients with the nephrotic syndrome had low levels according to the scale Ped'SQL (physical, social, educational, and emotional) compared to the healthy controls group the effective Ped'SQL score was surprisingly low. Where a direct statistical relationship was found between the patient group with quality of life with r correlation =+0.876, p-value 0.008, and This explains the role in Table 4. Conclusion: This study reveals that while nephrotic syndrome is treatable, it can hurt patients' physical, emotional, social, and intellectual lives. As a result, this study showed great efficiency and reliability in evaluating the pediatric database in clinical practice, particularly for patients with renal disease. This study showed that Ped'sQL was successful in evaluating all patients, as it discovered that control patients had higher assessment scores than the renal patients' group and that all four sections, which included physical, educational, social, and emotional performance, showed that control patients performed better than nephrotic patients' group.