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39 results on '"Drewitz, Imke"'

26. Long-term single- and multiple-procedure outcome and predictors of success after catheter ablation for persistent atrial fibrillation

Author

Rostock, Thomas, primary, Salukhe, Tushar V., additional, Steven, Daniel, additional, Drewitz, Imke, additional, Hoffmann, Boris A., additional, Bock, Karsten, additional, Servatius, Helge, additional, Müllerleile, Kai, additional, Sultan, Arian, additional, Gosau, Nils, additional, Meinertz, Thomas, additional, Wegscheider, Karl, additional, and Willems, Stephan, additional

Published
2011
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27. Intravenous Administration of Magnesium and Potassium Solution Lowers Energy Levels and Increases Success Rates Electrically Cardioverting Atrial Fibrillation

Author

SULTAN, ARIAN, primary, STEVEN, DANIEL, additional, ROSTOCK, THOMAS, additional, HOFFMANN, BORIS, additional, MÜLLERLEILE, KAI, additional, SERVATIUS, HELGE, additional, DREWITZ, IMKE, additional, LÜKER, JAKOB, additional, MEYER, PHILIP, additional, SALUKHE, TUSHAR, additional, and WILLEMS, STEPHAN, additional

Published
2011
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30. Atrial Fibrillation Cycle Length Is a Sole Independent Predictor of a Substrate for Consecutive Arrhythmias in Patients With Persistent Atrial Fibrillation

Author

Drewitz, Imke, primary, Willems, Stephan, additional, Salukhe, Tushar V., additional, Steven, Daniel, additional, Hoffmann, Boris A., additional, Servatius, Helge, additional, Bock, Karsten, additional, Aydin, Muhammet Ali, additional, Wegscheider, Karl, additional, Meinertz, Thomas, additional, and Rostock, Thomas, additional

Published
2010
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31. Characterization, Mapping, and Catheter Ablation of Recurrent Atrial Tachycardias After Stepwise Ablation of Long-Lasting Persistent Atrial Fibrillation

Author

Rostock, Thomas, primary, Drewitz, Imke, additional, Steven, Daniel, additional, Hoffmann, Boris A., additional, Salukhe, Tushar V., additional, Bock, Karsten, additional, Servatius, Helge, additional, Aydin, Muhammet Ali, additional, Meinertz, Thomas, additional, and Willems, Stephan, additional

Published
2010
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33. Interactive real-time mapping and catheter ablation of the cavotricuspid isthmus guided by magnetic resonance imaging in a porcine model

Author

Hoffmann, Boris A., primary, Koops, Andreas, additional, Rostock, Thomas, additional, Müllerleile, Kai, additional, Steven, Daniel, additional, Karst, Roman, additional, Steinke, Mark U., additional, Drewitz, Imke, additional, Lund, Gunnar, additional, Koops, Susan, additional, Adam, Gerhard, additional, and Willems, Stephan, additional

Published
2009
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34. Chronic Atrial Fibrillation Is a Biatrial Arrhythmia

Author

Rostock, Thomas, primary, Steven, Daniel, additional, Hoffmann, Boris, additional, Servatius, Helge, additional, Drewitz, Imke, additional, Sydow, Karsten, additional, Müllerleile, Kai, additional, Ventura, Rodolfo, additional, Wegscheider, Karl, additional, Meinertz, Thomas, additional, and Willems, Stephan, additional

Published
2008
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35. Atrial Fibrillation Begets Atrial Fibrillation in the Pulmonary Veins On the Impact of Atrial Fibrillation on the Electrophysiological Properties of the Pulmonary Veins in Humans

Author

Rostock, Thomas, Steven, Daniel, Lutomsky, Boris, Servatius, Helge, Drewitz, Imke, Klemm, Hanno, Müllerleile, Kai, Ventura, Rodolfo, Meinertz, Thomas, and Willems, Stephan

Subjects
cardiovascular system
Abstract

ObjectivesOur purpose was to investigate the impact of short-lasting atrial fibrillation (AF) on the electrophysiological properties of the atria and pulmonary veins (PVs) in patients devoid of AF.BackgroundThe presence of AF is associated with electrical remodeling processes that promote a substrate for arrhythmia maintenance in the atria, which has been termed “AF begets AF.” However, it is unclear whether those electrical alterations also occur in the PVs.MethodsThirty-five patients with a left-sided accessory pathway and without a prior history of AF were included. After successful ablation, the effective refractory periods (ERPs) and conduction times of the right atrium (RA), left atrium (LA), and the PVs were determined. Afterwards, AF was induced and maintained for a period of 15 min. Thereafter, the stimulation protocol was repeated.ResultsAt baseline, the PVs had significantly longer ERPs than the atria. After exposure to AF, the ERPs of both the atria and the PVs decreased significantly. The ERPs of the PVs, however, decreased by a significantly greater extent than the ERPs of the atria (PVs: 248 ± 27 ms vs. 211 ± 40 ms, p < 0.001; LA: 233 ± 23 ms vs. 214 ± 20 ms, p = 0.004; RA: 226 ± 29 ms vs. 188 ± 20 ms; p = 0.003). After AF exposure, the PVs demonstrated a significant conduction slowing whereas the atria did not (PVs: 125 ± 33 ms vs. 159 ± 37 ms, p < 0.001; LA: 129 ± 26 ms vs. 130 ± 24 ms, p = NS; RA: 192 ± 36 ms vs. 196 ± 32 ms, p = NS). Finally, AF was more frequently induced after the presence of AF, particularly by pacing in the PVs (14% vs. 49%, p = 0.001).ConclusionsNew-onset, short-lasting AF creates electrical characteristics similar to those of patients with AF. However, these alterations are pronounced in the PVs compared with the atria, indicating that “AF begets AF in the PVs” (Electrophysiological Properties of the Pulmonary Veins; NCT00530608).

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36. [Three-dimensional reconstruction and remote navigation for catheter-guided atrial fibrillation ablation. Does it influence procedural outcomes?].

Author

Steven D, Hoffmann B, Rostock T, Drewitz I, Sultan A, Servatius H, Lüker J, Müllerleile K, and Willems S

Subjects
Atrial Fibrillation diagnostic imaging, Atrial Fibrillation pathology, Catheter Ablation adverse effects, Catheter Ablation instrumentation, Equipment Design, Humans, Magnetics, Radiographic Image Interpretation, Computer-Assisted, Radiography, Interventional instrumentation, Treatment Outcome, Atrial Fibrillation surgery, Catheter Ablation methods, Imaging, Three-Dimensional instrumentation, Magnetic Resonance Imaging, Interventional instrumentation, Radiography, Interventional methods, Robotics instrumentation, Surgery, Computer-Assisted adverse effects, Surgery, Computer-Assisted instrumentation, Tomography, X-Ray Computed instrumentation
Abstract

Catheter ablation of atrial fibrillation has evolved as a widely accepted therapy approach and is now also incorporated in the current guidelines.A major limitation consists of the limited three-dimensional visualization of the complex three-dimensional structures in the left atrium since most procedures have routinely been performed using fluoroscopy alone. Another unsolved problem is the limited durability of lesions sets performed with radiofrequency ablation and therefore somewhat disappointing long-term ablation results besides fluoroscopy exposition for patient and operator as required for safe catheter manipulation.In the recent years we have gained substantial insight with respect to arrhythmia mechanism. At the same time new techniques and developments have become available to improve catheter ablation results.The present article summarizes the available opportunities with respect to three-dimensional mapping including CT/MRI image integration and gives an overview of the robotic and magnetic systems available for catheter ablation.

Published
2011
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37. [Therapy of atrial fibrillation].

Author

Hoffmann BA, Rostock T, Drewitz I, Steven D, and Willems S

Subjects
Algorithms, Anti-Arrhythmia Agents therapeutic use, Anticoagulants therapeutic use, Atrial Fibrillation complications, Atrial Fibrillation diagnosis, Atrial Fibrillation etiology, Catheter Ablation, Chronic Disease, Electric Countershock, Electrocardiography, Humans, Secondary Prevention, Atrial Fibrillation therapy, Stroke prevention & control
Published
2009

38. [Current strategies in the treatment of atrial fibrillation].

Author

Drewitz I, Rostock T, Hoffmann B, Steven D, Servatius H, Meinertz T, and Willems S

Subjects
Anti-Arrhythmia Agents administration & dosage, Anti-Arrhythmia Agents adverse effects, Anticoagulants adverse effects, Atrial Fibrillation diagnosis, Cardiac Pacing, Artificial, Catheter Ablation, Electric Countershock, Electrocardiography, Ambulatory, Flecainide administration & dosage, Flecainide adverse effects, Humans, Male, Middle Aged, Pulmonary Veins surgery, Recurrence, Retreatment, Atrial Fibrillation therapy, Tachycardia, Paroxysmal therapy
Published
2008
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39. [Catheter ablation for atrial fibrillation: clinically established or still an experimental method?].

Author

Willems S, Hoffmann B, Steven D, Drewitz I, Servatius H, Müllerleile K, Meinertz T, and Rostock T

Subjects
Humans, Treatment Outcome, Atrial Fibrillation surgery, Catheter Ablation methods, Catheter Ablation trends, Clinical Trials as Topic trends, Evidence-Based Medicine trends
Abstract

Interventional treatment for atrial fibrillation (AF) has been introduced as a therapeutic option soon after the pulmonary veins (PV) have been discovered as the dominant sources of paroxysmal atrial fibrillation (PAF). Elimination of PV conduction is the initial goal during catheter ablation in this setting. The success rate after the initial procedure varies between 60% and 85%, with > 80% after subsequent interventions. Supported by the current guidelines, interventional treatment of AF is indicated in case of symptomatic arrhythmias refractory to antiarrhythmic treatment. The introduction of the combined, stepwise approach has been another important breakthrough with regard to the treatment of chronic persistent atrial fibrillation (CAF). This strategy includes the combination of all conventional ablation strategies (pulmonary vein isolation [PVI], defragmentation, linear ablation) with the goal of AF termination by radiofrequency current. The first procedure for CAF treatment is quite frequently also only the first step toward stable sinus rhythm with a favorable outcome after AF termination (> 80% sinus rhythm). In more than half of the patients predominantly atrial arrhythmias other than AF have to be targeted in a second procedure. This approach is currently under clinical investigation and so far not "clinically established" due to the fact that it is a quite time-consuming and challenging procedure even in experienced centers. Future studies may help to identify predictors for procedure failure (e.g., left atrial size, AF duration, atrial cycle length) in order to improve patient selection. Additionally, it has to be underscored, that in PAF the relatively high recurrence rate after the first procedure still is the subject of further investigations. This aspect might be improved by the introduction of novel strategies (i.e., testing of concealed PV conduction after ablation with adenosine) or technologies (i.e., robotic navigation) for PAF ablation.

Published
2008
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