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5. CEPA DE TRICHODERMA UTIL PARA EL TRATAMIENTO Y/O PREVENCION DE INFECCIONES PROVOCADAS POR MICROORGANISMOS FITOPATOGENOS

Author

Barroso Albarracin Juan Bautista, Carreras Egana Alfonso, Valderrama Rodriguez Raquel, Chaki Mounira, Begara Morales Juan Carlos, Mercado Blanco Jesus, Perez Artes Encarnacion, Rincon Romero Ana Maria, Carballo Codon Antonio, Benitez Fernandez Tahia, Valverde Corredor Antonio, Felipe Guevara, Rodriguez Palero Maria Jesus, Duenas Sanchez Rafael, Fierro Risco Jesus, and Lopez Garcia Antonio Alejandro

6. CEPA DE TRICHODERMA UTIL PARA EL TRATAMIENTO Y/O PREVENCION DE INFECCIONES PROVOCADAS POR HONGOS PERTENECIENTES AL GENERO VERTICILLIUM

Author

Barroso Albarracin Juan Bautista, Carreras Egana Alfonso, Valderrama Rodriguez Raquel, Chaki Mounira, Begara Morales Juan Carlos, Mercado Blanco Jesus, Perez Artes Encarnacion, Rincon Romero Ana Maria, Carballo Codon Antonio, Benitez Fernandez Tahia, Valverde Corredor Antonio, Felipe Guevara, Rodriguez Palero Maria Jesus, Duenas Sanchez Rafael, Fierro Risco Jesus, and Lopez Garcia Antonio Alejandro

7. Strain of trichoderm useful for the treatment and/or prevention of infections caused by fungi, belonging to the gender verticillium. (Machine-translation by Google Translate, not legally binding)

Author

Barroso Albarracin Juan Bautista, Carreras Egana Alfonso, Valderrama Rodriguez Raquel, Chaki Mounira, Begara Morales Juan Carlos, Mercado Blanco Jesus, Perez Artes Encarnacion, Rincon Romero Ana Maria, Carballo Codon Antonio, Benitez Fernandez Tahia, Valverde Corredor Antonio, Felipe Guevara, Rodriguez Palero Maria Jesus, Duenas Sanchez Rafael, Fierro Risco Jesus, and Lopez Garcia Antonio Alejandro

8. Useful trichoderm cepa for the treatment and/or prevention of infections caused by phytopathogenic microorganisms (Machine-translation by Google Translate, not legally binding)

Author

Barroso Albarracin Juan Bautista, Carreras Egana Alfonso, Valderrama Rodriguez Raquel, Chaki Mounira, Begara Morales Juan Carlos, Mercado Blanco Jesus, Perez Artes Encarnacion, Rincon Romero Ana Maria, Carballo Codon Antonio, Benitez Fernandez Tahia, Valverde Corredor Antonio, Felipe Guevara, Rodriguez Palero Maria Jesus, Duenas Sanchez Rafael, Fierro Risco Jesus, and Lopez Garcia Antonio Alejandro

9. CEPAS DE TRICHODERMA ÚTILES PARA EL TRATAMIENTO Y/O PREVENCIÓN DE INFECCIONES PROVOCADAS POR MICROORGANISMOS FITOPATÓGENOS

Author

Barroso Albarracin Juan Bautista, Carreras Egana Alfonso, Valderrama Rodriguez Raquel, Chaki Mounira, Begara Morales Juan Carlos, Mercado Blanco Jesus, Perez Artes Encarnacion, Rincon Romero Ana Maria, Carballo Codon Antonio, Benitez Fernandez Tahia, Valverde Corredor Antonio, Felipe Guevara, Rodriguez Palero Maria Jesus, Duenas Sanchez Rafael, Fierro Risco Jesus, and Lopez Garcia Antonio Alejandro

10. Temporal and compartment-specific signals coordinate mitotic exit with spindle position

Author

Bahtiyar Kurtulmus, Anton Khmelinskii, Gislene Pereira, Ayse Koca Caydasi, Michael Knop, Rafael Duenas-Sanchez, Çaydaşı, Ayşe Koca (ORCID 0000-0003-2570-1367 & YÖK ID 252978), Khmelinskii, Anton, Duenas-Sanchez, Rafael, Kurtulmus, Bahtiyar, Knop, Michael, Pereira, Gislene, College of Sciences, and Department of Molecular Biology and Genetics

Subjects
0301 basic medicine, Saccharomyces cerevisiae Proteins, Cell division, Checkpoint kinase Kin4, Gtp-binding protein, In-vitro regulation, Budding yeast, Saccharomyces-cerevisiae, Phosphatase Cdc14, Anaphase spindle, Pole bodies, Tem1 Gtpase, Gap complex, Science, Genes, Fungal, Cell, Mitosis, General Physics and Astronomy, Saccharomyces cerevisiae, Spindle Apparatus, Protein Serine-Threonine Kinases, Biology, Article, General Biochemistry, Genetics and Molecular Biology, Chromosome segregation, 03 medical and health sciences, 0302 clinical medicine, Chromosome Segregation, medicine, Guanine Nucleotide Exchange Factors, Compartment (development), Phosphorylation, Anaphase, Multidisciplinary, Kinase, Molecular biology and genetics, General Chemistry, MAP Kinase Kinase Kinases, Cell biology, Cytoskeletal Proteins, 030104 developmental biology, medicine.anatomical_structure, Mitotic exit, 030217 neurology & neurosurgery, Signal Transduction
Abstract

The spatiotemporal control of mitotic exit is crucial for faithful chromosome segregation during mitosis. In budding yeast, the mitotic exit network (MEN) drives cells out of mitosis, whereas the spindle position checkpoint (SPOC) blocks MEN activity when the anaphase spindle is mispositioned. How the SPOC operates at a molecular level remains unclear. Here, we report novel insights into how mitotic signalling pathways orchestrate chromosome segregation in time and space. We establish that the key function of the central SPOC kinase, Kin4, is to counterbalance MEN activation by the cdc fourteen early anaphase release (FEAR) network in the mother cell compartment. Remarkably, Kin4 becomes dispensable for SPOC function in the absence of FEAR. Cells lacking both FEAR and Kin4 show that FEAR contributes to mitotic exit through regulation of the SPOC component Bfa1 and the MEN kinase Cdc15. Furthermore, we uncover controls that specifically promote mitotic exit in the daughter cell compartment., The mitotic exit network (MEN) triggers mitotic exit and can be blocked by the spindle position checkpoint (SPOC). Here the authors show that SPOC kinase Kin4 counterbalances MEN activation by the Cdc fourteen early anaphase release (FEAR) network in the mother cell and that in the absence of FEAR mitotic exit requires daughter cell-confined factors.

Published
2017

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