39 results on '"Duerfeldt, Adam S."'
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2. Design and Assessment of First-Generation Heterobifunctional PPARα/STING Modulators.
3. Guiding the Way: Traditional Medicinal Chemistry Inspiration for Rational Gram-Negative Drug Design
4. Guiding the Way: Traditional Medicinal Chemistry Inspiration for Rational Gram-Negative Drug Design.
5. Design, Synthesis, and Structure–Activity Relationships of Biaryl Anilines as Subtype-Selective PPAR-alpha Agonists
6. The cGAS–STING pathway in diabetic retinopathy and age-related macular degeneration
7. Recent Advances Towards Rational Antibacterial Discovery: Addressing Permeation and Efflux
8. Structure–Uptake Relationship Studies of Oxazolidinones in Gram-Negative ESKAPE Pathogens
9. CpxA Phosphatase Inhibitor Activates CpxRA and Is a Potential Treatment for Uropathogenic Escherichia coli in a Murine Model of Infection
10. Identification of ClpP Dual Isoform Disruption as an Antisporulation Strategy for Clostridioides difficile
11. Loss of ClpP Function in Clostridioides difficile 630 Significantly Impacts Sporulation Systems
12. Small-Molecule Modulation of PPARs for the Treatment of Prevalent Vascular Retinal Diseases
13. First-generation structure-activity relationship studies of 2,3,4,9-tetrahydro-1H-carbazol-1-amines as CpxA phosphatase inhibitors
14. Evolution of a 4-Benzyloxy-benzylamino Chemotype to Provide Efficacious, Potent, and Isoform Selective PPARα Agonists as Leads for Retinal Disorders
15. Structure-guided evolution of a 2-phenyl-4-carboxyquinoline chemotype into PPARα selective agonists: New leads for oculovascular conditions
16. Clostridium difficile ClpP Homologues are Capable of Uncoupled Activity and Exhibit Different Levels of Susceptibility to Acyldepsipeptide Modulation
17. Structure Based Design of a Grp94-Selective Inhibitor: Exploiting a Key Residue in Grp94 To Optimize Paralog-Selective Binding
18. Consequences of Depsipeptide Substitution on the ClpP Activation Activity of Antibacterial Acyldepsipeptides
19. Correction to "Structure–Uptake Relationship Studies of Oxazolidinones in Gram-Negative ESKAPE Pathogens".
20. Clostridium difficile ClpP Homologues are Capable of Uncoupled Activity and Exhibit Different Levels of Susceptibility to Acyldepsipeptide Modulation.
21. Development of Glucose Regulated Protein 94-Selective Inhibitors Based on the BnIm and Radamide Scaffold
22. Grp94 Protein Delivers γ-Aminobutyric Acid Type A (GABAA) Receptors to Hrd1 Protein-mediated Endoplasmic Reticulum-associated Degradation
23. Sclerotiamide: The First Non-Peptide-Based Natural Product Activator of Bacterial Caseinolytic Protease P
24. Author Correction: Property space mapping of Pseudomonas aeruginosa permeability to small molecules.
25. ChemInform Abstract: Cycloadditions of Noncomplementary Substituted 1,2,3‐Triazines.
26. Synthesis and biological evaluation of arylated novobiocin analogs as Hsp90 inhibitors
27. Hsp90 inhibition: Elimination of shock and stress
28. Cycloadditions of Noncomplementary Substituted 1,2,3-Triazines
29. ChemInform Abstract: Total Syntheses of (-)-Pyrimidoblamic Acid and P-3A.
30. Total Syntheses of (−)-Pyrimidoblamic Acid and P-3A
31. Design, synthesis, and biological activity of bicyclic radester analogues as Hsp90 inhibitors
32. A Fundamental Relationship between Hydrophobic Properties and Biological Activity for the Duocarmycin Class of DNA-Alkylating Antitumor Drugs: Hydrophobic-Binding-Driven Bonding
33. Glucose-regulated Protein 94 Triage of Mutant Myocilin through Endoplasmic Reticulum-associated Degradation Subverts a More Efficient Autophagic Clearance Mechanism
34. Development of a Grp94 inhibitor
35. Design, Synthesis, and Biological Evaluation of Conformationally Constrained cis-Amide Hsp90 Inhibitors
36. Hydrating for Resistance to Radicicol
37. A FundamentalRelationship between Hydrophobic Propertiesand Biological Activity for the Duocarmycin Class of DNA-AlkylatingAntitumor Drugs: Hydrophobic-Binding-Driven Bonding.
38. Grp94 Protein Delivers γ-Aminobutyric Acid Type A (GABAA) Receptors to Hrd1 Protein-mediated Endoplasmic Reticulum associated Degradation.
39. Total syntheses of (-)-pyrimidoblamic acid and P-3A.
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