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1. Cutaneous mastocytosis in a child with xeroderma pigmentosum: A case report.

Author

Baklan, E., Duman, N., Akalın, T., and Karaarslan, I.

Subjects
*MAST cell disease, *XERODERMA pigmentosum, *MAST cells, *SKIN biopsy, *RARE diseases, *PHOTOSENSITIVITY
Abstract

Xeroderma pigmentosum is a rare autosomal recessive inherited skin disorder characterized by severe photosensitivity, changes in skin pigmentation, development of malignant tumors at an early age, and sometimes progressive neurological degeneration. Mastocytosis is a rare disease characterized by the increase and accumulation of clonal mast cells in various organs. A two-year-old boy with xeroderma pigmentosum presented with light brown papular lesions, which following skin biopsy were diagnosed as mastocytosis. As far as we know, there is only one adult case in the literature in which xeroderma pigmentosum and mastocytosis occur in the same subject. The current work concerns the coexistence, which has never been previously reported in the literature, of mastocytosis and xeroderma pigmentosum in a child. [ABSTRACT FROM AUTHOR]

Published
2024

2. Can anterolateral thigh flap be a rescuer in lower extremity injuries?

Author

ATILGAN, N., IPEK, B., DUMAN, N., ORHAN, O., and YILMAZ, M.

Abstract

OBJECTIVE: The lower extremity contains a variety of functional structures therefore re-establishing soft tissue coverage in large-scale injuries is a challenging procedure. Microsurgery has made progress in reducing donor morbidity and achieving a functional and aesthetic appearance in recent years. This study aimed to apply anterolateral thigh (ALT) flap to tissue defects in the lower extremity and to discuss the results. PATIENTS AND METHODS: Twenty-three patients who were admitted to our hospital with lower extremity trauma and underwent ALT flap surgery due to soft tissue defect between November 2020 and March 2022 were included in the study. Patients' demographic data, the applied surgical procedure, the development of postoperative complications, and postoperative functional results were evaluated. RESULTS: Twenty-three patients were included in this research. The mean age of the patients was 36.56±14.67 (10-61). Of these patients, 3 were female (13%), and 20 were male (87%). The most common etiology was traffic accident (n=8, 34%), followed by gunshot injuries (n=5, 21%), electrical burn (n=4, 17%), open fractures (n=2, 7%), infection (n=2, 7%), diabetic foot (n=1, 4%), skin tumor (n=1, 4%). Flaps were raised from the contralateral extremity in twelve patients (52%) and on the ipsilateral extremity in eleven patients (48%). The average time from first trauma to free flap surgery was 10.7±5 days (4-22). The average postoperative hospitalization was 13.6 days (9-23 days). The average follow-up time of patients was 8 months (3-13 months). The donor site is closed with primary saturation in 19 patients (82%) and closed with split-thickness skin grafting in 4 patients (18%). Our overall success rate was 96%. We had only one total flap failure out of twenty-three patients (4%). CONCLUSIONS: ALT-free flap is an excellent choice for reconstructing lower extremity complex defects. For experienced surgeons, the ALT flap can be used successfully in the treatment of soft tissue defects of variable size in the lower extremity. [ABSTRACT FROM AUTHOR]

Published
2023

4. Comparison of the results of percutaneous and open screw fixation in the treatment of scaphoid nonunion fractures.

Author

ATILGAN, N., DUMAN, N., COLAK, T.S., KORUCU, I.H., DEMIRYUREK, M., and YILMAZ, M.

Abstract

OBJECTIVE: Our study aims to compare the clinical results of percutaneous screw fixation and non-vascularized bone grafting with open screw fixation in patients who did not achieve union due to failure in diagnosis and treatment after a scaphoid fracture. PATIENTS AND METHODS: Forty-three patients with scaphoid nonunion fractures corresponding to the first three Slade and Dodds classification were divided into two groups. Non-vascularized bone grafting with open reduction and internal fixation (ORIF) was applied to 24 patients in the first group, and 19 patients in the second group were treated with a closed reduction and internal fixation (CRIF) (percutaneous screw fixation). The patients were followed up for preoperative and postoperative functional scores and time to union. RESULTS: Our study found that the scaphoid was most commonly fractured in the waist of the scaphoid. In our study, we found that distal scaphoid fractures had the highest union rate (100%), followed by the waist fractures (93.2%) and the weakest union (50%) in the proximal pole fractures. We observed that the fastest union had occurred in the fractures of the waist. We also observed that the union was completed earlier in patients who operated with ORIF than those with CRIF. We found union in 87.5% of patients who underwent ORIF, in 84.2% of patients who underwent CRIF. CRIF operation duration was shorter than expected from ORIF operation duration. CONCLUSIONS: We found that similar union rates could be achieved in the patient groups who underwent percutaneous and open screw fixation by selecting the appropriate patient in scaphoid nonunion fractures. Union was faster and functional results were more satisfactory in the ORIF group. The operation time was shorter in the CRIF group. [ABSTRACT FROM AUTHOR]

Published
2022

5. Multidisciplinary treatment and functional outcome evaluation of combined injuries of nerves, vessels, and flexor tendons: spaghetti wrist.

Author

ATILGAN, N., DUMAN, N., COLAK, T. S., KORUCU, I. H., and DEMIRYUREK, M.

Abstract

OBJECTIVE: In this study, we aimed to evaluate the effectiveness of the modified Kessler technique in managing spaghetti wrist lacerations by multidisciplinary treatment. PATIENTS AND METHODS: Patients who were operated and followed up with the diagnosis of spaghetti wrist tears in our clinic between January 2012 and December 2020 were included in the study. In the postoperative follow-ups, the parameters evaluating the functionality of the patients were examined. RESULTS: Patients were 105 male (86.7%) and 16 women (13.2%), with a mean age of 36.83 ± 16.38 years. At the final follow-up, functional outcomes were assessed. The most common injury mechanism was glass-related injuries (35.5%). The mean starting surgery time of the patients was 4.64±2.98 hours. The most frequently involved structures were the palmaris longus with a rate of 51% and the flexor digitorum superficialis with a rate of 45%. There were significant differences regarding intrinsic function and grip strength between male and female patients (p = 0.04, p = 0.21, respectively). There were significant differences regarding sensation and grip strength between smoker and nonsmoker patients (p = 0.03, p = 0.01, respectively). The number of the damaged structures was negatively correlated with postsurgical functional outcomes of four tests, including tendon function, opposition, intrinsic function, and grip strength. The physical therapy period was correlated to hand function tests (r = 0.756, p < 0.05). Nerve damage was negatively correlated with sensation (p = 0.011, r = -0.932). CONCLUSIONS: The modified Kessler technique is reliable with functional outcomes for spaghetti wrist injuries involving tendons, nerves, and arteries. Meticulous and early surgical treatment within the first 8 hours of spaghetti wrist injury and early initiation and long-term physical therapy are vital in patients’ functional outcomes. [ABSTRACT FROM AUTHOR]

Published
2022

7. Topiramate and darbepoetin alpha ameliorate bilirubin-induced neurons cell damage

Author

Duman, N., Ozbal, SEDA, Yucesoy, E., Tuzun, FUNDA, Kumral, A., Yilmaz, O., Ergur, B. U., Sonmez, A., Olgun, YÜKSEL, Kirkim, GÜNAY, Evin, H., Ozkan, H., and Baysal, B.

Abstract

OBJECTIVE: The aim of this study was to determine whether prophylactic darbepoetin alpha and/or topiramate administration could prevent bilirubin neurotoxicity (BNTx) in experimental model of kernicterus.

Published
2021

9. P121 The effect of training about nebuliser cleaning and disinfection on the knowledge levels and practises of the caregivers of patients with cystic fibrosis

Author

Cenk, M., primary, Ergenekon, A.P., additional, Yilmaz Yegit, C., additional, Guliyeva, A., additional, Kalyoncuoglu, M., additional, Gokdemir, Y., additional, Erdem Eralp, E., additional, Mursaloglu, H., additional, Tastan, G., additional, Uzunoglu, B., additional, Duman, N., additional, Karahasan, A., additional, Karakoc, F., additional, and Karadag, B., additional

Published
2021
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12. SAT-410 Clinicopathologic Features and Outcomes of Patients with Crescentic Glomerulonephritis with Renal Involvement: A Single-Center, 13-year Retrospective Study from Turkey

Author

ERDOGMUS, S., primary, Eren Sadioglu, R., additional, Kumru, G., additional, Eyupoglu, S., additional, Kutlay, S., additional, Keven, K., additional, Nergizoglu, G., additional, Ates, K., additional, Erturk, S., additional, Duman, N., additional, and Sengul, S., additional

Published
2020
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13. A CASE WITH DUPLICATION 2q: A77

Author

Toksoy, G, Türköver, B, Şahin, Laleli E, Şensoy, Yeşil G, Sayar, C, Duman, N, Şimşek, E, Deniz, E, and Tükün, A

Published
2010

26. Topiramate and darbepoetin alpha ameliorate bilirubin-induced neuronal cell damage.

Author

BAYSAL, B., TUZUN, F., YUCESOY, E., OZBAL, S., ERGUR, B. U., SONMEZ, A., OLGUN, Y., KIRKIM, G., EVIN, H., DUMAN, N., KUMRAL, A., YILMAZ, O., and OZKAN, H.

Abstract

OBJECTIVE: The aim of this study was to determine whether prophylactic darbepoetin alpha and/or topiramate administration could prevent bilirubin neurotoxicity (BNTx) in experimental model of kernicterus. MATERIALS AND METHODS: A total of 60 Wistar albino rat puppies with experimental kernicterus model were included in the study. The Kernicterus was established administering a bilirubin injection via a cisterna magna puncture 30 minutes after ip drug injection. The puppies were divided into five groups with 12 in each group as shown below: a control group, bilirubin group, darbepoetin alpha group, topiramate group and darbepoetin alpha+ topiramate group. Darbepoetin alpha and/or topiramate were administered on day 5 intraperitoneally (ip). At the 6th and 24th hours, bilirubin induced neurological dysfunction (BIND) score was used to assess behavioral changes. Hearing functions were evaluated on days 10 and 28. On day 30, the Water Maze water tank test was implemented to evaluate spatial memory. The rats were sacrificed on days 6 and 34 and apoptosis in the globus pallidus and hippocampus was examined. RESULTS: The BIND score was improved following darbepoetin alpha treatment. Neither darbepoetin alpha nor topiramate therapy ameliorate spatial memory. There were no significant differences between groups in terms of the auditory brainstem response (ABR). The combined use of darbepoetin alpha and topiramate lead to slight decrease in apoptosis. CONCLUSIONS: Darbepoetin alpha or topiramate administration ameliorates bilirubin induced neurological dysfunction in experimental model of kernicterus. [ABSTRACT FROM AUTHOR]

Published
2021

28. Outcome of the Respiratory Syncytial Virus related acute lower respiratory tract infection among hospitalized newborns: a prospective multicenter study

Author

Kiray Bas, E., Koc, E., Hirfanoglu, I.M., Celik, U., Yalaz, M., Ergor, S.N., Duman, N., Iscan, B., Unal, S., Cakir, B., Ertugrul, S., Satar, M., Ozlu, F., Cevit, O., Bolat, F., Bilgili, G., Yigit, Y., Kurt, A., Tekgunduz, K.S., Caner, I., Yildiz, D., Kahvecioglu, D., Oygur, N., Erdogan, Y., Turkmen, M.K., Anik, A., Arsan, Saadet, Atasay, Begum, Ates, Can, Gokmen, Zeynel, Tunc, Turan, Akcakus, Mustafa, Zenciroglu, Aysegul, Akduman, Hasan, Cakir, Ufuk, ERDEVE, ÖMER, Alan, Serdar, Melekoglu, N.A., Celik, I., Korkmaz, A., Ozdemir, R., Karadag, A., Ozer, E., Ilhan, O., Mutlu, M., Aslan, Y., Erener- Ercan, T., Cetinkaya, M., Sahin, O., Akin, M.A., Okumus, N., Demirel, G., Kilic, A., Turkoglu-Unal, E., Bulbul, A., Takci, S., Anuk-Ince, D., Ciftdemir, N.A., Acunas, B., Ozkan, H., Koksal, N., Okulu, E., Demir, N., Tuncer, O., Dizdar, E.A., Oguz, S., Dilmen, U., Bozkaya, D., Sivasli, E., Alan, S., Neonatal Intensive Care Unit, Hitit University Corum Training and Research Hospital, Vedat Dolakay Cad. No: 90A/16 Gaziosmanpasa, Ankara, 06100, Turkey -- Erdeve, O., Division of Neonatology, Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey -- Cakir, U., Division of Neonatology, Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey -- Akduman, H., Division of Neonatology, Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey -- Zenciroglu, A., Neonatal Intensive Care Unit, Dr Sami Ulus Maternity and Children Training and Research Hospital, Ankara, Turkey -- Akcakus, M., Division of Neonatology, Department of Pediatrics, Akdeniz University Medical School, Antalya, Turkey -- Tunc, T., Division of Neonatology, Department of Pediatrics, Gulhane Military School of Medicine, Ankara, Turkey -- Gokmen, Z., Neonatal Intensive Care Unit, Konya Training and Research Hospital, Konya, Turkey -- Ates, C., Department of Biostatistics, Ankara University School of Medicine, Ankara, Turkey -- Atasay, B., Division of Neonatology, Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey -- Arsan, S., Division of Neonatology, Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey -- Anik, A., Adnan Menderes University, Faculty of Medicine, Aydin, Turkey -- Turkmen, M.K., Adnan Menderes University, Faculty of Medicine, Aydin, Turkey -- Erdogan, Y., Akdeniz University, Medical School, Antalya, Turkey -- Oygur, N., Akdeniz University, Medical School, Antalya, Turkey -- Kahvecioglu, D., Ankara University, School of Medicine, Ankara, Turkey -- Yildiz, D., Ankara University, School of Medicine, Ankara, Turkey -- Caner, I., Ataturk University, Faculty of Medicine, Erzurum, Turkey -- Tekgunduz, K.S., Ataturk University, Faculty of Medicine, Erzurum, Turkey -- Kurt, A., Balikesir Ataturk Government Hospital, Balikesir, Turkey -- Yigit, Y., Celal Bayar University, Faculty of Medicine, Manisa, Turkey -- Bilgili, G., Celal Bayar University, Faculty of Medicine, Manisa, Turkey -- Bolat, F., Cumhuriyet University, Faculty of Medicine, Sivas, Turkey -- Cevit, O., Cumhuriyet University, Faculty of Medicine, Sivas, Turkey -- Ozlu, F., Cukurova University, Faculty of Medicine, Adana, Turkey -- Satar, M., Cukurova University, Faculty of Medicine, Adana, Turkey -- Ertugrul, S., Dicle University, Faculty of Medicine, Diyarbakir, Turkey -- Cakir, B., Ankara Children's Health Hematology Oncology Research Hospital, Ankara, Turkey -- Unal, S., Ankara Children's Health Hematology Oncology Research Hospital, Ankara, Turkey -- Iscan, B., Dokuz Eylul University, School of Medicine, Izmir, Turkey -- Duman, N., Dokuz Eylul University, School of Medicine, Izmir, Turkey -- Ergor, S.N., Ege University, Faculty of Medicine, Izmir, Turkey -- Yalaz, M., Ege University, Faculty of Medicine, Izmir, Turkey -- Celik, I., Etlik Zübeyde Hanim Women's Health Teaching and Research Hospital, Ankara, Turkey -- Celik, U., Etlik Zübeyde Hanim Women's Health Teaching and Research Hospital, Ankara, Turkey -- Hirfanoglu, I.M., Gazi University, Faculty of Medicine, Ankara, Turkey -- Koc, E., Gazi University, Faculty of Medicine, Ankara, Turkey -- Sivasli, E., Gaziantep University, Faculty of Medicine, Gaziantep, Turkey -- Melekoglu, N.A., Gaziantep University, Faculty of Medicine, Gaziantep, Turkey -- Kiray Bas, E., Gaziantep Children's Hospital, Gaziantep, Turkey -- Bozkaya, D., Hacettepe University, Faculty of Medicine, Ankara, Turkey -- Korkmaz, A., Hacettepe University, Faculty of Medicine, Ankara, Turkey -- Ozdemir, R., Inönü University, Faculty of Medicine, Malatya, Turkey -- Karadag, A., Inönü University, Faculty of Medicine, Malatya, Turkey -- Ozer, E., Tepecik Training and Research Hospital, Izmir, Turkey -- Ilhan, O., Tepecik Training and Research Hospital, Izmir, Turkey -- Mutlu, M., Karadeniz Technical University, Faculty of Medicine, Trabzon, Turkey -- Aslan, Y., Karadeniz Technical University, Faculty of Medicine, Trabzon, Turkey -- Erener- Ercan, T., Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Turkey -- Cetinkaya, M., Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Turkey -- Sahin, O., Kayseri Training and Research Hospital, Kayseri, Turkey -- Akin, M.A., Kayseri Training and Research Hospital, Kayseri, Turkey -- Okumus, N., Dr. Sami Ulus Maternity and Children Training and Research Hospital, Ankara, Turkey -- Demirel, G., Samsun Maternal and Child Health Hospital, Samsun, Turkey -- Kilic, A., Samsun Maternal and Child Health Hospital, Samsun, Turkey -- Turkoglu-Unal, E., Sisli Hamidiye Etfal Children Hospital, Istanbul, Turkey -- Bulbul, A., Sisli Hamidiye Etfal Children Hospital, Istanbul, Turkey -- Takci, S., Gaziosmanpasa University, Faculty of Medicine, Tokat, Turkey -- Anuk-Ince, D., Gaziosmanpasa University, Faculty of Medicine, Tokat, Turkey -- Ciftdemir, N.A., Trakya University, School of Medicine, Edirne, Turkey -- Acunas, B., Trakya University, School of Medicine, Edirne, Turkey -- Ozkan, H., Uludag University, Faculty of Medicine, Bursa, Turkey -- Koksal, N., Uludag University, Faculty of Medicine, Bursa, Turkey -- Okulu, E., Van Training and Research Hospital, Van, Turkey -- Demir, N., Yuzuncu Yil University, School of Medicine, Van, Turkey -- Tuncer, O., Yuzuncu Yil University, School of Medicine, Van, Turkey -- Dizdar, E.A., Zekai Tahir Burak Maternity Teaching Hospital, Ankara, Turkey -- Oguz, S., Zekai Tahir Burak Maternity Teaching Hospital, Ankara, Turkey -- Dilmen, U., Zekai Tahir Burak Maternity Teaching Hospital, Ankara, Turkey, Hitit Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Alan, S, Erdeve, O, Cakir, U, Akduman, H, Zenciroglu, A, Akcakus, M, Tunc, T, Gokmen, Z, Ates, C, Atasay, B, Arsan, S, Sakarya Üniversitesi/Tıp Fakültesi/Dahili Tıp Bilimleri Bölümü, Caner, İbrahim, and Çukurova Üniversitesi

Subjects
Male, Pediatrics, Neonatal intensive care unit, Turkey, viruses, health care facilities, manpower, and services, respiratory syncytial virus, Infant, Newborn, Diseases, Disease Outbreaks, 0302 clinical medicine, newborn, Medicine, 030212 general & internal medicine, Prospective Studies, Neonatal Intensive Care Unit, Respiratory system, Prospective cohort study, Respiratory Tract Infections, Cross Infection, Respiratory tract infections, Incidence (epidemiology), Obstetrics and Gynecology, Obstetrics & Gynecology, Prognosis, Respiratory Syncytial Viruses, Hospitalization, Treatment Outcome, Female, medicine.drug, Palivizumab, medicine.medical_specialty, education, Respiratory Syncytial Virus Infections, Antiviral Agents, 03 medical and health sciences, 030225 pediatrics, Intensive care, Intensive Care Units, Neonatal, Humans, outbreak, business.industry, Infant, Newborn, Outbreak, Infant, nosocomial, Newborn, Pediatrics, Perinatology and Child Health, Respiratory Syncytial Virus, Nosocomial, business
Abstract

Taylor and Francis Ltd, Aim: To determine the incidence and outcomes of respiratory syncytial virus (RSV)-related acute lower respiratory tract infection (ALRI) including morbidity, nosocomial infection and mortality among newborn infants who were admitted to the neonatal intensive care units (NICUs).Methods: A multicenter, prospective study was conducted in newborns who were hospitalized with community acquired or nosocomial RSV infection in 44 NICUs throughout Turkey. Newborns with ALRI were screened for RSV infection by Respi-Strip®-test. Main outcome measures were the incidence of RSV-associated admissions in the NICUs and morbidity, mortality and epidemics results related to these admissions.Findings: The incidence of RSV infection was 1.24% (n: 250) and RSV infection constituted 19.6% of all ALRI hospitalizations, 226 newborns (90.4%) had community-acquired whereas 24 (9.6%) patients had nosocomial RSV infection in the NICUs. Of the 250 newborns, 171 (68.4%) were full-term infants, 183 (73.2%) had a BW >2500 g. RSV-related mortality rate was 1.2%. Four NICUs reported seven outbreaks on different months, which could be eliminated by palivizumab prophylaxis in one NICU.Conclusion: RSV-associated ALRI both in preterm and term infants accounts an important percent of hospitalizations in the season, and may threat other high-risk patients in the NICU. © 2015 Taylor & Francis., Alan, S.; Neonatal Intensive Care Unit, Hitit University Corum Training and Research Hospital, Vedat Dolakay Cad. No: 90A/16 Gaziosmanpasa, Turkey; email: alanserdar@gmail.com

Published
2016

30. Incidence and severity of retinopathy of prematurity in Turkey

Author

Bas, A.Y., Koc, E., Dilmen, U., Oguz, S.S., Ovali, F., Demirel, N., Zenciroglu, A., Tekin, N., Caner, I., Arslanoglu, S., Celik, Y., Öztürk, A., Cömert, S., Bulbul, A., Kultursay, N., Koklu, E., Duman, N., Koksal, N., Salihoglu, O., Coban, A., Demirel, G., Bolat, F., Gökalp, A., Satar, M., Ipek, M.S., Bas, E.K., Narli, N., Mutlu, M., Cetinkaya, M., Akman, I., Yigit, S., Narter, F., Sivasli, E., Ahrabi, A.F., Atalay, Y., Tanyeri, B., Arsan, S., Perk, Y., Ors, R., Tuncer, O., Ecevit, A., Oygur, N., Özdemir, Özmert Muhammet Ali, Hakan, N., Aliefendioglu, D., Acunas, B., Cetin, H., Ozek, E., Tunc, T., Turkmen, M., Aydemir, C., Takci, S., and Bas, A.Y., Department of Neonatology, Etlik Zubeyde Hanim Women's Health Teaching and Research Hospital, Etlik, Keciören, Ankara, 06010, Turkey -- Koc, E., Department of Neonatology, Gazi University, Faculty of Medicine, Ankara, Turkey -- Dilmen, U., Department of Neonatology, Dr. Zekai Tahir Burak Women's Health Education and Research Hospital, Ankara, Turkey -- Oguz, S.S., Department of Neonatology, Dr. Zekai Tahir Burak Women's Health Education and Research Hospital, Ankara, Turkey -- Ovali, F., Zeynep Kamil Maternity and Children's Education and Training Hospital, Istanbul, Turkey -- Demirel, N., Department of Neonatology, Etlik Zubeyde Hanim Women's Health Teaching and Research Hospital, Etlik, Keciören, Ankara, 06010, Turkey -- Zenciroglu, A., Dr Sami Ulus Maternity and Children's Hospital, Ankara, Turkey -- Tekin, N., Osmangazi University Faculty of Medicine, Eskisehir, Turkey -- Caner, I., Ataturk University Faculty of Medicine, Erzurum, Turkey -- Arslanoglu, S., Dr Behcet Uz Children's Hospital, Izmir, Turkey -- Celik, Y., Mersin University Faculty of Medicine, Mersin, Turkey -- Öztürk, A., Erciyes University Faculty of Medicine, Kayseri, Turkey -- Cömert, S., Suleymaniye Maternity, Research and Training Hospital, Istanbul, Turkey -- Bulbul, A., Sisli Hamidiye Etfal Education and Research Hospital, Istanbul, Turkey -- Kultursay, N., Ege University Faculty of Medicine, Izmir, Turkey -- Koklu, E., Megapark Hospital, Kahramanmaras, Turkey -- Duman, N., Dokuz Eylul University Faculty of Medicine, Izmir, Turkey -- Koksal, N., Uludag University Faculty of Medicine, Bursa, Turkey -- Salihoglu, O., Bakirkoy Dr Sadi Konuk Training and Research Hospital, Istanbul, Turkey -- Coban, A., Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey -- Demirel, G., Samsun Maternal and Child Health Hospital, Samsun, Turkey -- Bolat, F., Cumhuriyet University Faculty of Medicine, Sivas, Turkey -- Gökalp, A., Kocaeli University Faculty of Medicine, Kocaeli, Turkey -- Satar, M., Cukurova University Faculty of Medicine, Adana, Turkey -- Ipek, M.S., Diyarbakir Maternal and Child Health Hospital, Diyarbakir, Turkey -- Bas, E.K., Gaziantep Children's Hospital, Gaziantep, Turkey -- Narli, N., Metro Hospital, Adana, Turkey -- Mutlu, M., Karadeniz Technical University Faculty of Medicine, Trabzon, Turkey -- Cetinkaya, M., Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Turkey -- Akman, I., Bahcesehir University Faculty of Medicine, Goztepe Medical Park Hospital, Istanbul, Turkey -- Yigit, S., Hacettepe University Faculty of Medicine, Ankara, Turkey -- Narter, F., Lutfi Kirdar Kartal Education and Research Hospital, Istanbul, Turkey -- Sivasli, E., Gaziantep University Faculty of Medicine, Gaziantep, Turkey -- Ahrabi, A.F., Eskisehir State Hospital, Eskisehir, Turkey -- Atalay, Y., Department of Neonatology, Gazi University, Faculty of Medicine, Ankara, Turkey -- Tanyeri, B., Bezmialem University Faculty of Medicine, Istanbul, Turkey -- Arsan, S., Ankara University Faculty of Medicine, Ankara, Turkey -- Perk, Y., Istanbul University, Cerrahpasa Faculty of Medicine, Istanbul, Turkey -- Ors, R., Necmettin Erbakan University, Meram Faculty of Medicine, Konya, Turkey -- Tuncer, O., Yuzuncu Yil University Faculty of Medicine, Van, Turkey -- Ecevit, A., Baskent University Faculty of Medicine, Ankara, Turkey -- Oygur, N., Akdeniz University Faculty of Medicine, Antalya, Turkey -- Ozdemir, O.M., Pamukkale University Faculty of Medicine, Denizli, Turkey -- Hakan, N., Erzurum Training and Research Hospital, Erzurum, Turkey -- Aliefendioglu, D., Kirikkale University Faculty of Medicine, Kirikkale, Turkey -- Acunas, B., Trakya University Faculty of Medicine, Edirne, Turkey -- Cetin, H., Suleyman Demirel University Faculty of Medicine, Isparta, Turkey -- Ozek, E., Marmara University Faculty of Medicine, Istanbul, Turkey -- Tunc, T., Gulhane Military Medical Academy, Ankara, Turkey -- Turkmen, M., Adnan Menderes University Faculty of Medicine, Aydin, Turkey -- Aydemir, C., Bulent Ecevit University Faculty of Medicine, Zonguldak, Turkey -- Takci, S., Gaziosmanpasa University Faculty of Medicine, Tokat, Turkey

Subjects
Male, congenital, hereditary, and neonatal diseases and abnormalities, genetic structures, Turkey, retrospective study, prevalence, Gestational Age, Review, Infant, Premature, Diseases, Severity of Illness Index, Turkey (republic), Neonatal Screening, newborn, Risk Factors, Humans, controlled study, Retinopathy of Prematurity, human, procedures, Retrospective Studies, newborn screening, Incidence, prematurity, Infant, Newborn, birth weight, clinical trial, low level laser therapy, infant, major clinical study, eye diseases, female, multicenter study, priority journal, risk factor, retrolental fibroplasia, disease severity, sense organs, newborn intensive care, Infant, Premature
Abstract

BMJ Publishing Group, Background: The purpose of this study was to estimate the current incidence of retinopathy of prematurity (ROP) and the need for treatment in preterm infants in Turkey. Methods: The study included preterm infants who had been screened for ROP between 2011 and 2013 in 49 neonatal intensive care units. Infants with birth weight (BW) ?1500 g or ?32 weeks' gestational age and those with BW >1500 g or >32 weeks' GA with an unstable clinical course were included. The incidence of any ROP or severe ROP and treatment modalities were determined. Results: The study population included 15 745 preterm infants: 11 803 (75%) with GA ?32 weeks, and 3942 (25%) with GA >32 weeks. Overall, 30% were found to have any stage of ROP, and 5% had severe ROP. Severe ROP was diagnosed in 8.2% of infants with BW ?1500 g and 0.6% of infants with BW >1500 g. Of all infants diagnosed with ROP, 16.5% needed laser photocoagulation, and 20 patients born at >32 weeks' GA required this treatment modality. Vitroretinal surgery was performed in 28 infants with severe ROP: 23 with GA ?28 weeks and 5 with GA 29-32 weeks. Conclusions: The findings of our study have the important implication that more mature babies are at risk of severe ROP requiring treatment. An effective programme for detecting and treating ROP should be established in Turkey., Bas, A.Y.; Department of Neonatology, Etlik Zubeyde Hanim Women's Health Teaching and Research HospitalTurkey

Published
2015

33. Phocomelia, ectrodactyly, skull defect and urinary system anomaly: Schinzel-phocomelia syndrome?

Author

Nihat Satar, Temoçin Ak, Nurdan Evliyaoğlu, Süleymanova D, Derya Ufuk Altintas, Duman N, and Çukurova Üniversitesi

Subjects
Ectrodactyly, Ectromelia, Urinary system, Schinzel phocomelia syndrome, Urinary system anomaly, Skull defect, Phocomelia, Fingers, Sacral hypoplasia, Genetics, medicine, Humans, Abnormalities, Multiple, Urinary Tract, Genetics (clinical), business.industry, Skull, Infant, Newborn, Urography, Syndrome, Anatomy, medicine.disease, Sacrum, Hypoplasia, Schinzel-phocomelia syndrome, medicine.anatomical_structure, Arm, Upper limb, Female, business
Abstract

PubMedID: 8740915 This report describes a girl with phocomelia of the right upper limb, ectrodactyly, sacral hypoplasia and a large skull defect, but with normal growth and mental development. Ultrasonography and intravenous pyelography showed bilateral hydronephrosis and dilated ureters. We conclude that this patient may represent Schinzel-phocomelia syndrome with additional urinary tract anomalies.

Published
2008
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34. Natal Diş

Author

KILINÇ, G., KILINÇ, Gülser, ARSLAN, M. Koyuncu, KOYUNCU ARSLAN, Meltem, DUMAN, N., and DUMAN, Nuray

Subjects
Yeni doğan,natal diş,mandibular kesici dişler, stomatognathic diseases, stomatognathic system, Newborn,natal teeth,mandibular inciso
Abstract

Natal teeth are defined as teeth that are present in the mouth at the birth, and the occurrence is rare. Natal teeth may be uncomfortable for a nursing mother and present a risk of aspiration and swallowing by the infant if they are loose. Besides they may cause irritation and trauma to the infant's soft tissues. In this article a female infant with two natal teeth is presented. The teeth were present in the mandibular incisor region and were excessively mobile and cause discomfort for the nursing mother. They were extracted because of the fear of aspiration, Natal dişler doğumda ağızda görülen dişler olarak tanımlanır ve nadir olarak görülürler. Emzirme esnasında annesdişlerden rahatsızlık duyabilir, ayrıca dişlerin lükse olması nedeniyle emme sırasında bebeğin dişleri aspire etmesi riski oluşabilir. Bu dişler bebeğin ağız yumuşak dokularında irritasyon ve travmaya neden olabilirler. Bu olguda iki natal dişli doğan kız bebek sunulmuştur. Olguda natal dişler mandibulada alt ön kesici dişler bölgesinde bulunmaktaydı ve dişlerin lükse olması nedeniyle emzirme güçlüğü saptandı. Bebeğin dişlerini aspire edebileceği düşüncesiyle dişlerin çekimi yapıldı

Published
2015

35. DISTRIBUTION AND DIVERSITY OF CYST NEMATODE (NEMATODA: HETERODERIDAE) POPULATIONS IN THE REPUBLIC OF AZERBAIJAN, AND THEIR MOLECULAR CHARACTERIZATION USING ITS-RDNA ANALYSIS.

Author

Dababat, A. A., Muminjanov, H., Erginbas-Orakci, G., Fakhraddin, G. Ahmadova, Waeyenberge, L., Yildiz, Ş., Duman, N., and Imren, M.

Subjects
NEMATODES, CYST nematodes, CROP rotation, AGRICULTURAL industries, HETERODERA, POPULATION
Abstract

Copyright of Nematropica is the property of Organization of Nematologists of Tropical America and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2019

39. Inhibition of vascular endothelial growth factor-induced retinal neovascularization by retinoic acid in experimental retinopathy of prematurity

Author

Hasan Ozkan, Duman N, Kumral A, Kasap B, Ea, Ozer, Lebe B, Yaman A, Berk T, Yilmaz O, and Ozer E

Subjects
Vascular Endothelial Growth Factor A, genetic structures, Physiology, Infant, Newborn, Tretinoin, General Medicine, Retinal Neovascularization, Retina, eye diseases, Rats, Disease Models, Animal, Animals, Newborn, Animals, Humans, Retinopathy of Prematurity, sense organs, Rats, Wistar
Abstract

Vascular endothelial growth factor (VEGF) has an important role in the pathogenesis of retinopathy of prematurity (ROP) and inhibition of VEGF expression in the neovascular phase might prevent destructive neovascularization in ROP. It is suggested that retinoids exert a highly potent antiangiogenic activity by inhibiting VEGF expression. The aim of this study was to demonstrate the preventive effect of retinoic acid (RA) on the VEGF-induced retinal neovascularization in a rat model of ROP. Wistar albino rats were placed into incubators at birth and exposed to an atmosphere alternating between 50 % and 10 % O(2) every 24 hours. After 14 days, the animals were removed to room air and received either an intraperitoneal injection of RA (5 mg/kg/day) (n=9) or saline (n=4) daily for six days, and sacrificed at 21 days. Other rats (n=4) were raised in room air and served as age-matched controls. The globe of each eye was cut through the cornea and embedded in paraffin. Serial sections were stained with hematoxylin-eosin for quantification of neovascular nuclei. The avidin-biotin peroxidase method was performed for evaluation of VEGF expression. The average number of neovascular nuclei was significantly lower in the control group compared to that in the ROP groups. In addition, it significantly decreased in the RA-treated ROP group compared to that of the saline-administrated ROP group. VEGF immunostaining was overall negative in room air-exposed rats. The VEGF immunostaining score significantly decreased in the RA-treated ROP group compared to that in the saline-administered ROP group. RA treatment might be beneficial in preventing neovascularization resulting from oxygen-induced retinopathy by downregulation of VEGF expression.

Published
2006

42. Once-monthly continuous erythropoietin receptor activator (CERA) for haemoglobin maintenance in haemodialysis patients with chronic renal anaemia

Author

Duman, N., primary, Uyanik, A., additional, Unsal, A., additional, Sezer, S., additional, Camsari, T., additional, Cirit, M., additional, Yilmaz, M. E., additional, Altun, B., additional, Duranay, M., additional, Yildiz, A., additional, Sahin, I., additional, Dogukan, A., additional, Ustundag, S., additional, Karayaylali, I., additional, Kahveci, A., additional, Sindel, S., additional, Kiykim, A. A., additional, Yenicerioglu, Y., additional, Akbas, E., additional, and Ozdener, F., additional

Published
2014
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44. Intracranial hemorrhage and hematuria in a neonate associated with heavy maternal smoking

Author

Duman N, Oren H, Duman M, and Hasan Ozkan

Abstract

Maternal smoking during pregnancy is associated with greater rates of premature deliveries, low birth weight, perinatal morbidity and mortality, and impaired intellectual development. It also causes a three-fold greater risk for intracranial hemorrhage in neonates. To our knowledge no neonatal case with, intracranial hemorrhage and hematuria related to heavy maternal smoking has been published to date. In this case report we present a neonate with intracranial hemorrhage and hematuria, which were associated with heavy maternal smoking, to emphasize the importance of heavy maternal smoking as a causal factor in neonatal bleeding.

Published
2003

46. Goldston syndrome: Report of a case

Author

Yh, Gulcan, Duman N, Kumral A, Sağol, Lebe B, Kavukçu S, Erçal D, Celiloğlu M, and Hasan Ozkan

Subjects
Adult, Liver Cirrhosis, Male, Polycystic Kidney Diseases, Infant, Newborn, Brain, Syndrome, Nervous System Malformations, Fetal Diseases, Pregnancy, Karyotyping, Prenatal Diagnosis, Humans, Abnormalities, Multiple, Female, Dandy-Walker Syndrome, Lung, Ultrasonography
Abstract

Goldston Syndrome: report of a case: Cerebrohepatorenal malformation is a rare familial disorder characterized by typical renal lesions combined with Dandy-Walker malformation, and congenital hepatic fibrosis. In this case report, a male premie with the diagnosis of cerebrorenal syndrome or so called Goldston syndrome is presented. Besides the rarity of this syndrome, this case is the second reported patient diagnosed prenatally.

Published
2001

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