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Background: This paper reviews some of the literature on the safety and efficacy of different COVID-19 vaccines, the attitudes, and perceptions of people towards the vaccines, and the factor underlying such perceptions and behavior. Methods: Two major databases (PubMed and Epistemonikos) were checked using search expansion mechanisms and several search strings. After the title, abstract, and full-text analysis, 19 studies were selected for review. Results: The seven different vaccines studied all have supporting data on their efficacy in the reduction of COVID-19 cases, prevention of hospitalization after infection, and reduction in the mortality rate of COVID-19 patients. There was high hesitancy about the COVID-19 vaccine and the perceived efficacy and safety of the vaccines are less than recorded in clinical data. Distrust of the vaccines, their manufacturers and different institutions and governments, personal beliefs and feelings, age, gender, education, and socioeconomic status were identified factors affecting behaviors towards the COVID-19 vaccines. Conclusion: Several articles support the efficacy of COVID-19 vaccines, but general awareness and conception about them vary, including hesitancy, distrust, and some acceptance. Many factors affected the perception and attitude of people toward these vaccines. More clinical data on the efficacy and safety of COVID-19 vaccines should be generated to help boost confidence among users. Résumé Contexte: Cet article passe en revue une partie de la littérature sur l'innocuité et l'efficacité de différents vaccins COVID-19, les attitudes et les perceptions des personnes à l'égard des vaccins, ainsi que les facteurs sous-jacents et le facteur sous-jacent à ces perceptions et comportements. Méthode: Deux bases de données majeures (PubMed et Epistemonikos) ont été vérifiées à l'aide de mécanismes d'expansion de la recherche et de plusieurs chaînes de recherche. Après l'analyse du titre, du résumé et du texte intégral, 19 études ont été sélectionnées pour examen. Résultat: Les 7 vaccins différents étudiés ont tous des données à l'appui sur leur efficacité dans la réduction des cas de COVID-19, la prévention des hospitalisations après infection et la réduction du taux de mortalité des patients COVID-19. Il y avait une grande hésitation à propos du vaccin COVID-19 et l'efficacité et l'innocuité perçues des vaccins sont inférieures à celles enregistrées dans les données cliniques. La méfiance à l'égard des vaccins, de leurs fabricants et des différentes institutions et gouvernements, les croyances et sentiments personnels, l'âge, le sexe, l'éducation et le statut socio-économique ont été identifiés comme des facteurs affectant les comportements à l'égard des vaccins COVID-19. Conclusion: Plusieurs articles soutiennent l'efficacité des vaccins COVID-19, mais la sensibilisation et la conception générales à leur sujet varient, y compris l'hésitation, la méfiance et une certaine acceptation. De nombreux facteurs ont affecté la perception et l'attitude des gens envers ces vaccins. Plus de données cliniques sur l'efficacité et l'innocuité des vaccins COVID-19 devraient être générées pour aider à renforcer la confiance des utilisateurs. Mots-clés: Attitude, COVID-19, vaccins COVID-19, efficacité, innocuité [ABSTRACT FROM AUTHOR]

Background: This paper reviews some of the literature on the safety and efficacy of different COVID-19 vaccines, the attitudes, and perceptions of people towards the vaccines, and the factor underlying such perceptions and behavior. Methods: Two major databases (PubMed and Epistemonikos) were checked using search expansion mechanisms and several search strings. After the title, abstract, and full-text analysis, 19 studies were selected for review. Results: The seven different vaccines studied all have supporting data on their efficacy in the reduction of COVID-19 cases, prevention of hospitalization after infection, and reduction in the mortality rate of COVID-19 patients. There was high hesitancy about the COVID-19 vaccine and the perceived efficacy and safety of the vaccines are less than recorded in clinical data. Distrust of the vaccines, their manufacturers and different institutions and governments, personal beliefs and feelings, age, gender, education, and socioeconomic status were identified factors affecting behaviors towards the COVID-19 vaccines. Conclusion: Several articles support the efficacy of COVID-19 vaccines, but general awareness and conception about them vary, including hesitancy, distrust, and some acceptance. Many factors affected the perception and attitude of people toward these vaccines. More clinical data on the efficacy and safety of COVID-19 vaccines should be generated to help boost confidence among users. [ABSTRACT FROM AUTHOR]