184 results on '"Dupas, S"'
Search Results
2. The Cotesia sesamiae story: insight into host-range evolution in a Hymenoptera parasitoid and implication for its use in biological control programs
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Kaiser, L., Dupas, S., Branca, A., Herniou, E. A., Clarke, C. W., Capdevielle Dulac, C., Obonyo, J., Benoist, R., Gauthier, J., Calatayud, P. A., Silvain, J. F., and Le Ru, B. P.
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- 2017
- Full Text
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3. Incidence and predictors of venous thromboembolism recurrence after a first isolated distal deep vein thrombosis
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Galanaud, J.‐P., Sevestre, M.‐A., Genty, C., Kahn, S.R., Pernod, G., Rolland, C., Diard, A., Dupas, S., Jurus, C., Diamand, J.‐M., Quere, I., and Bosson, J.‐L.
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- 2014
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4. Reconstructing the invasion and the demographic history of the yellow-legged hornet, Vespa velutina, in Europe
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Arca, M., Mougel, F., Guillemaud, T., Dupas, S., Rome, Q., Perrard, A., Muller, F., Fossoud, A., Capdevielle-Dulac, C., Torres-Leguizamon, M., Chen, X. X., Tan, J. L., Jung, C., Villemant, C., Arnold, G., and Silvain, J.-F.
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- 2015
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5. Inferring native range and invasion scenarios with mitochondrial DNA: the case of T. solanivora successive north–south step-wise introductions across Central and South America
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Torres-Leguizamón, M., Dupas, S., Dardon, D., Gómez, Y., Niño, L., Carnero, A., Padilla, A., Merlin, I., Fossoud, A., Zeddam, J.-L., Lery, X., Capdevielle-Dulac, C., Dangles, O., and Silvain, J.-F.
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- 2011
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6. Genetic bottleneck in invasive species: the potato tuber moth adds to the list
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Puillandre, N., Dupas, S., Dangles, O., Zeddam, J.-L., Capdevielle-Dulac, C., Barbin, K., Torres-Leguizamon, M., and Silvain, J.-F.
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- 2008
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7. Population genetics of the Mediterranean corn borer (Sesamia nonagrioides) differs between wild and cultivated plants
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Naino Jika, Abdel Kader, Le Ru, B., Capdevielle-Dulac, C., Chardonnet, F., Silvain, J. F., Kaiser, L., Dupas, S., Evolution, génomes, comportement et écologie (EGCE), Institut de Recherche pour le Développement (IRD)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), and Institut de Recherche pour le Développement (IRD)-Centre National de la Recherche Scientifique (CNRS)-Université Paris-Saclay
- Subjects
Topography ,[SDV]Life Sciences [q-bio] ,Plant Science ,Moths ,Plant Genetics ,Geographical locations ,ComputingMilieux_MISCELLANEOUS ,Geography ,Eukaryota ,food and beverages ,Agriculture ,Plants ,Europe ,Insects ,Phylogeography ,Experimental Organism Systems ,Biogeography ,Moths and Butterflies ,Medicine ,France ,Research Article ,Valleys ,Arthropoda ,Science ,Research and Analysis Methods ,Zea mays ,Host-Parasite Interactions ,Model Organisms ,Plant and Algal Models ,Genetics ,Animals ,Grasses ,European Union ,Evolutionary Biology ,Landforms ,Population Biology ,Ecology and Environmental Sciences ,fungi ,Organisms ,Biology and Life Sciences ,Genetic Variation ,Geomorphology ,Bayes Theorem ,Invertebrates ,Maize ,Genetics, Population ,Animal Studies ,Earth Sciences ,People and places ,Population Genetics - Abstract
The population genetic structure of crop pest populations gives information about their spatial ecology, which helps in designing management strategies. In this paper, we investigated the genetic structure of the Mediterranean Corn Borer (MCB), Sesamia nonagrioides Lefèbvre (Lepidoptera: Noctuidae), one of the most important maize pests in the Mediterranean countries, using microsatellite markers for the first time in this species. Insects were collected in twenty-five locations in southwest and southeast France from cultivated and wild host plants (Zea mays, Sorghum halepense and Typha domingensis). Contrary to what has been reported so far in France, we found that MCB populations could be locally abundant on wild poales plants. Analysis was carried out at 11 polymorphic microsatellite markers. Molecular variance was significantly determined by geography, then by host plant, with 17% and 4%, respectively, when considered as a major effect, and with 14% and 1%, respectively, when considered as a marginal effect in permutational analysis. Multidimensional scaling (MDS) and GENELAND Bayesian clustering suggested that populations infecting wild plants (T. domingensis and S. halepense) were more structured locally than those affecting cultivated maize. In S. halepense, significant Isolation By Distance (IBD) indicated that this factor could explain genetic differentiation of the moth populations. In T. domingensis, local population differentiation was strong but did not depend on distance. The implication of this absence of population structure in maize and the heterogeneity of population genetics patterns in wild plants are discussed in the context of the population dynamics hypothesis and population management strategies.
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- 2020
8. Chromosomal resolution reveals symbiotic virus colonization of parasitic wasp genomes
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Gauthier, J., Boulain, H., van Vugt, J.F.A., Baudry, L., Persyn, E., Aury, J.M., Noel, B., Bretaudeau, A., Legeai, Fabrice, Warris, S., Amine Chebbi, M., Dubreuil, Géraldine, Duvic, Bernard, Kremer, Natacha, Gayral, P., Musset, K., Thibaut, J., Bigot, D., Bressac, C., Moreau, S., Periquet, G., Harry, M., Montagné, N., Boulogne, I., Sabeti-Azad, M., Maïbèche, M., Chertemps, T., Hilliou, F., Siaussat, D., Amselem, J., Luyten, I., Capdevielle-Dulac, C., Labadie, Karine, Laís Merlin, B., Barbe, Valérie, de Boer, J.G., Marbouty, M., Cônsoli, F.L., Dupas, S., Hua Van, A., Le Goff, G., Bézier, Annie, Jacquin-Joly, E., Whitfield, James B., Vet, L.E.M., Smid, H.M., Kaiser-Arnault, L., Koszul, R., Huguet, Elisabeth, Herniou, Elisabeth A., and Drezen, J.M.
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BIOS Applied Bioinformatics ,fungi ,Life Science ,Laboratory of Entomology ,Laboratorium voor Entomologie - Abstract
Most endogenous viruses, an important proportion of eukaryote genomes, are doomed to slowly decay. Little is known, however, on how they evolve when they confer a benefit to their host. Bracoviruses are essential for the parasitism success of parasitoid wasps, whose genomes they integrated ~103 million years ago. Here we show, from the assembly of a parasitoid wasp genome, for the first time at a chromosomal scale, that symbiotic bracovirus genes spread to and colonized all the chromosomes. Moreover, large viral clusters are stably maintained suggesting strong evolutionary constraints. Genomic comparison with another wasps revealed that this organization was already established ~53 mya. Transcriptomic analyses highlight temporal synchronization of viral gene expression, leading to particle production. Immune genes are not induced, however, indicating the virus is not perceived as foreign by the wasp. This recognition suggests that no conflicts remain between symbiotic partners when benefits to them converge.
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- 2020
9. Chapter 11 Local, Geographic and Phylogenetic Scales of Coevolution in Drosophila–Parasitoid Interactions
- Author
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Dupas, S., primary, Dubuffet, A., additional, Carton, Y., additional, and Poirié, M., additional
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- 2009
- Full Text
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10. Chapter 6 Variation of Leptopilina boulardi Success in Drosophila Hosts
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Dubuffet, A., primary, Colinet, D., additional, Anselme, C., additional, Dupas, S., additional, Carton, Y., additional, and Poirié, M., additional
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- 2009
- Full Text
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11. Two non-linked genes for specific virulence of Leptopilina boulardi against Drosophila melanogaster and D. yakuba
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Dupas, S. and Carton, Y.
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- 1999
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12. A single parasitoid segregating factor controls immune suppression in Drosophila
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Dupas, S., Frey, F., and Carton, Y.
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Drosophila -- Research ,Parasites -- Research ,Immunosuppression -- Research ,Biological sciences - Abstract
The parasitoid Leptopilina boulardi has been found to suppress the immune reaction of Drosophila melanogaster hosts through the injection of virus-like particles. The hypothesis that this ability is regulated by a single chromosomal factor with semidominant effect was investigated. The range of possible genotypic values in back-crosses was examined utilizing various progeny that were genotypically homogenous. Findings contradict the polygenic effect for a trait governing the interaction between the insect and the parasitoid.
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- 1998
13. The management of acute venous thromboembolism in clinical practice - study rationale and protocol of the European PREFER in VTE Registry
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Agnelli, G., Gitt, A. K., Bauersachs, R., Fronk, E. -M., Laeis, P., Mismetti, P., Monreal, M., Willich, S. N., Wolf, W. -P., Cohen, A. T., Brodmann, M., Rief, P., Eischer, L., Stoshikj, S., Hirschl, M., Weinmann, S., Marschang, P., Abbadie, F., Achkar, A., Addala, A., Adnet, F., Alexandra, J. -F., Aquilanti, S., Belhassane, A., Benaroya, A., Berremili, T., Grenot, M. C., Birr, V., Holtea, D., Bonnin, C., Bosler, F., Durand, M. -G. B., Brisot, D., Brousse, C., De La Fuente, T., Cayman, R., Cazaubon, M., Champion, O., Chanut, M., Chevalet, P., Connault, J., Durant, C., Constans, J., Cordeanu, M., Couturaud, F., Lacut, K., De Dedker, L., Decoulx, E., Derrien, B., Diamand, J. -M., Diard, A., Douadi, Y., Dupas, S., Remond, S. S. M., Sevestre, M. -A., Edhery, S., Falvo, N., Taralunga, C. F., Ferrari, E., Gaillard, C., Garrigues, D., Gillet, J. L., Giordana, P., Grange, C., Vital-Durand, D., Grare, F., Henni, A. H., Heuser, S., Schmidt, J., Hidden-Henic, V., Hottin, D., Imbert, B., Pernod, G., Jakob, D., Jacquinandi, V., Jurus, C., Lacoste, A., Laroche, J. -P., Martin, M., Mazollier, C., Mersel, T., Miserey, G., Nedey, C., Nou, M., Quere, I., Ouvry, P., Peuch, B., Pichot, O., Poulain, V., Ray, P., Rifai, A., Roy, P. -M., Saby, J. -C., Simon, F., Simonot-Lalandec, E., Stephan, D., Tissot, A., Vodoungnon, H., Adamczyk, A., Schnabl, S., Ahmad, W. A., Weber, H., Axthelm, C., Bergmann, K., Beschorner, U., Knittel, M., Binias, K. -H., Pasligh, M., Boral, M., Friederike, G., Bratsch, H., Brauer, G., Burghard, S., Demann, C., Rennebaum, C., Demmig, A., Eberlein, U., Enger, F., Eschenburg, J., Forkmann, L., Frank, J., Freischmidt, H., Gassauer, M., Fritsche, I., Kubicek-Hofmann, C., Goebels, M. -C., Guggenbichler, S., Hartel, D., Hartmann, K., Heilberger, P., Heinsius, A., Held, M., Schnupp, S., Herman, G., Herold, J., Hertrich, F., Hommel, H., Hutte, G., Kalka, C., Jungandreas, K., Ramthor, M., Karcher, J., Werner, N., Karl-Wollweber, S., Keilhau, D. -A., Kittel, K., Knolinski, T., Kohler, C., Werth, S., Kopplin, U., Korner, I., Wittig, K., Kroger, K., Moysidis, T., Kroschel, U., Leschke, M., zur Nieden, T., Lubbert, G., Lutz, A., Wucherpfennig, P., Marencke, G. -H., Mortensen, K., Reppel, M., Nelles, H., Nestler, K., Neumeister, A., Schlosser, A., Oettler, W., Ott, I., Otto, A., Pertermann, A., Pfister, R., Pindur, L., Pourhassan, S., Predel, D., Pudollek, T., Reimer, D., Richter, C., Rieker, E., Rothenbucher, G., Rothhagen, B., Rudolff, S., Stucker, M., Schafer, A., Sonnenschein, K., Schafnitzl, W., Schellong, S., Voigts, B., Schiller, M., Schmeink, T., Schneider, H., Schon, N., Schulze, M., Sechtem, U., Sedl, S., Werno, H. S., Stachowitz, J., Thieme, M., Tiefenbacher, C., Tsantilas, D., Vieth, P., vom Dahl, J., Grun-Himmelmann, K., von Bilderling, P., von Maltik, T., Weinrich, K., Weyer, M., Koln, E. K., Wirtz, P., Wittig, I., Zierock, P., Ageno, W., Caprioli, M., Rancan, E., Guercini, F., Mommi, V., Amitrano, M., Cannavacciuolo, F., Amore, M., D'Antoni, S., Angelini, E., Forgia, S. L., Antignani, P. L., Calandra, G., Arone, A., Perticone, F., Sciacqua, A., Asaro, G., Bellisi, M., Attanzio, M. T., Pinto, A., Attinasi, V., Cillari, E., Sorvillo, S., Balbarini, A., Santini, C., Violo, C., Banfi, E., Lodigiani, C., Barcellona, D., Delpin, S., Marongiu, S., Barillari, G., Pasca, S, Bartolini, C., Verdecchia, P., Bartone, M., Mancuso, G., Bellanuova, I., Felis, S., Bellizzi, A., Masotti, L., Bianchi, M., Carugati, A., Bianchini, G., Guarnera, G., Boari, B., Gallerani, M., Pasin, M., Bortoluzzi, C., Parisi, R., Brucoli, C., Palasciano, G., Camporese, G., Tonello, C., Canafoglia, L., Rupoli, S., Cancellieri, E., Paoletti, O., Testa, S., Carlizza, A., Carnovali, M., Sada, S., Samaden, A., Casarsa, C., Mearelli, F., Pivetti, G., Catalini, R., Zingaretti, O., Vascolare, M., Cavazza, S., Cosmi, B., Cenci, C., Prisco, D., Silvestri, E., Ceresa, F., Patane, F., Ciampa, A., Siniscalchi, V., Ciarambino, T., De Bartolomeo, G., Clemente, M., Conti, F., Paiella, L., D'Avino, M., D'Alessandro, A., Placentino, M., Sollazzo, V., D'Angelo, A., Vigano, S., De Campora, P., Sangiuolo, R., De Franciscis, S., Serra, R., De Gaudenzi, E., De Santis, F., Piccinni, G. C., De Tommaso, I. D., Di Francesco, L., Vincentelli, G. M., Di Maggio, R., Saccullo, G., Siragusa, S., Di Micco, P., Fontanella, A., Di Michele, D., Di Minno, G., Tufano, A., Di Nisio, M., Porreca, E., Donadio, F., Imberti, D., Enea, I., Fabbian, F., Manfredini, R., Pala, M., Falanga, A., Milesi, V., Fiore, V., Franco, E., Giudice, G., Frausini, G., Rovinelli, M., Fuorlo, M., Landolfi, R., Morretti, T., Gamberini, S., Salmi, R., Ghirarduzzi, A., Veropalumbo, M. R., Ghizzi, M., Pepe, C., Gianniello, F., Martinelli, I., Iosub, D. I., Piovella, F., Iozzi, E., Talerico, A., Regina, M. L., Orlandini, F., Marconi, L., Palla, A., Marcucci, R., Poli, D., Margheriti, R., Sala, G., Marra, A., Marrocco, F., Montagna, E. S., Silvestris, F., Vallarelli, S., Mos, L., Rossetto, V., Mugno, F., Di Salvo, M., Nitti, C., Pennacchioni, M., Salvi, A., Olivieri, O., Tosi, F., Zorzi, F., Onesta, M., Pagliara, V., Villalta, S., Paolucci, G., Severino, S., Pierri, F., Russo, V., Pizzini, A. M., Quintavalla, R., Rubino, P., Ria, L., Schenone, A., Strafino, C., Tropeano, P., Vetrano, A., Zanatta, N., Cansino, M. D. A., Gutierrez, J. A., de las Revillas, F. A., Fernandez, C. A., Mijares, N. C., Blanco-Molina, M. A., Garcia, M. A., Seijo, D. J., Blazquez, R. A., Lopez-Saez, J. -B., Rodrigo, E. A., Blanch, J. V., Arxe, A. A., Dalmau, F. G. -B., Quincoces, A. B., Loizaga, A. G., Perez, J. L. B., Diaz, P. B., Loaiza, A. Q., Castellote, M. C., Alcantara, I. C., Padierna, M. L., Exposito, M. C., Mas, A. C., Castro, F. C., Sanz, R. C., de Saracho, J. O., de la Fuente, E. C., de Ancos Aracil, C., Ruiz, J. R., de Daborenea Gonzalez, M. D., Iglesias, A. F., de la Fuente Aguado, J., Gonzalez, L. G., del Carmen Fernandez-Capitan, M., Hernandez, A. L., del Toro Cervera, J., Rus, G. P., Bregel, J. L. D., Fernandez, F. D., Teresa Elias Hernandez, Palomares, L. J., Bataler, R. F., Rodriguez, J. A. N., Garcia, J. M. G., Porras, J. R. G., Garcia, M. G., Lopez, E. H., Lazaro, A. R., Jaras, M. J., Castro, D. J., Madridejos, R. J. -R., Navas, J. M. P., Lecumberri, R., Martinez, N., Castellanos, G. T. L., Espinosa, L. M., Jimenez, L. L., Cobo, O. M., Saiz, C. M., Pizarro, Y. R., Yglesias, P. J. M., Martin del Pozo, M., Melibovsky, L., Altarriba, E. S., Bosch, M. M., Secades, R. M., Lujan, J. M. M., Mestre, A. R., Moral, P. M., Parra, J. A. T., Flores, A. M., Munoz-Torrero, J. F. S., Rodriguez, F. J. M., Fernandez, M. J. N., Sibajas, E. O., de Sedas, M. V., Caballero, P. P., del Campo, I. P. M., Sanchez, J. P., Gallego, A. R., Alvarez, I. V., Beltran, E. M. R., Fuentes, D. S., Schilling, V. R., Alvarez, J. S., Lopez, G. T., Caralt, J. M. S., Miranda, R. T., de Antonio, E. U., Banyai, M., Frank, U., Gian Reto Jorg, Jeanneret, C., Staub, D., Ackroyd, S., Agarwal, G., Mearns, B., Alikhan, R., Allameddine, A., Al-Refaie, F., Arden, C., Austin, A., Bakhai, A., Barton, T., Ewad, H., Body, R., Thachil, J., Chacko, J., Chandra, D., Charters, F., Church, A., Mcgrane, F., Clements, J., Clifford, P., Cox, D., Crouch, M., Crowther, M., Davies, E., Davies, M., Dimitri, S., Drebes, A., Franklin, S., George, J., Irvine, N., Gerofke, H., Gibbs, C., Goh, T., Gupta, S., Holmes, J., Jackson-Voyzey, E., Jones, N., Kallat, A., Kerr, P., Kesteven, P., Lench, T., Lester, W., Lowe, G., Lewis, M., Mccormack, T., Mccoye, A., Moriarty, A., Morris, W., Myers, B., Narayanan, M., Oo, N., Reed, M., Rose, P., Saja, K., Sivakumaran, M., Sohal, M., Solomons, G., Sultanzadeh, S. J., Venton, T., Wakeling, J., Walby, C., Waldron, M., Watt, S., Willcock, W., Agnelli, G., Gitt, A. K., Bauersachs, R., Fronk, E. -M., Laeis, P., Mismetti, P., Monreal, M., Willich, S. N., Wolf, W. -P., Cohen, A. T., Brodmann, M., Rief, P., Eischer, L., Stoshikj, S., Hirschl, M., Weinmann, S., Marschang, P., Abbadie, F., Achkar, A., Addala, A., Adnet, F., Alexandra, J. -F., Aquilanti, S., Belhassane, A., Benaroya, A., Berremili, T., Grenot, M. C., Birr, V., Holtea, D., Bonnin, C., Bosler, F., Durand, M. -G. B., Brisot, D., Brousse, C., De La Fuente, T., Cayman, R., Cazaubon, M., Champion, O., Chanut, M., Chevalet, P., Connault, J., Durant, C., Constans, J., Cordeanu, M., Couturaud, F., Lacut, K., De Dedker, L., Decoulx, E., Derrien, B., Diamand, J. -M., Diard, A., Douadi, Y., Dupas, S., Remond, S. S. M., Sevestre, M. -A., Edhery, S., Falvo, N., Taralunga, C. F., Ferrari, E., Gaillard, C., Garrigues, D., Gillet, J. L., Giordana, P., Grange, C., Vital-Durand, D., Grare, F., Henni, A. H., Heuser, S., Schmidt, J., Hidden-Henic, V., Hottin, D., Imbert, B., Pernod, G., Jakob, D., Jacquinandi, V., Jurus, C., Lacoste, A., Laroche, J. -P., Martin, M., Mazollier, C., Mersel, T., Miserey, G., Nedey, C., Nou, M., Quere, I., Ouvry, P., Peuch, B., Pichot, O., Poulain, V., Ray, P., Rifai, A., Roy, P. -M., Saby, J. -C., Simon, F., Simonot-Lalandec, E., Stephan, D., Tissot, A., Vodoungnon, H., Adamczyk, A., Schnabl, S., Ahmad, W. A., Weber, H., Axthelm, C., Bergmann, K., Beschorner, U., Knittel, M., Binias, K. -H., Pasligh, M., Boral, M., Friederike, G., Bratsch, H., Brauer, G., Burghard, S., Demann, C., Rennebaum, C., Demmig, A., Eberlein, U., Enger, F., Eschenburg, J., Forkmann, L., Frank, J., Freischmidt, H., Gassauer, M., Fritsche, I., Kubicek-Hofmann, C., Goebels, M. -C., Guggenbichler, S., Hartel, D., Hartmann, K., Heilberger, P., Heinsius, A., Held, M., Schnupp, S., Herman, G., Herold, J., Hertrich, F., Hommel, H., Hutte, G., Kalka, C., Jungandreas, K., Ramthor, M., Karcher, J., Werner, N., Karl-Wollweber, S., Keilhau, D. -A., Kittel, K., Knolinski, T., Kohler, C., Werth, S., Kopplin, U., Korner, I., Wittig, K., Kroger, K., Moysidis, T., Kroschel, U., Leschke, M., zur Nieden, T., Lubbert, G., Lutz, A., Wucherpfennig, P., Marencke, G. -H., Mortensen, K., Reppel, M., Nelles, H., Nestler, K., Neumeister, A., Schlosser, A., Oettler, W., Ott, I., Otto, A., Pertermann, A., Pfister, R., Pindur, L., Pourhassan, S., Predel, D., Pudollek, T., Reimer, D., Richter, C., Rieker, E., Rothenbucher, G., Rothhagen, B., Rudolff, S., Stucker, M., Schafer, A., Sonnenschein, K., Schafnitzl, W., Schellong, S., Voigts, B., Schiller, M., Schmeink, T., Schneider, H., Schon, N., Schulze, M., Sechtem, U., Sedl, S., Werno, H. S., Stachowitz, J., Thieme, M., Tiefenbacher, C., Tsantilas, D., Vieth, P., vom Dahl, J., Grun-Himmelmann, K., von Bilderling, P., von Maltik, T., Weinrich, K., Weyer, M., Koln, E. K., Wirtz, P., Wittig, I., Zierock, P., Ageno, W., Caprioli, M., Rancan, E., Guercini, F., Mommi, V., Amitrano, M., Cannavacciuolo, F., Amore, M., D'Antoni, S., Angelini, E., Forgia, S. L., Antignani, P. L., Calandra, G., Arone, A., Perticone, F., Sciacqua, A., Asaro, G., Bellisi, M., Attanzio, M. T., Pinto, A., Attinasi, V., Cillari, E., Sorvillo, S., Balbarini, A., Santini, C., Violo, C., Banfi, E., Lodigiani, C., Barcellona, D., Delpin, S., Marongiu, S., Barillari, G., Pasca, S., Bartolini, C., Verdecchia, P., Bartone, M., Mancuso, G., Bellanuova, I., Felis, S., Bellizzi, A., Masotti, L., Bianchi, M., Carugati, A., Bianchini, G., Guarnera, G., Boari, B., Gallerani, M., Pasin, M., Bortoluzzi, C., Parisi, R., Brucoli, C., Palasciano, G., Camporese, G., Tonello, C., Canafoglia, L., Rupoli, S., Cancellieri, E., Paoletti, O., Testa, S., Carlizza, A., Carnovali, M., Sada, S., Samaden, A., Casarsa, C., Mearelli, F., Pivetti, G., Catalini, R., Zingaretti, O., Vascolare, M., Cavazza, S., Cosmi, B., Cenci, C., Prisco, D., Silvestri, E., Ceresa, F., Patane, F., Ciampa, A., Siniscalchi, V., Ciarambino, T., De Bartolomeo, G., Clemente, M., Conti, F., Paiella, L., D'Avino, M., D'Alessandro, A., Placentino, M., Sollazzo, V., D'Angelo, A., Vigano, S., De Campora, P., Sangiuolo, R., De Franciscis, S., Serra, R., De Gaudenzi, E., De Santis, F., Piccinni, G. C., De Tommaso, I. D., Di Francesco, L., Vincentelli, G. M., Di Maggio, R., Saccullo, G., Siragusa, S., Di Micco, P., Fontanella, A., Di Michele, D., Di Minno, G., Tufano, A., Di Nisio, M., Porreca, E., Donadio, F., Imberti, D., Enea, I., Fabbian, F., Manfredini, R., Pala, M., Falanga, A., Milesi, V., Fiore, V., Franco, E., Giudice, G., Frausini, G., Rovinelli, M., Fuorlo, M., Landolfi, R., Morretti, T., Gamberini, S., Salmi, R., Ghirarduzzi, A., Veropalumbo, M. R., Ghizzi, M., Pepe, C., Gianniello, F., Martinelli, I., Iosub, D. I., Piovella, F., Iozzi, E., Talerico, A., Regina, M. L., Orlandini, F., Marconi, L., Palla, A., Marcucci, R., Poli, D., Margheriti, R., Sala, G., Marra, A., Marrocco, F., Montagna, E. S., Silvestris, F., Vallarelli, S., Mos, L., Rossetto, V., Mugno, F., Di Salvo, M., Nitti, C., Pennacchioni, M., Salvi, A., Olivieri, O., Tosi, F., Zorzi, F., Onesta, M., Pagliara, V., Villalta, S., Paolucci, G., Severino, S., Pierri, F., Russo, V., Pizzini, A. M., Quintavalla, R., Rubino, P., Ria, L., Schenone, A., Strafino, C., Tropeano, P., Vetrano, A., Zanatta, N., Cansino, M. D. A., Gutierrez, J. A., de las Revillas, F. A., Fernandez, C. A., Mijares, N. C., Blanco-Molina, M. A., Garcia, M. A., Seijo, D. J., Blazquez, R. A., Lopez-Saez, J. -B., Rodrigo, E. A., Blanch, J. V., Arxe, A. A., Dalmau, F. G. -B., Quincoces, A. B., Loizaga, A. G., Perez, J. L. B., Diaz, P. B., Loaiza, A. Q., Castellote, M. C., Alcantara, I. C., Padierna, M. L., Exposito, M. C., Mas, A. C., Castro, F. C., Sanz, R. C., de Saracho, J. O., de la Fuente, E. C., de Ancos Aracil, C., Ruiz, J. R., de Daborenea Gonzalez, M. D., Iglesias, A. F., de la Fuente Aguado, J., Gonzalez, L. G., del Carmen Fernandez-Capitan, M., Hernandez, A. L., del Toro Cervera, J., Rus, G. P., Bregel, J. L. D., Fernandez, F. D., Teresa Elias, Hernandez, Palomares, L. J., Bataler, R. F., Rodriguez, J. A. N., Garcia, J. M. G., Porras, J. R. G., Garcia, M. G., Lopez, E. H., Lazaro, A. R., Jaras, M. J., Castro, D. J., Madridejos, R. J. -R., Navas, J. M. P., Lecumberri, R., Martinez, N., Castellanos, G. T. L., Espinosa, L. M., Jimenez, L. L., Cobo, O. M., Saiz, C. M., Pizarro, Y. R., Yglesias, P. J. M., Martin del Pozo, M., Melibovsky, L., Altarriba, E. S., Bosch, M. M., Secades, R. M., Lujan, J. M. M., Mestre, A. R., Moral, P. M., Parra, J. A. T., Flores, A. M., Munoz-Torrero, J. F. S., Rodriguez, F. J. M., Fernandez, M. J. N., Sibajas, E. O., de Sedas, M. V., Caballero, P. P., del Campo, I. P. M., Sanchez, J. P., Gallego, A. R., Alvarez, I. V., Beltran, E. M. R., Fuentes, D. S., Schilling, V. R., Alvarez, J. S., Lopez, G. T., Caralt, J. M. S., Miranda, R. T., de Antonio, E. U., Banyai, M., Frank, U., Gian Reto, Jorg, Jeanneret, C., Staub, D., Ackroyd, S., Agarwal, G., Mearns, B., Alikhan, R., Allameddine, A., Al-Refaie, F., Arden, C., Austin, A., Bakhai, A., Barton, T., Ewad, H., Body, R., Thachil, J., Chacko, J., Chandra, D., Charters, F., Church, A., Mcgrane, F., Clements, J., Clifford, P., Cox, D., Crouch, M., Crowther, M., Davies, E., Davies, M., Dimitri, S., Drebes, A., Franklin, S., George, J., Irvine, N., Gerofke, H., Gibbs, C., Goh, T., Gupta, S., Holmes, J., Jackson-Voyzey, E., Jones, N., Kallat, A., Kerr, P., Kesteven, P., Lench, T., Lester, W., Lowe, G., Lewis, M., Mccormack, T., Mccoye, A., Moriarty, A., Morris, W., Myers, B., Narayanan, M., Oo, N., Reed, M., Rose, P., Saja, K., Sivakumaran, M., Sohal, M., Solomons, G., Sultanzadeh, S. J., Venton, T., Wakeling, J., Walby, C., Waldron, M., Watt, S., Willcock, W., Zafar, A., Agnelli, G, Gitt, A, Bauersachs, R, Fronk, E, Laeis, P, Mismetti, P, Monreal, M, Willich, S, Wolf, W, Cohen, A, Brodmann, M, Rief, P, Eischer, L, Stoshikj, S, Hirschl, M, Weinmann, S, Marschang, P, Abbadie, F, Achkar, A, Addala, A, Adnet, F, Alexandra, J, Aquilanti, S, Belhassane, A, Benaroya, A, Berremili, T, Grenot, M, Birr, V, Holtea, D, Bonnin, C, Bosler, F, Durand, M, Brisot, D, Brousse, C, De La Fuente, T, Cayman, R, Cazaubon, M, Champion, O, Chanut, M, Chevalet, P, Connault, J, Durant, C, Constans, J, Cordeanu, M, Couturaud, F, Lacut, K, De Dedker, L, Decoulx, E, Derrien, B, Diamand, J, Diard, A, Douadi, Y, Dupas, S, Remond, S, Sevestre, M, Edhery, S, Falvo, N, Taralunga, C, Ferrari, E, Gaillard, C, Garrigues, D, Gillet, J, Giordana, P, Grange, C, Vital-Durand, D, Grare, F, Henni, A, Heuser, S, Schmidt, J, Hidden-Henic, V, Hottin, D, Imbert, B, Pernod, G, Jakob, D, Jacquinandi, V, Jurus, C, Lacoste, A, Laroche, J, Martin, M, Mazollier, C, Mersel, T, Miserey, G, Nedey, C, Nou, M, Quere, I, Ouvry, P, Peuch, B, Pichot, O, Poulain, V, Ray, P, Rifai, A, Roy, P, Saby, J, Simon, F, Simonot-Lalandec, E, Stephan, D, Tissot, A, Vodoungnon, H, Adamczyk, A, Schnabl, S, Ahmad, W, Weber, H, Axthelm, C, Bergmann, K, Beschorner, U, Knittel, M, Binias, K, Pasligh, M, Boral, M, Friederike, G, Bratsch, H, Brauer, G, Burghard, S, Demann, C, Rennebaum, C, Demmig, A, Eberlein, U, Enger, F, Eschenburg, J, Forkmann, L, Frank, J, Freischmidt, H, Gassauer, M, Fritsche, I, Kubicek-Hofmann, C, Goebels, M, Guggenbichler, S, Hartel, D, Hartmann, K, Heilberger, P, Heinsius, A, Held, M, Schnupp, S, Herman, G, Herold, J, Hertrich, F, Hommel, H, Hutte, G, Kalka, C, Jungandreas, K, Ramthor, M, Karcher, J, Werner, N, Karl-Wollweber, S, Keilhau, D, Kittel, K, Knolinski, T, Kohler, C, Werth, S, Kopplin, U, Korner, I, Wittig, K, Kroger, K, Moysidis, T, Kroschel, U, Leschke, M, zur Nieden, T, Lubbert, G, Lutz, A, Wucherpfennig, P, Marencke, G, Mortensen, K, Reppel, M, Nelles, H, Nestler, K, Neumeister, A, Schlosser, A, Oettler, W, Ott, I, Otto, A, Pertermann, A, Pfister, R, Pindur, L, Pourhassan, S, Predel, D, Pudollek, T, Reimer, D, Richter, C, Rieker, E, Rothenbucher, G, Rothhagen, B, Rudolff, S, Stucker, M, Schafer, A, Sonnenschein, K, Schafnitzl, W, Schellong, S, Voigts, B, Schiller, M, Schmeink, T, Schneider, H, Schon, N, Schulze, M, Sechtem, U, Sedl, S, Werno, H, Stachowitz, J, Thieme, M, Tiefenbacher, C, Tsantilas, D, Vieth, P, vom Dahl, J, Grun-Himmelmann, K, von Bilderling, P, von Maltik, T, Weinrich, K, Weyer, M, Koln, E, Wirtz, P, Wittig, I, Zierock, P, Ageno, W, Caprioli, M, Rancan, E, Guercini, F, Mommi, V, Amitrano, M, Cannavacciuolo, F, Amore, M, D'Antoni, S, Angelini, E, Forgia, S, Antignani, P, Calandra, G, Arone, A, Perticone, F, Sciacqua, A, Asaro, G, Bellisi, M, Attanzio, M, Pinto, A, Attinasi, V, Cillari, E, Sorvillo, S, Balbarini, A, Santini, C, Violo, C, Banfi, E, Lodigiani, C, Barcellona, D, Delpin, S, Marongiu, S, Barillari, G, Pasca, S, Bartolini, C, Verdecchia, P, Bartone, M, Mancuso, G, Bellanuova, I, Felis, S, Bellizzi, A, Masotti, L, Bianchi, M, Carugati, A, Bianchini, G, Guarnera, G, Boari, B, Gallerani, M, Pasin, M, Bortoluzzi, C, Parisi, R, Brucoli, C, Palasciano, G, Camporese, G, Tonello, C, Canafoglia, L, Rupoli, S, Cancellieri, E, Paoletti, O, Testa, S, Carlizza, A, Carnovali, M, Sada, S, Samaden, A, Casarsa, C, Mearelli, F, Pivetti, G, Catalini, R, Zingaretti, O, Vascolare, M, Cavazza, S, Cosmi, B, Cenci, C, Prisco, D, Silvestri, E, Ceresa, F, Patane, F, Ciampa, A, Siniscalchi, V, Ciarambino, T, De Bartolomeo, G, Clemente, M, Conti, F, Paiella, L, D'Avino, M, D'Alessandro, A, Placentino, M, Sollazzo, V, D'Angelo, A, Vigano, S, De Campora, P, Sangiuolo, R, De Franciscis, S, Serra, R, De Gaudenzi, E, De Santis, F, Piccinni, G, De Tommaso, I, Di Francesco, L, Vincentelli, G, Di Maggio, R, Saccullo, G, Siragusa, S, Di Micco, P, Fontanella, A, Di Michele, D, Di Minno, G, Tufano, A, Di Nisio, M, Porreca, E, Donadio, F, Imberti, D, Enea, I, Fabbian, F, Manfredini, R, Pala, M, Falanga, A, Milesi, V, Fiore, V, Franco, E, Giudice, G, Frausini, G, Rovinelli, M, Fuorlo, M, Landolfi, R, Morretti, T, Gamberini, S, Salmi, R, Ghirarduzzi, A, Veropalumbo, M, Ghizzi, M, Pepe, C, Gianniello, F, Martinelli, I, Iosub, D, Piovella, F, Iozzi, E, Talerico, A, Regina, M, Orlandini, F, Marconi, L, Palla, A, Marcucci, R, Poli, D, Margheriti, R, Sala, G, Marra, A, Marrocco, F, Montagna, E, Silvestris, F, Vallarelli, S, Mos, L, Rossetto, V, Mugno, F, Di Salvo, M, Nitti, C, Pennacchioni, M, Salvi, A, Olivieri, O, Tosi, F, Zorzi, F, Onesta, M, Pagliara, V, Villalta, S, Paolucci, G, Severino, S, Pierri, F, Russo, V, Pizzini, A, Quintavalla, R, Rubino, P, Ria, L, Schenone, A, Strafino, C, Tropeano, P, Vetrano, A, Zanatta, N, Cansino, M, Gutierrez, J, de las Revillas, F, Fernandez, C, Mijares, N, Blanco-Molina, M, Garcia, M, Seijo, D, Blazquez, R, Lopez-Saez, J, Rodrigo, E, Blanch, J, Arxe, A, Dalmau, F, Quincoces, A, Loizaga, A, Perez, J, Diaz, P, Loaiza, A, Castellote, M, Alcantara, I, Padierna, M, Exposito, M, Mas, A, Castro, F, Sanz, R, de Saracho, J, de la Fuente, E, de Ancos Aracil, C, Ruiz, J, de Daborenea Gonzalez, M, Iglesias, A, de la Fuente Aguado, J, Gonzalez, L, del Carmen Fernandez-Capitan, M, Hernandez, A, del Toro Cervera, J, Rus, G, Bregel, J, Fernandez, F, Teresa Elias, H, Palomares, L, Bataler, R, Rodriguez, J, Garcia, J, Porras, J, Lopez, E, Lazaro, A, Jaras, M, Castro, D, Madridejos, R, Navas, J, Lecumberri, R, Martinez, N, Castellanos, G, Espinosa, L, Jimenez, L, Cobo, O, Saiz, C, Pizarro, Y, Yglesias, P, Martin del Pozo, M, Melibovsky, L, Altarriba, E, Bosch, M, Secades, R, Lujan, J, Mestre, A, Moral, P, Parra, J, Flores, A, Munoz-Torrero, J, Rodriguez, F, Fernandez, M, Sibajas, E, de Sedas, M, Caballero, P, del Campo, I, Sanchez, J, Gallego, A, Alvarez, I, Beltran, E, Fuentes, D, Schilling, V, Alvarez, J, Lopez, G, Caralt, J, Miranda, R, de Antonio, E, Banyai, M, Frank, U, Gian Reto, J, Jeanneret, C, Staub, D, Ackroyd, S, Agarwal, G, Mearns, B, Alikhan, R, Allameddine, A, Al-Refaie, F, Arden, C, Austin, A, Bakhai, A, Barton, T, Ewad, H, Body, R, Thachil, J, Chacko, J, Chandra, D, Charters, F, Church, A, Mcgrane, F, Clements, J, Clifford, P, Cox, D, Crouch, M, Crowther, M, Davies, E, Davies, M, Dimitri, S, Drebes, A, Franklin, S, George, J, Irvine, N, Gerofke, H, Gibbs, C, Goh, T, Gupta, S, Holmes, J, Jackson-Voyzey, E, Jones, N, Kallat, A, Kerr, P, Kesteven, P, Lench, T, Lester, W, Lowe, G, Lewis, M, Mccormack, T, Mccoye, A, Moriarty, A, Morris, W, Myers, B, Narayanan, M, Oo, N, Reed, M, Rose, P, Saja, K, Sivakumaran, M, Sohal, M, Solomons, G, Sultanzadeh, S, Venton, T, Wakeling, J, Walby, C, Waldron, M, Watt, S, Willcock, W, and Zafar, A
- Subjects
Drug Utilization ,Pediatrics ,medicine.medical_specialty ,Novel Oral Anticoagulants ,Registry ,Deep vein ,Alternative medicine ,Anticoagulation ,Patient satisfaction ,Quality of life ,Health care ,medicine ,Anticoagulation, Novel Oral Anticoagulants, Prevention, Registry, Venous Thromboembolism, Vitamin K antagonists ,cardiovascular diseases ,business.industry ,Prevention ,Venous Thromboembolism ,Vitamin K antagonists ,Hematology ,Novel Oral Anticoagulant ,medicine.disease ,equipment and supplies ,Pulmonary embolism ,medicine.anatomical_structure ,Emergency medicine ,Original Clinical Investigation ,Observational study ,business - Abstract
Background: Venous thromboembolism (VTE) is a major health problem, with over one million events every year in Europe. However, there is a paucity of data on the current management in real life, including factors influencing treatment pathways, patient satisfaction, quality of life (QoL), and utilization of health care resources and the corresponding costs. The PREFER in VTE registry has been designed to address this and to understand medical care and needs as well as potential gaps for improvement. Methods/design: The PREFER in VTE registry was a prospective, observational, multicenter study conducted in seven European countries including Austria, France Germany, Italy, Spain, Switzerland, and the UK to assess the characteristics and the management of patients with VTE, the use of health care resources, and to provide data to estimate the costs for 12 months treatment following a first-time and/or recurrent VTE diagnosed in hospitals or specialized or primary care centers. In addition, existing anticoagulant treatment patterns, patient pathways, clinical outcomes, treatment satisfaction, and health related QoL were documented. The centers were chosen to reflect the care environment in which patients with VTE are managed in each of the participating countries. Patients were eligible to be enrolled into the registry if they were at least 18 years old, had a symptomatic, objectively confirmed first time or recurrent acute VTE defined as either distal or proximal deep vein thrombosis, pulmonary embolism or both. After the baseline visit at the time of the acute VTE event, further follow-up documentations occurred at 1, 3, 6 and 12 months. Follow-up data was collected by either routinely scheduled visits or by telephone calls. Results: Overall, 381 centers participated, which enrolled 3,545 patients during an observational period of 1 year. Conclusion: The PREFER in VTE registry will provide valuable insights into the characteristics of patients with VTE and their acute and mid-term management, as well as into drug utilization and the use of health care resources in acute first-time and/or recurrent VTE across Europe in clinical practice. Trial registration: Registered in DRKS register, ID number: DRKS00004795
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- 2015
14. Novel promoters and coding first exons in DLG2 linked to developmental disorders and intellectual disability
- Author
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Létard, Pascaline, Drunat, Séverine, Vial, Yoann, Duerinckx, Sarah, Ernault, Anais, Amram, Daniel, Arpin, Stéphanie, Bertoli, Marta, Busa, Tiffany, Ceulemans, Berten, Desir, Julie, Doco-Fenzy, Martine, Elalaoui, Siham Chafai, Devriendt, Koenraad, Faivre, Laurence, Francannet, Christine, Geneviève, Geneviève, Gitiaux, Cyril, Julia, Sophie, Lebon, Sébastien, Lubala, Toni, Mathieu-Dramard, Michèle, Maurey, Hélène, Metreau, Julia, Nasserereddine, Sanaa, Nizon, Mathilde, Pierquin, Geneviève, Pouvreau, Nathalie, Rivier-Ringenbach, Clothilde, Rossi, Massimiliano, Schaefer, Elise, Sznajer, Yves, Tunca, Yusuf, Guilmin Crepon, Sophie, Alberti, Corinne, Elmaleh-Bergès, Monique, Benzacken, Brigitte, Wollnick, Bernd, Woods, C Geoffrey, Rauch, Anita, El Ghouzzi, Vincent, Gressens, Pierre, Verloes, Alain, Passemard, Sandrine, Geneviève, David, Julia, Julia, Woods, C. Geoffrey, Mordel, S, Schaeffer, Stéphane, Dupas, S., Laville, Marie-Alice, Chapon, Françoise, Allouche, S., Mordel, Patrick, Dupas, Quentin, Reggiani, Claudio, Coppens, Sandra, Sekhara, Tayeb, Dimov, Ivan, Pichon, Bruno, Lufin, Nicolas, Addor, Marie-Claude, Belligni, Elga Fabia, Digilio, Maria Cristina, Faletra, Flavio, Ferrero, Giovanni Battista, Gérard, Marion, Isidor, Bertrand, Joss, Shelagh, Niel-Bütschi, Florence, Perrone, Maria Dolores, Petit, Florence, Renieri, Alessandra, Romana, Serge, Topa, Alexandra, Vermeesch, Joris Robert, Lenaerts, Tom, Casimir, Georges, Abramowicz, Marc, Bontempi, Gianluca, Vilain, Catheline, Deconinck, Nicolas, Smits, Guillaume, Université libre de Bruxelles (ULB), Centre Hospitalier Universitaire Vaudois [Lausanne] (CHUV), University of Turin, IRCCS Ospedale Pediatrico Bambino Gesù [Roma], Institute for Maternal and Child Health - IRCCS 'Burlo Garofolo' [Trieste], Service de Génétique Clinique [CHU Caen], Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Normandie Université (NU)-CHU Caen, Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN)-Tumorothèque de Caen Basse-Normandie (TCBN), Service de génétique médicale - Unité de génétique clinique [Nantes], Université de Nantes (UN)-Centre hospitalier universitaire de Nantes (CHU Nantes), Queen Elizabeth University Hospital (Glasgow), Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Università degli Studi di Siena = University of Siena (UNISI), Laboratoire Histologie Embryologie Cytogénétique [CHU Necker], CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Sahlgrenska University Hospital [Gothenburg], Université Catholique de Louvain = Catholic University of Louvain (UCL), Universiteit Gent = Ghent University [Belgium] (UGENT), Hôpital Erasme [Bruxelles] (ULB), Faculté de Médecine [Bruxelles] (ULB), Université libre de Bruxelles (ULB)-Université libre de Bruxelles (ULB), Neuroprotection du Cerveau en Développement / Promoting Research Oriented Towards Early Cns Therapies (PROTECT), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Robert Debré-Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), AP-HP Hôpital universitaire Robert-Debré [Paris], UNIROUEN - UFR Santé (UNIROUEN UFR Santé), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU), Unité fonctionnelle de génétique clinique, Université Paris Diderot - Paris 7 (UPD7)-Hôpital Robert Debré-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Service de génétique [Tours], Centre Hospitalier Régional Universitaire de Tours (CHRU Tours)-Hôpital Bretonneau, Département de génétique médicale [Hôpital de la Timone - APHM], Aix Marseille Université (AMU)-Assistance Publique - Hôpitaux de Marseille (APHM)- Hôpital de la Timone [CHU - APHM] (TIMONE)-Institut National de la Santé et de la Recherche Médicale (INSERM), University of Antwerp (UA), Institut de Pathologie et Génétique [Gosselies] (I.P.G.), Service de Génétique, Centre Hospitalier Universitaire de Reims (CHU Reims)-Hôpital Maison Blanche-IFR 53, Université de Reims Champagne-Ardenne (URCA)-Université de Reims Champagne-Ardenne (URCA), Centre for Human Genetics, Catholic University of Leuven - Katholieke Universiteit Leuven (KU Leuven)-University Hospitals Leuven [Leuven], Centre Régional de Lutte contre le cancer Georges-François Leclerc [Dijon] (UNICANCER/CRLCC-CGFL), UNICANCER, Service de Génétique Médicale [CHU Clermont-Ferrand], CHU Clermont-Ferrand, Institut Cochin (IC UM3 (UMR 8104 / U1016)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Descartes - Paris 5 (UPD5)-Centre National de la Recherche Scientifique (CNRS), Service de génétique médicale [Toulouse], CHU Toulouse [Toulouse]-Hôpital Purpan [Toulouse], CHU Toulouse [Toulouse], Service de génétique médicale, CHU Amiens-Picardie, Service Neuropédiatrie, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Bicêtre, AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre), Centre de Génétique Humaine, Université de Liège-CHU Liège, Service de pédiatre-Néonatologie, CH Villefranche s/Saone, Centre de recherche en neurosciences de Lyon (CRNL), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet [Saint-Étienne] (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Hôpital de Hautepierre [Strasbourg], Medical Genetics, Epidémiologie Clinique et Evaluation Economique Appliquées aux Populations Vulnérables (ECEVE (U1123 / UMR_S_1123)), Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM)-AP-HP Hôpital universitaire Robert-Debré [Paris], Service d'imagerie pédiatrique, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Robert Debré-Université Paris Diderot - Paris 7 (UPD7), Département de génétique, Allergy Unit - Department of Dermatology, University of Zürich [Zürich] (UZH), Physiopathologie et neuroprotection des atteintes du cerveau en développement, Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), Département de génétique médicale, maladies rares et médecine personnalisée [CHRU Montpellier], Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Cellules Souches, Plasticité Cellulaire, Médecine Régénératrice et Immunothérapies (IRMB), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Department of Biology [Utah], University of Utah, Laboratoire Evolution, Génomes et Spéciation (LEGS), Centre National de la Recherche Scientifique (CNRS), Hôpital Côte de Nacre [CHU Caen], CHU Caen, Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN)-Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN), Service de biochimie [CHU Caen], Signalisation, électrophysiologie et imagerie des lésions d’ischémie-reperfusion myocardique (SEILIRM), Département Génétique Médicale-Maternité, Université de Lorraine (UL), Center for Medical Genetics, Centre de Recherche Jean-Pierre AUBERT Neurosciences et Cancer - U1172 Inserm - U837 (JPArc), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Lille Nord de France (COMUE)-Université de Lille, Department of Human Genetics, Radboud University Medical Center [Nijmegen], AI-lab, Vakgroep Computerwetenschappen, Universiteit Gent [Ghent], gerard, marion, Università degli studi di Torino = University of Turin (UNITO), Universiteit Gent = Ghent University (UGENT), and Informatics and Applied Informatics
- Subjects
Male ,0301 basic medicine ,Guanylate Kinases/genetics ,Developmental Disabilities ,Intellectual disability ,lcsh:Medicine ,ASPM ,brain imaging ,brain development ,Tumor Suppressor Proteins -- genetics ,Genome ,Mice ,Intellectual Disability -- genetics -- metabolism ,Global developmental delay ,Copy-number variation ,Promoter Regions, Genetic ,Child ,Genetics (clinical) ,Epigenomics ,Genetics ,ATP6 deletion ,Membrane Proteins -- genetics ,primary microcephaly ,Neurodevelopmental disorders ,food and beverages ,Functional genomics ,Exons ,DLG2 ,Promoters ,Animals ,Female ,Guanylate Kinases ,Humans ,Intellectual Disability ,Membrane Proteins ,Tumor Suppressor Proteins ,Molecular Medicine ,Molecular Biology ,Sciences bio-médicales et agricoles ,[SDV.BBM.GTP] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN] ,Guanylate Kinases -- genetics ,lcsh:QH426-470 ,Developmental Disabilities/genetics ,Developmental Disabilities/metabolism ,Intellectual Disability/genetics ,Intellectual Disability/metabolism ,Membrane Proteins/genetics ,Tumor Suppressor Proteins/genetics ,Genomics ,[SDV.GEN.GH] Life Sciences [q-bio]/Genetics/Human genetics ,Biology ,Promoter Regions ,03 medical and health sciences ,Genetic ,Complex V deficiency ,Next generation sequencing ,[SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN] ,Gene ,MCPH ,Developmental Disabilities -- genetics -- metabolism ,Research ,lcsh:R ,Human genetics ,Mitochondrial disease ,lcsh:Genetics ,030104 developmental biology ,centrosome ,[SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics ,NARP syndrome - Abstract
Tissue-specific integrative omics has the potential to reveal new genic elements important for developmental disorders., SCOPUS: ar.j, info:eu-repo/semantics/published
- Published
- 2017
15. The management of acute venous thromboembolism in clinical practice. Results from the European PREFER in VTE Registry
- Author
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Cohen, At, Gitt, Ak, Bauersachs, R, Fronk, Em, Laeis, P, Mismetti, P, Monreal, M, Willich, Sn, Bramlage, P, Agnelli, G, Brodmann, M, Rief, P, Eischer, L, Stoshikj, S, Hirschl, M, Weinmann, S, Peter Marschang, P, Abbadie, F, Achkar, A, Addala, A, Reynaldo, P, Adnet, F, Alexandra, Jf, Aquilanti, S, Belhassane, A, Benaroya, B, Berremili, T, Grenot, Mc, Birr, V, Holtea, D, Bonnin, C, Bosler, F, Bresin Durand MG, Brisot, D, Brousse, C, De La Fuente, T, Cayman, C, Cazaubon, M, Champion, O, Chanut, M, Chevalet, P, Connault, J, Durant, C, Constans, J, Cordeanu, M, Couturaud, F, Lacut, K, De Dedker, L, Piloquet, Fx, Decoulx, E, Derrien, B, Diamand, Jm, Diard, A, Douadi, Y, Dupas, S, Modeliar Remond SS, Sevestre, Ma, Edhery, S, Falvo, N, Farcas Taralunga, C, Ferrari, E, Gaillard, C, Garrigues, D, Gillet, Jl, Giordana, P, Grange, C, Vital-Durand, D, Grare, F, Hadj Henni, A, Heuser, S, Schmidt, J, Hidden-Henic, V, Hottin, D, Imbert, B, Pernod, G, Jakob, D, Jacquinandi, V, Jurus, C, Lacoste, A, Laroche, Jp, Martin, M, Mazollier, C, Mersel, T, Miserey, G, Nedey, C, Nou, M, Quere, I, Ouvry, P, Peuch, B, Pichot, O, Poulain, V, Ray, P, Rifai, A, Roy, Pm, Saby, Jc, Simon, F, Simonot-Lalandec, E, Stephan, D, Tissot, A, Vodoungnon, H, Adamczyk, A, Schnabl, S, Al Ahmad, W, Weber, H, Axthelm, C, Axthelm, P, Bergmann, K, Beschorner, U, Knittel, M, Binias, Kh, Pasligh, M, Boral, M, Girke, F, Bratsch, H, Brauer, G, Burghard, S, Demann, C, Rennebaum, C, Emter, E, Demmig, A, Eberlein, U, Enger, F, Eschenburg, J, Eschenburg, Ju, Forkmann, L, Frank, J, Freischmidt, H, Gassauer, M, Fritsche, I, Kubicek–hofmann, C, Goebels, Mc, Guggenbichler, S, Härtel, D, Hartmann, K, Heilberger, P, Heinsius, A, Held, M, Schnupp, S, Herman, G, Herold, J, Hertrich, F, Hommel, H, Hütte, G, Kalka, C, Jungandreas, K, Ramthor, M, Karcher, J, Werner, N, Karl-Wollweber, S, Keilhau, Da, Kittel, K, Knolinski, T, Köhler, C, Werth, S, Kopplin, U, Körner, I, Wittig, K, Dres, P, Kröger, K, Moysidis, T, Kroschel, U, Leschke, M, zur Nieden, T, Lübbert, G, Lutz, A, Wucherpfennig, P, Marencke, Gh, Mortensen, K, Reppel, M, Nelles, H, Nestler, K, Neumeister, A, Schlosser, A, Oettler, W, Ott, I, Otto, A, Pertermann, A, Pfister, R, Pindur, P, Pourhassan, S, Predel, D, Pudollek, T, Reimer, D, Richter, R, Eberhad Rieker, E, Rothenbücher, G, Rothhagen, B, Rudolff, S, Stücker, M, Schäfer, A, Sonnenschein, K, Schafnitzl, W, Schellong, S, Voigts, B, Schiller, M, Schmeink, T, Schmeink, P, Schneider, H, Schön, N, Schulze, M, Sechtem, U, Sedl, S, Werno, Hs, Stachowitz, J, Thieme, M, Tiefenbacher, C, Tsantilas, D, Vieth, P, vom Dahl, J, Grün-Himmelmann, K, von Bilderling, P, von Maltik, T, Weinrich, K, Weyer, M, Wirtz, P, Wittig, I, Zierock, P, Ageno, W, Caprioli, C, Rancan, E, Guercini, F, Mommi, V, Amitrano, M, Cannavacciuolo, F, Amore, M, D'Antoni, S, Angelini, E, La Forgia, S, Antignani, Pl, Calandra, G, Arone, A, Perticone, F, Sciacqua, A, Asaro, G, Bellisi, M, Attanzio, Mt, Pinto, A, Attinasi, V, Cillari, E, Sorvillo, S, Balbarini, A, Santini, C, Violo, C, Banfi, E, Lodigiani, C, Barcellona, D, Delpin, S, Marongiu, S, Barillari, G, Pasca, S, Bartolini, C, Verdecchia, P, Bartone, M, Mancuso, G, Bellanuova, I, Felis, S, Bellizzi, A, Masotti, L, Bianchi, M, Carugati, A, Bianchini, G, Guarnera, G, Boari, B, Gallerani, M, Pasin, M, Bortoluzzi, C, Parisi, R, Brucoli, C, Palasciano, G, Camporese, G, Tonello, C, Canafoglia, L, Rupoli, S, Cancellieri, E, Paoletti, O, Testa, S, Carlizza, A, Carnovali, M, Sada, S, Samaden, A, Casarsa, C, Mearelli, F, Pivetti, G, Catalini, R, Zingaretti, O, Cavazza, S, Cosmi, B, Cenci, C, Prisco, D, Silvestri, E, Ceresa, F, Patanè, F, Ciampa, A, Siniscalchi, V, Ciarambino, T, De Bartolomeo, G, Clemente, M, Conti, F, Paiella, L, D’Avino, M, D'Alessandro, A, Placentino, M, Sollazzo, V, D'Angelo, A, Viganò, S, De Campora, P, Sangiuolo, R, De Franciscis, S, Serra, R, De Gaudenzi, E, De Santis, F, Piccinni, Gc, De Tommaso, I, Di Francesco, L, Vincentelli, Gm, Di Maggio, R, Saccullo, G, Siragusa, S, Di Micco, P, Fontanella, A, Di Michele, D, Di Minno, G, Tufano, A, Di Nisio, M, Porreca, E, Donadio, F, Imberti, D, Enea, I, Fabbian, F, Manfredini, R, Pala, P, Falanga, A, Milesi, V, Fiore, V, Signorelli, Ss, Franco, E, Giudice, G, Frausini, G, Rovinelli, M, Fuorlo, M, Landolfi, R, Morretti, T, Gamberini, S, Salmi, R, Ghirarduzzi, A, Ghizzi, G, Pepe, C, Gianniello, F, Martinelli, I, Iosub, Di, Piovella, F, Iozzi, E, Talerico, A, La Regina, M, Orlandini, F, Marconi, L, Palla, A, Marcucci, R, Poli, D, Margheriti, R, Sala, G, Marra, A, Marrocco, F, Montagna, Es, Silvestris, F, Vallarelli, S, Mos, L, Rossetto, V, Mugno, F, Di Salvo, M, Nitti, C, Pennacchioni, M, Salvi, A, Olivieri, O, Tosi, F, Zorzi, F, Onesta, M, Pagliara, V, Villalta, S, Paolucci, G, Severino, S, Pierri, F, Russo, V, Pizzini, Am, Quintavalla, R, Rubino, P, Ria, L, Schenone, A, Strafino, C, Tropeano, P, Vetrano, V, Zanatta, N, Adarraga Cansino MD, Gutierrez, Ja, de las Revillas FA, Amado Fernández, C, Calvo Mijares, N, Blanco-Molina, Ma, Garcia, Ma, Joya Seijo, D, Aranda Blazquez, R, López-Sáez, Jb, Arellano Rodrigo, E, Villalta Blanch, J, Armengou Arxe, A, García-Bragado Dalmau, F, Ballaz Quincoces, A, García Loizaga, A, Beato Pérez JL, Bedate Díaz, P, Quezada Loaiza, A, Castellote, Mc, Cañas Alcántara, I, Lluís Padierna, M, Carrasco Expósito, M, Millón Caño JA, Carrasco Mas, A, Cereto Castro, F, Castrodeza Sanz, R, Ortiz de Saracho, J, Cisneros de la Fuente, E, de Ancos Aracil, C, Ruiz, J, de Daborenea González MD, Fernández Iglesias, A, de la Fuente Aguado, J, González, Lg, del Carmen Fernández-Capitán, M, Lorenzo Hernández, A, del Toro Cervera, J, Pérez Rus, G, Delgado Bregel JL, Díez Fernández, F, Santalla Valle EA, Elias Hernández, T, Jara Palomares, L, Ferri Bataler, R, Nieto Rodríguez JA, García García JM, Villanueva Montes MA, González Porras JR, Guil García, M, San Román Terán CM, Hernando López, E, Roncero Lázaro, A, Jaras, Mj, Jiménez Castro, D, Jiménez-Rodríguez Madridejos, R, Pedrajas Navas JM, Lecumberri, R, Martínez, N, López Castellanos GT, Manzano Espinosa, L, López Jiménez, L, Madridano Cobo, O, Mainez Saiz, C, Romero Pizarro, Y, Marchena Yglesias PJ, Martín del Pozo, M, Melibovsky, L, Altarriba, Es, Monreal Bosch, M, Monte Secades, R, Mora Luján JM, Riera Mestre, A, Moral Moral, P, Todolí Parra JA, Moreno Flores, A, Sánchez Muñoz-Torrero JF, Muñoz Rodríguez FJ, Núñez Fernández MJ, Oncala Sibajas, E, Vaquero de Sedas, M, Parra Caballero, P, Pons Martín del Campo, I, Portillo Sánchez, J, Rivera Gallego, A, Villaverde Álvarez, I, Rodríguez Beltrán EM, Sánchez Fuentes, D, Roldán Schilling, V, Sánchez Álvarez, J, López, Gt, Suriñach Caralt JM, Tirado Miranda, R, Usandizaga de Antonio, E, Banyai, M, Frank, U, Jörg, Gr, Jeanneret, C, Staub, D, Ackroyd, A, Agarwal, G, Mearns, B, Alikhan, R, Allameddine, A, Al-Refaie, F, Arden, C, Austin, A, Bakhai, A, Barton, T, Ewad, H, Body, R, Thachil, J, Chacko, J, Chandra, D, Charters, F, Church, A, Mcgrane, F, Clements, J, Clifford, P, Cox, D, Crouch, M, Crowther, M, Davies, E, Davies, M, Dimitri, S, Drebes, A, Franklin, S, George, J, Irvine, N, Gerofke, H, Gibbs, C, Goh, T, Gupta, S, Holmes, J, Jackson-Voyzey, E, Jones, N, Kallat, A, Kerr, P, Kesteven, P, Lench, T, Lester, W, Lowe, G, Lewis, M, Mccormack, T, Mccoye, A, Moriarty, A, Morris, W, Narayanan, M, Oo, N, Reed, M, Rose, P, Saja, K, Sivakumaran, M, Sohal, M, Solomons, G, Sultanzadeh, Sj, Venton, T, Wakeling, J, Walby, C, Waldron, M, Watt, S, Willcock, W, and Zafar, A.
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Male ,Time Factors ,Databases, Factual ,Administration, Oral ,Disease ,Comorbidity ,030204 cardiovascular system & hematology ,registry ,Direct oral anticoagulants ,0302 clinical medicine ,Recurrence ,Risk Factors ,Epidemiology ,030212 general & internal medicine ,Prospective Studies ,Registries ,anticoagulation ,LS4_7 ,Venous Thrombosis ,Hematology ,Venous Thromboembolism ,Vitamin K antagonist ,Middle Aged ,Thrombosis ,Pulmonary embolism ,Europe ,vitamin K antagonists ,Treatment Outcome ,Administration ,Female ,Coagulation and Fibrinolysis ,Venous thromboembolism ,Oral ,Adult ,medicine.medical_specialty ,Registry ,medicine.drug_class ,Socio-culturale ,Hemorrhage ,direct oral anticoagulants ,Venous thromboembolism, anticoagulation, direct oral anticoagulants, registry, vitamin K antagonists ,Anticoagulation ,Vitamin K antagonists ,Aged ,Anticoagulants ,Humans ,Pulmonary Embolism ,03 medical and health sciences ,Databases ,Disease registry ,Internal medicine ,medicine ,cardiovascular diseases ,Intensive care medicine ,Factual ,business.industry ,medicine.disease ,equipment and supplies ,Clinical trial ,business - Abstract
SummaryVenous thromboembolism (VTE) is a significant cause of morbidity and mortality in Europe. Data from real-world registries are necessary, as clinical trials do not represent the full spectrum of VTE patients seen in clinical practice. We aimed to document the epidemiology, management and outcomes of VTE using data from a large, observational database. PREFER in VTE was an international, non-interventional disease registry conducted between January 2013 and July 2015 in primary and secondary care across seven European countries. Consecutive patients with acute VTE were documented and followed up over 12 months. PREFER in VTE included 3,455 patients with a mean age of 60.8 ± 17.0 years. Overall, 53.0% were male. The majority of patients were assessed in the hospital setting as inpatients or outpatients (78.5%). The diagnosis was deep-vein thrombosis (DVT) in 59.5% and pulmonary embolism (PE) in 40.5%. The most common comorbidities were the various types of cardiovascular disease (excluding hypertension; 45.5%), hypertension (42.3%) and dyslipidaemia (21.1%). Following the index VTE, a large proportion of patients received initial therapy with heparin (73.2%), almost half received a vitamin K antagonist (48.7%) and nearly a quarter received a DOAC (24.5%). Almost a quarter of all presentations were for recurrent VTE, with >80% of previous episodes having occurred more than 12 months prior to baseline. In conclusion, PREFER in VTE has provided contemporary insights into VTE patients and their real-world management, including their baseline characteristics, risk factors, disease history, symptoms and signs, initial therapy and outcomes.
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- 2016
16. Genetic interactions between the parasitoid wasp Leptopilina boulardi and its Drosophila hosts
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Dubuffet, A., Dupas, S., Frey, F., Drezen, J-M., Poirie, M., and Carton, Y.
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Drosophila -- Genetic aspects ,Host-parasite relationships -- Genetic aspects ,Biological sciences - Abstract
Genetic variation in resistance of Drosophila yakuba to the parasitoid wasp Leptopilina boulardi is described. It is demonstrated that there are different resistance patterns to the parasitoid species L. boulardi in D. melanogaster and D. yakuba and different specificity levels in the parasitoid species, which suggests complex ecological interactions in the field.
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- 2007
17. Genetic dimension of the coevolution of virulence-resistance in Drosophila-parasitoid wasp relationships
- Author
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Dupas, S., Carton, Y., and Poirie, M.
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Heredity -- Research ,Heredity -- Genetic aspects ,Host-parasite relationships -- Genetic aspects ,Host-parasite relationships -- Research ,Drosophila -- Genetic aspects ,Evolution -- Genetic aspects ,Pathogenic microorganisms -- Genetic aspects ,Wasps -- Genetic aspects ,Biogeography -- Research ,Biological sciences - Abstract
Research has been conducted on variations in parasite virulence and host resistance. The studies of host-parasitoid system demonstrate that the geographical variations of traits are subjected to antaginistic selection governed by variations, and that the main parameter accounting for these geographic variations is the host species number.
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- 2003
18. Is genome size of Lepidoptera linked to host plant range?
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Calatayud, P.-A., primary, Petit, C., additional, Burlet, N., additional, Dupas, S., additional, Glaser, N., additional, Capdevielle-Dulac, C., additional, Le Ru, B., additional, Jacquin-Joly, E., additional, Kaiser-Arnauld, L., additional, Harry, M., additional, and Vieira, C., additional
- Published
- 2016
- Full Text
- View/download PDF
19. Quelques exemples de bio-invasions dans le monde
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Vidal, Claire, Gauthier, Nathalie, Rochat, D., Hérard, F., Thiéry, A., Vayssières, J.F., Dupas, S., Dangles, Olivier, Silvain, Jean-François, Torres-Leguizamon, Magally, Zeddam, Jean-Louis, Sforza, R., Desneux, N., Institut de Recherche pour le Développement (IRD), Physiologie de l'Insecte : Signalisation et Communication (PISC), Institut National de la Recherche Agronomique (INRA)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National Agronomique Paris-Grignon (INA P-G), European Biological Control Laboratory (EBCL), United States Department of Agriculture (USDA), Université de la Méditerranée - Aix-Marseille 2, Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad), Universidad Mayor de San Andrés (UMSA), UMR - Interactions Plantes Microorganismes Environnement (UMR IPME), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Université de Montpellier (UM)-Institut de Recherche pour le Développement (IRD [France-Sud]), Institut Sophia Agrobiotech (ISA), Centre National de la Recherche Scientifique (CNRS)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut National de la Recherche Agronomique (INRA), Nicolas Sauvion (ed. scient.),Paul-André calatayud (ed. scient.), Denis thiéry (ed. scient.), Frédéric Marion-Poll (ed. scient.), Institut National de la Recherche Agronomique (INRA)-Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Centre National de la Recherche Scientifique (CNRS), Sauvion, N. (ed.), Calatayud, Paul-André (ed.), Thiéry, D. (ed.), and Marion-Pol, F. (ed.)
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Glycine max ,Platanus occidentalis ,INVASION ,Relation plante animal ,éradication ,TAXONOMIE ,Bemisia tabaci ,PHYTOPHAGE ,Interactions biologiques ,Plante légumière ,Coccoidea ,Cerambycidae ,Dynamique des populations ,ADAPTATION ,Anoplophora glabripennis ,bio invasion ,Introduction d'animaux ,Lutte antiravageur ,Ravageur des plantes ,LEPIDOPTERE RAVAGEUR ,PIEGEAGE ,RESISTANCE DE L'HOTE ,Tephritidae ,INTRODUCTION D'ESPECES ,HISTOIRE ,PRATIQUE CULTURALE ,Gelechiidae ,INSECTE ,espèces introduites ,Feuillu ,Cicadellidae ,[SDV.OT]Life Sciences [q-bio]/Other [q-bio.OT] ,Anoplophora chinensis ,BIOTYPE ,monde ,Plante fruitière ,ECHANGE COMMERCIAL ,Corythucha ,Rhynchophorus ferrugineus ,METHODE DE LUTTE ,Araceae ,LUTTE BIOLOGIQUE ,Solanum tuberosum ,Nicotiana tabacum ,VECTEUR ,SUCCES INVASIF ,Étude de cas ,INFESTATION ,INVASION BIOLOGIQUE ,DIVERSITE GENETIQUE ,H10 - Ravageurs des plantes ,Lutte biologique ,analyses des risques ,PLANTE HOTE ,méthode de lutte ,CHANGEMENT CLIMATIQUE ,Écologie animale ,Aphis glycines ,Plante de culture ,REPARTITION GEOGRAPHIQUE ,Espèce envahissante - Abstract
chapitre 3; National audience
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- 2013
20. Faisabilité des procédures d’ablation endoveineuse de la grande veine saphène par radiofréquence en ambulatoire à l’hôpital
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Dupas, S., primary, Gaillard, C., additional, Frigul, B., additional, Avisse, A., additional, and Sevestre-Pietri, M.A., additional
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- 2014
- Full Text
- View/download PDF
21. Variation of Leptopilina boulardi success in Drosophila hosts : What is inside the Black Box ?
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Dubuffet, A., Colinet, D., Anselme, C., Dupas, S., Carton, Y., Poirie, M., Laboratoire Evolution, Génomes et Spéciation (LEGS), Centre National de la Recherche Scientifique (CNRS), Institute of Integrative and Comparative Biology, Faculty of Biological Sciences, University of Leeds, Interactions Biotiques et Santé Végétale, Institut National de la Recherche Agronomique (INRA), UR 072, Laboratoire Evolution, Génomes et Spéciation, Institut de Recherche pour le Développement (IRD), Pontificia Universidad Católica del Ecuador, and Simonneau, Evelyne
- Subjects
[SDV.BA] Life Sciences [q-bio]/Animal biology ,[SDV]Life Sciences [q-bio] ,[SDV.BA]Life Sciences [q-bio]/Animal biology ,fungi ,ComputingMilieux_MISCELLANEOUS ,RELATION HOTE-PARASITE - Abstract
International audience; Interactions between Drosophila hosts and parasitoid wasps are among the few examples in which occurrence of intraspecific variation of parasite success has been studied in natural populations. Such variations can originate from three categories of factors: environmental, host and parasitoid factors. Under controlled laboratory conditions, it is possible to focus on the two last categories, and, using specific reference lines, to analyze their respective importance. Parasitoid and host contributions to variations in parasite success have largely been studied in terms of evolutionary and mechanistic aspects in two Drosophila parasitoids, Asobara tabida and, in more details, in Leptopilina boulardi. This chapter focuses on the physiological and molecular aspects of L. boulardi interactions with two Drosophila host species, while most of the evolutionary hypotheses and models are presented in Chapter 11 of Dupas et al.
- Published
- 2009
22. Local, geographic and phylogenetic scales of coevolution in Drosophila-Parasitoid interactions
- Author
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Dupas, S., Dubuffet, Aurore, Carton, Yves, Poirie, Marylene, UR 072, Laboratoire Evolution, Génomes et Spéciation, Institut de Recherche pour le Développement (IRD), Pontificia Universidad Católica del Ecuador, Institute of Integrative and Comparative Biology, Faculty of Biological Sciences, University of Leeds, Interactions Biotiques et Santé Végétale, and Institut National de la Recherche Agronomique (INRA)
- Subjects
DROSOPHILA PARASITOIDS ,COEOLUTIONARY DIVERSIFICATION ,COEVOLUTIONARY ESCALATION ,[SDV]Life Sciences [q-bio] ,fungi ,CONSTRAINTS ,GEOGRAPHIC MOSAIC OF COEVOLUTION ,COEVOLUTIONARY POLYMORPHISM ,COEVOLUTIONARY ALTERNATION ,PHYLOGENETIC - Abstract
International audience; In this chapter, we describe the geographically widespread genetic fixation of traits involved in Drosophila–parasitoid immune interactions and the situations where such fixation is not observed. We then discuss how the three classes of coevolutionary dynamics that can occur at the local scale (coevolutionary escalation, coevolutionary alternation and coevolutionary polymorphism), the geographic mosaic of selection, and the phylogenetic constraints may explain such evolutionary patterns and drive diversification in the interactions. Most Drosophila parasitoid traits involved in virulence are host-species specific. Directional selection (coevolutionary escalation) on such traits can lead to their fixation or on the contrary maintain their polymorphism if these traits are associated with fitness costs. When hosts targeted by different host-specific virulence systems coexist, fluctuations in selective pressures on these systems, together with the ability of Drosophila parasitoids to select the most susceptible host for parasitization, can lead to coevolutionary alternation. Finally, we discuss the potential for parasitoid diversification in relation with the fact that most observed geographic situations, for different parasitoid clades, correspond to coevolutionary cold spots, due to fixation of virulence in parasitoid taxa.
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- 2009
23. Evolution of a polydnavirus gene in relation parasitoid host species immune resistance
- Author
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Dupas, S., C.W., Gitau, Branca, A., Ru B.P., Le, J.-F., Silvain, Laboratoire Evolution, Génomes et Spéciation (LEGS), Centre National de la Recherche Scientifique (CNRS), and Simonneau, Evelyne
- Subjects
[SDV.BA] Life Sciences [q-bio]/Animal biology ,[SDV.BA]Life Sciences [q-bio]/Animal biology - Published
- 2008
24. Viral cystatin evolution and 3D structure modelling a case of directional selection acting on a viral protein involved in a host-parasitoid interaction
- Author
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Serbielle, C., Chowdhury, S., Pichon, S., Dupas, S., Lesobre, J., E.O., Purisima, J.-M., Drezen, Huguet, E., Laboratoire Evolution, Génomes et Spéciation (LEGS), Centre National de la Recherche Scientifique (CNRS), and Simonneau, Evelyne
- Subjects
[SDV.BA] Life Sciences [q-bio]/Animal biology ,[SDV.BA]Life Sciences [q-bio]/Animal biology - Published
- 2008
25. Inferring from Cyt b gene the Triatoma brasiliensis Neiva, 1911 (Hemiptera : Reduviidae : Triatominae) genetic structure and domiciliary infestation in the state of Paraiba, Brazil
- Author
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Almeida, C., Pacheco, R., Haag, K., Dupas, S., Dotson, E., Costa, J., Laboratoire Evolution, Génomes et Spéciation (LEGS), Centre National de la Recherche Scientifique (CNRS), and Simonneau, Evelyne
- Subjects
[SDV.BA] Life Sciences [q-bio]/Animal biology ,[SDV.BA]Life Sciences [q-bio]/Animal biology - Published
- 2008
26. Diversity and abundance of wild host plants of lepidopteran stem borers in two agroecological zones of Kenya
- Author
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N.A., Otieno, Ru B., Le, G.O., Ong'Amo, Moyal, P., Dupas, S., P.-A., Calatayud, J.F., Silvain, Simonneau, Evelyne, Laboratoire Evolution, Génomes et Spéciation (LEGS), and Centre National de la Recherche Scientifique (CNRS)
- Subjects
[SDV.BA] Life Sciences [q-bio]/Animal biology ,[SDV.BA]Life Sciences [q-bio]/Animal biology - Published
- 2008
27. Genetic interactions between a parasitoid wasp and its Drosophila hosts
- Author
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Dubuffet, A., Dupas, S., Frey, F., Drezen, J.-M., Poirié, M., Carton, Y., Laboratoire Evolution, Génomes et Spéciation (LEGS), Centre National de la Recherche Scientifique (CNRS), and Simonneau, Evelyne
- Subjects
[SDV.BA] Life Sciences [q-bio]/Animal biology ,[SDV.BA]Life Sciences [q-bio]/Animal biology ,ComputingMilieux_MISCELLANEOUS - Abstract
International audience
- Published
- 2007
28. Differential expression of the CrV1 haemocyte inactivation-associated polydnavirus gene in the African maize stem borer Busseola fusca (Fuller) parasitized by two biotypes of the endoparasitoid Cotesia sesamiae (Cameron)
- Author
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C.W., Gitau, Gundersen-Rindal, D., Pedroni, M., P.J., Mbugi, Dupas, S., Simonneau, Evelyne, Laboratoire Evolution, Génomes et Spéciation (LEGS), and Centre National de la Recherche Scientifique (CNRS)
- Subjects
[SDV.BA] Life Sciences [q-bio]/Animal biology ,[SDV.BA]Life Sciences [q-bio]/Animal biology ,parasitic diseases ,fungi ,gene expression ,busseola fusca ,CrV1 genes ,Cotesia sesamiae ,ComputingMilieux_MISCELLANEOUS - Abstract
Polydnaviruses are rarely studied for their natural variation in immune suppressive abilities. The polydnavirus harboring braconid Cotesia sesamiae, a widespread endoparasitoid of Busseola fusca and Sesamia calamistis in sub-Saharan Africa exists as two biotypes. In Kenya, the western biotype completes development in B. fusca larvae. However, eggs of the coastal C sesamiae are encapsulated in this host and ultimately, no parasitoids emerge from parasitized B. fusca larvae. Both biotypes develop successfully in S. calamistis larvae. Encapsulation activity by B. fusca larvae towards eggs of the avirulent C sesamiae was detectable six hours post-parasitization. The differences in encapsulation of virulent and avirulent strains were associated with differences in nucleotide sequences and expression of a CrV1 polydnavirus (PDV) gene, which is associated with haemocyte inactivation in the Cotesia rubecula/Pieris rapae system. CrV1 expression was faint or absent in fat body and haemolymph samples from B. fusca parasitized by the avirulent C. sesamiae, which exhibited encapsulation of eggs. Expression was high in fat body and haernolymph samples from both B. fusca and S. calamistis larvae parasitized by the virulent C sesamiae, encapsulation in the former peaking at the same time points as CrV1 expression in the latter. Non synonymous difference in CrV1 gene sequences between virulent and avirulent wasp suggests that variations in B. fusca parasitism by C sesamiae may be due to qualitative differences in CrV1-haemocyte interactions.
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- 2007
29. Genome ecosystem and transposable elements species. *Gene*. 390: 214-220
- Author
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Le Rouzic, A., Dupas, S., Capy, P., Simonneau, Evelyne, Laboratoire Evolution, Génomes et Spéciation (LEGS), and Centre National de la Recherche Scientifique (CNRS)
- Subjects
[SDV.BA] Life Sciences [q-bio]/Animal biology ,[SDV.BA]Life Sciences [q-bio]/Animal biology - Published
- 2007
30. Distribution, pest status and agro-climatic preferences of lepidopteran stem borers of maize in Kenya
- Author
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Ong'Amo, G.O., Le Ru, B.P., Dupas, S., Calatayud, P.A., Silvain, J.-F., Laboratoire Evolution, Génomes et Spéciation (LEGS), Centre National de la Recherche Scientifique (CNRS), and Simonneau, Evelyne
- Subjects
[SDV.BA] Life Sciences [q-bio]/Animal biology ,[SDV.BA]Life Sciences [q-bio]/Animal biology - Published
- 2006
31. The role of wild grasses on densities of lepidopteran stemborer pests along altitudinal gradient in Kenya
- Author
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Ong'Amo, G. O., Le Ru, B., Dupas, S., Moyal, P., Muchugu, E., Calatayud, P. A., Silvain, J.-F., Simonneau, Evelyne, Laboratoire Evolution, Génomes et Spéciation (LEGS), and Centre National de la Recherche Scientifique (CNRS)
- Subjects
[SDV.BA] Life Sciences [q-bio]/Animal biology ,[SDV.BA]Life Sciences [q-bio]/Animal biology - Published
- 2006
32. The cereal stem borers of sub-Saharan Africa and their antagonists
- Author
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Dupas, S., Gitau, C., Le Rü, B., Silvain, J. -F, Calatayud, Paul-André (ed.), Le Rü, Bruno (ed.), Schulthess, F. (ed.), and Silvain, Jean-François (ed.)
- Subjects
IDENTIFICATION ,GRAMINEE VIVRIERE ,ESPECE ENDEMIQUE ,ELECTROPHORESE ,TECHNIQUE PCR ,TECHNIQUE RFLP ,FOREUR ,ANATOMIE ANIMALE ,CEREALE ,DIVERSITE SPECIFIQUE ,MARQUEUR MOLECULAIRE ,BIOLOGIE MOLECULAIRE ,TEST AMORCE SPECIFIQUE - Published
- 2006
33. Phylogeography and population genetics of the maize stalk borer Busseola fusca (Lepidoptera, Noctuidae) in sub-Saharan Africa
- Author
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Sezonlin, M., Dupas, S., Le Ru, B., Le Gall, P., Moyal, P., Calatayud, P.A., Giffard, I., Faure, N., Silvain, J.-F., Laboratoire Evolution, Génomes et Spéciation (LEGS), Centre National de la Recherche Scientifique (CNRS), and Simonneau, Evelyne
- Subjects
Pleistocene ,Busseola fusca ,[SDV.BA] Life Sciences [q-bio]/Animal biology ,[SDV.BA]Life Sciences [q-bio]/Animal biology ,population genetics ,African biogeography ,phylogeography - Abstract
The population genetics and phylogeography of African phytophagous insects have received little attention. Some, such as the maize stalk borer Busseola fusca, display significant geographic differences in ecological preferences that may be congruent with patterns of molecular variation. To test this, we collected 307 individuals of this species from maize and cultivated sorghum at 52 localities in West, Central and East Africa during the growing season. For all collected individuals, we sequenced a fragment of the mitochondrial cytochrome b. We tested hypotheses concerning the history and demographic structure of this species. Phylogenetic analyses and nested clade phylogeographic analyses (NCPA) separated the populations into three mitochondrial clades, one from West Africa, and two - Kenya I and Kenya II - from East and Central Africa. The similar nucleotide divergence between clades and nucleotide diversity within clades suggest that they became isolated at about the same time in three different refuges in sub-Saharan Africa and have similar demographic histories. The results of mismatch distribution analyses were consistent with the demographic expansion of these clades. Analysis of molecular variance (AMOVA) indicated a high level of geographic differentiation at different hierarchical levels. NCPA suggested that the observed distribution of haplotypes at several hierarchical levels within the three major clades is best accounted for by restricted gene flow with isolation by distance. The domestication of sorghum and the introduction of maize in Africa had no visible effect on the geographic patterns observed in the B. fusca mitochondrial genome.
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- 2006
34. The cereal stem borers of sub-Saharan Africa and their antagonists
- Author
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Gitau, C. W., Dupas, S., Ngi-Song, A. J., Mbugi, J. P., Schulthess, F., Calatayud, Paul-André (ed.), Le Rü, Bruno P. (ed.), Schulthess, F. (ed.), and Silvain, Jean-François (ed.)
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ELECTROPHORESE ,PROTEINE ,BIOTYPE ,ETUDE COMPARATIVE ,FOREUR ,VIRULENCE ,ENDOPARASITE ,LUTTE BIOLOGIQUE - Published
- 2006
35. High-NaCl Perception in Drosophila melanogaster
- Author
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Alves, G., primary, Salle, J., additional, Chaudy, S., additional, Dupas, S., additional, and Maniere, G., additional
- Published
- 2014
- Full Text
- View/download PDF
36. Phylogeography in continuous space: coupling species distribution models and circuit theory to assess the effect of contiguous migration at different climatic periods on genetic differentiation in Busseola fusca (Lepidoptera: Noctuidae)
- Author
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Dupas, S., primary, le Ru, B., additional, Branca, A., additional, Faure, N., additional, Gigot, G., additional, Campagne, P., additional, Sezonlin, M., additional, Ndemah, R., additional, Ong'amo, G., additional, Calatayud, P.‐A., additional, and Silvain, J.‐F., additional
- Published
- 2014
- Full Text
- View/download PDF
37. Trucs et astuces en écho-Doppler vasculaire
- Author
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Weber, L., primary, Barrellier, M.-T., additional, Baud, J.-M., additional, Böge, G., additional, Dauzat, M., additional, Dupas, S., additional, Gaillard, C., additional, Hamadé, A., additional, Laroche, J.-P., additional, and Sevestre-Pietri, M.-A., additional
- Published
- 2014
- Full Text
- View/download PDF
38. Incidence et facteurs de risque de la maladie thrombo-embolique veineuse dans le lymphome à grandes cellules
- Author
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Dupas, S., primary, Mane-Vandwalle, C., additional, Samy-Modeliar, S., additional, Royer, B., additional, Damaj, G., additional, Marolleau, J.-P., additional, and Sevestre, M.-A., additional
- Published
- 2012
- Full Text
- View/download PDF
39. Complications vasculaires des patients ayant bénéficié d’une ECMO (extracorporeal membrane oxygenation)
- Author
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Samy Modeliar, S., primary, Zogheib, E., additional, Kessavane, A., additional, Caminzuli, M., additional, Dupas, S., additional, Le Gloan, S., additional, Mardyla, M., additional, Allart, J.-D., additional, and Sevestre-Pietri, M.-A., additional
- Published
- 2011
- Full Text
- View/download PDF
40. Thromboses de l’aorte sous-rénale : prise en charge en 2011 ?
- Author
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Samy Modeliar, S., primary, Caminzuli, M., additional, Dupas, S., additional, Legloan, S., additional, Mardyla, M., additional, Allart, J.D., additional, Reix, T., additional, and Sevestre-Pietri, M.A., additional
- Published
- 2011
- Full Text
- View/download PDF
41. Diagnostics différentiels des malformations artério-veineuses périphériques ; à propos de 7 cas
- Author
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Le Gloan, S., primary, Allart, J.-D., additional, Caminzuli, M., additional, Devauchelle, B., additional, Dupas, S., additional, Samy-Modeliar, S., additional, Testelin, S., additional, and Sevestre-Pietri, M.-A., additional
- Published
- 2011
- Full Text
- View/download PDF
42. Suitability of cereal stemborers in Cameroon to Kenyan populations of the braconid larval parasitoid Cotesia sesamiae
- Author
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Ndemah, R., primary, Schulthess, F., additional, Abang, A., additional, Ghogomu, R. T., additional, Ntonifor, N., additional, Dupas, S., additional, and LeRü, B., additional
- Published
- 2010
- Full Text
- View/download PDF
43. Variability in the reproductive biology and in resistance against Cotesia sesamiae among two Busseola fusca populations
- Author
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Calatayud, P.-A., primary, Gitau, C., additional, Calatayud, S., additional, Dupas, S., additional, Le Ru, B., additional, and Silvain, J.-F., additional
- Published
- 2010
- Full Text
- View/download PDF
44. Wing shape variations in an invasive moth are related to sexual dimorphism and altitude
- Author
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Hernández-L., N., primary, Barragán, Á.R., additional, Dupas, S., additional, Silvain, J.-F., additional, and Dangles, O., additional
- Published
- 2010
- Full Text
- View/download PDF
45. Traitement des pseudo-anévrismes fémoraux postcathétérisation par injection périanévrismale de sérum salé
- Author
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Samy Modeliar, S., primary, Caminzuli, M., additional, Jarry, G., additional, Leborgne, L., additional, Dupas, S., additional, Reix, T., additional, and Sevestre-Pietri, M.-A., additional
- Published
- 2009
- Full Text
- View/download PDF
46. Thecis-regulatory sequences required for expression of theDrosophila melanogasteradult cuticle gene ACP65A
- Author
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Lestradet, M., primary, Gervasio, E., additional, Fraichard, S., additional, Dupas, S., additional, Alabouvette, J., additional, Lemoine, A., additional, and Charles, J. P., additional
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- 2009
- Full Text
- View/download PDF
47. Isolation and characterization of polymorphic microsatellites in the Potato Tuber Moth Tecia solanivora (Povolny, 1973) (Lepidoptera: Gelechiidae)
- Author
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TORRES‐LEGUIZAMON, M., primary, SOLIGNAC, M., additional, VAUTRIN, D., additional, CAPDEVIELLE‐DULAC, C., additional, DUPAS, S., additional, and SILVAIN, J.‐F., additional
- Published
- 2009
- Full Text
- View/download PDF
48. Species diversity of lepidopteran stem borer parasitoids in cultivated and natural habitats in Kenya
- Author
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Mailafiya, D. M., primary, Le Ru, B. P., additional, Kairu, E. W., additional, Calatayud, P.‐A., additional, and Dupas, S., additional
- Published
- 2009
- Full Text
- View/download PDF
49. Mesure transcutanée de la pression partielle d’oxygène : intérêt dans le pronostic et le suivi thérapeutique des patients en ischémie critique des membres inférieurs après thérapie cellulaire
- Author
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Solanilla, A., primary, Pignon, B., additional, Dupas, S., additional, Caminzuli, M., additional, Meziane, M., additional, Constans, J., additional, Reix, T., additional, and Sevestre-Pietre, M.-A., additional
- Published
- 2009
- Full Text
- View/download PDF
50. Diversite des filtres caves pour prevenir l’embolie pulmonaire. Traçabilite du dossier, interet de l’angiographie 3D
- Author
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Le Blanche, A., primary, Bouaziz, R., additional, Sevestre, M.A., additional, Dupas, S., additional, Dupont, H., additional, and Vallée, J.N., additional
- Published
- 2008
- Full Text
- View/download PDF
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