133 results on '"Dworetzky, Steven I."'
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2. Dexpramipexole as an oral steroid-sparing agent in hypereosinophilic syndromes
3. The targeted eosinophil-lowering effects of dexpramipexole in clinical studies
4. Effects of dexpramipexole on brain mitochondrial conductances and cellular bioenergetic efficiency
5. Cell Structure and the Regulation of Genes Controlling Proliferation and Differentiation: The Nuclear Matrix and Cytoskeleton
6. Translocation of RNA-Coated Gold Particles through the Nuclear Pores of Oocytes
7. The Effects of Variations in the Number and Sequence of Targeting Signals on Nuclear Uptake
8. Pharmacological activation and inhibition of Slack ( Slo2.2) channels
9. Targeting acute ischemic stroke with a calcium-sensitive opener of maxi-K potassium channels
10. Pharmacological activation and inhibition of Slack(Slo2.2) channels
11. A Thallium-Sensitive, Fluorescence-Based Assay for Detecting and Characterizing Potassium Channel Modulators in Mammalian Cells
12. The Pharmacology and Molecular Biology of Large-Conductance Calcium = Activated (BK) Potassium Channels
13. Microinjection of Colloidal Gold
14. Synthesis and biological evaluation of an iodinated iberiotoxin analogue, [mono-iodo-Tyr5, Phe36]-iberiotoxin
15. Dexpramipexole depletes blood and tissue eosinophils in nasal polyps with no change in polyp size
16. Dexpramipexole effectively lowers blood and tissue eosinophils in subjects with chronic rhinosinusitis with nasal polyps
17. Dexpramipexole depletes blood and tissue eosinophils in nasal polyps with no change in polyp size.
18. Discovery of (S,E)-3-(2-fluorophenyl)-N-(1-(3-(pyridin-3-yloxy)phenyl)ethyl)-acrylamide as a potent and efficacious KCNQ2 (Kv7.2) opener for the treatment of neuropathic pain
19. Discovery of a novel series of quinolone α7 nicotinic acetylcholine receptor agonists
20. JBS Special Issue: Innovative Screening Methodologies to Identify New Compounds for the Treatment of Central Nervous System Disorders
21. Neuronal Kv7 Potassium Channels as Emerging Targets for the Treatment of Pain
22. The Mitochondrial Complex V–Associated Large-Conductance Inner Membrane Current Is Regulated by Cyclosporine and Dexpramipexole
23. Decrease in a Leak Conductance Associated with Mitochondrial Complex V and Improved Bioenergetic Efficiency may Underlie Cytoprotection of at-Risk Neurons by Dexpramipexole
24. Synthesis and biological evaluation of an iodinated iberiotoxin analogue, [mono-iodo-Tyr5, Phe36]-iberiotoxin
25. Atropisomeric 3-(β-hydroxyethyl)-4-arylquinolin-2-ones as Maxi-K Potassium Channel Openers
26. 3-[(5-Chloro-2-hydroxyphenyl)methyl]-5-[4-(trifluoromethyl)phenyl ]-1,3,4-oxadiazol-2(3H)-one, BMS-191011: Opener of Large-Conductance Ca2+-Activated Potassium (Maxi-K) Channels, Identification, Solubility, and SAR
27. 3-Thio-quinolinone maxi-K openers for the treatment of erectile dysfunction
28. Synthesis and KCNQ2 opener activity of N-(1-benzo[1,3]dioxol-5-yl-ethyl, N-[1-(2,3-dihydro-benzofuran-5-yl)-ethyl, and N-[1-(2,3-dihydro-1H-indol-5-yl)-ethyl acrylamides
29. The Synthesis and Structure—Activity Relationships of 3-Amino-4-benzylquinolin-2-ones: Discovery of Novel KCNQ2 Channel Openers.
30. Synthesis and Structure−Activity Relationship of Acrylamides as KCNQ2 Potassium Channel Openers
31. The synthesis and structure–activity relationships of 3-amino-4-benzylquinolin-2-ones
32. (S)-N-[1-(4-Cyclopropylmethyl-3,4-dihydro-2H-benzooxazin-6-yl)-ethyl]-3-(2-fluoro-phenyl)-acrylamide is a potent and efficacious KCNQ2 opener which inhibits induced hyperexcitability of rat hippocampal neurons
33. Novel Openers of Ca2+-Dependent Large-Conductance Potassium Channels: Symmetrical Pharmacophore and Electrophysiological Evaluation of Bisphenols.
34. (S)-N-[1-(3-Morpholin-4-ylphenyl)ethyl]- 3-phenylacrylamide: An Orally Bioavailable KCNQ2 Opener with Significant Activity in a Cortical Spreading Depression Model of Migraine
35. 4-Aryl-3-(hydroxyalkyl)quinolin-2-ones: Novel Maxi-K Channel Opening Relaxants of Corporal Smooth Muscle Targeted for Erectile Dysfunction
36. 4,5-Diphenyltriazol-3-ones: Openers of Large-Conductance Ca2+-Activated Potassium (Maxi-K) Channels
37. The synthesis and characterization of BMS-204352 (MaxiPost™) and related 3-fluorooxindoles as openers of maxi-K potassium channels
38. Maxi-K Potassium Channels: Form, Function, and Modulation of a Class of Endogenous Regulators of Intracellular Calcium
39. ( S, E)- N-[1-(3-Heteroarylphenyl)ethyl]-3-(2-fluorophenyl)acrylamides: synthesis and KCNQ2 potassium channel opener activity
40. Formation of intermediate-conductance calcium-activated potassium channels by interaction of Slack and Slo subunits
41. DISCOVERY OF A NOVEL CLASS OF BK CHANNEL OPENERS: ENANTIOSPECIFIC SYNTHESIS AND BK CHANNEL OPENING ACTIVITY OF 3-(5-CHLORO-2-HYDROXYPHENYL)-1,3-DIHYDRO-3-HYDROXY-6-(TRIFLUOROMETHYL)-2H-INDOL-2-ONE
42. Differential expression of the α and β subunits of the large-conductance calcium-activated potassium channel: implication for channel diversity
43. The discovery of novel openers of Ca2+-dependent large-conductance potassium channels: Pharmacophore search and physiological evaluation of flavonoids
44. Phenotypic Alteration of a Human BK (hSlo) Channel byhSloβSubunit Coexpression: Changes in Blocker Sensitivity, Activation/Relaxation and Inactivation Kinetics, and Protein Kinase A Modulation
45. Modulators of Large-Conductance Calcium-Activated Potassium (BK) Channels as Potential Therapeutic Targets
46. N-Benzylated benzimidazol-2-one derivatives: activators of large-conductance Ca2+-dependent K+ channels
47. ( S)- N-[1-(4-Cyclopropylmethyl-3,4-dihydro-2 H-benzo [1,4]oxazin-6-yl)-ethyl]-3-(2-fluoro-phenyl)-acrylamide is a potent and efficacious KCNQ2 opener which inhibits induced hyperexcitability of rat hippocampal neurons
48. Synthesis and KCNQ2 opener activity of N-(1-benzo[1,3]dioxol-5-yl-ethyl, N-[1-(2,3-dihydro-benzofuran-5-yl)-ethyl, and N-[1-(2,3-dihydro-1 H-indol-5-yl)-ethyl acrylamides
49. Cloning and expression of a human large-conductance calcium-activated potassium channel
50. Regulation of transcription‐factor activity during growth and differentiation: Involvement of the nuclear matrix in concentration and localization of promoter binding proteins
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