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1. Midventricular obstruction and left ventricular remodeling after transcatheter aortic valve implantation

Author: Olga Moiseeva, E.V. Karelkina, P Murtazalieva, E Malev, D Zubarev, and D Zverev
Subjects: medicine.medical_specialty, business.industry, Hypertrophic cardiomyopathy, General Medicine, medicine.disease, Preoperative care, Muscle hypertrophy, medicine.anatomical_structure, Internal medicine, Aortic valve stenosis, Cardiology, Medicine, Radiology, Nuclear Medicine and imaging, Interventricular septum, Systole, Cardiology and Cardiovascular Medicine, business, Ventricular remodeling, Papillary muscle
Abstract: Funding Acknowledgements Type of funding sources: Foundation. Main funding source(s): Grant of Russian Foundation for Basic Research Introduction Long existing pressure overload results in left ventricular (LV) hypertrophy in severe aortic stenosis (AS). Post-TAVI left ventricular remodeling after relief of the high-pressure overload could lead to manifestation of postprocedural midventricular obstruction caused mostly by marked LV wall hypertrophy with the interposition of the hypertrophic papillary muscle in small LV chamber. Our aim was to evaluate the incidence and predictors of midventricular obstruction during 1-year follow-up in patients with AS who underwent transcatheter aortic valve implantation. Methods 30 consecutive patients (mean age: 82.3 ± 5.6 years) with symptomatic severe AS who underwent TAVI in 2018-2019 in Almazov centre and survived >12 months were enrolled in our observational, prospective, single-center study. Evolut R and Sapien-XT valves were used. All patients underwent transthoracic echocardiography before TAVI and at 3, 6, and 12 months after the procedure. There were no patients with baseline midventricular obstruction or concomitant hypertrophic obstructive cardiomyopathy. Results Procedure was successful in all cases. During 1 year of follow-up after TAVI, 3 patients (10%) demonstrated postprocedural midventricular obstruction with peak gradient – 36,3 ± 24,3 mm Hg. There was no difference in prosthetic diameter between obstructive and non-obstructive patients (27.0 ± 3,4 vs. 27.7 ± 5,1 mm, p = 0.85 - nonparametric Mann-Whitney U test for all comparisons). At baseline echocardiography, patients with midventricular obstruction had a significantly thicker interventricular septum (14.7 ± 2.5 vs. 11.5 ± 1.6mm, p Reductions in LV mass index were more significant in non-obstructive patients (49.8 ± 27.3 vs. 15.3 ± 15.0 g/m2, p Midventricular obstruction peak gradient correlates strongly with preoperative relative wall thickness (rs=.73; p In the multiple regression analyses, preoperative relative wall thickness (p Conclusions 10% of patients during 1 year of follow-up after TAVI demonstrate midventricular obstruction of various severity with poor reverse LV remodeling. Patients with a small hypertrophic left ventricle and high preoperative relative wall thickness, are at greater risk of development of the postprocedural midventricular obstruction.
Published: 2021
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2. The influence of afterload on left ventricular contractility: 2D-strain and dyssynchrony in stress echocardiography

Author: S Verbilo, E Malev, A Suvorov, E Karev, and M Prokudina
Subjects: medicine.medical_specialty, Ejection fraction, Longitudinal strain, business.industry, General Medicine, Left ventricular contractility, Blood pressure, Afterload, Internal medicine, Stress Echocardiography, Cardiology, Medicine, Radiology, Nuclear Medicine and imaging, Systole, Cardiology and Cardiovascular Medicine, business, 2d strain
Abstract: Funding Acknowledgements Type of funding sources: None. Background Hypertensive response to exercise (HRE) has negative prognostic value but its impact on the left ventricle (LV) contractility and on stress echocardiography (SE) results remains controversial. The global longitudinal strain (GLS) and LV dyssynchrony changes in response to afterload increase were shown even in patients with narrow QRS at rest, but not on exertion. Purpose We aimed to analyze the relation between the blood pressure (BP) during SE and LV GLS and dyssynchrony changes. Methods We performed exercise SE on treadmill in 96 patients without coronary artery stenosis (invasive or CT coronary angiography). Patients divided into two groups: HRE (n = 41) and normal response to exercise (NRE) (n = 55). We analyzed GLS and standard deviation of time between the onset of QRS and segmental longitudinal strain peaks (STE-TIME SD) using speckle tracking and 3d-ejection fraction (EF) at rest and on exertion. Results 2D-EF increase was higher in patients with NRE, but 3D-EF did not differ between groups. Wall motion abnormalities (WMA) on peak stress were detected more often in patients with HRE who had higher wall motion score index (WMSI). GLS on exertion and its increment were lower in HRE group (Fig. 1 - "Bull’s eye" diagrams of GLS at rest and on exertion in patient with NRE (upper panel) and HRE (lower panel)). Among dyssynchrony markers we revealed higher values of STE-TIME SD on exertion in HRE group (Table 1). Moreover the analysis showed positive correlations between BP level on exertion and peak GLS (r = 0.56, p Conclusions HRE is associated with less increment in GLS and 2D-EF on exertion. Besides LV dyssynchrony signs can appear in response to exaggerated afterload increase even in patients with narrow QRS complexes. Patients with HRE more often show stress-induced WMA and have greater WMSI on exertion in absence of coronary artery lesions, thus HRE can alter the specificity of the test in transient ischemia detection. Table 1 HRE NRE p Δ-2D ejection fraction 5.0 (4.0; 7.0) 10.0 (8.0; 12.5)
Published: 2021
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3. Global longitudinal strain and left ventricle dyssynchrony changes during stress echocardiography in response to antihypertensive treatment optimization

Author: E Karev, A Suvorov, S Verbilo, E Malev, and M Prokudina
Subjects: Coronary angiography, medicine.medical_specialty, Longitudinal strain, business.industry, Coronary arteriosclerosis, General Medicine, Narrow QRS complex, medicine.anatomical_structure, Bruce protocol, Blood pressure, Ventricle, Internal medicine, medicine, Stress Echocardiography, Cardiology, Radiology, Nuclear Medicine and imaging, Cardiology and Cardiovascular Medicine, business
Abstract: Funding Acknowledgements Type of funding sources: None. Background. The positive effect of blood pressure (BP) lowering medications on global longitudinal strain (GLS) and left ventricle (LV) dyssynchrony even in patients with narrow QRS complexes at rest has been established at rest. The dynamic changes of GLS and dyssynchrony markers on exertion are still remain underinvestigated, especially in patients with hypertensive response to exercise (HRE). Purpose. The aim of the study was to define if any changes in GLS and dyssynchrony markers assessed during exercise stress echocardiography (SE) can occur after the optimization of antihypertensive treatment. Methods. 18 patients without coronary artery stenosis on coronary angiography, underwent exercise SE on treadmill. All patients had arterial hypertension and HRE, defined as elevation of systolic BP ≥190 mmHg in women and ≥210 mmHg in men or ≥180 mmHg from the second stage of standard Bruce protocol. After optimization of BP lowering medications (addition/dose correction of ACEI/ARB, CCB or diuretics) we repeated SE within 138.5 ± 85.1 days. GLS and dyssynchrony markers at rest and on exertion from both tests were subsequently analyzed with the QLab and 3D-Q Advanced software. Results. The target systolic BP at rest was reached in all 18 patients (145.8 ± 21.8 mmHg vs. 126.1 ± 14.5 mmHg, p = 0.03), moreover exercise BP on exercise decreased significantly (209.4 ± 15.4 mmHg vs. 170.8 ± 14.4 mmHg, p = 0.003). We observed improvement in tolerance to exertion (7.2 ± 2.4 METs vs. 8.7 ± 3.0 METs, p = 0.0004), 2D and 3D-ejection fraction increase (4.7 ± 2.2% vs. 8.8 ± 2.1%, p = 0.0002 and 3.9 ± 4.9% vs. 10.8 ± 8.5, p = 0.03) and significant reduction of wall motion score index (1.21 ± 0.24 vs. 1.03 ± 0.11, p = 0.001). The speckle tracking analysis revealed increase in GLS on exertion (-20.4 ± 3.5 vs. -23.78 ± 3.2, p = 0.001) and its increment (-0.28 ± 2.1 vs. 3.17 ± 1.89, p = 0.0006), while the level of rest GLS remained unchanged (-20.61 ± 2.9 vs. -20.61 ± 2.6, p = 0.9) (Fig. 1). The dyssynchrony marker STE-TIME SD-IMPOST (standard deviation of time from QRS onset to peak segmental longitudinal strain on exertion) has also diminished (47.3 ± 18.4 vs. 33.8 ± 12.2, p = 0.005). Conclusions. Stress-induced wall motion abnormalities and poor increase/decrease in GLS observed in patients with HRE even in absence of coronary artery stenosis can resolve or diminish after antihypertensive treatment optimization. Speckle tracking LV-dyssynchrony markers in patients with narrow QRS complexes can also decrease in response to BP-lowering medications. Abstract Figure 1.
Published: 2021
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4. P5578Integrated approach in assessment of valvular calcification activity in aortic stenosis

Author: E Malev, E Zhiduleva, Olga Irtyuga, P Murtazalieva, D Ryzhkova, and Olga Moiseeva
Subjects: medicine.medical_specialty, Stenosis, Valvular calcification, business.industry, Internal medicine, Cardiology, Medicine, Cardiology and Cardiovascular Medicine, business, medicine.disease
Abstract: Introduction Calcification is the key pathological process in aortic stenosis (AS) development. Circulating biomarkers and nuclear imaging methods could characterize the valvular calcification activity. Purpose To compare diagnostic values of serum fetiun A level and PET/CT with 18F NaF in assessment of aortic valve calcification. Methods 88 pts with asymptomatic AS were included: 39pts with tricuspid aortic valve (TAV) and 49 pts with bicuspid aortic valve (BAV). ECHO was performed at baseline and in 16.6±4.2 months. At start serum level of fetuin A was measured by ELlSA in all pts and PET/CT with 18F NaF was performed in 60 of these pts (29 TAV pts and 31 BAV pts). Maximum standardized uptake value (SUV) was measured within circular region of interest (ROI) of 3.52 square millimeters that was drawn around areas of maximal 18F-NaF uptake in the valve. Blood-pool activity was estimated using maximum SUV within the same ROI, which was drawn on the left atrium. Ratio between maximum tissue and background SUV (TBR) was calculated. CT calcium scoring was performed using dedicated software. Results Pts with TAV were significantly older then BAV pts (62.4±5.3 yrs vs 55.9±8.4 yrs, p=0.003). TAV and BAV groups were comparable in AS severity by ECHO (peak aortic jet velocity (Vmax): 3.1±0.6 m/s vs 3.1±0.7 m/s, p=0.72). Both groups did not differ in valvular calcification degree (Agatston score 1433.9±1327.9 vs 1617.7±1404.5, p=0.59) and 18F-NaF uptake level (TBR 1.6±0.3 vs 1.6±0.5, p=0.64). Agatston score and TBR max 18F NaF were associated with AS severity measured by Vmax (r=0.58; p Conclusions Despite comparable valve calcification activity measured by PET/CT with 18F NaF in TAV and BAV pts, decreased circulating fetuin A was observed only in BAV pts, that may be related to different underlying pathophysiological mechanisms. Low serum fetuin-A level was associated with progression of AS, particularly in BAV pts. Acknowledgement/Funding Grant of Russian Foundation for Basic Research No. 18-015-00016
Published: 2019
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5. P4483Transforming growth factor-beta and arrhythmias in mitral valve prolapse patients

Author: L Vasina, M Gordeev, E. Malev, B Bondarenko, E. Zemtsovsky, Lubov Mitrofanova, M Omelchenko, and I Pankova
Subjects: medicine.medical_specialty, business.industry, Internal medicine, Growth factor, medicine.medical_treatment, medicine, Cardiology, Mitral valve prolapse, Cardiology and Cardiovascular Medicine, medicine.disease, business, Beta (finance)
Abstract: Transforming growth factor-β (TGF-β) is a multifunctional cytokine with fibrogenic properties. Also increased TGF-β signaling contributes to the development of myxomatous changes of the mitral valve (MV). Recent data suggests that TGF-β may play a potentially important role in the heart arrhythmogenesis. Our aim was to evaluate the possible proarrhythmic effects of TGF-β in patients with mitral valve prolapse (MVP) and severe mitral regurgitation (MR) undergoing MV repair. Methods 30 consecutive patients (mean age 53.1±9.4, 47% male) undergoing MV repair for severe MR due to MVP were enrolled in our observational, prospective, single-center study. Immunohistochemical characterization of mitral valve sections was performed with TGF-β1 and TGF-β2 primary antibodies. The levels of TGF-β1 and TGF-β2 in serum were determined by enzyme-linked immunosorbent assay Human Platinum ELISA.Transthoracic echocardiography and 24-hour Holter monitoring were performed pre- and postoperatively annually. Atrial fibrillation, PVCs and nonsustained ventricular tachycardia (VT) runs were reviewed. Results Resected MV leaflets showed the increase ofTGF-β1 and TGF-β2 positive cell count (33% and 38%, respectively). High level of TGF-β1 (>14.75 ng/ml) and/or TGF-β2 (>2.0 ng/ml) was detected in majority (77%) of patients and associated with thickening of posterior leaflet (r=0.67; p=0.016), residual valve prolapse (r=0.68; p=0.007) and recurrent MR (r=0.56; p=0.01), pre- and postoperative left atrial (p Atrial fibrillation was documented in 20% patients before repair. Postoperative AF occurred in 17% and associates with postoperative left atrial diameter (rs=0.60; p=0.008) and MR degree (rs=0.51; p=0.01). Total number of PVCs and non-sustained ventricular tachycardia runs dropped significantly in 1st (p=0.04, Wilcoxon matched pairs test) and 2nd (p=0.03), years of postoperative follow-up. Postoperative incidence of PVCs and VT associates strongly with postoperative end-diastolic LV diameter (rs=0.70; p=0.005), moderate negatively with LV ejection fraction (rs=−0.55; p=0.01). TGF-β2 (but not TGF-β1) serum level were associated with postoperative incidence of atrial fibrillation (p Conclusions High level of TGF-β2 is associated with persistent atrial (but not ventricular) arrhythmias in MVP patients after mitral valve repair, possibly through 1) progression of valve myxomatous after reconstructive surgery (via recurrent MR and LA enlargement) and 2) previously shown alteration of the electrophysiological phenotype of cardiac myofibroblasts.
Published: 2019
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6. P725Effect of renin-angiotensin system blockade in prevention of thoracic aortic aneurysm progression

Author: E. Malev, E. Zemtsovsky, E.B. Luneva, and Uspensky
Subjects: medicine.medical_specialty, Renin angiotensin system blockade, business.industry, Internal medicine, Renin–angiotensin system, Cardiology, Medicine, Cardiology and Cardiovascular Medicine, business, medicine.disease, Thoracic aortic aneurysm
Published: 2018
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7. 2462PET/CT with 18F-sodium fluoride in patients with aortic stenosis and different aortic valve morphology

Author: Olga Moiseeva, E Zhiduleva, S Kukushkina, E Malev, P Murtazalieva, D Ryzhkova, and Olga Irtyuga
Subjects: Aortic valve, medicine.medical_specialty, Morphology (linguistics), business.industry, medicine.disease, chemistry.chemical_compound, Stenosis, medicine.anatomical_structure, chemistry, Internal medicine, Sodium fluoride, Cardiology, Medicine, In patient, Cardiology and Cardiovascular Medicine, business
Published: 2018
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8. Poster session 2THE IMAGING EXAMINATIONP536Appropriate use criteria of transthoracic echocardiography and its clinical impact: a continuous challengeP537Implementation of proprietary plug-ins in the DICOM-based computerized echo reporting system fuels the use of 3D echo and deformation imaging in the clinical routine of a multivendor laboratoryP538Exercise stress echocardiography appropriate use criteria: real-life cases classification ease and agreement among cardiologistsANATOMY AND PHYSIOLOGY OF THE HEART AND GREAT VESSELSP539Functional capacity in older people with normal ejection fraction correlates with left ventricular functional reserve and carotid-femoral pulse wave velocity but not with E/e and augmentation indexP540Survey of competency of practitioners for diagnosis of acute cardiopulmonary diseases manifest on chest x-rayASSESSMENT OF DIAMETERS, VOLUMES AND MASSP541Left atrium remodeling in dialysis patients with normal ejection fractionP542The prediction of postinfarction left ventricular remodeling and the role of of leptin and MCP-1 in regard to the presence of metabolic syndromeP543Ascending aorta and common carotid artery: diameters and stiffness in a group of 584 healthy subjectsAssessments of haemodynamicsP544Alternate echo parameters in patients without estimable RVSPAssessment of systolic functionP545Reduced contractile performance in heart failure with preserved ejection fraction: determination using novel preload-adjusted maximal left ventricular ejection forceP546Left ventricular dimensions and prognosis in acute coronary syndromesP547Time course of myocardial alterations in a murine model of high fat diet: A strain rate imaging studyP548Subclinical left ventricular systolic dysfunction in patients with premature ventricular contractionsP549Global myocardial strain by CMR-based feature tracking (FT) and tagging to predict development of severe left ventricular systolic dysfunction after acute st-elevation myocardial infarctionP550Echocardiographic analysis of left and right ventricular function in patients after mitral valve reconstructionP551The role of regional longitudinal strain assessment in predicting response to cardiac resynchronization therapy in patients with left ventricular systolic dysfunction and left bundle branch blockP552Speckle tracking automatic border detection improves echocardiographic evaluation of right ventricular systolic function in repaired tetralogy of fallot patients: comparison with MRI findingsP553Echocardiography: a reproducible and relevant tool in pah? intermediate results of the multicentric efort echogardiographic substudy (evaluation of prognostic factors and therapeutic targets in pah)Assessment of diastolic functionP554Relationship between left ventricular filling pressures and myocardial fibrosis in patients with uncomplicated arterial hypertensionP555Cardiac rehabilitation improves echocardiographic parameters of diastolic function in patients with ischemic heart diseaseP556Diastolic parameters in the calcified mitral annulusP557Biomarkers and echocardiography - combined weapon to diagnose and prognose heart failure with and without preserved ejection fractionP558Diastolic function changes of the maternal heart in twin and singleton pregnancyIschemic heart diseaseP559Syntax score as predictor for the correlation between epicardial adipose tissue and the severity of coronary lesions in patients with significant coronary diseaseP560Impact of strain analysis in ergonovine stress echocardiography for diagnosis vasospastic anginaP561Cardiac magnetic resonance tissue tracking: a novel method to predict infarct transmurality in acute myocardial infarctionP562Infarct size is correlated to global longitudinal strain but not left ventricular ejection fraction in the early stage of acute myocardial infarctionP563Magnetic resonance myocardial deformation assessment with tissue tracking and risk stratification in acute myocardial infarction patientsP564Increase in regional end-diastolic wall thickness by transthoracic echocardiography as a biomarker of successful reperfusion in anterior ST elevation acute myocardial infarctionP565Mitral regurgitation is associated with worse long-term prognosis in ST-segment elevation myocardial infarction treated with primary percutaneous coronary interventionP566Statistical significance of 3D motion and deformation indexes for the analysis of LAD infarctionHeart valve DiseasesP567Paradoxical low gradient aortic stenosis: echocardiographic progression from moderate to severe diseaseP568The beneficial effects of TAVI in mitral insufficiencyP569Impact of thoracic aortic calcification on the left ventricular hypertrophy and its regression after aortic valve replacement in patients with severe aortic stenosisP570Additional value of exercise-stress echocardiography in asymptomatic patients with aortic valve stenosisP571Valvulo-arterial impedance in severe aortic stenosis: a dual imaging modalities studyP572Left ventricular mechanics: novel tools to evaluate left ventricular performance in patients with aortic stenosisP573Comparison of long-term outcome after percutaneous mitral valvuloplasty versus mitral valve replacement in moderate to severe mitral stenosis with left ventricular dysfunctionP574Incidence of de novo left ventricular dysfunction in patient treated with aortic valve replacement for severe aortic regurgitationP575Transforming growth factor-beta dependant progression of the mitral valve prolapseP576Quantification of mitral regurgitation with multiple jets: in vitro validation of three-dimensional PISA techniqueP577Impaired pre-systolic contraction and saddle-shape deepening of mitral annulus contributes to atrial functional regurgitation: a three-dimensional echocardiographic studyP578Incidence and determinants of left ventricular (lv) reverse remodeling after MitraClip implantation in patients with moderate-to severe or severe mitral regurgitation and reduced lv ejection fractionP579Severe functional tricuspid regurgitation in rheumatic heart valve disease. New insights from 3D transthoracic echocardiographyP58015 years of evolution of the etiologic profile for prosthetic heart valve replacement through an echocardiography laboratoryP581The role of echocardiography in the differential diagnosis of prolonged fever of unknown originP582Predictive value for paravalvular regurgitation of 3-dimensional anatomic aortic annulus shape assessed by multidetector computed tomography post-transcatheter aortic valve replacementP583The significance and advantages of echo and CT imaging & measurement at transcatherter aortic valve implantation through the left common carotid accessP584Comparison of the self-expandable Medtronic CoreValve versus the balloon-expandable Edwards SAPIEN bioprostheses in high-risk patients undergoing transfemoral aortic valve implantationP585The impact of transcatheter aortic valve implantation on mitral regurgitation severityP586Echocardiographic follow up of children with valvular lesions secondary to rheumatic heart disease: Data from a prospective registryP587Valvular heart disease and different circadian blood pressure profilesCardiomyopathiesP588Comparison of transthoracic echocardiography versus cardiac magnetic for implantable cardioverter defibrillator therapy in primary prevention strategy dilated cardiomyopathy patientsP589Incidence and prognostic significance of left ventricle reverse remodeling in a cohort of patients with idiopathic dilated cardiomyopathyP590Early evaluation of diastolic function in fabry diseaseP591Echocardiographic predictors of atrial fibrillation development in hypertrophic cardiomyopathyP592Altered Torsion mechanics in patients with hypertrophic cardiomyopathy: LVOT-obstruction is the topdog?P593Prevention of sudden cardiac death in hypertrophic cardiomyopathy: what has changed in the guidelines?P594Coronary microcirculatory function as determinator of longitudinal systolic left ventricular function in hypertrophic cardiomyopathyP595Detection of subclinical myocardial dysfunction by tissue Doppler ehocardiography in patients with muscular dystrophiesP596Speckle tracking myocardial deformation analysis and three dimensional echocardiography for early detection of chemotherapy induced cardiac dysfunction in bone marrow transplantation patientsP597Left ventricular non compaction or hypertrabeculation: distinguishing between physiology and pathology in top-level athletesP598Role of multi modality imaging in familiar screening of Danon diseaseP599Early impairment of global longitudinal left ventricular systolic function independently predicts incident atrial fibrillation in type 2 diabetes mellitusP600Fetal cardiovascular programming in maternal diabetes mellitus and obesity: insights from deformation imagingP601Longitudinal strain stress echo evaluation of aged marginal donor hearts: feasibility in the Adonhers project.P602Echocardiographic evaluation of left ventricular size and function following heart transplantation - Gender mattersSystemic diseases and other conditionsP603The impact of septal kinetics on adverse ventricular-ventricular interactions in pulmonary stenosis and pulmonary arterial hypertensionP604Improvement in right ventricular mechanics after inhalation of iloprost in pulmonary hypertensionP605Does the treatment of patients with metabolic syndrome correct the right ventricular diastolic dysfunction?P606Predictors of altered cardiac function in breast cancer survivors who were treated with anthracycline-based therapyP607Prevalence and factors related to left ventricular systolic dysfunction in asymptomatic patients with rheumatoid arthritis: a prospective tissue-doppler echocardiography studyP608Diastolic and systolic left ventricle dysfunction presenting different prognostic implications in cardiac amyloidosisP609Diagnostic accuracy of Bedside Lung Ultrasonography in Emergency (BLUE) protocol for the diagnosis of pulmonary embolismP610Right ventricular systolic dysfunction and its incidence in breast cancer patients submitted to anthracycline therapyP611Right ventricular dysfunction is an independent predictor of survival among cirrhotic patients undergoing liver transplantCongenital heart diseaseP612Hypoplasia or absence of posterior leaflet: a rare congenital anomaly of the mitral valveP613ECHO screening for Barlow disease in proband's relativesDiseases of the aortaP614Aortic size distribution and prognosis in an unselected population of patients referred for standard transthoracic echocardiographyP615Abdominal aorta aneurysm ultrasonographic screening in a large cohort of asympromatic volounteers in an Italian urban settingP616Thoracic aortic aneurysm and left ventricular systolic functionStress echocardiographyP617Wall motion score index, systolic mitral annulus velocity and left ventricular mass predicted global longitudinal systolic strain in 238 patients examined by stress echocardiographyP618Prognostic parameters of exercise-induced severe mitral valve regurgitation and exercise-induced systolic pulmonary hypertensionP619Risk stratification after myocardial infarction: prognostic value of dobutamine stress echocardiographyP620relationship between LV and RV myocardial contractile reserve and metabolic parameters during incremental exercise and recovery in healthy children using 2-D strain analysisP621Increased peripheral extraction as a mechanism compensatory to reduced cardiac output in high risk heart failure patients with group 2 pulmonary hypertension and exercise oscillatory ventilationP622Can exercise induced changes in cardiac synchrony predict response to CRT?Transesophageal echocardiographyP623Fully-automated software for mitral valve assessment in chronic mitral regurgitation by three-dimensional transesophageal echocardiographyP624Real-time 3D transesophageal echocardiography provides more accurate orifice measurement in percutaneous transcatheter left atrial appendage closureP625Percutaneous closure of left atrial appendage: experience of 36 casesReal-time three-dimensional TEEP626Real-time three-dimensional transesophageal echocardiography during pulmonary vein cryoballoon ablation for atrial fibrilationP627Three dimensional ultrasound anatomy of intact mitral valve and in the case of type 2 disfunctionTissue Doppler and speckle trackingP629Left ventricle wall motion tracking from echocardiographic images by a non-rigid image registrationP630The first experience with the new prototype of a robotic system for remote echocardiographyP631Non-invasive PCWP influence on a loop diuretics regimen monitoring model in ADHF patients.P632Normal range of left ventricular strain, dimensions and ejection fraction using three-dimensional speckle-tracking echocardiography in neonatesP633Circumferential ascending aortic strain: new parameter in the assessment of arterial stiffness in systemic hypertensionP634Aortic vascular properties in pediatric osteogenesis imperfecta: a two-dimensional echocardiography derived aortic strain studyP635Assessment of cardiac functions in children with sickle cell anemia: doppler tissue imaging studyP636Assessment of left ventricular function in type 1 diabetes mellitus patients by two-dimensional speckle tracking echocardiography: relation to duration and control of diabetesP637A study of left ventricular torsion in l-loop ventricles using speckle-tracking echocardiographyP638Despite No-Reflow, global and regional longitudinal strains assessed by two-dimensional speckle tracking echocardiography are predictive indexes of left ventricular remodeling in patients with STEMIP639The function of reservoir of the left atrium in patients with medicaly treated arterial hypertensionP640The usefulness of speckle tracking analysis for predicting the recovery of regional systolic function after myocardial infarctionP641Two dimensional speckle tracking echocardiography in assessment of left ventricular systolic function in patients with rheumatic severe mitral regurgitation and normal ejection fractionP642The prediction of left-main and tripple vessel coronary artery disease by tissue doppler based longitudinal strain and strain rate imagingP643Role of speckle tracking in predicting arrhythmic risk and occurrence of appropriate implantable defibrillator Intervention in patients with ischemic and non-ischemic cardiomyopathyComputed Tomography & Nuclear CardiologyP644Cardiac adrenergic activity in patients with nonischemic dilated cardiomyopathy. Correlation with echocardiographyP645Different vascular territories and myocardial ischemia, there is a gradient of association?

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Scali, F Valente, G Joseph, SJ Ha, J D Morales Portano, S Prado Diaz, P Trzcinski, JN Codolosa, C Contaldi, M Orabona, M Chinali, A Lisowska, S Stoebe, A Shetye, SELEN Yurdakul, J Ternacle, JM Ribeiro, T T Le, VY Mo, O Vriz, BW Michalski, N Hanboly, G Mehdipoor, T Erdei, A Garcia Campos, L Badano, S Martins Fernandes, R Teixeira, I Roussin, M Lynch, D Muraru, G Romeo, D Ermacora, C Marotta, P Aruta, U Cucchini, S Iliceto, M Martin-Fernandez, JM De La Hera Galarza, C Corros-Vicente, S Colunga Blanco, E Velasco-Alonso, V Leon-Aguero, ML Rodriguez-Suarez, C Moris De La Tassa, J Edwards, D Braim, C Price, AG Fraser, F Salmani, A Arjmand Shabestari, E Szymczyk, K Kupczynska, L Peczek, B Nawrot, P Lipiec, JD Kasprzak, C Driussi, F Ferrara, G Brosolo, F Antonini-Canterin, J Magne, V Aboyans, E Bossone, BM Bellucci, JM Fisher, AA Balekian, S Idapalapati, F Huang, JI Wong, RS Tan, M Madeira, I Almeida, A Siserman, P Dinis, L Dias, AP Ramos, L Goncalves, FW Wan, DS Sawaki, JLDR Dubois-Rande, SA Adnot, GC Czibik, GD Derumeaux, G Ercan, ILKER Tekkesin, ST Sahin, B Cengiz, G Celik, S Demircan, SAIDE Aytekin, NA Razvi, SA Nazir, N Price, JN Khan, P Kanagala, A Singh, I Squire, GP Mccann, M Langel, D Pfeiffer, A Hagendorff, K Ptaszynska-Kopczynska, M Marcinkiewicz-Siemion, M Knapp, M Witkowski, WJ Musial, K Kaminski, B Natali, C D' Anna, B Leonardi, A Secinaro, G Pongiglione, G Rinelli, S Renard, N Michel, J Mancini, J Haentjens, O Sitbon, G Habib, M Imbriaco, G Alcidi, C Santoro, A Buonauro, F Lo Iudice, M Lembo, A Cuocolo, B Trimarco, M Galderisi, J Mora Robles, MA Roldan Jimenez, MA Mancisidor, MA De Mora, T Alnabelsi, I Goykhman, N Koshkelashvili, A Romero-Corral, GS Pressman, D Miskowiec, N Montoro Lopez, E Refoyo Salicio, SC Valbuena Lopez, O Gonzalez, C Alvarez, M Moreno Yanguela, JL Bartha Rasero, M De La Calle, G Guzman Martinez, JA Suarez-Cuenca, JA Merino, E B Gomez Alvarez, LG Delgado, YM Woo, WD Bang, GH Sohn, SS Cheong, SY Yoo, JF Rodriguez Palomares, L Gutierrez, G Maldonado, V Pineda, L Galian, G Teixido, MT Gonzalez Allujas, A Evangelista, D Garcia Dorado, T Zaremba, S Ekeloef, E Heiberg, H Engblom, SE Jensen, P Sogaard, G Garcia, FL Dini, F Galli, F Lattanzi, E Picano, M Marzilli, S Leao, M Moz, P Magalhaes, J Trigo, PS Mateus, A Ferreira, JI Moreira, M De Craene, D Legallois, F Labombarda, A Pellissier, M Sermesant, E Saloux, M Merlo, M Moretti, G Barbati, D Stolfo, M Gigli, B Pinamonti, G Sinagra, E Dores, A Matera, P Innelli, A Lopizzo, R Violini, R Fiorilli, G Cappabianca, G Tarsia, J Seo, HJ Chang, R Heo, IC Kim, CY Shim, GR Hong, N Chung, MM Melissopoulou, V Nguyen, E Brochet, C Cimadevilla, I Codogno, A Vahanian, D Messika-Zeitoun, F Pontana, V Vassiliou, S Prasad, C Leclercq, E Samset, E Donal, DS Lim, G Bianchi, F Rossi, J Gianetti, F Marchi, E Cerone, A Nardelli, M Terrazzi, M Solinas, S Maffei, A Pshepiy, L Vasina, E Timofeev, S Reeva, E Zemtsovsky, N Brugger, S Jahren, SF De Marchi, C Seiler, CN Jin, H Tang, K Fan, K Kam, BP Yan, CM Yu, PW Lee, M Reali, E Silvetti, T Salatino, M Mancone, M Pennacchi, A Giordano, G Sardella, L Agati, G Tirado, MT Nogales-Romo, P Marcos-Alberca, A De Agustin, C Almeria, JL Rodrigo, MA Garcia Fernandez, C Macaya, L Perez De Isla, M Mancisidor, C Lara Garcia, R Vivancos, M De Mora, M Petrovic, B Vujisic-Tesic, M Boricic-Kostic, I Petrovic, G Draganic, O Petrovic, M Tomic-Dragovic, T Furlan, J Ambrozic, PN Mohorko Pleskovic, M Bunc, R Ribeiras, J Abecasis, MJ Andrade, M Mendes, S Ramakrishnan, SK Gupta, R Juneja, SS Kothari, M Zaleska, A Segiet, S Chwesiuk, A Kroc, DA Kosior, D Andreini, A Solbiati, M Guglielmo, S Mushtaq, A Baggiano, V Beltrama, C Rota, AI Guaricci, M Pepi, J Pons Llinares, P Pericas Ramis, O Caldes Llull, A Grau Sepulveda, G Frontera, A Vaquer Segui, M Noris, A Bethencourt Gonzalez, V Climent Paya, M Martinez Moreno, D Saura, MJ Oliva, J Sanchez Quinones, A Garcia Honrubia, M Valdes, G De La Morena, M Terricabras, JP Costabel, R Ronderos, C Venturini, E Galve, A Nemes, S Neubauer, S Rahman Haley, N Banner, F Caetano, A Botelho, J Silva, J Nascimento, M Tesic, I Jovanovic, M Dragovic, J Stepanovic, M Banovic, V Guergelcheva, T Chamova, S Sarafov, I Tournev, S Denchev, I Ikonomidis, P Psarogiannakopoulos, P Tsirigotis, I Paraskevaidis, J Lekakis, A Pelliccia, BM Natali, M Focardi, M Bonifazi, S Mondillo, C Lima, L Assed, R Kalil Filho, C Mady, E A Bochi, V M C Salemi, G Targher, F Valbusa, A Rossi, P Lipari, L Zenari, G Molon, G Canali, E Barbieri, M Craft, M Nanda, JM Lorenzo, S Kutty, T Bombardini, S Sparla, C Di Tommaso, M Losito, E Incampo, M Maccherini, A Werther Evaldsson, G Radegran, M Stagmo, J Waktare, A Roijer, CJ Meurling, W Hui, FJ Meijboom, B Bijnens, A Dragulescu, L Mertens, MK Friedberg, B Sensoy, M Suleymanoglu, Y Akin, E Sahan, H Sasmaz, L Pasca, E Buzdugan, B Chis, L Stoicescu, FC Lynce, KL Smith, M Mete, C Isaacs, O Viapiana, C Di Nora, F Ognibeni, E Fracassi, A Giollo, C Mazzone, G Faganello, A Di Lenarda, M Rossini, A Galrinho, L Branco, A T Timoteo, I Rodrigues, P Daniel, S Rosa, L Ferreira, R Ferreira, L Polak, G Krauza, K Stokfisz, M Zielinska, L M Branco, M Mota Carmo, A Teresa Timoteo, S Aguiar Rosa, J Abreu, P Pinto Teixeira, A Viveiros Monteiro, R Cruz Ferreira, T Peeraphatdit, R Chaiteerakij, KW Klarich, S Masia, J Necas, S Nistri, F Negri, G Russo, C Pandullo, A Durante, E Rovelli, V Genchi, L Trabattoni, SC Zerboni, L Cattaneo, E Butti, G Ferrari, E Luneva, L Mitrofanova, V Uspensky, S Rosner, M Karl, I Ott, C Sonne, HM Ali Lahmar, L Hammou, J Forsey, L Gowing, F Miller, P Ramanujam, AG Stuart, CA Williams, F Bandera, M Pellegrino, F Carbone, V Labate, E Alfonzetti, M Guazzi, NR Patel, P Raju, L Beale, G Brickley, GW Lloyd, C Fernandez-Golfin, A Gonzalez, LM Rincon, R Hinojar, A Garcia, A Megias, JJ Jimenez-Nacher, JL Moya, JL Zamorano, A Chiampan, L Albrigi, M Noris Mora, A Rodriguez Fernandez, C Exposito Pineda, C Grande, R Gonzalez Colino, X Fernandez Vazquez, E Fortuny Frau, M Karvandi, R Blaszczyk, R Zarczuk, W Brzozowski, M Janowski, A Wysokinski, B Stanczyk, S Myftiu, D Teferici, A Quka, E Dado, J Djamandi, L Kresto, A Duka, A Kristo, I Balla, Z Issa, N Moiduddin, G Siblini, Z Bulbul, L Abid, D Abid, S Kammoun, E Rush, J Goodwin, R Kreikemeier, M Cantinotti, M A Zolaly, SQ Khoshhal, K El-Harbi, A Tarawah, Z Al-Hawsawi, I Al-Mozainy, S W G Bakhoum, M N Nabil, I N Elebrashy, S Albanese, A Carotti, R Iacobelli, C Esposito, G Moscogiuri, L Pasquini, M Malvezzi Caracciolo, RM Bianchi, P Caso, F Arenga, L Riegler, R Scarafile, A D'andrea, MG Russo, P Calabro', DS Simic, VP Peric, NM Mujovic, MM Marinkovic, NJ Jankovic, A Shim, P Wejner-Mik, N Jain, R Kharwar, RK Saran, VS Narain, SK Dwivedi, R Sethi, S Chandra, A Pradhan, S Safal, MF Marchetti, C Cacace, M Congia, V Nissardi, M Ruscazio, L Meloni, R Montisci, G Gallego Sanchez, S Calero, JJ Portero, A Tercero, JC Garcia, M Barambio, R Martinez Lazaro, AH Meretta, GO Perea, F Belcastro, E Aguirre, I De Luca, R Henquin, and O Masoli
Subjects: medicine.medical_specialty, Ejection fraction, Longitudinal strain, business.industry, General Medicine, Deformation (meteorology), medicine.disease, Infarct size, Surgery, Internal medicine, Cardiology, Medicine, Radiology, Nuclear Medicine and imaging, Myocardial infarction, Stage (cooking), Cardiology and Cardiovascular Medicine, business, Radial stress, Relevant information
Abstract: Purpose: Deformation analysis from 3D echocardiography results in a considerable amount of parameters, for which the conventional statistical approach is cumbersome. We investigate local motion and deformation patterns to determine the parameters of relevance for the study of LV myocardial deformation in the presence of LAD infarct. Methods: The study included 46 patients acquired at max. 5 days after LAD infarct (37 sequences) and at 1-year follow-up (33 sequences), and 46 controls. Patients were selected if they had a LVEF
Published: 2015
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9. P1643Calcification and inflammation in aortic stenosis - are the mechanisms in tricuspid and bicuspid aortic valve different?

Author: P Murtazalieva, E Malev, Olga Irtyuga, Olga Moiseeva, and E Zhiduleva
Subjects: Stenosis, medicine.medical_specialty, Bicuspid aortic valve, business.industry, Internal medicine, Cardiology, Medicine, Inflammation, medicine.symptom, Cardiology and Cardiovascular Medicine, business, medicine.disease
Published: 2017
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10. Poster session Friday 13 December - PM: 13/12/2013, 14:00-18:00 * Location: Poster area

Author: A. Rojek, M. Bekbossynova, J. Onaindia, R. Ferrer Lopez, B. Javani, A. Sharif-Rasslan, N. Al, R. Davies, U. Ikeda, R. Ferreira, A. Cincin, M. Plewka, F. Weidemann, B. Fadel, O. Akgul, Z. Frikha, M. Haghjoo, J. Jensen, G. Agoston, M. Sunbul, R. Strasser, M. Pepi, Y. Fuku, M. Minamisawa, J. Holm, O. Dzikowska Diduch, Y. Pya, J. Macancela Quinones, P. Gaudron, G. Ertl, S. Thivolet, C. Koukoulis, H. Yun, S. Iancovici, D. Capodanno, M. Barthelet, A. Medeiros-Domingo, T. Le Tourneau, A. P. Lee, G. Derumeaux, I. Rodriguez, B. Naegeli, S. Rahmatullah, A. Bayes, H. Schaff, A. M. Caggegi, C. Zito, M. D'alto, R. Favilli, J. Baan, M. Aydin, J. Bonaque Gonzalez, A. Akhundova, I. Cruz, R. Karpov, H. Okura, D. Dequanter, M. T. Grillo, A. Ingvarsson, S. Prasad, A. Dahiya, U. Rosenschein, G. Sinagra, J. Kochanowski, M. Niemann, Y. Saijo, B. Bouma, K. Sveric, Y. Topilsky, M. Ministeri, J. Piek, C. Marinescu, M. Bilik, I. Ikuta, M. Al-Admawi, C. Araujo, D. Trifunovic, S. Onciul, G. Pavlidis, F. Ruiz Lopez, M. Oyumlu, C. Kenny, F. Kayan, C. Ginghina, R. Piatkowski, I. Lekuona Goya, A. Almeida, G. Portugal, H. Motoki, M. Cinteza, B. Seifert, S. Lee, M. Banovic, T. Sakakura, A. Pappalardo, B. Stuart, Y. Chuyasova, T. Yamanaka, N. Roche, C. Wunderlich, X. Arana, L. Ernande, V. Ribeiro, Y. Tanabe, L. Vazdar, Y. Tayyareci, E. Malev, M. Eren, J. Gil, S. Lunghetti, D. Krieger, S. Mangiafico, M. Izumo, D. Cacela, A. Kovacs, A E Van Den Bosch, E. Reffo, P. G. Jorgensen, O. Dubourg, J. Abreu, S. Wang, E. Cervesato, K. Theodoropoulos, N. Ozaydogdu, L. Jung, Y. Kijima, E. Ostenfeld, C. Corsi, M. Florescu, M. Chenilleau, K. Yokota, A. Faeh-Gunz, R. Winter, J. Dreyfus, D. Kang, S. K. Saha, S. Surdulli, L. Abikeyeva, M. Marchel, P. Meregalli, M. Yamat, X. Arana Achaga, C. Shahla, V. Palicka, M. Tanaka, A. Galrinho, K. Endo, M. Saravi, J. Bogaert, H. Oeygarden, S. Okabe, J. Reiken, G. Ionescu, C. Selton-Suty, A. Nunes-Diogo, E. S. Davidsen, E. Kinova, A. Bandeira, Y. Seo, S. Hojberg, G. Siblini, M. Pellegrino, M. Ostojic, J. J. Onaindia Gandarias, M. Pereira, F. Antonini-Canterin, F. Akturk, T. Nakajima, M. Al Fayyadh, S. Herrmann, G. Stellin, M. E. Menting, B. Sasko, J. Song, T. Kurokawa, F. Dipasqua, T. Maruo, M. Geleijnse, H. Triantafyllidi, M. Komeda, R. Praus, V. Nesvetov, M. Fineschi, A. Auricchio, M. Dorobantu, A. Degirmencioglu, E. Laraudogoitia Zaldumbide, S. Velasco Del Castillo, Z. Marcetic, U. Waje-Andreassen, F. Fang, K. Farsalinos, L. Vasina, D. Muraru, M. Faludi, P. Rio, S. Peppes, T. Karaahmet, G. Suermeci, P. Maccarthy, S. Kotsovilis, Y. Akashi, G. Di Salvo, Z. Issa, J. Gibbs, A. Poletti, E. Bonnefoy-Cudraz, A. Madej-Pilarczyk, E. Gerdts, K. Solymossy, P. Kogoj, T. Tomita, M. Lisi, K. Suzuki, S. Sifakis, E.A. Surkova, T. Fritz-Hansen, V. Tritakis, E. Romeo, T. Akesson-Lindow, B. Lasota, A. Florian, M. Maciel, K. Gieszczyk-Strozik, M. Imazio, S. Ozyilmaz, K. Kadota, V. Peric, E. Zencirci, B. Tzvetkov, U. Aguirre Larracoechea, D. Caldeira, Y. Motoyoshi, M. Russo, R. Suri, H. Pintaric, O. Celik, D. Himbert, L. Branco, B. Sun, S. Dzhetybayeva, A. Esen Zencirci, M. Ciurzynski, R. Nunyez, B. Iung, K. Takenaka, A. S. Omran, K. Ozden, J. Argacha, S. Pradel, A. M. Pistritto, M. Pfyffer, C. Dedobbeleer, J. Vojacek, P. Costa, E. Albuquerque, A. Tamadoni, B. Sarubbi, M. Carlsson, R. Mogelvang, G. Oria, K. Kimura, E. Kim, F. Kousathana, A. Mateescu, A. Varga, J. Clerc, M. Noni, S. Kyrzopoulos, S. Andossova, S. Almeida, E. Shkolnik, J. Koyama, M. Daimon, S. Saeed, B. Popescu, M. Tigen, R. Wennemann, C. Venner, M. Guazzi, R. Magalhaes, H. Hayashi, M. Salagianni, A. Kiotsekoglou, A. Baggiano, C. Chao, T. Nakao, H. Becher, R. Zeppellini, J. Marrugat, G. Erente, P. Lancellotti, R. Rimbas, D. M'barek, M. Cameli, Y. Katahira, S. Carerj, C. Grasso, P. Moulin, D. Lavergne, B. Merkely, D. Mahoney, C. Tamburino, W. Kosmala, G. Romagna, T. Potpara, T. Ha, R. Biffanti, C. Dundar, E. Gunyeli, L. Weinert, R. Dworakowski, A. Ferreira, T. Biering-Sorensen, H. Engblom, M. Erturk, G. Varlan, M. Ikeda, L. Thorell, S Von Bardeleben, S. Palomar, K. Boerlage-Van Dijk, T. Ishizu, S. Stoerk, I. Germanakis, H. Yamamoto, Q. Shang, A. Borizanova, C. Fiorentini, R. Candinas, U. Inci, F. Macedo, O. Huttin, R. Pudil, I. D. Gabric, C. Silveira, I. Sari, V. Lambadiari, L. Laczmanski, E. Timofeev, A. Izgi, D. Bravo Bustos, K. Wierzbowska-Drabik, P. Masci, H. Pusuroglu, F. Navarro Garcia, P. Adhikari, K. Mizia-Stec, S. Celik, A. Medressova, S. Pala, R. Retkoceri, O. Tautu, S. Tzikas, S. Ohtsuki, T. Akbulut, S. Goliszek, K. Mitsudo, P. Palczewski, A. Spyrou, K. Filipiak, I. Tzoulaki, A. Erdem, M. Krupa, K. Yoshida, M. Polovina, J. Vanoverschelde, H. Pereira, K. Obase, O. V. Tereshina, J. Liebeton, L. Petrescu, W. Gin-Sing, T. A. Warsame, B. Lichodziejewska, M. Takeuchi, J. Cuypers, Y. Jung, E. Martins, S. Mondillo, D. Liu, D. Planinc, I. Subirana, S. Shahrzad, U. Richter, M. Prull, C.H. Attenhofer Jost, E. Alfonzetti, A. Kosztin, V. Carvalho, M. van Bracht, K. Shahgaldi, M. Altman, A. Cacicedo, R. Dulgheru, M. Arslan, L. Dell'angela, M. De Biasio, J. Roos-Hesselink, A. Sawant, B. Ghadrdoust, H. Tabuchi, I. Rangel, M. Aguado Martin, L. Pedro-Botet, K. Koch, G. Zugazabeitia Irazabal, I. Hausmanowa-Petrusewicz, A. Werther-Evaldsson, A. Korshunova, Q. Zhang, A. Anton Ladislao, C. Bergerot, F. Karlsen, T. Akagi, M. Jasinski, I. Komuro, A. Apor, L. Fourcade, P. Argiento, E. Zemtsovsky, A. Correra, J. Chudek, S. Choi, G. Barletta, A. Varela, A. Manouras, H. Oe, A. D'andrea, S. Ramezani, M. Akil, A. Azevedo, S. Imme, A. Ionac, E. Saracoglu, K. Nakagawa, O. Vinter, S. Reeva, G. Van Camp, T. Forster, T. Butz, I. Ikonomidis, A. Costa, M. Ruiz Lopez, D. Vinereanu, G. Opolski, K. Akay, A. Vrublevsky, J. Silva Marques, L. Sousa, F. D'ascenzi, N. Oprescu, F. Veronesi, A. Mysiak, R. Dan, M. Nobre Menezes, D. Kim, V. Vida, Y. Kim, V. Di Bello, D. Sharif, A. I. Nagy, A. Sikora-Puz, H. Moladoust, C. Florescu, M. Kostrubiec, L. Pierard, E. Ural, A. Goncalves, K. Grudzka, A. Charalampopoulos, A. Luycx-Bore, M. Wilkins, S. Mushtaq, D. Messika-Zeitoun, N. Olsen, C. Mornos, M. Tesic, R. Symons, S. Bekbossynov, H. Erer, M. Kokorina, I. Joao, C. Cotrim, D. Voilliot, M. Yamawaki, N. Roszczyk, J. Inamo, C. Sousa, A. Porto, I. Lekakis, A. G. Caelian, D. Rigopoulos, T. Komori, G. Pontone, S. Scandura, F. Melao, N. Toh, A. Neikova, V. Aboyans, S. La Carrubba, D. Zamfir, S. Dymarkowski, J. Magne, G. Szeplaki, S. Velasco, J. Mcghie, M. Losito, L. Shkolnik, M. Petrovic, I. Papadakis, D. Brito, I. Schilling, O. Bech-Hanssen, M. Enriquez-Sarano, C. Lafaras, O. Enescu, B. Bijnens, R. Lang, C. Lestuzzi, C. Kirma, N. Vallejo, F. Elmkies, M. Vasatova, N. Uslu, M. Yuksel, M. Anastasiou-Nana, G. Gatti, O. Milanesi, V. Donghi, A. Kozuka, C. Henri, K. Tsimopoulou, G. Karakus, A. Cerutti, J. Macancela Quinonez, E. Laraudogoitia, P. Unger, A. Roijer, K. Kurnicka, M. Carasi, D. Djikic, M. Dragovic, H. Aksu, S. Srivatsa, A. Khan, N. Maschietto, D. Cozma, V. Andreakos, C. Meurling, O. Wendler, C. Doulaptsis, E. Aliot, T. Damy, Z. Ojaghihaghighi, L. Mateu, S. Knop, M. Vis, M. Mizia, A. Khalil, E. Abate, M. Gomez Recio, J. Ko, M. Seo, D. Tsiapras, E. Tekbas, C. Celeng, K. Aonuma, M. Przewlocka-Kosmala, S. Laaraibi, T. Sahin, D. Mohty, P. Jorgensen, A. Fiarresga, C. Scharf, E. Conte, V. Pergola, C. Jons, M. Padalino, R. Krecki, M. Malicse, F. Parthenakis, N. Bolivar Herrera, G. Foldes, O. Vriz, J. Kasprzak, S. Janssens, H. Bejiqi, H. Nakajima, R. Naeije, E. Papadavid, A. Subinas, R. Calabro, M. Trbusic, W. Tomkowski, M. Ooshima, A N Vachev, A. Fotaki, E. Brochet, F. Scholz, A. Boshchenko, P. Massoure, S. Munoz Troyano, J. Zumalde, M. Tsakalou, E. Bertella, M. Carminati, A. Kalkan, Y. Miyashita, I. Comanescu, A. M. Esen, K. Nakamura, A. Sanchez Espino, G. Berkenboom, H. Trappe, B. Castaldi, M. Cielecka-Prynda, Y. Otsuji, R. Bejiqi, E. Caiani, A. Moreo, P. Vaida, J. Castillo, S. Stankovic, C. Davos, H. Murata, T. Komiya, K. Berta, A. Aussoleil, A. Yildiz, B. Piamonti, K. Sato, J. Silva-Cardoso, I. Popescu, R. Pap, A. Serafin, K. Addetia, F. Olsen, J. Cautela, C. Yu, R. El Mahmoud, C. Cardoso, N. Echahidi, V. Pyankov, T. Yamada, R. Hoffmann, H. Johno, L. Lopes, R. Li, R. Onut, J. Lekakis, G. Nicolosi, N. Watanabe, Y. Basaran, A. Matos, A. Chmiel, N. Host, M. Sabria, N. Gronkova, P. Hulek, H. Cakmak, E. Wiegerinck, A. Goudev, A. Romero Pereiro, A. Pellegrini, L. Badano, P. Cameli, N. Abdullah, M. Deja, A. Ekmekci, A. Vahanian, A. Retkoceri, V. Mor-Avi, H. Ito, N. Bindraban, T. Rigo, R. Vanderpool, N. Mansencal, M. K. Tigen, J. Bech, H. Thibault, A. Pshepiy, A. Decker-Bellaton, L. Saghy, Z. Al Bulbul, G. Generati, I. Nedeljkovic, Y. Kuatbayev, G. A. Derumeaux, M. Varoudi, Y. Juilliere, K. Uno, P. Virot, B.M. van Dalen, M. Witsenburg, E. Yamashita, K. Okada, E. Gomez, P. Pinto-Teixeira, T. Yambe, N. Preumont, K. Hu, R. Jalalian, A. Formenti, M. Monaghan, P. Pruszczyk, L. Massa, D. Andreini, A. Fromm, E. Stoupel, D. Ural, R. Pilliere, L. Llobera, W. Kim, M. Sobczak, F. Bandera, S. Oliveira, P. Mills, H. Zemir, E. Oner, S. Sparla, C. Cosgrove, S. Kou, A. Annoni, B. Vujisic-Tesic, M. Hojati, L. Carr, P. Meimoun, A. Jaccard, E. Varotto, N. Bulj, T. Kawata, M. Bulut, G. Dimitriadis, B. Ramondo, V. Voudris, H. Christensen, H. Eguchi, J. Grapsa, P. R. Silva Fazendas Adame, C. Cimadevilla, L. Christensen, M. Cikes, A. Izawa, G. Merchan Ortega, A. Makrigiannakis, M. Forkmann, G. Radegran, P. Dias, A. Faiz, C. Stefopoulos, Y. Vasyuk, A. Akyol, L. Howard, A. Correia, J. Younger, and C. Greis
Subjects: medicine.medical_specialty, business.industry, medicine, Radiology, Nuclear Medicine and imaging, Medical physics, General Medicine, Session (computer science), Cardiology and Cardiovascular Medicine, business
Published: 2013
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11. Poster session: Aortic stenosis

Author: R. Piccolo, J. Clarke, C. A. Brambila, B. Igual Munoz, K. Hristova, M. S. Carvalho, M. Tesic, O. Azevedo, J. A. Del Prado, A. Mcculloch, O. Kaitozis, B. Popovic, S. Stankovic, H. Chamsi-Pasha, R. Abdelfatah, V. Parisi, K. Pushparajah, E. Zemtsovsky, B. Kilickiran Avci, A. Manouras, K. Takenaka, F. Parthenakis, P. Vardas, A. Goudev, M. Orii, A. Kutarski, R. De Rosa, M. Castillo Orive, A. Sahlen, H. Ahn, S. Nedjati-Gilani, G. J. King, H. Bellsham-Revell, D. Lahidheb, M. Anastasiou-Nana, F. Pereira Machado, S. Yurdakul, N. Olsen, S. Pica, A. Ebihara, T. Nakajima, P. Molina Aguilar, R. Hornsten, M. Elnoamany, M. Cramer, G. Tamborini, G. Pagano, H. Kim, S. Soderberg, A. M. Gonzalez, N. Zlatareva, E. Marangio, F. Yang, G. Cho, I. Paunovic, C. Jons, T. Tanimoto, H. Triantafyllidi, D. Gopalan, O. Ozcan, M. Norman, G. Grazioli, F. Castillo, E. Kort, R. Bruno, J. Kostic, M. Daimon, D. Kang, C. Badiu, C. Magnino, C. Bucca, I. Joao, F. Buendia Sanchez, A. Tomaszewski, M. Alasnig, J. Kisslo, T. Kawata, S. Fernandez Casares, A. Livingston, J. Silva Cardoso, S. Korkmaz, J. Rodriguez Garcia, M. Tomaszewski, Y. Motoyoshi, A. Kaneva, E. Kinova, J. Lekakis, N. Bruun, M. Elneklawy, K. Uno, K. Nour, J. M. Ferrer, T. Wada, T. Katova, E. Ermis, F. Gaita, S. Rafla, F. Macedo, S. Woo, S. Perry, M. Lonnebakken, K. Thapa, M. Banovic, C. Selton-Suty, V. Pereira, A. Lourenco, G. Dreyfus, W. Serra, M. Hedstrom, A. Hagendorff, H. Nishino, T. Filali, M. Muratori, F. De Stefano, J. Marin, B. Jedaida, I. Rangel, J. Haertel, S. Tzortzis, A. Kalogerakis, G. Galasso, P. Hoffman, L. Chen, Y. Juilliere, V. Kostova, J. Navarro Manchon, C. J. Lopez-Guarch, J L Moya Mur, J. D. J. Baguda, C. Moretti, C. Manisty, N. Hajlaoui, H. Mahfoudhi, E. Martins, F. Bourlon, Y. Choi, C. Papadopoulos, A. Santos, I. V. Vassiliadis, A. Pereira, D. Domingo Valero, P. Iacotucci, C. Fernandez-Golfin, P. Li, I. Xanthopoulou, G. Pontone, R. Tan, D. D. Valero, D. Cramariuc, D. Lovric, F. Maffessanti, V. Pehar Pejcinovic, Y. Xu, M. Gurzun, L. Mitrofanova, P. Sousa, M. Miglioranza, A. Goncalves, I. Nedeljkovic, S. Stanic, C Di Mario, Y. Shiono, Y. Bian, E. Tossavainen, N. Risum, L. Sargento, K. Hirata, K. Said, H. Park, A. M. Argudo, T. Kubo, S. Barker, A. Chetta, R. Palma Reis, E. Malev, C. Yao, I. Papadakis, R. Medeiros, J. Tong, M. Previtali, T. Yamaguchi, S.-H. Shin, M. Sitges, C. Calinescu, J. Rueda Soriano, K. Steine, R. Ichikawa, K. Farouk, S. Pedri, J. Ripsweden, S. Carillo, G. Gelbrich, P. Rees, F. Costantino, S. Hutchings, A. Bel Minguez, A. Gaspar, M. Petrovic, M. Li Kam Wa, E. Mavronasiou, R. Winter, I. Quelhas, J. Johnson, A. Gopal, H. Jurin, R. Rordorf, M. Al-Mallah, A. Kydd, M. Ezat, A. M. Duncan, A. Kyriacou, Y. Kim, D. Mihalcea, J. Lessa, L. Mont, T. Fritz Hansen, J. Separovic Hanzevacki, D. Mesa, R. Mincu, G. Pavlidis, A.D.J. Ten Harkel, L. Gabrielli, F. Civaia, B. Vujisic-Tesic, M. Lourenco, C. Cefalu, C. Alexandrescu, L. Stefani, D. Gerede, M. Bartesaghi, C. Calin, F. Alamanni, A. Giesecke, P. Fazendas, C. Sousa, C. Ginghina, J. Magne, S. Lemoine, M. Gonzalez, C. Gohlke-Baerwolf, K. H. Hirata, S. Fawzi, H. Kisacik, B. Popescu, L. Visconti, W. Brzozowski, M. Driessen, V. Schiano Lomoriello, S. Yamada, I. Machado, F. Silveira, A. Nordin, E. Velazquez, J. Simpson, D. Vasilev, R. Rimbas, R. Murphy, C. Szymanski, T. Imanishi, M. Martirosyan, E. Najjar, J. Chambers, I. Jovanovic, A. Nagorni, E. Gunyeli, M. Omelchenko, P. De Araujo Goncalves, E. Avenatti, R. Marinov, A. Rieck, C. Tribouilloy, I. Sitges, P. Navas Tejedor, N. Lousada, W. Fehri, B. Pezo Nikolic, T. Leiner, C. Lazaro Rivera, H. Pereira, M. Loeffler, R. Hural, D. Caldeira, D. Francis, M. Di Natale, P. Salgado Filho, F. Gao, C. Alm, G. Tarsia, A. Aleixo, D. Vinereanu, C. Cotrim, M. Lotfi, B. Mc Loughlin, H. Morita, S. K. Saha, A. Djordjevic-Dikic, D. Voilliot, R. Camporotondo, J. Shin, P. Pavlov, M. A. Cattabiani, G. Sekita, A. Djordjevic Dikic, K. Ishibashi, C. Pare, J. Kwan, S. Miyazaki, V. Di Tante, E. Svenungsson, V. Giga, Y. Ino, M. Rover, J. Niewiadomska, M. Florescu, I. Skjoerten, C. Wilson, P. Davlouros, M. Hazekamp, N. Moat, A. Correia, C. Tekedis, I. Ikonomidis, B. Dilekci, L. Magda, T. Le, D. Sohn, S. Hamdy, M. Cinteza, R. Enache, A. Milan, R. Dahmani, A. Lopez Granados, J. Zamorano Gomez, E. Zorio Grima, S. Ghulam Ali, B. Demirkan, A. Shehata, M. Vono, M. Chiarlo, Miguel Mota Carmo, D. Trifunovic, B. Bijnens, Y. Yatomi, J J Jimenez Nacher, B. Rogge, R. Nagai, D. Dutka, X. Shen, I. Mordi, M. Henein, F. Celeste, G. Nadais, H. El Atroush, T. Yamano, D. Andreini, B. Beleslin, H. Suzuki, L. Yan, S. Ghio, C. C. De Sousa, S. Stoebe, S. Petrovic-Nagorni, D. Leosco, T. Komori, S. El-Tobgi, S. Mihaila, A. Madureira, T. Leiria, G. Kim, H. Haouala, B. Stuart, G. Touati, K. Oleszczak, M. Ostojic, J. Song, D. Presutti, A. Fournier, H. Daida, M. Perez Guillen, I. Kuipers, H. Hwang, B. Belesiln, K. Park, Y. Guray, D. Pfeiffer, C. Reverberi, A. Lech, A. Valentini, A. Cogo, F. Piscione, S. Negrea, S. Mezghani, V. Pilosoff, P. Sogaard, N. Blom, N. Tzemos, A. Mantovani, K. Okada, A. Turco, M. Peltier, B. Lopez Melgar, U. Guray, Q. Chen, S. Chamuleau, T. Stanton, F. Baeza, S. M. Rafla, J. Roquette, I. Almuntaser, E. Picano, D. Rusinaru, R. Kalil, R. Martin Asenjo, A. Kiotsekoglou, A. Chilingaryan, B. Candemir, P. Sonecki, A. Moulias, M. Rosca, H. Marques, A. Patrianakos, S. Sahin, J. Estornell Erill, O. Enescu, J. Spratt, P. Barbier, M. Maciel, I. Ivanac Vranesic, P. Lindqvist, T. Snow, J. Silva-Cardoso, N. Koutsogiannis, D. Ardissino, L. Zhong, K. Adamyan, L. Mccormick, A. Calin, P. Innelli, S. Yokoyama, C. Erol, P. Pabari, A. Tarr, M. Galderisi, S. Govind, B. Suran, I. Simova, E. Guyeli, T. Pinho, L. Bjornadal, B. Diaz Anton, J. Hilde, R. Sicari, C. Beladan, M. Ege, A. Zacharaki, L. Ghiadoni, A. A. La Huerta, S. Zdravkovic-Ciric, O. Huttin, K. Jensen-Urstad, F. Veglio, M. Elsedi, M. Nakabachi, P. Zinzius, D. Kim, H. Dores, A. Kakkavas, H. Badran, V. Sanchez Sanchez, E. Duo, J. Carrasco, A. Almeida, M. Virdee, M. Llemit, A. Anwar, L. Pratali, J. Monmeneu Menadas, S. Nevin, L. Fusini, F. Lombera Romero, E. Despotopoulos, E. Nyktari, G. Galanti, K. Kim, A. Van Der Hulst, H. Khachab, M. Dikic, I. Cruz, M. Melsom, J. Brugada, V. Mitic, M. Landolina, S. Turhan, V. Hansteen, D Rodriguez Munoz, J. S. De Lezo, N. Gori, Z. Baricevic, S.-P. Lee, M. Arnau Vives, S. Lee, P. Gripari, S. Humerfelt, F. Huang, T. Mikami, G. Soltan, T. Akasaka, S. Kaga, G. Penney, L. Toncelli, K. Boman, B. Basnyat, E. Kowalik, A. Bartolini, S. Georgiev, K. Shahgaldi, M. Pepi, M. Ruiz Ortiz, R. Sant'anna, H. Tsutsui, P. A. Fernandez, G. Tempesti, S. Aytekin, H. Iwano, Y. Nosir, C. Raineri, J. Rasmunsson, S. Lasarov, P. Lopez Lereu, V. Persic, F. Khan, J. Hisdal, M. Gommidh, A. Alhagoly, E. Gerdts, M. Milicia, G. Rengo, K. Kimura, F. Hakansson, M. Morenate, P. Mitev, M. Yacoub, M. Satendra, B. Kusmierczyk-Droszcz, E. Romo, R. Jankovic-Tomasevic, A. Roest, J. Stepanovic, J. Schwartz, Z. Ashour, L. Klitsie, J. Giner Blasco, M. Delgado, P. Omede, S. Mayordomo Gomez, I. Paraskevaidis, J. L. Zamorano, N. Goodfield, E. Dores, S. Davies, N. Patrascu, D. Alexopoulos, L. Donate Bertolin, D. Stanojevic, E. Psathakis, M. Dobric, P. Trivilou, H. Sasmaz, A. Marinkovic, O. Mirea, G. Sieswerda, M. Maruyama, A. M. Maceira Gonzalez, T. I. Imanishi, A. Santoro, G. Festa, R. Coma Samartin, and V. Atanaskovic
Subjects: medicine.medical_specialty, Stenosis, business.industry, Internal medicine, Cardiology, medicine, Radiology, Nuclear Medicine and imaging, General Medicine, Session (computer science), Cardiology and Cardiovascular Medicine, business, medicine.disease
Published: 2012
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12. Poster Session 2: Thursday 8 December 2011, 14:00-18:00 * Location: Poster Area

Author: X. Luo, F. Fang, J. Sun, J. Xie, A. Lee, Q. Zhang, C. Yu, O. Breithardt, S. Schiessl, M. Schmid, M. Seltmann, L. Klinghammer, C. Zeissler, M. Kuechle, W. Daniel, M. Ege, U. Guray, Y. Guray, B. Demirkan, H. Kisacik, S.-E. Kim, J.-Y. Hong, J.-H. Lee, D.-G. Park, K.-R. Han, D.-J. Oh, O. Tufekcioglu, D. C. Cozma, C. Mornos, A. Ionac, L. Petrescu, C. Tutuianu, S. I. Dragulescu, L. Guimaraes, G. Tavares, A. Rodrigues, C. Nagamatsu, C. Fischer, M. Vieira, W. Oliveira, T. Wilberg, A. Cordovil, S. Morhy, D. Muraru, M. Peluso, L. Dal Bianco, M. Beraldo, E. Solda', M. Tuveri, U. Cucchini, A. Al Mamary, L. Badano, S. Iliceto, A. Pizzuti, B. Mabritto, C. Derosa, A. Tomasello, M. Rovere, I. Parrini, M. Conte, N. Lareva, A. Govorin, R. Cooper, J. Sharif, J. D. Somauroo, J. D. Hung, V. Porcelli, R. Skevington, A. Shahzad, S. Scott, P. Lindqvist, S. Soderberg, M. Gonzalez, E. Tossavainen, M. Henein, N. Nciri, H. Saad, S. Nawas, A. Ali, A. Youssufzay, A. Safi, S. Faruk, S. Yurdakul, V. Erdemir, Y. Tayyareci, O. Yildirimturk, K. Memic, V. Aytekin, M. Gurel, S. Aytekin, M. Przewlocka-Kosmala, M. Cielecka-Prynda, A. Mysiak, W. Kosmala, S. Pescariu, D. Cozma, A. Mornos, S. Dragulescu, N. Maurea, C. G. Tocchetti, C. Coppola, C. Quintavalle, D. Rea, A. Barbieri, G. Piscopo, C. Arra, G. Condorelli, R. Iaffaioli, H. Dalen, A. Thorstensen, H. Moelmen, H. Torp, A. Stoylen, D. Augustine, C. Basagiannis, J. Suttie, P. Cox, R. Aitzaz, A. Lewandowski, M. Lazdam, C. Holloway, H. Becher, P. Leeson, S. Radovanovic, A. Djokovic, B. Todic, M. Zdravkovic, M. Zaja-Simic, S. Banicevic, D. Lisulov-Popovic, M. Krotin, J. Grapsa, D. O'regan, D. Dawson, G. Durighel, L. Howard, J. Gibbs, P. Nihoyannopoulos, C. Tulunay Kaya, M. Kilickap, H. Kurklu, N. Ozbek, C. Koca, V. Kozluca, K. Esenboga, C. Erol, B. Kusmierczyk-Droszcz, E. Kowalik, J. Niewiadomska, P. Hoffman, M. Satendra, L. Sargento, S. Lopes, S. Longo, N. Lousada, R. Palma Reis, P. Chillo, A. Rieck, J. Lwakatare, J. Lutale, E. Gerdts, S. Bonapace, G. Molon, G. Targher, A. Rossi, L. Lanzoni, G. Canali, E. Campopiano, L. Zenari, L. Bertolini, E. Barbieri, K. Hristova, L. Vladiomirova-Kitova, T. Katova, F. Nikolov, P. Nikolov, S. Georgieva, I. Simova, V. Kostova, V. A. Kuznetsov, D. V. Krinochkin, P. A. Chandraratna, Y. A. Pak, E. H. Zakharova, A. V. Plusnin, M. V. Semukhin, E. A. Gorbatenko, E. I. Yaroslavskaya, G. Bedetti, L. Gargani, M. Scalese, C. Pizzi, R. Sicari, E. Picano, M. Reali, E. Canali, S. Cimino, M. Francone, M. Mancone, R. Scardala, F. Boccalini, Y. Hiramoto, A. Frustaci, L. Agati, K. Savino, A. Lilli, E. Bordoni, C. Riccini, G. Ambrosio, D. Silva, N. Cortez-Dias, P. Carrilho-Ferreira, C. Jorge, J. Silva-Marques, A. Magalhaes, L. Santos, S. Ribeiro, F. Pinto, A. Nunes Diogo, E. Kinova, N. Zlatareva, A. Goudev, C. Bonanad, M. Lopez-Lereu, J. Monmeneu, V. Bodi, J. Sanchis, J. Nunez, F. Chaustre, A. Llacer, D. Ermacora, D. Peluso, M. Di Lazzari, P. Meimoun, F. Elmkies, T. Benali, J. Boulanger, H. Zemir, J. Clerc, A. Luycx-Bore, M. S. Velasco Del Castillo, A. Cacicedo Fernandez De Bobadilla, J. Onaindia Gandarias, M. Telleria Arrieta, G. Zugazabeitia Irazabal, O. Quintana Raczka, I. Rodriguez Sanchez, A. Romero Pereiro, E. Laraudogoitia Zaldumbide, I. Lekuona Goya, B. Bonello, E. El Louali, V. Fouilloux, I. Kammache, C. Ovaert, B. Kreitmann, A. Fraisse, R. Migliore, M. Adaniya, M. Barranco, G. Miramont, H. Tamagusuku, A. Alassar, R. Sharma, A. Marciniak, O. Valencia, N. Abdulkareem, M. Jahangiri, N. Jander, R. Kienzle, C. Gohlke-Baerwolf, H. Gohlke, F.-J. Neumann, J. Minners, S. Valbuena, F. De Torres, T. Lopez, J. J. Gomez, G. Guzman, F. Dominguez, E. Refoyo, M. Moreno, J. L. Lopez-Sendon, R. Ancona, S. Comenale Pinto, P. Caso, G. Di Salvo, S. Severino, M. Cavallaro, R. Calabro, R. Enache, R. Piazza, A. Roman-Pognuz, B. Popescu, A. Calin, C. Beladan, F. Purcarea, G. Nicolosi, C. Ginghina, O. Savu, M. Rosca, R. Jurcut, M. Serban, L. Dorobantu, E. Donal, S. Mascle, C. Thebault, D. Veillard, H. Hamonic, A. Leguerrier, H. Corbineau, B. A. Popa, M. Diena, A. Bogdan, D. Benea, G. Lanzillo, V. Casati, E. Novelli, A. Popa, G. Cerin, F. Gual Capllonch, A. Teis, J. Lopez Ayerbe, E. Ferrer, N. Vallejo, E. Gomez Denia, A. Bayes Genis, S. Spethmann, S. Schattke, G. Baldenhofer, V. Stangl, M. Laule, G. Baumann, K. Stangl, F. Knebel, C. Labata, C. Garcia Alonso, F. Gual, R. Nunez Aragon, C. Sousa, A. I. Vasile, M. Dorobantu, C. Iorgulescu, S. Bogdan, D. Constantinescu, C. Caldararu, O. Tautu, R. Vatasescu, H. Badran, M. F. Elnoamany, M. Ayad, A. Elshereef, A. Farhan, Y. Nassar, M. Yacoub, J. Costabel, G. Avegliano, P. Elissamburu, J. Thierer, F. Castro, M. Huguet, A. Frangi, R. Ronderos, C. Prinz, F. Van Buuren, L. Faber, T. Bitter, N. Bogunovic, W. Burchert, D. Horstkotte, J. D. Kasprzak, A. Smialowski, T. Rudzinski, P. Lipiec, M. Krzeminska-Pakula, K. Wierzbowska-Drabik, E. Trzos, M. Kurpesa, H. Motoki, M. Hana, T. Marwick, K. Allan, M. Vazquez-Alvarez, C. Medrano Lopez, S. Granja Da Silva, C. Marcos, A. Rodriguez-Ogando, M. Alvarez, M. Camino, M. Centeno, E. Maroto, G. Feltes Guzman, V. Serra Tomas, O. Acevedo, A. Calli, M. Barba, G. Pintos, V. Valverde, J. Zamorano Gomez, M. Marchel, J. Kochanowski, R. Piatkowski, A. Madej, K. Filipiak, I. Hausmanowa-Petrusewicz, G. Opolski, E. Malev, E. Zemtsovsky, S. Reeva, E. Timofeev, A. Pshepiy, S. Mihaila, R. Rimbas, R. Mincu, R. Dulgheru, R. Mihaila, C. Badiu, M. Cinteza, D. Vinereanu, E. Lira, D. Lebihan, C. Monaco, M. Ruiz Ortiz, D. Mesa, M. Delgado, E. Romo, M. Pena, M. Puentes, M. Santisteban, A. Lopez Granados, J. Arizon Del Prado, J. Suarez De Lezo, W.-C. Tsai, J.-Y. Shih, T.-S. Huang, Y.-W. Liu, Y.-Y. Huang, L.-M. Tsai, E. Cho, K. Choi, B. Kwon, D. Kim, S. Jang, C. Park, H. Jung, H. Jeon, H. Youn, J. Kim, A. E. Rieck, D. Cramariuc, M. Lonnebakken, B. Lund, P. Moceri, D. Doyen, P. Cerboni, E. Ferrari, W. Li, S. Goncalves, G. Vinhais De Sousa, A. G. Almeida, C. Hernandez Garcia, A. De La Rosa Hernandez, E. Arroyo Ucar, P. Jorge Perez, A. Barragan Acea, J. Lacalzada Almeida, J. Jimenez Rivera, A. Duque Garcia, I. Laynez Cerdena, O. Arhipov, A. N. Sumin, L. Campens, M. Renard, B. Trachet, P. Segers, A. De Paepe, J. De Backer, J. A. Purvis, D. Sharma, S. M. Hughes, D. Marek, D. Vindis, E. Kocianova, M. Taborsky, H. Yoon, K. Kim, Y. Ahn, M. Chung, J. Cho, J. Kang, W. Rha, O. Ozcan, D. Sezgin Ozcan, B. Candemir, M. Aras, I. Dincer, R. Atak, L. Gianturco, M. Turiel, F. Atzeni, L. Tomasoni, E. Bruschi, O. Epis, P. Sarzi-Puttini, C. Aggeli, E. Poulidakis, I. Felekos, S. Sideris, P. Dilaveris, K. Gatzoulis, C. Stefanadis, N. Roszczyk, M. Sobczak, J. Peruga, R. Krecki, J. Kasprzak, K. Ishii, T. Suyama, K. Kataoka, A. Furukawa, T. Nagai, M. Maenaka, Y. Seino, F. Musca, B. De Chiara, A. Moreo, S. Cataldo, M. Parolini, O. Parodi, T. Bombardini, F. Faita, S.-J. Park, J.-H. Kil, S.-J. Kim, S.-Y. Jang, S.-A. Chang, J.-O. Choi, S.-C. Lee, S. Park, P. Park, J. Oh, M. Cikes, V. Velagic, B. Biocina, H. Gasparovic, Z. Djuric, B. Bijnens, D. Milicic, A. Huqi, B. Klas, A. He, I. Paterson, M. Irween, J. Ezekovitz, J. Choy, Y. Chen, L. Cheng, R. Yao, H. Yao, H. Chen, C. Pan, X. Shu, B. Sobkowicz, M. Kaminska, W. Musial, R. Buechel, G. Sommer, G. Leibundgut, A. Rohner, J. Bremerich, B. Kaufmann, A. Kessel-Schaefer, M. Handke, A. Kiotsekoglou, S. Saha, R. Toole, S. Sharma, A. Gopal, S. Adhya, W. Tsang, C. Kenny, S. Kapetanakis, R. Lang, M. Monaghan, B. Smith, T. Coulter, A. Rendon, W.-S. Cheung, W. Gorissen, J. A. Ejlersen, O. May, F. J. Van Slochteren, T. Van Der Spoel, H. Hanssen, P. Doevendans, S. Chamuleau, C. De Korte, A. Tarr, S. Stoebe, T. Trache, J.-G. Kluge, A. Varga, A. Hagendorff, A. Nagy, A. Kovacs, A. Apor, B. Sax, D. Becker, B. Merkely, R. Lindquist, A. Miller, C. Reece, B. W. Eidem, W.-G. Choi, S. Kim, S. Oh, Y. Kim, R. Iacobelli, M. Chinali, M. D' Asaro, A. Toscano, A. Del Pasqua, C. Esposito, G. Seghetti, F. Parisi, G. Pongiglione, G. Rinelli, O. Omaygenc, R. Bakal, C. Dogan, K. Teber, S. Akpinar, G. Sahin, N. Ozdemir, A. Penhall, M. Joseph, F. Chong, C. De Pasquale, J. Selvanayagam, D. Leong, E. G. Nyktari, A. P. Patrianakos, C. Goudis, G. Solidakis, F. Parthenakis, P. Vardas, E. Nestaas, D. Fugelseth, A. Vitarelli, L. Capotosto, M. Bernardi, Y. Conde, F. Caranci, G. Placanica, O. Dettori, M. Vitarelli, S. De Chiara, V. De Cicco, M. Ferro', R. Calabro', S. Apostolakis, G. Chalikias, D. Tziakas, D. Stakos, A. Thomaidi, S. Konstantinides, G. Iorio, R. Rucos, G. Continanza, M. D Ascanio, L. Alessandroni, M. Saponara, M. Berry, J. Nahum, O. Zaghden, J. Monin, J. Couetil, O. Lairez, L. Macron, J. Dubois Rande, P. Gueret, P. Lim, M. Cameli, E. Giacomin, M. Lisi, S. Benincasa, F. Righini, D. Menci, M. Focardi, S. Mondillo, E. Philip, G. Gorincour, H. Bellsham-Revell, A. J. Bell, O. I. Miller, P. Beerbaum, R. Razavi, G. Greil, J. M. Simpson, S. Ann, T. Kim, J. Lee, J. Chin, P. Cabeza Lainez, V. Escolar Camas, L. Gheorghe, P. Fernandez Garcia, R. Vazquez Garcia, V. Caiulo, S. Caiulo, A. Fisicaro, F. Moramarco, G. Latini, A. Seale, J. Carvalho, H. Gardiner, M. Roughton, J. Simpson, A. Tometzki, O. Uzun, S. Webber, P. Daubeney, A. Dawood, G. Dwivedi, G. Mahadevan, D. Jiminez, R. Steeds, M. Frenneaux, C. H. Attenhofer Jost, B. Knechtle, A. Bernheim, M. Pfyffer, A. Linka, A. Faeh-Gunz, B. Seifert, G. De Pasquale, M. Zuber, A. Tomaszewski, A. Kutarski, and M. Tomaszewski
Subjects: Computer science, Plane (geometry), business.industry, Echo (computing), Left atrium, General Medicine, Biplane, medicine.anatomical_structure, Software, Left atrial, medicine, Radiology, Nuclear Medicine and imaging, Cardiology and Cardiovascular Medicine, business, Nuclear medicine
Published: 2011
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13. MODERATED POSTER SESSION: Diseases impact on left ventricular function: Friday 5 December 2014, 08:30-18:00 * Location: Moderated Poster area

Author: J. Ternacle, G. Pedrizzetti, M. Maciel, M. Trivigno, S.O Rosillo Rodriguez, A. Milan, A. Ravera, T. Lopez Fernandez, A. Guellich, L. Hittinger, I. Ponz De Antonio, D. Bodez, J. Silva-Cardoso, Z. Friedman, J. Rodrigues, I. Rangel, F. Cicogna, F. Macedo, A. Kremzer, J.-L. Dubois-Rande, M. De Buyzere, D. Projevska-Donegati, E. Zemtsovsky, M. Omelchenko, E. Avenatti, V. Milazzo, Payman Zamani, D. Leone, D. Cantisani, V. Plante-Bordeneuve, C.-M. Tissot, P. Almeida, Dirk De Bacquer, F. Veglio, Thierry C. Gillebert, N. Smirin, Z. Blazquez Bermejo, S. Shimoni, J.-F. Deux, L. Sabia, A. Goncalves, Ernst Rietzschel, S. Rappeneau, Prithvi Shiva-Kumar, M. Moreno Yanguela, T. Damy, L. Georgievska-Ismail, S. Cimino, R. Mori Junco, T. Berezina, Julio A. Chirinos, C. Sousa, L. Agati, A. Fabbri, D. Adam, J Caro Codon, A. Hagendorff, Z. Hristovski, Tom Claessens, Patrick Segers, L. Vasina, G. Tonti, Scott Akers, J. Lopez-Sendon, E. Malev, F. Tosello, C. Caira, D. Gemma, T. Samura, G. Bruno, A. Berezin, H. Khamis, and S. Valbuena
Subjects: medicine.medical_specialty, Ventricular function, business.industry, Physical therapy, medicine, Radiology, Nuclear Medicine and imaging, General Medicine, Session (computer science), Cardiology and Cardiovascular Medicine, business
Published: 2014
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14. Oral Abstract Session * New insights into primary mitral regurgitation: Valvular heart disease associated with systemic conditions and others

Author: E. Malev, E. Zemtsovsky, T. Zhelninova, O. Dubrovskaya, M. Perevoznikova, M. Rudakov, E. Luneva, L. Khaletskaya, E. Shlyakhto, J. Magne, H. Mahjoub, P. Pibarot, Z. Elhonsali, R. Dulgheru, P. Lancellotti, L. Pierard, J. Bologne, M. Cameli, M. Lisi, F. Righini, A. Massoni, B. Natali, D. Tacchini, M. Maccherini, M. Chiavarelli, M. Massetti, S. Mondillo, T. Le Tourneau, G. Deswartes, M. Richardson, C. Foucher, A. Polge, G. Fayad, A. Vincentelli, N. Lamblin, J. Trochu, and C. Bauters
Subjects: medicine.medical_specialty, Mitral regurgitation, business.industry, Internal medicine, valvular heart disease, Cardiology, Medicine, Radiology, Nuclear Medicine and imaging, General Medicine, Session (computer science), Cardiology and Cardiovascular Medicine, business, medicine.disease
Published: 2012
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15. P100Angiotensin II receptor blockers in modulation of transforming growth factor-b cardiac effects in mitral valve prolapse

Author: G Kim, L Vasina, M Omelchenko, E. Malev, and E. Zemtsovsky
Subjects: Mitral regurgitation, Mitral valve repair, medicine.medical_specialty, Ejection fraction, Physiology, business.industry, medicine.medical_treatment, medicine.disease, Myxomatous degeneration, Blood pressure, medicine.anatomical_structure, Physiology (medical), Mitral valve, Internal medicine, medicine, Cardiology, Mitral valve prolapse, Systole, Cardiology and Cardiovascular Medicine, business
Abstract: Purpose: The inhibition by angiotensin II receptor blockers (ARB) the transforming growth factor-b (TGF-b) induced extracellular matrix production has been shown recently in cultured valvular interstitial cells obtained from patients with mitral valve prolapse (MVP) undergoing mitral valve repair. Our aim was to evaluate the effect of ARB therapy on TGF-b serum level and possible impact on valve myxomatous degeneration and left ventricular (LV) systolic dysfunction in MVP patients. Methods: A total of 233 asymptomatic patients (mean age: 53.8±12.9) with severe mitral regurgitation (MR) due to mitral valve prolapse were enrolled in our retrospective, non-randomized, single-center study between 2009 and 2011. Concentrations of TGF-b1 and b2 in serum were determined by enzyme-linked immunosorbent assay (Bender MedSystems). Standard echocardiography extended with speckle-tracking echocardiography was performed in all patients (EchoPAC'08, GE). Results: According to the case reports only 43 (18.5%) patients received losartan or telmisartan (study group). Majority of the patients (190, 81.5%) did not receive any ARBs (control group). There were no significant differences between groups in age, other medical treatment (β-blockers, diuretics), heart rate and blood pressure. Mitral regurgitation had the similar effective regurgitant orifice area (0.38±0.12 vs. 0.40±0.14 sm2; p=0.38) and volume (69.5±9.8 vs. 72.3±8.6 ml; p=0.08) by PISA in both groups. TGF-b1 level was significantly higher in subjects without ARB therapy (55.9±70.7 ng/ml) than in ARB group (16.1±32.9 ng/ml; p=0.0003), as well TGF-b2 (7.6±0.5 vs. 2.2±1.5 ng/ml; p
Published: 2014
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16. Medial degenerative disease and atherosclerosis in bicuspid and tricuspid aortic valve-associated thoracic aortic aneurysm

Author: Lubov Mitrofanova, E. Zemtsovsky, E. Malev, E.B. Luneva, V. Uspensky, and M. Paydimirova
Subjects: Aortic valve, Aortic atherosclerosis, Aorta, medicine.medical_specialty, Degenerative Disorder, business.industry, medicine.disease, Thoracic aortic aneurysm, Surgery, medicine.anatomical_structure, Degenerative disease, Aneurysm, medicine.artery, Internal medicine, Ascending aorta, medicine, Cardiology, Cardiology and Cardiovascular Medicine, business
Published: 2013
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17. Echocardiographic and biochemical predictors of ventricular arrhythmias in young patients with mitral valve prolapse

Author: A.L. Korshunova, E. Zemtsovsky, Eugeny Timofeev, Svetlana V. Reeva, E. Malev, and A. Pshepiy
Subjects: medicine.medical_specialty, Mitral regurgitation, Ejection fraction, business.industry, medicine.disease, Asymptomatic, Contractility, Parasternal line, Fibrosis, Internal medicine, cardiovascular system, medicine, Cardiology, Mitral valve prolapse, Sinus rhythm, cardiovascular diseases, medicine.symptom, Cardiology and Cardiovascular Medicine, business
Abstract: Purpose: Ventricular arrhythmias are known to be common in symptomatic patients with Mitral Valve Prolapse (MVP). The aim of our study was to investigate the prevalence, echocardiographic and biochemical predictors, and possible mechanisms of ventricular arrhythmias in young asymptomatic patients with MVP without significant mitral regurgitation. Methods: We studied 78 asymptomatic young subjects (mean age 19.7±1.6, 72% male) in sinus rhythm with MVP in comparison with 80 sex- and age-matched healthy subjects. Transthoracic echocardiography (Vivid 7 Dimension, GE) and 24-hour Holter monitoring were performed. MVP was diagnosed by billowing of 1 or both mitral leaflets >2 mm above the mitral annulus in the long-axis parasternal view. Longitudinal strain were determined from three apical views, using spackle tracking (EchoPAC'08, GE) with grey-scale frame rate 50-55/sec. Concentration of Monocyte Chemoattractant Protein-1 (MCP-1) in serum were determined by enzyme-linked immunosorbent assay. Results: The frequency of isolated Ventricular Premature Contractions (VPCs) was similar in both groups (32.4% and 33.3%; χ2=1.2, p=0.90). Ventricular tachycardias were not found in either MVP nor in control group. However, the ventricular couplets were recorded only in patients with MVP (in 8.1% of MVP group; χ2=5.2, p=0.01). The presence of couplets negatively correlated with Left Ventricular (LV) ejection fraction (r=–0.66; p=0.0001), with a global LV longitudinal strain (r=–0.78; p
Published: 2013
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18. ASSOCIATION OF HEART AND VASCULAR DAMAGE IN SUBJECTS WITH CARDIOMETABOLIC RISK FACTORS

Author: V. Ivanenko, A. Erina, E. Sokalskaya, V. Solntsev, N. Dzubenko, E. Kolesova, O. Dubrovskaya, O. P. Rotar, E. Malev, E. Moguchaya, EV Litvinenko, and A.O. Konradi
Subjects: Cardiometabolic risk, medicine.medical_specialty, Physiology, business.industry, Internal medicine, Internal Medicine, medicine, Cardiology and Cardiovascular Medicine, business, Association (psychology)
Published: 2011
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19. Changes in the Respiratory Quotient Produced by Subcutaneous Injection of Dioxyacetone and Glucose

Author: M. E. Malev, H. E. Himwich, and M. I. Rose
Subjects: medicine.medical_specialty, Sucrose, Chemistry, General Biochemistry, Genetics and Molecular Biology, Surgery, law.invention, Respiratory quotient, Subcutaneous injection, Expired air, chemistry.chemical_compound, law, Anesthesia, medicine, Warm water, Spirometer
Abstract: Evidence on the availability of dioxyacetone and glucose by the animal organism has led to opposing conclusions. Rabinowitch1 and Mason2 have found that dioxyacetone is more readily oxidized than glucose. Ringer and Frankel3 have shown that in diabetic dogs dioxyacetone is synthesized to glucose. Campbell, Fletcher, Hepburn and Markowitz,4 obtaining similar results, concluded that dioxyacetone presents no advantage to the organism, since it must be converted to glucose, prior to oxidation. In the present experiments the availability of these two substances has been studied after subcutaneous injection.Fifteen experiments were performed on a trained dog, in which 10 grams of the substance studied, dissolved in 10 cc. of warm water, were injected subcutaneously. Seven experiments were performed using dioxyacetone, seven using glucose, and one employing sucrose. The dog had been trained to lie quietly with a leak-proof mask on its head, the expired air being collected through Sadd valves into a spirometer. A...
Published: 1926
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20. Assessment of the effectiveness of weight-adjusted antibiotic administration, for reduced duration, in surgical prophylaxis of primary hip and knee arthroplasty.

Author: Okoro T, Wan M, Mukabeta TD, Malev E, Gross M, Williams C, Manjra M, Kuiper JH, and Murnaghan J
Abstract: Background: Prophylactic antibiotics have significantly led to a reduction in the risk of post-operative surgical site infections (SSI) in orthopaedic surgery. The aim of using antibiotics for this purpose is to achieve serum and tissue drug levels that exceed, for the duration of the operation, the minimum inhibitory concentration of the likely organisms that are encountered. Prophylactic antibiotics reduce the rate of SSIs in lower limb arthroplasty from between 4% and 8% to between 1% and 3%. Controversy, however, still surrounds the optimal frequency and dosing of antibiotic administration., Aim: To evaluate the impact of introduction of a weight-adjusted antibiotic prophylaxis regime, combined with a reduction in the duration of administration of post-operative antibiotics on SSI incidence during the 2 years following primary elective total hip and knee arthroplasty., Methods: Following ethical approval, patients undergoing primary total hip arthroplasty (THA)/total knee arthroplasty (TKA) with the old regime (OR) of a preoperative dose [cefazolin 2 g intravenously (IV)], and two subsequent doses (2 h and 8 h), were compared to those after a change to a new regime (NR) of a weight-adjusted preoperative dose (cefazolin 2 g IV for patients < 120 kg; cefazolin 3g IV for patients > 120 kg) and a post-operative dose at 2 h. The primary outcome in both groups was SSI rates during the 2 years post-operatively., Results: A total of n = 1273 operations (THA n = 534, TKA n = 739) were performed in n = 1264 patients. There was no statistically significant difference in the rate of deep (OR 0.74% (5/675) vs NR 0.50% (3/598); fishers exact test P = 0.72), nor superficial SSIs (OR 2.07% (14/675) vs NR 1.50% (9/598); chi-squared test P = 0.44) at 2 years post-operatively. With propensity score weighting and an interrupted time series analysis, there was also no difference in SSI rates between both groups [RR 0.88 (95%CI 0.61 to 1.30) P = 0.46]., Conclusion: A weight-adjusted regime, with a reduction in number of post-operative doses had no adverse impact on SSI incidence in this population., Competing Interests: Conflict-of-interest statement: All the authors have no conflict of interest to declare., (©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.)
Published: 2024
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21. Prediction of Aortic Stenosis Progression by 18 F-FDG and 18 F-NaF PET/CT in Different Aortic Valve Phenotypes.

Author: Murtazalieva P, Ryzhkova D, Malev E, Zhiduleva E, and Moiseeva O
Abstract: Background: Different imaging techniques, such as echocardiography (ECHO) and CT, allow to assess aortic stenosis (AS) severity and could be used to study its progression. But only PET/CT open opportunities to assess activity of valvular inflammation and calcification in vivo . The aim of this study was to assess prognostic value of valvular inflammation and calcification measured by 18 F-FDG and 18 F-NaF PET/CT in patients with tricuspid (TAV) and bicuspid aortic valve (BAV). Methods: The study included 71 patients aged 40-70 years with mild, moderate and severe asymptomatic calcific AS. Patients were divided into two groups according to valve morphology: with BAV and TAV. All patients underwent standard ECHO, CT calcium scoring PET/CT with 18 F-NaF and 18 F-FDG. All patients were evaluated during a follow-up visit with evaluation of ECHO parameters. (16.8 ± 4.2 months). Results: TAV and BAV groups were comparable in AS severity by ECHO (peak aortic jet velocity (Vmax): 2.90 [2.60; 3.50] vs. 2.96 [2.55; 3.31] m/s, p = 0.83). TBR max 18 F-FDG did not vary in TAV and BAV patients (1.15 [1.06; 1.23] vs. 1.11 [1.03; 1.20], p = 0.39). Both groups did not differ in valvular calcification degree (Agatston score 1,058 [440; 1798] vs. 1,128 [533; 2,360], p = 0.55) and calcification activity assessed by 18 F-NaF uptake level (TBR max 1.50 [1.30; 1.78] vs. 1.48 [1.27; 1.83], p = 0.97). 18 F-NaF TBR max was associated with AS severity measured by Vmax in men and women with TAV (r = 0.54; p = 0.04 vs. r = 0.53; p = 0.03). In BAV group this relationship was true only in female patients (r = 0.1; p = 0.67 vs. r = 0.7; p = 0.0004). There was no association between Vmax and TBR max 18 F-FDG was revealed in TAV and BAV groups. During follow-up period, the most important positive predictors of AS progression in TAV obtained by multinomial logistic regression analysis were Vmax, and 18 F-NaF TBR. Whereas in BAV the highest predictive value showed model included age and Vmax. Conclusion: 18 F-NaF PET/CT may be considered as the valuable predictor for hemodynamic progression of calcific AS in case of TAV. 18 F-FDG PET/CT does not play a significant role to predict the AS progression., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2022 Murtazalieva, Ryzhkova, Malev, Zhiduleva and Moiseeva.)
Published: 2022
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22. Thrombin generation test for evaluation of antiplatelet treatment in patients with coronary artery disease after percutaneous coronary intervention.

Author: Berezovskaya G, Smirnova O, Malev E, Khromov-Borisov N, Klokova E, Karpenko M, Papayan L, and Petrishchev N
Subjects: Aged, Coronary Artery Disease blood, Coronary Artery Disease drug therapy, Female, Humans, Male, Middle Aged, Percutaneous Coronary Intervention methods, Platelet Aggregation Inhibitors pharmacology, Thrombin pharmacology, Coronary Artery Disease etiology, Percutaneous Coronary Intervention adverse effects, Platelet Aggregation Inhibitors therapeutic use, Thrombin therapeutic use
Abstract: To study the possibility of using thrombin generation tests in platelet-rich and platelet-poor plasma for evaluation of dual antiplatelet therapy efficacy in patients with coronary artery disease (CAD), following percutaneous coronary intervention. Venous blood was analyzed from CAD patients aged 53-75 years who had undergone percutaneous coronary intervention with stenting within one year and had been receiving standard doses of clopidogrel and aspirin (75 and 75-100 mg per day, respectively). The control group comprised age- and sex-matched subjects without clinical signs of CAD who were not receiving these drugs. Thrombin generation tests were performed in platelet-rich and platelet-poor plasma. Intravascular platelet activation, induced platelet aggregation, and routine coagulation were evaluated. Antiplatelet treatment did not influence results of routine coagulation tests or intravascular platelet activation. The dual antiplatelet therapy affects collagen-induced platelet aggregation (44 ± 2.5 vs. 7.9 ± 2.6%, р = 10 -7 ) and leads to decreases in endogenous thrombin potential (1900 ± 85 vs. 1740 ± 95 nM∙min, p = 0.0045), maximum thrombin concentration (134 ± 9.5 vs. 106 ± 6.5 nM, p = 4∙10 -6 ), and increases in time to peak thrombin (27 ± 1.5 vs. 31 ± 2 min, p = 0.0012). Decreases in thrombin generation rate showed the highest statistical significance (13 ± 2 vs. 7.9 ± 0.8 nM/min, p = 10 -8 ). Antiplatelet treatment did not alter thrombogram parameters for platelet-poor plasma.
Published: 2018
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23. Mitral valve prolapse and left ventricular systolic function.

Author: Malev E and Zemtsovsky E
Subjects: Female, Humans, Male, Ultrasonography, Cardiomyopathies diagnostic imaging, Mitral Valve Prolapse diagnostic imaging, Transforming Growth Factor beta1 blood, Transforming Growth Factor beta2 blood
Published: 2015
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24. Rare Case of Vaginal Delivery in Giant Aortic Aneurysm.

Author: Luneva E, Samokhvalova M, Pakhomov A, Mitrofanova L, Malev E, and Uspenskiy V
Abstract: A 33-year-old woman underwent successful vaginal delivery despite previously unsuspected 8-cm ascending and 6-cm descending aortic aneurysms. These were repaired immediately after delivery.
Published: 2015
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25. Cardiomyopathy in young adults with classic mitral valve prolapse.

Author: Malev E, Reeva S, Vasina L, Timofeev E, Pshepiy A, Korshunova A, Prokudina M, and Zemtsovsky E
Subjects: Adolescent, Cardiomyopathies blood, Cardiomyopathies complications, Case-Control Studies, Echocardiography, Enzyme-Linked Immunosorbent Assay, Female, Humans, Male, Mitral Valve Prolapse blood, Mitral Valve Prolapse complications, Young Adult, Cardiomyopathies diagnostic imaging, Mitral Valve Prolapse diagnostic imaging, Transforming Growth Factor beta1 blood, Transforming Growth Factor beta2 blood
Abstract: Background: In some inherited connective tissue diseases with involvement of the cardiovascular system, for example, Marfan syndrome, early impairment of left ventricular function, which have been described as Marfan-related cardiomyopathy has been reported. Our aim was to evaluate the left ventricular function in young adults with mitral valve prolapse without significant mitral regurgitation using two-dimensional strain imaging and to determine the possible role of the transforming growth factor-β pathway in its deterioration., Methods: We studied 78 young adults with mitral valve prolapse without mitral regurgitation in comparison with 80 sex-matched and age-matched healthy individuals. Longitudinal strain and strain rates were defined using spackle tracking. Concentrations of transforming growth factor-β₁ and β₂ in serum were determined by enzyme-linked immunosorbent assays., Results: In 29 patients, classic relapse was identified with a leaflet thickness of ≥ 5 mm; 49 patients had a non-classic mitral valve prolapse. Despite the similar global systolic function, a significant reduction in global strain was found in the classic group (-15.5 ± 2.9%) compared with the non-classic group (-18.7 ± 3.8; p = 0.0002) and the control group (-19.6 ± 3.4%; p < 0.0001). In young adults with non-classic prolapse, a reduction in longitudinal deformation was detected only in septal segments. Transforming growth factor-β₁ and β₂ serum levels were elevated in patients with classic prolapse as compared with the control group and the non-classic mitral valve prolapse group., Conclusions: These changes in the deformations may be the first signs of deterioration of the left ventricular function and the existence of primary cardiomyopathy in young adults with mitral valve prolapse, which may be caused by increased transforming growth factor-β signalling.
Published: 2014
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26. Preoperative left ventricular function in degenerative mitral valve disease.

Author: Malev E, Kim G, Mitrofanova L, and Zemtsovsky E
Subjects: Adult, Aged, Female, Genetic Diseases, X-Linked diagnostic imaging, Genetic Diseases, X-Linked pathology, Genetic Diseases, X-Linked surgery, Humans, Male, Middle Aged, Mitral Valve Insufficiency diagnostic imaging, Mitral Valve Insufficiency pathology, Mitral Valve Insufficiency surgery, Mitral Valve Prolapse diagnostic imaging, Mitral Valve Prolapse pathology, Mitral Valve Prolapse surgery, Observer Variation, Preoperative Period, Prognosis, Retrospective Studies, Stroke Volume physiology, Ultrasonography, Genetic Diseases, X-Linked physiopathology, Mitral Valve Insufficiency physiopathology, Mitral Valve Prolapse physiopathology, Ventricular Function, Left physiology
Abstract: Aim: The aim of the study is to determine the impact of the underlying etiology (Barlow's disease or fibroelastic deficiency) on left ventricular function in patients with degenerative mitral valve disease and severe mitral regurgitation., Methods: We studied 233 patients (mean age: 53.8 ± 12.9) undergoing surgery for severe mitral regurgitation due to degenerative mitral valve disease at Almazov Federal Heart Centre between 2009 and 2011. Pathologic diagnoses for valvular tissue specimens were provided by an experienced pathologist. Preoperative strain and strain rate were determined using speckle tracking (Vivid 7 Dimension, EchoPAC'08)., Results: Barlow's disease was identified by the pathologist in 60 patients (25.8%), and fibroelastic deficiency in 173 patients (74.2%). There were no significant differences between groups in preoperative mitral regurgitation volume (70.5 ± 9.6 vs. 71.6 ± 8.5 ml, P = 0.40), and in global systolic (ejection fraction: 52.7 ± 6.6 vs. 52.0 ± 7.4%, P = 0.53) and diastolic (E/e': 12.2 ± 3.9 vs. 12.8 ± 4.2, P = 0.35) left ventricular function. Despite the lack of difference in ejection fraction and diastolic tissue Doppler parameters, in patients with Barlow's disease in comparison with fibroelastic deficiency a significant decrease of the left ventricular longitudinal systolic strain (-13.5 ± 2.2 vs. -15.6 ± 2.3%, P = 0.00001) and early diastolic strain rate (1.04 ± 0.20 vs. 1.14 ± 0.18 s, P = 0.0004) were detected., Conclusion: Patients with severe mitral regurgitation due to Barlow's disease have a lower preoperative left ventricular systolic function than those with fibroelastic deficiency, which may affect their postoperative prognosis.
Published: 2014
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27. Giant syphilitic aortic aneurysm.

Author: Luneva E, Malev E, Rizhkov A, and Pakhomov A
Subjects: Aortic Aneurysm, Thoracic diagnosis, Dyspnea diagnosis, Dyspnea microbiology, Humans, Male, Middle Aged, Syphilis, Cardiovascular diagnosis
Published: 2014
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28. Evaluation of left ventricular systolic function in young adults with mitral valve prolapse.

Author: Malev E, Zemtsovsky E, Pshepiy A, Timofeev E, Reeva S, and Prokudina M
Abstract: Objective: To evaluate left ventricular function in young adults with mitral valve prolapse (MVP) without significant mitral regurgitation using two-dimensional strain imaging., Methods and Results: A total of 58 asymptomatic young subjects (mean [± SD] age 19.7±1.6 years; 72% male) with MVP were compared with 60 sex- and age-matched healthy subjects. MVP was diagnosed by billowing one or both mitral leaflets >2 mm above the mitral annulus in the long-axis parasternal view. Longitudinal, radial and circumferential strain and strain rate were determined using speckle tracking with a grey-scale frame rate of 50 fps to 85 fps. There were no significant differences in the global systolic left ventricular function of the subjects with MVP compared with the control group. In the MVP group, most of the global myocardial systolic deformation indexes were not reduced. Only the global circumferential strain showed a decrease in the prolapse subjects. Regional, longitudinal, circumferential and radial strain and strain rate were decreased only in septal segments. A decrease in the rotation of the same septal segments at the basal level was also observed., Conclusion: Regional septal myocardial deformation indexes decrease in subjects with MVP. These changes may be the first sign indicating the deterioration of left ventricular systolic function as well as the existence of primary cardiomyopathy in asymptomatic young subjects with MVP.
Published: 2012

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28 results on '"E. Malev"'

1. Midventricular obstruction and left ventricular remodeling after transcatheter aortic valve implantation

2. The influence of afterload on left ventricular contractility: 2D-strain and dyssynchrony in stress echocardiography

3. Global longitudinal strain and left ventricle dyssynchrony changes during stress echocardiography in response to antihypertensive treatment optimization

4. P5578Integrated approach in assessment of valvular calcification activity in aortic stenosis

5. P4483Transforming growth factor-beta and arrhythmias in mitral valve prolapse patients

6. P725Effect of renin-angiotensin system blockade in prevention of thoracic aortic aneurysm progression

7. 2462PET/CT with 18F-sodium fluoride in patients with aortic stenosis and different aortic valve morphology

9. P1643Calcification and inflammation in aortic stenosis - are the mechanisms in tricuspid and bicuspid aortic valve different?

10. Poster session Friday 13 December - PM: 13/12/2013, 14:00-18:00 * Location: Poster area

11. Poster session: Aortic stenosis

12. Poster Session 2: Thursday 8 December 2011, 14:00-18:00 * Location: Poster Area

13. MODERATED POSTER SESSION: Diseases impact on left ventricular function: Friday 5 December 2014, 08:30-18:00 * Location: Moderated Poster area

14. Oral Abstract Session * New insights into primary mitral regurgitation: Valvular heart disease associated with systemic conditions and others

15. P100Angiotensin II receptor blockers in modulation of transforming growth factor-b cardiac effects in mitral valve prolapse

16. Medial degenerative disease and atherosclerosis in bicuspid and tricuspid aortic valve-associated thoracic aortic aneurysm

17. Echocardiographic and biochemical predictors of ventricular arrhythmias in young patients with mitral valve prolapse

18. ASSOCIATION OF HEART AND VASCULAR DAMAGE IN SUBJECTS WITH CARDIOMETABOLIC RISK FACTORS

19. Changes in the Respiratory Quotient Produced by Subcutaneous Injection of Dioxyacetone and Glucose

20. Assessment of the effectiveness of weight-adjusted antibiotic administration, for reduced duration, in surgical prophylaxis of primary hip and knee arthroplasty.

21. Prediction of Aortic Stenosis Progression by 18 F-FDG and 18 F-NaF PET/CT in Different Aortic Valve Phenotypes.

22. Thrombin generation test for evaluation of antiplatelet treatment in patients with coronary artery disease after percutaneous coronary intervention.

23. Mitral valve prolapse and left ventricular systolic function.

24. Rare Case of Vaginal Delivery in Giant Aortic Aneurysm.

25. Cardiomyopathy in young adults with classic mitral valve prolapse.

26. Preoperative left ventricular function in degenerative mitral valve disease.

27. Giant syphilitic aortic aneurysm.

28. Evaluation of left ventricular systolic function in young adults with mitral valve prolapse.

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