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Previous studies of auditory imagery have often confounded vividness and clarity, and the differences between these constructs are not clear. Additionally, it has been suggested that clarity is a more useful construct than is vividness in understanding auditory imagery. The Clarity of Auditory Imagery Scale and the Bucknell Auditory Imagery Scale were administered to participants, and ratings of the clarity, vividness, and control over auditory imagery were collected. All three measures were highly positively correlated. The magnitudes of these correlations were not influenced by participants’ sex, age, ethnic group, handedness, years of participation in a band or choir, or years of formal instruction in music, and possible reasons for the lack of individual differences are discussed. Three analogies for understanding differences between vividness in auditory imagery and clarity in auditory imagery, and suggestions for potential operational definitions of auditory vividness and auditory clarity in future studies, are provided.

ZusammenfassungSchleimhautmelanome sind seltene Formen von Melanomen mit einer ungünstigen Prognose. Bei Fehlen von therapierelevanten Mutationen und Inoperabilität stellt die Therapie mit Immuncheckpoint-Inhibitoren eine aussichtsreiche Option dar. Die Kombination aus dem PD-1-Antikörper Nivolumab und dem CTLA4-Antikörper Ipilimumab ist effektiver, jedoch auch erheblich toxischer als die Monotherapie mit PD-1-Antikörpern. Wir berichten über eine 57-jährige Patientin mit einem lymphogen metastasierten inoperablen Gingivamelanom im Stadium IIID, die mit einer Kombination aus Nivolumab und Ipilimumab behandelt wurde und hierunter multiple autoimmunvermittelte Nebenwirkungen einschließlich eines Schubs einer rheumatoiden Arthritis, einer Autoimmunkolitis, einer Autoimmunthyreoiditis und einer Autoimmunhepatitis entwickelte. Diese konnten mithilfe von systemischen Steroiden und symptomatischer Therapie beherrscht werden und es konnte eine anhaltende partielle Remission bei guter Lebensqualität erzielt werden. Unser Fall liefert ein Beispiel für den erfolgreichen Einsatz von Immuncheckpoint-Inhibitoren bei seltenen Melanom-Entitäten, veranschaulicht jedoch auch die Bedeutung von intensivem Monitoring besonders bei Patienten mit zugrunde liegenden Autoimmunerkrankungen.

In an effort to improve the training of future child protection professionals, more than 70 universities and graduate schools in the United States have implemented Child Advocacy Studies (CAST) minors or graduate programs. In order to assess the efficacy of these programs, 46 current and recent graduates of a CAST minor and 43 child protection professionals currently employed by a Department of Social Services (DSS) were given two vignettes. The first vignette involved a clear case of sexual abuse and the second vignette involved a more complex case involving polyvictimization. The students were asked to identify various systems that needed to be involved, potential corroborating evidence, risk and protective factors, and types of victimization. In the case of sexual abuse, the current CAST students and CAST graduates performed at the same level as DSS caseworkers. On the more complex polyvictimization scenario, the current CAST students and CAST graduates performed significantly better than all levels of DSS caseworkers in identifying systems that respond to child maltreatment and in identifying psychological and emotional abuse. The results of this study suggests that undergraduate CAST minors may be an effective model for improving the knowledge and skills of future child protection professionals in responding to complex cases of maltreatment.

Observers viewed modified launching effect displays containing a spatial gap between the final location of the launcher (a black square) and the initial location of the target (a black outl...

Ratings of perceived force and ratings of perceived causality were obtained for stimuli in which an initially moving object contacted an initially stationary object, and upon contact (1) the initially moving object became stationary or shattered into four or nine fragments and (2) the initially stationary object remained stationary, was launched into motion, or shattered into four or nine fragments. Implied motion rather than smooth or continuous motion was presented. The initially moving object was rated as more causal and as exerting more force if upon contact the initially stationary object was launched into motion or shattered, but the initially stationary object was rated as more causal and as exerting more force if upon contact the initially moving object stopped or shattered (and the initially stationary object remained stationary and intact). An object that did not shatter or that shattered into fewer fragments was rated as more causal and as exerting more force than an object that shattered into ...

Memory for the initial pitch of an auditory target that increased or decreased in auditory frequency was examined. Memory was displaced forward in the direction of pitch motion, and this is consistent with the Fröhlich effect previously observed for visual targets moving in visual physical space. The Fröhlich effect for pitch increased with faster target velocity and decreased if an auditory cue with the same pitch as the initial pitch of the target was presented before the target was presented. The Fröhlich effect was larger for descending pitch motion than for ascending pitch motion, and this is consistent with an influence of representational gravity. The data suggest that representation of auditory frequency space exhibits some of the same biases as representation of visual physical space, and implications for theories of attention in displacement and for crossmodal and multisensory representation of space are discussed.

In the launching effect, a moving object (the launcher) contacts a stationary object (the target), and upon contact, the launcher stops and the target begins moving in the same direction and at the same or slower velocity as previous launcher motion (Michotte, 1946/1963). In the study reported here, participants viewed a modified launching effect display in which the launcher stopped before or at the moment of contact and the target remained stationary. Participants rated perceived causality, perceived force, and perceived resistance of the launcher on the target or the target on the launcher. For launchers and for targets, increases in the size of the spatial gap between the final location of the launcher and the location of the target decreased ratings of perceived causality and ratings of perceived force and increased ratings of perceived resistance. Perceived causality, perceived force, and perceived resistance exhibited gradients or fields extending from the launcher and from the target and were not dependent upon contact of the launcher and target. Causal asymmetries and force asymmetries reported in previous studies did not occur, and this suggests that such asymmetries might be limited to typical launching effect stimuli. Deviations from Newton's laws of motion are noted, and the existence of separate radii of action extending from the launcher and from the target is suggested.

Effects of cuing the onset (initial) location of a moving target on memory for the onset location of that target were examined. If a cue presented prior to target onset indicated the location where that target would appear, the onset repulsion effect (in which the judged initial location of the target was displaced in the direction opposite to target motion) was decreased, and the onset repulsion effect was smaller if the cue was valid than if the cue was invalid. If a cue presented during target motion or after the target vanished indicated the location where that target had appeared, the onset repulsion effect was eliminated. The data (1) suggest that positional uncertainty might contribute to the onset repulsion effect, (2) provide the first evidence of an effect of expectancy regarding target trajectory on the onset repulsion effect, and (3) are partially consistent with previous data involving effects of attention and spatial cuing on the Fröhlich effect and on representational momentum.

We determined the habitat usage and habitat connectivity of juvenile Chinook (Oncorhynchus tshawytscha) and coho (Oncorhynchus kisutch) salmon in continental shelf waters off Washington and Oregon, based on samples collected every June for 9 yr (1998–2006). Habitat usage and connectivity were evaluated using SeaWiFS satellite-derived chlorophyll a data and water depth. Logistic regression models were developed for both species, and habitats were first classified using a threshold value estimated from a receiver operating characteristic curve. A Bernoulli random process using catch probabilities from observed data, i.e. the frequency of occurrence of a fish divided by the number of times a station was surveyed, was applied to reclassify stations. Zero-catch probabilities of yearling Chinook and yearling coho salmon decreased with increases in chlorophyll a concentration, and with decreases in water depth. From 1998 to 2006, ∼ 47% of stations surveyed were classified as unfavorable habitat for yearling Chinook salmon and ∼ 53% for yearling coho salmon. Potentially favorable habitat varied among years and ranged from 9 856 to 15 120 km2 (Chinook) and from 14 800 to 16 736 km2 (coho). For both species, the smallest habitat area occurred in 1998, an El Nino year. Favorable habitats for yearling Chinook salmon were more isolated in 1998 and 2005 than in other years. Both species had larger and more continuous favorable habitat areas along the Washington coast than along the Oregon coast. The favorable habitats were also larger and more continuous nearshore than offshore for both species. Further investigations on large-scale transport, mesoscale physical features, and prey and predator availability in the study area are necessary to explain the spatial arrangement of juvenile salmon habitats in continental shelf waters.

Effects of the contrast of target luminance and background luminance, and of the absolute level of target luminance, on representational momentum for the remembered final location of a previously viewed moving target were examined. Targets were high in contrast or luminance, decreasing in contrast or luminance, increasing in contrast or luminance, or low in contrast or luminance; the background was black or white. Representational momentum for target location was larger if targets were high or increasing in contrast or luminance and smaller if targets were low or decreasing in contrast or luminance. Representational momentum for target location was larger if targets were presented on a white background than on a black background. Implications for theories of localization and for theories of representational momentum are discussed.

Microdamage naturally occurs in bone tissue as a result of cyclic loading placed on the body from normal daily activities. While it is usually repaired through the bone turnover process, accumulation of microdamage may result in reduced bone quality and increased fracture risk. It is unclear whether certain areas of bone are more susceptible to microdamage than others due to compositional differences. This study examines whether areas of microdamaged bone are chemically different than undamaged areas of bone. Bone samples (L3 vertebrae) were harvested from 15 dogs. Samples were stained with basic fuchsin, embedded in poly-methylmethacrylate, and cut into 5-microm-thick sections. Fuchsin staining was used to identify regions of microdamage, and synchrotron infrared microspectroscopic imaging was used to determine the local bone composition. Results showed that microdamaged areas of bone were chemically different than the surrounding undamaged areas. Specifically, the mineral stoichiometry was altered in microdamaged bone, where the carbonate/protein ratio and carbonate/phosphate ratio were significantly lower in areas of microdamage, and the acid phosphate content was higher. No differences were observed in tissue mineralization (phosphate/protein ratio) or crystallinity between the microdamaged and undamaged bone, indicating that the microdamaged regions of bone were not over-mineralized. The collagen cross-linking structure was also significantly different in microdamaged areas of bone, consistent with ruptured cross-links and reduced fracture resistance. All differences in composition had well-defined boundaries in the microcrack region, strongly suggesting that they occurred after microcrack formation. Even so, because microdamage results in an altered bone composition, an accumulation of microdamage might result in a long-term reduction in bone quality.

In Michotte's (1946/1963) launching effect paradigm, a moving launcher contacts a stationary target, and then the launcher becomes stationary and the target begins to move. In the experiments reported here, observers were presented with modifications of a launching effect display, and displacement in memory for targets was measured. Faster launcher velocities resulted in larger displacements for moving targets, and the effect of launcher velocity was larger with faster target velocities. Launcher velocity did not influence displacement of targets that remained stationary after contact. Increases in the distance travelled by moving targets after contact from the launcher resulted in smaller displacements. Displacement appeared to result from an expectation that impetus would be imparted from the launcher rather than from contact between the launcher and the target. Displacement patterns were consistent with naive impetus theory and with the hypothesis that observers believed impetus from the launcher was i...

In A. Michotte's (1946/1963) launching effect, a moving launcher contacts a stationary target, and then the launcher becomes stationary and the target begins to move. In this experiment, observers viewed modifications of a launching effect display, and displacement in memory for the location of targets was measured. Forward displacement of targets in launching effect displays was decreased relative to that of targets (a) that were presented in isolation and either moved at a constant fast or slow velocity or decelerated or (b) that moved in a direction orthogonal to previous motion of the launcher. Possible explanations involving a deceleration of motion or landmark attraction effects were ruled out. Displacement patterns were consistent with naive impetus theory and the hypothesis that observers believed impetus from the launcher was imparted to the target and then dissipated.

The effect of a large stationary landmark on memory for the location of a smaller moving target was examined. Forward displacement of the target was larger when the target moved toward the landmark than when it moved away from the landmark. Target size and direction of motion also influenced displacement. When the target passed close by the landmark, forward displacement of the target was larger before the target passed by the cardinal axis of the landmark than after the target passed by the cardinal axis of the landmark. Memory for a target that passed by a landmark was also displaced toward the target along the axis orthogonal to motion. Control experiments ruled out biases toward the centre of the screen as causing the differences in displacement. The data support the hypotheses that representational momentum may combine with landmark attraction effects to influence the displacement of a target along the axis of motion. Spatial memory exhibits a number of consistent biases. One type of bias distorts memory in ways consistent with the operation of environmentally invariant physical principles. For example, memory for the final position of a moving target that vanishes without warning is often distorted forward in the direction of anticipated future motion, and this bias has been referred to as representational momentum (e.g., Freyd & Finke, 1984; Hubbard, 1995b). A second type of bias distorts memory by decreasing the remembered distance between a target and a landmark (e.g., McNamara & Diwadkar, 1997; Sadalla, Burroughs, & Staplin, 1980; Tversky & Schiano, 1989), and this bias has been referred to as a landmark attraction effect (Bryant & Subbiah, 1994). These biases and distortions of memory result in a displacement of the remembered spatial position of a target; in other words, the remembered position of a previously perceived target stimulus is not the same as the actual position previously occupied by that target stimulus -- the remembered position is displaced from the actual position. Studies of representational momentum have suggested that memory for spatial location may be influenced by memory averaging (e.g., Freyd & Johnson, 1987). Hubbard (1995b) distinguished between two senses of memory averaging: A temporal sense in which memory for the final position of a target is influenced by the memory of prior positions of the target, and a spatial sense in which memory for the final position of a target is influenced by the memory of nontarget stimuli that were presented concurrently with the target. It may be possible that remembered prior positions of a target could serve as landmarks, and via temporal memory averaging account for displacements of remembered position toward the average of those prior positions. However, it is more obvious and perhaps more commonplace that nontarget stimuli or context presented concurrently with the target may serve as landmarks. The presence of such concurrent nontarget stimuli or context could provide the opportunity for spatial memory averaging. Indeed, the landmark attraction effect as it is currently conceived may be a special case of a more general spatial memory averaging: Both landmark attraction effects and spatial memory averaging predict that memory for the position of a target should be displaced in the direction of a landmark. Spatial memory averaging and landmark attraction effects are both consistent with a number of findings in the representational momentum literature. For example, if a rotating target is surrounded by a larger stationary square frame, forward displacement of the target is increased if the orientation of the frame is rotated slightly forward from the final orientation of the target, and forward displacement of the target is decreased if the orientation of the frame is rotated slightly backward from the final orientation of the target. Similarly, if the surrounding frame is in motion concurrently with the target, forward displacement of the target is increased if the frame is rotating in the same direction as the target, and forward displacement of the target is decreased if the frame is rotating in the direction opposite to the target (Hubbard, 1993). …

Six experiments examined displacement in memory for the location of the line in illusory line motion (ILM; appearance or disappearance of a stationary cue is followed by appearance of a stationary line that is presented all at once, but the stationary line is perceived to “unfold” or “be drawn” from the end closest to the cue to the end most distant from the cue). If ILM was induced by having a single cue appear, then memory for the location of the line was displaced toward the cue, and displacement was larger if the line was closer to the cue. If ILM was induced by having one of two previously visible cues vanish, then memory for the location of the line was displaced away from the cue that vanished. In general, the magnitude of displacement increased and then decreased as retention interval increased from 50 to 250 ms and from 250 to 450 ms, respectively. Displacement of the line (a) is consistent with a combination of a spatial averaging of the locations of the cue and the line with a relatively weaker dynamic in the direction of illusory motion, (b) might be implemented in a spreading activation network similar to networks previously suggested to implement displacement resulting from implied or apparent motion, and (c) provides constraints and challenges for theories of ILM.

The effects of line length and of spatial or temporal distance on illusory line motion (i.e., on the perception that a stationary line unfolds or expands away from a previously presented stationary cue) were examined in five experiments. Ratings of relative velocity decreased with increases in stimulus onset asynchrony between appearance of the cue and appearance of the line (from 50 to 450 ms), whereas the extremity of ratings of direction (i.e., strength of the ratings of illusory line motion) increased with increases in stimulus onset asynchrony (from 50 to either 250 or 450 ms). Ratings of relative velocity increased with increases in line length, whereas ratings of direction were not influenced by increases in line length. Ratings of relative velocity and direction were not influenced by increases in the distance of the near or the far end of the line from the cue. Implications of these data for attentional theories and apparent-motion theories of illusory line motion are discussed.

Summary Background Photodynamic therapy (PDT) is a promising treatment for superficial cancer. However, poor therapeutic results have been reported for melanoma, due to the high melanin content. Indocyanine green (ICG) has near infrared absorption (700–800 nm) and melanins do not absorb strongly in this area. This study explores the efficiency of ICG as a PDT agent for human melanoma, and its mechanistic role in the cell death pathway. Methods Human skin melanoma cells (Sk-Mel-28) were incubated with ICG and exposed to a low power Ti:Sapphire laser. Synchrotron-assisted Fourier transform infrared microspectroscopy and hierarchical cluster analysis were used to assess the cell damage and changes in lipid, protein, and nucleic acids. The cell death pathway was determined by analysis of cell viability and apoptosis and necrosis markers. Results In the cell death pathway, 1 O 2 generation evoked rapid multiple consequences that trigger apoptosis after laser exposure for only 15 min including the release of cytochrome c , the activation of total caspases, caspase-3, and caspase-9, the inhibition of NF-κB P65, and the enhancement of DNA fragmentation, and histone acetylation. Conclusion ICG/PDT can efficiently and rapidly induce apoptosis in human melanoma cells and it can be considered as a new therapeutic approach for topical treatment of melanoma.

The influence of feedback on representational momentum for the final location of a moving target was examined in 3 experiments. The presence of binary feedback (correct, error) during practise trials or during larger blocks of experimental trials did not reduce representational momentum, nor did the presence of more informative feedback specifying the direction of error (error-in front of, error-behind) during larger blocks of experimental trials reduce representational momentum. Effects on representational momentum of whether feedback was consistently provided were inconsistent. Even though feedback did not reduce representational momentum per se, feedback did influence the probability of a same response for different probe positions. Implications of the data for R. A. Finke and J. J. Freyd's (1985; J. J. Freyd, 1987) claim that representational momentum is impervious to error feedback, and possible roles of perceptual learning in representational momentum, are discussed.

Bone mineral density is the gold-standard for assessing bone quantity and diagnosing osteoporosis. Although bone mineral density measurements assess the quantity of bone, the quality of the tissue is an important predictor of fragility. Understanding the macro- and nanoscale properties of bone is critical to understanding bone fragility in osteoporosis. Osteoporosis is a disease that affects more than 75 million people worldwide. The gold standard for osteoporosis prognosis, bone mineral density, primarily measures the quantity of bone in the skeleton, overlooking more subtle aspects of bone's properties. Bone quality, a measure of bone's architecture, geometry and material properties, is evaluated via mechanical, structural and chemical testing. Although decreased BMD indicates tissue fragility at the clinical level, changes in the substructure of bone can help indicate how bone quality is altered in osteoporosis. Additionally, mechanical properties which can quantify fragility, or bone's inability to resist fracture, can be changed due to alterations in bone architecture and composition. Recent studies have focused on examination of bone on the nanoscale, suggesting the importance of understanding the interactions of the mineral crystals and collagen fibrils and how they can alter bone quality. It is therefore important to understand alterations in bone that occur at the macro-, micro- and nanoscopic levels to determine what parameters contribute to decreased bone quality in diseased tissue.

Full field hard X-ray microscopy has recently been developed utilizing synchrotron light, enabling absorption and phase contrast imaging with a spatial resolution of 50 -100 nm. This technique has allowed us to image bone tissue at the nanoscale level, viewing the substructure of mineralized collagen fibers. Thin sections of tissue (5 and 50 mum thick) from the L3 vertebrae of Beagles and mineralizing MC3T3-E1 mouse osteoblasts were imaged at beamline 01B1 at the National Synchrotron Radiation Research Center (Hsinchu, Taiwan). Collagen fiber orientation was observed in the lamellar structure of an osteon. Mineralizing osteoblasts were found to produce disordered mineralized nodules with varying density and structure.

Understanding how biomineralization occurs in the extracellular matrix (ECM) of bone cells is crucial to the development of a successfully engineered bone tissue scaffold, and to date there has not been a well-established method for the quantitative examination of bone mineralization in situ. We investigated the mechanical properties of MC3T3-E1 osteoblast-like cells and the crystalline properties of their biomineralized ECM in vitro using shear modulation force microscopy (SMFM), confocal laser scanning microscopy (CLSM), synchrotron X-ray diffraction (XRD), and Fourier-transform infrared spectroscopy (FTIR). The elastic modulus of the mineralizing cells increased at time points corresponding to mineral production, whereas that of the non-mineralizing cells did not vary significantly over time. CLSM showed a restructuring of the F-actin fiber network of mineralizing cells with time, which indicates remodeling activities in the cytoskeleton and was not seen in the non-mineralizing cells. Both XRD and FTIR showed that the mineralizing subclone produced hydroxyapatite in situ and that the non-mineralizing subclone was in fact weakly biomineralizing.

In A. Michotte's (1946/1963) launching effect, a moving launcher contacts a stationary target, and then the launcher becomes stationary and the target begins to move. In this experiment, observers viewed modifications of a launching effect display, and displacement in memory for the location of targets was measured. Forward displacement of targets in launching effect displays was decreased relative to that of targets (a) that were presented in isolation and either moved at a constant fast or slow velocity or decelerated or (b) that moved in a direction orthogonal to previous motion of the launcher. Possible explanations involving a deceleration of motion or landmark attraction effects were ruled out. Displacement patterns were consistent with naive impetus theory and the hypothesis that observers believed impetus from the launcher was imparted to the target and then dissipated.

The effect of a large stationary landmark on memory for the location of a stationary target was examined. Memory for a stationary target was displaced toward the landmark, and targets that were larger, further from, or above the landmark exhibited greater magnitudes of displacement. Displacement was generally larger when the landmark vanished prior to judgment than when the landmark was visible during judgment. Memory for stationary targets offset from the major vertical or horizontal cardinal axis of the landmark was also displaced toward that cardinal axis. The data support the hypotheses that spatial memory averaging of the locations of a target and landmark occurs, and that this averaging may be combined with representational gravity in determining the remembered position of a stationary target.

Previous research supports the activational role of central cholinergic mechanisms in rodent female sexual behavior. This experiment examined if similar central cholinergic mechanisms facilitate female rhesus monkey ( Macaca mulatta ) sexual behavior. Eight ovariectomized female rhesus monkeys received daily estradiol benzoate priming (5 μg/kg, SC). After 13–16 days of estrogen priming, animals were injected intravenously with either the cholinergic antagonist, scopolamine (0.70 mg/kg), or saline vehicle (1 ml/kg). Results indicate that the female proceptive behaviors of noncontact presentations significantly decreased 15–45 min after scopolamine injection. Scopolamine inhibition was sustained up to 75 min only after 15 days of estrogen priming. Scopolamine did not significantly reduce other female sexual behaviors. Additionally, significant decreases in the number of mounts and intromissions, but not hip touches, were displayed by males exposed to scopolamine-treated females. This research suggests the possibility of a central cholinergic mechanism regulating female sexual behavior in rhesus monkeys. However, the general nature and duration of the cholinergic regulation of primate female sexual behavior differs substantially when compared to rodent behavior.

Analysis of DDT contamination in selected finfish and shellfish species from estuarine and coastal marine waters of New Jersey (USA) reveals consistently highest organochlorine pesticide levels in samples from the north and northeast regions of the state. The mean concentrations of DDT and its metabolites, DDE and DDD, in bluefish, striped bass, weakfish, and blue crabs collected at 27 stations throughout the state between 1988 and 1991 ranged from25 to300 microg/kg wet weight (wet wt). Gas chromatographic analysis of 175 tissue samples from these four species showed that the highest levels of DDTs (DDT plus DDE and DDD), exceeding 300 microg/kg wet wt, occurred in blue crabs (hepatopancreas) from the Hudson-Newark-Raritan Bay complex in the northeast region. Lower mean concentrations of DDTs (200 microg/kg wet wt) were recorded in tissue samples of these species from all other regions of the state. The lowest levels of DDT contamination (mean110 microg/kg wet wt) were found in samples from the south coast region. The greatest impact of DDT contamination is nearby metropolitan areas of the state, although the total concentrations of DDT in tissue samples from these areas are far less than the U.S. Food and Drug Administration action level of 5,000 microg/kg wet wt for this contaminant.

Synchrotron x-ray fluorescence (XRF) microprobe is a valuable analysis tool for imaging trace element composition in situ at a resolution of a few microns. Frequently, epifluorescence microscopy is beneficial for identifying the region of interest. To date, combining epifluorescence microscopy with x-ray microprobe has involved analyses with two different microscopes. We report the development of an epifluorescence module that is integrated into a synchrotron XRF microprobe beamline, such that visible fluorescence from a sample can be viewed while collecting x-ray microprobe images simultaneously. This unique combination has been used to identify metal accumulation in Alzheimer’s disease plaques and the mineral distribution in geological samples. The flexibility of this accessory permits its use on almost any synchrotron x-ray fluorescence microprobe beamline and applications in many fields of science can benefit from this technology.

The product engineering design study of Cartridge, 37mm, spotting, XM415, which is a sub-caliber component of the XM29 Weapons System is reported. Experience gained at Lake City Arsenal in the production engineering and initial manufacturing phase of Cartridge, 20mm, spotting, XM101, was fully utilized and applied. Twenty-one completely dimensioned and annotated component drawings were generated, but no actual metal parts were made or tested. The modified cartridge case is similar in basic design to the 20mm XM154. Two case plugs of different internal volume fit the case body to provide the two ranges required of the spotter round. The case wall thickness is the minimum which will safely withstand anticipated excess chamber pressure requirements without additional heat-treatment. The projectile was simplified and improved by changing to a conventional one-piece body with a male threaded fuze intruding into the mouth. Several internal changes were made for simplification of manufacture, assembly, or both, and several components were eliminated thereby. The counterweight was changed from lead to D-38 which was a major factor in the increase of the payload by 23% over the Picatinny Arsenal projectile.

The sound spectrograph shows variations in signal intensity by varying shades of gray to black, which, because of the nature of the recording medium, are not susceptible to quantitative interpretation. Several methods are described in this paper for recording amplitude variations in measurable steps. These methods include contours, dot spacing, distinctive shadings, and variable area patterns.