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Background. The root-mean-square charge radii are the important characteristics of atomic nuclei which might be measured experimentally. In this research, we study the experimental data on the root-mean-square charge radii of the spherical nuclei available in the literature. The purpose of this analysis is to establish what is the manifestation of the neutron shells in the considered observable and to find regularities in the behavior of the charge radii when a shell is crossed. Materials and methods. The present analysis is performed by means of calculation of the relative charge radius for a given element x = x (N, Nsh , Z ). This value is equal to the charge radius of an isotope with neutron number N over the charge radius of the isotope t with the closed neutron shell N = Nsh . Results. As the result, we have found manifestation of the shells Nsh = 8, 28, 50 and 82. It turns out that the well-known shells with the neutron numbers 20 and 126 do not show up. Conclusions. It is shown that the values of relative charge radius form groups corresponding to different values of Nsh . On the basis of the revealed regularity, the charge radius is predicted for isotope 30 S which is absent among the experimental data.

Efficacy and safety of long acting 29 agonist formoterol (foradil aerolizer) was investigated in comparative study. 30 pediatric patients (6–16 years old) with bronchial asthma were treated with formoterol. 100 ?g of salbutamol by metered9dose inhaler was administered to control group of children (n = 30). The bronchodilating effect of formoterol was comparable to that of short acting 29 agonist salbutamol. Maximal bronchodilating action was registered in 2–4 hours after inhalation and lasted out more then 12 hours. For moterol aerolizer can be easily applicated and allows to carry out doctor's recommendations and to increase the effectiveness of treatment. Formoterol aerolizer allows making greatly less mistakes in inhalation technique then salbutamol in metered dose inhaler. Authors made a conclusion that for moterol can be used as a rescue treatment in children with bronchial asthma upwards 5 years old treated with appropriate basis regimens.Key words: children, bronchial asthma, formoterol, aerolizer.

Efficacy and safety of long acting 29 agonist formoterol (foradil aerolizer) was investigated in comparative study. 30 pediatric patients (6–16 years old) with bronchial asthma were treated with formoterol. 100 ?g of salbutamol by metered9dose inhaler was administered to control group of children (n = 30). The bronchodilating effect of formoterol was comparable to that of short acting 29 agonist salbutamol. Maximal bronchodilating action was registered in 2–4 hours after inhalation and lasted out more then 12 hours. For moterol aerolizer can be easily applicated and allows to carry out doctor's recommendations and to increase the effectiveness of treatment. Formoterol aerolizer allows making greatly less mistakes in inhalation technique then salbutamol in metered dose inhaler. Authors made a conclusion that for moterol can be used as a rescue treatment in children with bronchial asthma upwards 5 years old treated with appropriate basis regimens.Key words: children, bronchial asthma, formoterol, aerolizer.