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1. Antiviral cellular therapy for enhancing T-cell reconstitution before or after hematopoietic stem cell transplantation (ACES): a two-arm, open label phase II interventional trial of pediatric patients with risk factor assessment

Author

Keller, Michael D., Hanley, Patrick J., Chi, Yueh-Yun, Aguayo-Hiraldo, Paibel, Dvorak, Christopher C., Verneris, Michael R., Kohn, Donald B., Pai, Sung-Yun, Dávila Saldaña, Blachy J., Hanisch, Benjamin, Quigg, Troy C., Adams, Roberta H., Dahlberg, Ann, Chandrakasan, Shanmuganathan, Hasan, Hasibul, Malvar, Jemily, Jensen-Wachspress, Mariah A., Lazarski, Christopher A., Sani, Gelina, Idso, John M., Lang, Haili, Chansky, Pamela, McCann, Chase D., Tanna, Jay, Abraham, Allistair A., Webb, Jennifer L., Shibli, Abeer, Keating, Amy K., Satwani, Prakash, Muranski, Pawel, Hall, Erin, Eckrich, Michael J., Shereck, Evan, Miller, Holly, Mamcarz, Ewelina, Agarwal, Rajni, De Oliveira, Satiro N., Vander Lugt, Mark T., Ebens, Christen L., Aquino, Victor M., Bednarski, Jeffrey J., Chu, Julia, Parikh, Suhag, Whangbo, Jennifer, Lionakis, Michail, Zambidis, Elias T., Gourdine, Elizabeth, Bollard, Catherine M., and Pulsipher, Michael A.

Published
2024
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2. Association of busulfan exposure and outcomes after HCT for patients with an inborn error of immunity

Author

Bognàr, Tim, Garcia-Rosa, Moises, Lalmohamed, Arief, Güngör, Tayfun, Hauri-Hohl, Mathias, Prockop, Susan, Oram, Layne, Pai, Sung-Yun, Brooks, Jordan, Savic, Rada M., Dvorak, Christopher C., Long-Boyle, Janel R., Krajinovic, Maja, Bittencourt, Henrique, Teyssier, Anne-Charlotte, Théorêt, Yves, Martinez, Cary, Egberts, Toine C. G., Morales, Erin, Slatter, Mary, Cuvelier, Geoffrey D. E., Chiesa, Robert, Wynn, Robert F., Coussons, Mary, Cicalese, Maria P., Ansari, Marc, Long, Susan E., Ebens, Christen L., Lust, Hannah, Chaudhury, Sonali, Nath, Christa E., Shaw, Peter J., Keogh, Steven J., van der Stoep, M. Y. Eileen C., Bredius, Robbert, Lindemans, Caroline A., Boelens, Jaap-Jan, and Bartelink, Imke H.

Published
2024
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5. Posttransplantation late complications increase over time for patients with SCID: A Primary Immune Deficiency Treatment Consortium (PIDTC) landmark study

Author

Eissa, Hesham, Thakar, Monica S., Shah, Ami J., Logan, Brent R., Griffith, Linda M., Dong, Huaying, Parrott, Roberta E., O’Reilly, Richard J., Dara, Jasmeen, Kapoor, Neena, Forbes Satter, Lisa, Chandra, Sharat, Kapadia, Malika, Chandrakasan, Shanmuganathan, Knutsen, Alan, Jyonouchi, Soma C., Molinari, Lyndsay, Rayes, Ahmad, Ebens, Christen L., Teira, Pierre, Dávila Saldaña, Blachy J., Burroughs, Lauri M., Chaudhury, Sonali, Chellapandian, Deepak, Gillio, Alfred P., Goldman, Fredrick, Malech, Harry L., DeSantes, Kenneth, Cuvelier, Geoff D.E., Rozmus, Jacob, Quinones, Ralph, Yu, Lolie C., Broglie, Larisa, Aquino, Victor, Shereck, Evan, Moore, Theodore B., Vander Lugt, Mark T., Mousallem, Talal I., Oved, Joeseph H., Dorsey, Morna, Abdel-Azim, Hisham, Martinez, Caridad, Bleesing, Jacob H., Prockop, Susan, Kohn, Donald B., Bednarski, Jeffrey J., Leiding, Jennifer, Marsh, Rebecca A., Torgerson, Troy, Notarangelo, Luigi D., Pai, Sung-Yun, Pulsipher, Michael A., Puck, Jennifer M., Dvorak, Christopher C., Haddad, Elie, Buckley, Rebecca H., Cowan, Morton J., and Heimall, Jennifer

Published
2024
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6. Impact of pre-transplant induction and consolidation cycles on AML allogeneic transplant outcomes: a CIBMTR analysis in 3113 AML patients

Author

Boyiadzis, Michael, Zhang, Mei-Jie, Chen, Karen, Abdel-Azim, Hisham, Abid, Muhammad Bilal, Aljurf, Mahmoud, Bacher, Ulrike, Badar, Talha, Badawy, Sherif M., Battiwalla, Minoo, Bejanyan, Nelli, Bhatt, Vijaya Raj, Brown, Valerie I., Castillo, Paul, Cerny, Jan, Copelan, Edward A., Craddock, Charles, Dholaria, Bhagirathbhai, Perez, Miguel Angel Diaz, Ebens, Christen L., Gale, Robert Peter, Ganguly, Siddhartha, Gowda, Lohith, Grunwald, Michael R., Hashmi, Shahrukh, Hildebrandt, Gerhard C., Iqbal, Madiha, Jamy, Omer, Kharfan-Dabaja, Mohamed A., Khera, Nandita, Lazarus, Hillard M., Lin, Richard, Modi, Dipenkumar, Nathan, Sunita, Nishihori, Taiga, Patel, Sagar S., Pawarode, Attaphol, Saber, Wael, Sharma, Akshay, Solh, Melhem, Wagner, John L., Wang, Trent, Williams, Kirsten M., Winestone, Lena E., Wirk, Baldeep, Zeidan, Amer, Hourigan, Christopher S., Litzow, Mark, Kebriaei, Partow, de Lima, Marcos, Page, Kristin, and Weisdorf, Daniel J.

Published
2023
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7. Genotype, oxidase status, and preceding infection or autoinflammation do not affect allogeneic HCT outcomes for CGD

Author

Leiding, Jennifer W., Arnold, Danielle E., Parikh, Suhag, Logan, Brent, Marsh, Rebecca A., Griffith, Linda M., Wu, Ruizhe, Kidd, Sharon, Mallhi, Kanwaldeep, Chellapandian, Deepak, Si Lim, Stephanie J., Grunebaum, Eyal, Falcone, E. Liana, Murguia-Favela, Luis, Grossman, Debbi, Prasad, Vinod K., Heimall, Jennifer R., Touzot, Fabien, Burroughs, Lauri M., Bleesing, Jack, Kapoor, Neena, Dara, Jasmeen, Williams, Olatundun, Kapadia, Malika, Oshrine, Benjamin R., Bednarski, Jeffrey J., Rayes, Ahmad, Chong, Hey, Cuvelier, Geoffrey D. E., Forbes Satter, Lisa R., Martinez, Caridad, Vander Lugt, Mark T., Yu, Lolie C., Chandrakasan, Shanmuganathan, Joshi, Avni, Prockop, Susan E., Dávila Saldaña, Blachy J., Aquino, Victor, Broglie, Larisa A., Ebens, Christen L., Madden, Lisa M., DeSantes, Kenneth, Milner, Jordan, Rangarajan, Hemalatha G., Shah, Ami J., Gillio, Alfred P., Knutsen, Alan P., Miller, Holly K., Moore, Theodore B., Graham, Pamela, Bauchat, Andrea, Bunin, Nancy J., Teira, Pierre, Petrovic, Aleksandra, Chandra, Sharat, Abdel-Azim, Hisham, Dorsey, Morna J., Birbrayer, Olga, Cowan, Morton J., Dvorak, Christopher C., Haddad, Elie, Kohn, Donald B., Notarangelo, Luigi D., Pai, Sung-Yun, Puck, Jennifer M., Pulsipher, Michael A., Torgerson, Troy R., Malech, Harry L., and Kang, Elizabeth M.

Published
2023
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8. Measuring the effect of newborn screening on survival after haematopoietic cell transplantation for severe combined immunodeficiency: a 36-year longitudinal study from the Primary Immune Deficiency Treatment Consortium

Author

Thakar, Monica S, Logan, Brent R, Puck, Jennifer M, Dunn, Elizabeth A, Buckley, Rebecca H, Cowan, Morton J, O'Reilly, Richard J, Kapoor, Neena, Satter, Lisa Forbes, Pai, Sung-Yun, Heimall, Jennifer, Chandra, Sharat, Ebens, Christen L, Chellapandian, Deepak, Williams, Olatundun, Burroughs, Lauri M, Saldana, Blachy Davila, Rayes, Ahmad, Madden, Lisa M, Chandrakasan, Shanmuganathan, Bednarski, Jeffrey J, II, DeSantes, Kenneth B, Cuvelier, Geoffrey D E, Teira, Pierre, Gillio, Alfred P, Eissa, Hesham, Knutsen, Alan P, Goldman, Frederick D, Aquino, Victor M, Shereck, Evan B, Moore, Theodore B, Caywood, Emi H, Lugt, Mark T Vander, Rozmus, Jacob, Broglie, Larisa, Yu, Lolie C, Shah, Ami J, Andolina, Jeffrey R, Liu, Xuerong, Parrott, Roberta E, Dara, Jasmeen, Prockop, Susan, Martinez, Caridad A, Kapadia, Malika, Jyonouchi, Soma C, Sullivan, Kathleen E, Bleesing, Jack J, Chaudhury, Sonali, Petrovic, Aleksandra, Keller, Michael D, Quigg, Troy C, Parikh, Suhag, Shenoy, Shalini, Seroogy, Christine, Rubin, Tamar, Decaluwe, Hélène, Routes, John M, Torgerson, Troy R, Leiding, Jennifer W, Pulsipher, Michael A, Kohn, Donald B, Griffith, Linda M, Haddad, Elie, Dvorak, Christopher C, and Notarangelo, Luigi D

Published
2023
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9. The diagnosis of severe combined immunodeficiency: Implementation of the PIDTC 2022 Definitions

Author

Dvorak, Christopher C., Haddad, Elie, Heimall, Jennifer, Dunn, Elizabeth, Cowan, Morton J., Pai, Sung-Yun, Kapoor, Neena, Satter, Lisa Forbes, Buckley, Rebecca H., O’Reilly, Richard J., Chandra, Sharat, Bednarski, Jeffrey J., Williams, Olatundun, Rayes, Ahmad, Moore, Theodore B., Ebens, Christen L., Davila Saldana, Blachy J., Petrovic, Aleksandra, Chellapandian, Deepak, Cuvelier, Geoffrey D.E., Vander Lugt, Mark T., Caywood, Emi H., Chandrakasan, Shanmuganathan, Eissa, Hesham, Goldman, Frederick D., Shereck, Evan, Aquino, Victor M., Desantes, Kenneth B., Madden, Lisa M., Miller, Holly K., Yu, Lolie, Broglie, Larisa, Gillio, Alfred, Shah, Ami J., Knutsen, Alan P., Andolina, Jeffrey P., Joshi, Avni Y., Szabolcs, Paul, Kapadia, Malika, Martinez, Caridad A., Parrot, Roberta E., Sullivan, Kathleen E., Prockop, Susan E., Abraham, Roshini S., Thakar, Monica S., Leiding, Jennifer W., Kohn, Donald B., Pulsipher, Michael A., Griffith, Linda M., Notarangelo, Luigi D., and Puck, Jennifer M.

Published
2023
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10. Allogeneic Hematopoietic Cell Transplant For Bone Marrow Failure or Myelodysplastic Syndrome in Dyskeratosis Congenita/Telomere Biology Disorders: Single-Center, Single-Arm, Open-Label Trial of Reduced-Intensity Conditioning Without Radiation

Author

Dimitrov, Marketa, Merkle, Svatava, Cao, Qing, Tryon, Rebecca K., Vercellotti, Gregory M., Holtan, Shernan G., Kao, Roy L., Srikanthan, Meera, Terezakis, Stephanie A., Tolar, Jakub, and Ebens, Christen L.

Published
2024
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12. Outcomes following treatment for ADA-deficient severe combined immunodeficiency: a report from the PIDTC

Author

Cuvelier, Geoffrey D.E., Logan, Brent R., Prockop, Susan E., Buckley, Rebecca H., Kuo, Caroline Y., Griffith, Linda M., Liu, Xuerong, Yip, Alison, Hershfield, Michael S., Ayoub, Paul G., Moore, Theodore B., Dorsey, Morna J., O'Reilly, Richard J., Kapoor, Neena, Pai, Sung-Yun, Kapadia, Malika, Ebens, Christen L., Forbes Satter, Lisa R., Burroughs, Lauri M., Petrovic, Aleksandra, Chellapandian, Deepak, Heimall, Jennifer, Shyr, David C., Rayes, Ahmad, Bednarski, Jeffrey J., Chandra, Sharat, Chandrakasan, Shanmuganathan, Gillio, Alfred P., Madden, Lisa, Quigg, Troy C., Caywood, Emi H., Dávila Saldaña, Blachy J., DeSantes, Kenneth, Eissa, Hesham, Goldman, Frederick D., Rozmus, Jacob, Shah, Ami J., Vander Lugt, Mark T., Thakar, Monica S., Parrott, Roberta E., Martinez, Caridad, Leiding, Jennifer W., Torgerson, Troy R., Pulsipher, Michael A., Notarangelo, Luigi D., Cowan, Morton J., Dvorak, Christopher C., Haddad, Elie, Puck, Jennifer M., and Kohn, Donald B.

Published
2022
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13. Correction to: Impact of pre-transplant induction and consolidation cycles on AML allogeneic transplant outcomes: a CIBMTR analysis in 3113AML patients

Author

Boyiadzis, Michael, Zhang, Mei-Jie, Chen, Karen, Abdel-Azim, Hisham, Abid, Muhammad Bilal, Aljurf, Mahmoud, Bacher, Ulrike, Badar, Talha, Badawy, Sherif M., Battiwalla, Minoo, Bejanyan, Nelli, Bhatt, Vijaya Raj, Brown, Valerie I., Castillo, Paul, Cerny, Jan, Copelan, Edward A., Craddock, Charles, Dholaria, Bhagirathbhai, Perez, Miguel Angel Diaz, Ebens, Christen L., Gale, Robert Peter, Ganguly, Siddhartha, Gowda, Lohith, Grunwald, Michael R., Hashmi, Shahrukh, Hildebrandt, Gerhard C., Iqbal, Madiha, Jamy, Omer, Kharfan-Dabaja, Mohamed A., Khera, Nandita, Lazarus, Hillard M., Lin, Richard, Modi, Dipenkumar, Nathan, Sunita, Nishihori, Taiga, Patel, Sagar S., Pawarode, Attaphol, Saber, Wael, Sharma, Akshay, Solh, Melhem, Wagner, John L., Wang, Trent, Williams, Kirsten M., Winestone, Lena E., Wirk, Baldeep, Zeidan, Amer, Hourigan, Christopher S., Litzow, Mark, Kebriaei, Partow, de Lima, Marcos, Page, Kristin, and Weisdorf, Daniel J.

Published
2023
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15. Liver disease and transplantation in telomere biology disorders: An international multicenter cohort.

Author

Wang, YunZu Michele, Kaj-Carbaidwala, Batul, Lane, Adam, Agarwal, Suneet, Beier, Fabian, Bertuch, Alison, Borovsky, Kristin A., Brennan, Steven K., Calado, Rodrigo T., Catto, Luiz Fernando B., Dufour, Carlo, Ebens, Christen L., Fioredda, Francesca, Giri, Neelam, Gloude, Nicholas, Goldman, Frederick, Hertel, Paula M., Himes, Ryan, Keel, Sioban B., and Koura, Divya T.

Published
2024
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16. Outcomes Following Matched Sibling Donor Transplant for Severe Combined Immunodeficiency: A Report from the Pidtc

Author

Rayes, Ahmad, primary, Logan, Brent, additional, Liu, Xuerong, additional, Dara, Jasmeen, additional, Buckley, Rebecca H., additional, Oved, Joseph H., additional, Kapoor, Neena, additional, Kapadia, Malika, additional, Chandra, Sharat, additional, Martinez, Caridad, additional, Bunin, Nancy J., additional, Chandrakasan, Shanmuganathan, additional, Burroughs, Lauri M., additional, Bednarski, Jeffrey J, additional, Haines, Hilary, additional, Cuvelier, Geoff D.E., additional, Eissa, Hesham, additional, Talano, Julie A, additional, Saldana, Blachy J, additional, Ebens, Christen L., additional, Chaudhury, Sonali, additional, Shereck, Evan, additional, Aquino, Victor, additional, Knutsen, Alan P., additional, Alexander, Jessie L, additional, Gillio, Alfred P., additional, Chellapandian, Deepak, additional, Shah, Ami J., additional, Miller, Holly K., additional, Lugt, Mark T. Vander, additional, DeSantes, Kenneth, additional, Dorsey, Morna, additional, Parrott, Roberta E, additional, O'Reilly, Richard J., additional, Aguayo-Hiraldo, Paibel, additional, Torgerson, Troy, additional, Leiding, Jennifer W., additional, Marsh, Rebecca A., additional, Griffith, Linda M., additional, Pulsipher, Mike A., additional, Kohn, Donald B., additional, Notarangelo, Luigi D., additional, Cowan, Morton J., additional, Puck, Jennifer, additional, Heimall, Jennifer R., additional, Haddad, Elie, additional, Pai, Sung-Yun, additional, and Dvorak, Christopher C., additional

Published
2024
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21. Posttransplantation late complications increase over time for patients with SCID: A Primary Immune Deficiency Treatment Consortium (PIDTC) landmark study

Author

Eissa, Hesham, primary, Thakar, Monica S., additional, Shah, Ami J., additional, Logan, Brent R., additional, Griffith, Linda M., additional, Dong, Huaying, additional, Parrott, Roberta E., additional, O’Reilly, Richard J., additional, Dara, Jasmeen, additional, Kapoor, Neena, additional, Forbes Satter, Lisa, additional, Chandra, Sharat, additional, Kapadia, Malika, additional, Chandrakasan, Shanmuganathan, additional, Knutsen, Alan, additional, Jyonouchi, Soma C., additional, Molinari, Lyndsay, additional, Rayes, Ahmad, additional, Ebens, Christen L., additional, Teira, Pierre, additional, Dávila Saldaña, Blachy J., additional, Burroughs, Lauri M., additional, Chaudhury, Sonali, additional, Chellapandian, Deepak, additional, Gillio, Alfred P., additional, Goldman, Fredrick, additional, Malech, Harry L., additional, DeSantes, Kenneth, additional, Cuvelier, Geoff D.E., additional, Rozmus, Jacob, additional, Quinones, Ralph, additional, Yu, Lolie C., additional, Broglie, Larisa, additional, Aquino, Victor, additional, Shereck, Evan, additional, Moore, Theodore B., additional, Vander Lugt, Mark T., additional, Mousallem, Talal I., additional, Oved, Joeseph H., additional, Dorsey, Morna, additional, Abdel-Azim, Hisham, additional, Martinez, Caridad, additional, Bleesing, Jacob H., additional, Prockop, Susan, additional, Kohn, Donald B., additional, Bednarski, Jeffrey J., additional, Leiding, Jennifer, additional, Marsh, Rebecca A., additional, Torgerson, Troy, additional, Notarangelo, Luigi D., additional, Pai, Sung-Yun, additional, Pulsipher, Michael A., additional, Puck, Jennifer M., additional, Dvorak, Christopher C., additional, Haddad, Elie, additional, Buckley, Rebecca H., additional, Cowan, Morton J., additional, and Heimall, Jennifer, additional

Published
2023
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27. Revisiting Pre-Transplant Testicular Radiation for Relapse Prophylaxis in Allogeneic Hematopoietic Cell Transplantation (HCT) for Acute Lymphoblastic Leukemia (ALL)

Author

Summers, Corinne, primary, Bhatt, Neel S., additional, Jenssen, Kari, additional, Hoover, Alex, additional, Ebens, Christen L., additional, Schaefer, Edo, additional, Cairo, Mitchell S., additional, Carpenter, Paul A., additional, Dahlberg, Ann, additional, Hadland, Brandon, additional, Bleakley, Marie, additional, and Thakar, Monica S., additional

Published
2023
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28. Event Free Survival in Severe Combined Immune Deficiency (SCID) Infants after Conditioned Umbilical Cord Blood Transplantation (UCBT) Benefits from Omitting Serotherapy

Author

Martinez, Caridad, primary, Logan, Brent, additional, Liu, Xuerong, additional, Dvorak, Christopher C., additional, Madden, Lisa, additional, Molinari, Lyndsay, additional, Cowan, Morton J., additional, Pai, Sung-Yun, additional, Haddad, Elie, additional, Puck, Jennifer, additional, Kohn, Donald B., additional, Griffith, Linda M., additional, Pulsipher, Michael, additional, Leiding, Jennifer W., additional, Notarangelo, Luigi D., additional, Torgerson, Troy, additional, Marsh, Rebecca A., additional, Cuvelier, Geoff D.E., additional, Prockop, Susan, additional, Buckley, Rebecca H., additional, Kuo, Caroline Y., additional, Yip, Alison, additional, Hershfield, Michael S., additional, Parrott, Roberta E, additional, Ebens, Christen L., additional, Moore, Theodore B., additional, O’Reilly, Richard J., additional, Kapadia, Malika, additional, Kapoor, Neena, additional, Satter, Lisa Forbes, additional, Burroughs, Lauri M., additional, Petrovic, Aleksandra, additional, Thakar, Monica S., additional, Chellapandian, Deepak, additional, Heimall, Jennifer R., additional, Shyr, David C., additional, Bednarski, Jeffrey J, additional, Rayes, Ahmad, additional, Chandrakasan, Shanmuganathan, additional, Quigg, Troy C., additional, Davila, Blachy J, additional, DeSantes, Kenneth, additional, Eissa, Hesham, additional, Goldman, Frederick, additional, Rozmus, Jacob, additional, Shah, Ami J, additional, Lugt, Mark Vander, additional, Keller, Michael D., additional, Sullivan, Kathleen E., additional, Jyonouchi, Soma, additional, Seroogy, Christine, additional, Decaluwe, Helene, additional, Teira, Pierre, additional, Knutsen, Alan P., additional, Kletzel, Morris, additional, Aquino, Victor, additional, Davis, Jeffrey H, additional, and Szabolcs, Paul, additional

Published
2023
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29. Donor Derived Leukemia in a Recipient of Allogeneic Hematopoietic Cell Transplantation for Recessive Dystrophic Epidermolysis Bullosa

Author

Major-Monfried, Hannah, primary, Shukla, Neerav, additional, Scaradavou, Andromachi, additional, Cancio, Maria I., additional, Harris, Andrew C., additional, Boelens, Jaap-Jan, additional, Curran, Kevin J., additional, Oved, Joseph H., additional, Tolar, Jakub, additional, Kernan, Nancy A., additional, Ebens, Christen L., additional, and Spitzer, Barbara, additional

Published
2023
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30. Allogeneic Hematopoietic Stem Cell Transplantation (HCT) Using Reduced Intensity Conditioning with Cyclophosphamide/Fludarabine/Total Body Irradiation (TBI) with Tacrolimus, MMF, and Conditional Anti Thymocyte Globulin (ATG) for the Treatment of Hematological Malignancies

Author

Firoozmand, Amin, primary, O’Leary, Daniel, additional, Cao, Qing, additional, Gupta, Ashish O., additional, Ebens, Christen L., additional, Maakaron, Joseph E., additional, Betts, Brian C., additional, Lund, Troy, additional, Bachanova, Veronika, additional, MacMillan, Margaret L., additional, Miller, Jeffrey S., additional, Orchard, Paul J., additional, Wagner, John E., additional, Vercellotti, Gregory M, additional, Weisdorf, Daniel J., additional, Dusenbery, Kathryn, additional, Terezakis, Stephanie, additional, Holtan, Shernan Grace, additional, Jurdi, Najla El, additional, and Juckett, Mark, additional

Published
2023
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31. Revisiting the Role of Post-Transplant Central Nervous System Prophylaxis in Allogeneic Hematopoietic Cell Transplantation for Acute Lymphoblastic Leukemia

Author

Bhatt, Neel S., primary, Summers, Corinne, additional, Jenssen, Kari, additional, Hoover, Alex, additional, Ebens, Christen L., additional, Schaefer, Edo, additional, Cairo, Mitchell S., additional, Carpenter, Paul A., additional, Dahlberg, Ann, additional, Hadland, Brandon, additional, Bleakley, Marie, additional, and Thakar, Monica S., additional

Published
2023
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32. Phase II Study of Myeloablative 8/8- or 7/8-Matched Allotransplantation with Post-Transplant Cyclophosphamide, Tacrolimus, and Mycophenolate Mofetil: Marked Reduction in Gvhd Risk without Increase Relapse Risk Compared to Historical Cyclosporine/ Methotrexate

Author

Holtan, Shernan Grace, primary, Hoover, Alex, additional, O’Leary, Daniel, additional, Cao, Qing, additional, Gupta, Ashish, additional, Ebens, Christen L., additional, Maakaron, Joseph E., additional, Betts, Brian C., additional, Juckett, Mark, additional, Lund, Dr. Troy C., additional, Bachanova, Veronika, additional, MacMillan, Margaret L., additional, Miller, Jeffrey S., additional, Orchard, Paul J., additional, Wagner, John E., additional, Vercellotti, Gregory M, additional, Weisdorf, Daniel J., additional, Dusenbery, Kathryn, additional, Terezakis, Stephanie, additional, and Jurdi, Najla El, additional

Published
2023
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33. Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands

Author

Chung, Jooho, Ebens, Christen L., Perkey, Eric, Radojcic, Vedran, Koch, Ute, Scarpellino, Leonardo, Tong, Alexander, Allen, Frederick, Wood, Sherri, Feng, Jiane, Friedman, Ann, Granadier, David, Tran, Ivy T., Chai, Qian, Onder, Lucas, Yan, Minhong, Reddy, Pavan, Blazar, Bruce R., Huang, Alex Y., Brennan, Todd V., Bishop, D. Keith, Ludewig, Burkhard, Siebel, Christian W., Radtke, Freddy, Luther, Sanjiv A., and Maillard, Ivan

Subjects
Graft vs. host disease -- Genetic aspects -- Development and progression -- Care and treatment, Cellular signal transduction -- Genetic aspects -- Health aspects, Signaling peptides and proteins -- Health aspects, Health care industry
Abstract

Alloimmune T cell responses induce graft-versus-host disease (GVHD), a serious complication of allogeneic bone marrow transplantation (allo-BMT). Although Notch signaling mediated by Delta-like 1/4 (DLL1/4) Notch ligands has emerged as a major regulator of GVHD pathogenesis, little is known about the timing of essential Notch signals and the cellular source of Notch ligands after allo-BMT. Here, we have shown that critical DLL1/4-mediated Notch signals are delivered to donor T cells during a short 48-hour window after transplantation in a mouse allo-BMT model. Stromal, but not hematopoietic, cells were the essential source of Notch ligands during in vivo priming of alloreactive T cells. GVHD could be prevented by selective inactivation of Dll1 and Dll4 in subsets of fibroblastic stromal cells that were derived from chemokine Ccl19-expressing host cells, including fibroblastic reticular cells and follicular dendritic cells. However, neither T cell recruitment into secondary lymphoid organs nor initial T cell activation was affected by Dll1/4 loss. Thus, we have uncovered a pathogenic function for fibroblastic stromal cells in alloimmune reactivity that can be dissociated from their homeostatic functions. Our results reveal what we believe to be a previously unrecognized Notch-mediated immunopathogenic role for stromal cell niches in secondary lymphoid organs after allo-BMT and define a framework of early cellular and molecular interactions that regulate T cell alloimmunity., Introduction Allogeneic bone marrow transplantation (allo-BMT) can cure hematological malignancies and other blood disorders. However, alloimmune T cell responses arising against foreign tissue antigens can trigger major complications such as [...]

Published
2017
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37. Phase II Study of Myeloablative 8/8- or 7/8-Matched Allotransplantation with Post-Transplant Cyclophosphamide, Tacrolimus, and Mycophenolate Mofetil: Marked Reduction in Gvhd Risk without Increased Relapse Risk Compared to Historical Cyclosporine/Methotrexate

Author

Hoover, Alex, primary, O'Leary, Daniel, additional, Cao, Qing, additional, Gupta, Ashish O., additional, Ebens, Christen L., additional, Maakaron, Joseph E., additional, Betts, Brian C., additional, Juckett, Mark, additional, Lund, Troy C., additional, Bachanova, Veronika, additional, MacMillan, Margaret L., additional, Miller, MD, Jeffrey S., additional, Orchard, Paul J., additional, Wagner, John E, additional, Vercellotti, Gregory M., additional, Weisdorf, Daniel J., additional, Dusenbery, Kathryn, additional, Terezakis, Stephanie, additional, Holtan, Shernan G, additional, and El Jurdi, Najla H, additional

Published
2022
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38. Impact of pre-transplant induction and consolidation cycles on AML allogeneic transplant outcomes: a CIBMTR analysis in 3113 AML patients

Author

Boyiadzis, Michael, primary, Zhang, Mei-Jie, additional, Chen, Karen, additional, Abdel-Azim, Hisham, additional, Abid, Muhammad Bilal, additional, Aljurf, Mahmoud, additional, Bacher, Ulrike, additional, Badar, Talha, additional, Badawy, Sherif M., additional, Battiwalla, Minoo, additional, Bejanyan, Nelli, additional, Bhatt, Vijaya Raj, additional, Brown, Valerie I., additional, Castillo, Paul, additional, Cerny, Jan, additional, Copelan, Edward A., additional, Craddock, Charles, additional, Dholaria, Bhagirathbhai, additional, Perez, Miguel Angel Diaz, additional, Ebens, Christen L., additional, Gale, Robert Peter, additional, Ganguly, Siddhartha, additional, Gowda, Lohith, additional, Grunwald, Michael R., additional, Hashmi, Shahrukh, additional, Hildebrandt, Gerhard C., additional, Iqbal, Madiha, additional, Jamy, Omer, additional, Kharfan-Dabaja, Mohamed A., additional, Khera, Nandita, additional, Lazarus, Hillard M., additional, Lin, Richard, additional, Modi, Dipenkumar, additional, Nathan, Sunita, additional, Nishihori, Taiga, additional, Patel, Sagar S., additional, Pawarode, Attaphol, additional, Sharma, Akshay, additional, Solh, Melhem, additional, Wagner, John L., additional, Wang, Trent, additional, Williams, Kirsten M., additional, Winestone, Lena E., additional, Wirk, Baldeep, additional, Hourigan, Christopher S., additional, Litzow, Mark, additional, Kebriaei, Partow, additional, de Lima, Marcos, additional, Page, Kristin, additional, and Weisdorf, Daniel J., additional

Published
2022
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39. 116 - Event Free Survival in Severe Combined Immune Deficiency (SCID) Infants after Conditioned Umbilical Cord Blood Transplantation (UCBT) Benefits from Omitting Serotherapy

Author

Martinez, Caridad, Logan, Brent, Liu, Xuerong, Dvorak, Christopher C., Madden, Lisa, Molinari, Lyndsay, Cowan, Morton J., Pai, Sung-Yun, Haddad, Elie, Puck, Jennifer, Kohn, Donald B., Griffith, Linda M., Pulsipher, Michael, Leiding, Jennifer W., Notarangelo, Luigi D., Torgerson, Troy, Marsh, Rebecca A., Cuvelier, Geoff D.E., Prockop, Susan, Buckley, Rebecca H., Kuo, Caroline Y., Yip, Alison, Hershfield, Michael S., Parrott, Roberta E, Ebens, Christen L., Moore, Theodore B., O’Reilly, Richard J., Kapadia, Malika, Kapoor, Neena, Satter, Lisa Forbes, Burroughs, Lauri M., Petrovic, Aleksandra, Thakar, Monica S., Chellapandian, Deepak, Heimall, Jennifer R., Shyr, David C., Bednarski, Jeffrey J, Rayes, Ahmad, Chandrakasan, Shanmuganathan, Quigg, Troy C., Davila, Blachy J, DeSantes, Kenneth, Eissa, Hesham, Goldman, Frederick, Rozmus, Jacob, Shah, Ami J, Lugt, Mark Vander, Keller, Michael D., Sullivan, Kathleen E., Jyonouchi, Soma, Seroogy, Christine, Decaluwe, Helene, Teira, Pierre, Knutsen, Alan P., Kletzel, Morris, Aquino, Victor, Davis, Jeffrey H, and Szabolcs, Paul

Published
2023
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41. Enhanced TH17 Responses in Patients with IL10 Receptor Deficiency and Infantile-onset IBD

Author

Shouval, Dror S., Konnikova, Liza, Griffith, Alexandra E., Wall, Sarah M., Biswas, Amlan, Werner, Lael, Nunberg, Moran, Kammermeier, Jochen, Goettel, Jeremy A., Anand, Rajsavi, Chen, Hannah, Weiss, Batia, Li, Jian, Loizides, Anthony, Yerushalmi, Baruch, Yanagi, Tadahiro, Beier, Rita, Conklin, Laurie S., Ebens, Christen L., Santos, Fernanda G. M. S., Sherlock, Mary, Goldsmith, Jeffery D., Kotlarz, Daniel, Glover, Sarah C., Shah, Neil, Bousvaros, Athos, Uhlig, Holm H., Muise, Aleixo M., Klein, Christoph, and Snapper, Scott B.

Published
2017
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42. 125 - Hematopoietic Cell Transplantation in 240 Patients with Chronic Granulomatous Disease: A Pidtc Report

Author

Arnold, Danielle E., Parikh, Suhag, Logan, Brent, Marsh, Rebecca, Griffith, Linda M., Wu, Ruizhe, Mallhi, Kanwaldeep, Chellapandian, Deepak, Si, Stephanie, Grunebaum, Eyal, Broglie, Larisa, Prasad, Vinod K., Heimall, Jennifer, Bunin, Nancy J., Teira, Pierre, Touzot, Fabien, Burroughs, Lauri M., Petrovic, Aleksandra, Bleesing, Jack J., Chandra, Sharat, Kapoor, Neena, Dara, Jasmeen, Dorsey, Morna, Williams, Olatundun, Kapadia, Malika, Bednarski, Jeffrey, Rayes, Ahmad, Chen, Karin, Chong, Hey, Cuvelier, Geoff D.E., Forbes, Lisa R., Martinez, Caridad, Vander Lugt, Mark T., Yu, Lolie C., Chandrakasan, Shanmuganathan, Joshi, Avni, Prockop, Susan E., Davila Saldana, Blachy J., Aquino, Victor, Ebens, Christen L., Madden, Lisa, DeSantes, Kenneth, Milner, Jordan, Rangarajan, Hemalatha G., Shah, Ami J, Gillio, Alfred P., Knutsen, Alan P., Miller, Holly K., Moore, Theodore B., Wright, Nicola, Cowan, Morton J., Dvorak, Christopher C., Haddad, Elie, Kohn, Donald B., Notarangelo, Luigi D., Pai, Sung-Yun, Puck, Jennifer, Pulsipher, Mike A., Torgerson, Troy, Malech, Harry L., Kang, Elizabeth M., and Leiding, Jennifer W.

Published
2022
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43. Outcomes after Hematopoietic Cell Transplant and Gene Therapy for Adenosine Deaminase (ADA) Severe Combined Immune Deficiency: A Combined Analysis from the Primary Immune Deficiency Treatment Consortium (PIDTC) 6901 and 6902 Studies

Author

Cuvelier, Geoff D.E., primary, Logan, Brent, additional, Prockop, Susan E., additional, Buckley, Rebecca H., additional, Kuo, Caroline Y., additional, Griffith, Linda M., additional, Liu, Xuerong, additional, Yip, Alison, additional, Hershfield, Michael S., additional, Parrott, Roberta E, additional, Ebens, Christen L., additional, Moore, Theodore B., additional, O’Reilly, Richard J., additional, Pai, Sung-Yun, additional, Kapadia, Malika, additional, Kapoor, Neena, additional, Forbes Satter, Lisa R., additional, Martinez, Caridad, additional, Burroughs, Lauri M., additional, Petrovic, Aleksandra, additional, Thakar, Monica S., additional, Chellapandian, Deepak, additional, Heimall, Jennifer, additional, Shyr, David C., additional, Rayes, Ahmad, additional, Bednarski II, Jeffrey J., additional, Chandra, Sharat, additional, Chandrakasan, Shanmuganathan, additional, Gillio, Alfred P., additional, Madden, Lisa, additional, Quigg, Troy C., additional, Caywood, Emi H., additional, Dávila Saldaña, Blachy J, additional, DeSantes, Kenneth, additional, Eissa, Hesham, additional, Goldman, Frederick, additional, Rozmus, Jacob, additional, Shah, Ami J, additional, Vander Lugt, Mark T., additional, Pulsipher, Mike A., additional, Notarangelo, Luigi D., additional, Cowan, Morton J., additional, Dvorak, Christopher C., additional, Haddad, Elie, additional, Puck, Jennifer, additional, and Kohn, Donald B., additional

Published
2022
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44. Hematopoietic Cell Transplantation in 240 Patients with Chronic Granulomatous Disease: A Pidtc Report

Author

Arnold, Danielle E., primary, Parikh, Suhag, additional, Logan, Brent, additional, Marsh, Rebecca, additional, Griffith, Linda M., additional, Wu, Ruizhe, additional, Mallhi, Kanwaldeep, additional, Chellapandian, Deepak, additional, Si, Stephanie, additional, Grunebaum, Eyal, additional, Broglie, Larisa, additional, Prasad, Vinod K., additional, Heimall, Jennifer, additional, Bunin, Nancy J., additional, Teira, Pierre, additional, Touzot, Fabien, additional, Burroughs, Lauri M., additional, Petrovic, Aleksandra, additional, Bleesing, Jack J., additional, Chandra, Sharat, additional, Kapoor, Neena, additional, Dara, Jasmeen, additional, Dorsey, Morna, additional, Williams, Olatundun, additional, Kapadia, Malika, additional, Bednarski, Jeffrey, additional, Rayes, Ahmad, additional, Chen, Karin, additional, Chong, Hey, additional, Cuvelier, Geoff D.E., additional, Forbes, Lisa R., additional, Martinez, Caridad, additional, Vander Lugt, Mark T., additional, Yu, Lolie C., additional, Chandrakasan, Shanmuganathan, additional, Joshi, Avni, additional, Prockop, Susan E., additional, Davila Saldana, Blachy J., additional, Aquino, Victor, additional, Ebens, Christen L., additional, Madden, Lisa, additional, DeSantes, Kenneth, additional, Milner, Jordan, additional, Rangarajan, Hemalatha G., additional, Shah, Ami J, additional, Gillio, Alfred P., additional, Knutsen, Alan P., additional, Miller, Holly K., additional, Moore, Theodore B., additional, Wright, Nicola, additional, Cowan, Morton J., additional, Dvorak, Christopher C., additional, Haddad, Elie, additional, Kohn, Donald B., additional, Notarangelo, Luigi D., additional, Pai, Sung-Yun, additional, Puck, Jennifer, additional, Pulsipher, Mike A., additional, Torgerson, Troy, additional, Malech, Harry L., additional, Kang, Elizabeth M., additional, and Leiding, Jennifer W., additional

Published
2022
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45. Low Incidence of Chronic Graft-Versus-Host Disease in Myeloablative Allogeneic Hematopoietic Cell Transplantation with Post-Transplant Cyclophosphamide Using Matched Related or Unrelated Donors: Phase II Study Interim Analysis

Author

El Jurdi, Najla, primary, O’Leary, Daniel, additional, He, Fiona, additional, DeFor, Todd E, additional, Rashidi, Armin, additional, Warlick, Erica, additional, Gupta, Ashish, additional, Maakaron, Joseph E., additional, Arora, Mukta, additional, Janakiram, Murali, additional, Slungaard, Arne, additional, Smith, Angela R., additional, Bachanova, Veronika, additional, Brunstein, Claudio G., additional, MacMillan, Margaret L., additional, Miller, Jeffrey S., additional, Betts, Brian C., additional, Ebens, Christen L., additional, Stefanski, Heather E, additional, Lund, Troy C, additional, Orchard, Paul J., additional, Vercellotti, Gregory M, additional, Weisdorf, Daniel, additional, and Holtan, Shernan, additional

Published
2022
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46. Third-Party Virus-Specific T-Cell Infusion for the Treatment of Refractory Viral Infections: Results from PBMTC SUP1701

Author

Keller, Michael D., primary, Hanley, Patrick J., additional, Tanna, Jay, additional, Jensen-Wachspress, Mariah, additional, Lang, Haili, additional, Aguayo-Hiraldo, Paibel, additional, Quigg, Troy C., additional, Verneris, Michael R., additional, Parikh, Suhag, additional, Dvorak, Christopher C., additional, Satwani, Prakash, additional, Davila-Saldana, Blachy, additional, Bednarski II, Jeffrey J., additional, Pai, Sung-Yun, additional, Whangbo, Jennifer, additional, Chandrakasan, Shanmuganathan, additional, Shereck, Evan, additional, Agarwal, Rajni, additional, Aquino, Victor, additional, Ebens, Christen L., additional, Dahlberg, Ann, additional, Gourdine, Liz, additional, Bollard, Catherine M., additional, and Pulsipher, Mike A., additional

Published
2022
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47. A Primary Immune Deficiency Treatment Consortium (PIDTC) Study of Chronic and Late Onset Medical Complications after Initial Hematopoietic Cell Transplantation (HCT) for Severe Combined Immunodeficiency Disease (SCID)

Author

Eissa, Hesham, primary, Thakar, Monica S., additional, Shah, Ami J, additional, Buckley, Rebecca H., additional, Logan, Brent, additional, Griffith, Linda M., additional, Dong, Huaying, additional, O’Reilly, Richard J., additional, Kapoor, Neena, additional, Satter, Lisa Forbes, additional, Chandra, Sharat, additional, Bleesing, Jack J., additional, Kapadia, Malika, additional, Parrott, Roberta E, additional, Chandrakasan, Shanmuganathan, additional, Bednarski II, Jeffrey J., additional, Jyonouchi, Soma, additional, Madden, Lisa M., additional, Rayes, Ahmad, additional, Ebens, Christen L., additional, Teira, Pierre, additional, Dávila Saldaña, Blachy J, additional, Burroughs, Lauri M., additional, Prockop, Susan E., additional, Williams, Olatundun, additional, Chellapandian, Deepak, additional, Gillio, Alfred P., additional, Goldman, Frederick, additional, Malech, Harry L., additional, DeSantes, Kenneth, additional, Cuvelier, Geoff D.E., additional, Rozmus, Jacob, additional, Quinones, Ralph, additional, Yu, Lolie C., additional, Broglie, Larisa, additional, Aquino, Victor, additional, Shereck, Evan, additional, Moore, Theodore B., additional, Martinez, Caridad, additional, Vander Lugt, Mark T., additional, Leiding, Jennifer W., additional, Torgerson, Troy, additional, Pai, Sung-Yun, additional, Pulsipher, Mike A., additional, Notarangelo, Luigi D., additional, Puck, Jennifer, additional, Dvorak, Christopher C., additional, Haddad, Elie, additional, Cowan, Morton J., additional, and Heimall, Jennifer, additional

Published
2022
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49. Clinical trial of ABCB5+ mesenchymal stem cells for recessive dystrophic epidermolysis bullosa

Author

Kiritsi, Dimitra, primary, Dieter, Kathrin, additional, Niebergall-Roth, Elke, additional, Fluhr, Silvia, additional, Daniele, Cristina, additional, Esterlechner, Jasmina, additional, Sadeghi, Samar, additional, Ballikaya, Seda, additional, Erdinger, Leoni, additional, Schauer, Franziska, additional, Gewert, Stella, additional, Laimer, Martin, additional, Bauer, Johann W., additional, Hovnanian, Alain, additional, Zambruno, Giovanna, additional, El Hachem, May, additional, Bourrat, Emmanuelle, additional, Papanikolaou, Maria, additional, Petrof, Gabriela, additional, Kitzmüller, Sophie, additional, Ebens, Christen L., additional, Frank, Markus H., additional, Frank, Natasha Y., additional, Ganss, Christoph, additional, Martinez, Anna E., additional, McGrath, John A., additional, Tolar, Jakub, additional, and Kluth, Mark A., additional

Published
2021
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