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6 results on '"Ede, Kaleo C."'

1. Distinguishing Multisystem Inflammatory Syndrome in Children From COVID-19, Kawasaki Disease and Toxic Shock Syndrome

Author

Godfred-Cato, Shana, Abrams, Joseph Y., Balachandran, Neha, Jaggi, Preeti, Jones, Kaitlin, Rostad, Christina A., Lu, Austin T., Fan, Lucie, Jabbar, Aysha, Anderson, Evan J., Kao, Carol M., Hunstad, David A., Rosenberg, Robert B., Zafferani, Marc J., Ede, Kaleo C., Ballan, Wassim, Laham, Federico R., Beltran, Yajira, Bryant, Bobbi, Meng, Lu, Hammett, Teresa A., Oster, Matthew E., Bamrah Morris, Sapna, and Belay, Ermias D.

Published
2022
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2. Serologic and Cytokine Signatures in Children With Multisystem Inflammatory Syndrome and Coronavirus Disease 2019

Author

Lapp, Stacey A, primary, Abrams, Joseph, additional, Lu, Austin T, additional, Hussaini, Laila, additional, Kao, Carol M, additional, Hunstad, David A, additional, Rosenberg, Robert B, additional, Zafferani, Marc J, additional, Ede, Kaleo C, additional, Ballan, Wassim, additional, Laham, Federico R, additional, Beltran, Yajira, additional, Hsiao, Hui-Mien, additional, Sherry, Whitney, additional, Jenkins, Elan, additional, Jones, Kaitlin, additional, Horner, Anna, additional, Brooks, Alyssa, additional, Bryant, Bobbi, additional, Meng, Lu, additional, Hammett, Teresa A, additional, Oster, Matthew E, additional, Bamrah-Morris, Sapna, additional, Godfred-Cato, Shana, additional, Belay, Ermias, additional, Chahroudi, Ann, additional, Anderson, Evan J, additional, Jaggi, Preeti, additional, and Rostad, Christina A, additional

Published
2022
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4. Preliminary evidence on abatacept safety and efficacy in refractory juvenile localized scleroderma.

Author

Li, Suzanne C, Torok, Kathryn S, Ishaq, Sarah S, Buckley, Mary, Edelheit, Barbara, Ede, Kaleo C, Liu, Christopher, and Rabinovich, C Egla

Subjects
DRUG efficacy, RESEARCH, GLUCOCORTICOIDS, MEDICAL cooperation, RETROSPECTIVE studies, MYCOPHENOLIC acid, TREATMENT failure, ANTIRHEUMATIC agents, DESCRIPTIVE statistics, SCLERODERMA (Disease), ABATACEPT, PATIENT safety, LONGITUDINAL method
Abstract

Objective To evaluate the safety and efficacy of abatacept treatment for refractory juvenile localized scleroderma (jLS) in a retrospective study. Methods A multicentre cohort study was performed to evaluate jLS subjects treated with abatacept with follow-up for 12 months to maximum of 24 months. Assessments at 6-month intervals included skin activity measures and physician global assessment of activity (PGA-A). Descriptive statistical analysis was performed. Results Eighteen subjects were studied with median age of 13.4 years, the majority had linear scleroderma subtype, and musculoskeletal involvement. All had previously failed MTX and/or mycophenolate mofetil treatment and glucocorticoids. Abatacept was added to the subject's maintenance DMARD treatment; 13 also received glucocorticoids at start of abatacept. No serious adverse events occurred. Skin activity and PGA-A scores declined in nearly all by 6 months and continued to improve from 6 to 12 months. At 12 months, 15 (83%) subjects were considered responders, two (11%) treatment failures, and one dropped out for adverse event. Response was sustained for 11 (61%) subjects to 18 months and eight (44%) to 24 months. Overall, four (22%) subjects were treatment failures and three (16.7%) discontinued abatacept for adverse event. Active musculoskeletal problems improved in most affected subjects. Ten subjects were able to discontinue initial glucocorticoid and six concomitant DMARD treatment. Conclusion Abatacept was found to be safe and effective for jLS subjects refractory to standard of care treatment. Subjects experienced improvement in both skin and musculoskeletal activity. Prospective studies should be performed to more fully evaluate abatacept's efficacy. [ABSTRACT FROM AUTHOR]

Published
2021
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5. Serum S100A8/A9 and S100A12 Levels in Children With Polyarticular Forms of Juvenile Idiopathic Arthritis: Relationship to Maintenance of Clinically Inactive Disease During Anti–Tumor Necrosis Factor Therapy and Occurrence of Disease Flare After Discontinuation of Therapy

Author

Hinze, Claas H., primary, Foell, Dirk, additional, Johnson, Anne L., additional, Spalding, Steven J., additional, Gottlieb, Beth S., additional, Morris, Paula W., additional, Kimura, Yukiko, additional, Onel, Karen, additional, Li, Suzanne C., additional, Grom, Alexei A., additional, Taylor, Janalee, additional, Brunner, Hermine I., additional, Huggins, Jennifer L., additional, Nocton, James J., additional, Haines, Kathleen A., additional, Edelheit, Barbara S., additional, Shishov, Michael, additional, Jung, Lawrence K., additional, Williams, Calvin B., additional, Tesher, Melissa S., additional, Costanzo, Denise M., additional, Zemel, Lawrence S., additional, Dare, Jason A., additional, Passo, Murray H., additional, Ede, Kaleo C., additional, Olson, Judyann C., additional, Cassidy, Elaine A., additional, Griffin, Thomas A., additional, Wagner‐Weiner, Linda, additional, Weiss, Jennifer E., additional, Vogler, Larry B., additional, Rouster‐Stevens, Kelly A., additional, Beukelman, Timothy, additional, Cron, Randy Q., additional, Kietz, Daniel, additional, Schikler, Kenneth, additional, Mehta, Jay, additional, Ting, Tracy V., additional, Verbsky, James W., additional, Eberhard, Anne B., additional, Huang, Bin, additional, Giannini, Edward H., additional, and Lovell, Daniel J., additional

Published
2019
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6. Risk, Timing, and Predictors of Disease Flare After Discontinuation of Anti-Tumor Necrosis Factor Therapy in Children With Polyarticular Forms of Juvenile Idiopathic Arthritis With Clinically Inactive Disease

Author

Lovell, Daniel J., primary, Johnson, Anne L., additional, Huang, Bin, additional, Gottlieb, Beth S., additional, Morris, Paula W., additional, Kimura, Yukiko, additional, Onel, Karen, additional, Li, Suzanne C., additional, Grom, Alexei A., additional, Taylor, Janalee, additional, Brunner, Hermine I., additional, Huggins, Jennifer L., additional, Nocton, James J., additional, Haines, Kathleen A., additional, Edelheit, Barbara S., additional, Shishov, Michael, additional, Jung, Lawrence K., additional, Williams, Calvin B., additional, Tesher, Melissa S., additional, Costanzo, Denise M., additional, Zemel, Lawrence S., additional, Dare, Jason A., additional, Passo, Murray H., additional, Ede, Kaleo C., additional, Olson, Judyann C., additional, Cassidy, Elaine A., additional, Griffin, Thomas A., additional, Wagner-Weiner, Linda, additional, Weiss, Jennifer E., additional, Vogler, Larry B., additional, Rouster-Stevens, Kelly A., additional, Beukelman, Timothy, additional, Cron, Randy Q., additional, Kietz, Daniel, additional, Schikler, Kenneth, additional, Schmidt, Kara M., additional, Mehta, Jay, additional, Wahezi, Dawn M., additional, Ting, Tracy V., additional, Verbsky, James W., additional, Eberhard, B. Anne, additional, Spalding, Steven, additional, Chen, Chen, additional, and Giannini, Edward H., additional

Published
2018
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