400 results on '"Edenhofer, Frank"'
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2. Modeling early phenotypes of Parkinson’s disease by age-induced midbrain-striatum assembloids
3. Single-cell Profiling of Reprogrammed Human Neural Stem Cells Unveils High Similarity to Neural Progenitors in the Developing Central Nervous System
4. Increased cholesterol synthesis drives neurotoxicity in patient stem cell-derived model of multiple sclerosis
5. Truncated variants of MAGEL2 are involved in the etiologies of the Schaaf-Yang and Prader-Willi syndromes
6. Recommendations, guidelines, and best practice for the use of human induced pluripotent stem cells for neuropharmacological studies of neuropsychiatric disorders
7. Benchmarking second-generation methods for cell-type deconvolution of transcriptomic data
8. Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer’s patients
9. Functionally distinct POMC-expressing neuron subpopulations in hypothalamus revealed by intersectional targeting
10. Combination of In Situ Lcn2 pRNA-RNAi Nanotherapeutics and iNSC Transplantation Ameliorates Experimental SCI in Mice
11. Generation of the human induced pluripotent stem cell line (IBKMOLi003-A) from PBMCs of a vascular Ehlers-Danlos syndrome (vEDS) patient carrying the heterozygous nonsense mutation c.430C > T (p.Q105*) in the COL3A1 gene
12. Serotonin-specific neurons differentiated from human iPSCs form distinct subtypes with synaptic protein assembly
13. iPS-abgeleitete Kardiomyozyten als therapeutische Hoffnungsträger
14. Integrative single-cell analysis of neural stem/progenitor cells reveals epigenetically dysregulated interferon response in progressive multiple sclerosis
15. Increased Cholesterol Synthesis Drives Neurotoxicity in Patient Stem Cell-Derived Model of Multiple Sclerosis
16. Small fibre neuropathy in Fabry disease: a human-derived neuronal in vitro disease model and pilot data
17. Identification of Embryonic Neural Plate Border Stem Cells and Their Generation by Direct Reprogramming from Adult Human Blood Cells
18. Metabolic substrate shift in human induced pluripotent stem cells during cardiac differentiation: Functional assessment using in vitro radionuclide uptake assay
19. Macrophage-Derived Extracellular Succinate Licenses Neural Stem Cells to Suppress Chronic Neuroinflammation
20. Age-induced midbrain-striatum assembloids model early phenotypes of Parkinson’s disease
21. The promise of genetic screens in human in vitro brain models
22. Ability of the Hydrophobic FGF and Basic TAT Peptides to Promote Cellular Uptake of Recombinant Cre Recombinase: A Tool for Efficient Genetic Engineering of Mammalian Genomes
23. Establishment of a Human Blood-Brain Barrier Co-culture Model Mimicking the Neurovascular Unit Using Induced Pluri- and Multipotent Stem Cells
24. The vascular adventitia: An endogenous, omnipresent source of stem cells in the body
25. Transplantation of induced neural stem cells (iNSCs) into chronically demyelinated corpus callosum ameliorates motor deficits
26. A genome-scale map of DNA methylation turnover identifies site-specific dependencies of DNMT and TET activity
27. Small fibre neuropathy in Fabry disease: a human-derived neuronal in vitro disease model
28. Partial Dedifferentiation of Murine Radial Glia-Type Neural Stem Cells by Brn2 and c-Myc Yields Early Neuroepithelial Progenitors
29. Myc Depletion Induces a Pluripotent Dormant State Mimicking Diapause
30. The promise of genetic screens in human in vitro brain models.
31. Integrative metabolomics-genomics analysis identifies key networks in a stem cell-based model of schizophrenia.
32. Cell-permeant recombinant Nanog protein promotes pluripotency by inhibiting endodermal specification
33. Stem cell technology
34. Generation of Cardiomyocytes From Vascular Adventitia-Resident Stem Cells
35. Characterization of a novel cell penetrating peptide derived from human Oct4
36. Need for high-resolution Genetic Analysis in iPSC: Results and Lessons from the ForIPS Consortium
37. Emerging Role of miR-21-5p in Neuron–Glia Dysregulation and Exosome Transfer Using Multiple Models of Alzheimer’s Disease
38. A LewisX Glycoprotein Screen Identifies the Low Density Lipoprotein Receptor-related Protein 1 (LRP1) as a Modulator of Oligodendrogenesis in Mice
39. Emerging role of miR-21-5p in neuron-glia dysregulation and exosome transfer using multi-models of Alzheimer's disease - Supplementary data
40. Quantification of cell fusion events human breast cancer cells and breast epithelial cells using a Cre-LoxP-based double fluorescence reporter system
41. Robust Generation of Cardiomyocytes from Human iPS Cells Requires Precise Modulation of BMP and WNT Signaling
42. ADHD‐associated PARK2 copy number variants: A pilot study on gene expression and effects of supplementary deprivation in patient‐derived cell lines
43. Genetic engineering of mammalian cells by direct delivery of FLP recombinase protein
44. Generation of the human induced pluripotent stem cell line (IBKMOLi002-A) from PBMCs of a patient carrying the heterozygous L271H mutation of the voltage-gated calcium channel subunit Cav1.3-encoding CACNA1D gene
45. Peroxisome Proliferator-Activated Receptor (PPAR)γ Can Inhibit Chronic Renal Allograft Damage
46. Targeting α-Synuclein in Parkinson's Disease by Induced Pluripotent Stem Cell Models
47. Take the shortcut – direct conversion of somatic cells into induced neural stem cells and their biomedical applications
48. Next‐generation disease modeling with direct conversion: a new path to old neurons
49. High Glycolytic Activity Enhances Stem Cell Reprogramming of Fahd1-KO Mouse Embryonic Fibroblasts
50. Autophagy in α-Synucleinopathies—An Overstrained System
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