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4. R‐ketorolac ameliorates cancer‐associated cachexia and prolongs survival of tumour‐bearing mice

Author

Chrysostomou, Sophia E., primary, Eder, Sandra, additional, Pototschnig, Isabella, additional, Mayer, Anna‐Lena, additional, Derler, Martina, additional, Mussbacher, Marion, additional, Schauer, Silvia, additional, Zhang, Dongxu, additional, Yan, Dongmei, additional, Liu, Gennie, additional, Hoefler, Gerald, additional, Weichhart, Thomas, additional, Vesely, Paul W., additional, Zhang, Lingbing, additional, and Schweiger, Martina, additional

Published
2024
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6. Advanced lipodystrophy reverses fatty liver in mice lacking adipocyte hormone-sensitive lipase

Author

Pajed, Laura, Taschler, Ulrike, Tilp, Anna, Hofer, Peter, Kotzbeck, Petra, Kolleritsch, Stephanie, Radner, Franz P. W., Pototschnig, Isabella, Wagner, Carina, Schratter, Margarita, Eder, Sandra, Huetter, Sabrina, Schreiber, Renate, Haemmerle, Guenter, Eichmann, Thomas O., Schweiger, Martina, Hoefler, Gerald, Kershaw, Erin E., Lass, Achim, and Schoiswohl, Gabriele

Published
2021
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9. Marketing a Resource and Referral Resource Room to Child Care Providers and Parents.

Author

Eder, Sandra

Abstract

Recognizing the importance of providing parents and child care providers with current information on early childhood education, care, and support, this practicum project evaluated the design and implementation of a 10-week strategy to market a child care resource and referral agency resource room to child care providers and parents. Observations, surveys, questionnaires, and interviews were used to document the low use of the resource room by staff and the lack of parent knowledge regarding the room's existence. The strategies used to market the resource room included creating a staff committee with diverse interests to take responsibility for marketing, maintaining, and displaying the resource room; informing parents about the resource room when they called the agency; marketing through media such as brochures, newsletters, and displays set up in community libraries or bulletin boards; and creating web pages to target corporate clients. Daily logs were used to record use of the resource room. Results suggest that the staff training was effective. Parents were informed about the resource when they called the service. Providers made great use of the room after they learned about its existence. Through marketing procedures, providers learned about new materials in the resource room and their utilization. They were likely to visit during newly extended hours. (Six appendices include the staff questionnaire, provider phone survey, resource center diagram, customer benefits, materials needed, and calendar implementation plan. Contains 11 references.) (Author/KB)

Published
1997

11. Data from Functional Precision Medicine Provides Clinical Benefit in Advanced Aggressive Hematologic Cancers and Identifies Exceptional Responders

Author

Kornauth, Christoph, primary, Pemovska, Tea, primary, Vladimer, Gregory I., primary, Bayer, Günther, primary, Bergmann, Michael, primary, Eder, Sandra, primary, Eichner, Ruth, primary, Erl, Martin, primary, Esterbauer, Harald, primary, Exner, Ruth, primary, Felsleitner-Hauer, Verena, primary, Forte, Maurizio, primary, Gaiger, Alexander, primary, Geissler, Klaus, primary, Greinix, Hildegard T., primary, Gstöttner, Wolfgang, primary, Hacker, Marcus, primary, Hartmann, Bernd Lorenz, primary, Hauswirth, Alexander W., primary, Heinemann, Tim, primary, Heintel, Daniel, primary, Hoda, Mir Alireza, primary, Hopfinger, Georg, primary, Jaeger, Ulrich, primary, Kazianka, Lukas, primary, Kenner, Lukas, primary, Kiesewetter, Barbara, primary, Krall, Nikolaus, primary, Krajnik, Gerhard, primary, Kubicek, Stefan, primary, Le, Trang, primary, Lubowitzki, Simone, primary, Mayerhoefer, Marius E., primary, Menschel, Elisabeth, primary, Merkel, Olaf, primary, Miura, Katsuhiro, primary, Müllauer, Leonhard, primary, Neumeister, Peter, primary, Noesslinger, Thomas, primary, Ocko, Katharina, primary, Öhler, Leopold, primary, Panny, Michael, primary, Pichler, Alexander, primary, Porpaczy, Edit, primary, Prager, Gerald W., primary, Raderer, Markus, primary, Ristl, Robin, primary, Ruckser, Reinhard, primary, Salamon, Julius, primary, Schiefer, Ana-Iris, primary, Schmolke, Ann-Sofie, primary, Schwarzinger, Ilse, primary, Selzer, Edgar, primary, Sillaber, Christian, primary, Skrabs, Cathrin, primary, Sperr, Wolfgang R., primary, Srndic, Ismet, primary, Thalhammer, Renate, primary, Valent, Peter, primary, van der Kouwe, Emiel, primary, Vanura, Katrina, primary, Vogt, Stefan, primary, Waldstein, Cora, primary, Wolf, Dominik, primary, Zielinski, Christoph C., primary, Zojer, Niklas, primary, Simonitsch-Klupp, Ingrid, primary, Superti-Furga, Giulio, primary, Snijder, Berend, primary, and Staber, Philipp B., primary

Published
2023
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12. Supplementary Data from Functional Precision Medicine Provides Clinical Benefit in Advanced Aggressive Hematologic Cancers and Identifies Exceptional Responders

Author

Kornauth, Christoph, primary, Pemovska, Tea, primary, Vladimer, Gregory I., primary, Bayer, Günther, primary, Bergmann, Michael, primary, Eder, Sandra, primary, Eichner, Ruth, primary, Erl, Martin, primary, Esterbauer, Harald, primary, Exner, Ruth, primary, Felsleitner-Hauer, Verena, primary, Forte, Maurizio, primary, Gaiger, Alexander, primary, Geissler, Klaus, primary, Greinix, Hildegard T., primary, Gstöttner, Wolfgang, primary, Hacker, Marcus, primary, Hartmann, Bernd Lorenz, primary, Hauswirth, Alexander W., primary, Heinemann, Tim, primary, Heintel, Daniel, primary, Hoda, Mir Alireza, primary, Hopfinger, Georg, primary, Jaeger, Ulrich, primary, Kazianka, Lukas, primary, Kenner, Lukas, primary, Kiesewetter, Barbara, primary, Krall, Nikolaus, primary, Krajnik, Gerhard, primary, Kubicek, Stefan, primary, Le, Trang, primary, Lubowitzki, Simone, primary, Mayerhoefer, Marius E., primary, Menschel, Elisabeth, primary, Merkel, Olaf, primary, Miura, Katsuhiro, primary, Müllauer, Leonhard, primary, Neumeister, Peter, primary, Noesslinger, Thomas, primary, Ocko, Katharina, primary, Öhler, Leopold, primary, Panny, Michael, primary, Pichler, Alexander, primary, Porpaczy, Edit, primary, Prager, Gerald W., primary, Raderer, Markus, primary, Ristl, Robin, primary, Ruckser, Reinhard, primary, Salamon, Julius, primary, Schiefer, Ana-Iris, primary, Schmolke, Ann-Sofie, primary, Schwarzinger, Ilse, primary, Selzer, Edgar, primary, Sillaber, Christian, primary, Skrabs, Cathrin, primary, Sperr, Wolfgang R., primary, Srndic, Ismet, primary, Thalhammer, Renate, primary, Valent, Peter, primary, van der Kouwe, Emiel, primary, Vanura, Katrina, primary, Vogt, Stefan, primary, Waldstein, Cora, primary, Wolf, Dominik, primary, Zielinski, Christoph C., primary, Zojer, Niklas, primary, Simonitsch-Klupp, Ingrid, primary, Superti-Furga, Giulio, primary, Snijder, Berend, primary, and Staber, Philipp B., primary

Published
2023
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13. Electrospray Ionization Tandem Mass Spectrometry (ESI-MS/MS) Analysis of the Lipid Molecular Species Composition of Yeast Subcellular Membranes Reveals Acyl Chain-Based Sorting/Remodeling of Distinct Molecular Species En Route to the Plasma Membrane

Author

Schneiter, Roger, Brügger, Britta, Sandhoff, Roger, Zellnig, Günther, Leber, Andrea, Lampl, Manfred, Athenstaedt, Karin, Hrastnik, Claudia, Eder, Sandra, Daum, Günther, Paltauf, Fritz, Wieland, Felix T., and Kohlwein, Sepp D.

Published
1999

14. Fasting-induced G0/G1 switch gene 2 and FGF21 expression in the liver are under regulation of adipose tissue derived fatty acids

Author

Jaeger, Doris, Schoiswohl, Gabriele, Hofer, Peter, Schreiber, Renate, Schweiger, Martina, Eichmann, Thomas O., Pollak, Nina M., Poecher, Nadja, Grabner, Gernot F., Zierler, Kathrin A., Eder, Sandra, Kolb, Dagmar, Radner, Franz P.W., Preiss-Landl, Karina, Lass, Achim, Zechner, Rudolf, Kershaw, Erin E., and Haemmerle, Guenter

Published
2015
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17. Thiotepa‐based conditioning versus total body irradiation as myeloablative conditioning prior to allogeneic stem cell transplantation for acute lymphoblastic leukemia: A matched‐pair analysis from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation

Author

Eder, Sandra, Canaani, Jonathan, Beohou, Eric, Labopin, Myriam, Sanz, Jaime, Arcese, William, Or, Reuven, Finke, Juergen, Cortelezzi, Agostino, Beelen, Dietrich, Passweg, Jakob, Socié, Gerard, Gurman, Gunhan, Aljurf, Mahmoud, Stelljes, Matthias, Giebel, Sebastian, Mohty, Mohamad, and Nagler, Arnon

Published
2017
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34. Adiponutrin Functions as a Nutritionally Regulated Lysophosphatidic Acid Acyltransferase

Author

Kumari, Manju, Schoiswohl, Gabriele, Chitraju, Chandramohan, Paar, Margret, Cornaciu, Irina, Rangrez, Ashraf Y., Wongsiriroj, Nuttaporn, Nagy, Harald M., Ivanova, Pavlina T., Scott, Sarah A., Knittelfelder, Oskar, Rechberger, Gerald N., Birner-Gruenberger, Ruth, Eder, Sandra, Brown, H. Alex, Haemmerle, Guenter, Oberer, Monika, Lass, Achim, Kershaw, Erin E., Zimmermann, Robert, and Zechner, Rudolf

Published
2012
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38. Functional Precision Medicine Provides Clinical Benefit in Advanced Aggressive Hematologic Cancers and Identifies Exceptional Responders

Author

Kornauth, Christoph, primary, Pemovska, Tea, additional, Vladimer, Gregory I., additional, Bayer, Günther, additional, Bergmann, Michael, additional, Eder, Sandra, additional, Eichner, Ruth, additional, Erl, Martin, additional, Esterbauer, Harald, additional, Exner, Ruth, additional, Felsleitner-Hauer, Verena, additional, Forte, Maurizio, additional, Gaiger, Alexander, additional, Geissler, Klaus, additional, Greinix, Hildegard T., additional, Gstöttner, Wolfgang, additional, Hacker, Marcus, additional, Hartmann, Bernd Lorenz, additional, Hauswirth, Alexander W., additional, Heinemann, Tim, additional, Heintel, Daniel, additional, Hoda, Mir Alireza, additional, Hopfinger, Georg, additional, Jaeger, Ulrich, additional, Kazianka, Lukas, additional, Kenner, Lukas, additional, Kiesewetter, Barbara, additional, Krall, Nikolaus, additional, Krajnik, Gerhard, additional, Kubicek, Stefan, additional, Le, Trang, additional, Lubowitzki, Simone, additional, Mayerhoefer, Marius E., additional, Menschel, Elisabeth, additional, Merkel, Olaf, additional, Miura, Katsuhiro, additional, Müllauer, Leonhard, additional, Neumeister, Peter, additional, Noesslinger, Thomas, additional, Ocko, Katharina, additional, Öhler, Leopold, additional, Panny, Michael, additional, Pichler, Alexander, additional, Porpaczy, Edit, additional, Prager, Gerald W., additional, Raderer, Markus, additional, Ristl, Robin, additional, Ruckser, Reinhard, additional, Salamon, Julius, additional, Schiefer, Ana-Iris, additional, Schmolke, Ann-Sofie, additional, Schwarzinger, Ilse, additional, Selzer, Edgar, additional, Sillaber, Christian, additional, Skrabs, Cathrin, additional, Sperr, Wolfgang R., additional, Srndic, Ismet, additional, Thalhammer, Renate, additional, Valent, Peter, additional, van der Kouwe, Emiel, additional, Vanura, Katrina, additional, Vogt, Stefan, additional, Waldstein, Cora, additional, Wolf, Dominik, additional, Zielinski, Christoph C., additional, Zojer, Niklas, additional, Simonitsch-Klupp, Ingrid, additional, Superti-Furga, Giulio, additional, Snijder, Berend, additional, and Staber, Philipp B., additional

Published
2021
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39. Thiotepa-based versus total body irradiation-based myeloablative conditioning prior to allogeneic stem cell transplantation for acute myeloid leukaemia in first complete remission: a retrospective analysis from the Acute Leukemia Working Party of the European Group for Blood and Marrow Transplantation

Author

Eder, Sandra, Labopin, Myriam, Arcese, William, Or, Reuven, Majolino, Ignazio, Bacigalupo, Andrea, de Rosa, Gennaro, Volin, Liisa, Beelen, Dietrich, Veelken, Hendrik, Schaap, Nicolaas P. M., Kuball, Jurgen, Cornelissen, Jan, Nagler, Arnon, and Mohty, Mohamad

Published
2016
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42. Treatment Guided By Next Generation Functional Drug Screening Provides Clinical Benefit in Advanced Aggressive Hematological Malignancies: Final Evaluation of the Open Label, Single Arm Exalt Trial

Author

Kornauth, Christoph, primary, Pemovska, Tea, additional, Vladimer, Gregory Ian, additional, Bayer, Günther, additional, Bergmann, Michael, additional, Eder, Sandra, additional, Eichner, Ruth, additional, Esterbauer, Harald, additional, Exner, Ruth, additional, Felsleitner-Hauer, Verena, additional, Forte, Maurizio, additional, Gaiger, Alexander, additional, Greinix, Hildegard T., additional, Gstöttner, Wolfgang, additional, Hacker, Marcus, additional, Hauswirth, Alexander, additional, Heinemann, Tim, additional, Heintel, Daniel, additional, Hoda, Mir Ali Reza, additional, Jaeger, Ulrich, additional, Kazianka, Lukas, additional, Kenner, Lukas, additional, Kiesewetter, Barbara, additional, Krall, Nikolaus, additional, Le, Trang, additional, Lubowitzki, Simone, additional, Mayerhoefer, Marius E, additional, Menschel, Elisabeth, additional, Merkel, Olaf, additional, Miura, Katsuhiro, additional, Muellauer, Leonhard, additional, Neumeister, Peter, additional, Noesslinger, Thomas, additional, Ocko, Katharina, additional, Öhler, Leopold, additional, Panny, Michael, additional, Pichler, Alexander, additional, Porpaczy, Edit Anna, additional, Prager, Gerald, additional, Raderer, Markus, additional, Ristl, Robin, additional, Ruckser, Reinhard, additional, Salamon, Julius, additional, Schiefer, Ana-Iris, additional, Schmolke, Ann-Sofie, additional, Schwarzinger, Ilse, additional, Selzer, Edgar, additional, Skrabs, Cathrin, additional, Sperr, Wolfgang R., additional, Srndic, Ismet, additional, Thalhammer, Renate, additional, Valent, Peter, additional, van der Kouwe, Emiel, additional, Vanura, Katrina, additional, Vogt, Stefan, additional, Waldstein, Cora, additional, Wolf, Dominik, additional, Zielinski, Christoph, additional, Simonitsch-Klupp, Ingrid, additional, Superti-Furga, Giulio, additional, Snijder, Berend, additional, and Staber, Philipp B., additional

Published
2020
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43. Extracorporeal photopheresis as first-line strategy in the treatment of acute graft-versus-host disease after hematopoietic stem cell transplantation: A single-center experience

Author

Sestili, Simona, primary, Eder, Sandra, additional, Belhocine, Ramdane, additional, Dulery, Remy, additional, Battipaglia, Giorgia, additional, Brissot, Eolia, additional, Mediavilla, Clemence, additional, Banet, Anne, additional, van de Wyngaert, Zoe, additional, Paviglianiti, Annalisa, additional, Ledraa, Tounes, additional, Bonin, Agnes, additional, Mohty, Mohamad, additional, and Malard, Florent, additional

Published
2020
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45. Efficacy and feasibility of sorafenib as a maintenance agent after allogeneic hematopoietic stem cell transplantation for Fms-like tyrosine kinase 3-mutated acute myeloid leukemia

Author

Battipaglia, Giorgia, Ruggeri, Annalisa, Massoud, Radwan, El Cheikh, Jean, Jestin, Matthieu, Antar, Ahmad, Ahmed, Syed Osman, Rasheed, Walid, Shaheen, Marwan, Belhocine, Ramdane, Brissot, Eolia, Dulery, Remy, Eder, Sandra, Giannotti, Federica, Isnard, Françoise, Lapusan, Simona, Rubio, Marie-Thérèse, Vekhoff, Anne, Aljurf, Mahmoud, Legrand, Ollivier, Mohty, Mohamad, Bazarbachi, Ali, Service d'hématologie clinique et de thérapie cellulaire [CHU Saint-Antoine], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Saint-Antoine [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU), Università degli studi di Napoli Federico II, American University of Beirut Faculty of Medicine and Medical Center (AUB), King Faisal Specialist Hospital and Research Centre, Service d'Hématologie [CHRU Nancy], Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Ingénierie Moléculaire et Physiopathologie Articulaire (IMoPA), Centre National de la Recherche Scientifique (CNRS)-Université de Lorraine (UL), Battipaglia, G., Ruggeri, A., Massoud, R., El Cheikh, J., Jestin, M., Antar, A., Ahmed, S. O., Rasheed, W., Shaheen, M., Belhocine, R., Brissot, E., Dulery, R., Eder, S., Giannotti, F., Isnard, F., Lapusan, S., Rubio, M. -T., Vekhoff, A., Aljurf, M., Legrand, O., Mohty, M., and Bazarbachi, A.

Subjects
Adult, Male, Niacinamide, Phenylurea Compound, Fms-like tyrosine kinase 3 (FLT3), Adolescent, [SDV]Life Sciences [q-bio], Graft vs Host Disease, Antineoplastic Agents, Disease-Free Survival, maintenance, Maintenance Chemotherapy, Antineoplastic Agent, Young Adult, acute myeloid leukemia (AML), allogeneic stem cell transplantation, Retrospective Studie, Humans, Transplantation, Homologous, Transplantation, Homologou, ComputingMilieux_MISCELLANEOUS, Retrospective Studies, Phenylurea Compounds, Hematopoietic Stem Cell Transplantation, [SDV.MHEP.HEM]Life Sciences [q-bio]/Human health and pathology/Hematology, Middle Aged, Sorafenib, Feasibility Studie, Leukemia, Myeloid, Acute, Treatment Outcome, fms-Like Tyrosine Kinase 3, Chemotherapy, Adjuvant, Feasibility Studies, Female, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, Human
Abstract

BACKGROUND: Sorafenib has shown encouraging results in patients with Fms-like tyrosine kinase 3 (FLT3)-positive acute myeloid leukemia. Its role after allogeneic stem cell transplantation (HSCT) has been reported in a few cases with encouraging results. METHODS: The authors describe the use of sorafenib as a maintenance agent after HSCT in 27 patients with FLT3-positive acute myeloid leukemia. RESULTS: The median age of the patients was 46 years (range, 15-57 years). Sorafenib was introduced at a median of 70 days (range, 29-337 days) after HSCT. The median treatment duration was 8.4 months (range, 0.2-46 months). Eleven patients experienced treatment toxicities, mainly of grade 1 to 2 (graded according to the National Cancer Institute Common Toxicity Criteria [version 4.0]). Dose reduction or withdrawal was required in 4 patients and 4 patients, respectively. The persistence of toxicity prompted treatment withdrawal in 1 patient. Clinical improvement followed dose modifications. Thirteen patients experienced chronic graft-versus-host disease (limited in 9 patients and extensive in 4 patients), resulting in dose reduction in 5 patients followed by withdrawal in 1 of these individuals. At a median follow-up of 18 months (range, 4-48 months), 25 patients were alive (all of whom were in complete molecular remission) and 18 were still receiving treatment, with 1-year overall survival and progression-free survival rates of 92% ± 6% and 92% ± 5%, respectively. CONCLUSIONS: Sorafenib treatment after HSCT appears to be feasible and highly effective with dose individualization according to patient tolerability. Further analysis is needed to evaluate the immunomodulating role of sorafenib after HSCT. The data from the current support prospective controlled trials of sorafenib after HSCT. Cancer 2017;123:2867–74. © 2017 American Cancer Society.

Published
2017

46. Intestine‐Specific Overexpression of Carboxylesterase 2c Protects Mice From Diet‐Induced Liver Steatosis and Obesity

Author

Maresch, Lisa Katharina, primary, Benedikt, Pia, additional, Feiler, Ursula, additional, Eder, Sandra, additional, Zierler, Kathrin A., additional, Taschler, Ulrike, additional, Kolleritsch, Stephanie, additional, Eichmann, Thomas O., additional, Schoiswohl, Gabriele, additional, Leopold, Christina, additional, Wieser, Beatrix I., additional, Lackner, Caroline, additional, Rülicke, Thomas, additional, van Klinken, Jan, additional, Kratky, Dagmar, additional, Moustafa, Tarek, additional, Hoefler, Gerald, additional, and Haemmerle, Guenter, additional

Published
2018
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50. Molecular tools in drug research — translational medicine

Author

Eder, Sandra and Wacheck, Volker

Subjects
yeast two hybrid, knock-out animal, Blotting, SAGE (serial analysis of gene expression), FACS, cloning, ACE2, sequencing, Article, Western/Northern, PCR, target validation, transfection, FISH, target identification, target deconvolution, Translational medicine, phage display, Cre/lox system, mass spectrometry
Abstract

2 The advent of high-throughput and increasingly sensitive research techniques in molecular biology in the last 20 years has altered fundamentally our understanding of molecular biology. The unraveling of the human genome has provided unprecedented insights into the molecular pathophysiology of diseases. DNA sequencing techniques allowed collecting huge amounts of genetic information, revealing genetic variation and variable expression of genes pinpointing to the molecular level of diseases. In parallel, analytical methods for evaluating large sets of proteins become available facilitating studies on the functional relevance of transient or stable expression of these molecules for a disease phenotype. These novel molecular techniques are nowadays at the heart of modern drug research as they allow identifying and validating novel molecular targets of disease, drug screening as well as the discovery of biomarkers for predicting and monitoring response to drug therapy.

Published
2011

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