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La artritis reumatoide (AR) es una enfermedad autoinmune caracterizada principalmente por dolor, inflamación, deformidad y destrucción persistente de las articulaciones afectadas. La AR suele estar asociada con sintomatología ansiosa debido a la falta de predictibilidad de los ataques de dolor y a las complicaciones de la enfermedad. El objetivo de este proyecto fue evaluar el efecto de la atención plena compasiva (APC) en la disminución de la percepción del dolor, sintomatología ansiosa y reactividad fisiológica ante estresores de pacientes con diagnóstico de AR, ya que previamente no se había investigado el efecto de la APC sobre estas variables en México. Participaron seis pacientes del hospital “Dr. Manuel Gea González” de la Ciudad de México, los cuales asistieron a una intervención de nueve sesiones con duración de dos horas cada una, a razón de una por semana. La intervención estuvo compuesta por psicoeducación, práctica y ejercicios para el hogar. Se implementó un diseño pretest-postest con muestreo a conveniencia. Los resultados mostraron una reducción significativa de la percepción del dolor, pero no de la sintomatología ansiosa. En las reacciones fisiológicas solo se obtuvieron cambios clínicos objetivos en algunas respuestas. La intervención con APC disminuye la percepción de dolor en pacientes con AR. Se sugiere un mayor número de participantes en futuros estudios, así como seguimientos a tres, seis y doce meses.

Preventive behavior and decision-making processes depend greatly on risk perception. Incorporating the affective component in risk assessment provides valuable information for understanding COVID-19-related risk. The study aimed to adapt and validate the COVID-19 Risk Belief Scale and evaluating Intuitive Risk Perception and its association with anxiety and worry. A cross-sectional study was conducted analyzing data from 694 Mexican adults, which was collected through on-line platforms during 2020. The final CFA including 18 items showed adequate goodness-of-fit indices (RMSEA = 0.059, 90% CI [0.053, 0.065]; CFI = 0.95; TLI = 0.94; SRMR = 0.044) supporting a five-factor structure. Moderate levels of intuitive risk perception were found, as well as moderate to low levels of worry and somatic anxiety. Significant correlations between both measures and risk perception were observed. This study confirms the importance of the affective component within risk assessment and findings become highly significant considering the current worldwide pandemic conditions.

Background The diagnosis of epilepsy is at times elusive for both neurologists and nonneurologists, resulting in delays in diagnosis and therapy. The development of screening methods has been identified as a priority in response to this diagnostic and therapeutic gap. EpiFinder is a novel clinical decision support tool designed to enhance the process of information gathering and integration of patient/proxy respondent data. It is designed specifically to take key terms from a patient's history and incorporate them into a heuristic algorithm that dynamically produces differential diagnoses of epilepsy syndromes. Objective The objective of this study was to test the usability and diagnostic accuracy of the clinical decision support application EpiFinder in an adult population. Methods Fifty-seven patients were prospectively identified upon admission to the Epilepsy Monitoring Unit (EMU) for episode classification from January through June of 2017. Based on semiologic input, the application generates a list of epilepsy syndromes. The EpiFinder-generated diagnosis for each subject was compared to the final diagnosis obtained via continuous video electroencephalogram (cVEEG) monitoring. Results Fifty-three patients had habitual events recorded during their EMU stay. A diagnosis of epilepsy was confirmed (with cVEEG monitoring) in 26 patients while 27 patients were found to have a diagnosis other than epilepsy. The algorithm appropriately predicted differentiation between the presence of an epilepsy syndrome and an alternative diagnosis with 86.8% (46/53 participants) accuracy. EpiFinder correctly identified the presence of epilepsy with a sensitivity of 86.4% (95% confidence interval [CI]: 65.0–97.1) and specificity of 85.1% (95% CI: 70.2–96.4). Conclusion The initial testing of the EpiFinder algorithm suggests possible utility in differentiating between an epilepsy syndrome and an alternative diagnosis in adult patients.

The aim of this study was to determine differences in executive function between “healthy” patients smokers and nonsmoker’s and also determine the differences in executive functions before and afte...

"Among the current interventions for generalized anxiety disorder (GAD), biofeedback-based training has shown efficacy at reducing physiological a rousal associated to the anxiety response. Traditonal protocols however generally include recordings of a small number of physiological responses. In addition, few studies have explored if biofeedback can impact on cognitive symptoms of GAD such as excessive worry . The purpose of this study was to determine the efficacy of a multiple-response biofeedback training protocol in reducing physiological a rousal of GAD and determine if these changes can impact on worry and co-occurring depressive symptoms. Fifteen GAD patients (9 women and 6 men) completed individual treatment comprising eleven biofeedback-assisted sessions. Psychophysiological recordings were taken and excessive worry, as well as anxiety and depressive symptoms were measured before and after training. Friedman ANOVA tests and objective clinical change showed positive effects by reducing levels of excessive worry as well as reporte d anxiety and depressive symptoms. Improvement also occurred on muscle tension and respiratory amplitude after treatment as supported by previous studies. No significant effects were observed in respiratory rate, heart rate , peripheral temperature or skin conductance. Findings of the present study support biofeedback-based interventions as an effective alternative for GAD and co-occurring depressive symptoms."

This paper estimates national methane emissions from solid waste disposal sites in Panama over the time period 1990-2020 using both the 2006 Intergovernmental Panel on Climate Change (IPCC) Waste Model spreadsheet and the default emissions estimate approach presented in the 1996 IPCC Good Practice Guidelines. The IPCC Waste Model has the ability to calculate emissions from a variety of solid waste disposal site types, taking into account country- or region-specific waste composition and climate information, and can be used with a limited amount of data. Countries with detailed data can also run the model with country-specific values. The paper discusses methane emissions from solid waste disposal; explains the differences between the two methodologies in terms of data needs, assumptions, and results; describes solid waste disposal circumstances in Panama; and presents the results of this analysis. It also demonstrates the Waste Model's ability to incorporate landfill gas recovery data and to make projections. The former default method methane emissions estimates are 25 Gg in 1994, and range from 23.1 Gg in 1990 to a projected 37.5 Gg in 2020. The Waste Model estimates are 26.7 Gg in 1994, ranging from 24.6 Gg in 1990 to 41.6 Gg in 2020. Emissions estimates for Panama produced by the new model were, on average, 8% higher than estimates produced by the former default methodology. The increased estimate can be attributed to the inclusion of all solid waste disposal in Panama (as opposed to only disposal in managed landfills), but the increase was offset somewhat by the different default factors and regional waste values between the 1996 and 2006 IPCC guidelines, and the use of the first-order decay model with a time delay for waste degradation in the IPCC Waste Model.

"El Trastorno de Ansiedad Generalizada (TAG) es uno de los cuadros de ansiedad con mayor prevalencia en el mundo. En México, su prevalencia a 12 meses es 0.4% en población general, equivalente a más de 400,000 personas. El cuadro incluye preocupación crónica, excesiva e incontrolable, nerviosismo, irritabilidad, tensión muscular y serio deterioro en la calidad de vida de quienes lo padecen. En este contexto es necesario determinar los factores que precipitan este trastorno a fin de desarrollar intervenciones eficaces para su prevención y tratamiento. Se ha documentado que la interacción familiar contribuye a la aparición del trastorno, pero aún falta explorar la especificidad del efecto de la interacción con cada padre, mejorar la operacionalización de las variables estudiadas y hacer comparaciones con grupos sanos, ya que se ha explorado sobre todo la sintomatología de los pacientes sin un diagnóstico confirmado. El objetivo del presente estudio fue explorar esta interacción con las tres precauciones metodológicas descritas mediante un esquema retrospectivo de casos y controles. Participantes 31 pacientes con diagnóstico confirmado de TAG y 31 participantes sin sintomatología. Los resultados revelaron que formas relativamente específicas de interacción familiar negativa se asocian con el posterior desarrollo de TAG en la edad adulta."