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4. Patients' preferences for subcutaneous trastuzumab versus conventional intravenous infusion for the adjuvant treatment of HER2-positive early breast cancer: final analysis of 488 patients in the international, randomized, two-cohort PrefHer study

Author

Fallowfield, Lesley, Jenkins, Valerie, Kilkerr, Justine, Langridge, Carolyn, Monson, Kathryn, Jakobsen, Erik Hugger, Nielsen, Mette Holck, Linnet, Soeren, Knoop, Ann, Pivot, Xavier, Bonnefoi, Herve, Mousseau, Mireille, Zelek, Laurent, Bourgeois, Hugues, Lefeuvre, Claudia Plesse, Bachelot, Thomas, Petit, Thierry, Brain, Etienne, Levy, Christelle, Gligorov, Joseph, Augustin, Doris, Graf, Heiko, Heinrich, Georg, Kroening, Hendrik, Kuemmel, Sherko, Müller, Volkmar, Overkamp, Friedrich, Park-Simon, Tjoung-Won, Schmidt, Marcus, Perlova-Griff, Lidia, Wolf, Christopher, Colleoni, Marco, Ballestrero, Alberto, Bernardo, Antonio, Ribecco, Angela Stefania, Gianni, Luca, Curigliano, Giuseppe, Brewczynska, Elżbieta, Jassem, Jacek, Shirinkin, Vadim, Manikhas, Alexey, Dvornichenko, Victoria, Lichinitser, Mikhail, Semiglazov, Vladimir, Mukhametshina, Guzel, Bulavina, Irina, Arranz, Enrique Espinosa, Ocon, Francisco Carabantes, Vivanco, Guillermo López, Bofill, Javier Salvador, Quintela, Ignacio Porras, Muñoz, Alfonso Sanchez, Pérez, Yolanda Fernández, Espinosa, Javier Cassinello, Alvarez, José Valero, del Prado, Rodrigo Lastra, De Merino, LuisLa Cruz, García, José Manuel Pérez, Frances, Santos Enrech, Edlund, Per, Norberg, Bengt, Wennstig, Anna-Karin, Lind, Pehr, Hauser, Nik, Tausch, Christoph, Camci, Celalettin, Arpaci, Fikret, Abali, Huseyin, Uslu, Ruchan, Tahir, Saad, Wheatley, Duncan, Chan, Stephen, Barrett-Lee, Peter, McAdam, Karen, Simcock, Richard, Burcombe, Russell, El-Maraghi, Robert, Califaretti, Nadia, Spadafora, Silvana, Sehdev, Sandeep, Sami, Amer, Verma, Sunil, Pivot, X., Gligorov, J., Müller, V., Curigliano, G., Knoop, A., Verma, S., Jenkins, V., Scotto, N., Osborne, S., and Fallowfield, L.

Published
2014
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9. Patientsʼ preferences for subcutaneous trastuzumab versus conventional intravenous infusion for the adjuvant treatment of HER2-positive early breast cancer: final analysis of 488 patients in the international, randomized, two-cohort PrefHer study

Author

Pivot, X., Gligorov, J., Müller, V., Curigliano, G., Knoop, A., Verma, S., Jenkins, V., Scotto, N., Osborne, S., Fallowfield, L., Fallowfield, Lesley, Jenkins, Valerie, Kilkerr, Justine, Langridge, Carolyn, Monson, Kathryn, Jakobsen, Erik Hugger, Nielsen, Mette Holck, Linnet, Soeren, Knoop, Ann, Pivot, Xavier, Bonnefoi, Herve, Mousseau, Mireille, Zelek, Laurent, Bourgeois, Hugues, Lefeuvre, Claudia Plesse, Bachelot, Thomas, Petit, Thierry, Brain, Etienne, Levy, Christelle, Gligorov, Joseph, Augustin, Doris, Graf, Heiko, Heinrich, Georg, Kroening, Hendrik, Kuemmel, Sherko, Müller, Volkmar, Overkamp, Friedrich, Park-Simon, Tjoung-Won, Schmidt, Marcus, Perlova-Griff, Lidia, Wolf, Christopher, Colleoni, Marco, Ballestrero, Alberto, Bernardo, Antonio, Ribecco, Angela Stefania, Gianni, Luca, Curigliano, Giuseppe, Brewczynska, Elżbieta, Jassem, Jacek, Shirinkin, Vadim, Manikhas, Alexey, Dvornichenko, Victoria, Lichinitser, Mikhail, Semiglazov, Vladimir, Mukhametshina, Guzel, Bulavina, Irina, Arranz, Enrique Espinosa, Ocon, Francisco Carabantes, Vivanco, Guillermo López, Bofill, Javier Salvador, Quintela, Ignacio Porras, Muñoz, Alfonso Sanchez, Pérez, Yolanda Fernández, Espinosa, Javier Cassinello, Alvarez, José Valero, del Prado, Rodrigo Lastra, Merino, Luis De La Cruz, García, José Manuel Pérez, Frances, Santos Enrech, Edlund, Per, Norberg, Bengt, Wennstig, Anna-Karin, Lind, Pehr, Hauser, Nik, Tausch, Christoph, Camci, Celalettin, Arpaci, Fikret, Abali, Huseyin, Uslu, Ruchan, Tahir, Saad, Wheatley, Duncan, Chan, Stephen, Barrett-Lee, Peter, McAdam, Karen, Simcock, Richard, Burcombe, Russell, El-Maraghi, Robert, Califaretti, Nadia, Spadafora, Silvana, Sehdev, Sandeep, Sami, Amer, and Verma, Sunil

Published
2014
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10. Determination of dissociation constants for protein-ligand complexes by electrospray ionization mass spectrometry

Author

Tjernberg, Agneta, Carno, Sofi, Oliv, Frida, Benkestock, Kurt, Edlund, Per-Olof, Griffiths, William J., and Hallen, Dan

Subjects
Proteins -- Research, Chemistry
Abstract

A fully automated biophysical assay based on electrospray ionization mass spectrometry (ESI-MS) for the determination of the dissociation constants ([K.sub.D]) between soluble proteins and low molecular mass ligands is presented. The method can be applied to systems where the relative MS response of the protein and the protein--ligand complexes do not reflect relative concentrations. Thus, the employed approach enables the use of both electrostatically and nonpolar bound complexes. The dynamic range is wider than for most biological assays, which facilitates the process of establishing a structure--activity relationship. This fully automated ESI-MS assay is now routinely used for ligand screening. The entire procedure is described in detail using hGHbp, a 25-kDa extracellular soluble domain of the human growth hormone receptor, as a model protein.

Published
2004

12. Screening of biomarkers in rat urine using LC/ electrospray ionization-MS and two-way data analysis

Author

Idborg-Bjorkman, Helena, Edlund, Per-Olof, Kvalheim, Olav M., Schuppe-Koistinen, Ina, and Jacobsson, Sven P.

Subjects
Rats as laboratory animals -- Research, Biological markers -- Research, Chemistry
Abstract

Biofluids, like urine, form very complex matrixes containing a large number of potential biomarkers, that is, changes of endogenous metabolites in response to xenobiotic exposure. This paper describes a fast and sensitive method of screening biomarkers in rat urine. Biomarkers for phospholipidosis, induced by an antidepressant drug, were studied. Urine samples from rats exposed to citalopram were analyzed using solid-phase extraction (SPE) and liquid chromatography mass spectrometry (LC/MS) analysis detecting negative ions. A fast iterative method, called Gentle, was used for the automatic curve resolution, and metabolic fingerprints were obtained. After peak alignment principal component analysis (PCA) was performed for pattern recognition, PCA loadings were studied as a means of discovering potential biomarkers. In this study a number of potential biomarkers of phospholipidosis in rats are discussed. They are reported by their retention time and base peak, as their identification is not within the scope of the study. In addition to the fact that it was possible to differentiate control samples from dosed samples, the data were very easy to interpret, and signals from xenobiotic-related substances were easily removed without affecting the endogenous compounds. The proposed method is a complement or an alternative to NMR for metabolomic applications.

Published
2003

14. Leukocyte nadir as a predictive factor for efficacy of adjuvant chemotherapy in breast cancer. Results from the prospective trial SBG 2000–1

Author

Poikonen-Saksela, Paula, primary, Lindman, Henrik, additional, Sverrisdottir, Asgerdur, additional, Edlund, Per, additional, Villman, Kenneth, additional, Tennvall Nittby, Lena, additional, Cold, Søren, additional, Bechmann, Troels, additional, Stenbygaard, Lars, additional, Ejlertsen, Bent, additional, Andersson, Michael, additional, Blomqvist, Carl, additional, Bergh, Jonas, additional, and Ahlgren, Johan, additional

Published
2020
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18. Disposition eller röd tråd? : En praktiknära studie av svensklärares bruk av ämnesspecifik terminologi

Author

Edlund, Per

Subjects
Studier av enskilda språk, terminologi, ämnesdidaktik, svenska, svensklärare, gymnasieelever, klassifikation, Specific Languages
Abstract

Ett mått på hur väl ett skolämne definierar sig i förhållande till de övriga är klassifikation. Den ämnesdidaktiska forskningen tyder på att svenskämnet, bland annat genom en låg tillämpning av ämnesspecifik terminologi, kännetecknas av en svag klassifikation. Tre svensklärare vid gymnasiet intervjuades angående deras uppfattning om sitt eget ämnes­relaterade språkbruk och observerades vid två lektionstillfällen var. Resultaten ger vid handen ett språkbruk som till största del präglas av termer som är ämnesrelaterade men inte hämtade från språk- eller litteraturvetenskapen. Detta indikerar en klassifikation av varken alltigenom svag eller stark grad. De uppfattningar som lärarna ger uttryck för i intervjuerna motsvaras endast delvis av den observerade undervisningen.

Published
2019

20. MPSA abstracts

Author

Aminlari, Mahmoud, Asquith, Thomas, Sarlo, Katherine, Bailey, Jerome M., Tu, Oanh, Issai, Gilbert, Ha, Alice, Shively, John E., Bell, Alexander W., Baur, Nicole C., Bergeron, John J. M., Ou, Wei -Jia, Thomas, David Y., Cianflone, Katherine, Baldo, Allain, Hincke, Maxwell T., Momparler, Richard L., Laliberté, Josée, Thomson, David M. P., Sutherland, M., Besada, Vladimir, Gonzalez, Javier, Padron, Gabriel, Garay, Hilda, Reyes, Osvaldo, Takao, Toshifumi, Shimonishi, Yasutsugu, Bischoff, Rainer, Roecklin, Dominique, Bouchon, Bernadette, Klarskov, Klaus, Van Dorsselaer, Alain, Brake, Patricia G., Pacitti, Anne, Higgins, Terry, Stevis, Panos, Malinowski, John, McElhiney, Sue, Huang, Janes, Vestal, Christine, Buckel, Scott D., Stevenson, Tracy, Loo, Joseph A., Caffrey, Martin, Wang, Jin, Wallace, Carmichael J. A., Clark-Lewis, Ian, Carraway, C. A. Carothers, Huang, J., Li, Y., Juang, S. -H., Gallo, A., Mayer, B. J., Carraway, K. L., Coleman, Patrick L., Sarpong, Daniel, Deerfield, II, David W., Holland-Minkley, Amanda, Hempel, John D., Nicholas, Jr., Hugh B., Denslow, Nancy D., Folmar, Leroy C., Sullivan, Craig V., Dixon, James D., Mark, Jonathan P., Elicone, Christopher P., Maleknia, Simin D., McGuinness, Brian F., Regnier, Fred E., Afeyan, Noubar B., Dolence, Julia M., Poulter, C. Dale, Egorov, Tsezi, Musolyamov, Alexander, Popineau, Yves, Andersen, Jens, Roepstorff, Peter, Falkenstein, Roberto J., Biscoglio de Jiménez Bonino, Mirtha J., Peña, Clara, Gauggel, D. L., Asquith, T. N., Isfort, R. J., Miller, N. S., Cody, D. B., Giblin, Michael F., Wong, Tuck C., Quinn, Thomas P., Grant, Gregory A., Crankshaw, Mark W., Griffith, Scott, Schroeder, Steve, Quinn, Thomas, Guinet, F., Petillot, Y., Chapsal, J. M., Dubayle, J., Greco, F., Barge, O., Forest, E., Valentin, C., Hahn, Frederick M, Baker, Jonathan A., Poulter, C. Dale, Haniu, Mitsuru, Kenney, William C., Rohde, Michael F., Harman, James G., Lee, Eun Ju, Glasgow, Joel, Lew, Sew Fen, Belduz, Ali O., Harris, Reed J., Molony, Michael S., Keyt, Lene H., Wu, Shiaw -Lin, Hawke, David H., Tso, Jaqueline, Early, Sherrell, Miller, Chad G., Hayman, G. Thomas, Miernyk, Jan A., Hellman, Ulf, Wernstedt, Christer, Góñez, Jorge, Hess, Daniel, Studer, Ralph, Hunziker, Peter E., Hirano, Hisashi, Watanabe, Yoshihiro, Barbashov, Sergei F., Komatsu, Setsuko, Hemmings, Andrew M., Miyagi, Masaru, Tsunasawa, Susumu, Huber, Reuben E., Roth, Nathan J., Gaunt, Michael T., Jenö, Paul, Mini, Thierry, Moes, Suzette, Horst, Martin, Jinnai, Kenji, Ashizawa, Tetsuo, Atassi, M. Zouhair, Johnsen, Anders H., Jensen, Hanne, Rehfeld, Jens F., Kamo, Masaharu, Kawakami, Takao, Miyatake, Norifumi, Tsugita, Akira, Keen, JN, Zagalsky, PF, Findlay, JBC, Kraft, Regine, Kostka, Susanne, Hartmann, Enno, Krutzsch, Henry C., Inman, John K., Machalinski, Claudia, Bonino, Mirtha Biscoglio de Jiménez, McRorie, Donald K., Dieckmann, Gregg R., Heilman, Susan, DeGrado, William F., Pecoraro, Vincent L., Kenny, James, Sahakian, Julie, Tso, Jacqueline, Moyer, Mary B., Burkhart, William A., Muranova, Tatyana, Makova, Lubov, Nicholas, Hugh, Hempel, John, Hinich, Amy, Deerfield, David, Behrmann, Joseph, Ropelewski, Alex, Nixon, Lori, Maneri, Leonard, Nugent, Kerry, Stoney, Ken, Wieser, John, Ohguro, Hiroshi, Palczewski, Krzysztof, Walsh, Kenneth A., Johnson, Richard S., Packman, Leonard C, Webster, Carl, Gray, John, Padrón, G., Morera, V., González, L. J., Támbara, Y., Besada, V., Villalonga, R., Chinea, G., Reyes, O., Bringas, H. Garay R., Nazábal, C., Parkinson, Bruce P., Yamada, Kent A., Randolph, Anne, Pisano, Anthony, Packer, Nicole H., Redmond, John W., Williams, Keith L., Gooley, Andrew A., Rasmussen, Hanne H., Mørtz, Ejvind, Mann, Matthias, Celis, Julio E., Rasmussen, Lone K., Sørensen, Esben S., Petersen, Torben E., Gliemann, Jørgen, Jensen, Poul Henning, Renlund, Staffan, Wadensten, Henrik, Persson, Annika, Persson, Per, Johansson, Agneta, Edlund, Per -Olof, Rose, Donald J., Sack, Ragna, Apffel, Alex, Miller, Chad, Levine, Rodney L., Sakaguchi, Kazuyasu, Zambrano, Nicola, Lewis, Marc S., Baldwin, Eric T., Shapiro, Bruce A., Erickson, John W, Omichinski, James G., Clore, G. Marius, Gronenborn, Angela M., Appella, Ettore, Schröder, Werner, Moser, Irmgard, Pansegrau, Werner, Lanka, Erich, Simpson, Richard J., Eddes, James, Ji, Hong, Reid, Gavin E., Moritz, Robert L., Højrup, Peter, Speicher, David W., Reim, David F., Speicher, Kaye D., Srinivasa, B. R., Barde, S. P., Stirtan, William G., Sukhanova, Alyona, Vorob'ev, Sergey, Gabibov, Alexander, Bronstein, Igor, Tanaka, Kenji, Einaga, Kuniko, Tsukada, Minoru, Tait, Jonathan F., Fujikawa, Kazuo, Takamoto, Keiji, Satake, Kazuo, Vakser, Ilya A., Velikodvorskaia, V. V., Gabibov, A. G., Rabinkov, A. G., Videler, Tennie, Osborne, Michael, Moore, Geoffrey, James, Richard, Kleanthous, Colin, Walent, Jane H., Bessen, Richard, Marsh, Dick, Clore, G. Marius, Niece, Ronald L., Tsao, Francis H. C., Wang, Hong, Weinberger, Scot R., Chakel, Lynn M., Wondrak, Ewald M., Kimmel, Alan R., and Louis, John M.

Published
1994
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22. Cisplatin, transplatin, and their hydrated complexes: separation and identification using porous graphitic carbon and electrospray ionization mass spectrometry

Author

Ehrsson, Hans C., Wallin, Inger B., Andersson, Anita S., and Edlund, Per Olof

Subjects
Cisplatin -- Research, Mass spectrometry -- Usage, Sequestration (Chemistry) -- Research, Liquid chromatography -- Methods, Chemistry
Abstract

A new liquid chromatographic technique for the separation of the anticancer drug cisplatin, its trans isomer, and their corresponding cytotoxic hydrated complexes is presented. The separation is performed on porous graphitic carbon using an alkaline aqueous phase, where the hydrated complexes are present in their less reactive, uncharged form. The electrospray mass spectrum of cisplatin differed from that of transplatin, giving a sodiated adduct ion. The monohydrated complex of cisplatin showed [[M - [H.sub.2]O].sup.+], [M.sup.+], and [[M - [H.sub.2]O + MeCN].sup.+] clusters starting at m/z 263, 281, and 304, respectively, using a solvent mixture containing acetonitrile. The identity of m/z 304 was established by MS/MS.

Published
1995

23. Fixed versus time-varying transfer functions for modelling business cycles

Author

Edlund, Per-olov and Sogaard, Henning T.

Subjects
Transfer functions -- Analysis, Business cycles -- Forecasts and trends, Recursive functions -- Analysis, Business, Economics, Government, Mathematics
Abstract

Thetraditional transfer function approach is compared to a recursive estimation procedure that allows the model to change over time in order to pinpoint and estimate transfer functions models relating leading indicators to the Swedish index of industrial production. Results of the comparison show that the recursive method is useful. It was also found that estimates of the model parameters indeed change over time.

Published
1993

27. Electric Propulsion for High Performance Ultralight Aircraft

Author

Edlund, Per and Mami, Nihel

Subjects
Electric, Black wing, Range of aircraft, Aircraft, Fossil conversion, Aircraft propulsion, Aerospace Engineering, Aeroplane propulsion, Propulsion, Battery performance, Environmental Flight, Range of aeroplane, Rymd- och flygteknik, Electical driveline, Blackwing, Petrol conversion
Abstract

Företaget BlackWing Sweden AB tillverkar ultralätta flygplan av kolfiberkomposit. Företaget vision är att tillverka ett flygplan som helt kan drivas av elektricitet med samma prestanda som flygplan drivet av fossila bränslen. För att kunna driva BlackWing flygplanet med hjälp av elektricitet behövs ett batteripaket, elektronikstyrning samt en elmotor. Därför har detta examensarbete ägnats åt att främst undersöka vilka elmotorer och battericeller som är mest lämpade för BlackWing flygplanet. Därefter togs resultatet fram genom beräkningar på battericeller och motorpaket med hjälp av insamlad information om motor-och batteriprestanda. För att få ett mer objektivt och systematiskt resultat här även en Pugh-matris används för att på ett enkelt sätt avgöra den mest lämpliga battericellen. Resultatet av detta arbete visade sig att i dagsläget är batteriet Envia, High Energi Pouch cell (ENV35011-CRC) och Siemens motor DYNADYN® 85 är mest lämpliga för BlackWing flygplanet. BlackWing Sweden AB manufactures ultralight aircraft made from carbon fibre composite. The company's vision is to produce an aircraft that can be completely powered by electricity with the same performance as the aircraft powered by fossil fuels. To operate the BlackWing aircraft using electricity it will need a battery pack, electronic controls and an electric driveline. Therefore, this thesis has been devoted primarily to study which electric engine and battery cells that would be most suitable for the BlackWing aircraft. The result was produced by calculations of the battery cells and electric driveline by using collected information about driveline and battery performance. To get a more objective and systematic results, a Pugh matrix was used to easily determine the most suitable battery cell. The results of this work showed that in the current situation, the battery Envia High Energy Drone Cell Pouch (ENV35011-CRC) and Siemens engine DYNADYN® 85 are the most suitable for the BlackWing aircraft.

Published
2017

28. How benzodiazepines are used to treat prehospital seizures

Author

Edlund, Per and Kruse, Richard

Subjects
Ambulans, ambulanssjuksköterska, prehospital sjukvård, Omvårdnad, prehospital care management, Nursing, benzodiazepines, bensodiazepiner, Ambulance, kramper, seizures
Abstract

Bakgrund: Akuta krampanfall drabbar många människor, både nationellt och internationellt. Detta behandlas i första hand med Bensodiazepiner, såsom Diazepam och Midazolam. Sveriges prehospitala behandlingsriktlinjer skiljer sig åt vid behandling av akuta krampanfall. Region Halland förnyade behandlingsriktlinjerna år 2011 och införde intranasal administrering av Midazolam Syfte: Att sammanställa behandlingsriktlinjerna angående medicinsk behandling vid kramper prehospitalt i Sverige samt kartlägga användandet av bensodiazepiner vid kramper prehospitalt i Region Halland. Metod: En kvantitativ registerstudie med en retrospektiv design användes. En sammanställning av Sveriges prehospitala behandlingsriktlinjer för medicinsk behandling av kramper utfördes. Chi-Två samt Fishers exakta test användes vid analysen av den insamlade datan från 127 ambulansjournaler i Region Halland. Resultat: Sammanställningen av Sveriges prehospitala behandlingsriktlinjer vid kramper visade att behandlingsriktlinjerna skiljer sig åt nationellt. Resultatet från kartläggningen av användandet med bensodiazepiner vid kramper prehospitalt i Region Halland visade att Diazepam var det vanligast använda läkemedlet samt att det fanns en signifikant skillnad i behandlingen med Diazepam rektalt relaterat till patientens ålder. Flertalet patienter som hade behandlats med Midazolam intranasalt behövde kompletterande behandling med Diazepam intravenöst. Slutsats: Behandlingsriktlinjerna för kramper prehospitalt skiljer sig åt nationellt. Diazepam var det vanligast använda läkemedlet samt en bristfällig följsamhet till behandlingsriktlinjerna framkom i Region Halland. Mer forskning behövs avseende ambulanssjuksköterskors erfarenheter av att behandla pågående kramper prehospitalt för ge patienterna möjlighet till en god omvårdnad på ett säkert sätt. Background: Acute seizures affects a large number of people both nationally and internationally. Seizures are primarily treated with benzodiazepines, such as Diazepam and Midazolam. Sweden's prehospital treatment guidelines differ in the treatment of acute seizures. Region Halland renewed the treatment guidelines in 2011 and introduced intranasal administration of Midazolam. Objective: To compile the treatment guidelines for medical treatment in prehospital seizures in Sweden and to survey the use of benzodiazepines in prehospital seizures in Region Halland. Method: A quantitative register study with a retrospective design was used. A compilation of Sweden's prehospital treatment guidelines was performed. Chi-Two and Fishers exact test are used in the analysis of the collected data from 127 ambulance journals in Region Halland. Results: The compilation of Swedish prehospital treatment guidelines for seizures showed that the treatment guidelines differ nationally. The survey of the use of benzodiazepines in prehospital seizures in Region Halland showed that Diazepam was the most commonly used drug, and that there was a significant difference in treatment with Diazepam rectally related to the age of the patient. Most patients treated with Midazolam intranasally needed additional therapy with Diazepam intravenously. Conclusion: The prehospital treatment guidelines for seizures differs nationally. Diazepam was the most commonly used drug and the compliance with the treatment guidelines is inadequate in Region Halland. More research is needed regarding from the ambulance nurse's experiences of treating ongoing prehospital seizures in order to provide patients with proper care in a safe way.

Published
2017

29. Chemotherapy versus chemoradiotherapy after surgery and preoperative chemotherapy for resectable gastric cancer (CRITICS): an international, open-label, randomised phase 3 trial

Author

Cats, Annemieke, primary, Jansen, Edwin P M, additional, van Grieken, Nicole C T, additional, Sikorska, Karolina, additional, Lind, Pehr, additional, Nordsmark, Marianne, additional, Meershoek-Klein Kranenbarg, Elma, additional, Boot, Henk, additional, Trip, Anouk K, additional, Swellengrebel, H A Maurits, additional, van Laarhoven, Hanneke W M, additional, Putter, Hein, additional, van Sandick, Johanna W, additional, van Berge Henegouwen, Mark I, additional, Hartgrink, Henk H, additional, van Tinteren, Harm, additional, van de Velde, Cornelis J H, additional, Verheij, Marcel, additional, Van Coevorden, Frits, additional, Vanhoutvin, Steven, additional, Hulshof, Maarten CCM, additional, Loosveld, Olaf JL, additional, Ten Tije, A (Bert) Jan, additional, Erdkamp, Frans LG, additional, Warmerdam, Fabienne ARM, additional, Van der Peet, Donald L, additional, Verheul, Henk MW, additional, Boerma, Djamila, additional, Los, Maartje, additional, Slot, Annerie, additional, Houtsma, Danny, additional, Portielje, Johanna EA, additional, Blaisse, Reinoud JB, additional, Spillenaar Bilgen, Ernst Jan, additional, Polée, Marco B, additional, Geenen, Maud M, additional, Braak, Jeffrey PBM, additional, Neelis, Karen J, additional, Slingerland, Marije, additional, Jansen, Rob LH, additional, Buijsen, Jeroen, additional, Beeker, Aart, additional, Eijsbouts, Quirijn AJ, additional, Van Riel, Johanna MGH, additional, Rozema, Tom, additional, Van Spronsen, Dick Johan, additional, Meerum Terwogt, Jetske M, additional, Tanis, Bea C, additional, Van der Torren-Conze, Adelheid ME, additional, Van Hilligersberg, Richard, additional, Koopman, Miriam, additional, Den Boer, Marien O, additional, Creemers, Geert-Jan, additional, Van der Sangen, Maurice, additional, Rentinck, Marjolein EM, additional, Van den Berg, H Pieter, additional, Jonkers, Ge JPM, additional, Grootenboers, Diane, additional, Vulink, Annelie JE, additional, Hovenga, Sjoerd, additional, Van der Mijle, Huub CJ, additional, Baars, Arnold, additional, Haringhuizen, Annebeth W, additional, Appels, Marije IE, additional, Rietbroek, Ron C, additional, Hendriksen, Ellen M, additional, Legdeur, Marie-Cecile JC, additional, Ten Bokkel Huinink, Daan, additional, Van Dobbenburgh, O Aart, additional, Smit, Jitty M, additional, Van Bochove, Aart, additional, Veldhuis, Gerrit-Jan, additional, Muller, Erik W, additional, Bonenkamp, J (Han) J, additional, Braam, Pètra M, additional, De Boer, Jaap, additional, Van Halteren, Henk K, additional, Valster, Fransje AA, additional, Imholz, Alex LT, additional, Van Dijk, Marjan A, additional, Van der Gaast, Ate, additional, Otten, J (Hans)-Martin MB, additional, Ceha, Heleen M, additional, Glimelius, Bengt, additional, Lagerbäck, Cecillia, additional, Perman, Mats, additional, Johnsson, Anders, additional, Borg, David, additional, Nielsen, Niels H, additional, Piwowar, Andrzej, additional, Elmlund, Mattias, additional, Hörberg, Helene, additional, Edlund, Per, additional, Johansson, Bengt, additional, Flygare, Petra, additional, and Jespersen, Marie Louise, additional

Published
2018
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30. Long-term safety and survival outcomes from the Scandinavian Breast Group 2004-1 randomized phase II trial of tailored dose-dense adjuvant chemotherapy for early breast cancer

Author

Matikas, Alexios, primary, Margolin, Sara, additional, Hellström, Mats, additional, Johansson, Hemming, additional, Bengtsson, Nils-Olof, additional, Karlsson, Lena, additional, Edlund, Per, additional, Karlsson, Per, additional, Lidbrink, Elisabet, additional, Linderholm, Barbro, additional, Lindman, Henrik, additional, Malmstrom, Per, additional, Villman, Kenneth, additional, Foukakis, Theodoros, additional, and Bergh, Jonas, additional

Published
2017
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32. Long-term safety and survival outcomes from the Scandinavian Breast Group 2004–1 (SBG 2004-1) randomized trial of tailored dose adjuvant chemotherapy for early breast cancer.

Author

Matikas, Alexios, primary, Margolin, Sara, additional, Hellstrom, Mats, additional, Johansson, Hemming, additional, Bengtsson, Nils-Olof, additional, Carlsson, Lena, additional, Edlund, Per, additional, Karlsson, Per, additional, Lidbrink, Elisabet, additional, Linderholm, Barbro Kristina, additional, Lindman, Henrik, additional, Malmstrom, Per, additional, Villman, Kenneth Karl, additional, Foukakis, Theodoros, additional, and Bergh, Jonas C. S., additional

Published
2017
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33. Faktorer som påverkar sjuksköterskors triagearbete på akutmottagningar

Author

Edlund, Per and Eriksson, Joakim

Subjects
Faktorer, Omvårdnad, Akutmottagning, Nursing, Triage, Triagebedömning, Sjuksköterska
Abstract

Bakgrund: Triage används för att bedöma och prioritera patienter. Vanligast sker detta av sjuksköterskor på akutmottagningar. Sjuksköterskorna som arbetar med triage har en svår uppgift att se till att rätt hjälp kommer till rätt patient. Syfte: Syftet var att belysa faktorer som påverkar sjuksköterskors triagebedömning av patienter på akutmottagningar. Metod: En litteraturöversikt där 17 vetenskapliga artiklar inkluderades. Artikelsökning gjordes i databaserna Cinahl och PubMed. Materialet granskades, analyserades och sammanställdes till ett resultat. Resultat: I resultatet framkom arbetslaget, arbetsplatsen, arbetsbelastning och informationsinsamling som faktorer som påverkar sjuksköterskors arbetsmiljö under triagering. Erfarenhet och intuition, kunskap och utbildning, egenskaper i genomförandet samt tillit till den egna kompetensen framkom som faktorer som påverkar sjuksköterskors egenskaper under triagering. Diskussion: Ett antal faktorer påverkar sjuksköterskors arbete med triage. Ett gott samarbete var viktigt för att underlätta det dagliga arbetet, skapa en god gruppdynamik och ge förutsättningar för en patientsäker vård. Erfarenhet framkom som en viktig del i triagearbetet, men triagesystemen är uppbyggda så att detta inte ska bli en begräsning. Slutsats: Det finns många faktorer som påverkar sjuksköterskors triagebedömning. Med dagens höga personalomsättning och arbetsbelastning är det svårt för sjuksköterskor att få den erfarenhet som krävs inom triagering. Triagesystemet utvecklas fortfarande i hög grad och det finns behov av fortsatt forskning inom området.

Published
2014

35. Dose-tailoring of FEC adjuvant chemotherapy based on leukopenia is feasible and well tolerated. Toxicity and dose intensity in the Scandinavian Breast Group phase 3 adjuvant Trial SBG 2000-1

Author

Edlund, Per, primary, Ahlgren, Johan, additional, Bjerre, Karsten, additional, Andersson, Michael, additional, Bergh, Jonas, additional, Mouridsen, Henning, additional, Holmberg, Stig B., additional, Bengtsson, Nils-Olof, additional, Jakobsen, Erik, additional, Møller, Susanne, additional, Lindman, Henrik, additional, and Blomqvist, Carl, additional

Published
2011
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39. Isolation and characterization of a trisulfide variant of recombinant human growth hormone formed during expression in Escherichia coli

Author

ANDERSSON, CLAES, primary, EDLUND, PER OLOF, additional, GELLERFORS, PÄR, additional, HANSSON, YNGVE, additional, HOLMBERG, ERLAND, additional, HULT, CARINA, additional, JOHANSSON, STIG, additional, KÖRDEL, JOHAN, additional, LUNDIN, RONNY, additional, MENDEL-HARTVIG, IB, additional, NORÉN, BENGT, additional, WEHLER, THOMAS, additional, WIDMALM, GÖRAN, additional, and ÖHMAN, JOHAN, additional

Published
2009
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40. Bisphosphonate treatment in primary breast cancer: Results from a randomised comparison of oral pamidronate versus no pamidronate in patients with primary breast cancer

Author

Kristensen, Bent, primary, Ejlertsen, Bent, additional, Mouridsen, Henning T., additional, Jensen, Maj-Britt, additional, Andersen, Jørn, additional, Bjerregaard, Brita, additional, Cold, Søren, additional, Edlund, Per, additional, Ewertz, Marianne, additional, Kamby, Claus, additional, Lindman, Henrik, additional, Nordenskjöld, Bo, additional, and Bergh, Jonas, additional

Published
2008
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41. Improved outcome from substituting methotrexate with epirubicin: Results from a randomised comparison of CMF versus CEF in patients with primary breast cancer

Author

Ejlertsen, Bent, primary, Mouridsen, Henning T., additional, Jensen, Maj-Britt, additional, Andersen, Jørn, additional, Cold, Søren, additional, Edlund, Per, additional, Ewertz, Marianne, additional, Jensen, Brita B., additional, Kamby, Claus, additional, Nordenskjold, Bo, additional, and Bergh, Jonas, additional

Published
2007
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