1. Pre-eclampsia/Eclampsia
- Author
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José Carlos Peraçoli, Vera Therezinha Medeiros Borges, José Geraldo Lopes Ramos, Ricardo de Carvalho Cavalli, Sérgio Hofmeister de Almeida Martins Costa, Leandro Gustavo de Oliveira, Francisco Lazaro Pereira de Souza, Henri Augusto Korkes, Ione Rodrigues Brum, Maria Laura Costa do Nascimento, Mário Dias Corrêa Junior, Nelson Sass, Angélica Lemos Debs Diniz, and Edson Viera da Cunha Filho
- Subjects
gestation ,hypertensive disorders ,pre-eclampsia ,eclampsia ,Gynecology and obstetrics ,RG1-991 - Abstract
Abstract Pre-eclampsia is a multifactorial and multisystemic disease specific to gestation. It is classically diagnosed by the presence of hypertension associated with proteinuria manifested in a previously normotensive pregnant woman after the 20th week of gestation. Pre-eclampsia is also considered in the absence of proteinuria if there is target organ damage. The present review takes a general approach focused on aspects of practical interest in the clinical and obstetric care of these women. Thus, it explores the still unknown etiology, current aspects of pathophysiology and of the diagnosis, the approach to disease prediction, its adverse outcomes and prevention. Management is based on general principles, on nonpharmacological and on pharmacological clinical treatment of severe or nonsevere situations with emphasis on the hypertensive crisis and eclampsia. Obstetric management is based on preeclampsia without or with signs of clinical and/or laboratory deterioration, stratification of gestational age
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