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Abstract: A previous study developed and validated a multi-item instrument for the assessment of violent ideations, the “Violent Ideations Scale” (VIS). However, the final 12-item scale contained no items relating to sexual violence and was thus lacking an important dimension of violence. The current study explores an expansion of the original VIS to include ideations of sexual violence and investigates the psychometric properties of this new version: The Violent Ideations Scale-Extended (VIS-X). The VIS-X was completed by participants in the latest wave of the z-proso study ( N = 1,177; 595 females, 580 males aged 19–22 years). Exploratory factor analysis was conducted in a calibration sample and confirmatory factor analysis in a validation sample to establish a two subscale structure as optimal. Cronbach’s α and Composite Reliability suggested good internal consistency. Nomological analysis supported the convergent validity of the scores.

This study examined longitudinal links between several dimensions of parent–child relationship and adolescent substance use, and tested the role of self-control in mediating these. Data came from the Zurich Project on the Social Development from Childhood to Adulthood. Validated questionnaires were used to measure parent–child domains at age 11, self-control at age 13, and substance use at ages 13, 15, 17, and 20. Low positive parenting and parental supervision, as well as aversive parenting, correlated with substance use. Linear regression model revealed that aversive parenting, low child disclosure, low positive parenting, and low parental involvement at age 11 predicted substance use at different stages of adolescence. These associations were mediated by low self-control at age 13. Involving parents and increasing their knowledge about desirable parental practices and ways to help their children to develop adequate self-control could be an effective element in substance use prevention strategies.

The goal of the current analyses was to explore associations of self-rated physical attractiveness with facets of psychological well-being across adolescence. Participants provided information on their perceived physical attractiveness, internalized distress, suicidal ideation, and self-harm at 15, 17 and 20 years of age. Male adolescents repeatedly provided higher ratings of their own physical attractiveness in comparison to female peers. Self-perceived physical attractiveness was negatively associated with internalized distress in 15- to 20-year-old girls. In boys this association reached statistical significance only at the ages of 17 and 20 years. Statistically significant relations between suicidal ideation, self-harm and physical attractiveness resulted in girls only. Findings suggest small but stable relationships between self-rated physical attractiveness and facets of psychological well-being between 15 and 20 years–particularly in girls. Results underline the importance of self-perceived attractiveness in relation to mental health across adolescence.

Background: In many countries, there is limited consideration of the psychological wellbeing of women during antenatal and postnatal care. Among a range of contributing factors, one practical reason is that brief, valid and reliable screening tools are not widely used to guide clinical interviews. The present study evaluated psychometric properties of three brief scales that measure recent wellbeing (the WHO-5 index), perceived stress (the PSS-10) and depression (the PHQ-9). Methods: A prospective birth cohort study was completed in Hue City, central Vietnam with 148 pregnant women in the third trimester of pregnancy, with follow-up 3-5 months after childbirth. Moderate-to-severe antenatal depressive symptoms were used as the reference standard to validate the WHO-5 and PSS-10. Results: Approximately one-third of the women indicated significant stress and 12% reported moderate to severe depressive symptoms during pregnancy. The WHO-5 and PSS-10 had good internal consistency (Cronbach’s alpha=0.76–0.81) and good discriminant properties against prenatal depression. Area Under the Curve (AUC) values showed good predictive validity to detect postpartum depressive symptoms for the WHO-5 [AUC=0.73, 95% CI (0.60 - 0.86)] and the PSS-10 [AUC=0.69, 95% CI (0.45 – 0.92)]. WHO-5 scores ≤ 60/100 and PSS-10 scores ≥ 20/40 provided good sensitivity (approx.83%) and fair specificity (approx.61%) to detect depression pre- and post-natally. Conclusions: Given these satisfactory psychometric properties, brief but broad screening that includes questions about positive wellbeing and recent stress in addition to depressive symptoms should be integrated into routine psychosocial care for pregnant women in Vietnam and similar cultural contexts.

The efficacy of ustekinumab, an antagonist of the p40 subunit of interleukin-12 and interleukin-23, as induction and maintenance therapy in patients with ulcerative colitis is unknown.We evaluated ustekinumab as 8-week induction therapy and 44-week maintenance therapy in patients with moderate-to-severe ulcerative colitis. A total of 961 patients were randomly assigned to receive an intravenous induction dose of ustekinumab (either 130 mg [320 patients] or a weight-range-based dose that approximated 6 mg per kilogram of body weight [322]) or placebo (319). Patients who had a response to induction therapy 8 weeks after administration of intravenous ustekinumab were randomly assigned again to receive subcutaneous maintenance injections of 90 mg of ustekinumab (either every 12 weeks [172 patients] or every 8 weeks [176]) or placebo (175). The primary end point in the induction trial (week 8) and the maintenance trial (week 44) was clinical remission (defined as a total score of ≤2 on the Mayo scale [range, 0 to 12, with higher scores indicating more severe disease] and no subscore1 [range, 0 to 3] on any of the four Mayo scale components).The percentage of patients who had clinical remission at week 8 among patients who received intravenous ustekinumab at a dose of 130 mg (15.6%) or 6 mg per kilogram (15.5%) was significantly higher than that among patients who received placebo (5.3%) (P0.001 for both comparisons). Among patients who had a response to induction therapy with ustekinumab and underwent a second randomization, the percentage of patients who had clinical remission at week 44 was significantly higher among patients assigned to 90 mg of subcutaneous ustekinumab every 12 weeks (38.4%) or every 8 weeks (43.8%) than among those assigned to placebo (24.0%) (P = 0.002 and P0.001, respectively). The incidence of serious adverse events with ustekinumab was similar to that with placebo. Through 52 weeks of exposure, there were two deaths (one each from acute respiratory distress syndrome and hemorrhage from esophageal varices) and seven cases of cancer (one each of prostate, colon, renal papillary, and rectal cancer and three nonmelanoma skin cancers) among 825 patients who received ustekinumab and no deaths and one case of cancer (testicular cancer) among 319 patients who received placebo.Ustekinumab was more effective than placebo for inducing and maintaining remission in patients with moderate-to-severe ulcerative colitis. (Funded by Janssen Research and Development; UNIFI ClinicalTrials.gov number, NCT02407236.).

Violent ideations are increasingly recognized as an important psychological process involved in aggressive and violent behavior. However, little is known about the processes that contribute to violent ideations. This paper therefore examines the effects of dispositional and situational factors on violent ideations during late adolescence. More specifically, it examines the extent to which violent victimization triggers violent ideations. Furthermore, it examines whether effects of violent victimization on violent ideations differ by gender. This study uses data from two waves of the Zurich Project on the Social Development from Childhood into Adulthood (z-proso; n= 1,465). Full-information maximum likelihood regressions are used to regress violent ideations at age 17 on social and psychological characteristics measured at age 15 and reports of previous year violent victimization measured at age 17. The results show that violent ideations at age 17 are strongly influenced by violent thoughts, aggressive behavior, violent media consumption, moral neutralization of violence, and internalizing symptoms measured at age 15. Moreover, victimization experiences increase the likelihood of violent ideations over and above pre-existing dispositions and prior violent ideations. The effects are stronger for adolescent males than for females.

Background: Randomised controlled trials (RCTs) are used to evaluate social and psychological interventions and inform policy decisions about them. Accurate, complete, and transparent reports of social and psychological intervention RCTs are essential for understanding their design, conduct, results, and the implications of the findings. However, the reporting of RCTs of social and psychological interventions remains suboptimal. The CONSORT Statement has improved the reporting of RCTs in biomedicine. A similar high-quality guideline is needed for the behavioural and social sciences. Our objective was to develop an official extension of the Consolidated Standards of Reporting Trials 2010 Statement (CONSORT 2010) for reporting RCTs of social and psychological interventions: CONSORT-SPI 2018. Methods: We followed best practices in developing the reporting guideline extension. First, we conducted a systematic review of existing reporting guidelines. We then conducted an online Delphi process including 384 international participants. In March 2014, we held a 3-day consensus meeting of 31 experts to determine the content of a checklist specifically targeting social and psychological intervention RCTs. Experts discussed previous research and methodological issues of particular relevance to social and psychological intervention RCTs. They then voted on proposed modifications or extensions of items from CONSORT 2010. Results: The CONSORT-SPI 2018 checklist extends 9 of the 25 items from CONSORT 2010: background and objectives, trial design, participants, interventions, statistical methods, participant flow, baseline data, outcomes and estimation, and funding. In addition, participants added a new item related to stakeholder involvement, and they modified aspects of the flow diagram related to participant recruitment and retention. Conclusions: Authors should use CONSORT-SPI 2018 to improve reporting of their social and psychological intervention RCTs. Journals should revise editorial policies and procedures to require use of reporting guidelines by authors and peer reviewers to produce manuscripts that allow readers to appraise study quality, evaluate the applicability of findings to their contexts, and replicate effective interventions.

Weapon carrying has detrimental effects for perpetrators and victims alike. It is therefore imperative that research efforts are invested into establishing those contextual factors that are associated with this antisocial behavior. This systematic and meta-analytic review investigates the association of weapon carrying with bullying perpetration and victimization inside and outside the school context. Results on pure bullies, pure victims and bully-victims are also presented. Further to extensive searches, across 20 databases and 46 journals, and careful screening of reports, in line with pre-established methodological criteria, a total of 35 manuscripts are included in the meta-analysis. Narrative results based on longitudinal studies are also presented but not meta-analyzed given the variability in study characteristics and the small number of studies. Weapon carrying is significantly associated with both bullying perpetration (adjusted $\textit{OR}$ = 2.64; $\textit{p}$ < 0.001) and victimization (adjusted $\textit{OR}$ = 1.58; $\textit{p}$ < 0.05). Effect sizes are larger when looking at discrete categories of pure bullies (adjusted $\textit{OR}$ = 3.24; $\textit{p}$ < 0.01), pure victims (adjusted $\textit{OR}$ = 1.79; $\textit{p}$ < 0.05) and bully-victims (adjusted $\textit{OR}$ = 5.66; $\textit{p}$ < 0.001) when compared with non-involved school children. Subgroup analyses suggest that pure victims ($\textit{Q}$ = 6.77; $\textit{p}$ < 0.01) and bully-victims ($\textit{Q}$ = 8.01; $\textit{p}$ < 0.01) are significantly more likely to carry a weapon inside than outside the school, thus rendering support to the ‘vulnerability/self-protection’ hypothesis. Pure bullies have the same odds of carrying a weapon inside and outside the school context ($\textit{Q}$ = 0.60; $\textit{p}$ = 0.44), supporting a persistent antisocial personality theoretical framework. Implications for policy and practice arising from our results are discussed.