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Chronic hemodialysis (HD) patients are particularly vulnerable to coronavirus disease 2019 (COVID-19). We assessed the prevalence and psychosocial impact of COVID-19 in these patients in Senegal. This multicenter prospective, descriptive, and analytical study included 345 patients who had been on chronic HD for at least 1 month (average age = 49.67 ± 14.58 years; sex ratio: 1.14). Eighty-one patients (23.48%) believed that COVID-19 negatively impacted their dialysis treatment. In total, 257 patients (74.49%) perceived themselves to be at risk, and 128 patients (37.1%) were worried about attending the dialysis center. Only 109 patients (31.59%) were tested by polymerase chain reaction; 13 (11.92%) were positive. In total, 322 patients (93.6%) were informed through television or radio, 338 (97.97%) were aware of the barrier measures, and 83 (24.06%) had difficulty applying the barrier measures, mainly on transport. Masks were the best-known measure, as reported by 331 patients (95.94%). In a bivariate analysis, knowledge of the barrier measures was associated with education level (P

Secondary hyperparathyroidism (SHPT) is a common complication of end-stage renal disease. Surgical management occurs in severe forms and/or unresponsive medical treatment. The aim of this study was to outline the indications of parathyroidectomy and its evolution after surgical approach. It was a five-year multicenter backward study in Otorhinolaryngology Department of Fann Hospital and four dialysis centers in Dakar. We include all patients with SHPT who underwent surgery. Preoperative clinical and paraclinical parameters, clinical-biological evolution, and histology findings of the resected parathyroid specimen were collected. Out of 58 patients with hyperparathyroidism, 18 patients required parathyroidectomy, corresponding to a prevalence of 31%. Mean age of patients was 46.6 ± 15.29 years and sex ratio 0.61. Mean duration on dialysis was 44.4 ± 30 months. Ten patients (55.56%) had bone pain and nine patients (50%) had joint pain. Mean serum calcium was 97.27 ± 8.66 mg/L. Mean blood phosphorus levels were 40.47 ± 9.99 mg/L. Mean iPTH rate was 1493.22 ± 1014.93 ng/mL, with a maximum of 5000 ng/mL (77N). Mean value of 25-OH Vitamin D was 32.89 ± 16.02 ng/mL. Parathyroidectomy was indicated after failure of medical treatment with persistence of a serum intact parathyroid hormone concentration above 800 μg/mL in all patients. Subtotal parathyroidectomy (7/8) was performed in 11 patients (61.1%). Two patients (11.11%) benefited from a selective parathyroidectomy (3/4). Evolution was favorable for 13 patients, corresponding to a success rate of 72.2%. It was unfavorable in five patients including one patient with hypoparathyroidism and four patients with recurrent hyperparathyroidism. Surgery for patients with renal hyperparathyroidism in the era of calcimimetics continues to play an important role in selected patients and achieves efficient control of hyperparathyroidism in developing countries.

Few data from West Africa are available on the prevalence of the different kidney diseases. One hundred fifteen patients underwent renal biopsy in the nephrology department in Dakar from 1993 to 1998. Nephrotic syndrome was the main indication of biopsy (67%). The primary nephropathies were found in 69.5% of the patients, the secondary nephropathies in 23.5% and unclassified nephropathies in 7%. Of the primary nephropathies, focal segmental glomerulosclerosis was found in 47% of the patients followed by membranous glomerulopathy in 12.5%. Secondary nephropathies were dominated by lupus nephritis followed by tubulo-interstitial toxic nephritis, misnamed as "tropical nephropathy", due to the intake of local home remedies.