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2 results on '"El Sharkwy I"'

1. Performance Investigation of MOF-Ethanol Based Adsorption Cooling Cycle

Author

ALrsheedi, S., Saha, B. B., Chakraborty, A., Miyazaki, T., Thu, K., Jribi, S., El-Sharkwy, I., and Koyama, S.

Subjects
solar powered, adsorption, cooling cycle metal organic framework, ethanol
Abstract

Adsorption cooling systems employs benign refrigerants and could be driven by solar energy or waste heat. Therefore, they are a feasible alternative to vapor compression cooling systems. This paper investigates the performance of metal-organic framework (MOF) ethanol based adsorption cooling cycle. Adsorption isotherms of ethanol onto MOF of type MIL-101 -Cr have been measured experimentally using a magnetic suspension balance for temperatures ranging from 30 to 70 °C and within pressure up to 20 kPa. Then, the experimental data were fitted using Toth adsorption isotherms equation. The coefficient of performance (COP) and specific cooling effect (SCE) were then calculated for evaporation and cooling temperatures of 10 and 30 °C, respectively. The experimental results show that COP attains 0.70 and SCE increases with the increase of heat source temperature and attains 225 kJ per kg of adsorbent at temperature of 80 °C which makes this pair suitable for solar cooling application.

Published
2016

2. l-Carnitine plus metformin in clomiphene-resistant obese PCOS women, reproductive and metabolic effects: a randomized clinical trial.

Author

El Sharkwy I and Sharaf El-Din M

Subjects
Adult, Blood Glucose drug effects, Blood Glucose metabolism, Female, Fertility Agents, Female therapeutic use, Hormones metabolism, Humans, Infertility, Female complications, Infertility, Female metabolism, Infertility, Female physiopathology, Insulin Resistance physiology, Obesity complications, Obesity metabolism, Obesity physiopathology, Polycystic Ovary Syndrome complications, Polycystic Ovary Syndrome metabolism, Polycystic Ovary Syndrome physiopathology, Pregnancy, Pregnancy Rate, Reproduction drug effects, Treatment Outcome, Young Adult, Carnitine administration & dosage, Clomiphene therapeutic use, Drug Resistance drug effects, Infertility, Female drug therapy, Metformin administration & dosage, Obesity drug therapy, Polycystic Ovary Syndrome drug therapy
Abstract

To evaluate the reproductive and metabolic effects of L-carnitine plus metformin in clomiphene citrate (CC) resistant obese polycystic ovary syndrome (PCOS) women. A double-blinded randomized controlled clinical trial, clomiphene-citrate resistant obese women were allocated randomly to receive CC plus metformin and L-carnitine ( n  = 138) or CC plus metformin and placebo ( n  = 136). The primary outcome was clinical pregnancy rate. The secondary outcomes were hormonal and metabolic profile changes in addition to ovulation and first trimester (13 weeks) miscarriage rates. Clomiphene-citrate, L-carnitine, and metformin group showed significant improvement in the menstrual regularity, ovulation rate, and pregnancy rate compared to CC plus metformin and placebo group (29% vs. 9%, 34.7% vs. 11%, and 28.2% vs. 6.6%, respectively). No statistically significant difference in the miscarriage rate between the two groups ( p  = .08). After three months of treatment, the reduction in body mass index (BMI) was non-significant ( p  = .061) between both groups. The hormonal and metabolic parameters were more significantly improved in the L-carnitine group compared with the placebo group. l-Carnitine may act synergistically with metformin for improvement of reproductive performance, insulin resistance, and lipid profile in clomiphene-resistant obese PCOS women.

Published
2019
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