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151 results on '"Elbassiouny, Ahmed"'

1. Revisiting Africa’s Stroke Obstacles and Services (SOS)

Author

Roushdy, Tamer, Elbassiouny, Ahmed, Kesraoui, Selma, Temgoua, Michael, Nono, Kiatoko Ponte, Melkamu, Selam Kifelew, Sadiq, Eitzaz, Francis, Patty, Omar, Oday F., Peter, Waweru, Gopaul, Urvashy, Belahsen, Mohammed Faouzi, Ugbem, Lukpata Philip, Ben-Adji, Djibrilla, Woodcock, Noëmie, Mohamed, Muhyadin Hassan, Matuja, Sarah, Mhiri, Chokri, Saylor, Deanna, Maged, Mohamed, Shokri, Hossam, and Nahas, Nevine El

Published
2025
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2. TICA-CLOP STUDY: Ticagrelor Versus Clopidogrel in Acute Moderate and Moderate-to-Severe Ischemic Stroke, a Randomized Controlled Multi-Center Trial: Ticagrelor Versus Clopidogrel in Acute Moderate and Moderate-to-Severe Ischemic Stroke

Author

Ahmed, Sherihan Rezk, Nahas, Nevine El, Khalil, Mohamed Fouad Elsayed, Elbassiouny, Ahmed, Almoataz, Mohamed Ahmed, Omar, Tarek Youssif, Daabis, Ahmed Mohamed Ali, Refat, Hossam Mohamed, Ebied, Ahmed Ahmed Mohamed Kamal, Hassan, Asmaa Mohammed, Mohamed, Diaa Mostafa Atiaa, Ismaiel, Mohamed, and Zeinhom, Mohamed G.

Published
2025
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3. A multicenter trial on the predictors of different subtypes of hemorrhagic infarction after thrombolysis

Author

Zeinhom, Mohamed G., Ahmed, Sherihan Rezk, Kohail, Ahmed Mohamed, Kamel, Islam Fathallah Mohamed, Abdelrahman, ALshimaa Mahfouz, AL-Nozha, Omar M., Almoataz, Mohamed, Youssif, Tarek Youssif Omar, Daabis, Ahmed Mohamed Ali, Refat, Hossam Mohamed, Ebied, Ahmed Ahmed Mohamed Kamal, Elbassiouny, Ahmed, Akl, Ahmed Zaki Omar, Shuaib, Ashfaq, Ismaiel, Mohamed, Ibrahem, Asmaa Ibrahem Desouky Mostafa, and Khalil, Mohamed Fouad Elsayed

Published
2024
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7. Global Impact of COVID-19 on Stroke Care and IV Thrombolysis.

Author

Nogueira, Raul, Qureshi, Muhammad, Abdalkader, Mohamad, Martins, Sheila, Yamagami, Hiroshi, Qiu, Zhongming, Mansour, Ossama, Sathya, Anvitha, Czlonkowska, Anna, Tsivgoulis, Georgios, Aguiar de Sousa, Diana, Demeestere, Jelle, Mikulik, Robert, Vanacker, Peter, Siegler, James, Kõrv, Janika, Biller, Jose, Liang, Conrad, Sangha, Navdeep, Zha, Alicia, Czap, Alexandra, Holmstedt, Christine, Turan, Tanya, Ntaios, George, Malhotra, Konark, Tayal, Ashis, Loochtan, Aaron, Ranta, Annamarei, Mistry, Eva, Alexandrov, Anne, Huang, David, Yaghi, Shadi, Raz, Eytan, Sheth, Sunil, Mohammaden, Mahmoud, Frankel, Michael, Bila Lamou, Eric, Aref, Hany, Elbassiouny, Ahmed, Hassan, Farouk, Menecie, Tarek, Mustafa, Wessam, Shokri, Hossam, Roushdy, Tamer, Sarfo, Fred, Alabi, Tolulope, Arabambi, Babawale, Nwazor, Ernest, Sunmonu, Taofiki, Wahab, Kolawole, Yaria, Joseph, Mohammed, Haytham, Adebayo, Philip, Riahi, Anis, Sassi, Samia, Gwaunza, Lenon, Ngwende, Gift, Sahakyan, David, Rahman, Aminur, Ai, Zhibing, Bai, Fanghui, Duan, Zhenhui, Hao, Yonggang, Huang, Wenguo, Li, Guangwen, Li, Wei, Liu, Ganzhe, Luo, Jun, Shang, Xianjin, Sui, Yi, Tian, Ling, Wen, Hongbin, Wu, Bo, Yan, Yuying, Yuan, Zhengzhou, Zhang, Hao, Zhang, Jun, Zhao, Wenlong, Zi, Wenjie, Leung, Thomas, Chugh, Chandril, Huded, Vikram, Menon, Bindu, Pandian, Jeyaraj, Sylaja, P, Usman, Fritz, Farhoudi, Mehdi, Hokmabadi, Elyar, Horev, Anat, Reznik, Anna, Sivan Hoffmann, Rotem, Ohara, Nobuyuki, Sakai, Nobuyuki, Watanabe, Daisuke, Yamamoto, Ryoo, Doijiri, Ryosuke, Tokuda, Naoki, Yamada, Takehiro, Terasaki, Tadashi, and Yazawa, Yukako

Subjects
COVID-19, Cross-Sectional Studies, Hospitalization, Humans, Pandemics, Retrospective Studies, SARS-CoV-2, Stroke, Thrombolytic Therapy
Abstract

OBJECTIVE: To measure the global impact of COVID-19 pandemic on volumes of IV thrombolysis (IVT), IVT transfers, and stroke hospitalizations over 4 months at the height of the pandemic (March 1 to June 30, 2020) compared with 2 control 4-month periods. METHODS: We conducted a cross-sectional, observational, retrospective study across 6 continents, 70 countries, and 457 stroke centers. Diagnoses were identified by their ICD-10 codes or classifications in stroke databases. RESULTS: There were 91,373 stroke admissions in the 4 months immediately before compared to 80,894 admissions during the pandemic months, representing an 11.5% (95% confidence interval [CI] -11.7 to -11.3, p < 0.0001) decline. There were 13,334 IVT therapies in the 4 months preceding compared to 11,570 procedures during the pandemic, representing a 13.2% (95% CI -13.8 to -12.7, p < 0.0001) drop. Interfacility IVT transfers decreased from 1,337 to 1,178, or an 11.9% decrease (95% CI -13.7 to -10.3, p = 0.001). Recovery of stroke hospitalization volume (9.5%, 95% CI 9.2-9.8, p < 0.0001) was noted over the 2 later (May, June) vs the 2 earlier (March, April) pandemic months. There was a 1.48% stroke rate across 119,967 COVID-19 hospitalizations. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was noted in 3.3% (1,722/52,026) of all stroke admissions. CONCLUSIONS: The COVID-19 pandemic was associated with a global decline in the volume of stroke hospitalizations, IVT, and interfacility IVT transfers. Primary stroke centers and centers with higher COVID-19 inpatient volumes experienced steeper declines. Recovery of stroke hospitalization was noted in the later pandemic months.

Published
2021

10. Frequency, phenotypes, and neuroimaging of early post stroke movement disorders: a prospective study.

Author

Samra, Eslam, Roushdy, Tamer, Zaki, Amr S., Mansour, Alia H., Elbassiouny, Ahmed, and Shalash, Ali

Subjects
MOVEMENT disorders, LACUNAR stroke, STROKE, CEREBRAL infarction, MEDICAL sciences
Abstract

Copyright of Egyptian Journal of Neurology, Psychiatry & Neurosurgery is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2025
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11. Outcomes and safety of mechanical thrombectomy, alteplase, and conventional medical care in the treatment of acute M2 segment middle cerebral artery occlusion: a comparative study.

Author

Khedr, Eman M., Elbassiouny, Ahmed, Nageeb, Mahmoud, Aly, Ahmed, Mohamed, Khalid O., and Haridy, Nourelhoda A.

Subjects
*TISSUE plasminogen activator, *ISCHEMIC stroke, *THROMBECTOMY, *INTRACRANIAL hemorrhage, *ACUTE medical care
Abstract

Background: Data on mechanical thrombectomy (MT) to treat M2 occlusions of the middle cerebral artery (MCA) are sparse. We report the outcome and safety of MT versus intravenous recombinant tissue plasminogen activator (IV rTPA) versus conventional medical treatment (CMT) of acute ischemic stroke (AIS) due to occlusion of the M2 segment of the MCA. This prospective longitudinal intervention study compared the outcomes and safety of MT, rTPA, and CMT in M2 occlusion AIS patients. National Institutes of Health Stroke Scale (NIHSS), modified Rankin scale (mRS), and recanalization rate assessed outcomes. Results: 74 AIS patients were recruited (23 MT, 23 rTPA, 28CMT). MT group had significantly higher admission NIHSS (p = 0.018) and mRS (p = 0.023) than rTPA. At 24 h, NIHSS improved more with MT and rTPA than CMT (p < 0.0001). At 3 months, mRS were better with MT and rTPA versus CMT (p < 0.0001). Successful recanalization occurred in 73.9% of the MT group. 69% of the MT group required stent retrieval plus aspiration thrombectomy, and 60.9% required ≥ 3 trials, but outcomes did not differ by technique or number of trials. A good outcome (mRS 0–2) at 3 months was achieved in 69.6% MT versus 65.2% rTPA versus 7.1% CMT (p < 0.0001). Symptomatic intracranial hemorrhage (sICH) rates were slightly, but insignificantly, higher with CMT. Mortality did not significantly differ between groups. Conclusions: For M2 occlusions, MT and rTPA achieved better early and 3-month outcomes than CMT; however, MT was not superior to rTPA. MT of M2 is feasible and effective, with a lower hemorrhage rate than rTPA and CMT. Trial registration: This study was prospectively registered in the clinical trial with ClinicalTrials.gov ID (NCT05091320). The link: https://clinicaltrials.gov/study/NCT05091320 [ABSTRACT FROM AUTHOR]

Published
2025
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16. In Memoriam of Professor Hany Aref: The Father, the Leader, and the Mentor

Author

El Nahas, Nevine, primary, El-Khawas, Hala, additional, Elbassiouny, Ahmed, additional, Shokri, Hossam, additional, Hamid, Eman, additional, Fathy, Mai, additional, Abushady, Eman, additional, Kenawy, Fatma, additional, Dawood, Noha, additional, Zaki, Amr, additional, Bedros, Rady Y., additional, and Roushdy, Tamer, additional

Published
2023
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19. Stroke services in MENA: What is there and what is needed

Author

Aref, Hany, primary, El Nahas, Nevine, additional, Alrukn, Suhail Abdulla, additional, Khan, Maria, additional, Kesraoui, Selma, additional, Alnidawi, Firas, additional, Hokmabadi, Elyar Sadeghi, additional, Farhoudi, Mehdi, additional, Fairooz, Muataz, additional, Batayha, Waleed, additional, Salmeen, Athari, additional, Abdulrahman, Husen, additional, Belahsen, Mohammed Faouzi, additional, Al Hashmi, Amal M., additional, Akhtar, Naveed, additional, Al-Johani, Mohammed, additional, Seidi, Osheik Abu’Asha, additional, Jouhar, Anas, additional, Mhiri, Chokri, additional, Elbassiouny, Ahmed, additional, Shokri, Hossam, additional, and Roushdy, Tamer, additional

Published
2023
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26. Gender disparity versus equality in acute stroke: a Middle Eastern country hospital-based study.

Author

George, John, Aref, Hany, Nasser, Azza Abdel, Nasef, Ayman, Elbassiouny, Ahmed, and Roushdy, Tamer

Subjects
STROKE units, GENDER inequality, ISCHEMIC stroke, GENDER differences (Sociology), HOSPITALIZATION insurance, ATRIAL fibrillation
Abstract

Background: Acute stroke management is well-established in developed countries with no gender difference. Yet, in developing countries there are reports on gender disparity in medical services including stroke services. Egypt, a developing low–middle-income country, heavily populated, in the Middle East is a good example to answer whether acute ischemic stroke service is provided equally to males and females or there is disparity in risk factors, onset to door (OTD), door to needle (DTN), and outcome. The current study was prospective observational analytical hospital-based study, on acute ischemic stroke cases admitted to Nasr city insurance hospital stroke unit between September 2020 and September 2022. Results: 350 cases were included, 257 males and 93 females. Hypertension was the commonest risk factor 66% males and 81% females P = 0.011, atrial fibrillation was predominant in females P < 0.001, smoking was predominant in males P < 0.001. Median OTD in hours was 8.0 among both genders with minimum zero and maximum 96 h in males compared to minimum 1 and maximum 120 h in females, DTN was around 30 min with no significant difference. Median NIHSS on which rtPA was administered was 12.5 (6–13) in females compared to 10 (6–12) in males. Males who did not receive rtPA had a better mRS on discharge and on 90 days P = 0.01, 0.009, respectively, while there was no significant difference on discharge and 90 days between both genders on receiving rtPA. Conclusions: No gender disparity was found in DTN, discharge outcome, and 90 days among rtPA recipients. Females tended to have higher NIHSS and relatively delayed presentation to ER with less favorable outcome at discharge and 90 days in case of not receiving rtPA. Encouraging earlier arrival and conducting awareness campaigns for risk factors management is warranted. [ABSTRACT FROM AUTHOR]

Published
2023
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28. Global Impact of COVID-19 on Stroke Care and Intravenous Thrombolysis

Author

Nogueira, Raul G, Qureshi, Muhammed M, Abdalkader, Mohamad, Martins, Sheila Ouriques, Yamagami, Hiroshi, Qiu, Zhongming, Mansour, Ossama Yassin, Sathya, Anvitha, Czlonkowska, Anna, Tsivgoulis, Georgios, Aguiar de Sousa, Diana, Demeestere, Jelle, Mikulik, Robert, Vanacker, Peter, Siegler, James E, Kõrv, Janika, Biller, Jose, Liang, Conrad W, Sangha, Navdeep S, Zha, Alicia M, Czap, Alexandra L, Holmstedt, Christine Anne, Turan, Tanya N, Ntaios, George, Malhotra, Konark, Tayal, Ashis, Loochtan, Aaron, Ranta, Annamarei, Mistry, Eva A, Alexandrov, Anne W, Huang, David Y, Yaghi, Shadi, Raz, Eytan, Sheth, Sunil A, Mohammaden, Mahmoud H, Frankel, Michael, Bila Lamou, Eric Guemekane, Aref, Hany M, Elbassiouny, Ahmed, Hassan, Farouk, Menecie, Tarek, Mustafa, Wessam, Shokri, Hossam M, Roushdy, Tamer, Sarfo, Fred S, Alabi, Tolulope Oyetunde, Arabambi, Babawale, Nwazor, Ernest O, Sunmonu, Taofiki Ajao, Wahab, Kolawole, Yaria, Joseph, Mohammed, Haytham Hussein, Adebayo, Philip B, Riahi, Anis D, Ben Sassi, Samia, Gwaunza, Lenon, Ngwende, Gift Wilson, Sahakyan, David, Rahman, Aminur, Ai, Zhibing, Bai, Fanghui, Duan, Zhenhui, Hao, Yonggang, Huang, Wenguo, Li, Guangwen, Li, Wei, Liu, Ganzhe, Luo, Jun, Shang, Xianjin, Sui, Yi, Tian, Ling, Wen, Hongbin, Wu, Bo, Yan, Yuying, Yuan, Zhengzhou, Zhang, Hao, Zhang, Jun, Zhao, Wenlong, Zi, Wenjie, Leung, Thomas W, Chugh, Chandril, Huded, Vikram, Menon, Bindu, Pandian, Jeyaraj Durai, Sylaja, P N, Usman, Fritz Sumantri, Farhoudi, Mehdi, Hokmabadi, Elyar Sadeghi, Horev, Anat, Reznik, Anna, Hoffmann, Rotem Sivan, Ohara, Nobuyuki, Sakai, Nobuyuki, Watanabe, Daisuke, Yamamoto, Ryoo, Doijiri, Ryosuke, Tokuda, Naoki, Yamada, Takehiro, Terasaki, Tadashi, Yazawa, Yukako, Uwatoko, Takeshi, Dembo, Tomohisa, Shimizu, Hisao, Sugiura, Yuri, Miyashita, Fumio, Fukuda, Hiroki, Miyake, Kosuke, Shimbo, Junsuke, Sugimura, Yusuke, Yagita, Yoshiki, Takenobu, Yohei, Matsumaru, Yuji, Yamada, Satoshi, Kono, Ryuhei, Kanamaru, Takuya, Yamazaki, Hidekazu, Sakaguchi, Manabu, Todo, Kenichi, Yamamoto, Nobuaki, Sonoda, Kazutaka, Yoshida, Tomoko, Hashimoto, Hiroyuki, Nakahara, Ichiro, Kondybayeva, Aida, Faizullina, Kamila, Kamenova, Saltanat, Zhanuzakov, Murat, Baek, Jang-Hyun, Hwang, Yangha, Lee, Jin Soo, Lee, Si Baek, Moon, Jusun, Park, Hyungjong, Seo, Jung Hwa, Seo, Kwon-Duk, Sohn, Sung Il, Young, Chang Jun, Ahdab, Rechdi, Wan Zaidi, Wan Asyraf, Aziz, Zariah Abdul, Basri, Hamidon Bin, Chung, Law Wan, Ibrahim, Aznita Binti, Ibrahim, Khairul Azmi, Looi, Irene, Tan, Wee Yong, Yahya, Nafisah Wan, Groppa, Stanislav, Leahu, Pavel, Al Hashmi, Amal M, Imam, Yahia Zakaria, Akhtar, Naveed, Pineda-Franks, Maria Carissa, Co, Christian Oliver, Kandyba, Dmitriy, Alhazzani, Adel, Al-Jehani, Hosam, Tham, Carol Huilian, Mamauag, Marlie Jane, Venketasubramanian, Narayanaswamy, Chen, Chih-Hao, Tang, Sung-Chun, Churojana, Anchalee, Akil, Esref, Aykaç, Ozlem, Ozdemir, Atilla Ozcan, Giray, Semih, Hussain, Syed Irteza, John, Seby, Le Vu, Huynh, Tran, Anh Duc, Nguyen, Huy Hoang, Pham, Thong Nhu, Nguyen, Thang Huy, Nguyen, Trung Quoc, Gattringer, Thomas, Enzinger, Christian, Killer-Oberpfalzer, Monika, Bellante, Flavio, De Blauwe, Sofie, Vanhooren, Geert, De Raedt, Sylvie, Dusart, Anne, Lemmens, Robin, Ligot, Noemie, Rutgers, Matthieu Pierre, Yperzeele, Laetitia, Alexiev, Filip, Sakelarova, Teodora, Bedeković, Marina Roje, Budincevic, Hrvoje, Cindrić, Igor, Hucika, Zlatko, Ozretic, David, Saric, Majda Seferovic, Pfeifer, Frantiek, Karpowic, Igor, Cernik, David, Sramek, Martin, Skoda, Miroslav, Hlavacova, Helena, Klecka, Lukas, Koutny, Martin, Vaclavik, Daniel, Skoda, Ondrej, Fiksa, Jan, Hanelova, Katerina, Nevsimalova, Miroslava, Rezek, Robert, Prochazka, Petr, Krejstova, Gabriela, Neumann, Jiri, Vachova, Marta, Brzezanski, Henryk, Hlinovsky, David, Tenora, Dusan, Jura, Rene, Jurák, Lubomír, Novak, Jan, Novak, Ales, Topinka, Zdenek, Fibrich, Petr, Sobolova, Helena, Volny, Ondrej, Christensen, Hanne Krarup, Drenck, Nicolas, Iversen, Helle Klingenberg, Simonsen, Claus Z, Truelsen, Thomas Clement, Wienecke, Troels, Vibo, Riina, Gross-Paju, Katrin, Toomsoo, Toomas, Antsov, Katrin, Caparros, Francois, Cordonnier, Charlotte, Dan, Maria, Faucheux, Jean-Marc, Mechtouff, Laura, Eker, Omer, Lesaine, Emilie, Ondze, Basile, Peres, Roxane, Pico, Fernando, Piotin, Michel, Pop, Raoul, Rouanet, Francois, Gubeladze, Tatuli, Khinikadze, Mirza, Lobjanidze, Nino, Tsikaridze, Alexander, Nagel, Simon, Ringleb, Peter Arthur, Rosenkranz, Michael, Schmidt, Holger, Sedghi, Annahita, Siepmann, Timo, Szabo, Kristina, Thomalla, Götz, Palaiodimou, Lina, Sagris, Dimitrios, Kargiotis, Odysseas, Klivenyi, Peter, Szapary, Laszlo, Tarkanyi, Gabor, Adami, Alessandro, Bandini, Fabio, Calabresi, Paolo, Frisullo, Giovanni, Renieri, Leonardo, Sangalli, Davide, Pirson, Anne V, Uyttenboogaart, Maarten, van den Wijngaard, Ido, Kristoffersen, Espen Saxhaug, Brola, Waldemar, Fudala, Małgorzata, Horoch-Lyszczarek, Ewa, Karlinski, Michal, Kazmierski, Radoslaw, Kram, Pawel, Rogoziewicz, Marcin, Kaczorowski, Rafal, Luchowski, Piotr, Sienkiewicz-Jarosz, Halina, Sobolewski, Piotr, Fryze, Waldemar, Wisniewska, Anna, Wiszniewska, Malgorzata, Ferreira, Patricia, Ferreira, Paulo, Fonseca, Luisa, Marto, João Pedro, Pinho E Melo, Teresa, Nunes, Ana Paiva, Rodrigues, Miguel, Cruz, Vítor Tedim, Falup-Pecurariu, Cristian, Krastev, Georgi, Mako, Miroslav, Alonso de Leciñana, María, Arenillas, Juan F, Ayo-Martin, Oscar, Culebras, Antonio Cruz, Tejedor, Exuperio Diez, Montaner, Joan, Pérez-Sánchez, Soledad, Tola Arribas, Miguel Angel, Vasquez, Alejandro Rodriguez, Mazya, Michael, Bernava, Gianmarco, Brehm, Alex, Machi, Paolo, Fischer, Urs, Gralla, Jan, Michel, Patrik L, Psychogios, Marios-Nikos, Strambo, Davide, Banerjee, Soma, Krishnan, Kailash, Kwan, Joseph, Butt, Asif, Catanese, Luciana, Demchuk, Andrew, Field, Thalia, Haynes, Jennifer, Hill, Michael D, Khosravani, Houman, Mackey, Ariane, Pikula, Aleksandra, Saposnik, Gustavo, Scott, Courtney Anne, Shoamanesh, Ashkan, Shuaib, Ashfaq, Yip, Samuel, Barboza, Miguel A, Barrientos, Jose Domingo, Portillo Rivera, Ligia Ibeth, Gongora-Rivera, Fernando, Novarro-Escudero, Nelson, Blanco, Anmylene, Abraham, Michael, Alsbrook, Diana, Altschul, Dorothea, Alvarado-Ortiz, Anthony J, Bach, Ivo, Badruddin, Aamir, Barazangi, Nobl, Brereton, Charmaine, Castonguay, Alicia, Chaturvedi, Seemant, Chaudhry, Saqib A, Choe, Hana, Choi, Jae H, Dharmadhikari, Sushrut, Desai, Kinjal, Devlin, Thomas G, Doss, Vinodh T, Edgell, Randall, Etherton, Mark, Farooqui, Mudassir, Frei, Don, Gandhi, Dheeraj, Grigoryan, Mikayel, Gupta, Rishi, Hassan, Ameer E, Helenius, Johanna, Kaliaev, Artem, Kaushal, Ritesh, Khandelwal, Priyank, Khawaja, Ayaz M, Khoury, Naim N, Kim, Benny S, Kleindorfer, Dawn O, Koyfman, Feliks, Lee, Vivien H, Leung, Lester Y, Linares, Guillermo, Linfante, Italo, Lutsep, Helmi L, Macdougall, Lisa, Male, Shailesh, Malik, Amer, Masoud, Hesham, McDermott, Molly, Mehta, Brijesh P, Min, Jiangyong, Mittal, Manoj, Morris, Jane G, Multani, Sumeet S, Nahab, Fadi, Nalleballe, Krishna, Nguyen, Claude B, Novakovic-White, Roberta, Ortega-Gutierrez, Santiago, Rahangdale, Rahul H, Ramakrishnan, Pankajavalli, Romero, Jose Rafael, Rost, Natalia, Rothstein, Aaron, Ruland, Sean, Shah, Ruchir, Sharma, Malveeka, Silver, Brian, Simmons, Marc, Singh, Abhishek, Starosciak, Amy K, Strasser, Sheryl L, Szeder, Viktor, Teleb, Mohamed, Tsai, Jenny P, Voetsch, Barbara, Balaguera, Oscar, Pujol Lereis, Virginia A, Luraschi, Adriana, Almeida, Marcele Schettini, Cardoso, Fabricio Buchdid, Conforto, Adriana, De Deus Silva, Leonardo, Giacomini, Luidia Varrone, Lima, Fabricio Oliveira, Longo, Alexandre L, Magalhães, Pedro Sc, Martins, Rodrigo Targa, Mont'alverne, Francisco, Mora Cuervo, Daissy Liliana, Rebello, Leticia Costa, Valler, Lenise, Zetola, Viviane Flumignan, Lavados, Pablo M, Navia, Victor, Olavarría, Verónica V, Almeida Toro, Juan Manuel, Ricardo Amaya, Pablo Felipe, Bayona, Hernan, Corredor-Quintero, Angel Basilio, Rivera Ordonez, Carlos Eduardo, Mantilla Barbosa, Diana Katherine, Lara, Osvaldo, Patiño, Mauricio R, Diaz Escobar, Luis Fernando, Dejesus Melgarejo Farina, Donoband Edson, Villamayor, Analia Cardozo, Zelaya Zarza, Adolfo Javier, Barrientos Iman, Danny Moises, Kadota, Liliana Rodriguez, Campbell, Bruce, Hankey, Graeme J, Hair, Casey, Kleinig, Timothy, Ma, Alice, Martins, Rodrigo Tomazini, Sahathevan, Ramesh, Thijs, Vincent, Salazar, Daniel, Yuan-Hao Wu, Teddy, Haussen, Diogo C, Liebeskind, David, Yavagal, Dileep, Jovin, Tudor G, Zaidat, Osama O, and Nguyen, Thanh N

Subjects
610 Medicine & health
Abstract

OBJECTIVE The objectives of this study were to measure the global impact of the pandemic on the volumes for intravenous thrombolysis (IVT), IVT transfers, and stroke hospitalizations over 4 months at the height of the pandemic (March 1 to June 30, 2020) compared with two control 4-month periods. METHODS We conducted a cross-sectional, observational, retrospective study across 6 continents, 70 countries, and 457 stroke centers. Diagnoses were identified by their ICD-10 codes and/or classifications in stroke databases. RESULTS There were 91,373 stroke admissions in the 4 months immediately before compared to 80,894 admissions during the pandemic months, representing an 11.5% (95%CI, -11.7 to - 11.3, p

Published
2021
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30. Safety and efficacy of balloon-mounted stent in the treatment of symptomatic intracranial atherosclerotic disease: a multicenter experience

Author

Mohammaden, Mahmoud H, primary, Nogueira, Raul G, additional, Tekle, Wondwossen, additional, Ortega-Gutierrez, Santiago, additional, Farooqui, Mudassir, additional, Zevallos, Cynthia B., additional, Hanel, Ricardo A, additional, Cortez, Gustavo M, additional, Aghaebrahim, Amin, additional, Starke, Robert M, additional, Aref, Hany, additional, Elbassiouny, Ahmed, additional, Gamea, Ayman, additional, Alaraj, Ali, additional, Sadeh, Morteza, additional, Grigoryan, Mikayel, additional, Kuybu, Okkes, additional, Haussen, Diogo C, additional, Sheth, Sunil A, additional, Maud, Alberto, additional, Cordina, Steve M, additional, Tanweer, Omar, additional, Kan, Peter, additional, Burkhardt, Jan-Karl, additional, Grandhi, Ramesh, additional, Siddiq, Farhan, additional, and Hassan, Ameer E, additional

Published
2021
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31. Global impact of the COVID-19 pandemic on stroke care and intravenous thrombolysis

Author

Thanh Nguyen, Phuong, Qureshi, Muhammad, Martins, Sheila, Yamagami, Hiroshi, Qiu, Zhongming, Mansour, Ossama, Czlonkowska, Anna, Abdalkader, Mohamad, Sathya, Anvitha, de Sousa, Diana Aguiar, Demeestere, Jelle, Mikulik, Robert, Vanacker, Peter, Siegler, James, Korv, Janika, Biller, Jose, Liang, Conrad, Sangha, Navdeep, Zha, Alicia, Czap, Alexandra, Holmstedt, Christine, Turan, Tanya, Grant, Cheryl, Ntaios, George, Malhotra, Konard, Tayal, Ashis, Loochtan, Aaron, Mistry, Eva, Alexandrov, Anne, Huang, David, Yaghi, Shadi, Raz, Eytan, Sheth, Sunil, Frankel, Michael, Lamou, Eric Gueumekane Bila, Aref, Hany, Elbassiouny, Ahmed, Hassan, Farouk, Mustafa, Wessam, Menecie, Tarek, Shokri, Hossam, Roushdy, Tamer, Sarfo, Fred Stephen, Alabi, Tolulope, Arabambi, Babawale, Nwazor, Ernest, Sunmonu, Taofiki Ajao, Wahab, Kolawole W., Mohammed, Haythem Hussein, Adebayo, Philip B., Riahi, Anis, Ben Sassi, Samia, Gwaunza, Lenon, Rahman, Aminur, Ai, Zhibing, Bai, Fanghui, Duan, Zhenhui, Hao, Yonggang, Huang, Wenguo, Li, Guangwen, Li, Wei, Liu, Ganzhe, Luo, Jun, Shang, Xianjin, Sui, Yi, Tian, Ling, Wen, Hongbin, Wu, Bo, Yan, Yuying, Yuan, Zhengzhou, Zhang, Hao, Zhang, Jun, Zhao, Wenlong, Zi, Wenjie, Leung, Thomas K., Sahakyan, David, Chugh, Chandril, Huded, Vikram, Menon, Bindu, Pandian, Jeyaraj, Sylaja, P. N., Usman, Fritz Sumantri, Farhoudi, Mehdi, Sadeghi-Hokmabadi, Elyar, Reznik, Anna, Sivan-Hoffman, Rotem, Horev, Anat, Ohara, Nobuyuki, Sakai, Nobuyuki, Watanabe, Daisuke, Yamamoto, Ryoo, Doijiri, Ryosuke, Tokuda, Naoki, Yamada, Takehiro, Terasaki, Tadashi, Yazawa, Yukako, Uwatoko, Takeshi, Dembo, Tomohisa, Shimizu, Hisao, Sugiura, Yuri, Miyashita, Fumio, Fukuda, Hiroki, Miyake, Kosuke, Shimbo, Junsuke, Sugimura, Yusuke, Yagita, Yoshika, Takenobu, Yohei, Matsumaru, Yuji, Yamada, Satoshi, Kono, Ryuhei, Kanamaru, Takuya, Yamazaki, Hidekazu, Sakaguchi, Manabu, Todo, Kenichi, Yamamoto, Nobuaki, Sonodda, Kazutaka, Yoshida, Tomoko, Hashimoto, Hiroyuki, Nakahara, Ichiro, Faizullina, Kamila, Kamenova, Saltanat, Kondybayeva, Aida, Zhanuzakov, Murat, Baek, Jang-Hyun, Hwang, Yangha, Lee, Si Baek, Moon, Jusun, Park, Hyungjong, Seo, Jung Hwa, Seo, Kwon-Duk, Young, Chang Jun, Ahdab, Rechdi, Aziz, Zariah Abdul, Zaidi, Wan Asyraf Wan, Bin Basri, Hamidon, Chung, Law Wan, Husin, Mazlina, Ibrahim, Aznita Binti, Ibrahim, Khairul Azmi, Looi, Irene, Tan, Wee Yong, Yahya, Wan Nur Nafisah Wan, Groppa, Stanislav, Leahu, Pavel, Al Hashmi, Amal, Imam, Yehai Z., Akhtar, Naveed, Oliver, Christian, Kandyba, Dmitriy, Alhazzani, Adel, Al-Jehani, Hosam, Tham, Carol Huilian, Mamauag, Marlie Jane, Narayanaswamy, Ram, Chen, Chih-Hao, Tang, Sung-Chun, Churojana, Anchalee, Aykac, Ozlem, Ozdemir, Atilla Ozcan, Hussain, Syed Irteza, John, Seby, Huynh Le Vu, Anh Duc Tran, Huy Hoang Nguyen, Pham Nhu Thong, Nguyen, Thang, Nguyen, Trung, Gattringer, Thomas, Enzinger, Christian, Killer-Oberpfalzer, Monika, Bellante, Flavio, De Blauwe, Sofie, Van Hooren, Geert, De Raedt, Sylvie, Dusart, Anne, Ligot, Noemie, Rutgers, Matthieu, Yperzeele, Laetitia, Alexiev, Filip, Sakelarova, Teodora, Bedekovic, Marina Roje, Budincevic, Hrvoje, Cindric, Igor, Hucika, Zlatko, Ozretic, David, Saric, Majda Seferovic, Pfeifer, Frantisek, Karpowicz, Igor, Cernik, David, Sramek, Martin, Skoda, Miroslav, Hlavacova, Helena, Klecka, Lukas, Koutny, Martin, Vaclavik, Dan, Skoda, Ondrej, Fiksa, Jan, Hanelova, Katerina, Nevsimalova, Miroslava, Rezek, Robert, Prochazka, Petr, Krejstova, Gabriela, Neumann, Jiri, Vachova, Marta, Brzezanski, Henry, Hlinovsky, David, Tenora, Dusan, Jura, Rene, Jurak, Lubomir, Novak, Jan, Novak, Ales, Topinka, Zdenek, Fibrich, Petr, Sobolova, Helena, Volny, Ondrej, Christensen, Hanne Krarup, Drenck, Nicolas, Iversen, Helle, Simonsen, Claus, Truelsen, Thomas, Wienecke, Troels, Vibo, Riina, Gross-Paju, Katrin, Toomsoo, Toomas, Antsov, Katrin, Caparros, Francois, Cordonnier, Charlotte, Dan, Maria, Faucheux, Jean-Marc, Mechtouff, Laura, Eker, Omer, Lesaine, Emillie, Ondze, Basile, Pico, Fernando, Pop, Raoul, Rouanet, Francois, Gubeladze, Tatuli, Khinikadze, Mirza, Lobjanidze, Nina, Tsiskaridze, Alexander, Nagel, Simon, Ringleb, Peter Arthur, Rosenkranz, Michael, Schmidt, Holger, Sedghi, Annahita, Siepmann, Timo, Szabo, Kristina, Thomalla, Gotz, Palaiodimou, Lina, Sagris, Dimitrios, Kargiotis, Odysseas, Kaliaev, Artem, Liebeskind, David, Hassan, Ameer, Ranta, Anna, Devlin, Thomas, Zaidat, Osama, Castonguay, Alicia, Jovin, Tudor, Tsivgoulis, Georgios, Malik, Amer, Ma, Alice, Campbell, Bruce, Kleinig, Timothy, Wu, Teddy, Gongora, Fernando, Lavados, Pablo, Olavarria, Veronica, Lereis, Virginia Pujol, Corredor, Angel, Barbosa, Diana Mantilla, Bayona, Hernan, Barrientos, Jose Domingo, Patino, Mauricio, Thijs, Vincent, Pirson, Anne, Kristoffersen, Espen Saxhaug, Patrik, Michel, Fischer, Urs, Bernava, Gianmarco, Renieri, Leonardo, Strambo, Davide, Ayo-Martin, Oscar, Montaner, Joan, Karlinski, Michal, Cruz-Culebras, Antonio, Luchowski, Piotr, Krastev, Georgi, Arenillas, Juan, Gralla, Jan, Mangiafico, Salvatore, Blasco, Jordi, Fonseca, Luisa, Silva, M. Luis, Kwan, Joseph, Banerjee, Soma, Sangalli, Davide, Frisullo, Giovanni, Yavagal, Dileep, Uyttenboogaart, Maarten, Bandini, Fabio, Adami, Alessandro, de Lecina, Maria Alonso, Arribas, Miguel Angel Tola, Ferreira, Paulo, Cruz, Vitor Tedim, Nunes, Ana Paiva, Marto, Joao Pedro, Rodrigues, Miguel, Melo, Teresa, Saposnik, Gustavo, Scott, Courtney Anne, Shuaib, Ashfaq, Khosravani, Houman, Fields, Thalia, Shoamanesh, Ashkan, Catanese, Luciana, Mackey, Ariane, Hill, Michael, Etherton, Mark, Rost, Natalia, Lutsep, Helmi, Lee, Vivien, Mehta, Brijesh, Pikula, Aleksandra, Simmons, Marc, Macdougall, Lisa, Silver, Brian, Khandelwal, Priyank, Morris, Jane, Novakovic-White, Roberta, Ramakrishnan, Pankajavalli, Shah, Ruchir, Altschul, Dorothea, Almufti, Fawaz, Amaya, Pablo, Ordonez, Carlos Eduardo Rivera, Lara, Osvalda, Kadota, Liliana Rodriguez, Rivera, Ligia Ibeth Portillo, Novarro, Nelson, Escobar, Luis Diaz, Melgarejo, Donoband, Cardozo, Analia, Blanco, Anmylene, Zelaya, Javier Adolfo, Luraschi, Adriana, Gonzalez, Victor Hugo Navia, Almeida, Juan, Conforto, Adriana, Almeida, Marcele Schettini, Silva, Leonardo de Deus, Cuervo, Daissy Liliana Mora, Zetola, Viviane Flumignan, Martins, Rodrigo Targa, Valler, Lenise, Giacomini, Luidia Varrone, Cardoso, Fabricio Buchdid, Sahathevan, Ramesh, Hair, Casey, Hankey, Graeme, Salazar, Daniel, Lima, Fabricio Oliveira, Mont'Alverne, Francisco, Moises, Danny, Iman, Barrientos, Magalhaes, Pedro, Longo, Alexandre, Rebello, Leticia, Falup-Pecurariu, Cristian, Mazya, Michael, Wisniewska, Anna, Fryze, Waldemar, Kazmierski, Radoslaw, Wisniewska, Malgorzata, Horoch, Ewa, Sienkiewicz-Jarosz, Halina, Fudala, Malgorzata, Rogoziewicz, Marcin, Brola, Waldemar, Sobolewski, Piotr, Kaczorowski, Rafal, Stepien, Adam, Klivenyi, Peter, Szapary, Laszlo, van den Wijngaard, Ido, Demchuk, Andrew, Abraham, Michael, Alvarado-Ortiz, Tony, Kaushal, Ritesh, Ortega-Gutierrez, Santiago, Farooqui, Mudassir, Bach, Ivo, Badruddin, Aamir, Barazangi, Nobl, Nguyen, Claude, Brereton, Charmaine, Choi, Jae H., Dharmadhikari, Sushrut, Desai, Kinjal, Doss, Vinodh, Edgell, Randall, Linares, Guillermo, Frei, Donald, Chaturvedi, Seemant, Gandhi, Dheeraj, Chaudhry, Saqib, Choe, Hana, Grigoryan, Mikayel, Gupta, Rishi, Helenius, Johanna, Voetsch, Barbara, Khwaja, Ayaz, Khoury, Naim, Kim, Benny S., Kleindorfer, Dawn, McDermott, Molly, Koyfman, Feliks, Leung, Lester, Linfante, Italo, Male, Shailesh, Masoud, Hesham, Min, Jiangyong, Mittal, Manoj, Multani, Sumeet, Nahab, Fadi, Nalleballe, Krishna, Rahangdale, Rahul, Rafael, Jose, Rothstein, Aaron, Ruland, Sean, Sharma, Malveeka, Singh, Abishek, Starosciak, Amy, Strasser, Sheryl, Szeder, Viktor, Teleb, Mohamed, Tsai, Jenny, Mohammaden, Mahmoud, Pineda-Franks, Carissa, Asyraf, Wan, Trung Quoch Nguyen, Tarkanyi, Gabor, Haussen, Diogo, Balaguera, Oscar, Vasquez, Alejandro Rodriguez, Nogueira, Raul, Thanh Nguyen, Phuong, Qureshi, Muhammad, Martins, Sheila, Yamagami, Hiroshi, Qiu, Zhongming, Mansour, Ossama, Czlonkowska, Anna, Abdalkader, Mohamad, Sathya, Anvitha, de Sousa, Diana Aguiar, Demeestere, Jelle, Mikulik, Robert, Vanacker, Peter, Siegler, James, Korv, Janika, Biller, Jose, Liang, Conrad, Sangha, Navdeep, Zha, Alicia, Czap, Alexandra, Holmstedt, Christine, Turan, Tanya, Grant, Cheryl, Ntaios, George, Malhotra, Konard, Tayal, Ashis, Loochtan, Aaron, Mistry, Eva, Alexandrov, Anne, Huang, David, Yaghi, Shadi, Raz, Eytan, Sheth, Sunil, Frankel, Michael, Lamou, Eric Gueumekane Bila, Aref, Hany, Elbassiouny, Ahmed, Hassan, Farouk, Mustafa, Wessam, Menecie, Tarek, Shokri, Hossam, Roushdy, Tamer, Sarfo, Fred Stephen, Alabi, Tolulope, Arabambi, Babawale, Nwazor, Ernest, Sunmonu, Taofiki Ajao, Wahab, Kolawole W., Mohammed, Haythem Hussein, Adebayo, Philip B., Riahi, Anis, Ben Sassi, Samia, Gwaunza, Lenon, Rahman, Aminur, Ai, Zhibing, Bai, Fanghui, Duan, Zhenhui, Hao, Yonggang, Huang, Wenguo, Li, Guangwen, Li, Wei, Liu, Ganzhe, Luo, Jun, Shang, Xianjin, Sui, Yi, Tian, Ling, Wen, Hongbin, Wu, Bo, Yan, Yuying, Yuan, Zhengzhou, Zhang, Hao, Zhang, Jun, Zhao, Wenlong, Zi, Wenjie, Leung, Thomas K., Sahakyan, David, Chugh, Chandril, Huded, Vikram, Menon, Bindu, Pandian, Jeyaraj, Sylaja, P. N., Usman, Fritz Sumantri, Farhoudi, Mehdi, Sadeghi-Hokmabadi, Elyar, Reznik, Anna, Sivan-Hoffman, Rotem, Horev, Anat, Ohara, Nobuyuki, Sakai, Nobuyuki, Watanabe, Daisuke, Yamamoto, Ryoo, Doijiri, Ryosuke, Tokuda, Naoki, Yamada, Takehiro, Terasaki, Tadashi, Yazawa, Yukako, Uwatoko, Takeshi, Dembo, Tomohisa, Shimizu, Hisao, Sugiura, Yuri, Miyashita, Fumio, Fukuda, Hiroki, Miyake, Kosuke, Shimbo, Junsuke, Sugimura, Yusuke, Yagita, Yoshika, Takenobu, Yohei, Matsumaru, Yuji, Yamada, Satoshi, Kono, Ryuhei, Kanamaru, Takuya, Yamazaki, Hidekazu, Sakaguchi, Manabu, Todo, Kenichi, Yamamoto, Nobuaki, Sonodda, Kazutaka, Yoshida, Tomoko, Hashimoto, Hiroyuki, Nakahara, Ichiro, Faizullina, Kamila, Kamenova, Saltanat, Kondybayeva, Aida, Zhanuzakov, Murat, Baek, Jang-Hyun, Hwang, Yangha, Lee, Si Baek, Moon, Jusun, Park, Hyungjong, Seo, Jung Hwa, Seo, Kwon-Duk, Young, Chang Jun, Ahdab, Rechdi, Aziz, Zariah Abdul, Zaidi, Wan Asyraf Wan, Bin Basri, Hamidon, Chung, Law Wan, Husin, Mazlina, Ibrahim, Aznita Binti, Ibrahim, Khairul Azmi, Looi, Irene, Tan, Wee Yong, Yahya, Wan Nur Nafisah Wan, Groppa, Stanislav, Leahu, Pavel, Al Hashmi, Amal, Imam, Yehai Z., Akhtar, Naveed, Oliver, Christian, Kandyba, Dmitriy, Alhazzani, Adel, Al-Jehani, Hosam, Tham, Carol Huilian, Mamauag, Marlie Jane, Narayanaswamy, Ram, Chen, Chih-Hao, Tang, Sung-Chun, Churojana, Anchalee, Aykac, Ozlem, Ozdemir, Atilla Ozcan, Hussain, Syed Irteza, John, Seby, Huynh Le Vu, Anh Duc Tran, Huy Hoang Nguyen, Pham Nhu Thong, Nguyen, Thang, Nguyen, Trung, Gattringer, Thomas, Enzinger, Christian, Killer-Oberpfalzer, Monika, Bellante, Flavio, De Blauwe, Sofie, Van Hooren, Geert, De Raedt, Sylvie, Dusart, Anne, Ligot, Noemie, Rutgers, Matthieu, Yperzeele, Laetitia, Alexiev, Filip, Sakelarova, Teodora, Bedekovic, Marina Roje, Budincevic, Hrvoje, Cindric, Igor, Hucika, Zlatko, Ozretic, David, Saric, Majda Seferovic, Pfeifer, Frantisek, Karpowicz, Igor, Cernik, David, Sramek, Martin, Skoda, Miroslav, Hlavacova, Helena, Klecka, Lukas, Koutny, Martin, Vaclavik, Dan, Skoda, Ondrej, Fiksa, Jan, Hanelova, Katerina, Nevsimalova, Miroslava, Rezek, Robert, Prochazka, Petr, Krejstova, Gabriela, Neumann, Jiri, Vachova, Marta, Brzezanski, Henry, Hlinovsky, David, Tenora, Dusan, Jura, Rene, Jurak, Lubomir, Novak, Jan, Novak, Ales, Topinka, Zdenek, Fibrich, Petr, Sobolova, Helena, Volny, Ondrej, Christensen, Hanne Krarup, Drenck, Nicolas, Iversen, Helle, Simonsen, Claus, Truelsen, Thomas, Wienecke, Troels, Vibo, Riina, Gross-Paju, Katrin, Toomsoo, Toomas, Antsov, Katrin, Caparros, Francois, Cordonnier, Charlotte, Dan, Maria, Faucheux, Jean-Marc, Mechtouff, Laura, Eker, Omer, Lesaine, Emillie, Ondze, Basile, Pico, Fernando, Pop, Raoul, Rouanet, Francois, Gubeladze, Tatuli, Khinikadze, Mirza, Lobjanidze, Nina, Tsiskaridze, Alexander, Nagel, Simon, Ringleb, Peter Arthur, Rosenkranz, Michael, Schmidt, Holger, Sedghi, Annahita, Siepmann, Timo, Szabo, Kristina, Thomalla, Gotz, Palaiodimou, Lina, Sagris, Dimitrios, Kargiotis, Odysseas, Kaliaev, Artem, Liebeskind, David, Hassan, Ameer, Ranta, Anna, Devlin, Thomas, Zaidat, Osama, Castonguay, Alicia, Jovin, Tudor, Tsivgoulis, Georgios, Malik, Amer, Ma, Alice, Campbell, Bruce, Kleinig, Timothy, Wu, Teddy, Gongora, Fernando, Lavados, Pablo, Olavarria, Veronica, Lereis, Virginia Pujol, Corredor, Angel, Barbosa, Diana Mantilla, Bayona, Hernan, Barrientos, Jose Domingo, Patino, Mauricio, Thijs, Vincent, Pirson, Anne, Kristoffersen, Espen Saxhaug, Patrik, Michel, Fischer, Urs, Bernava, Gianmarco, Renieri, Leonardo, Strambo, Davide, Ayo-Martin, Oscar, Montaner, Joan, Karlinski, Michal, Cruz-Culebras, Antonio, Luchowski, Piotr, Krastev, Georgi, Arenillas, Juan, Gralla, Jan, Mangiafico, Salvatore, Blasco, Jordi, Fonseca, Luisa, Silva, M. Luis, Kwan, Joseph, Banerjee, Soma, Sangalli, Davide, Frisullo, Giovanni, Yavagal, Dileep, Uyttenboogaart, Maarten, Bandini, Fabio, Adami, Alessandro, de Lecina, Maria Alonso, Arribas, Miguel Angel Tola, Ferreira, Paulo, Cruz, Vitor Tedim, Nunes, Ana Paiva, Marto, Joao Pedro, Rodrigues, Miguel, Melo, Teresa, Saposnik, Gustavo, Scott, Courtney Anne, Shuaib, Ashfaq, Khosravani, Houman, Fields, Thalia, Shoamanesh, Ashkan, Catanese, Luciana, Mackey, Ariane, Hill, Michael, Etherton, Mark, Rost, Natalia, Lutsep, Helmi, Lee, Vivien, Mehta, Brijesh, Pikula, Aleksandra, Simmons, Marc, Macdougall, Lisa, Silver, Brian, Khandelwal, Priyank, Morris, Jane, Novakovic-White, Roberta, Ramakrishnan, Pankajavalli, Shah, Ruchir, Altschul, Dorothea, Almufti, Fawaz, Amaya, Pablo, Ordonez, Carlos Eduardo Rivera, Lara, Osvalda, Kadota, Liliana Rodriguez, Rivera, Ligia Ibeth Portillo, Novarro, Nelson, Escobar, Luis Diaz, Melgarejo, Donoband, Cardozo, Analia, Blanco, Anmylene, Zelaya, Javier Adolfo, Luraschi, Adriana, Gonzalez, Victor Hugo Navia, Almeida, Juan, Conforto, Adriana, Almeida, Marcele Schettini, Silva, Leonardo de Deus, Cuervo, Daissy Liliana Mora, Zetola, Viviane Flumignan, Martins, Rodrigo Targa, Valler, Lenise, Giacomini, Luidia Varrone, Cardoso, Fabricio Buchdid, Sahathevan, Ramesh, Hair, Casey, Hankey, Graeme, Salazar, Daniel, Lima, Fabricio Oliveira, Mont'Alverne, Francisco, Moises, Danny, Iman, Barrientos, Magalhaes, Pedro, Longo, Alexandre, Rebello, Leticia, Falup-Pecurariu, Cristian, Mazya, Michael, Wisniewska, Anna, Fryze, Waldemar, Kazmierski, Radoslaw, Wisniewska, Malgorzata, Horoch, Ewa, Sienkiewicz-Jarosz, Halina, Fudala, Malgorzata, Rogoziewicz, Marcin, Brola, Waldemar, Sobolewski, Piotr, Kaczorowski, Rafal, Stepien, Adam, Klivenyi, Peter, Szapary, Laszlo, van den Wijngaard, Ido, Demchuk, Andrew, Abraham, Michael, Alvarado-Ortiz, Tony, Kaushal, Ritesh, Ortega-Gutierrez, Santiago, Farooqui, Mudassir, Bach, Ivo, Badruddin, Aamir, Barazangi, Nobl, Nguyen, Claude, Brereton, Charmaine, Choi, Jae H., Dharmadhikari, Sushrut, Desai, Kinjal, Doss, Vinodh, Edgell, Randall, Linares, Guillermo, Frei, Donald, Chaturvedi, Seemant, Gandhi, Dheeraj, Chaudhry, Saqib, Choe, Hana, Grigoryan, Mikayel, Gupta, Rishi, Helenius, Johanna, Voetsch, Barbara, Khwaja, Ayaz, Khoury, Naim, Kim, Benny S., Kleindorfer, Dawn, McDermott, Molly, Koyfman, Feliks, Leung, Lester, Linfante, Italo, Male, Shailesh, Masoud, Hesham, Min, Jiangyong, Mittal, Manoj, Multani, Sumeet, Nahab, Fadi, Nalleballe, Krishna, Rahangdale, Rahul, Rafael, Jose, Rothstein, Aaron, Ruland, Sean, Sharma, Malveeka, Singh, Abishek, Starosciak, Amy, Strasser, Sheryl, Szeder, Viktor, Teleb, Mohamed, Tsai, Jenny, Mohammaden, Mahmoud, Pineda-Franks, Carissa, Asyraf, Wan, Trung Quoch Nguyen, Tarkanyi, Gabor, Haussen, Diogo, Balaguera, Oscar, Vasquez, Alejandro Rodriguez, and Nogueira, Raul

Published
2021

32. Global impact of the COVID-19 pandemic on stroke care and intravenous thrombolysis (1462)

Author

Nguyen, Thanh, primary, Qureshi, Muhammad, additional, Martins, Sheila, additional, Yamagami, Hiroshi, additional, Qiu, Zhongming, additional, Mansour, Ossama, additional, Czlonkowska, Anna, additional, Abdalkader, Mohamad, additional, Sathya, Anvitha, additional, de Sousa, Diana Aguiar, additional, Demeestere, Jelle, additional, Mikulik, Robert, additional, Vanacker, Peter, additional, Siegler, James, additional, Korv, Janika, additional, Biller, Jose, additional, Liang, Conrad, additional, Sangha, Navdeep, additional, Zha, Alicia, additional, Czap, Alexandra, additional, Holmstedt, Christine, additional, Turan, Tanya, additional, Grant, Cheryl, additional, Ntaios, George, additional, Malhotra, Konard, additional, Tayal, Ashis, additional, Loochtan, Aaron, additional, Mistry, Eva, additional, Alexandrov, Anne, additional, Huang, David, additional, Yaghi, Shadi, additional, Raz, Eytan, additional, Sheth, Sunil, additional, Frankel, Michael, additional, Lamou, Eric Gueumekane Bila, additional, Aref, Hany, additional, Elbassiouny, Ahmed, additional, Hassan, Farouk, additional, Mustafa, Wessam, additional, Menecie, Tarek, additional, Shokri, Hossam, additional, Roushdy, Tamer, additional, Sarfo, Fred Stephen, additional, Alabi, Tolulope, additional, Arabambi, Babawale, additional, Nwazor, Ernest, additional, Sunmonu, Taofiki Ajao, additional, Wahab, Kolawole W., additional, Mohammed, Haythem Hussein, additional, Adebayo, Philip B., additional, Riahi, Anis, additional, Ben Sassi, Samia, additional, Gwaunza, Lenon, additional, Rahman, Aminur, additional, Ai, Zhibing, additional, Bai, Fanghui, additional, Duan, Zhenhui, additional, Hao, Yonggang, additional, Huang, Wenguo, additional, Li, Guangwen, additional, Li, Wei, additional, Liu, Ganzhe, additional, Luo, Jun, additional, Shang, Xianjin, additional, Sui, Yi, additional, Tian, Ling, additional, Wen, Hongbin, additional, Wu, Bo, additional, Yan, Yuying, additional, Yuan, Zhengzhou, additional, Zhang, Hao, additional, Zhang, Jun, additional, Zhao, Wenlong, additional, Zi, Wenjie, additional, Leung, Thomas K., additional, Sahakyan, David, additional, Chugh, Chandril, additional, Huded, Vikram, additional, Menon, Bindu, additional, Pandian, Jeyaraj, additional, Sylaja, P.N., additional, Usman, Fritz Sumantri, additional, Farhoudi, Mehdi, additional, Sadeghi-Hokmabadi, Elyar, additional, Reznik, Anna, additional, Sivan-Hoffman, Rotem, additional, Horev, Anat, additional, Ohara, Nobuyuki, additional, Sakai, Nobuyuki, additional, Watanabe, Daisuke, additional, Yamamoto, Ryoo, additional, Doijiri, Ryosuke, additional, Tokuda, Naoki, additional, Yamada, Takehiro, additional, Terasaki, Tadashi, additional, Yazawa, Yukako, additional, Uwatoko, Takeshi, additional, Dembo, Tomohisa, additional, Shimizu, Hisao, additional, Sugiura, Yuri, additional, Miyashita, Fumio, additional, Fukuda, Hiroki, additional, Miyake, Kosuke, additional, Shimbo, Junsuke, additional, Sugimura, Yusuke, additional, Yagita, Yoshika, additional, Takenobu, Yohei, additional, Matsumaru, Yuji, additional, Yamada, Satoshi, additional, Kono, Ryuhei, additional, Kanamaru, Takuya, additional, Yamazaki, Hidekazu, additional, Sakaguchi, Manabu, additional, Todo, Kenichi, additional, Yamamoto, Nobuaki, additional, Sonodda, Kazutaka, additional, Yoshida, Tomoko, additional, Hashimoto, Hiroyuki, additional, Nakahara, Ichiro, additional, Faizullina, Kamila, additional, Kamenova, Saltanat, additional, Kondybayeva, Aida, additional, Zhanuzakov, Murat, additional, Baek, Jang-Hyun, additional, Hwang, Yangha, additional, Lee, Si Baek, additional, Moon, Jusun, additional, Park, Hyungjong, additional, Seo, Jung Hwa, additional, Seo, Kwon-Duk, additional, Young, Chang Jun, additional, Ahdab, Rechdi, additional, Aziz, Zariah Abdul, additional, Zaidi, Wan Asyraf Wan, additional, Basri, Hamidon Bin, additional, Chung, Law Wan, additional, Husin, Mazlina, additional, Ibrahim, Aznita Binti, additional, Ibrahim, Khairul Azmi, additional, Looi, Irene, additional, Tan, Wee Yong, additional, Yahya, Wan Nur Nafisah Wan, additional, Groppa, Stanislav, additional, Leahu, Pavel, additional, Al Hashmi, Amal, additional, Imam, Yehai Z., additional, Akhtar, Naveed, additional, Oliver, Christian, additional, Kandyba, Dmitriy, additional, Alhazzani, Adel, additional, Al-Jehani, Hosam, additional, Tham, Carol Huilian, additional, Mamauag, Marlie Jane, additional, Narayanaswamy, Ram, additional, Chen, Chih-Hao, additional, Tang, Sung-Chun, additional, Churojana, Anchalee, additional, Aykaç, Ozlem, additional, Özdemir, Atilla Özcan, additional, Hussain, Syed Irteza, additional, John, Seby, additional, Le Vu, Huynh, additional, Tran, Anh Duc, additional, Nguyen, Huy Hoang, additional, Thong, Pham Nhu, additional, Nguyen, Thang, additional, Nguyen, Trung, additional, Gattringer, Thomas, additional, Enzinger, Christian, additional, Killer-Oberpfalzer, Monika, additional, Bellante, Flavio, additional, De Blauwe, Sofie, additional, Van Hooren, Geert, additional, De Raedt, Sylvie, additional, Dusart, Anne, additional, Ligot, Noemie, additional, Rutgers, Matthieu, additional, Yperzeele, Laetitia, additional, Alexiev, Filip, additional, Sakelarova, Teodora, additional, Bedekovic, Marina Roje, additional, Budincevic, Hrvoje, additional, Cindric, Igor, additional, Hucika, Zlatko, additional, Ozretic, David, additional, Saric, Majda Seferovic, additional, Pfeifer, František, additional, Karpowicz, Igor, additional, Cernik, David, additional, Sramek, Martin, additional, Skoda, Miroslav, additional, Hlavacova, Helena, additional, Klecka, Lukas, additional, Koutny, Martin, additional, Vaclavik, Dan, additional, Skoda, Ondrej, additional, Fiksa, Jan, additional, Hanelova, Katerina, additional, Nevsimalova, Miroslava, additional, Rezek, Robert, additional, Prochazka, Petr, additional, Krejstova, Gabriela, additional, Neumann, Jiri, additional, Vachova, Marta, additional, Brzezanski, Henry, additional, Hlinovsky, David, additional, Tenora, Dusan, additional, Jura, Rene, additional, Jurak, Lubomir, additional, Novak, Jan, additional, Novak, Ales, additional, Topinka, Zdenek, additional, Fibrich, Petr, additional, Sobolova, Helena, additional, Volny, Ondrej, additional, Christensen, Hanne Krarup, additional, Drenck, Nicolas, additional, Iversen, Helle, additional, Simonsen, Claus, additional, Truelsen, Thomas, additional, Wienecke, Troels, additional, Vibo, Riina, additional, Gross-Paju, Katrin, additional, Toomsoo, Toomas, additional, Antsov, Katrin, additional, Caparros, Francois, additional, Cordonnier, Charlotte, additional, Dan, Maria, additional, Faucheux, Jean-Marc, additional, Mechtouff, Laura, additional, Eker, Omer, additional, Lesaine, Emillie, additional, Ondze, Basile, additional, Pico, Fernando, additional, Pop, Raoul, additional, Rouanet, Francois, additional, Gubeladze, Tatuli, additional, Khinikadze, Mirza, additional, Lobjanidze, Nina, additional, Tsiskaridze, Alexander, additional, Nagel, Simon, additional, Ringleb, Peter Arthur, additional, Rosenkranz, Michael, additional, Schmidt, Holger, additional, Sedghi, Annahita, additional, Siepmann, Timo, additional, Szabo, Kristina, additional, Thomalla, Gotz, additional, Palaiodimou, Lina, additional, Sagris, Dimitrios, additional, Kargiotis, Odysseas, additional, Kaliaev, Artem, additional, Liebeskind, David, additional, Hassan, Ameer, additional, Ranta, Anna, additional, Devlin, Thomas, additional, Zaidat, Osama, additional, Castonguay, Alicia, additional, Jovin, Tudor, additional, Tsivgoulis, Georgios, additional, Malik, Amer, additional, Ma, Alice, additional, Campbell, Bruce, additional, Kleinig, Timothy, additional, Wu, Teddy, additional, Gongora, Fernando, additional, Lavados, Pablo, additional, Olavarria, Veronica, additional, Lereis, Virginia Pujol, additional, Corredor, Angel, additional, Barbosa, Diana Mantilla, additional, Bayona, Hernan, additional, Barrientos, Jose Domingo, additional, Patino, Mauricio, additional, Thijs, Vincent, additional, Pirson, Anne, additional, Kristoffersen, Espen Saxhaug, additional, Patrik, Michel, additional, Fischer, Urs, additional, Bernava, Gianmarco, additional, Renieri, Leonardo, additional, Strambo, Davide, additional, Ayo-Martin, Oscar, additional, Montaner, Joan, additional, Karlinski, Michal, additional, Cruz-Culebras, Antonio, additional, Luchowski, Piotr, additional, Krastev, Georgi, additional, Arenillas, Juan, additional, Gralla, Jan, additional, Mangiafico, Salvatore, additional, Blasco, Jordi, additional, Fonseca, Luisa, additional, Silva, M. Luis, additional, Kwan, Joseph, additional, Banerjee, Soma, additional, Sangalli, Davide, additional, Frisullo, Giovanni, additional, Yavagal, Dileep, additional, Uyttenboogaart, Maarten, additional, Bandini, Fabio, additional, Adami, Alessandro, additional, de Lecina, Maria Alonso, additional, Arribas, Miguel Angel Tola, additional, Ferreira, Paulo, additional, Cruz, Vitor Tedim, additional, Nunes, Ana Paiva, additional, Marto, Joao Pedro, additional, Rodrigues, Miguel, additional, Melo, Teresa, additional, Saposnik, Gustavo, additional, Scott, Courtney Anne, additional, Shuaib, Ashfaq, additional, Khosravani, Houman, additional, Fields, Thalia, additional, Shoamanesh, Ashkan, additional, Catanese, Luciana, additional, Mackey, Ariane, additional, Hill, Michael, additional, Etherton, Mark, additional, Rost, Natalia, additional, Lutsep, Helmi, additional, Lee, Vivien, additional, Mehta, Brijesh, additional, Pikula, Aleksandra, additional, Simmons, Marc, additional, Macdougall, Lisa, additional, Silver, Brian, additional, Khandelwal, Priyank, additional, Morris, Jane, additional, Novakovic-White, Roberta, additional, Ramakrishnan, Pankajavalli, additional, Shah, Ruchir, additional, Altschul, Dorothea, additional, Almufti, Fawaz, additional, Amaya, Pablo, additional, Ordonez, Carlos Eduardo Rivera, additional, Lara, Osvalda, additional, Kadota, Liliana Rodriguez, additional, Rivera, Ligia Ibeth Portillo, additional, Novarro, Nelson, additional, Escobar, Luis Diaz, additional, Melgarejo, Donoband, additional, Cardozo, Analia, additional, Blanco, Anmylene, additional, Zelaya, Javier Adolfo, additional, Luraschi, Adriana, additional, Gonzalez, Victor Hugo Navia, additional, Almeida, Juan, additional, Conforto, Adriana, additional, Almeida, Marcele Schettini, additional, de Deus Silva, Leonardo, additional, Cuervo, Daissy Liliana Mora, additional, Zetola, Viviane Flumignan, additional, Martins, Rodrigo Targa, additional, Valler, Lenise, additional, Giacomini, Luidia Varrone, additional, Cardoso, Fabricio Buchdid, additional, Sahathevan, Ramesh, additional, Hair, Casey, additional, Hankey, Graeme, additional, Salazar, Daniel, additional, Lima, Fabricio Oliveira, additional, Mont’Alverne, Francisco, additional, Iman, Danny Moises Barrientos, additional, Magalhaes, Pedro, additional, Longo, Alexandre, additional, Rebello, Leticia, additional, Falup-Pecurariu, Cristian, additional, Mazya, Michael, additional, Wisniewska, Anna, additional, Fryze, Waldemar, additional, Kazmierski, Radoslaw, additional, Wisniewska, Malgorzata, additional, Horoch, Ewa, additional, Sienkiewicz-Jarosz, Halina, additional, Fudala, Malgorzata, additional, Rogoziewicz, Marcin, additional, Brola, Waldemar, additional, Sobolewski, Piotr, additional, Kaczorowski, Rafal, additional, Stepien, Adam, additional, Klivenyi, Peter, additional, Szapary, Laszlo, additional, van den Wijngaard, Ido, additional, Demchuk, Andrew, additional, Abraham, Michael, additional, Alvarado-Ortiz, Tony, additional, Kaushal, Ritesh, additional, Ortega-Gutierrez, Santiago, additional, Farooqui, Mudassir, additional, Bach, Ivo, additional, Badruddin, Aamir, additional, Barazangi, Nobl, additional, Nguyen, Claude, additional, Brereton, Charmaine, additional, Choi, Jae H., additional, Dharmadhikari, Sushrut, additional, Desai, Kinjal, additional, Doss, Vinodh, additional, Edgell, Randall, additional, Linares, Guillermo, additional, Frei, Donald, additional, Chaturvedi, Seemant, additional, Gandhi, Dheeraj, additional, Chaudhry, Saqib, additional, Choe, Hana, additional, Grigoryan, Mikayel, additional, Gupta, Rishi, additional, Helenius, Johanna, additional, Voetsch, Barbara, additional, Khwaja, Ayaz, additional, Khoury, Naim, additional, Kim, Benny S., additional, Kleindorfer, Dawn, additional, McDermott, Molly, additional, Koyfman, Feliks, additional, Leung, Lester, additional, Linfante, Italo, additional, Male, Shailesh, additional, Masoud, Hesham, additional, Min, Jiangyong, additional, Mittal, Manoj, additional, Multani, Sumeet, additional, Nahab, Fadi, additional, Nalleballe, Krishna, additional, Rahangdale, Rahul, additional, Rafael, Jose, additional, Rothstein, Aaron, additional, Ruland, Sean, additional, Sharma, Malveeka, additional, Singh, Abishek, additional, Starosciak, Amy, additional, Strasser, Sheryl, additional, Szeder, Viktor, additional, Teleb, Mohamed, additional, Tsai, Jenny, additional, Mohammaden, Mahmoud, additional, Pineda-Franks, Carissa, additional, Asyraf, Wan, additional, Nguyen, Trung QuocH, additional, Tarkanyi, Gabor, additional, Haussen, Diogo, additional, Balaguera, Oscar, additional, Vasquez, Alejandro Rodriguez, additional, and Nogueira, Raul, additional

Published
2021
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33. Thrombi in Acute Stroke Patients: Histopathological Analysis after Mechanical Thrombectomy.

Author

Salem, Haitham Hamdy, Ibrahim Elbassiouny, Ahmed Ali, Ibrahim Ali, Riham Ahmed, Atiah, Amr Saeed, and Mohamed, Sameh Medhat

Subjects
*INTERNAL carotid artery, *STROKE patients, *TREATMENT effectiveness, *HOSPITAL patients, *STROKE, *CEREBRAL angiography
Abstract

Background: The introduction of stent retrievers has made the complete extraction and histological analysis of human thrombi possible, although many studies have evaluated the retrieved thrombus by mechanical thrombectomy to assess its impact on success of acute stroke treatment, the results remain controversial, in this study we attempt to assess the impact of thrombus composition on mechanical recanalization, clinical outcome and stroke etiology. Objective: Study the histopathological composition of thrombi extracted from acute stroke patients through mechanical thrombectomy, and correlate the findings with the causes of stroke, the imaging findings as well as thrombectomy efficacy in terms of the number of recanalization maneuvers, retrieval resistance, and time to achieve successful reperfusion. Patients and Methods: The study was carried out at Ain Shams University hospitals to Patients presented to emergency department with large vessel occlusion and were candidate for mechanical thrombectomy. Participants were selected as sample sizes of 26 according to those meeting the inclusion Criteria for participant: patients with acute ischemic stroke with evidence of middle cerebral artery occlusion or internal carotid artery occlusion confirmed via cerebral angiography, Age ≥ 18 years old, NIHSS ≥ 6, Aspect score ≥ 6, time from onset to groin puncture is Within 24 hours, Patients for whom cerebral thrombus could be retrieved and collected during mechanical thrombectomy for histopathological analysis, and Agreement for written informed consent for participation or their nearest relatives in this study). Results: In our study, Erythrocyte-rich thrombi were present in 16 cases, while fibrin-rich thrombi were present in 5 cases. A cardioembolic etiology was significantly more prevalent among the patients with erythrocyte-rich thrombi than among those with fibrin/platelet and a P- value of<0.001. Puncture to final reperfusion time was significantly highest in cases with RBCrich with P-value of<0.001, and Number of passes needed to achieve reperfusion was significantly highest in cases with RBCrich with P-value 0.002. Conclusion: The current study showed Erythrocyte-rich thrombi were associated with a reduced number of recanalization maneuvers, shorter arrival-to-recanalization time interval, and more favorable clinical outcomes. This study also suggests that the histological composition of retrieved thrombi is significantly different between stroke subtypes. Cardioembolic thrombi have a higher percentage of erythrocytes and fewer fibrin/platelet than do non cardioembolic thrombi. [ABSTRACT FROM AUTHOR]

Published
2024
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34. Stent Retriever versus Contact Aspiration in Management of Acute Ischemic Stroke; Egyptian Experience.

Author

Amin Aref, Hany Mohammed, Ibrahim Elbassiouny, Ahmed Ali, Mohammed, Hossam Shokri, Othman El-Sudany, Ayman Hassan, Mahmoud Abushady, Eman Mones, and Abd El Monem, Eslam Ali Hamed

Subjects
*ISCHEMIC stroke, *THROMBECTOMY, *CEREBRAL infarction, *STROKE units, *STROKE patients
Abstract

Background: Mechanical thrombectomy (MT) has become the standard treatment in patients suffering from acute ischemic stroke (AIS) due to large vessel occlusion (LVO). It can be classified into thrombo-aspiration, stent-retrieval, and aspirationretriever combined technique. The evidence on the optimal therapy with acceptable outcomes of safety and efficacy is still limited. Therefore, we conducted this study to compare between stent retriever versus aspiration techniques in MT regarding procedural safety and incidence of complications. Methods: This prospective cohort study was conducted at Ain Shams University Hospitals, Egypt. One hundred patients admitted to stroke unit with anterior circulation AIS who met inclusion criteria for MT were recruited over three years from March 2020 to March 2023. The included patients were divided into two groups: group one included 50 patients treated with stent retriever and group two included 50 patients treated with contact aspiration thrombectomy. Results: The median (IQR) for age was 64 (52.5 - 71.5) years. 53 (53%) were males and 47 (47%) were females. No significant difference was found between the compared techniques regarding procedure time (p-value=0.551), time to recanalization (p-value =0.090), thrombolysis in cerebral infarction score (TICI) (pvalue =0.461. Conclusion: Among patients with ischemic stroke in anterior circulation undergoing MT, contact aspiration and stent retriever were comparable regarding successful recanalization rate. [ABSTRACT FROM AUTHOR]

Published
2024
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35. Effect of Heparin Reversal by Protamine Sulfate on the Outcome of Thrombolysis in Acute Ischemic Stroke after Percutaneous Coronary Intervention.

Author

Fawzy, Khaled Fayez, Aref, Hany Mohamed, Abd ElAziz, Azza Abd ElNasser, Ibrahim Elbassiouny, Ahmed Ali, Kenawy, Fatma Fathalla, and Fakhry Shehata, Emad Effat

Subjects
ISCHEMIC stroke, PROTAMINES, INTRACRANIAL hemorrhage, PERCUTANEOUS coronary intervention, PARTIAL thromboplastin time
Abstract

Background: Acute ischemic stroke (AIS) after percutaneous cardiac catheterization (PCI) is a known complication with incidence reports of ranges between 0.2% and 0.5%. It is associated with an in-hospital mortality rate of 20%, with markedly increased long-term mortality (1). Administration of Intravenous thrombolysis (IVT) is the recommended standard of care in acute ischemic stroke during the first 4.5 hours from stroke onset. However, current guidelines exclude intravenous thrombolysis in heparinized patients with partial thromboplastin time (PTT) greater than 40 seconds (2) Protamine is an efficient antidote known for the anticoagulant effect of heparin, and it can neutralize its effect within 5 minutes (3). Aim of the Work: To assess the safety of IVT after heparin reversal by protamine sulfate in ischemic Stroke patients After PCI. Patient and Method: The total number of patients who developed early IP stroke (within 4.5 hours from the end of PCI) was 42. All of them received loading antiplatelets before PCI. Results: out of 21 patients received IVT after heparin reversal by protamine, no patient had died, 2 cases had non symptomatic intracranial hemorrhage (ICH), with significant improvement in stroke parameters and shorter length of stay Conclusion: IVT following heparin reversal by protamine in appropriately selected AIS patients appears to be safe from a symptomatic ICH standpoint and may be beneficial. Extreme caution is warranted in applying these results to routine clinical practice. Rather, we suggest that thrombolysis may still be considered in AIS patients on therapeutic heparin who are not candidates for MT. [ABSTRACT FROM AUTHOR]

Published
2024
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36. Abstract P476: Safety and Efficacy of Balloon Mounted Drug-Eluting Stent in the Treatment of Symptomatic Intracranial Atherosclerotic Disease Multicenter International Experience

Author

Mohammaden, Mahmoud, primary, Nogueira, Raul G, additional, TEKLE, WONDWOSSEN, additional, siddiq, farhan, additional, Haussen, Diogo C, additional, Elbassiouny, Ahmed, additional, Aref, Hany, additional, Grigoryan, Mikayel, additional, Hanel, Ricardo, additional, Cortez, Gustavo, additional, Ortega, Santiago, additional, Zevallos, Cynthia, additional, Mudassir, Farooqui, additional, Maud, Alberto, additional, Sheth, Sunil, additional, Spiegel, Gary R, additional, Kan, Peter Tze Man, additional, Burkhardt, Jan-Karl, additional, and Hassan, Ameer E, additional

Published
2021
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39. In Memoriam of Professor Hany Aref: The Father, the Leader, and the Mentor.

Author

El Nahas, Nevine, El-Khawas, Hala, Elbassiouny, Ahmed, Shokri, Hossam, Hamid, Eman, Fathy, Mai, Abushady, Eman, Kenawy, Fatma, Dawood, Noha, Zaki, Amr, Bedros, Rady Y., and Roushdy, Tamer

Subjects
ISCHEMIC stroke, STROKE units, MENTORS, COLLEGE teachers
Abstract

Professor Hany M. Aref, MD, Ph.D., was a highly respected neurologist and leader in the field of stroke care in Egypt. He held numerous prestigious positions and was known for his dedication to improving stroke services and patient care. Prof. Aref's passion for his work was fueled by personal experience, as his mother had suffered a stroke when treatment options were limited in Egypt. He played a pivotal role in advocating for the implementation of advanced stroke treatments and establishing stroke units across the country. Tragically, Prof. Aref passed away before he could see the completion of his dream project, a state-of-the-art stroke unit at ASU Hospital. His legacy lives on through the impact he made on his students and colleagues, and his vision for transforming stroke care in Egypt. [Extracted from the article]

Published
2024
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40. A pilot study of the ticagrelor role in ischemic stroke secondary prevention.

Author

Zeinhom, Mohamed G., Aref, Hany M., El-khawas, Hala, Roushdy, Tamer M., Shokri, Hossam M., and elbassiouny, Ahmed

Subjects
STROKE, ISCHEMIC stroke, SECONDARY prevention, STROKE patients, TICAGRELOR, PLATELET aggregation inhibitors
Abstract

Introduction: Ticagrelor is one of the most recent antiplatelet drugs used to treat ischemic heart disease. Its efficacy may equal or exceed aspirin in improving clinical outcomes in patients with acute ischemic stroke who are ineligible for rt-PA. Aim of the Work: We aimed at evaluating the safety (as a primary endpoint) and efficacy (as a secondary endpoint) of a 180 mg loading dose of ticagrelor given within 9 h from the onset of first-ever ischemic stroke. Methods: We conducted an open-label, randomized prospective controlled clinical trial between May 2019 and September 2020 on patients who presented with their first-ever ischemic stroke and were recruited from the emergency department, of Kafr el-sheik University Hospitals, Egypt. Eligible patients randomly received aspirin or ticagrelor loading and maintenance doses. Treatment began within 9 h of stroke onset. Results: Aspirin was given to 84 patients; ticagrelor was given to 85. There was no significant difference between the 2 groups regarding the hemorrhagic and nonhemorrhagic complications. Patients who received ticagrelor had a better outcome regarding NIHSS improvement at 2 days and 1 week or discharge and a favorable mRS score after 1 week or discharge and at 90-day follow-up. Conclusion: Ticagrelor was noninferior to aspirin regarding safety profile. Compared with aspirin, ticagrelor had a better clinical outcome based on NIHSS and mRS in first-ever acute ischemic stroke patients who received it within 9 h from symptom onset, leading to a shorter hospital stay. [ABSTRACT FROM AUTHOR]

Published
2022
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44. Safety and efficacy of balloon-mounted stent in the treatment of symptomatic intracranial atherosclerotic disease: a multicenter experience

Author

Mohammaden, Mahmoud H, Nogueira, Raul G, Tekle, Wondwossen, Ortega-Gutierrez, Santiago, Farooqui, Mudassir, Zevallos, Cynthia B., Hanel, Ricardo A, Cortez, Gustavo M, Aghaebrahim, Amin, Starke, Robert M, Aref, Hany, Elbassiouny, Ahmed, Gamea, Ayman, Alaraj, Ali, Sadeh, Morteza, Grigoryan, Mikayel, Kuybu, Okkes, Haussen, Diogo C, Sheth, Sunil A, Maud, Alberto, Cordina, Steve M, Tanweer, Omar, Kan, Peter, Burkhardt, Jan-Karl, Grandhi, Ramesh, Siddiq, Farhan, and Hassan, Ameer E

Abstract

BackgroundRandomized clinical trials have failed to prove that the safety and efficacy of endovascular treatment for symptomatic intracranial atherosclerotic disease (ICAD) is better than that of medical management. A recent study using a self-expandable stent showed acceptable lower rates of periprocedural complications.ObjectiveTo study the safety and efficacy of a balloon-mounted stent (BMS) in the treatment of symptomatic ICAD.MethodsProspectively maintained databases from 15 neuroendovascular centers between 2010 and 2020 were reviewed. Patients were included if they had severe symptomatic intracranial stenosis in the target artery, medical management had failed, and they underwent intracranial stenting with BMS after 24 hours of the qualifying event. The primary outcome was the occurrence of stroke and mortality within 72 hours after the procedure. Secondary outcomes were the occurrence of stroke, transient ischemic attacks (TIAs), and mortality on long-term follow-up.ResultsA total of 232 patients were eligible for the analysis (mean age 62.8 years, 34.1% female). The intracranial stenotic lesions were located in the anterior circulation in 135 (58.2%) cases. Recurrent stroke was the qualifying event in 165 (71.1%) while recurrent TIA was identified in 67 (28.9%) cases. The median (IQR) time from the qualifying event to stenting was 5 (2–20.75) days. Strokes were reported in 13 (5.6%) patients within 72 hours of the procedure; 9 (3.9%) ischemic and 4 (1.7%) hemorrhagic, and mortality in 2 (0.9%) cases. Among 189 patients with median follow-up time 6 (3–14.5) months, 12 (6.3%) had TIA and 7 (3.7%) had strokes. Three patients (1.6%) died from causes not related to stroke.ConclusionOur study has shown that BMS may be a safe and effective treatment for medically refractory symptomatic ICAD. Additional prospective randomized clinical trials are warranted.

Published
2022
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45. The Whole is Greater than the Sum of the Parts: A Research Poster Project Provides an Integrative Framework for Learning Across Foundation Courses in Biology.

Author

Elbassiouny, Ahmed, DiSordi, Paolo, Guay, Sarah, Hamilton, Angela, King, Sarah, Brown, Jason, Molnar, Peter, Andrade, Maydianne C. B., Riggs, C. Dan, Stehlik, Ivana, and Ashok, Aarthi

Subjects
INFORMATION literacy, LEARNING communities, POSTERS, CONTINUING education, EDUCATIONAL change, SYNTHETIC biology, INTERORGANIZATIONAL relations
Abstract

The integration of ideas, defined as the process by which students organize and connect new knowledge for deeper understanding, is essential for lifelong learning. (Government of Canda, Employment and Social Development Canada, 2017; Rateau, Kaufman, & Cletzer, 2015). Integration across sub-disciplines in biology requires an understanding of organizational scales (molecular to ecosystems) and time frames (physiological to evolutionary), and how they inter-relate. The challenge lies in allowing students opportunity to integrate knowledge, given that sub-disciplines are taught in relative isolation through individual courses. To promote integration, we designed a poster assignment in which ~700 students in three foundation courses worked together (130 groups) to investigate empirical research in multiple subdisciplines. While a major goal was to enrich understanding by integrating knowledge, we also sought to develop transferable skills (e.g. teamwork, information literacy). Hence, this cross-course assignment provides benefits that exceed that of equivalent assignments in individual courses; we believe that the whole is greater than the sum of the parts. Assignment grades indicated that the majority (81%) of students successfully met or exceeded our expectations. This assignment lends support to the positive impact of learning communities, is easily adapted to other disciplines, and aligns with calls for educational reform advocating for curiosity-driven learning (American Association for the Advancement of Science, 2011; Bradforth et al., 2015). [ABSTRACT FROM AUTHOR]

Published
2020

47. Fish biogeography in the “Lost World” of the Guiana Shield: Phylogeography of the weakly electric knifefish <italic>Gymnotus carapo</italic> (Teleostei: Gymnotidae).

Author

Lehmberg, Emma S., Elbassiouny, Ahmed A., Bloom, Devin D., López‐Fernández, Hernán, Crampton, William G. R., and Lovejoy, Nathan R.

Subjects
*FISH ecology, *PHYLOGEOGRAPHY, *GYMNOTUS carapo, *HAPLOTYPES, *FISH phylogeny
Abstract

Abstract: Aim: The Guiana Shield region exhibits extraordinary topography that includes sheer, flat‐topped mountains (tepuis) atop an upland platform. Rivers of the eastern Pakaraima Mountains descend to Atlantic coastal lowlands, often traversing spectacular rapids and waterfalls. For fish species distributed in both uplands and lowlands, it is unclear whether these rapids and waterfalls present population or biogeographical boundaries. We sought to test this using the geographically widespread banded‐electric knifefish (Gymnotus carapo) as a model. Location: The Guiana Shield region of South America. Methods: We sampled 60 Gymnotus carapo specimens from the Guiana Shield region, and 75 G. carapo and closely related species from other parts of South America. We sequenced the mitochondrial cytochrome b gene and an intron from the nuclear S7 ribosomal protein gene, and used maximum likelihood and Bayesian tree‐building approaches to generate phylogenetic trees of haplotypes. Results: Haplotype sharing is minimal between populations separated by elevational barriers. We found evidence for two main haplotype clades in the Guiana Shield: one distributed in Atlantic coastal regions that includes most lowland samples, and one inland that includes most upland samples. Inland Guiana samples are more closely related to samples from the Amazon basin than to those of Atlantic coastal regions. A single sample from Tafelberg tepui in Suriname was most closely related to the Atlantic coastal lineages. Main conclusions: Riverine barriers that result from steep elevational gradients in the Guiana Shield inhibit gene flow between uplands and lowlands, even for a widely distributed species. Biogeographical relationships of Guiana Shield G. carapo are complex, with most upland lineages showing affinities to the Amazon basin, rather than to nearby lowland drainages of the Atlantic coast. [ABSTRACT FROM AUTHOR]

Published
2018
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48. Ecologically mediated differences in electric organ discharge drive evolution in a sodium channel gene in South American electric fishes

Author

Hauser, Frances E., Xiao, Dawn, Van Nynatten, Alexander, Brochu-De Luca, Kristen K., Rajakulendran, Thanara, Elbassiouny, Ahmed E., Sivanesan, Harunya, Sivananthan, Pradeega, Crampton, William G. R., and Lovejoy, Nathan R.

Abstract

Active electroreception—the ability to detect objects and communicate with conspecifics via the detection and generation of electric organ discharges (EODs)—has evolved convergently in several fish lineages. South American electric fishes (Gymnotiformes) are a highly species-rich group, possibly in part due to evolution of an electric organ (EO) that can produce diverse EODs. Neofunctionalization of a voltage-gated sodium channel gene accompanied the evolution of electrogenic tissue from muscle and resulted in a novel gene (scn4aa) uniquely expressed in the EO. Here, we investigate the link between variation in scn4aa and differences in EOD waveform. We combine gymnotiform scn4aa sequences encoding the C-terminus of the Nav1.4a protein, with biogeographic data and EOD recordings to test whether physiological transitions among EOD types accompany differential selection pressures on scn4aa. We found positive selection on scn4aa coincided with shifts in EOD types. Species that evolved in the absence of predators, which likely selected for reduced EOD complexity, exhibited increased scn4aa evolutionary rates. We model mutations in the protein that may underlie changes in protein function and discuss our findings in the context of gymnotiform signalling ecology. Together, this work sheds light on the selective forces underpinning major evolutionary transitions in electric signal production.

Published
2024
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