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2. Melatonin Levels in Children with Migraine

Author

Aydin, Tahir, Ayça, Senem, Yurdakul, Kamer, and Elevli, Murat

Subjects
Melatonin, Migraine, Sleep disorders, Sleep, Health
Abstract

Byline: Tahir. Aydin, Senem. Ayça, Kamer. Yurdakul, Murat. Elevli Background: Migraine is the most common primary headache in children. Neuromediators and deterioration in circadian rhythm and sleep disorders can play [...]

Published
2024

3. Diagnostic Value of Pentraxin-3 in COVID-19 Pediatric Patients.

Author

Topçu, Didem Öcal, Şahin, Kamil, Elevli, Murat, Yılmaz, İbrahim, and Akkoç, Gülşen

Subjects
LYMPHOCYTE count, LEUKOCYTE count, CHILD patients, POLYMERASE chain reaction, PLATELET count
Abstract

Copyright of Bagcilar Medical Bulletin / Bağcılar Tıp Bülteni is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2024
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6. SARS-CoV-2 seropositivity among pediatric health care personnel just after the first peak of pandemic: A nationwide surveillance

Author

Oygar, Pembe Derin, Büyükçam, Ayşe, Bal, Zümrüt Şahbudak, Dalgıç, Nazan, Bozdemir, Şefika Elmas, Karbuz, Adem, Çetin, Benhur Şirvan, Kara, Yalçın, Çetin, Ceren, Hatipoğlu, Nevin, Uygun, Hatice, Aygün, Fatma Deniz, Törün, Selda Hançerli, Okur, Dicle Şener, Çiftdoğan, Dilek Yılmaz, Kara, Tuğçe Tural, Yahşi, Aysun, Özer, Arife, Demir, Sevliya Öcal, Akkoç, Gülşen, Turan, Cansu, Salı, Enes, Şen, Semra, Erdeniz, Emine Hafize, Kara, Soner Sertan, Emiroğlu, Melike, Erat, Tuğba, Aktürk, Hacer, Gürlevik, Sibel Laçinel, Sütçü, Murat, Aydın, Zeynep Gökçe Gayretli, Atikan, Başak Yıldız, Yeşil, Edanur, Güner, Gizem, Çelebi, Emel, Efe, Kadir, İşançlı, Didem Kızmaz, Durmuş, Habibe Selver, Tekeli, Seher, Karaaslan, Ayşe, Bülbül, Lida, Almış, Habip, Kaba, Özge, Keleş, Yıldız Ekemen, Yazıcıoğlu, Bahadır, Oğuz, Şerife Bahtiyar, Ovalı, Hüsnü Fahri, Doğan, Hazal Helin, Çelebi, Solmaz, Çakır, Deniz, Karasulu, Burcugül, Alkan, Gülsüm, Yenidoğan, İrem, Gül, Doruk, Küçükalioğlu, Burcu Parıltan, Avcu, Gülhadiye, Kukul, Musa Gürel, Bilen, Melis, Yaşar, Belma, Üstün, Tuğba, Kılıç, Ömer, Akın, Yasemin, Cebeci, Sinem Oral, Bucak, Ibrahim Hakan, Yanartaş, Mehpare Sarı, Şahin, Aslıhan, Arslanoğlu, Sertaç, Elevli, Murat, Çoban, Rabia, Öz, Şadiye Kübra Tüter, Hatipoğlu, Halil, Erkum, İlyas Tolga, Turgut, Mehmet, Demirbuğa, Asuman, Özçelik, Taha, Çiftçi, Diclehan, Sarı, Emine Ergül, Akkuş, Gökhan, Hatipoğlu, Sadık Sami, Dinleyici, Ener Çağrı, Hacımustafaoğlu, Mustafa, Özkınay, Ferda, Kurugöl, Zafer, Cengiz, Ali Bülent, Somer, Ayper, Tezer, Hasan, and Kara, Ateş

Published
2021
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9. Melatonin Levels in Children with Migraine.

Author

Aydın, Tahir, Ayça, Senem, Yurdakul, Kamer, and Elevli, Murat

Subjects
MIGRAINE, CHRONOBIOLOGY disorders, PRIMARY headache disorders, MELATONIN, ENZYME-linked immunosorbent assay
Abstract

Background: Migraine is the most common primary headache in children. Neuromediators and deterioration in circadian rhythm and sleep disorders can play a role in the etiology of migraines. Aim: To determine the serum melatonin levels of children with migraine and the relationship between melatonin and childhood migraine. Materials and Methods: Thirty-five children aged between 10 and 18 years with migraine as the case group and 35 healthy children of similar age and sex as the control group were included in the study. Venous blood samples were taken at 09.00 AM and melatonin analysis was performed using enzyme-linked immunosorbent assay (ELISA). Results: The mean serum melatonin levels of the case group and control group were found to be 300.1 ± 67.3 pg/mL and 314.9 ± 64.0 pg/mL, respectively. There was no statistically significant difference between the groups (P = 0.351). Comparison of the melatonin levels in the case group according to the clinical characteristics was not significantly different. Conclusion: An association between sleep and migraine is predictable, but its pathophysiology is not yet known. Etiological studies continue and the relationship between melatonin and migraine remains unclear. [ABSTRACT FROM AUTHOR]

Published
2024
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10. SARS-COV-2 infections in children: The role of fibrinogen in predicting diagnosis and severity: A retrospective cohort study.

Author

Akkoc, Gulsen, Ağbaş, Ayşe, Göksu, Eralp, Beyaz, Sevde, Yıldız, Funda, Bayramoğlu, Elvan, Yolcu, Canan, Ayça, Senem, Dolu, Nurcihan Çalışkan, Şahin, Kamil, Koldaş, Macit, and Elevli, Murat

Subjects
SARS-CoV-2, CORONAVIRUS diseases, COVID-19, FIBRINOGEN
Abstract

Background. Evaluating predictors of coronavirus disease 2019 (COVID-19) and severity among children may help clinicians manage the high rate of hospital admissions for suspected cases. Objectives. This study aimed to evaluate the demographic, clinical and laboratory characteristics of children during the pandemic, and determine the predictors of COVID-19 and moderate-to-severe disease. Materials and methods. This retrospective cohort study included all consecutive COVID-19 cases in patients aged <18 years who presented to the Pediatric Emergency Department at Haseki Training and Research Hospital (Istanbul, Turkey) between March 15 and May 1, 2020, and underwent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) polymerase chain reaction (PCR) analysis of oro-nasopharyngeal swabs (n = 1137). Results. The frequency of SARS-CoV-2 PCR positivity was 28.6%. The COVID-19 (+) group presented with sore throat, headache and myalgia significantly more frequently than the COVID-19 (-) group. Multivariate logistic regression models showed independent predictors of SARS-CoV-2 positivity as follows: age, contact history, lymphocyte count <1500/mm3, and neutrophil count <4000/mm3. In addition, higher age, neutrophil count and fibrinogen levels were independent predictors of severity. The diagnostic cutoff value for fibrinogen (370.5 mg/dL) had a sensitivity of 53.12, specificity of 83.95, positive predictive value (PPV) of 39.53, and negative predictive value (NPV) of 90.07 for predicting severity. Conclusions. Symptomatology, whether alone or in combination with other approaches, may be an appropriate strategy to guide the diagnosis and management of COVID-19. [ABSTRACT FROM AUTHOR]

Published
2024
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11. SARS-COV-2 infections in children: The role of fibrinogen in predicting diagnosis and severity: A retrospective cohort study

Author

Akkoc, Gulsen, primary, Ağbaş, Ayşe, additional, Göksu, Eralp, additional, Beyaz, Sevde, additional, Yıldız, Funda, additional, Bayramoğlu, Elvan, additional, Yolcu, Canan, additional, Ayça, Senem, additional, Çalışkan Dolu, Nurcihan, additional, Şahin, Kamil, additional, Koldaş, Macit, additional, and Elevli, Murat, additional

Published
2023
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20. Demographic and Clinical Characteristics of COVID-19 in Children and the Effect of Household Tobacco Smoke Exposure on COVID-19

Author

Akkoç, Gülşen, Akgün, Özlem, Kızılırmak, Cevher, Yıldız, Funda, Duru, Hatice Nilgün Selçuk, and Elevli, Murat

Subjects
coronavirus disease 2019, children, Coronavirus disease 2019 (COVID-19), business.industry, Environmental health, Tobacco smoke exposure, COVID-19, Medicine, Original Article, business, Environmental tobacco smoke exposure
Abstract

Objective: Environmental tobacco smoke (ETS) exposure is associated with many diseases, including lower respiratory tract infections, in pediatric age groups. In this study, we aimed to assess the effect of household ETS exposure on symptom frequency and clinical severity in children and adolescents with COVID-19. Materials and Methods: This retrospective study included pediatric cases (

Published
2021

21. Evaluation of vaccination status of health care workers for recommended vaccines and their acceptance of SARS-CoV-2 vaccines

Author

Oygar, Pembe Derin, primary, Büyükçam, Ayşe, additional, Sahbudak Bal, Zumrut, additional, Dalgıç, Nazan, additional, Bozdemir, Şefika Elmas, additional, Karbuz, Adem, additional, Çetin, Benhur Şirvan, additional, Kara, Yalçın, additional, Çetin, Ceren, additional, Hatipoğlu, Nevin, additional, Uygun, Hatice, additional, Aygün, Fatma Deniz, additional, Hançerli Törün, Selda, additional, Şener Okur, Dicle, additional, Yılmaz Çiftdoğan, Dilek, additional, Tural Kara, Tuğçe, additional, Yahşi, Aysun, additional, Özer, Arife, additional, Öcal Demir, Sevliya, additional, Akkoç, Gülşen, additional, Turan, Cansu, additional, Salı, Enes, additional, Şen, Semra, additional, Erdeniz, Emine Hafize, additional, Kara, Soner Sertan, additional, Emiroğlu, Melike, additional, Erat, Tuğba, additional, Aktürk, Hacer, additional, Laçinel Gürlevik, Sibel, additional, Sütçü, Murat, additional, Gayretli Aydın, Zeynep Gökçe, additional, Yıldız Atikan, Başak, additional, Yeşil, Edanur, additional, Güner Özenen, Gizem, additional, Çelebi, Emel, additional, Efe, Kadir, additional, Kizmaz isancli, Didem, additional, Selver Durmuş, Habibe, additional, Tekeli, Seher, additional, Karaaslan, Ayşe, additional, Bülbül, Lida, additional, Almış, Habip, additional, Kaba, Özge, additional, Ekemen Keleş, Yıldız, additional, Yazıcıoğlu, Bahadır, additional, Bahtiyar Oğuz, Serife, additional, Ovalı, Hüsnü Fahri, additional, Doğan, Hazal Helin, additional, Çelebi, Solmaz, additional, Çakir, Deniz, additional, Karasulu, Burcugül, additional, Alkan, Gülsüm, additional, Yenidoğan, İrem, additional, Gül, Doruk, additional, Parıltan Kücükalioğlu, Burcu, additional, Avcu, Gülhadiye, additional, Kukul, Musa Gürel, additional, Bilen, Melis, additional, Yaşar, Belma, additional, Üstün, Tuğba, additional, Kılıç, Ömer, additional, Akın, Yasemin, additional, Oral Cebeci, Sinem, additional, Bucak, İbrahim Hakan, additional, Sarı Yanartaş, Mehpare, additional, Şahin, Aslıhan, additional, Arslanoglu, Sertaç, additional, Elevli, Murat, additional, Çoban, Rabia, additional, Tuter Öz, Sadiye Kübra, additional, Hatipoğlu, Halil, additional, Erkum, İlyas Tolga, additional, Turgut, Mehmet, additional, Demirbuğa, Asuman, additional, Özçelik, Taha, additional, Çiftçi, Diclehan, additional, Sarı, Emine Ergül, additional, Akkuş, Gökhan, additional, Hatipoğlu, Sadık Sami, additional, Dinleyici, Ener Cağrı, additional, Hacimustafaoğlu, Mustafa, additional, Özkınay, Ferda, additional, Kurugöl, Zafer, additional, Cengiz, Ali Bulent, additional, Somer, Ayper, additional, Tezer, Hasan, additional, and Kara, Ateş, additional

Published
2022
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25. Ev İçi Aktif Tüberküloz ile Temas Sonrası Çocuklarda Tüberküloz Hastalığı Gelişme Riskinin Değerlendirilmesi

Author

OKAY, Berker, AKKOÇ, Gülşen, ELEVLİ, Murat, and ŞAHİN, Kamil

Subjects
Health Care Sciences and Services, Çocuk,Ev içi temas,Koruyucu tedavi,Tüberküloz, General Medicine, Sağlık Bilimleri ve Hizmetleri
Abstract

Amaç: Çocuklarda tüberkülozun erken ve doğru tanısı tüberküloz kontrolünde ve tedavisinde oldukça önemlidir. Bu çalışma ev içi aktif tüberküloz tanılı birey ile temas sonrası tüberküloz gelişme riskinin ve tanıya yönelik tetkiklerin değerlendirmesi amaçlanmıştır.Gereç ve Yöntem: Bu çalışmada 1 Mayıs 2019-2 Ocak 2020 tarihleri arasında hastanemiz çocuk enfeksiyon polikliniğine başvuran ev içi aktif tüberkülozlu birey ile teması olan 0-18 yaş arası ve tüberküloz proflaksisi almayan hastalar, retrospektif olarak incelendi. Olgulardan istenmiş olan kan tahlilleri, akciğer görüntülemesi ve 3 gün sabahları alınan mide açlık suyunda aside dirençli bakteri boyanma, mikobakteri kültürü, tüberküloz PCR tetkiklerine hastane bilgi yönetim sisteminden bakılarak formlara not edildi.Bulgular: Çalışmaya katılan çocuklar yaş, cinsiyet, şikâyet, indeks vakanın kimliği, BCG aşı skarının varlığı, ev içi temas süresi, PPD boyutu, laboratuvar sonuçları, akciğer görüntülemesi açısından incelendi. Tüberküloz hastalığı ve latent tüberküloz enfeksiyonu tedavisi alan çocuklar arasında yaş, indeks vakanın kimliği, akciğer görüntülemesi, C reaktif protein, lökosit, nötrofil değerleri ve PPD boyutu açısından istatistiksel olarak anlamlı fark saptandı (p

Published
2022

30. SARS-CoV-2 seropositivity among pediatric health care personnel after the first peak of the pandemic: nationwide surveillance in Turkey

Author

Oygar, Pembe Derin, primary, Büyükçam, Ayşe, additional, Bal, Zümrüt Şahbudak, additional, Dalgıç, Nazan, additional, Bozdemir, Şefika Elmas, additional, Karbuz, Adem, additional, Çetin, Benhur Şirvan, additional, Kara, Yalçın, additional, Çetin, Ceren, additional, Hatipoğlu, Nevin, additional, Uygun, Hatice, additional, Aygün, Fatma Deniz, additional, Törün, Selda Hançerli, additional, Okur, Dicle Şener, additional, Çiftdoğan, Dilek Yılmaz, additional, Kara, Tuğçe Tural, additional, Yahşi, Aysun, additional, Özer, Arife, additional, Demir, Sevliya Öcal, additional, Akkoç, Gülşen, additional, Turan, Cansu, additional, Salı, Enes, additional, Şen, Semra, additional, Erdeniz, Emine Hafize, additional, Kara, Soner Sertan, additional, Emiroğlu, Melike, additional, Erat, Tuğba, additional, Aktürk, Hacer, additional, Gürlevik, Sibel Laçinel, additional, Sütçü, Murat, additional, Aydın, Zeynep Gökçe Gayretli, additional, Atikan, Başak Yıldız, additional, Yeşil, Edanur, additional, Güner, Gizem, additional, Çelebi, Emel, additional, Efe, Kadir, additional, İşançlı, Didem Kızmaz, additional, Durmuş, Habibe Selver, additional, Tekeli, Seher, additional, Karaaslan, Ayşe, additional, Bülbül, Lida, additional, Almış, Habip, additional, Kaba, Özge, additional, Keleş, Yıldız Ekemen, additional, Yazıcıoğlu, Bahadır, additional, Oğuz, Şerife Bahtiyar, additional, Ovalı, Hüsnü Fahri, additional, Doğan, Hazal Helin, additional, Çelebi, Solmaz, additional, Çakır, Deniz, additional, Karasulu, Burcugül, additional, Alkan, Gülsüm, additional, Yenidoğan, İrem, additional, Gül, Doruk, additional, Küçükalioğlu, Burcu Parıltan, additional, Avcu, Gülhadiye, additional, Kukul, Musa Gürel, additional, Bilen, Melis, additional, Yaşar, Belma, additional, Üstün, Tuğba, additional, Kılıç, Ömer, additional, Akın, Yasemin, additional, Cebeci, Sinem Oral, additional, Bucak, Ibrahim Hakan, additional, Yanartaş, Mehpare Sarı, additional, Şahin, Aslıhan, additional, Arslanoğlu, Sertaç, additional, Elevli, Murat, additional, Çoban, Rabia, additional, Öz, Şadiye Kübra Tüter, additional, Hatipoğlu, Halil, additional, Erkum, İlyas Tolga, additional, Turgut, Mehmet, additional, Demirbuğa, Asuman, additional, Özçelik, Taha, additional, Çiftçi, Diclehan, additional, Sarı, Emine Ergül, additional, Akkuş, Gökhan, additional, Hatipoğlu, Sadık Sami, additional, Dinleyici, Ener Çağrı, additional, Hacımustafaoğlu, Mustafa, additional, Özkınay, Ferda, additional, Kurugöl, Zafer, additional, Cengiz, Ali Bülent, additional, Somer, Ayper, additional, Tezer, Hasan, additional, and Kara, Ateş, additional

Published
2021
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31. SARS-CoV-2 seropositivity among pediatric health care personnel just after the first peak of pandemic: A nationwide surveillance

Author

Gürlevik, Sibel Laçinel, Kaba, Özge, Aktürk, Hacer, Erkum, İlyas Tolga, Turgut, Mehmet, Demirbuğa, Asuman, Keleş, Yıldız Ekemen, Yazıcıoğlu, Bahadır, Hacımustafaoğlu, Mustafa, Dinleyici, Ener Çağrı, Erat, Tuğba, Emiroğlu, Melike, Üstün, Tuğba, Kara, Soner Sertan, Doğan, Hazal Helin, Erdeniz, Emine Hafize, İşançlı, Didem Kızmaz, Yanartaş, Mehpare Sarı, Efe, Kadir, Çetin, Ceren, Dalgıç, Nazan, Büyükçam, Ayşe, Oygar, Pembe Derin, Yaşar, Belma, Ovalı, Hüsnü Fahri, Özçelik, Taha, Bilen, Melis, Bal, Zümrüt Şahbudak, Kukul, Musa Gürel, Özkınay, Ferda, Küçükalioğlu, Burcu Parıltan, Gül, Doruk, Avcu, Gülhadiye, Bozdemir, Şefika Elmas, Yenidoğan, İrem, Alkan, Gülsüm, Çiftçi, Diclehan, Şen, Semra, Kılıç, Ömer, Karbuz, Adem, Güner, Gizem, Yeşil, Edanur, Tezer, Hasan, Salı, Enes, Karasulu, Burcugül, Atikan, Başak Yıldız, Turan, Cansu, Akkoç, Gülşen, Demir, Sevliya Öcal, Oğuz, Şerife Bahtiyar, Çelebi, Solmaz, Özer, Arife, Yahşi, Aysun, Kara, Tuğçe Tural, Çiftdoğan, Dilek Yılmaz, Okur, Dicle Şener, Törün, Selda Hançerli, Akkuş, Gökhan, Hatipoğlu, Sadık Sami, Sarı, Emine Ergül, Arslanoğlu, Sertaç, Şahin, Aslıhan, Öz, Şadiye Kübra Tüter, Çelebi, Emel, Aydın, Zeynep Gökçe Gayretli, Hatipoğlu, Halil, Sütçü, Murat, Durmuş, Habibe Selver, Tekeli, Seher, Karaaslan, Ayşe, Bülbül, Lida, Almış, Habip, Cebeci, Sinem Oral, Akın, Yasemin, Kurugöl, Zafer, Aygün, Fatma Deniz, Kara, Ateş, Somer, Ayper, Cengiz, Ali Bülent, Uygun, Hatice, Çoban, Rabia, Elevli, Murat, Çakır, Deniz, Hatipoğlu, Nevin, Kara, Yalçın, Bucak, Ibrahim Hakan, and Çetin, BENHUR ŞİRVAN

Subjects
COVID-1, personnel protective equipment use, Turkey, SARS-CoV-2, Health Personnel, serology, COVID-19, Antibodies, Viral, Article, Seroepidemiologic Studies, Humans, Child, Delivery of Health Care, Pandemics, SARS Co-V-2, healthcare personnel
Abstract

Understanding SARS-CoV-2 seroprevalence among health care personnel is important to explore risk factors for transmission, develop elimination strategies and form a view on the necessity and frequency of surveillance in the future.We enrolled 4927 health care personnel working in pediatric units at 32 hospitals from 7 different regions of Turkey in a study to determine SARS Co-V-2 seroprevalence after the first peak of the COVID-19 pandemic. A point of care serologic lateral flow rapid test kit for immunoglobulin (Ig)M/IgG was used. Seroprevalence and its association with demographic characteristics and possible risk factors were analyzed.SARS-CoV-2 seropositivity prevalence in health care personnel tested was 6.1%. Seropositivity was more common among those who did not universally wear protective masks (10.6% vs 6.1%). Having a COVID-19-positive co-worker increased the likelihood of infection. The least and the most experienced personnel were more likely to be infected. Most of the seropositive health care personnel (68.0%) did not suspect that they had previously had COVID-19.Health surveillance for health care personnel involving routine point-of-care nucleic acid testing and monitoring personal protective equipment adherence are suggested as important strategies to protect health care personnel from COVID-19 and reduce nosocomial SARS-CoV-2 transmission.

Published
2021

32. Subclinical atherosclerosis and ambulatory blood pressure in children with metabolic syndrome

Author

Civilibal, Mahmut, Duru, Nilgun Selcuk, and Elevli, Murat

Subjects
Metabolic syndrome X -- Research -- Risk factors -- Diagnosis -- Care and treatment -- Patient outcomes, Atherosclerosis -- Research -- Risk factors -- Development and progression, Health
Abstract

Background The metabolic syndrome (MS) has reached epidemic proportions worldwide. This syndrome is associated with cardiovascular risk factors, including functional and structural cardiac and vascular changes. The aim of our study was to evaluate subclinical atherosclerosis and its associated risk factors in children with MS. Methods The study cohort comprised 52 children with MS and 38 age- and sex-matched healthy children. The diagnosis of MS was made according to criteria adopted by the World Health Organization. Blood pressure based on 24-h ambulatory blood pressure monitoring (ABPM), carotid intimamedia thickness (cIMT), carotid distensibility coefficient (DC) and flow-mediated endothelium-dependent dilation (EDD) were assessed in all children. Results We found a significantly higher cIMT in children with MS than in healthy children, but carotid DC and flowmediated EDD were lower in the former. Multivariate analysis revealed that a higher cIMT was independently associated with a higher nighttime systolic blood pressure (SBP) and lower high-density lipoprotein-cholesterol ([beta] =0.386, p=0.011 and [beta] =0.248, p=0.042, respectively). Also, higher nighttime SBP remained an independent predictor of lower DC ([beta] =0.495, p=0.009), and higher 24-h SBP was the only independent predictor for a lower EDD ([beta] =0.532, p=0.004). Conclusions Atherosclerotic vascular changes were common among our pediatric patients with MS and easily determined by high-resolution ultrasound imaging. In particular, subclinical atherosclerosis was clearly associated with nocturnal or 24-h systolic hypertension as measured by ABPM. We therefore recommend that subclinical vascular changes and AMBP measurements should be used as diagnostic markers to predict atherosclerotic risks in this pediatric patient group. Keywords Ambulatory blood pressure monitoring Carotid intima media thickness * Carotid distensibility * Childhood * Endothelium-dependent dilatation * Metabolic syndrome, Introduction Metabolic syndrome (MS) is a disorder of energy utilization and storage, defined as a combination of abdominal obesity, elevated blood pressure, dyslipidemia, and insulin resistance or impaired glucose tolerance. [...]

Published
2014
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35. Kidney Involvement in Pediatric COVID-19 Cases: A Single-Center Experience.

Author

Ağbaş, Ayşe, Akkoç, Gülşen, Kızılırmak, Cevher, Dolu, Nurcihan Çalışkan, Bayramoğlu, Elvan, and Elevli, Murat

Subjects
COVID-19, CONFIDENCE intervals, RETROSPECTIVE studies, RISK assessment, SEVERITY of illness index, PROTEINURIA, DESCRIPTIVE statistics, HEMATURIA, LOGISTIC regression analysis, ODDS ratio, ACUTE kidney failure, CREATININE, DISEASE risk factors, CHILDREN, ADOLESCENCE
Abstract

Objective: The kidney is the second most commonly affected organ by severe acute respiratory syndrome coronavirus-2, characterized by hematuria, proteinuria, and acute kidney injury. There are few studies describing renal involvement in pediatric cases. Materials and Methods: This retrospective study evaluated the prevalence of hematuria, proteinuria, and acute kidney injury in severe acute respiratory syndrome coronavirus-2-positive pediatric cases (1-18 years old) who visited emergency department between March and November 2020. Patients with urinary tract infections were excluded. An age-specific upper limit of reference interval was used to define "elevated serum creatinine" (greater than upper limit of reference interval) and acute kidney injury (>1.5 times upper limit of reference interval). Results: A total of 228 patients were evaluated, median age was 12.7 years (interquartile range: 7.5; 16.1), and 51.3% were male. The prevalence of asymptomatic, mild, and moderate-to-severe disease was 12.7% (29/228), 77.2% (176/228), and 10.1% (23/228), respectively. The prevalence of hematuria, proteinuria, and elevated serum creatinine was 15.8% (36/228), 6% (14/228), and 3% (7/228), respectively. Kidney involvement (i.e., at least 1 of these findings) was 23.2% (53/228) and significantly higher in the moderate-to-severe disease (43.5%). None of the patients met the acute kidney injury criterion. In logistic regression analysis, female sex (odds ratio: 1.97, 95 CI%: 1.03; 3.70, P = .040) and fever (odds ratio: 2.28, 95% CI: 1.19; 4.36, P = .012) were independent predictors of kidney involvement. Three patients demonstrated a kidney presentation (macroscopic hematuria) on admission, and another patient was diagnosed with C3 glomerulonephritis during hospitalization. Conclusion: Kidney involvement was found about in 1 quarter of children with coronavirus disease 2019. Awareness and recognition of kidney involvement and follow-up are important in the management. [ABSTRACT FROM AUTHOR]

Published
2022
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38. Evaluation of Clinical and Epidemiological Features of Patients Receiving High-Flow Nasal Cannula Oxygen Therapy in the Pediatric Intensive Care Unit

Author

BÜYÜKŞEN, Osman, BAYRAKTAR, Süleyman, and ELEVLİ, Murat

Subjects
çocuk,çocuk yoğun bakım ünitesi,solunum yetersizliği,oksijen tedavisi, child,Pediatric intensive care unit,Respiratory failure,oxygen therapy, Medicine, Tıp
Abstract

Amaç: Akut solunum yetmezliğinde solunum desteği yöntemlerinden biri, giderek kullanım sıklığı artan yüksek akımlı nazal kanül oksijen tedavisidir (YANKOT). Bu çalışmada, solunum yetmezliği nedeniyle çocuk yoğun bakım ünitesine yatırılan ve YANKOT uygulanan hastaların retrospektif olarak değerlendirilmesi amaçlandı. Araçlar ve Yöntem: Çalışma retrospektif olarak, Ocak 2015- Aralık 2017 tarihleri arasında çocuk yoğun bakım ünitesinde yatan ve YANKOT uygulanmış 104 hasta alınarak yapıldı. Bulgular: Çalışmaya katılan hastaların yaşlarının medyan değeri 5 ay olarak saptandı. En sık yatış endikasyonu %97.1 oranında alt hava yolu hastalığıydı ve hastaların %52.9’unda tip 1 solunum yetmezliği saptandı. Çocuk yoğun bakımdaki yatış süresi medyan değeri 7 gün iken, YANKOT uygulama süresi medyan değeri 48 saat olarak saptandı. YANKOT alırken entübe olan hastalarda (%28.8) kronik hastalık ve kronik akciğer hastalığı entübe olmayanlara göre belirgin olarak yüksekti (p=0.001, p=0.033, sırasıyla). Hastalarda komplikasyon olarak %8.7’sinde nazal bölgede cilt hasarı, %1.9’unda pnömotoraks geliştiği saptandı. Çocuk yoğun bakım ünitesine yatıp YANKOT alırken ölen hastalarda kronik hastalık ve konjenital kalp hastalığı oran-ları hayatta kalan hastalara göre belirgin olarak yüksekti (p=0.043, p=0.003, sırasıyla).Sonuç: Son yıllarda çocuklarda solunum yetmezliği tedavisinde kullanılmaya başlanan YANKOT’un sonuçları genellikle yüz güldürücüdür. Bununla birlikte bu yeni yöntemde komplikasyonların gelişebilmesi nedeniyle uygulama süresince yakın izlem gerekmektedir., Purpose: One of the respiratory supports in acute respiratory failure (ARF) is high-flow nasal cannula (HFNC) oxygen therapy, which is being increasingly used in this study. We aimed to evaluate the patients with ARF who received HFNC oxygen therapy in the pediatric intensive care unit (ICU).Materials and Methods: The study was done retrospectively in 104 patients who were admitted to the pediatric ICU and received HFNC oxygen therapy between January 2015 and December 2017. Results: The median age of the patients participating in the study was 5 months. The most common cause of hospitalization was lower respiratory disease (97.1%), and 52.9% of the patients had type 1 respiratory failure. The median length of stay in the pediatric ICU was 7 days, while the median duration of HFNC oxygen therapy was 48 hours. In patients who were intubated during HFNC oxygen therapy (28.8%), the proportions of having a chronic disease and chronic lung disease were significantly higher than those who were not intubated (p=0.001, p=0.033, respectively). In terms of complications, nasal skin damage (8.7%) and pneumothorax (1.9%) were developed. The proportions of chronic diseases and congenital heart disease of the patients who were admitted to pediatric ICU and died after HFNC oxygen therapy were significantly higher than the survivors (p=0.043, p=0.003, respectively).Conclusion: The results of HFNC oxygen therapy, which is being increasingly used in the treatment of respiratory failure in children, are generally satisfactory. However, due to possible complications, close monitoring is required during the application.

Published
2021

39. Epidemiological, clinical, and laboratory features of children with COVID-19 in Turkey

Author

Aktürk, Hacer; Khalilova, Fidan; Çelikyurt, Aydın, Karbuz, Adem; Akkoç, Gülşen; Bedir Demirdağ, Tuğba; Yılmaz Çiftdoğan, Dilek; Özer, Arife; Çakır, Deniz; Hançerli Törün, Selda; Kepenekli, Eda; Erat, Tuğba; Dalgıç, Nazan; İlbay, Sare; Karaaslan, Ayşe; Erdeniz, Emine H.; Aygün, F. Deniz; Bozdemir, S. Elmas; Hatipoğlu, Nevin; Emiroğlu, Melike; Şahbudak Bal, Zümrüt; Çiftçi, Ergin; Bayhan, Gülsüm İclal; Gayretli Aydın, Zeynep Gökçe; Öcal Demir, Sevliya; Kılıç, Ömer; Hacımustafaoğlu, Mustafa; Şener Okur, Dicle; Şen, Semra; Yahşi, Aysun; Çetin, Benhur; Sütçü, Murat; Kara, Manolya; Uygun, Hatice; Tural Kara, Tuğçe; Korukluoğlu, Gülay; Akgün, Özlem; Üstündağ, Gülnihan; Demir Mis, Mevsim; Salı, Enes; Kaba, Özge; Yakut, Nurhayat; Kılıç, Orhan; Kanık, M. Kemal; Çetin, Ceren; Dursun, Adem; Çiçek, Muharrem; Koçkuzu, Esra; Şevketoğlu, Esra; Alkan, Gülsüm; Güner Özenen, Gizem; İnce, Erdal; Baydar, Zekiye; Özkaya, Ahmet Kağan; Ovalı, Hüsnü Fahri; Tekeli, Seher; Çelebi, Solmaz; Çubukçu, Birgül; Bal, Alkan; Köse, Mehmet; Hatipoğlu, Halil Uğur; Dalkıran, Tahir; Turgut, Mehmet; Başak Altaş, Ayşe; Selçuk Duru, Hatice Nilgün; Aksay, Ahu; Sağlam, Sevcan; Sarı Yanartaş, Mehpare; Ergenç, Zeynep; Akın, Yasemin; Düzenli Kar, Yeter; Şahin, Sabit; Tüter Öz, Şadiye Kübra; Bilen, Nimet Melis; Özdemir, Halil; Şenoglu, Mine Çiğdem; Parıltan Küçükalioğlu, Burcu; Besli, Gülser Esen; Kara, Yalçın; Turan, Cansu; Selbest Demirtaş, Burcu; Coşgun, Yasemin; Elevli, Murat; Şahin, Aslıhan; Bahtiyar Oğuz, Şerife; Somer, Ayper; Karadağ, Bülent; Demirhan, Recep; Türk Dağı, Hatice; Kurugöl, Zafer; Taşkın, Esra Çakmak; Şahiner, Ayşegül; Yeşil, Edanur; Ekemen Keleş, Yıldız; Sarıkaya, Remzi; Erdem Eralp, Ela; Özkınay, Ferda; Konca, Hatice Kübra; Yılmaz, Songül; Gökdemir, Yasemin; Arga, Gül; Özen, Seval; Çoksüer, Fevziye; Vatansever, Göksel; Tezer, Hasan; Kara, Ateş, Aktürk, Hacer; Khalilova, Fidan; Çelikyurt, Aydın, and Karbuz, Adem; Akkoç, Gülşen; Bedir Demirdağ, Tuğba; Yılmaz Çiftdoğan, Dilek; Özer, Arife; Çakır, Deniz; Hançerli Törün, Selda; Kepenekli, Eda; Erat, Tuğba; Dalgıç, Nazan; İlbay, Sare; Karaaslan, Ayşe; Erdeniz, Emine H.; Aygün, F. Deniz; Bozdemir, S. Elmas; Hatipoğlu, Nevin; Emiroğlu, Melike; Şahbudak Bal, Zümrüt; Çiftçi, Ergin; Bayhan, Gülsüm İclal; Gayretli Aydın, Zeynep Gökçe; Öcal Demir, Sevliya; Kılıç, Ömer; Hacımustafaoğlu, Mustafa; Şener Okur, Dicle; Şen, Semra; Yahşi, Aysun; Çetin, Benhur; Sütçü, Murat; Kara, Manolya; Uygun, Hatice; Tural Kara, Tuğçe; Korukluoğlu, Gülay; Akgün, Özlem; Üstündağ, Gülnihan; Demir Mis, Mevsim; Salı, Enes; Kaba, Özge; Yakut, Nurhayat; Kılıç, Orhan; Kanık, M. Kemal; Çetin, Ceren; Dursun, Adem; Çiçek, Muharrem; Koçkuzu, Esra; Şevketoğlu, Esra; Alkan, Gülsüm; Güner Özenen, Gizem; İnce, Erdal; Baydar, Zekiye; Özkaya, Ahmet Kağan; Ovalı, Hüsnü Fahri; Tekeli, Seher; Çelebi, Solmaz; Çubukçu, Birgül; Bal, Alkan; Köse, Mehmet; Hatipoğlu, Halil Uğur; Dalkıran, Tahir; Turgut, Mehmet; Başak Altaş, Ayşe; Selçuk Duru, Hatice Nilgün; Aksay, Ahu; Sağlam, Sevcan; Sarı Yanartaş, Mehpare; Ergenç, Zeynep; Akın, Yasemin; Düzenli Kar, Yeter; Şahin, Sabit; Tüter Öz, Şadiye Kübra; Bilen, Nimet Melis; Özdemir, Halil; Şenoglu, Mine Çiğdem; Parıltan Küçükalioğlu, Burcu; Besli, Gülser Esen; Kara, Yalçın; Turan, Cansu; Selbest Demirtaş, Burcu; Coşgun, Yasemin; Elevli, Murat; Şahin, Aslıhan; Bahtiyar Oğuz, Şerife; Somer, Ayper; Karadağ, Bülent; Demirhan, Recep; Türk Dağı, Hatice; Kurugöl, Zafer; Taşkın, Esra Çakmak; Şahiner, Ayşegül; Yeşil, Edanur; Ekemen Keleş, Yıldız; Sarıkaya, Remzi; Erdem Eralp, Ela; Özkınay, Ferda; Konca, Hatice Kübra; Yılmaz, Songül; Gökdemir, Yasemin; Arga, Gül; Özen, Seval; Çoksüer, Fevziye; Vatansever, Göksel; Tezer, Hasan; Kara, Ateş

Abstract

Objectives: the aim of this study is to identify the epidemiological, clinical, and laboratory features of coronavirus disease 2019 (COVID-19) in children.Methods: a retrospective study was conducted by pediatric infectious disease specialists from 32 different hospitals from all over Turkey by case record forms. Pediatric cases who were diagnosed as COVID-19 between March 16, 2020, and June 15, 2020 were included. Case characteristics including age, sex, dates of disease onset and diagnosis, family, and contact information were recorded. Clinical data, including the duration and severity of symptoms, were also collected. Laboratory parameters like biochemical tests and complete blood count, chest X-ray, and chest computed tomography (CT) were determined. Results: there were 1,156 confirmed pediatric COVID-19 cases. In total, male cases constituted 50.3% (n = 582) and females constituted 49.7% (n = 574). The median age of the confirmed cases was 10.75 years (4.5-14.6). Of the total cases, 90 were younger than 1 year of age (7.8%), 108 were 1-3 years of age (9.3%), 148 were 3-6 years of age (12.8%), 298 were 6-12 years of age (25.8%), 233 were 12-15 years of age (20.2%), and 268 cases were older than 15 years of age (23.2%). The most common symptom of the patients at the first visit was fever (50.4%) (n = 583) for a median of 2 days (IQR: 1-3 days). Fever was median at 38.4 degrees C (38.0-38.7 degrees C). The second most common symptom was cough (n = 543, 46.9%). The other common symptoms were sore throat (n = 143, 12.4%), myalgia (n = 141, 12.2%), dyspnea (n = 118, 10.2%), diarrhea (n = 112, 9.7%), stomachache (n = 71, 6.1%), and nasal discharge (n = 63, 5.4%). When patients were classified according to disease severity, 263 (22.7%) patients were asymptomatic, 668 (57.7%) patients had mild disease, 209 (18.1%) had moderate disease, and 16 (1.5%) cases had severe disease. One hundred and forty-nine (12.9%) cases had underlying diseases among the total cases; 56% of

Published
2021

42. The epidemiology and economic impact of varicella-related hospitalizations in Turkey from 2008 to 2010: a nationwide survey during the pre-vaccine era (VARICOMP study)

Author

Dinleyici, Ener Cagri, Kurugol, Zafer, Turel, Ozden, Hatipoglu, Nevin, Devrim, Ilker, Agin, Hasan, Gunay, Ilker, Yasa, Olcay, Erguven, Muferet, Bayram, Nuri, Kizildemir, Ali, Alhan, Emre, Kocabas, Emine, Tezer, Hasan, Aykan, H. Hakan, Dalgic, Nazan, Kilic, Betul, Sensoy, Gulnar, Belet, Nursen, Kulcu, Nihan Uygur, Say, Aysu, Tas, Mehmet Ali, Ciftci, Ergin, Ince, Erdal, Ozdemir, Halil, Emiroglu, Melike, Odabas, Dursun, Yargic, Zeynel Abidin, Nuhoglu, Cagatay, Carman, Kursat Bora, Celebi, Solmaz, Hacimustafaoglu, Mustafa, Elevli, Murat, Ekici, Zahide, Celik, Umit, Kondolot, Meda, Ozturk, Mustafa, Tapisiz, Anil, Ozen, Metehan, Tepeli, Harun, Parlakay, Aslinur, Kara, Ates, Somer, Ayper, Caliskan, Bahar, Velipasalioglu, Sevtap, Oncel, Selim, Arisoy, Emin Sami, Guler, Ekrem, Dalkiran, Tahir, Aygun, Denizmen, Akarsu, Saadet, and VARICOMP Study Group

Published
2012
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45. Epidemiological, Clinical, and Laboratory Features of Children With COVID-19 in Turkey

Author

Karbuz, Adem, primary, Akkoc, Gulsen, additional, Bedir Demirdag, Tugba, additional, Yilmaz Ciftdogan, Dilek, additional, Ozer, Arife, additional, Cakir, Deniz, additional, Hancerli Torun, Selda, additional, Kepenekli, Eda, additional, Erat, Tugba, additional, Dalgic, Nazan, additional, Ilbay, Sare, additional, Karaaslan, Ayse, additional, Erdeniz, Emine H., additional, Aygun, F. Deniz, additional, Bozdemir, S. Elmas, additional, Hatipoglu, Nevin, additional, Emiroglu, Melike, additional, Sahbudak Bal, Zumrut, additional, Ciftci, Ergin, additional, Bayhan, Gulsum Iclal, additional, Gayretli Aydin, Zeynep Gokce, additional, Ocal Demir, Sevliya, additional, Kilic, Omer, additional, Hacimustafaoglu, Mustafa, additional, Sener Okur, Dicle, additional, Sen, Semra, additional, Yahsi, Aysun, additional, Akturk, Hacer, additional, Cetin, Benhur, additional, Sutcu, Murat, additional, Kara, Manolya, additional, Uygun, Hatice, additional, Tural Kara, Tugce, additional, Korukluoglu, Gulay, additional, Akgun, Ozlem, additional, Üstündağ, Gülnihan, additional, Demir Mis, Mevsim, additional, Sali, Enes, additional, Kaba, Ozge, additional, Yakut, Nurhayat, additional, Kılıc, Orhan, additional, Kanik, M. Kemal, additional, Cetin, Ceren, additional, Dursun, Adem, additional, Cicek, Muharrem, additional, Kockuzu, Esra, additional, Sevketoglu, Esra, additional, Alkan, Gulsum, additional, Guner Ozenen, Gizem, additional, İnce, Erdal, additional, Baydar, Zekiye, additional, Ozkaya, Ahmet Kagan, additional, Ovali, Husnu Fahri, additional, Tekeli, Seher, additional, Celebi, Solmaz, additional, Cubukcu, Birgul, additional, Bal, Alkan, additional, Khalilova, Fidan, additional, Kose, Mehmet, additional, Hatipoglu, Halil Ugur, additional, Dalkiran, Tahir, additional, Turgut, Mehmet, additional, Basak Altas, Ayse, additional, Selcuk Duru, Hatice Nilgün, additional, Aksay, Ahu, additional, Saglam, Sevcan, additional, Sari Yanartas, Mehpare, additional, Ergenc, Zeynep, additional, Akin, Yasemin, additional, Duzenli Kar, Yeter, additional, Sahin, Sabit, additional, Tuteroz, Sadiye Kubra, additional, Bilen, Nimet Melis, additional, Ozdemir, Halil, additional, Senoglu, Mine Cidem, additional, Pariltan Kucukalioglu, Burcu, additional, Besli, Gulser Esen, additional, Kara, Yalcin, additional, Turan, Cansu, additional, Selbest Demirtas, Burcu, additional, Celikyurt, Aydın, additional, Cosgun, Yasemin, additional, Elevli, Murat, additional, Sahin, Aslihan, additional, Bahtiyar Oguz, Serife, additional, Somer, Ayper, additional, Karadag, Bulent, additional, Demirhan, Recep, additional, Turk Dagi, Hatice, additional, Kurugol, Zafer, additional, Taskin, Esra Cakmak, additional, Sahiner, Aysegul, additional, Yesil, Edanur, additional, Ekemen Keles, Yildiz, additional, Sarikaya, Remzi, additional, Erdem Eralp, Ela, additional, Ozkinay, Ferda, additional, Konca, Hatice Kubra, additional, Yilmaz, Songul, additional, Gokdemir, Yasemin, additional, Arga, Gul, additional, Ozen, Seval, additional, Coksuer, Fevziye, additional, Vatansever, Goksel, additional, Tezer, Hasan, additional, and Kara, Ates, additional

Published
2021
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46. Nörojenik Mesaneli Çocuklarda Serum Çinko Düzeyinin Değerlendirilmesi.

Author

Baş, Ahmet İbrahim, Aksu, Bağdagül, Ağbaş, Ayşe, Baş, Cansu, and Elevli, Murat

Subjects
NEUROGENIC bladder, MINERAL supplements, MINERAL deficiency, ALKALINE phosphatase, PEDIATRIC nephrology
Abstract

Copyright of Journal of the Child / Çocuk Dergisi is the property of Journal of Child and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2022
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48. The frequency of and factors affecting functional gastrointestinal disorders in infants that presented to tertiary care hospitals

Author

Beser, Omer Faruk, primary, Cullu Cokugras, Fugen, additional, Dogan, Guzide, additional, Akgun, Ozlem, additional, Elevli, Murat, additional, Yilmazbas, Pinar, additional, Ocal, Meric, additional, Bayrak, Nevzat Aykut, additional, Sezer Yamanel, Rabia Gonul, additional, Bozaykut, Abdulkadir, additional, Celtik, Coşkun, additional, Polat, Esra, additional, Gerenli, Nelgin, additional, Bozlak, Serdar, additional, Ayyildiz Civan, Hasret, additional, Ozkul Saglam, Neslihan, additional, Hatipoglu, Sadik Sami, additional, Özgürhan, Gamze, additional, Sunnetci Silistre, Eda, additional, Solmaz, Burcu, additional, Kutluk, Gunsel, additional, Genc, Hamide Sevinc, additional, Onal, Hasan, additional, Usta, Ayse Merve, additional, Urganci, Nafiye, additional, Sahin, Ayse, additional, Cam, Sebahat, additional, Yildirim, Sema, additional, Yildirim, Asilay, additional, and Vandenplas, Yvan, additional

Published
2021
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50. Yüksek Karaciğer Fonksiyon Testleri ile Dilate Kardiyomiyopati İlişkisi

Author

Bay, Eda Dilara, Yolcu, Canan, DOĞAN, GÜZİDE, SELÇUK DURU, HATİCE NİLGÜN, ELEVLİ, MURAT, and DOĞAN, GÜZİDE

Subjects
Bay E. D. , Yolcu C., DOĞAN G., SELÇUK DURU H. N. , ELEVLİ M., -Yüksek Karaciğer Fonksiyon Testleri ile Dilate Kardiyomiyopati İlişkisi-, 8. Çocuk Dostaları Kongresi, Türkiye, 12 - 14 Mart 2020
Published
2020

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