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Francis Elliott's papers consist of letters (1866-1871) to his family discussing his experiences in Virginia City and Beartown, Montana Territory, where he was a miner, farmer, and freighter. Also included are three letters (1880-1881) to Elliott's brother, George, from Joseph Skettington concerning Elliott's death, burial, and estate., This collection consists of ten letters (1866-1871) from Frank Elliott in Montana to his family in Illinois. The letters describe the beauty of Montana, the physical hardships of the bitter winters, a planned civilian campaign against the Indians, and economic difficulties. The last letter in 1871 expresses considerable disillusionment with Montana. There are also three letters (1880-1881) to Elliott's brother from Joseph Skeffington of Bear Town, telling of Elliott's death in 1875. (Small Collection 660)

Background: Changing etiologic patterns and the growing problem of antimicrobial resistance, particularly an increase in macrolide-resistant pneumococcal bacteremia, are causing physicians to adopt new approaches to the treatment of community-acquired pneumonia (CAP). Objective: The relative efficacy and tolerability of levofloxacin monotherapy and azithromycin and ceftriaxone combination therapy were assessed in hospitalized adults with moderate to severe CAP. Methods: This Phase IV, multicenter, open-label, randomized trial compared 2 treatment regimens: (1) levofloxacin 500 mg PO or IV q24h, and (2) azithromycin 500 mg IV q24h for ≥2 days plus ceftriaxone 1 g IV q24h for 2 days, followed by an optional transition to azithromycin 500 mg PO q24h at the investigator's discretion. The total duration of therapy was to be a minimum of 10 days in both treatment groups. Ceftriaxone was included in the initial azithromycin regimen to ensure coverage against pneumococcal bacteremia. Results: Of 236 patients in the intent-to-treat population, completion or withdrawal information was available for 110 patients in the levofloxacin group and 114 in the azithromycin group. Baseline demographic and disease characteristics were comparable between groups. At the end of treatment, the clinical success rate (cured + improved) in clinically evaluable patients was 94.1% in the levofloxacin group and 92.3% in the azithromycin group. The respective post-therapy microbiologic eradication rates were 89.5% and 92.3%. Levofloxacin was as well tolerated as azithromycin, with an incidence of drug-related adverse events (AEs) for all body systems of 5.3% and 9.3%, respectively. One patient receiving levofloxacin had a serious drug-related AE, compared with 7 patients receiving azithromycin. Conclusions: In this study in hospitalized patients with moderate to severe CAP, levofloxacin monotherapy was at least as effective as a combination regimen of azithromycin and ceftriaxone in providing coverage against the current causative pathogens in CAP. In addition, levofloxacin was as well tolerated as the combination of azithromycin and ceftriaxone.

Western cultural approaches to teaching science have excluded Indigenous knowledges and culturally favored many non-Aboriginal science students. By asking the question “What connections exist between Western science and Indigenous knowledge?” elements of epistemological (how do we determine what is real?) and ontological (what is real?) connections can emerge for science educators. Western science as it is presented in Alberta classrooms is characterized as teaching scientism by the degree to which it excludes the presentation of other ways of knowing. The objectivity of Western science is questioned here, and aspects of Indigenous knowledge are suggested that coincide with and can support science teaching. The concept of indeterminacy and flux as suggested by Bohm (1980), Little Bear (2004), and Peat (2002) form a nexus where Western scientific epistemologies and ontologisms are congruent with Indigenous knowledge. Metaphoric meaning is suggested as one useful area of congruence for science education praxis., Alberta Journal of Educational Research, Vol. 55 No. 3 (2009): Fall (Theme Issue)

Winston-Salem is a proud city with a rich heritage. Throughout its history, it has continually overcome the challenges of modernization with forward-looking strategies based in entrepreneurship and economic diversification, which continue to facilitate the city’s growth today.