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2. Stillbirths: recall to action in high-income countries

Author

Flenady, Vicki, Frøen, J Frederik, Kinney, Mary V, de Bernis, Luc, Lawn, Joy E, Blencowe, Hannah, Heazell, Alexander, Leisher, Susannah Hopkins, Ruidiaz, Jessica, Carvalho, Andre, Dahlstrom, Jane, East, Christine, Fox, Jane P, Gibbons, Kristen, Ibiebele, Ibinabo, Kildea, Sue, Gardener, Glenn, Lourie, Rohan, Wilson, Patricia, Gordon, Adrienne, Jennings, Belinda, Kent, Alison, McDonald, Susan, Merchant, Kelly, Oats, Jeremy, Walker, Susan P, Raven, Leanne, Schirmann, Anne, de Montigny, Francine, Guyon, Grace, Blondel, Beatrice, de Wall, Sabine, Bonham, Sheelagh, Corcoran, Paul, Cregan, Mairie, Meany, Sarah, Murphy, Margaret, Fukui, Stephanie, Gordijn, Sanne, Korteweg, Fleurisca, Cronin, Robin, Mason, Vicki, Culling, Vicki, Usynina, Anna, Pettersson, Karin, Rådestad, Ingela, van Gogh, Susanne, Bichara, Bia, Bradley, Stephanie, Ellis, Alison, Downe, Soo, Draper, Elizabeth, Manktelow, Brad, Scott, Janet, Smith, Lucy, Stones, William, Lavender, Tina, Duke, Wes, Fretts, Ruth C, Gold, Katherine J, McClure, Elizabeth, Reddy, Uma, Wojcieszek, Aleena M, Middleton, Philippa, Ellwood, David, Erwich, Jan Jaap, Coory, Michael, Khong, T Yee, Silver, Robert M, Smith, Gordon C S, Boyle, Frances M, Gross, Mechthild M, Horey, Dell, Farrales, Lynn, Bloomfield, Frank, McCowan, Lesley, Brown, Stephanie J, Joseph, K S, Zeitlin, Jennifer, Reinebrant, Hanna E, Cacciatore, Joanne, Ravaldi, Claudia, Vannacci, Alfredo, Cassidy, Jillian, Cassidy, Paul, Farquhar, Cindy, Wallace, Euan, Siassakos, Dimitrios, Heazell, Alexander E P, Storey, Claire, Sadler, Lynn, Petersen, Scott, and Goldenberg, Robert L

Published
2016
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6. Contributors

Author

Abecassis, Isaac Josh, Abeysekera, Jayani, Adelson, P. David, Agbeko, Rachel S., Agus, Michael S.D., Ahmed, Mubbasheer, Akhondi-Asl, Alireza, Albert, Ben D., Alcamo, Alicia, Alder, Matthew N., Alibrahim, Omar, Allareddy, Veerajalandhar, Almodovar, Melvin C., Aminoff, Alexandra, Amlie-Lefond, Catherine, Aneja, Rajesh, Apple, Abigail, Argent, Andrew C., Arvedson, Joan C., Aspesberro, François, Atlas, Nir, Baatz, John E., Baden, Harris P., Bakar, Adnan M., Banker, Katherine, Barker, Piers C.A., Bass, Lee M., Basu, Rajit K., Bayir, Hülya, Becker, Lance B., Bell, Jamie L., Bell, Michael J., Bembea, Melania M., Bender, M.A., Benscoter, Alexis L., Benton, Wade W., Berg, Robert A., Berkman, Emily, Berkowitz, Carol, Biagas, Katherine V., Bishop, Naomi B., Blatt, Julie, Bodilly, Lauren, Bonow, Robert H., Bragg, E. Alexis, Brandom, Barbara W., Brilli, Richard J., Brogan, Thomas V., Bronicki, Ronald A., Browd, Samuel R., Bunchman, Timothy E., Burns, Jeffrey P., Butler, David F., Caglar, Derya, Camitta, Michael W., Campbell, M. Jay, Campbell, Sally, Capek, Karel D., Carboni, Michael P., Carcillo, Joseph A., Cassara, Antonio, Censoplano, Nina, Chadwick, Victoria, Chamberlain, Reid C., Chan, Anny, Charpie, John R., Cheifetz, Ira M., Chiwane, Saurabh, Chun, Robert H., Clark, Jeff, Clark, Jonna D., Clark, Robert S.B., Clawson, April, Clayton, Jason A., Conlon, Thomas, Conrad, Carol, Conway, Edward E., Jr, Coopersmith, Craig M., Corey, Seth J., Dahmer, Mary K., Dalton, Heidi J., Damania, Rahul C., Damian, Mihaela A., Dartois, Lauren, Davis, Peter J., Dervan, Leslie A., Deutschman, Clifford S., Dezfulian, Cameron, Dick, André A.S., Diekema, Douglas S., Dingeldein, Michael, Doctor, Allan, Downes, John J., Duncan, Christine, Edwards, Christopher M., Edwards, Lauren R., Egbuta, Chinyere, Eigen, Howard, Elfassy, Hannah Laure, Ellis, Alison M., Evans, Idris V.R., Farris, Reid W.D., Fineman, Jeffrey R., Fink, Ericka L., Fish, Frank A., Fitzgerald, Tamara N., Fleming, Gregory A., Flores, Saul, Flynn, Joseph T., Forbes, Michael L., Forbess, Joseph M., Franzon, Deborah E., Frazier, W. Joshua, Fuhrman, Bradley P., Ginther, Richard M., Jr, Glaser, Nicole, Graciano, Ana Lia, Gray, Megan M., Greathouse, Kristin C., Greenwald, Bruce M., Grinsell, Matthew M., Grunwell, Jocelyn R., Gunnarsson, Björn, Guzman, Marla, Hahn, Timothy, Hall, Mark W., Harding, Cary O., Hartman, Mary E., Hartmann, Silvia M., Havlin, Kevin M., Hayward, Kristen, Healey, Patrick J., Heard, Christopher M.B., Heneghan, Julia A., Herndon, David N., Hernan, Lynn J., Hill, Kevin D., Hoffman, Julien I., Holinski, Paula, Hong, Sue J., Horslen, Simon, Hoskote, Aparna, Hotz, Justin C., Ibsen, Laura Marie, Ijsselstijn, Hanneke, Jackson, Travis C., Jamal, Shelina M., Joshi, Prashant, Joyce, Emily L., Kallay, Tom, Kamat, Pradip P., Kane, Jason M., Kannankeril, Prince J., Karam, Oliver, Kenningham, Katherine L., Khalatbari, Hedieh, Khemani, Robinder G., Killien, Elizabeth Y., Kim, Yun, Kingsley, Jenny, Kirk, Christa Jefferis, Kirmani, Sonya, Kleinpell, Ruth, Kochanek, Patrick M., Kocis, Keith C., Kocoshis, Samuel A., Koves, Ildiko H., Kudchadkar, Sapna R., Kulik, Thomas J., Lacroix, Jacques, Lebet, Ruth, Lee, Amy, Lenker, Hallie, Levin, Daniel L., Levy, Emily R., Lewis-Newby, Mithya, Lin, John C., Maddux, Aline, Malone, Matthew P., Manole, Mioara, Marsh, Anne, Martin, Richard J., Mathur, Mudit, McArthur, Jennifer, McCusker, Christine, McDonald, Ruth A., Mehta, Nilesh M., Melvin, Ann J., Menon, Shina, Monagle, Paul, Morgan, Ryan W., Morgenstern, Peter F., Morowitz, Michael J., Morrison, Wynne, Munshi, Raj, Muszynski, Jennifer A., Nadkarni, Vinay M., Naiditch, Jessica A., Nakagawa, Thomas A., Nguyen, Vu, Nickless, Jenna R., Nishisaki, Akira, Norwood, Victoria F., Notterman, Daniel A., Oishi, Peter, Ojemann, Jeffrey, Olson, Michelle L., O’Neal, Jessie, Orloff, Kirsten, Otteson, Todd, Ouellette, Yves, Parakininkas, Daiva, Parker, Robert I., Peeler, Katherine Ratzen, Perez, Francisco A., Perry, Melvin G., Jr, Peters, Mark J., Pfeiffer, Brent J., Phelan, Rachel, Philip, Joseph, Pinto, Neethi, Pollack, Murray M., Preston, Thomas J., Prodhan, Parthak, Quang, Lawrence, Quasney, Michael W., Raffay, Thomas M., Rajapreyar, Prakadeshwari, Rakes, Lauren, Ramos-Jimenez, Rafael G., Ray, Samiran, Reed, Christopher R., Reese, James J., Jr, Rehder, Kyle J., Remy, Kenneth E., Reyes, Jorge D., Rhee, Eileen, Richardson, Clare, Roberts, Joan S., Guerineau, Luciana Rodriguez, Rogers, Stephen, Rotta, Alexandre T., Rowin, Mark E., Ruppel, Randall, Ryan, Rita M., Said, Ahmed, Sallee, Colin J., Sandler, Britt Julia, Sankar, Jhuma, Sarnaik, Ajit A., Sarnaik, Ashok P., Sawin, Robert, Schenkman, Kenneth A., Schexnayder, Stephen M., Schleien, Charles L., Schwartz, Stephanie P., Schwartz, Steven M., Shah, Jay, Shah, Sareen, Shaw, Dennis W.W., Shein, Steven L., Shoykhet, Michael, Simon, Dennis W., Sivarajan, V. Ben, Slain, Katherine N., Smith, Jodi M., Smith, Lincoln S., Sochet, Anthony A., Sorce, Lauren R., Sousse, Linda E., Spaeder, Michael C., Speicher, Richard H., Spinella, Philip C., Stalets, Erika L., Standage, Stephen Wade, Stark, Rebecca, Starr, Michelle C., Steinhorn, David M., Stenmark, Kurt R., Stewart, Claire A., Stollings, Lindsay M., Stulce, Casey, Su, Erik, Summers, Corinne, Sutton, Robert M., Symons, Jordan M., Sznycer-Taub, Nathaniel R., Tamburro, Robert T., Jr, Tapking, Christian, Tasker, Robert C., Tatum, Gregory H., Tilton, Ann H., Timlin, Matthew R., Tissieres, Pierre, Tobias, Joseph D., Toltzis, Philip, Topjian, Alexis A., Torgerson, Troy, Traube, Chani, Tucci, Marisa, Tuggle, David, Turi, Jennifer L., Turner, David A., Cleave, Alisa Van, van der Velden, Meredith G., Vogel, Adam M., Vohwinkel, Christine, Andre-von Arnim, Amelie von Saint, Vora, Surabhi B., Waghmare, Alpana, Wainwright, Mark S., Wallisch, Jessica S., Watson, R. Scott, Watt, Kevin, Weimer, Maria, Weiss, Scott L., Wenger, Jesse, Wheeler, Derek S., Wieczorek, Beth, Wilhelm, Michael, Wong, Hector R., Woods, Charles R., Jr, Woodward, George A. (Tony), Yang, Amy C., Yu, Heidi, Zane, Nicole R., Zerr, Danielle M., Zhang, Hui, Zheng, Hengqi (Betty), Zimmerman, Jerry J., Zimmerman, Kanecia, Zinter, Matt S., and Zuppa, Athena F.

Published
2022
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10. Bosutinib (BOS) vs Imatinib (IM) for Newly Diagnosed Chronic Myeloid Leukemia (CML): Initial Results from the BFORE Trial

Author

Cortes, Jorge, primary, Gambacorti-Passerini, Carlo, additional, Deininger, Michael, additional, Mauro, Michael, additional, Chuah, Charles, additional, Kim, Dong Wook, additional, Reilly, Laurence, additional, Jeynes-Ellis, Alison, additional, Leip, Eric, additional, Bardy-Bouxin, Nathalie, additional, Hochhaus, Andreas, additional, and Brümmendorf, Tim, additional

Published
2017
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11. From grief, guilt pain and stigma to hope and pride – a systematic review and meta-analysis of mixed-method research of the psychosocial impact of stillbirth

Author

Burden, Christy, Bradley, Stephanie, Storey, Claire, Ellis, Alison, Heazell, Alexander E. P., Downe, Soo, Cacciatore, Joanne, Siassakos, Dimitrios, Burden, Christy, Bradley, Stephanie, Storey, Claire, Ellis, Alison, Heazell, Alexander E. P., Downe, Soo, Cacciatore, Joanne, and Siassakos, Dimitrios

Abstract

Background Despite improvements in maternity healthcare services over the last few decades, more than 2.7 million babies worldwide are stillborn each year. The global health agenda is silent about stillbirth, perhaps, in part, because its wider impact has not been systematically analysed or understood before now across the world. Our study aimed to systematically review, evaluate and summarise the current evidence regarding the psychosocial impact of stillbirth to parents and their families, with the aim of improving guidance in bereavement care worldwide. Methods Systematic review and meta-summary (quantitative aggregation of qualitative findings) of quantitative, qualitative, and mixed-methods studies. All languages and countries were included. Results Two thousand, six hundred and nineteen abstracts were identified; 144 studies were included. Frequency effect sizes (FES %) were calculated for each theme, as a measure of their prevalence in the literature. Themes ranged from negative psychological symptoms post bereavement (77 · 1) and in subsequent pregnancies (27 · 1), to disenfranchised grief (31 · 2), and incongruent grief (28 · 5), There was also impact on siblings (23 · 6) and on the wider family (2 · 8). They included mixed-feelings about decisions made when the baby died (12 · 5), avoidance of memories (13 · 2), anxiety over other children (7 · 6), chronic pain and fatigue (6 · 9), and a different approach to the use of healthcare services (6 · 9). Some themes were particularly prominent in studies of fathers; grief suppression (avoidance)(18 · 1), employment difficulties, financial debt (5 · 6), and increased substance use (4 · 2). Others found in studies specific to mothers included altered body image (3 · 5) and impact on quality of life (2 · 1). Counter-intuitively, Some themes had mixed connotations. These included parental pride in the baby (5 · 6), motivation for engagement in healthcare improvement (4 · 2) and changed approaches to life and death

Published
2016

14. Amatuximab, a chimeric monoclonal antibody to mesothelin, in combination with pemetrexed and cisplatin in patients with unresectable pleural mesothelioma: Results of a multicenter phase II clinical trial.

Author

Hassan, Raffit, primary, Jahan, Thierry Marie, additional, Kindler, Hedy Lee, additional, Bazhenova, Lyudmila, additional, Reck, Martin, additional, Pastan, Ira, additional, Ellis, Alison, additional, Fatato, Penny Marie, additional, Heyburn, John, additional, Schweizer, Charles, additional, Parno, Jeff, additional, and Wallin, Bruce, additional

Published
2012
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18. Your countryside.

Author

Stevenson, Roger, Nott, Paul, Collins, Fergus, Ellis, Alison, Bloomfield, Hazel, Hudson, Mary, and Pinfold, Lydia

Published
2021

19. The differential effects of stanozolol on human skin and synovial fibroblasts in vitro: DNA synthesis and receptor binding.

Author

Ellis, Alison, Cawston, Tim, and Mackie, Eleanor

Abstract

The anabolic steroid stanozolol stimulates the production of prostaglandin E (PGE) and the matrix metalloproteinases collagenase and stromelysin in human skin fibroblasts but not in rheumatoid synovial fibroblasts. The basis for these differential responses was investigated at the levels of DNA synthesis and steroid receptor binding. Stanozolol inhibited fibroblast growth factor (FGF)-stimulated DNA synthesis in both the skin and synovial fibroblasts, showing that both cell types were capable of responding to the compound. Competitive binding assays indicated that stanozolol bound specifically to both the skin and synovial fibroblasts. Binding of stanozolol to both cell types could be partially displaced by progesterone, indicating that stanozolol binds to the progesterone receptor. Immunocytochemical studies confirmed the presence of progesterone receptors on skin and synovial fibroblasts. However, progesterone failed to elicit any response with respect to collagenase production in either cell type. Nortestosterone, dexamethasone and 17β-oestradiol had no effect on binding of stanozolol to either cell type. These results indicate that the inhibition of DNA synthesis by stanozolol is elicited through the progesterone receptor. The effects of stanozolol on collagenase and PGE production are mediated by a different receptor, present on skin but not synovial fibroblasts, and as yet unidentified. [ABSTRACT FROM AUTHOR]

Published
1994
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45. Book Reviews.

Author

Golightley, Malcolm, Ellis, Alison, Nash, Sue, Tyler, Gina Marie, Hardy, Kev, and Matthews, Carolyn

Subjects
*NONFICTION
Abstract

The article reviews several books including "By Their Own Hand: Deliberate Self-Harm and Suicidal Ideas in Adolescents," by K. Hawton, K. Rodham and E. Evans, "Youth Offending in Transition: The Search for Social Recognition," by M. Barry and "Social Work with People with Learning Difficulties," by P. Williams.

Published
2007
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46. Racial and Ethnic Disparities in Cancer Survival: The Contribution of Tumor, Sociodemographic, Institutional, and Neighborhood Characteristics.

Author

Ellis L, Canchola AJ, Spiegel D, Ladabaum U, Haile R, and Gomez SL

Subjects
Aged, Breast Neoplasms diagnosis, Breast Neoplasms ethnology, California, Colorectal Neoplasms diagnosis, Colorectal Neoplasms ethnology, Educational Status, Female, Health Status Disparities, Humans, Lung Neoplasms diagnosis, Lung Neoplasms ethnology, Male, Middle Aged, Neoplasms diagnosis, Prostatic Neoplasms diagnosis, Prostatic Neoplasms ethnology, Residence Characteristics, Risk Factors, Social Class, Survival Analysis, United States, Black or African American statistics & numerical data, Asian statistics & numerical data, Hispanic or Latino statistics & numerical data, Neoplasms ethnology, Registries statistics & numerical data, White People statistics & numerical data
Abstract

Purpose Racial/ethnic disparities in cancer survival in the United States are well documented, but the underlying causes are not well understood. We quantified the contribution of tumor, treatment, hospital, sociodemographic, and neighborhood factors to racial/ethnic survival disparities in California. Materials and Methods California Cancer Registry data were used to estimate population-based cancer-specific survival for patients diagnosed with breast, prostate, colorectal, or lung cancer between 2000 and 2013 for each racial/ethnic group (non-Hispanic black, Hispanic, Asian American and Pacific Islander, and separately each for Chinese, Japanese, and Filipino) compared with non-Hispanic whites. The percentage contribution of factors to overall racial/ethnic survival disparities was estimated from a sequence of multivariable Cox proportional hazards models. Results In baseline models, black patients had the lowest survival for all cancer sites, and Asian American and Pacific Islander patients had the highest, compared with whites. Mediation analyses suggested that stage at diagnosis had the greatest influence on overall racial/ethnic survival disparities accounting for 24% of disparities in breast cancer, 24% in prostate cancer, and 16% to 30% in colorectal cancer. Neighborhood socioeconomic status was an important factor in all cancers, but only for black and Hispanic patients. The influence of marital status on racial/ethnic disparities was stronger in men than in women. Adjustment for all covariables explained approximately half of the overall survival disparities in breast, prostate, and colorectal cancer, but it explained only 15% to 40% of disparities in lung cancer. Conclusion Overall reductions in racial/ethnic survival disparities were driven largely by reductions for black compared with white patients. Stage at diagnosis had the largest effect on racial/ethnic survival disparities, but earlier detection would not entirely eliminate them. The influences of neighborhood socioeconomic status and marital status suggest that social determinants, support mechanisms, and access to health care are important contributing factors.

Published
2018
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