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Barley is an important food crop particularly for animal feeding and human food over the word, which infested by Rhyzopertha dominica (F.) insects at stored grain stage. Using modern methods of protection of stored grains from insect pests within integrated management (IPM) programs is an important approach. Ten hulled Egyptian barley cultivars were grown at Sakha Agricultural research station farm during two growing seasons 2020/ 2021 and 2021/ 2022 to evaluated their susceptible to R. dominica after 180 days from seeds storage. The influence of using phenol application on R. dominica and chemical properties of the barley grain were evaluated. The results showed that the barley cultivars (Giza123, Giza 2000, Giza137 and Giza138) were the lowest cultivars infested by R. dominica, which showed least reduction of weight loss and least percentage of grain infestation. Positive significant correlation was found among all insect infestation traits with protein content and total carbohydrates content. The loadings of principal component analysis PCA described about 96.4 % of the total variability of all studied traits. The heatmap cluster analysis, clustered all the ten hulled barley into two major clusters based on their productivity, grain quality and R. dominica infestation characters. Using phenol concentration of (0.4 g ai / kg) exhibited high toxic for R. dominica insect, showed lower LC50 values for Giza 132, Giza2000, Giza137 and Giza138 by (1.80, 2.08, 2.60, and 2.60 g ai / kg grains), high response index percentage (100.00, 85.50, 69.23 and 69.23%) with complete reduction of adult progeny of R. dominica after 120 hrs. of exposure. The technological quality of barley cultivars grains haven’t showing any significant change after treated with different phenol treatments.

The present experiment was conducted to determine the effect chemical fertilization rates and foliar application of plant growth regulators PGRs (Kinetin or Napthaleneacetic Acid (NAA) and their interactions on growth, flowering, chemical composition of Ervatamia coronaria plants. The plants were fertilized monthly with NPK at the rate of 2, 4 and 6 g pot-1, in addition to the control plants. Plants received the fertilization treatments were sprayed monthly with either Kinetin or NAA at 50, 100 ppm for each one, while the control plants sprayed with tap water. As general, the results indicated that within each level of fertilizer treatments, treating plants with different concentrations of PGRs (Kinetin or NAA) resulted in significant increase in tested vegetative growth (in terms of plant height, number of branches plant-1, leaf area, number of leaves plant-1, stem diameter, root length, fresh and dry weights of leaves, stems and roots), flowering parameters (Viz number of flowers/ plant, fresh and dry weights of flowers), chlorophylls content, total carbohydrates, N, P , K%, total indoles and total phenols, gibberellins, auxins and cytokinins compared to control, with superiority of NAA particularly the highest concentrations (100 ppm) . Under the same level of PGRs raising the fertilization rate caused a gradual and significant increase in all tested parameters compared to control. Based on the results, it can be recommended that for the highest quality growth and flowering parameters of Ervatamia coronaria, the plants could be sprayed with NAA at 100 ppm combined with 6 g pot-1 NPK. Resumo O presente experimento foi conduzido para determinar o efeito das taxas de fertilização química e aplicação foliar de reguladores de crescimento de plantas PGRs (Cinetina ou Ácido Naftalenoacético (ANA) e suas interações no crescimento, floração, composição química de plantas de Ervatamia coronaria. as plantas foram fertilizadas mensalmente com NPK na dose de 2, 4 e 6 g/vaso, além das plantas controle. As plantas que receberam os tratamentos de fertilização foram pulverizadas mensalmente com cinetina ou ANA a 50, 100 ppm para cada uma, enquanto as plantas controle foram pulverizadas com água da torneira . Em geral, os resultados indicaram que, dentro de cada nível de tratamentos de fertilizantes, o tratamento de plantas com diferentes concentrações de PGRs (cinetina ou ANA) resultou em aumento significativo no crescimento vegetativo testado (em termos de altura da planta, número de ramos planta-1, área foliar , número de folhas planta-1, diâmetro do caule, comprimento da raiz, pesos frescos e secos de folhas, caules e raízes), parâmetros de floração (Viz número de flores planta-1, massa fresca e seca de flores), teor de clorofilas, carboidratos totais, N, P, K%, indóis totais e fenóis totais, giberelinas, auxinas e citocininas em relação ao controle, com superioridade de ANA principalmente nas concentrações mais altas (100 ppm). Sob o mesmo nível de PGRs o aumento da taxa de adubação causou um aumento gradual e significativo em todos os parâmetros testados em relação ao controle. Com base nos resultados, pode-se recomendar que, para os parâmetros de crescimento e floração da E. coronaria de maior qualidade, as plantas podem ser pulverizadas com ANA a 100 ppm combinado com 6 g/vaso de NPK.

BACKGROUND: Branch retinal vein occlusion (BRVO) has an incidence of 0.5–1.2%. COVID-19 is associated with both venous and arterial thromboembolisms due to excessive inflammation, hypoxia, immobilization, and diffuse intravascular coagulation. AIM: The present study aims to describe our experience with BRVO in Egyptian COVID-19 patients. PATIENTS AND METHODS: The present retrospective study included 17 polymerase chain reaction (PCR)-proven COVID-19 patients with BRVO. Data obtained from the studied patients included detailed history taking. In addition, patients were diagnosed with BRVO based on a comprehensive ophthalmic evaluation, including logMAR Best-corrected visual acuity assessment, slit-lamp bio-microscopy, fundoscopy, fundus fluorescein angiography, and optical coherence tomography macular assessment. RESULTS: The present study included 17 PCR-proven COVID-19 patients with BRVO. They comprised 9 males (52.9%) and 8 females (47.1%) with an age of 52.8 ± 13.3 years. Fundus examination revealed BRVO as superior temporal in 9 patients (52.9%), inferior temporal in 5 patients (29.4%), superior nasal in 2 patients (11.8%), and inferior nasal in 1 patient (5.9%). The reported retinal thickness was 355.7 ± 41.7 μm. In addition, fundus fluorescein angiography identified ischemic changes in 2 patients (11.8%). CONCLUSION: BRVO is a rare severe complication of COVID-19 infection. In patients with proven or suspected infection with a diminution of vision, there should be high suspicion of BRVO and prompt full-scale ophthalmological examination to exclude the condition.

Behçet disease (BD) is a rare chronic relapsing-remitting inflammatory systemic vasculitis. BD patients were reported to have marked acceleration of subclinical atherosclerosis (SCA). Endocan is a soluble proteoglycan mainly secreted by the activated endothelium. The present study aimed to assess the relation between serum endocan levels and SCA in BD patients.The study included 40 adult BD patients in addition to twenty age- and sex-matched healthy controls. BD was diagnosed according to International Study Group criteria. Upon recruitment, all participants were subjected to careful history taking and thorough clinical examination. BD activity was assessed using Behçet Syndrome Activity Score. Measurement of serum endocan was performed using quantitative double-antibody sandwich ELISA kit. CIMT measurement was done using B-mode ultrasound.Comparison between patients and controls regarding serum endocan levels revealed significantly higher endocan levels in BD patients [median (IQR): 155.0 (69.3-610.0) versus 73.8 (51.9-94.6)]. Using ultrasound assessment, SCA was found in 14 BD patients (35.0%). Comparison between patients with SCA and patients without regarding the clinical and laboratory data revealed that the former group had significantly higher CRP [median (IQR): 36.5 (26.8-43.5) versus 21.0 (11.8-26.8) mg/dL, p0.001] and endocan [median (IQR): 622.0 (107.4-974.8) versus 104.5 (64.0-342.0) mg/dL, p = 0.004] levels. Logistic regression analysis recognized endocan [OR (95% CI): 1.0 (1.0-1.012), p0.035] levels as significant predictor of SCA in multivariate analysis.The present study identified the clinical value of serum endocan levels as a possible early marker of vascular involvement in BD patients.

Background: Along with canalicular or nasolacrimal duct blockage, punctum stenosis is one of the most common causes of epiphora. The purpose of the study was to investigate the prevalence of punctal occlusion outlining their presentation varieties and etiological factors. Methods: This cross-section observational study conducted on 50 patient suffering from epiphora. Patients were divided into two groups: single cause(N=19) and combination of causes (N=31). Every patient underwent: taking of the history, examination (examination of the eyelids, lid closure and lagophthalmos), evaluation of the punctum (by usage slit light for visibility, appearance and the occurrence of inflammation or oedema). Schirmer, I test used for ocular surface examination. Results: Occlusion was significantly higher in single cause than combination of causes while stenosis was significantly lower in single cause than combination of causes groups. Grades of stenosis were significantly different between the two groups. Schirmer test, lower tear meniscus height, and side of lesion were insignificantly different between study groups. Conclusions: Punctal stenosis was an extremely frequent finding in individuals suffering from epiphora. Age tended to augment the prevalence of punctal stenosis, and many patients accompanied by post-cataract surgery combined with blepharitis then topical anti-glaucoma eye drops with recurrent conjunctivitis were most common association with punctal stenosis patients who had combination of causes.

Background Identifying predictive factors of the cochlear implant outcomes in pediatric patients is critical in guiding tailored rehabilitation programs. The study aimed to assess cochlear implant outcomes, identify predictors, and highlight decision-making factors and barriers to quality care. Methods This cross-sectional study included parents of children who received unilateral cochlear implants for bilateral severe- to- deep sensorineural hearing loss. Inclusion criteria were age ≤ 5 years and intelligence quotient (IQ) Scores ≥ 85, A pre-designed structured questionnaire was used to collect data from parents/guardians of the children attending follow-up. The Arabic validated Glasgow Children Benefit Inventory score was used to assess the health-related quality of life (QOL) after intervention. Results The quality of life (QOL) score (outcome) after surgery was positive in all cases. Multivariate analysis showed that the site of operation (Bahtim hospital and Ain Shams Hospital [AOR(95% confidence interval CI), 5.7 (1.4–23), 5 (1.4–17.9), p = 0.015, 0.013, respectively]), education of the father (university/postgraduate [AOR (95% CI): 5 (1.4–17.9), p = 0.013]), the parents’ expectation that their child would be able to participate in regular classroom activities [AOR (95% CI): 8.9 (3.7–21.3), p p = 0.013, 0.001, ≤ 0.001, respectively] are significant independent predictors of good outcome. Conclusion All parents expressed a positive change in their child’s QOL. Almost all parents of children with cochlear implants face many barriers in obtaining quality healthcare services for their children. Parents, especially those with lower schooling, should receive good counselling to increase their confidence in their children’s capabilities and maximize benefits of regular follow-up. Improving the quality of healthcare centers is recommended.

Hereditary spinocerebellar degenerations (SCDs) is an umbrella term that covers a group of monogenic conditions that share common pathogenic mechanisms and include hereditary spastic paraplegia (HSP), cerebellar ataxia, and spinocerebellar ataxia. They are often complicated with axonal neuropathy and/or intellectual impairment and overlap with many neurological conditions, including neurodevelopmental disorders. More than 200 genes and loci inherited through all modes of Mendelian inheritance are known. Autosomal recessive inheritance predominates in consanguineous communities; however, autosomal dominant and X-linked inheritance can also occur. Sudan is inhabited by genetically diverse populations, yet it has high consanguinity rates. We used next-generation sequencing, genotyping, bioinformatics analysis, and candidate gene approaches to study 90 affected patients from 38 unrelated Sudanese families segregating multiple forms of SCDs. The age-at-onset in our cohort ranged from birth to 35 years; however, most patients manifested childhood-onset diseases (the mean and median ages at onset were 7.5 and 3 years, respectively). We reached the genetic diagnosis in 63% and possibly up to 73% of the studied families when considering variants of unknown significance. Combining the present data with our previous analysis of 25 Sudanese HSP families, the success rate reached 52–59% (31–35/59 families). In this article we report candidate variants in genes previously known to be associated with SCDs or other phenotypically related monogenic disorders. We also highlight the genetic and clinical heterogeneity of SCDs in Sudan, as we did not identify a major causative gene in our cohort, and the potential for discovering novel SCD genes in this population.

Background: COVID-19 pandemic affected the global population, and infection is a high risk among nurses in the gastrointestinal endoscopy unit. Endoscopy is a diagnostic procedure that involves inserting a flexible fiber-optic tube into the esophagus, stomach, or upper small intestine, depending on the degree of suspected lesions. This study aimed to evaluate the effect of educational guidelines intervention regarding COVID -19 on nurses' knowledge and precautionary practices in gastrointestinal (GIT) endoscopes. Design: A quasi-experimental design was used. Setting: The study was carried out at the gastrointestinal endoscopy unit affiliated with General Portsaid Hospitals (Al-Mabarrah Hospital, Al-Amiri Hospital, Al-Zohour Hospital, Port Fouad Hospital, and Al-Tadamon Hospital). Sample: The study included a convenient sample of all endoscopy nursing personnel (30 nurses). Three tools for data collection: (1) Demographic structured interview sheet, (2) Nurses’ Covid-19 Knowledge Questionnaire, and (3) Nurses’ Covid- 19 Precautionary Practices Checklists. Results: More than one-third of the studied nurses received training courses regarding COVID-19 before. Almost three-quarters of the studied nurses reported that their main source of information about knowledge regarding COVID-19 was doctors. There was an improvement with a highly statistically significant difference between nurse's knowledge regarding COVID -19 pre/post one month of educational intervention (P

The presence of pandemic disease as COVID-19 may increase the risk of the disease among children and can lead to several consequences such as increased fear and anxiety levels of their mothers regarding their children health. Aim: To investigate the mothers' fear and anxiety level during the COVID-19 pandemic regarding their children's health. Design: A descriptive research design was used to accomplish this study. Setting: This study was applied in Egypt at Beni-Suef City. Sample: - A total of purposive sample of 600 mothers from 5 and 25 April 2020 by using an online snowball sampling. Tools: Three online questionnaires including a structured questionnaire, fear of COVID‐19 Scale (FCV‐19S), and Corona Disease Anxiety Scale (CDAS) were used to collect data. Results: The current results revealed that women were mostly between 20 < 30 years, it was noticed that majority of mothers have experienced high fear and the majority of them had severe anxiety scores regarding their children's health. It was displayed that a significant relationship was detected between the level of (FCV‐19S) and (CDAS) scores (P =

Ihab Abdel Aziz,1 Mohamed Fawzy Alsoda,2 Tarek Mohamed Elmenofy,1 Mohamed Medhat Sakhsoukh,1 Noha Mohamed Abd el Azim,1 Amr Mahmoud Ahmed,1 Sohaila Ali Abd El-Halim,3 Sherine Salaheldin Hassan Baris,3 Yousef Ahmed Fouad,4 Ayman Mohyieldin Elghonemy,1 Heba Metwally,1 Wael Mohamed El Gendy,1 Raghdaa Ali,2 Yehia Mahmoud Basha,5 Eman Abo ElMaaty Mohamed,6 Wafaa Mohamed Amin,6 Maged Adly Naguib,1 Hazem Abdallah Elnashar1 1Department of Ophthalmology, The Memorial Institute for Ophthalmic Research, Giza, Egypt; 2Department of Pediatrics and Neonatology, Ahmed Maher Teaching Hospital, Cairo, Egypt; 3Department of Pediatrics and Neonatology, Mataria Teaching Hospital, Cairo, Egypt; 4Department of Ophthalmology, Ain Shams University Hospitals, Cairo, Egypt; 5Department of Pediatrics and Neonatology, Damanhour Teaching Hospital, Beheira, Egypt; 6Department of Pediatrics and Neonatology, El-Galaa Teaching Hospital, Cairo, EgyptCorrespondence: Hazem Abdallah Elnashar, Department of Ophthalmology, The Memorial Institute for Ophthalmic Research, Giza, 23314, Egypt, Tel +201227011043, Email Dr.hazemelnashar@gmail.comBackground: Retinopathy of prematurity (ROP) is increasing in incidence in developing nations, including Egypt. Secondary prevention requires timely detection through the development of regional screening guidelines, which should be preceded by large-scale studies to characterize the population at risk.Methods: A prospective, multicentric exploratory study that included five large tertiary institutions in an urban Egyptian setting. All infants born with gestational age (GA) < 37 weeks and/or birth weight (BW) ≤ 2000 grams were screened. More mature and heavier infants with unstable clinical course were also included. The primary outcome measure was the rate of ROP and high-risk disease occurrence in relation to underlying risk factors.Results: Of the 768 eyes (384 screened infants), 347 eyes (45.2%) had stage 1 or higher disease, and 43 eyes (5.6%) had high-risk disease. Eyes with stage 1 or higher ROP and treatment-requiring ROP had a mean (± SD) GA of 33.4 (± 2.6) weeks and 32.8 (± 3.2) weeks, and BW of 1842.3 (± 570.1) grams and 1747.6 ± (676.2) grams, respectively. Treatment-requiring eyes belonged to infants that had significantly lower GA and significantly higher prevalence of co-morbidities than non-treatment-requiring eyes.Conclusion: The incidence of ROP and high-risk disease in an urban Egyptian setting are similar to those in comparable settings elsewhere and locally. This exploratory study supports tailoring local screening criteria for ROP, and may aid the future development of national guidelines.Keywords: retinopathy of prematurity, ROP, screening, plus disease, preterm

Eman Mostafa Nassef,1 Hemmat Ahmed Elabd,2 Hala Mohamed Elzomor,2 Basma Mohamed Mohamed Ali El Nagger,2 Amira Shahin Ibrahim,2 Amal Hussein Ibrahim,1 Hend Gamal Kotb,1 Donia Ahmed Hassan,3 Rasha Elsayed Mohamed Abd ElAziz,4 Eman El Sayed Mohamed3 1Internal Medicine Department, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt; 2Rheumatology and Rehabilitation Department, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt; 3Clinical Pathology Department, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt; 4Biochemistry Department, Faculty of Medicine, Al-Azhar University, Cairo, EgyptCorrespondence: Eman Mostafa Nassef, Internal medicine Department, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt, Tel +201098002232, Email nassef.eman@yahoo.comBackground: Rheumatoid arthritis (RA) is a common systemic inflammatory disease. Collagen triple helix repeat containing-1 (CTHRC1) is a unique gene product able to reduce collagen deposition. The present study aimed to assess CTHRC1 level in RA patients and to uncover its relation to clinical, laboratory and radiological findings.Methods: The study included 60 adult RA patients. In addition, there were 60 control subjects who included patients with osteoarthritis (n = 20) and reactive arthritis (n = 20) and healthy controls (n = 20). Serum CTHRC1 levels were assessed by Enzyme-Linked Immunosorbent Assay (ELISA). Disease activity was calculated using the Disease Activity Score (DAS28-CRP). Radiological damage was evaluated using the Simple Erosion Narrowing Score (SENS).Results: There was significantly higher serum CTHRC1 levels in RA patients when compared to OA, ReA and control groups [median (IQR): 4.66 (1.68– 11.7) versus 1.88 (1.14– 2.94), 1.55 (0.98– 3.15) and 1.14 (0.85– 1.3) mg/dL, respectively, p < 0.001]. There was significantly higher CTHRC1 levels in patients with higher disease activity [median (IQR): 2.23 (1.4– 4.73) versus 6.55 (4.66– 12.0) mg/dL, p = 0.004]. Patients with higher SENS had significantly higher CTHRC1 [median (IQR): 1.99 (1.4– 4.66) versus 9.75 (4.39– 12.63) mg/dL, p < 0.001] and DAS28 [median (IQR): 4.25 (2.9– 5.2) versus 5.4 (4.65– 5.8), p = 0.01].Conclusion: Serum CTHRC1 levels are related to disease severity and radiological affection in RA patients.Keywords: rheumatoid arthritis, osteoarthritis, CTHRC1

This study aimed to study the effect of the germination process on grain quality, chemical composition for brown rice and comparing them with white rice for use it is on a commercial scale . Three rice varieties namely Sakha 104(Japonica), Giza 178(Japonica- Indica), and Giza 182(Indica) were used in this study. And the three statuses (milled rice, brown rice, and germinated brown rice). A completely randomized design in the factorial arrangement was used in this experiment to determine some cooking and eating quality characters i.e. gelatinization temperature, amylose content and elongation %, Water uptake, hardness, chemical composition: Phytic acid, total antioxidant capacity, and panel test evaluation for rice samples. The results indicated that there were significant differences in amylose content and gelatinization temperature among the three rice statuses and no significant difference in these characters with the three rice varieties under study. Germinated brown rice showed the lowest amylose content (15.58%), followed by brown rice (17.26%) and white rice (18.39%). Brown rice gave the highest temperature followed by germinated brown rice then milled rice. A maximum elongation ratio was observed in Giza178 (Japonica Indica). White rice gave the maximum elongation (47.18%) followed by germinated brown (24.56 %) then brown rice (16.08 %). Japonica rice exhibited lower hardness than indica rice. The strongest value (4.82) was recorded at brown rice, while the weakest value (3.64) was in white rice. The Indica rice variety Giza181 had the highest protein and fat%. The germinated brown rice had the highest value of protein, crude fiber, and fat (7.27, 1.98, and 2.87%, respectively), compared with compared to brown rice and white rice. White rice had lower Phytic acid (%) followed by germinated brown rice, then brown rice. Japonica rice cultivar (Sakha 104) has a higher antioxidant level than Indica rice cultivar (Giza 182)....

Thoracic surgery threatens the integrity of body, such as physical, psychological, social and spiritual aspects and may cause discomfort such as pain response and sleep disturbance. Aim: The study aimed to determine the effect of Benson's relaxation technique on reducing pain intensity, anxiety level and improving sleep quality among patients undergoing thoracic surgery. Design: A quasi experimental research design was utilized. Setting: The study was conducted in thoracic surgery department at Mansoura chest hospital and Mansoura University Hospital- chest department. Subjects: A purposive sample of 160 post thoracic surgery were recruited in this study. Tools: Four tools were used; Tool I: Assessment interview questionnaire sheet includes personal and health relevant data, Tool II: Short Form McGill Pain Questionnaire (SFMPQ), Tool III: Groningen Sleep Quality Scale (GSQS) and Tool V: Hospital Anxiety and Depression Scale (HADS). Results: There was a statistically significant effect of Benson's Relaxation Technique on reducing pain intensity, anxiety level and improving sleep quality among patients undergoing thoracic surgery. Conclusion: The study concluded that, Benson relaxation technique has a positive improvement in level of pain, quality of sleep and anxiety & depression among the study group who applied Benson's relaxation technique. Also, the most common factors that can affect the sleep quality level for those patients is the pain. Recommendation: This study recommended that, the nurses should pay more attention to Benson's relaxation technique as a simple, cheap and effective technique while taking care of post operative patients.

The optimal surgery for operable gastric carcinoma is still controversial. The aim of the current study was to assess the outcomes of D2 compared with D1 gastrectomy. This observational study included 80 patients with operable gastric cancer treated by D2 gastrectomy at Alexandria University Hospital between January 2010 and January 2016. Another 68 patients treated by D1 gastrectomy during the same period were included. Both groups were compared regarding operative mortality, morbidities, tumor recurrence, and 5-year survival rates. D2 gastrectomy had a significantly higher postoperative mortality and morbidity rates compared with D1 group (19.4% and 41.9% versus 6.3% and 18.8%). Mean number of LNs retrieved was statistically increased in D2 compared with D1 group with more frequency of adequate lymphadenectomy (LN retrieved > 15). D2 gastrectomy demonstrated significant lower recurrence and cancer-specific mortality rates compared with D1 group (18.6% and 14.5% versus 34.9% and 30.8%) with no significant difference in DFS and OS rates. Spleen-saving D2 gastrectomy showed no significant difference in early postoperative mortality with significant increase in DFS and OS compared with D1 gastrectomy (78.7% and 82% versus 61.5% and 64.6%). D2 gastrectomy had a lower recurrence and cancer-specific mortality rates than D1 gastrectomy but it had higher postoperative mortality and morbidity rates that resulted in no overall survival benefit of D2 compared with D1 gastrectomy. Spleen-saving D2 gastrectomy can be done safely in selected patients by expert surgeons without increased morbidity and mortality and better survival outcomes.

Bread wheat cross Sids 12 x Misr 3 was studied in F1, F2, F3 and F4 generations to develop promising genotypes for improvement of grain yield, rust resistance and grain quality. The two parents differed significantly for most characters under study showing sufficient variability in F2 and F3 generations to calculate the genetic parameters. The genetic variances indicated important role coupled with moderate to high broad sense heritability for most studied characters in F2 and F3 generations. Both grain filling rate and number of spikes m-2 were the most important characters in selection for high grain yield in F3 generation. Rust resistance in the two parents was controlled by one dominant gene for yellow rust, two dominant genes for leaf rust and two complementary dominant genes for stem rust. Thirty-seven families out of 100 families were superior for grain yield, but the susceptibility of the three rusts eliminated 17 families and only 20 families were resistant or moderately resistant to the three rusts. Five out of the selected 20 families had good grain quality characteristics. In F4 generation, five wheat plants characterized by an adequate resistance to the three rusts and good agronomic characters were selected for further evaluation as F5 lines.

The reseach aimed to design a learning environment based on the web and comparative ‎its effects on the level of teaching performance (performance level of teaching skills) for ‎practical education female students of Helwan university, Sadat university. The ‎researchers used the experimental method by the experimental design of the two ‎experimental groups using pre-post measurements for each group, the study was ‎conducted on a sample of physical education female students in practical education ‎schools of Cairo and Sadat in the year 2018/2019, the results indicated that learning ‎environment using the web has effective on the level of teaching performance ‎‎(performance level of teaching skills) for the two experimental groups (first, second). ‎Also, there were no differences in the level of teaching performance under research ‎between the female students of Helwan and Sadat universities in practical education ‎when using the web-based learning environment (learning environment via the web).‎

Introduction The feasibility and efficacy of emergency curative resection of complicated colorectal cancer is still controversial. This prospective study aim was to assess surgical and oncologic outcomes after emergency compared to elective curative resection of colorectal cancer. Methods 60 consecutive patients presented with complicated colorectal cancer managed by emergency surgery were included and compared to another 155 consecutive patients admitted during the same period with uncomplicated colorectal cancer managed by elective surgery. Both groups were compared regarding curative resection rate, early postoperative mortality and morbidity, 3-years tumor recurrence and survival rates. Results Complicated colorectal cancer presented at a more advanced stage with a lower resectability rate and higher postoperative mortality and morbidity rates when compared to uncomplicated ones. Emergency resection of stage I/II colorectal cancer had similar 3-years disease free, overall survival and cancer-specific mortality rates approximating elective. But, emergency resection of stage III tumors had significantly decreased 3-years disease free and overall survival rates although there was no significant increase in cancer specific mortality rate. Conclusions Complicated colonic cancers present at a more advanced stage with a lower resectability rate, and higher postoperative morbidity and mortality rates when compared with uncomplicated ones. In medically fit patients, emergency curative resection of complicated colorectal cancer could be done safely with survival outcomes approximating elective resection of uncomplicated cancer in the same stage if proper oncologic resection done by expert surgeon., Highlights • The feasibility and efficacy of emergency curative resection of complicated colorectal cancer is still controversial. • Most of previous studies were not well designed and included both curative and palliative resection. • This study compared emergency and elective curative resection regarding proper resection, tumor recurrence & survival rate. • This study revealed that emergency curative resection has ‎higher postoperative morbidity and mortality rates. • Proper emergency resection by expert surgeon has similar survival outcomes to elective resection of cancer in same stage.

The F2 and F3 populations resulting from Giza171 × Sids12 hybrid were used from 2015/2016 to 2018/2019 seasons at Sakha Agricultural Research Station to study the inheritance of some agronomic characters and resistance to rusts diseases and select new bread wheat families with high yield potential and good grain quality. Giza171 was preferable for yield and its components, while Sids12 was desirable for earliness characters. The ranges of the F2 and F3 populations went out the means of its parents for the studied characters. All characters showed moderate to high values of broad sense heritability in F2 and F3 generations. The best responsive characters to selection in F2 were No. spikes plant-1 and grain yield plant-1, while days to maturity was the least responsive character. F3 families hadhighly significant variations for all studied characters. Correlation coefficients referred that grain filling rate, followed by No. spikes m-2, then kernels weight spike-1, later the No. kernels spike-1 had the most impact on grain yield in F3 families. The resistance of yellow and leaf rusts was controlled by two dominant genes and stem rust was controlled by two complementary dominant genes. Thirteen promising families were high yielding, resistant to the three rusts and have appropriate height were selected to promote to the next advanced of segregating generations and five of them were preferable for grain quality of wheat.

Background Newborn infants have an increased sensitivity to pain and are more reactive to pain than older children and adults. Nurses play a crucial role in assessing pain, implementing and evaluating interventions to minimize neonatal pain using available resources especially nonpharmacologic techniques. Aim of the study to develop and apply an educational program on pediatric nurses regarding selected nonpharmacologic techniques to relieve pain in neonates. Research design A pre/post quasi-experimental research design was utilized in the present study. The study was carried out at Minia University for Obstetric and Pediatric and General Hospitals at neonatal care units. A convenient sample of 41 nurses was included in this study. Educational program for nurses was done through using the following data collection tools 1) Pre-designed questionnaire sheet, 2) Observation checklists sheet and 3) Educational and training program. Results It was revealed that there was an obvious increase in the total mean scores of knowledge and practice in post and follow up program phase compared with pretest phase, with a very highly significant difference (p Conclusion The education program had a significant impact on pediatric nurses' knowledge and practices regarding selected nonpharmacologic techniques to relieve pain in neonates. Recommendations A continuous training and educational program should be planned and offered on regular basis for nurses regarding nonpharmacologic techniques to relieve pain in neonates.

Purpose: To compare between micoleakage of EQUIA Forte and resin modified glass ionomer cement in primary and permanent teeth. Materials and methods: Preparation of class v cavities on the labial surface of 45 primary anterior teeth and 45 premolars was done. Teeth were then grouped and restored with EQUIA Forte, Fuji II LC, or Riva light cure. The microleakage at tooth restoration interface was done using dye penetration test with methylene blue. Scores were recorded for dye penetration depth at the occlual and cervical margins using stereomicroscope.Results: Occlusal and cervical segments of primary and permanent teeth showed that higher scores were recorded in Fugi II LC, lower scores were recorded in Riva light cure and the lowest scores were in EQUIA Forte. Chi square test revealed a significant difference between restorative materials (p=0.00). Conclusion: Among the three restorative materials, EQUIA Forte can be considered as the best material in the term of microleakage. Periodic evaluation is advised when any of the three materials are used in clinical practice.

Background: Kegel exercise role in strengthening the pelvic floor muscle in the treatment of prolapse and urinary incontinence and improve mobility and relieves pain Aim; The study aims to assess the knowledge and attitude and practices of kegel exercise among postnatal women in Al Madinah Al Munawarh, Saudi Arabia. Study design: This study utilized descriptive quantitative cross-sectional study design. Study Setting: The study was conducted of the postnatal ward in Maternity and Children's Hospital in Al Madinah Al Munawarh, Saudi Arabia. From April to December 2019. Sample: the study carried out among 152 of postpartum mothers. Tools that used in this study; Tool I: An interviewer-administered questionnaire in Arabic language was used in this study, it composed of three parts targeting the research objectives. Tool II: was concerned with knowledge of women regarding kegel exercises. Tool III: - concerned two parts: Part one: This part related to women's attitude towards kegel exercises. Part two: This part related to women's practices about kegel exercises. Results: the study found that 44.7% of the sample was in the age group 26-31 years old, 75.0% were multigravida, 85.5% had no miscarriage, 67.1% had vaginal delivery, and 50.0% have 1-3 children. 25% of the sample reported media as their source for information on kegel exercise. 62.7% of the sample had satisfactory knowledge. 72.4% were categorised as having ‘somewhat favourable’ overall attitudes towards kegel exercises. 57%of the mothers have not performed kegel exercise. 38.5% of the participants were correctly practised kegel exercise in sitting or standing position. While 29.7% was correctly practised kegel exercise in lying down position. Conclusion; Women’s knowledge concerning the kegel exercise in the postnatal period is reasonable and their attitude was favourable, but the mothers had the poor practice of kegel exercises. Recommendation; Mothers should be informed and trained to kegel exercises properly by educational courses.

Corona virus pandemic 2019 (COVID-19) lockdown has a negative psychological impact on Egyptian mothers of children with autism. As a result of social distancing, both mothers and Autism Spectrum Disorder (ASD) were not supported by face to face by care and not able to participate in external care and staying at home. Aim: The study was aimed to evaluate the effect of instructional guidelines on mothers’ anxiety regarding behavioral changes among children with autism during corona virus disease. Subjects and method: in this study quasi-experimental research design was used on a convenient sample composed of 130 mothers having children with autism residing at Sohag Governorate, Egypt. Five tools were used in this study: A self-administered questionnaire, the Adaptive Behaviour Assessment System, The ASD Behaviour Inventory, The Short Sensor and Beck Anxiety Inventory (BAI). The link of the survey using the questionnaire, the scale, and the instructional guidelines were sent to the participants' mothers through Facebook and Whats App groups. Results: The study showed an increase in repetitive and restricted behaviors among more than one-third of the participants. Mothers' anxiety level was severe before the implementation of the guideline and became low after guidelines implementation. Conclusion: The instructional guidelines were effective in reducing mothers’ anxiety regarding behavioral changes among children with autism during coronavirus pandemic outbreaks. Recommendations: Educational programs about the meanings of behavioral changes of their children, COVID -19 and its preventive measures should be taught to all mothers and psychological support is essential for them.

The optimal surgery for operable gastric carcinoma is still controversial. The aim of the current study was to assess the outcomes of D2 compared with D1 gastrectomy.This observational study included 80 patients with operable gastric cancer treated by D2 gastrectomy at Alexandria University Hospital between January 2010 and January 2016. Another 68 patients treated by D1 gastrectomy during the same period were included. Both groups were compared regarding operative mortality, morbidities, tumor recurrence, and 5-year survival rates.D2 gastrectomy had a significantly higher postoperative mortality and morbidity rates compared with D1 group (19.4% and 41.9% versus 6.3% and 18.8%). Mean number of LNs retrieved was statistically increased in D2 compared with D1 group with more frequency of adequate lymphadenectomy (LN retrieved15). D2 gastrectomy demonstrated significant lower recurrence and cancer-specific mortality rates compared with D1 group (18.6% and 14.5% versus 34.9% and 30.8%) with no significant difference in DFS and OS rates. Spleen-saving D2 gastrectomy showed no significant difference in early postoperative mortality with significant increase in DFS and OS compared with D1 gastrectomy (78.7% and 82% versus 61.5% and 64.6%).D2 gastrectomy had a lower recurrence and cancer-specific mortality rates than D1 gastrectomy but it had higher postoperative mortality and morbidity rates that resulted in no overall survival benefit of D2 compared with D1 gastrectomy. Spleen-saving D2 gastrectomy can be done safely in selected patients by expert surgeons without increased morbidity and mortality and better survival outcomes.

Introduction: Good antenatal care (ANC) reduces maternal and neonatal mortality and improves health outcomes, particularly in low-income countries. World Health Organization recommendation of initiation of antenatal care within the first four months of pregnancy and at least four antenatal care visits during the course of an uncomplicated pregnancy. Inadequate care during this time breaks a critical link in the continuum of care and affects both women and her neonate. Objectives: The aim of the study was to identify effects of antenatal care on maternal and neonatal outcomes in Women Health Hospital Subjects & Method: Three hundred parous women and their neonates conducted a comparative study. They were divided into two groups' according to parity the first group (primipara =150), and the second group (high parity=150) and divided every group into two groups the first was poor antenatal care and other was adequate antenatal care during the period from February 2017 to August 2017 using a stratified sampling. Results: Most of the primipara women had poor antenatal care (88%) but high parity (67.3%). There was the highly significant relationship between two groups. More than half were had poor antenatal care (60.3%) but less than half were adequate antenatal care. The most common complication in primipara group was eclampsia (36.4%) while in high parity group was anemia (14.3%) in poor antenatal care. The most common complication in labor was premature rupture of membrane (19.0% & 14.3%) respectively, in poor antenatal care of two groups. In primipara group, the proportion of low birth weight was 16.0% in poor antenatal care, while stillbirth was (11.0%) inadequate antenatal care also neonatal weight in Kg related to poor antenatal care and adequate antenatal care were (2.636 ± 0.659 & 3.050 ± 0.503) respectively. In high parity group, the proportion of Special Care Baby Units admission was 12.2% in poor antenatal care, while Special Care Baby Unit admission was 11.9% inadequate antenatal care also neonatal weight related to poor antenatal care and adequate antenatal care were (2.973 ± .709 & 3.081 ± 0.643) respectively. Conclusion: Good quality antenatal care promote the health of the mother and decreases the percentage of iron deficiency anemia, gestational hypertension and before term labor and promote maternal outcomes, including a reduced risk of under birth weight, preterm neonates and Special Care Baby Unit admission. Recommendations: the women should have access to good quality antenatal care. Both the woman and the neonatal are at a greater risk during pregnancy and labor. This risk can be reduced with good antenatal care and delivery by trained personnel. And awareness of the adverse impact of high parity on obstetric

Background: Calculation of medication dosages can be the challenging for nursing students. Nurse educators are able to design and develop effective methods that consider the cognitive structures and how the mind processes information to teach pediatric medication content to nursing students. The aim of the study was to compare between two teaching strategies for pediatric drug dosage calculation among under graduating nursing students Research design: A quasi-experimental study research design. Sample: Ninety nursing students in the third academic year who were studying pediatric nursing course who divided into two groups: low fidelity simulation (group I, or the study group) and traditional classroom (group II, or the comparison group). Setting: In the faculty of nursing in the South Valley University conducted this study. The tool of data collection: This study used one tool consisted of two parts: part 1 socio-demographic questionnaire and part 2: pre-dosage calculation test and post-dosage calculation test. Results: Increase mean score of knowledge among nursing students who included in the low-fidelity simulation experience (Group I) (6.69 ± 3.08; 12.71 ± 2.74) pre and posttest respectively as well as increase mean score of knowledge of nursing students who included in the traditional classroom experience (Group II) (3.20 ± 1.75; 11.58 ± 2.02) pre and posttest respectively, there was highly statistical significant p < 0.000. Illustrate that more increase the mean score of performance among nursing students who included in the low-fidelity simulation experience (Group I) than another group 2.58 ± 2.08; 12.73 ± 2.67) pre and posttest respectively. Conclusion: Lack of knowledge of basic math principles before intervention with different teaching strategies but after intervention with different teaching strategies increase the score of knowledge among nursing students who included in the low-fidelity simulation experience (Group I) equals as the score of knowledge who included in the traditional classroom experience (Group II). While increase mean score of performing of nursing students who included in the low-fidelity simulation experience (Group I) better than who included in the traditional classroom experience (Group II) posttest. Recommendations: Replicate the study with a larger sample size of students within each demographic group. Conduct a longitudinal study to measure retention of skills. Research could be conducted to see if the actual rates of dosage calculation errors are decreased in the clinical setting.

Aim: This cross-sectional study was conducted from April to July 2012 in Khartoum state, Sudan, to determine the seroprevalence of brucellosis in goats and to investigate potential risk factors associated with this disease. Materials and Methods: A total of 307 serum samples were collected from both sexes of goats in four different localities and were subjected to testing for brucellosis using rose bengal plate test (RBPT), serum agglutination test (SAT), and competitive enzyme-linked immunosorbent assay (cELISA). Results: The overall seroprevalence was 11.4% (n=35) with a 95% confidence interval (CI) ranging from 7.80 to 15.0. Out of these 35 RBPT-positive samples, the positivity of 18 and 17 were confirmed by SAT and cELISA, respectively. A significant statistical variation was observed between brucellosis seroprevalences in goats purchased from local animal markets and goats that were raised at the farm. Conversely, such significant variations were not observed among the categories of other risk factors with seroprevalences ranging from 3.0% (95% CI between 0.40 and 7.20) to 16.3% (95% CI between 10.4 and 22.3). Location (χ2=9.33, df=3, p=0.02), breed (χ2=3.52, df=1, p=0.05), herd size (χ2=6.59, df=2, p=0.03), and herd expansion (χ2=5.39, df=1, p=0.02) were associated with RBPT-positive status for brucella in the two-tailed Chi-square test. In addition, Sharq an-Nil locality and goats raised at the farm had increased odds of being RBPT positive. Conclusion: Brucellosis was detected in goats in all surveyed localities. An effort should be made to educate goat owners/herders about brucellosis as well as about the importance of vaccination.

To improve agronomic and quality in bread wheat, this experiment was performed in 2015/16 and 2016/17 seasons at Sakha Agricultural Research Station, Egypt to study performance of ten bread wheat (Triticum aestivum L.) genotypes (Giza 171, Sakha 95, Gemmeiza 12, Shandweel 1, Sids 12, Sids 14, Misr 3, Line 1, Line 2 and Line 3) and their forty-five F1 crosses were evaluated for sixteen agronomic and grain quality characters. The mean squares for genotypes, parents, crosses, parents vs. crosses, general and specific combining ability were significant for most studied characters. The ratio of general and specific combining ability was more than unity for all characters and both additive and non-additive gene effects were important in controlling the studied characters with more importance for additive effects. The best performance was detected in Sakha 95, Sids 14 and Shandweel 1 for grain yield plant-1, all parents except for Sids 12 and Giza 171 and Shandweel 1 for yellow rust, Line 1 for stem rust and Gemmeiza 12 and Sids 12 for dry gluten. The best combiners were Sakha 95, Sids 14, Giza 171 and Misr 3 for grain yield plant-1 and Giza 171, Sakha 95, Gemmeiza 12 and Shandweel 1 for wet and dry gluten. Grain yield plant-1 had positive significant correlation with grain filling rate, plant height, number of spikes plant-1 and kernel weight. The correlation of dry gluten was significant and positive with wet gluten and negative with hydration capacity percentage. Path coefficient analysis showed that the highest positive direct effect on grain yield plant-1 was obtained by grain filling period, wet gluten, days to maturity and days to heading. On the other hand, the highest negative direct effect was detected by dry gluten, hydration capacity percentage and days to anthesis. The highest positive direct effect on dry gluten was obtained by wet gluten, grain filling rate and days to maturity. Meanwhile, the highest negative direct effect on dry gluten was obtained by grain yield plant-1, hydration capacity percentage and days to anthesis. Using stepwise regression, days to heading, grain filling period and rate, kernel weight, yellow rust resistance and electrical conductivity had justified the maximum of grain yield plant-1 changes. Number of kernels spike-1, wet gluten and hydration capacity percentage had justified the maximum of dry gluten changes. Giza 171 × Misr 3, Line 1 × Line 3, Sids 12 × Misr 3, Giza 171 × Line 2, Sakha 95 × Shandweel 1, Sakha 95 × Gemmeiza 12 and Shandweel 1 × Misr 3 crosses had high yield potentiality and resistance to yellow rust and moderately susceptible to stem rust, consequently these crosses will be favorable in wheat breeding programs. Sakha 95 × Gemmeiza 12 and Sids 12 × Misr 3 were the best crosses for dry gluten and will be promising in breeding for wheat grain quality.