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Objective: This study investigates the potential for stress shielding within musculoskeletal soft tissues through analysis of stress distributions between lumbar fascial and muscle tissues via mechanical testing., Methods: Using a custom apparatus, 51 posterior thoracolumbar fascia (TLF) samples and 18 erector spinae (ES) cadaveric samples underwent tensile testing involving three loading-unloading cycles, followed by loading to 6% strain, to mechanically characterize samples. Parallel tensile testing using 20 pairs of two TLF samples, and seven pairs of TLF and ES samples was then conducted for stress distribution analysis between tissues. P<0.05 was deemed significant., Results: The TLF and ES exhibited an average elastic modulus of 150.9 MPa and 0.69 MPa, respectively. At 6% strain, parallel testing of the TLF pairs yielded an average tensile stress of 8.49 MPa and 1.7MPa (p<0.001) exhibited by the stiffer and less stiff TLF samples, respectively. Similarly, TLF-ES parallel testing resulted in average tensile stresses of 7.19 MPa and 0.079 MPa of the TLF and ES (p<0.002)., Conclusion: Results suggest elevated loading towards stiffer TLF samples relative to less stiff TLF and ES samples. In soft tissues affected by LBP, skewed stress distributions may result in the TLF withstanding the majority of stress, yielding cyclical stress shielding that may contribute to and/or promote LBP., Significance: This novel study demonstrates a potential load allocation bias towards the TLF, laying the foundation for stress shielding within lumbar musculoskeletal soft tissues affected by degenerative musculoskeletal conditions.

Introduction: The pathomechanism of low back pain (LBP) remains unknown. However, changes to mechanical properties of soft tissues affected by LBP may indicate the presence of stress shielding, which may manifest via tissue remodeling. This study investigates the potential for physiological stress shielding within the lumbar spine by examining differences within lumbar soft tissue morphology between control and LBP subjects., Methods: Through MRI, the total and functional cross-sectional area (tCSA, fCSA) and fatty infiltration (FI) of the lumbar multifidus (MF), erector spinae (ES), quadratus lumborum (QL), psoas major (PM), and thoracolumbar fascia (TLF) were measured from the L1/L2 to L5/S1 intervertebral disc levels of 69 subjects (36 LBP and 33 control subjects). Statistical analysis was conducted using Mann-Whitney U. P < 0.05 denoted significance., Results: Comparison of male LBP patients and male healthy controls yielded an increase in tCSA and fCSA within the L4/L5 PM (p < 0.01), and the L4/L5 ES (p = 0.02) and PM (p < 0.01), respectively, of LBP patients. Female LBP patients' FI compared to female controls increased within the L1/L2 MF (p = 0.03), L3/L4 MF (p = 0.04) and ES (p = 0.02), and L4/L5 QL (p = 0.01). The L3/L4 TLF also demonstrated an 8% increase in LBP subjects., Conclusion: Male patients' results suggest elevated tissue loading during motion yielding hypertrophy in the L4/L5 ES and PM fCSA, and PM tCSA. Female LBP patients' MF, ES, and PM at L3/L4 demonstrating elevated FI coupled with TLF tCSA hypertrophy may suggest irregular stress distributions and lay the foundation for stress shielding within musculoskeletal soft tissues., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2023 Elsevier Ltd. All rights reserved.)

Despite the prevalence of low back pain (LBP) in society, the pathomechanism of LBP continues to elude researchers. LBP patients have demonstrated morphological and material property changes to their lumbar soft tissues, potentially leading to irregular load sharing within the lumbar spine. This study aims to analyze potential stress shielding consequential of augmented soft tissue properties via the comparison of a healthy and LBP finite element models. The models developed in this study include the vertebrae, intervertebral discs and soft tissues from L1-S1. Soft tissue morphology and material properties for the LBP model were augmented to reflect documented clinical findings. Model validation preceded testing and was confirmed through comparison to the available literature. Relative to the healthy model, the LBP model demonstrated an increase in stress by 15.6%, with 99.8% of this stress increase being distributed towards the thoracolumbar fascia. The majority of stress skewed towards the fascia may indicate a potential stress allocation bias whereby the lumbar muscles are unable to receive regular loading, leading to stress shielding. This load allocation bias and subsequent stress shielding may potentially contribute to the progression and pathomechanism of LBP but prospective studies would be required to make that link., (© 2021. International Federation for Medical and Biological Engineering.)

Introduction: The pathomechanism of low back pain (LBP) remains unknown. Unilateral LBP patients have demonstrated ipsilateral morphological and material property changes within the lumbar soft tissues, potentially leading to asymmetric tissue loading. Through the comparison of healthy and unilateral LBP validated finite element models (FEMs), this study investigates potential stress shielding consequential of spinal tissue property augmentation., Methods: Two FEMs of the musculoskeletal system - one demonstrating healthy and unilateral LBP conditions - were developed undergoing 30-degree flexion. FEMs included the vertebrae, intervertebral discs, and soft tissues from L1-S1. Material properties selected for the soft tissues were retrieved from published literature. To reflect unilateral LBP, the paraspinal morphology was atrophied, while the tissue moduli were increased. The symptomatic thoracolumbar fascia (TLF) was uniformly increased. Validation of the models preceded testing., Results: Model validation in spinal flexion was accomplished through comparison to literature. Compared to the healthy model, the unilateral LBP multifidus (MF), longissimus thoracis (LT), and TLF exhibited average tension changes of +7.9, -5.1, and +9.3%, respectively. Likewise, the symptomatic MF, LT, and TLF exhibited tension changes of +19.0, -10.4, and +16.1% respectively, whereas the asymptomatic MF, LT, and TLF exhibited -4.0, -2.0, and +0.4% changes in tension, respectively., Conclusion: Relative to the healthy tissues, the symptomatic LBP soft tissues demonstrated a 19.5 kPa increase in stress, with 99.8% of this increase distributed towards the TLF, suggesting a load allocation bias within the symptomatic unilateral LBP tissues. Consequentially, symptomatic paraspinal muscles may be unable to withstand loading, leading to stress shielding., (Copyright © 2021 Elsevier Ltd. All rights reserved.)