Search

Purpose: To systematically review the literature to evaluate whether the bond strength of resin-based materials to enamel is affected by deproteinizing agents. Materials and Methods: This systematic review and meta-analysis was conducted according to the PRISMA statement. PubMed, ISI Web of Science, Cochrane Library, SciELO, Scopus, LILACS, IBECS, and BVS databases were screened up to December 2020. Eligibility criteria included in vitro studies that reported the effect of a deproteinizing agent applied before or after acid etching on the immediate or long-term bond strength of resin-based materials to enamel. The meta-analysis was carried out using Review Manager (version 5.3.5). A global comparison was performed with the standardized mean difference based on random-effect models at a significance level of a = 0.05. Results: A total of 23 studies were included in the meta-analysis. In all the studies, only the immediate bond strength was evaluated. The bond strength of the materials was improved by the application of NaOCl or papain prior to enamel etching with phosphoric acid (p = 0.006). None of the deproteinizing agents had a significant effect when applied after etching with phosphoric acid (p = 0.27). Conclusions: Based on in vitro studies, deproteinization with sodium hypochlorite or papain-based agents increases the immediate bond strength of resin-based materials to enamel only when used prior to phosphoric-acid etching. [ABSTRACT FROM AUTHOR]

Background: The link between dental, infective and obstructive cardiovascular diseases is debatable. Aim: To systematically review the literature to assess the association between dental conditions and development of cardiovascular disease. Methods: The systematic review was conducted following the PRISMA guidelines using PubMed (Medline), Web of Science, Scopus, EMBASE and SciELO. Results: Out of 6680 records, 82 articles were eligible for inclusion after reviewing titles and abstracts. No association between dental disease and cardiovascular disease has been observed in 10 studies while a potential link has been suggested by the remaining trials. Tooth loss and periodontitis are the main evaluated oral conditions while coronary artery disease, stroke, atherosclerosis and myocardial infarction represent the major cardiovascular events. The interaction between these two clinical entities is based on direct mechanism mediated by systemic inflammatory response, leakage of cytokines and endothelial cells invasion by oral pathogens and indirect mechanism mediated by common risk factors or confounders. Conclusions: It seems that tooth loss, periodontitis and poor oral hygiene increase the risk of atherosclerotic cardiovascular events, and subsequently oral health care professionals could contribute to public health cardiovascular control efforts. [ABSTRACT FROM AUTHOR]

Purpose: This study evaluated the effect of blood contamination and decontamination procedures performed at different stages of bonding, on the microtensile bond strength (µTBS) of an etch-and-rinse adhesive to dentin. Materials and Methods: Standardized cylindrical cavities were prepared in bovine incisors and were randomly divided into five groups, each one was treated using these experimental conditions - Control: etching-rinsing/bonding without blood contamination; Group 1: etching-rising/blood contamination/decontamination/bonding; Group 2: etching-rising/bonding/blood contamination/decontamination; Group 3: etching-rising/bonding/blood contamination/decontamination/etching-rising/bonding; and Group 4: etching-rising/blood contamination/decontamination/etching-rising/bonding. Specimens were prepared for µTBS and were evaluated both immediately and after 6 months of storage in distilled water. Results: Blood contamination significantly reduced the µTBS (P < 0.001). Groups 2 and 3 showed the lowest µTBS values, both for 24 h and 6 month aging. Conclusions: Blood contamination tested at any of the different stages of the bonding procedure showed a negative effect on the µTBS. Recovering adhesion of blood-contaminated dentin did not depend only on cleaning with distilled water. [ABSTRACT FROM AUTHOR]