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Background and Objectives: This study aims to assess white matter hyperintensities (WMHs) in pediatric migraine patients and to elucidate the pathophysiology of the disease. Materials and Methods: A total of 30 patients diagnosed with migraine and 28 healthy individuals undergoing magnetic resonance imaging (MRI) scans for various reasons in our hospital between September 2019 and April 2023 were included in the study. We evaluated the presence, number, locations, and volumetric measurement of WMHs and the relationship between hyperintensity and attack profiles in migraine patients. Results: WMHs were observed at MRI in 18 (60%) of the 30 migraine patients and in 8 (28.6%) of the 28 controls. One hyperintense lesion was detected in nine members of the patient group, two in six patients, five in one patient, eight in one patient and nine in one. One hyperintense lesion was detected in eight healthy control group members. WMHs were significantly more common in the migraine patients than in the control group (p = 0.016). There was no significant relationship between hyperintensity in migraine patients and attack duration or frequency. Analysis also revealed no significant difference in terms of hyperintensity volumes (mm3) between the study group (19.73 ± 24.26) and the control group (5.62 ± 1.83). Conclusions: This study set out to show that migraine exerts neurological effects that are not solely limited to pain by emphasizing the pronounced differences observed on the brain MRIs of migraine patients. These findings may help us achieve a better understanding of the effects of migraine on cerebral structures and functions and identify therapeutic strategies in the future.

Although fluconazole related hepatotoxicity (FRH) is rare, mortal acute hepatic necrosis and jaundice were reported in immunocompromised states such as acquired immunodeficiency syndrome (AIDS) and bone marrow transplant (BMT). We present a case of a patient with multiple sclerosis who developed hepatotoxicity with the use of a single 150 mg fluconazole tablet for fungal vaginitis, 10 days after methylprednisolone pulse treatment. Our patient’s alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels were decreased, 1200 U/L and 800 U/L, respectively, and bilirubin levels were consistent at 37 mg/dL. Artichoke which has anticholestatic and antioxidant properties was used by our patient. She consumed a 30 mg artichoke leaf extract tea 3 times a day. The bilirubin levels significantly declined at the end of the first week and all liver function tests were normalized within 2 months.

Background and Objectives: This study was performed for the purpose of assessing whether antiepileptic levetiracetam treatment produces a change in brain volumes in children with epilepsy. To that end, we compared the volumes of the basal ganglia (caudate nucleus, putamen, globus, hip-pocampus, and thalamus) at magnetic resonance imaging (MRI) before and after treatment (months 18–24) in pediatric epilepsy patients using levetiracetam. Materials and Methods: This retrospective study involved a volumetric comparison of patients presenting to the Balikesir University Medical Faculty pediatric neurology clinic between 01.08.2019 and 01.11.2023 and diagnosed with epilepsy, and who underwent cranial MRI before and 18–24 months after treatment at the radiology department. The demographic and clinical characteristics (age, sex, family history of epilepsy, type of epilepsy, and EEG features (normal, abnormal, epileptiform)) of the patients included in the study were recorded. Results: The comparison of basal ganglia volumes at cranial MRI before and at months 18–24 of treatment revealed significant differences in the left caudate nucleus, right putamen, left putamen, left globus pallidus, right thalamus, left thalamus, and right hippocampal regions. Conclusions: In conclusion, differing findings are encountered at cranial imaging in patients with epilepsy, depending on the seizure frequency, activity, and the type of antiepileptic drugs used. This study compared basal ganglia volumes on cranial MRIs taken before and 18–24 months after treatment in pediatric epilepsy patients using levetiracetam. A significant increase was observed in the volumes of basal ganglia (caudate nucleus, putamen, globus pallidus, hippocampus, and thalamus) on the MRIs of pediatric epilepsy patients using levetiracetam.

Objetivo: Investigar la viabilidad del uso de la elastografía de ondas de corte en comparación con la resonancia magnética con codificación de desplazamiento químico (RM-CDQ) para la evaluación de la degeneración grasa del músculo multífido en pacientes con dolor lumbar crónico. Método: Los músculos multífidos se evaluaron con RM-CDQ y elastografía de ondas de corte en los grupos de control y de pacientes. Se consideraron las secuencias en fase y fuera de fase en RM-CDQ, y los valores del índice de intensidad de señal y del índice de supresión de intensidad de señal; con el método de elastografía de ondas de corte se determinaron los valores de velocidad de onda de corte. Las diferencias en los valores medios de estos parámetros por nivel y por grupo de estudio se analizaron mediante la prueba t de Student. Resultados: La elastografía de ondas de corte reveló una rigidez significativamente menor en el nivel L2-3, consistente con los valores de los índices de señal que muestran una mayor infiltración grasa en la RM en el grupo de pacientes. No se encontró tal relación en el nivel L4-5 ni en el grupo de control. Conclusiones: La elastografía de ondas de corte puede ser un método prometedor para mostrar la infiltración grasa muscular a nivel L2-3 en pacientes con dolor lumbar crónico.

Introduction: Multidetector Computed Tomography (MDCT) is a widespread method for evaluating paranasal sinuses and nasal cavity in daily practice. The maxillary teeth are in field of view in a paranasal sinus CT scan and it is possible to detect dental pathologies with CT. Aim: To determine the incidence of maxillary teeth pathologies in routine paranasal sinus CT scans. Materials and Methods: A retrospective study was conducted. Consecutive 395 paranasal sinus CT scans were evaluated. All CT images were obtained with a 64 detector-CT. Patients with previous facial trauma, operation, invasive tumors and repeated exams were excluded. Detected findings were classified as “tooth loss, dental restorations or procedures and dental pathologies (carious lesions, dental developmental anomalies, periapical lesions and periodontal diseases). The proportion of findings was reported as simple percentiles. Results: Three hundred and eighty-four CT scans were included in the study. Dental restorations or procedures were determined in 129 (33.5%) patients. A total of 34 (8.8%) patients had normal teeth count and morphology. A total of 264 (64.3%) patients had at least one tooth loss. A total of 195 (51%) patients had at least one or more dental pathology. Number of dental carious lesions, dental developmental anomalies, periapical lesions and periodontal disease were 104 (27.0%), 78 (14.3%), 46 (11.9%), 44 (11.4%), respectively. Conclusion: Dental pathologies were encountered in more than half of the patients. Detecting dental pathologies may prevent tooth loss and improve oral health. The radiologist should keep in mind dental pathologies while evaluating paranasal sinus CT in daily practice.

Introduction: Computed tomography (CT) is a widespread method for evaluating head and neck pathologies. The lacrimal glands (LGs) are usually visible in routine head and neck CT scans. LG pathologies usually manifests with changes in gland sizes, so it is important to know the normal values of the LG dimensions and volume. The LG sizes may change with age, gender and race. The normal values of LG dimensions and volume in Turkish population was not reported before. Aim: The aim of this study was to evaluate the dimensions and volumes of the LGs by CT in a Turkish population. Materials and Methods: Two hundred seventeen consecutive paranasal CT scans of subjects evaluated retrospectively. Measurements of LG dimensions were performed in axial and coronal paranasal CT images. The LG volume was calculated with Aquarius software by outlining the gland in all consecutive axial images. Results: Four hundred orbits of 200 subjects were included to the study. The mean axial LG length in right and left orbits were 16.2±2.0 mm and 16.0±2.0 mm and the mean axial width of the right and left orbits were 4.1±0.7 mm and 4.0±0.7 mm. The right and left LG mean values for coronal length and width were equal 18.3 ±2.2 mm and 4.1±0.7mm respectively. The mean LG volume was 0.617±0.210 cm3 in right and 0.597±0.197 cm3 in the left orbits. There were statistically significant differences in the axial width and volume of the LG according to sides, however there was no significant difference according to gender. Age and LG measurements were negatively correlated. Conclusion: Our study may serve as a guide to determine the average values of the LG measurements in Turkish population and find out the orbital pathologies that involves the LG.