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Your search keyword '"Erlânio O, de Sousa"' showing total 3 results
Start Over Author "Erlânio O, de Sousa"
3 results on '"Erlânio O, de Sousa"'

1. Chemical Composition of the Fixed Oil of Harconia speciosa and Modulation of the Antibiotic Activity against Non-Resistant and MDR Bacterial Strains

Author

Erlânio O. de Sousa, Maria do Socorro Costa, Cícera Datiane M. Oliveira-Tintino, Carla de Fátima A. Nonato, Jacqueline C. A. Pinheiro, Henrique Douglas M. Coutinho, Irwin Rose A. de Menezes, and José Galberto M. Costa

Subjects
mangaba, fatty acid, antibacterial, aminoglycosides, Physics, QC1-999, Chemistry, QD1-999
Abstract

The species Hancornia speciosa (mangabeira) has varied potential. The bark has astringent properties, latex is used for tuberculosis, ulcers, herpes, dermatoses and warts, leaf tea is used for menstrual cramps and the root decoction to treat dislocations and hypertension. The aim of this work was to analyze the chemical composition of the fixed oil and antibacterial activities alone or in association with aminoglycosides against standard and MDR bacteria using broth microdilution assays. In the analysis of the oil by GC/MS, a high content of unsaturated fatty acids (73.46%) was identified in relation to saturated fatty acids (26.15%). Palmitic acid (22.49%) and elaidic acid (69.50%) were the main fatty acids identified. The antibacterial test results showed a more significant oil activity against Staphylococcus aureus SA–ATCC 6538 (MIC = 512 μg/mL). For other strains including standards and multidrug resistant bacteria, the oil presented MIC ≥ 1024 μg/mL. In association with antibiotics, the oil was able to improve antibacterial activity against bacterial strains. A synergic effect was observed for S. aureus SA–10, with MIC reduction of amikacin and gentamicin by 50.00 and 60.00%, respectively. The most significant association was found for Escherichia coli EC–06, with a reduction in MIC of 81.25%. The results indicate that seed oil of H. speciosa has the potential to act on bacterial resistance to aminoglycoside antibiotics.

Published
2022
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2. Characterization, antibacterial activity and antibiotic modifying action of the Caryocar coriaceum Wittm. pulp and almond fixed oil

Author

Fladson F.G. Pereira, Feitosa, Maria K. S. B., Costa, Maria Do S., Tintino, Saulo R., Fábio F.G. Rodrigues, Menezes, Irwin R. A., Coutinho, Henrique D. M., Costa, José G.M. Da, and Erlânio O. De Sousa

Abstract

In this study the physicochemical characterization of the pulp and almond fixed oil was carried out; their antibacterial activity and aminoglycoside antibiotic modifying action against standard and multiresistant Gram-positive and -negative bacteria were investigated using the broth microdilution assay. Physical properties such as moisture, pH, acidity, peroxide index, relative density and refractive index indicate stability and chemical quality of the oils. In the GC/MS chemical composition analysis, a high unsaturated fatty acid content and the presence of oleic and palmitic acids were observed in the oils. In the antibacterial assay, more significant results were obtained for Escherichia coli, while other standard and multi-resistant strains presented MIC values ≥ 1024 μg/mL. Furthermore, the fixed oils in association with antibiotics were able to significantly improve antibacterial activity against S. aureus with a reduction in MICs.

Published
2020
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3. Characterization, antibacterial activity and antibiotic modifying action of the

Author

Fladson F G, Pereira, Maria K S B, Feitosa, Maria do S, Costa, Saulo R, Tintino, Fábio F G, Rodrigues, Irwin R A, Menezes, Henrique D M, Coutinho, José G M, da Costa, and Erlânio O, de Sousa

Subjects
Staphylococcus aureus, Aminoglycosides, Fatty Acids, Malpighiales, Escherichia coli, Plant Oils, Microbial Sensitivity Tests, Gas Chromatography-Mass Spectrometry, Anti-Bacterial Agents
Abstract

In this study the physicochemical characterization of the pulp and almond fixed oil was carried out; their antibacterial activity and aminoglycoside antibiotic modifying action against standard and multiresistant Gram-positive and -negative bacteria were investigated using the broth microdilution assay. Physical properties such as moisture, pH, acidity, peroxide index, relative density and refractive index indicate stability and chemical quality of the oils. In the GC/MS chemical composition analysis, a high unsaturated fatty acid content and the presence of oleic and palmitic acids were observed in the oils. In the antibacterial assay, more significant results were obtained for

Published
2019

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