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Objective: Our aim is to evaluate the prognostic significance of isolated, preterm decreased fetal movement following normal initial full diagnostic workup. Study design: A retrospective observational study was conducted at a tertiary centre. The applied protocol was approved by the Medical Research Ethics Department of the hospital where the research was conducted. Obstetrics outcomes of preterm- and term-decreased fetal movement were compared following an initial, normal diagnostic work up. Evaluated outcomes were birth weight, mode of delivery, stillbirth rate, induction of labour, development of gestational hypertension, small for gestational age and oligohydramnios, polyhydramnios during the follow up period. Result: Obstetric complications related to placental insufficiency develops more frequently for decreased fetal movement in preterm cases with respect to that of in term cases. Following the diagnosis of decreased fetal movement, pregnancy hypertension occurred in 17% of preterm decreased fetal movement cases and in 4.7% of term decreased fetal movement cases. Fetal growth restriction developed in 6.6% of preterm decreased fetal movement and in 2.3% of term decreased fetal movement. Amniotic fluid abnormalities more frequently developed in preterm decreased fetal movement. Conclusion: Following an initial normal diagnostic workup, preterm decreased fetal movement convey a higher risk for the development of pregnancy complications associated with placental insufficiency. The patient should be monitored closely and management protocols must be developed for initial normal diagnostic workups in cases of preterm decreased fetal movement.

OBJECTIVE: Comparison of umbilical artery hemodynamic parameters in Preterm Premature Membrane Rupture of Membrane (PPROM) cases with healthy control group STUDY DESIGN: This study was performed as a retrospective cohort study at Ankara Etlik Zubeyde Hanım Maternity Hospital among 100 patients (42 with PPROM and 58 control group). RESULTS: Umbilical artery resistance index and systolic/diastolic (S/D) ratio were not different in PPROM cases and the control group (0.59 vs 0.58, 2.55 vs 2.43, respectively). Increased duration of membrane rupture had no effect on Doppler velocimetry. In patients with PPROM longer than 5 days, resistance index was 0.60, and systole/diastole ratio was 2.58; in patients with PPROM shorter than 5 days, resistance index was 0.58 and systole/diastole ratio was 2.52. There was no difference between two groups regarding Doppler findings. CONCLUSION: The presence of PPROM and the duration of PPROM have no effect on umbilical artery hemodynamic parameters.

OBJECTIVE: Evaluation of HbA1c value in diagnosis of gestational diabetes mellitus. STUDY DESIGN: This retrospective cohort study included 131 women with gestational diabetes mellitus (GDM) that were screened and diagnosed between the 24-28 weeks of gestation by two-step testing regimen in Etlik Zübeyde Hanım Women’s Health Research and Educational Hospital. Venous blood samples of these women were collected for HbA1c. One sample test was performed to test the difference between our HbA1c results and the value in the literature. RESULTS: The mean HbA1c result in our study was 5.6% (min:4.4%, max:8.0%), standard deviation was 0.5. We compared our results with the cut off value of 5.5 % that was notified for second trimester for non-diabetic pregnancies by different authors. Our HbA1c value that was 5.6% was significantly higher than the cut off values (5.5%) that was reported (p=0.008). CONCLUSION: There is an ambiguity for the threshold values of HbA1c in GDM. Further studies are needed to evaluate true cut-off values for using HbA1c for screening and diagnosing GDM.

As Hodgkin’s disease is well known as a young people neoplasia, it is rarely seen in pregnancy as other malignancies. Sometimes it is complicated with other diseases and its diagnosis is somewhat challenging. Cholestasis of pregnancy is simply diagnosed with mildly elevated liver function tests, plasma bile salts with pruritus. Our case evaluates third trimester Hodgkin’s disease complicated with pregnancy cholestasis.