350 results on '"Erythema annulare centrifugum"'
Search Results
2. Treatment Outcomes in Erythema Annulare Centrifugum: A Systematic Review.
- Author
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Geng, Ryan S.Q., Sood, Siddhartha, Lee, Andy, Waked, Jihad, Usman, Safa, Yeung, Jensen, and Mufti, Asfandyar
- Published
- 2024
- Full Text
- View/download PDF
3. Drug-induced subacute cutaneous lupus erythematosus initially diagnosed as erythema annulare centrifugum
- Author
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Arletta Kozłowska, Aleksander Obtułowicz, Aleksandra Pizun, Joanna Radzimowska-Dudek, Agata Staroń, Grzegorz Dyduch, Bartosz Obtułowicz, and Anna Wojas-Pelc
- Subjects
diagnostics ,autoimmune diseases ,drug reactions ,subacute cutaneous lupus erythematosus ,erythema annulare centrifugum ,Medicine ,Dermatology ,RL1-803 - Published
- 2024
- Full Text
- View/download PDF
4. Drug-induced subacute cutaneous lupus erythematosus initially diagnosed as erythema annulare centrifugum.
- Author
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Kozłowska, Arletta, Obtułowicz, Aleksander, Pizun, Aleksandra, Radzimowska-Dudek, Joanna, Staroń, Agata, Dyduch, Grzegorz, Obtułowicz, Bartosz, and Wojas-Pelc, Anna
- Subjects
- *
LUPUS erythematosus treatment , *PHARMACOLOGY - Abstract
Introduction: An undesirable consequence of modern medicine and pharmacology is the occurrence of drug reactions. Drug-induced cutaneous reactions account for approximately 70% of all clinical manifestations of adverse drug effects. This can be attributed to the fact that the skin, a signaling organ, is the largest body organ and exhibits significant metabolic/immunological activity. Case report: We present the case of a woman with drug-induced subacute cutaneous lupus erythematosus, primary diagnosed as erythema annulare centrifugum, who was hospitalized in the in the Department of Dermatology. Conclusions: Knowing that the prevalence of drug-induced subacute cutaneous lupus erythematosus appears to be considerably higher (70%) than previously estimated (20%), the diagnosis of drug-induced subacute cutaneous lupus erythematosus should also be considered when idiopathic subacute cutaneous lupus erythematosus is suspected, particularly if several therapeutics are utilized in patients older then 60 years. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
5. A case of erythema annulare centrifugum cleared with upadacitinib
- Author
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Valerie Foy, DO, Meagen M. McCusker, MD, and Michael J. Payette, MD, MBA
- Subjects
erythema annulare centrifugum ,JAK inhibitor ,rinvoq ,upadacitinib ,Dermatology ,RL1-803 - Published
- 2023
- Full Text
- View/download PDF
6. Evaluation of Clinicopathological Features and Associated Conditions in Erythema Annulare Centrifugum: A Retrospective Observational Analysis of 63 Patients
- Author
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Funda Erduran
- Subjects
Erythema annulare centrifugum ,clinicopathological features ,associated conditions ,Dermatology ,RL1-803 - Abstract
Introduction: Erythema annulare centrifugum (EAC) is a rare reactive disease that typically presents as annular or polycyclic erythematous lesions. There are few studies about EAC in the literature; therefore, data on the pathogenesis of the disease are limited. Objectives: We aimed to examine the demographic, clinical, pathological characteristics and associated conditions of the patients with EAC. Methods: We analyzed records of the patients with EAC who admitted to our clinic in the last four years retrospectively. Results: A total of 63 patients, 39 women and 24 men, were included in our study. The mean age of the patients was 47.8±11.2 years. The mean disease duration was 15.54±12 months. The trunk and thigh were the most commonly involved sites (49%, 33%). Associated conditions were identified in 52.3% of the patients. Infections (N = 16), malignancies (N = 6), rheumatic diseases (n=4) and drugs (n=4) were the most common precipitating factors respectively. The most common infections were superficial fungal infections and Helicobacter pylori infection. Histopathologically, 10 patients had deep type and 53 patients had superficial type EAC. We determined that the disease duration from the onset of the disease was longer (12.3 versus 16.2 months) and the number of attacks (1.2 versus 2.8 attacks) was higher in the superficial type when compared to the deep type (P = 0.042, P = 0.038). Conclusions: In our study, infections, malignancies and rheumatic diseases were among the most common etiologic factors. We would also like to draw attention to Helicobacter pylori infection as a precipitating factor which may be a novel finding.
- Published
- 2024
- Full Text
- View/download PDF
7. Skin Drug Reactions
- Author
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Tiplica, George-Sorin, Salavastru, Carmen Maria, Manole, Ionela, Tovaru, Mihaela, Smoller, Bruce, editor, and Bagherani, Nooshin, editor
- Published
- 2022
- Full Text
- View/download PDF
8. Erythema Annulare Centrifugum Mimicking Tinea Cruris on Child with Acute Myeloid Leukemia
- Author
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Citrashanty, Irmadita, Widia, Yuri, Sawitri, Zulkarnain, Iskandar, Hendaria, Made Putri, Norman, Robert A., Series Editor, Lotti, Torello M., editor, and Arcangeli, Fabio, editor
- Published
- 2022
- Full Text
- View/download PDF
9. Tocilizumab-Induced Erythema Annulare Centrifugum
- Author
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Ana Luísa João, Tomás Pessoa e Costa, Paulo Barreto, and André Lencastre
- Subjects
tocilizumab ,erythema annulare centrifugum ,rheumatoid arthritis ,adverse drug reaction ,Dermatology ,RL1-803 - Abstract
We report the case of a 42-year-old woman with rheumatoid arthritis undergoing treatment with subcutaneous tocilizumab for the past 6 months. Three days after the administration, an asymptomatic inflammatory annular plaque of 4 cm with discrete whitish scales at the inner border margin developed at the injection site in the left iliac fossa. A smaller plaque in the left groin appeared soon after. The mycological exam was negative. Histology showed a lymphoplasmacytic superficial and deep perivascular, and periadnexal, dermal infiltrate, without epidermal changes. Lesions spontaneously regressed in 4 months. The diagnosis was clinically and histologically consistent with erythema annulare centrifugum, following the exclusion of other differential diagnoses. Erythema annulare centrifugum represents a delayed-type hypersensitivity reaction generally considered idiopathic or otherwise related to numerous triggers, including drugs such as biologics. We describe the first reported case of tocilizumab-induced erythema annulare centrifugum. This case should alert dermatologists to this relatively rare and complex entity and should raise awareness to cutaneous biologic drug reactions.
- Published
- 2022
- Full Text
- View/download PDF
10. Annular Isolated Erythematous and Squamous Lesion of the Left Arm
- Author
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Lotti, Torello M., Sadoughifar, Roxanna, Lomonosov, Konstantin, Norman, Robert A., Series Editor, Lotti, Torello M., editor, Wollina, Uwe, editor, Olisova, Olga, editor, and Jafferany, Mohammad, editor
- Published
- 2022
- Full Text
- View/download PDF
11. Resolution of Erythema Annulare Centrifugum With Lung Cancer Drug Therapy: A Case Report.
- Author
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Kagabu M, Odaka H, Takita Y, Tokairin T, and Nagai T
- Abstract
Tumor-associated erythema annulare centrifugum is commonly observed in leukemia and lymphoma. In this case, we reported erythema annulare centrifugum associated with lung cancer that resolved following targeted drug therapy. A 71-year-old man with psoriasis visited our hospital with erythema annulare and pruritus. Initially, he was prescribed cyclosporine at a dose of 2.5 mg/kg suspecting a worsening of his psoriasis; however, this treatment was ineffective. Signs of paraneoplastic skin syndrome were observed, leading to a diagnosis of epidermal growth factor receptor mutation-positive lung adenocarcinoma (cT3N2M1c, stage IV, exon 19 del). After initiating osimertinib at a dose of 80 mg, the skin rash improved, and the tumor size was reduced. The final diagnosis was paraneoplastic erythema annulare centrifugum associated with lung cancer. This case highlights the potential resolution of erythema annulare centrifugum through lung cancer therapy, emphasizing the importance of considering lung cancer differential diagnosis when this skin condition is present., Competing Interests: Human subjects: Consent for treatment and open access publication was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Kagabu et al.)
- Published
- 2024
- Full Text
- View/download PDF
12. Tocilizumab-Induced Erythema Annulare Centrifugum.
- Author
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João, Ana Luísa, Pessoa e Costa, Tomás, Barreto, Paulo, and Lencastre, André
- Subjects
- *
ERYTHEMA , *DRUG side effects , *RHEUMATOID arthritis - Abstract
We report the case of a 42-year-old woman with rheumatoid arthritis undergoing treatment with subcutaneous tocilizumab for the past 6 months. Three days after the administration, an asymptomatic inflammatory annular plaque of 4 cm with discrete whitish scales at the inner border margin developed at the injection site in the left iliac fossa. A smaller plaque in the left groin appeared soon after. The mycological exam was negative. Histology showed a lymphoplasmacytic superficial and deep perivascular, and periadnexal, dermal infiltrate, without epidermal changes. Lesions spontaneously regressed in 4 months. The diagnosis was clinically and histologically consistent with erythema annulare centrifugum, following the exclusion of other differential diagnoses. Erythema annulare centrifugum represents a delayed-type hypersensitivity reaction generally considered idiopathic or otherwise related to numerous triggers, including drugs such as biologics. We describe the first reported case of tocilizumab-induced erythema annulare centrifugum. This case should alert dermatologists to this relatively rare and complex entity and should raise awareness to cutaneous biologic drug reactions. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
13. Erythema annulare centrifugum-type eruption in a patient undergoing cancer vaccine immunotherapy
- Author
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Tadros, Joseph and Rahnama-Moghadam, Sahand
- Subjects
immunotherapy ,immune related adverse events ,erythema annulare centrifugum ,sipuleucel-T - Abstract
Sipuleucel-T is a cellular immunotherapy approved for the treatment of metastatic castration-resistant prostate cancer. We report a patient developing an immune related adverse effect from sipuleucel-T drug-induced erythema annulare centrifugum-like eruption. A brief review of the mechanism and implications of this eruption are also included.
- Published
- 2018
14. Refractory erythema annulare centrifugum treated with apremilast
- Author
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Michelle S. Lee, BA, Nikolai Klebanov, MD, Daniel Yanes, MD, and Robert Stavert, MD, MBA
- Subjects
apremilast ,erythema annulare centrifugum ,treatment ,Dermatology ,RL1-803 - Published
- 2021
- Full Text
- View/download PDF
15. Annually Recurring Erythema Annulare Centrifugum: A New Case Series with Review of the Literature
- Author
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Martina Maurelli, Paolo Gisondi, Chiara Colato, and Giampiero Girolomoni
- Subjects
annually recurring erythema annulare centrifugum ,erythema annulare centrifugum ,treatment ,Dermatology ,RL1-803 - Abstract
Annually recurring erythema annulare centrifugum (AR-EAC) is a rare variant, characterized by typical annular plaques recurring in the same period of the year. We describe 5 new cases and present a review of the literature. Patients were 3 females and 2 males with an age range of 25–55 years. Multiple annular plaques were located at the thighs in 4 patients and the neck in one patient. In 1 patient, a single lesion was present. Plaques were recurring in summer in 3 cases; in 1 case, in spring; and another patient, in winter since 3–4 years. Lesions were self-healing in few days or weeks. Histologically, the epidermis presented mild acanthosis with patchy spongiosis, slight parakeratosis, and mild exocytosis. There was a perivascular lympho-histiocytic infiltrate of variable intensity in the superficial dermis, with occasional eosinophils. In 1 case, the inflammatory infiltrate reached the deep dermis. Mucin deposition was absent. Phenotyping studies in 1 case revealed a predominance of T cells, with a small B-cell component. Moreover, a moderate number of CD123+ plasmacytoid dendritic cells and CD1a+ dendritic cells were noted. Fourteen cases of AR-EAC have been published previously. Collectively, patients’ age ranged from 16 to 83 years, with a mean age of 47 years and a disease duration of 1–30 years. Lesions affected more frequently extremities and recurred most commonly in summer. Patients were all in good general health. Topical corticosteroids were the mainstay of treatment. AR-EAC is a benign disorder, the nature of which remains enigmatic.
- Published
- 2021
- Full Text
- View/download PDF
16. Erythema annulare centrifugum in a case of chronic myeloid leukemia
- Author
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Prabhat Agrawal, Amit Kumar, Nikhil Pursnani, Geetika Agarwal, and Satyanand Sathi
- Subjects
cml ,erythema annulare centrifugum ,paraneoplastic erythema annulare centrifugum eruptions ,Medicine - Abstract
Chronic myeloid leukemia (CML), BCR-ABL1-positive, is classified as a myeloproliferative neoplasm predominantly composed of proliferating granulocytes and determined to have the Philadelphia chromosome/translocation t (9;22)(q34;q11.2). Skin is said to be the mirror to systemic diseases, with skin manifestations ranging from nonspecific cutaneous lesions to specific lesions. The cutaneous manifestations of CML are generally reddish-brown to violaceous papules and nodules, indurated or hemorrhagic plaques, perifollicular acneiform papules, bullae, and palpable purpura. Other unusual manifestations could be erythema nodosum, pyoderma gangrenosum, erythema annulare centrifugum, and so on. Here we present a case of a 50-year-old woman with a history of recurrent pruritic skin lesions and erythema annulare centrifugum as the presenting complaint of CML.
- Published
- 2022
- Full Text
- View/download PDF
17. Výsev eflorescencí u transgender ženy.
- Author
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Nevrlá, Jindřiška
- Subjects
SEX (Biology) ,HORMONE therapy ,GENDER identity ,CUTANEOUS manifestations of general diseases ,GENDER dysphoria - Abstract
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- Published
- 2022
- Full Text
- View/download PDF
18. Recurrent Erythema Annulare Centrifugum due to Influenza Type A
- Author
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Luca Ena, Vittorio Mazzarello, Marco Ferrari, and Pasquale Ena
- Subjects
erythema annulare centrifugum ,influenza ,paracetamol ,cytomegalovirus ,cell-mediate immunity ,Dermatology ,RL1-803 - Abstract
Erythema annulare centrifugum (EAC) is a rare erythema characterized by erythematous and urticarial papules or annular plaques that enlarges centrifugally. The lesions usually involve the thighs and the legs. Several disorders are occasionally associated with EAC, infections, including mycoses, bacteria, or viruses and drugs have also been regarded as possible causes of this eruption. We present a 42-year-old dark-skinned woman affected by recurrent EAC that appeared secondary to influenza type A (H1N1). Histopathology showed a superficial form of EAC. In our case, a previous cytomegalovirus and Epstein-Barr virus (EBV) infection were identified and no underlying other diseases were found. Clarithromycin with calcipotriol betamethasone treatment was temporarily efficacious. In the last 3 years, the lesions started to appear every 2 weeks and tended to regress with local treatment after a variable period. We believe that the latent cytomegalovirus and the reactivity induced by EBV combined with influenza can determine, in our case, a cell mediate cutaneous immune response, which leads to the peculiar inflammatory disease known as EAC.
- Published
- 2021
- Full Text
- View/download PDF
19. Co-trimoxazole-induced erythema annulare centrifugum.
- Author
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Ponugoti, Sujit, Thiruveedhula, Haritha, Atluri, Swetha, and Samanthula, Haritha
- Subjects
- *
ANTI-inflammatory agents , *SKIN diseases , *ENDOCRINE diseases , *ERYTHEMA , *NOCARDIOSIS - Abstract
Erythema annulare centrifugum (EAC) is an infrequent cutaneous disease characterized by figurate erythematous eruptions that enlarge centrifugally at a rate of 1-3 mm/day with central clearing resulting in an annular or polycyclic appearance. The characteristic skin eruptions of EAC are associated with various underlying systemic disorders, including infections, autoimmune and endocrine diseases, malignancies, and the use of certain drugs like diuretics, non-steroidal antiinflammatory agents, antimalarials, gold, amitriptyline, finasteride, penicillins, and salicylates, though the causal association has not been established. Lesions usually involve the thighs, legs, and buttocks and are characterized histopathologically by dermal perivascular lymphohistiocytic infiltrate. EAC is a benign self-limited disease. A 64-year-old man with pulmonary nocardiosis, on treatment with co-trimoxazole, presented with peripherally spreading raised red-coloured eruptions over thighs, buttocks, and arms. He developed similar lesions in the past, which resolved spontaneously. Cutaneous examination revealed multiple discrete annular erythematous plaques over flexural areas, thighs and buttocks. Skin biopsy showed coat-sleeve peri-appendageal inflammatory infiltrate in the dermis. Pulmonary nocardiosis was confirmed by positive cultures from broncho-alveolar lavage and PCR. A diagnosis of erythema annulare centrifugum, deep type, possibly associated with nocardiosis and/or co-trimoxazole, was made. The lesions subsided after stopping co-trimoxazole. [ABSTRACT FROM AUTHOR]
- Published
- 2021
20. This month in JAAD Case Reports: July 2024: Roflumilast, Ruxolitinib, and a New Editor.
- Author
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Sloan, Brett
- Published
- 2024
- Full Text
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21. A 78-Year-Old Female with a Diffuse Pruritic Rash and Palmoplantar Desquamation
- Author
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Gabriel E. Molina, Melissa J. Danesh, Ruth K. Foreman, and Daniela Kroshinsky
- Subjects
mycosis fungoides ,cutaneous t-cell lymphoma ,erythema annulare centrifugum ,Dermatology ,RL1-803 - Abstract
Mycosis fungoides, the most common cutaneous T-cell lymphoma, is known to exhibit varied clinical presentations and mimic many other dermatoses. This morphological heterogeneity can often lead to initial misdiagnoses resulting in significant delays from symptom onset to diagnosis. We report a case of mycosis fungoides imitating clinical and histopathological features of erythema annulare centrifugum.
- Published
- 2020
- Full Text
- View/download PDF
22. Erythema Annulare Centrifugum mimicking tinea corporis: A Case Report
- Author
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Rahmadewi Rahmadewi and Riyana Noor Oktaviyanti
- Subjects
erythema annulare centrifugum ,tinea corporis ,itchy ,Dermatology ,RL1-803 - Abstract
Background: Erythema annulare centrifugum (EAC) is a rare cutaneous disease characterized by erythematous and violaceous annular plaques that usually involved the thighs and the legs with unknown etiology. EAC has a clinical similar to tinea corporis but different in terms of therapy. Case: A 52-year-old woman was complain redness patches on her both legs and abdomen since 2 month. Redness patches appeared suddenly. Firstly, small patch like insect bite appeared in her abdomen, but rapidly spread into her extremities especially at lower legs accompanied with itchy. She never complains about pain and burning sensation on his rash. No complain about ear, nose and throat disturbances, She has complain about toothache since 3 month ago. Physical examination showed on extremities inferior dextra and sinistra, there were erythematous macules sharply marginated that is varying in size. Regio abdomen and extremitas superior there were hyperpigmentasi macule sharply marginated that is varying in size. A potassium hydroxide microscopic, examination showed a negative result for a fungal infection. A skin biopsy was performed and the histologic examination revealed epidermis with spongiosis and in dermis with infiltration hystiosit, eosinofil and lymphosit on capiler blood vessel. The clinical and histopathological features, with a supportive history of recurrent lesions, led to the diagnosis of EAC. We give patient with dexamethasone and cetirizine, the lesions regressed spontaneously 3 months after onset. Discussion: The main differential diagnosis in our patient include tinea corporis. Histopathology of the skin lesions was classical for EAC. EAC resolves either spontaneously or once the underlying disease has been successfully treated. Systemic glucocorticoids usually suppress EAC, but recurrence is common when these drugs are stopped.
- Published
- 2019
- Full Text
- View/download PDF
23. Atypical erythema annulare centrifugum in a child with celiac disease
- Author
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Martina Votto, Maria De Filippo, Amelia Licari, Silvia Caimmi, Gian Luigi Marseglia, Shay Davidovich, Iga Slawatyniec, Sara Fraticelli, Stefania Barruscotti, and Valeria Brazzelli
- Subjects
celiac disease ,erythema annulare centrifugum ,gluten‐free diet ,pediatrics ,skin biopsy ,Medicine ,Medicine (General) ,R5-920 - Abstract
Abstract Herpetiformis dermatitis is the best characterized extraintestinal manifestation of celiac disease (CD). However, other chronic heterogeneous skin lesions have been associated with CD and should be considered in the differential diagnosis.
- Published
- 2021
- Full Text
- View/download PDF
24. Atypical erythema annulare centrifugum in a child with celiac disease.
- Author
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Votto, Martina, De Filippo, Maria, Licari, Amelia, Caimmi, Silvia, Marseglia, Gian Luigi, Davidovich, Shay, Slawatyniec, Iga, Fraticelli, Sara, Barruscotti, Stefania, and Brazzelli, Valeria
- Subjects
- *
CELIAC disease , *JUVENILE diseases , *ERYTHEMA , *GLUTEN-free diet , *DIFFERENTIAL diagnosis - Abstract
Herpetiformis dermatitis is the best characterized extraintestinal manifestation of celiac disease (CD). However, other chronic heterogeneous skin lesions have been associated with CD and should be considered in the differential diagnosis. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
25. An unusual case of erythema annulare centrifugum involving face.
- Author
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Pekmezci, Erkin, Küçükodacı, Zafer, and Kutlubay, Zekayi
- Subjects
- *
ERYTHEMA , *DIFFERENTIAL diagnosis , *DERMIS , *EPIDERMIS - Abstract
Erythema annulare centrifugum (EAC) is a reactive figurate erythematous disease characterised by gyrate and annular plaques with erythema. The disease is generally known as involving the extremities and trunk, but sparing the face. We present a young male patient with recurring annular erythematous scaly lesions on his face, frequently in a year since four years, with no systemic involvement. Histologically, in addition to slight parakeratosis and spongiosis in the epidermis, there was superficial lymphocytic and histiocytic perivascular infiltration with the classic coat sleeve appearance of EAC in the dermis. Although uncommon, we suggest EAC should be considered in the differential diagnosis of relevant lesions on face. [ABSTRACT FROM AUTHOR]
- Published
- 2021
26. Annually Recurring Erythema Annulare Centrifugum: A New Case Series with Review of the Literature.
- Author
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Maurelli, Martina, Gisondi, Paolo, Colato, Chiara, and Girolomoni, Giampiero
- Subjects
- *
LITERATURE reviews , *ERYTHEMA , *DENDRITIC cells , *EOSINOPHILS , *T cells - Abstract
Annually recurring erythema annulare centrifugum (AR-EAC) is a rare variant, characterized by typical annular plaques recurring in the same period of the year. We describe 5 new cases and present a review of the literature. Patients were 3 females and 2 males with an age range of 25–55 years. Multiple annular plaques were located at the thighs in 4 patients and the neck in one patient. In 1 patient, a single lesion was present. Plaques were recurring in summer in 3 cases; in 1 case, in spring; and another patient, in winter since 3–4 years. Lesions were self-healing in few days or weeks. Histologically, the epidermis presented mild acanthosis with patchy spongiosis, slight parakeratosis, and mild exocytosis. There was a perivascular lympho-histiocytic infiltrate of variable intensity in the superficial dermis, with occasional eosinophils. In 1 case, the inflammatory infiltrate reached the deep dermis. Mucin deposition was absent. Phenotyping studies in 1 case revealed a predominance of T cells, with a small B-cell component. Moreover, a moderate number of CD123+ plasmacytoid dendritic cells and CD1a+ dendritic cells were noted. Fourteen cases of AR-EAC have been published previously. Collectively, patients' age ranged from 16 to 83 years, with a mean age of 47 years and a disease duration of 1–30 years. Lesions affected more frequently extremities and recurred most commonly in summer. Patients were all in good general health. Topical corticosteroids were the mainstay of treatment. AR-EAC is a benign disorder, the nature of which remains enigmatic. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
27. Erythema annulare centrifugum in a case of chronic myeloid leukemia.
- Author
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Agrawal, Prabhat, Kumar, Amit, Pursnani, Nikhil, Agarwal, Geetika, and Sathi, Satyanand
- Subjects
- *
CHRONIC myeloid leukemia , *PHILADELPHIA chromosome , *ERYTHEMA nodosum , *ERYTHEMA , *ACNEIFORM eruptions , *MYELOPROLIFERATIVE neoplasms , *CHRONIC leukemia - Abstract
Chronic myeloid leukemia (CML), BCR-ABL1-positive, is classified as a myeloproliferative neoplasm predominantly composed of proliferating granulocytes and determined to have the Philadelphia chromosome/translocation t (9;22)(q34;q11.2). Skin is said to be the mirror to systemic diseases, with skin manifestations ranging from nonspecific cutaneous lesions to specific lesions. The cutaneous manifestations of CML are generally reddish-brown to violaceous papules and nodules, indurated or hemorrhagic plaques, perifollicular acneiform papules, bullae, and palpable purpura. Other unusual manifestations could be erythema nodosum, pyoderma gangrenosum, erythema annulare centrifugum, and so on. Here we present a case of a 50-year-old woman with a history of recurrent pruritic skin lesions and erythema annulare centrifugum as the presenting complaint of CML. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
28. Recurrent Erythema Annulare Centrifugum due to Influenza Type A.
- Author
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Ena, Luca, Mazzarello, Vittorio, Ferrari, Marco, and Ena, Pasquale
- Subjects
- *
INFLUENZA , *ERYTHEMA , *EPSTEIN-Barr virus , *MYCOSES , *CLARITHROMYCIN , *CYTOMEGALOVIRUSES - Abstract
Erythema annulare centrifugum (EAC) is a rare erythema characterized by erythematous and urticarial papules or annular plaques that enlarges centrifugally. The lesions usually involve the thighs and the legs. Several disorders are occasionally associated with EAC, infections, including mycoses, bacteria, or viruses and drugs have also been regarded as possible causes of this eruption. We present a 42-year-old dark-skinned woman affected by recurrent EAC that appeared secondary to influenza type A (H1N1). Histopathology showed a superficial form of EAC. In our case, a previous cytomegalovirus and Epstein-Barr virus (EBV) infection were identified and no underlying other diseases were found. Clarithromycin with calcipotriol betamethasone treatment was temporarily efficacious. In the last 3 years, the lesions started to appear every 2 weeks and tended to regress with local treatment after a variable period. We believe that the latent cytomegalovirus and the reactivity induced by EBV combined with influenza can determine, in our case, a cell mediate cutaneous immune response, which leads to the peculiar inflammatory disease known as EAC. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
29. Perivascular Dermatitis
- Author
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Billings, Steven D., Cotton, Jenny, Billings, Steven D., and Cotton, Jenny
- Published
- 2016
- Full Text
- View/download PDF
30. A 78-Year-Old Female with a Diffuse Pruritic Rash and Palmoplantar Desquamation.
- Author
-
Molina, Gabriel E., Danesh, Melissa J., Foreman, Ruth K., and Kroshinsky, Daniela
- Subjects
- *
CUTANEOUS T-cell lymphoma , *MYCOSIS fungoides , *SKIN diseases - Abstract
Mycosis fungoides, the most common cutaneous T-cell lymphoma, is known to exhibit varied clinical presentations and mimic many other dermatoses. This morphological heterogeneity can often lead to initial misdiagnoses resulting in significant delays from symptom onset to diagnosis. We report a case of mycosis fungoides imitating clinical and histopathological features of erythema annulare centrifugum. [ABSTRACT FROM AUTHOR]
- Published
- 2019
- Full Text
- View/download PDF
31. Aceclofenac-induced erythema annulare centrifugum
- Author
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Dilip Meena, Payal Chauhan, Neirita Hazarika, Naveen Kumar Kansal, and Arvind Gupta
- Subjects
Aceclofenac ,drug induced ,erythema annulare centrifugum ,Dermatology ,RL1-803 - Abstract
Erythema annulare centrifugum (EAC) is characterised by slowly enlarging annular erythematous lesions and is thought to represent a clinical reaction pattern to infections, medications, and rarely, underlying malignancy. Causative drugs include chloroquine, cimetidine, gold sodium thiomalate, amitriptyline, finasteride, etizolam etc. We present a case of 40-year-old woman who presented to us with a 10 days history of nonpruritic, peripherally growing annular erythematous eruption. She had a history of recent onset of joint pain, for which she was taking aceclofenac 90 mg once a day for 5 days prior to the onset of the rash. This was confirmed on biopsy as EAC. The rash promptly subsided after stopping the drug. We report this case as there was no previous report of aceclofenac induced EAC.
- Published
- 2018
- Full Text
- View/download PDF
32. Paraneoplastic erythema annulare centrifugum associated with mycosis fungoides
- Author
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Brian K. Link, BS Hannah J. Thompson, Vincent Liu, and Brian J. King
- Subjects
Mycosis fungoides ,medicine.medical_specialty ,EAC, erythema annulare centrifugum ,Erythema annulare centrifugum ,business.industry ,cutaneous T-cell lymphoma (CTCL) ,Cutaneous T-cell lymphoma ,CTCL, cutaneous T-cell lymphoma ,paraneoplastic erythema aunnulare centrifugum eruption (PEACE) ,Dermatology ,medicine.disease ,mycosis fungoides (MF) ,RL1-803 ,medicine ,Case Series ,MF, mycosis fungoides ,business ,erythema annulare centrifugum (EAC) ,PEACE, paraneoplastic erythema annulare centrifugum eruption - Published
- 2021
33. Centrifugally Spreading Annular Erythema as a Dermatological Indicator of Metastatic Breast Carcinoma.
- Author
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Youh J, Yamaguchi Y, and Hiraguchi E
- Abstract
Breast cancer is the leading cause of skin metastasis in women with internal malignancies. This report highlights an atypical case of cutaneous metastasis of breast cancer (CMBC) in a 66-year-old woman. Starting four months before her dermatology consultation, the patient underwent a chemotherapy regimen comprising pertuzumab, trastuzumab, and vinorelbine for right breast cancer, right axillary lymph node enlargement, and bone metastases. After commencing chemotherapy, erythematous macules appeared around her right nipple. Subsequently, the cutaneous lesions developed into annular erythematous patches around her right nipple and began to coalesce and expand to the contralateral breast. A skin biopsy revealed dysplastic cells indicative of metastasis from invasive ductal carcinoma. In addition, lymphovascular tumor cell invasion was noted in the reticular dermis. Based on these clinical progressions and histopathologic findings, a diagnosis of CMBC was made, specifically considering the possibility of inflammatory breast cancer (IBC). The patient continued the same chemotherapy regimen for 17 cycles, which improved the skin lesions, but she succumbed to breast cancer two years later. This case emphasizes the importance of considering CMBC in breast cancer patients with expanding, treatment-resistant thoracic cutaneous lesions, especially in aggressive subtypes like IBC. The diverse presentations of CMBC require thorough histopathological evaluation., Competing Interests: The authors have declared that no competing interests exist., (Copyright © 2024, Youh et al.)
- Published
- 2024
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34. Perivascular Dermatitis
- Author
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Billings, Steven D., Cotton, Jenny, Billings, Steven D., and Cotton, Jenny
- Published
- 2011
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35. Erythema annulare centrifugum preceding carcinoma larynx.
- Author
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Brzezinski, Piotr, Sousak, Masaoud, and Bimbi, Cesar
- Subjects
- *
ERYTHEMA , *SKIN diseases , *LARYNGEAL cancer - Abstract
Erythema annulare centrifugum (EAC) is characterized by annular, erythematous plaques with trailing scale. The skin lesions may be indurated or soft and may be static or spread centrifugally. It is considered to be a reactive condition with a wide variety of inciting causes but unclear pathophysiology. We describe a 62-year-old man with EAC. Since no association of EAC with concomitant bacterial or viral infections, we started diagnostics in the direction of systemic disease or cancer. Investigations confirmed carcinoma of larynx. We want to emphasize that EAC can appear many years before the onset of carcinoma. This is the first description of the ECM and carcinoma of the larynx with a long list of co-existing cancers. [ABSTRACT FROM AUTHOR]
- Published
- 2018
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36. Refractory erythema annulare centrifugum treated with apremilast
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Nikolai Klebanov, Michelle S. Lee, Robert Stavert, and Daniel A. Yanes
- Subjects
medicine.medical_specialty ,EAC, erythema annulare centrifugum ,Erythema annulare centrifugum ,treatment ,business.industry ,apremilast ,Case Report ,erythema annulare centrifugum ,Dermatology ,medicine.disease ,Refractory ,RL1-803 ,medicine ,Apremilast ,business ,medicine.drug - Published
- 2021
37. Annually Recurring Erythema Annulare Centrifugum: A New Case Series with Review of the Literature
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Paolo Gisondi, Giampiero Girolomoni, Martina Maurelli, and Chiara Colato
- Subjects
medicine.medical_specialty ,treatment ,Erythema annulare centrifugum ,annually recurring erythema annulare centrifugum ,business.industry ,Mean age ,Acanthosis ,erythema annulare centrifugum ,Dermatology ,medicine.disease ,medicine.anatomical_structure ,Case and Review ,Dermis ,RL1-803 ,medicine ,General health ,medicine.symptom ,Parakeratosis ,business ,Annually recurring erythema annulare centrifugum, Erythema annulare centrifugum, Treatment ,Variable intensity ,Spongiosis - Abstract
Annually recurring erythema annulare centrifugum (AR-EAC) is a rare variant, characterized by typical annular plaques recurring in the same period of the year. We describe 5 new cases and present a review of the literature. Patients were 3 females and 2 males with an age range of 25–55 years. Multiple annular plaques were located at the thighs in 4 patients and the neck in one patient. In 1 patient, a single lesion was present. Plaques were recurring in summer in 3 cases; in 1 case, in spring; and another patient, in winter since 3–4 years. Lesions were self-healing in few days or weeks. Histologically, the epidermis presented mild acanthosis with patchy spongiosis, slight parakeratosis, and mild exocytosis. There was a perivascular lympho-histiocytic infiltrate of variable intensity in the superficial dermis, with occasional eosinophils. In 1 case, the inflammatory infiltrate reached the deep dermis. Mucin deposition was absent. Phenotyping studies in 1 case revealed a predominance of T cells, with a small B-cell component. Moreover, a moderate number of CD123+ plasmacytoid dendritic cells and CD1a+ dendritic cells were noted. Fourteen cases of AR-EAC have been published previously. Collectively, patients’ age ranged from 16 to 83 years, with a mean age of 47 years and a disease duration of 1–30 years. Lesions affected more frequently extremities and recurred most commonly in summer. Patients were all in good general health. Topical corticosteroids were the mainstay of treatment. AR-EAC is a benign disorder, the nature of which remains enigmatic.
- Published
- 2021
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38. Recurrent Erythema Annulare Centrifugum due to Influenza Type A
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Marco Ferrari, Vittorio Mazzarello, Luca Ena, and Pasquale Ena
- Subjects
medicine.medical_specialty ,Erythema ,Single Case ,Congenital cytomegalovirus infection ,Cytomegalovirus ,Dermatology ,Virus ,030207 dermatology & venereal diseases ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Clarithromycin ,medicine ,lcsh:Dermatology ,Calcipotriol ,Erythema annulare centrifugum ,business.industry ,Cell-mediate immunity ,lcsh:RL1-803 ,medicine.disease ,Influenza ,Paracetamol ,chemistry ,030220 oncology & carcinogenesis ,Betamethasone ,Histopathology ,medicine.symptom ,business ,medicine.drug - Abstract
Erythema annulare centrifugum (EAC) is a rare erythema characterized by erythematous and urticarial papules or annular plaques that enlarges centrifugally. The lesions usually involve the thighs and the legs. Several disorders are occasionally associated with EAC, infections, including mycoses, bacteria, or viruses and drugs have also been regarded as possible causes of this eruption. We present a 42-year-old dark-skinned woman affected by recurrent EAC that appeared secondary to influenza type A (H1N1). Histopathology showed a superficial form of EAC. In our case, a previous cytomegalovirus and Epstein-Barr virus (EBV) infection were identified and no underlying other diseases were found. Clarithromycin with calcipotriol betamethasone treatment was temporarily efficacious. In the last 3 years, the lesions started to appear every 2 weeks and tended to regress with local treatment after a variable period. We believe that the latent cytomegalovirus and the reactivity induced by EBV combined with influenza can determine, in our case, a cell mediate cutaneous immune response, which leads to the peculiar inflammatory disease known as EAC.
- Published
- 2021
39. A case of erythema annulare centrifugum cleared with upadacitinib.
- Author
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Foy V, McCusker MM, and Payette MJ
- Abstract
Competing Interests: Valerie Foy, DO: None. Meagen McCusker, MD: Abbvie (Consultant, Speaker). Michael Payette, MD, MBA: Abbvie (Consultant, Speaker).
- Published
- 2023
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40. Approaching Target and Targetoid Eruptions in Inpatient Dermatology
- Author
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John Trinidad, Alexander M Cartron, Benjamin H. Kaffenberger, and Alecia Blaszczak
- Subjects
medicine.medical_specialty ,Erythema gyratum repens ,Erythema annulare centrifugum ,business.industry ,Dermatology ,medicine.disease ,Drug eruption ,Subacute cutaneous lupus erythematosus ,030207 dermatology & venereal diseases ,03 medical and health sciences ,0302 clinical medicine ,030220 oncology & carcinogenesis ,medicine ,Erythema migrans ,Erythema multiforme ,medicine.symptom ,business ,Pigmented purpuric dermatosis ,Granuloma annulare - Abstract
To summarize the differential diagnosis and describe a clinical approach for the evaluation of target and targetoid lesions in hospitalized patients. Important diagnostic considerations for target and targetoid lesions in an inpatient setting include erythema multiforme, Stevens-Johnson syndrome/toxic epidermal necrolysis, mycoplasma-associated rash and mucositis, fixed drug eruption, urticaria multiforme, subacute cutaneous lupus erythematosus, and Rowell syndrome. Less frequent diagnoses may include erythema migrans, arthropod bite, erythema gyratum repens, erythema annulare centrifugum, tinea concentricum, tinea corporis, Granuloma annulare, elastolytic giant cell granuloma, cutaneous T cell lymphoma, linear IgA syndrome, pigmented purpuric dermatosis of Majocchi, hobnail hemangioma, and acute hemorrhagic edema of infancy. Morphology can be a key in initially discriminating among these entities. Classic target lesions should be distinguished from targetoid, gyrate, and annular lesions. The differential diagnosis of target and targetoid lesions in hospitalized patients is broad; however, attention to additional morphologic features, location, concomitant symptoms, mucosal involvement, histopathology, location, and progression can aid in diagnosis. Clinical evaluation should also consider patient demographics and associated systemic symptoms to elucidate the correct diagnosis.
- Published
- 2020
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41. Ring within a ring appearance: A confounding manifestation of erythema annulare centrifugum
- Author
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D. Manoharan, Vignesh Nr, Sane Roja Renuka, and Nehete Sanket Sanjay
- Subjects
medicine.medical_specialty ,integumentary system ,Erythema annulare centrifugum ,business.industry ,equipment and supplies ,Malignancy ,medicine.disease ,Cosmetic dermatology ,Dermatology ,Hypersensitivity reaction ,Long period ,Erythematous plaque ,cardiovascular system ,medicine ,Etiology ,In patient ,sense organs ,cardiovascular diseases ,business - Abstract
Erythema annulare centrifugum is one of the figurate erythemas which clinically presents by annular, polycylic, erythematous plaques which is characterized by scaling behind the progressing edge. It is considered to be a hypersensitivity reaction to an antigen. Various etiological factors like cutaneous or systemic infections, drugs, malignancy, pregnancy are considered. Hereby we report a case of erythema annulare centrifugum which was treated for long period of time considering to be a dermatophytosis. This report highlights the need to be vigilant for diagnosing this condition in patients presenting with erythematous annular plaques. Keywords: Annular plaques, Erythema Annulare Centrifugum, Dermatophytosis, Histopathology.
- Published
- 2021
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42. Uncommon Non‑Infectious Annular Dermatoses
- Author
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Martina Maurelli, Chiara Colato, Paolo Gisondi, and Giampiero Girolomoni
- Subjects
Annular lichenoid dermatitis of youth and annular erythema in Sjögren syndrome, eosinophilic annular erythema, erythema annulare centrifugum, neutrophilic figurate erythema, palpable migratory arciform erythema ,Annular lichenoid dermatitis of youth and annular erythema in Sjögren syndrome ,neutrophilic figurate erythema ,Dermatology ,eosinophilic annular erythema ,erythema annulare centrifugum ,palpable migratory arciform erythema - Abstract
Several cutaneous diseases can present with annular lesions, making a distinction by physical appearance alone challenging. They can be distinguished into infectious and non-infectious, and common and uncommon annular dermatoses. Common non-infectious diseases include granuloma annulare, urticaria, and subacute lupus erythematosus. In addition, there are rare non-infectious non-neoplastic annular dermatoses whose nosographic attribution is established, including annually recurring erythema annulare centrifugum (EAC) and annular erythema in Sjögren syndrome and others whose nosographic positioning is still debated. They are neutrophilic figurate erythema, palpable migratory arciform erythema, eosinophilic annular erythema, and annular lichenoid dermatitis of youth. Their etiopathogenesis is largely unknown, although immune-mediated mechanisms are likely involved. It is difficult to establish if they are variants of reaction patterns or separate clinic-pathological entities. In fact, EAC and annually recurring EAC may represent different aspects of the same disease. Palpable migratory arciform erythema is hardly distinguishable from EAC deep type, Jessner-Kanof disease, and lupus tumidus. Neutrophilic figurate erythema and eosinophilic figurate erythema are clinically very similar and differing only in the relative proportion of eosinophils and neutrophils.
- Published
- 2022
43. Erythema annulare centrifugum induced by COVID‐19 vaccination
- Author
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Jin-Cheol Kim, Hye One Kim, S.Y. Kang, Suh Young Lee, Boyoung Chung, and Chun-Wook Park
- Subjects
Coronavirus disease 2019 (COVID-19) ,Erythema annulare centrifugum ,business.industry ,viruses ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,Dermatology ,medicine.disease ,Virology ,Viral vector ,Vaccination ,Skin reaction ,Vaccine administration ,Pandemic ,Correspondence ,medicine ,business ,skin and connective tissue diseases ,Letter to the Editor - Abstract
With the expansion of the COVID‐19 vaccination drive, an increasing number of adverse effects are surfacing. A 74‐year‐old woman presented with multiple erythematous and itchy patches on several sites. She had no relevant medical history, apart from the first AZD1222 vaccination 1 month previously. Microscopically, epidermal changes, including mild spongiosis and parakeratosis, were observed. Tight perivascular lymphocytic infiltration (coat‐sleeve pattern) was also observed in the dermis. The final diagnosis was erythema annulare centrifugum (EAC) induced by SARS‐CoV‐2 vaccination. Based on this report, dermatologists should be aware of the possibility of EAC from the AZD1222 vaccination.
- Published
- 2021
44. A rare case of erythema annulare centrifugum resolving with narrowband ultraviolet B phototherapy
- Author
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L. Peat, M. Hayes, S. James, J. G. Caesar, K. Merriman, and J. B. Powell
- Subjects
medicine.medical_specialty ,Erythema annulare centrifugum ,business.industry ,Rare case ,Medicine ,Dermatology ,business ,medicine.disease ,Narrowband ultraviolet B phototherapy - Published
- 2021
- Full Text
- View/download PDF
45. Paraneoplastic Erythema Annulare Centrifugum Eruption (PEACE) Associated With Metastatic Colorectal Adenocarcinoma
- Author
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Emily H. Smith, Susan Zurowski, Chase A Pitchford, and Mary Elizabeth Reed Shenk
- Subjects
medicine.medical_specialty ,Colorectal cancer ,Lymphoproliferative disorders ,Dermatology ,Malignancy ,paraneoplastic syndrome ,Allergy/Immunology ,Biopsy ,Erythematous plaque ,medicine ,Figurate erythema ,erythema and urticaria/figurate erythemas ,cutaneous signs of disease ,annular erythema ,medicine.diagnostic_test ,Erythema annulare centrifugum ,business.industry ,General Engineering ,cancer and oncology ,medicine.disease ,clinical dermatology ,Oncology ,Etiology ,pathology ,business - Abstract
Erythema annulare centrifugum (EAC) is a figurate erythema presenting with annular, erythematous plaques with a trailing scale. It is considered a hypersensitivity reaction to a variety of antigens and is associated with multiple underlying causes including malignancy. Malignancy-associated EAC is termed paraneoplastic erythema annulare centrifugum eruption (PEACE). Although a specific etiology has yet to be elucidated, this form of EAC is likely to occur due to cytokine and/or antigen stimulation from an underlying malignancy. PEACE is primarily associated with lymphoproliferative disorders and rarely solid tumors. Our report discusses a case of PEACE associated with metastatic colorectal adenocarcinoma. On presentation to our clinic, the patient had developed a migratory annular eruption over a year. His review of symptoms was positive for signs of underlying malignancy, including weight loss and recent lower vertebral fracture. A biopsy of his annular lesion revealed a non-specific pityriasiform dermatitis. A vertebral biopsy uncovered a diagnosis of metastatic colorectal cancer. At that time, clinicopathologic correlation allowed us to reach the diagnosis of PEACE.
- Published
- 2021
46. Erythema annulare centrifugum: a rare case report
- Author
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Khairuddin Djawad, Rina Munirah Bulqini, and Farida Tabri
- Subjects
Male ,medicine.medical_specialty ,Urticaria ,medicine.medical_treatment ,Dermatology ,Lesion ,Erythematous plaque ,Medicine ,Humans ,Buttocks ,Skin ,Erythema annulare centrifugum ,business.industry ,Pruritus ,Skin Diseases, Genetic ,Middle Aged ,medicine.disease ,Symptomatic relief ,Infectious Diseases ,medicine.anatomical_structure ,Erythema ,Abdomen ,Antihistamine ,medicine.symptom ,business ,Rare disease - Abstract
Erythema annulare centrifugum (EAC) is a rare skin disease that is thought to be caused by interactions between inflammatory cells, mediators, and foreign antigen substances. It typically starts as erythematous macules or urticarial papules that enlarge peripherally to form an arcuate or polycyclic plaque. Symptomatic relief is the main therapy for this disease because no effective treatment is yet available. We report the case of a 50-year-old male with reddish pruritic patches on both arms, around the thighs, on the abdomen, and on the buttocks. The complaint started 3 years prior to treatment and often recurred. Fungal examination was negative, and histopathological examination supported a diagnosis of EAC. The patient was prescribed a topical corticosteroid, topical antifungal, and antihistamine. Although the lesion only showed minimal improvement, the patient experienced significant reduction in pruritus with no occurrence of new lesions. Despite being a rare disease, EAC must be considered when encountering an annular erythematous plaque.
- Published
- 2021
47. Erythema annulare centrifugum triggered by SARS‐CoV‐2 infection
- Author
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María Teresa Fernández-Figueras, A Altemir, N Setó-Torrent, and M Iglesias-Sancho
- Subjects
Livedo ,medicine.medical_specialty ,2019-20 coronavirus outbreak ,Erythema ,Coronavirus disease 2019 (COVID-19) ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,Dermatology ,Letters To The Editor ,Desquamation ,Erythematous plaque ,medicine ,Humans ,skin and connective tissue diseases ,Letter to the Editor ,integumentary system ,Erythema annulare centrifugum ,SARS-CoV-2 ,business.industry ,COVID-19 ,Skin Diseases, Genetic ,medicine.disease ,Infectious Diseases ,medicine.symptom ,business - Abstract
Erythema annulare centrifugum (EAC) is a reactive phenomenon of the skin that has been reported to occur in association with numerous conditions, including infections.1 It commonly presents with annular, erythematous plaques with a fine desquamation in the inner portion of the advancing edge.2 In the last year, a wide spectrum of cutaneous manifestations has been associated with SARS-CoV-2 infection, including acral areas of erythema with vesicles or pustules, other vesicular eruptions, urticarial lesions, maculopapular eruptions and livedo or necrosis.3,4.
- Published
- 2021
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48. An Unexpected Innocent Complication Associated with Azacitidine Treatment of Myelodysplastic Syndrome: Erythema Annulare Centrifugum
- Author
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Esra Turan Erkek and Sevgi Kalayoğlu Beşışık
- Subjects
erythema annulare centrifugum ,azacitidine ,myelodysplastic syndrome ,Diseases of the blood and blood-forming organs ,RC633-647.5 - Published
- 2016
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49. Exclusive palmoplantar maculopatchy lesions in a patient of secondary syphilis
- Author
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Jalpa Patel, Trisha Patel, Rita V Vora, and Aishni Shah
- Subjects
Sexually transmitted disease ,medicine.medical_specialty ,Treponema ,Discoid lupus erythematosus ,Erythema annulare centrifugum ,biology ,business.industry ,medicine.disease ,biology.organism_classification ,Dermatology ,Rash ,Pityriasis rosea ,medicine ,Syphilis ,medicine.symptom ,business ,Granuloma annulare - Abstract
Syphilis, sexually transmitted disease which is caused by spirochete bacterium, Treponema pallidum. It presents with a spectrum of lesions and the signs and symptoms of syphilis vary depending on which of the four stages it presents. One needs a high level of clinical suspicion and keen history taking are required to identify the underlying syphilis, which is very commonly masked as some other cutaneous condition. Many different skin diseases may have lesions with a annular maculo-papular erythematous morphology and scaling, e.g., pityriasis rosea of Gibert, actinic porokeratosis, erythema annulare centrifugum, granuloma annulare, subacute or discoid lupus erythematosus and certain annular variants of psoriasis. 1 Some of these also have palmo-plantar involvement where these need to be differentiated from from the rash of secondary syphilis. The present article addresses a case of solely palmoplantar hyperpigmented lesion without any clinical evidence of secondary syphilis. Keywords: Hyperpigmentation, Secondary Syphilis, Treponema Pallidum.
- Published
- 2020
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50. Erythema Papulosa Semicircularis Recidivans: A New Entity or a Subtype of Erythema Annulare Centrifugum?
- Author
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Celia Requena, Beatriz Llombart, and E. Bernia
- Subjects
medicine.medical_specialty ,Histology ,Erythema annulare centrifugum ,Erythema ,business.industry ,Medicine ,Dermatology ,medicine.symptom ,business ,medicine.disease ,Pathology and Forensic Medicine - Published
- 2020
- Full Text
- View/download PDF
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