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2. Abstract 4136632: Impact of Postoperative Atrial Fibrillation on Long-term Clinical Outcomes in Patients after Coronary Artery Bypass Grafting

Author

Kuroda, Yuki, Shiomi, Hiroki, Morimoto, Takeshi, Hirao, Shingo, Tsubota, Hideki, Matsuo, Takehiko, Uehara, Kyokun, Esaki, Jiro, Shimamoto, Takeshi, Kanemitsu, Hideo, Tsuneyoshi, Hiroshi, Kanemitsu, Naoki, Iwakura, Atsushi, Tamura, Nobushige, Furukawa, Yutaka, Kadota, Kazushige, Ando, Kenji, Ohno, Nobuhisa, Komiya, Tatsuhiko, Kimura, Takeshi, and Minatoya, Kenji

Published
2024
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3. Prognostic significance of baseline low-density lipoprotein cholesterol in patients undergoing coronary revascularization; a report from the CREDO-Kyoto registry

Author

Kanenawa, Kenji, Yamaji, Kyohei, Morimoto, Takeshi, Yamamoto, Ko, Domei, Takenori, Hyodo, Makoto, Shiomi, Hiroki, Furukawa, Yutaka, Nakagawa, Yoshihisa, Kadota, Kazushige, Watanabe, Hirotoshi, Yoshikawa, Yusuke, Tada, Tomohisa, Tazaki, Junichi, Ehara, Natsuhiko, Taniguchi, Ryoji, Tamura, Toshihiro, Iwakura, Atsushi, Tada, Takeshi, Suwa, Satoru, Toyofuku, Mamoru, Inada, Tsukasa, Kaneda, Kazuhisa, Ogawa, Tatsuya, Takeda, Teruki, Sakai, Hiroshi, Yamamoto, Takashi, Tambara, Keiichi, Esaki, Jiro, Eizawa, Hiroshi, Yamada, Miho, Shinoda, Eiji, Nishizawa, Junichiro, Mabuchi, Hiroshi, Tamura, Nobushige, Shirotani, Manabu, Nakayama, Shogo, Uegaito, Takashi, Matsuda, Mitsuo, Takahashi, Mamoru, Inoko, Moriaki, Kanemitsu, Naoki, Tamura, Takashi, Ishii, Katsuhisa, Nawada, Ryuzo, Onodera, Tomoya, Ohno, Nobuhisa, Koyama, Tadaaki, Tsuneyoshi, Hiroshi, Sakamoto, Hiroki, Aoyama, Takeshi, Miki, Shinji, Tanaka, Masaru, Sato, Yukihito, Yamazaki, Fumio, Hanyu, Michiya, Soga, Yoshiharu, Komiya, Tatsuhiko, Minatoya, Kenji, Ando, Kenji, and Kimura, Takeshi

Published
2024
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5. Life Expectancy of Patients With Severe Aortic Stenosis in Relation to Age and Surgical Risk Score

Author

Taniguchi, Tomohiko, Morimoto, Takeshi, Yamaji, Kyohei, Shirai, Shinichi, Ando, Kenji, Shiomi, Hiroki, Takeji, Yasuaki, Ohno, Nobuhisa, Kanamori, Norio, Yamazaki, Fumio, Koyama, Tadaaki, Kim, Kitae, Ehara, Natsuhiko, Furukawa, Yutaka, Komiya, Tatsuhiko, Iwakura, Atsushi, Shirotani, Manabu, Esaki, Jiro, Sakaguchi, Genichi, Fujii, Kosuke, Nakayama, Shogo, Mabuchi, Hiroshi, Tsuneyoshi, Hiroshi, Eizawa, Hiroshi, Shiraga, Kotaro, Hanyu, Michiya, Nakano, Akira, Ishii, Katsuhisa, Tamura, Nobushige, Higashitani, Nobuya, Kouchi, Ichiro, Yamada, Tomoyuki, Nishizawa, Junichiro, Jinnai, Toshikazu, Morikami, Yuko, Minatoya, Kenji, and Kimura, Takeshi

Published
2023
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7. Modifiers of the Risk of Diabetes for Long-Term Outcomes After Coronary Revascularization: CREDO-Kyoto PCI/CABG Registry

Author

Kimura, Takeshi, Shiomi, Hiroki, Matsuda, Mitsuo, Takeuchi, Yuzo, Mitsuoka, Hirokazu, Uegaito, Takashi, Nakagawa, Yoshihisa, Tamura, Toshihiro, Konishi, Takashi, Ootani, Seiji, Fujiwara, Hisayoshi, Takatsu, Yoshiki, Sato, Yukihito, Taniguchi, Ryoji, Kataoka, Kazuaki, Inoko, Moriaki, Nohara, Ryuji, Nakano, Kimisato, Miyamoto, Syoichi, Kunihiko, Nagai, Murakami, Tomoyuki, Takeda, Teruki, Ishida, Katsuya, Nobuyoshi, Masakiyo, Yamaji, Kyohei, Yasumoto, Hitoshi, Iwabuchi, Masashi, Ando, Kenji, Domei, Takenori, Kato, Masayuki, Tatami, Ryozo, Shirotani, Manabu, Hattori, Ryuichi, Kita, Toru, Furukawa, Yutaka, Ehara, Natsuhiko, Kihara, Yasuki, Eizawa, Hiroshi, Kato, Hiroshi, Ishii, Katsuhisa, Aoyama, Takeshi, Sakurai, Takahiro, Kawanami, Masaki, Suyama, Tamaki, Tada, Eiji, Tanaka, Masaru, Inada, Tsukasa, Uzui, Hiroyasu, Nakano, Akira, Lee, Jong-Dae, Onodera, Tomoya, Takizawa, Akinori, Ryuzo, Nawada, Shinoda, Eiji, Takahashi, Masaaki, Yamada, Miho, Horie, Minoru, Yamamoto, Takashi, Takashima, Hiroyuki, Sakai, Hiroshi, Tamura, Takashi, Toyofuku, Mamoru, Kotoura, Hajime, Miura, Akira, Takahashi, Mamoru, Matoba, Yoshiki, Takumi, Takuro, Tei, Chuwa, Hamasaki, Shuichi, Doi, Osamu, Kambara, Hirofumi, Kaburagi, Satoshi, Sakamoto, Hiroki, Tada, Tomohisa, Mitsudo, Kazuaki, Kadota, Kazushige, Tada, Takeshi, Miki, Shinji, Mizoguchi, Tetsu, Akira, Yoshida, Kaneda, Kazuhisa, Ogawa, Hisao, Sugamura, Koichi, Sugiyama, Seigo, Doyama, Kiyoshi, Araki, Makoto, Suwa, Satoru, Sakata, Ryuzo, Ikeda, Tadashi, Marui, Akira, Minatoya, Kenji, Yamazaki, Kazuhiro, Onoe, Masahiko, Ogawa, Tatsuya, Yamanaka, Kazuo, Iwakura, Atsushi, Ohno, Nobuhisa, Fujiwara, Keiichi, Hanyu, Michiya, Soga, Kinji, Matsushita, Tsutomu, Nishiwaki, Noboru, Yoshida, Yuichi, Tamura, Nobushige, Okada, Yukikatsu, Nasu, Michihiro, Koyama, Tadaaki, Nakayama, Shogo, Tanaka, Kuniyoshi, Koshiji, Takaaki, Morioka, Koichi, Shimamoto, Mitsuomi, Yamazaki, Fumio, Terai, Yasuhiko, Nishizawa, Junichiro, Aota, Masaki, Kanemitsu, Naoki, Hara, Hiroyuki, Tabata, Takafumi, Imoto, Yutaka, Yamamoto, Hiroyuki, Matsuda, Katsuhiko, Nara, Masafumi, Tsuneyoshi, Hiroshi, Komiya, Tatsuhiko, Nakajima, Hiroyuki, Esaki, Jiro, Kawasuji, Michio, Moriyama, Syuji, Tambara, Keiichi, Arimura, Sakiko, Fujino, Yumika, Hanazawa, Miya, Hibi, Chikako, Kato, Risa, Kinoshita, Yui, Kitagawa, Kumiko, Kitamura, Masayo, Kuwahara, Takahiro, Sachiko, Maeda, Miki, Izumi, Minematsu, Saeko, Nishida, Satoko, Okamoto, Naoko, Saeki, Asuka, Sasae, Hitomi, Sato, Yuki, Takahashi, Asuka, Takinami, Emi, Tezuka, Saori, Tsuda, Marina, Tsumori, Miyuki, Uchida, Yuriko, Yamamoto, Yuko, Yamauchi, Misato, Yamazaki, Itsuki, Yoshimoto, Mai, Abe, Mitsuru, Fuki, Masayuki, Hayano, Mamoru, Kato, Eri, Kato, Yoshihiro, Matsumura-Nakano, Yukiko, Nakajima, Tetsu, Nakatsuma, Kenji, Natsuaki, Masahiro, Takeji, Yasuaki, Tazaki, Junichi, Tokushige, Akihiro, Watanabe, Hiroki, Yaku, Hidenori, Yamamoto, Erika, Yamamoto, Ko, Yamashita, Yugo, Yoshikawa, Yusuke, Morimoto, Takeshi, Kato, Eri T., Imada, Kazuaki, Nishikawa, Ryusuke, Mabuchi, Hiroshi, and Soga, Yoshiharu

Published
2022
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8. Comparison of open and hybrid endovascular repair for aortic arch: a multi-centre study of 1052 adult patients.

Author

Sakamoto, Kazuhisa, Shimamoto, Takeshi, Esaki, Jiro, Komiya, Tatsuhiko, Ohno, Nobuhisa, Nakayama, Shogo, Paku, Masaki, Hidaka, Yu, Morita, Satoshi, Marui, Akira, Minatoya, Kenji, and Investigators, Advance-Kyoto

Abstract

OBJECTIVES We aimed to evaluate early and late outcomes by comparing open total arch repair and endovascular arch repair using proximal landing zone analysis in a multicentre cohort. METHODS From 2008 to 2019, patients treated surgically for aortic arch disease at 6 centres were included, excluding cases with type A aortic dissection, additional aortic root replacement and extensive aortic aneurysm. In all patients and populations with proximal landing zones 0/1 (N  = 144) and 2 (N  = 187), early and late outcomes were compared using propensity score matching. RESULTS A total of 1052 patients, including 331 (31%) and 721 (69%) patients undergoing endovascular arch repair and open total arch repair, respectively, were enrolled. After propensity score match (endovascular arch repair, 295; open total arch repair, 566), no significant difference was observed in in-hospital mortality rate (endovascular arch repair, 6.8%; open total arch repair, 6.2%; P  = 0.716). Open total arch repair was associated with a lower risk of all-cause death [log-rank test; P  = 0.010, hazard ratio (HR) 1.41 (95% confidence interval 1.17–1.71)]. The incidence of aorta-related death was higher in endovascular arch repair [Gray's test; P  = 0.030, HR; 1.44 (95% confidence interval 1.20–1.73)]. When compared to endovascular arch repair with proximal landing zone 0/1, open total arch repair was associated with lower risks of all-cause death [log-rank test; P  < 0.001, HR 2.04 (95% confidence interval 1.43–2.90)] and aorta-related death [Gray's test; P  = 0.002, HR 1.67 (95% confidence interval; 1.25–2.24)]. There was no difference in the risk of all-cause death [log-rank test; P  = 0.961, HR 0.99 (95% confidence interval 0.67–1.46)] and aorta-related death [Gray's test; P  = 0.55, HR 1.31 (95% confidence interval 1.03–1.67)] between endovascular arch repair with proximal landing zone 2 and open total arch repair. CONCLUSIONS Open total arch repair was considered the 1st choice based on early and late results; however, endovascular arch repair may be a useful option if the proximal landing zone is limited to zone 2. [ABSTRACT FROM AUTHOR]

Published
2024
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10. Coronary Revascularization in the Past Two Decades in Japan (From the CREDO-Kyoto PCI/CABG Registries Cohort-1, -2, and -3)

Author

Shiomi, Hiroki, Morimoto, Takeshi, Furukawa, Yutaka, Nakagawa, Yoshihisa, Kadota, Kazushige, Yoshikawa, Yusuke, Yamaji, Kyohei, Tada, Tomohisa, Tazaki, Junichi, Ehara, Natsuhiko, Taniguchi, Ryoji, Tamura, Toshihiro, Iwakura, Atsushi, Tada, Takeshi, Watanabe, Hirotoshi, Suwa, Satoru, Toyofuku, Mamoru, Inada, Tsukasa, Kaneda, Kazuhisa, Ogawa, Tatsuya, Takeda, Teruki, Sakai, Hiroshi, Yamamoto, Takashi, Tambara, Keiichi, Esaki, Jiro, Eizawa, Hiroshi, Yamada, Miho, Shinoda, Eiji, Nishizawa, Junichiro, Mabuchi, Hiroshi, Tamura, Nobushige, Shirotani, Manabu, Nakayama, Shogo, Uegaito, Takashi, Matsuda, Mitsuo, Takahashi, Mamoru, Inoko, Moriaki, Kanemitsu, Naoki, Tamura, Takashi, Ishii, Kazuhisa, Nawada, Ryuzo, Onodera, Tomoya, Ohno, Nobuhisa, Koyama, Tadaaki, Tsuneyoshi, Hiroshi, Sakamoto, Hiroki, Aoyama, Takeshi, Miki, Shinji, Tanaka, Masaru, Sato, Yukihito, Yamazaki, Fumio, Hanyu, Michiya, Soga, Yoshiharu, Komiya, Tatsuhiko, Ando, Kenji, Minatoya, Kenji, and Kimura, Takeshi

Published
2021
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11. Comparison of Outcomes of Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting Among Patients With Three-Vessel Coronary Artery Disease in the New-Generation Drug-Eluting Stents Era (From CREDO-Kyoto PCI/CABG Registry Cohort-3)

Author

Matsumura-Nakano, Yukiko, Shiomi, Hiroki, Morimoto, Takeshi, Yamaji, Kyohei, Ehara, Natsuhiko, Sakamoto, Hiroki, Takeji, Yasuaki, Yoshikawa, Yusuke, Yamamoto, Ko, Imada, Kazuaki, Tada, Takeshi, Taniguchi, Ryoji, Nishikawa, Ryusuke, Tada, Tomohisa, Uegaito, Takashi, Ogawa, Tatsuya, Yamada, Miho, Takeda, Teruki, Eizawa, Hiroshi, Tamura, Nobushige, Tambara, Keiichi, Suwa, Satoru, Shirotani, Manabu, Tamura, Toshihiro, Inoko, Moriaki, Nishizawa, Junichiro, Natsuaki, Masahiro, Sakai, Hiroshi, Yamamoto, Takashi, Kanemitsu, Naoki, Ohno, Nobuhisa, Ishii, Katsuhisa, Marui, Akira, Tsuneyoshi, Hiroshi, Terai, Yasuhiko, Nakayama, Shogo, Yamazaki, Kazuhiro, Takahashi, Mamoru, Tamura, Takashi, Esaki, Jiro, Miki, Shinji, Onodera, Tomoya, Mabuchi, Hiroshi, Furukawa, Yutaka, Tanaka, Masaru, Komiya, Tatsuhiko, Soga, Yoshiharu, Hanyu, Michiya, Ando, Kenji, Kadota, Kazushige, Minatoya, Kenji, Nakagawa, Yoshihisa, and Kimura, Takeshi

Published
2021
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12. Risk factors for postoperative acute pancreatitis after thoracic aortic surgery.

Author

Ueda, Ryoma, Esaki, Jiro, Tsubota, Hideki, Honda, Masanori, Kudo, Masafumi, Matsuo, Takehiko, and Okabayashi, Hitoshi

Abstract

Background: We aimed to investigate the incidence and risk factors of postoperative acute pancreatitis (PAP) following thoracic aortic surgery with circulatory arrest. Methods: One hundred fifty-two patients who underwent thoracic aortic surgery with circulatory arrest between February 2015 and March 2023 were retrospectively reviewed. Postoperative acute pancreatitis was defined as the presence of two or more of the following criteria: (1) abdominal pain, (2) postoperative amylase or lipase levels greater than three times the upper limit of normal, and (3) evidence of pancreatitis on postoperative computed tomography (CT) scan. Univariate and multivariate analyses were performed to find risk factors for PAP. Results: Nine patients (5.9%) developed PAP without mortality. All of the nine patients had elevated pancreatic enzymes and evidence of pancreatitis on CT. They improved with conservative therapy. In multivariate analysis, only cross-clamp time was found to be a significant risk factor for PAP (adjusted odds ratio, 1.04; 95% confidence interval, 1–1.08; p = 0.042). Conclusion: The incidence of PAP after thoracic aortic surgery with circulatory arrest was 5.9%, and cross-clamp time is an independent risk factor for PAP. [ABSTRACT FROM AUTHOR]

Published
2024
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13. Intermediate-term outcomes of aortic valve replacement with bioprosthetic or mechanical valves in patients on hemodialysis

Author

Nishizawa, Junichiro, Ohno, Nobuhisa, Esaki, Jiro, Ueyama, Koji, Koyama, Tadaaki, Hanyu, Michiya, Tamura, Nobushige, Komiya, Tatsuhiko, Saito, Yuhei, Kanemitsu, Naoki, Soga, Yoshiharu, Shiraga, Kotaro, Nakayama, Shogo, Nonaka, Michihito, Sakaguchi, Genichi, Nishimura, Kazunobu, Yamanaka, Kazuo, Nakatsu, Taro, Minakata, Kenji, Tanaka, Shiro, and Minatoya, Kenji

Published
2019
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16. Age and Survival After Surgical Aortic Valve Replacement in Patients with Severe Aortic Stenosis: CURRENT AS Registry

Author

Taniguchi, Tomohiko, primary, Morimoto, Takeshi, additional, Yamaji, Kyohei, additional, Shirai, Shinichi, additional, Ando, Kenji, additional, Shiomi, Hiroki, additional, Takeji, Yasuaki, additional, Ohno, Nobuhisa, additional, Kanamori, Norio, additional, Yamazaki, Fumio, additional, Koyama, Tadaaki, additional, Kim, Kitae, additional, Ehara, Natsuhiko, additional, Furukawa, Yutaka, additional, Komiya, Tatsuhiko, additional, Iwakura, Atsushi, additional, Shirotani, Manabu, additional, Esaki, Jiro, additional, Sakaguchi, Genichi, additional, Fujii, Kosuke, additional, Nakayama, Shogo, additional, Mabuchi, Hiroshi, additional, Tsuneyoshi, Hiroshi, additional, Eizawa, Hiroshi, additional, Shiraga, Kotaro, additional, Hanyu, Michiya, additional, Nakano, Akira, additional, Ishii, Katsuhisa, additional, Tamura, Nobushige, additional, Higashitani, Nobuya, additional, Kouchi, Ichiro, additional, Yamada, Tomoyuki, additional, Nishizawa, Junichiro, additional, Jinnai, Toshikazu, additional, Morikami, Yuko, additional, Minatoya, Kenji, additional, and Kimura, Takeshi, additional

Published
2022
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17. Percutaneous coronary intervention using new-generation drug-eluting stents versus coronary arterial bypass grafting in stable patients with multi-vessel coronary artery disease: From the CREDO-Kyoto PCI/CABG registry Cohort-3

Author

50728037, 30837670, 10844920, 50860582, Watanabe, Hiroki, Yamamoto, Ko, Shiomi, Hiroki, Morimoto, Takeshi, Kato, Eri, Matsumura, Yukiko, Nakatsuma, Kenji, Takeji, Yasuaki, Yaku, Hidenori, Yamamoto, Erika, Yamashita, Yugo, Yoshikawa, Yusuke, Fuki, Masayuki, Yamaji, Kyohei, Ehara, Natsuhiko, Sakamoto, Hiroki, Imada, Kazuaki, Tada, Takeshi, Taniguchi, Ryoji, Nishikawa, Ryusuke, Tada, Tomohisa, Uegaito, Takashi, Ogawa, Tatsuya, Yamada, Miho, Takeda, Teruki, Eizawa, Hiroshi, Tamura, Nobushige, Tambara, Keiichi, Suwa, Satoru, Shirotani, Manabu, Tamura, Toshihiro, Inoko, Moriaki, Nishizawa, Junichiro, Natsuaki, Masahiro, Sakai, Hiroshi, Yamamoto, Takashi, Kanemitsu, Naoki, Ohno, Nobuhisa, Ishii, Katsuhisa, Marui, Akira, Tsuneyoshi, Hiroshi, Terai, Yasuhiko, Nakayama, Shogo, Yamazaki, Kazuhiro, Takahashi, Mamoru, Tamura, Takashi, Esaki, Jiro, Miki, Shinji, Onodera, Tomoya, Mabuchi, Hiroshi, Furukawa, Yutaka, Tanaka, Masaru, Komiya, Tatsuhiko, Soga, Yoshiharu, Hanyu, Michiya, Ando, Kenji, Kadota, Kazushige, Minatoya, Kenji, Nakagawa, Yoshihisa, Kimura, Takeshi, 50728037, 30837670, 10844920, 50860582, Watanabe, Hiroki, Yamamoto, Ko, Shiomi, Hiroki, Morimoto, Takeshi, Kato, Eri, Matsumura, Yukiko, Nakatsuma, Kenji, Takeji, Yasuaki, Yaku, Hidenori, Yamamoto, Erika, Yamashita, Yugo, Yoshikawa, Yusuke, Fuki, Masayuki, Yamaji, Kyohei, Ehara, Natsuhiko, Sakamoto, Hiroki, Imada, Kazuaki, Tada, Takeshi, Taniguchi, Ryoji, Nishikawa, Ryusuke, Tada, Tomohisa, Uegaito, Takashi, Ogawa, Tatsuya, Yamada, Miho, Takeda, Teruki, Eizawa, Hiroshi, Tamura, Nobushige, Tambara, Keiichi, Suwa, Satoru, Shirotani, Manabu, Tamura, Toshihiro, Inoko, Moriaki, Nishizawa, Junichiro, Natsuaki, Masahiro, Sakai, Hiroshi, Yamamoto, Takashi, Kanemitsu, Naoki, Ohno, Nobuhisa, Ishii, Katsuhisa, Marui, Akira, Tsuneyoshi, Hiroshi, Terai, Yasuhiko, Nakayama, Shogo, Yamazaki, Kazuhiro, Takahashi, Mamoru, Tamura, Takashi, Esaki, Jiro, Miki, Shinji, Onodera, Tomoya, Mabuchi, Hiroshi, Furukawa, Yutaka, Tanaka, Masaru, Komiya, Tatsuhiko, Soga, Yoshiharu, Hanyu, Michiya, Ando, Kenji, Kadota, Kazushige, Minatoya, Kenji, Nakagawa, Yoshihisa, and Kimura, Takeshi

Abstract

AIMS: There is a scarcity of studies comparing percutaneous coronary intervention (PCI) using new-generation drug-eluting stents (DES) with coronary artery bypass grafting (CABG) in patients with multi-vessel coronary artery disease. METHODS AND RESULTS: The CREDO-Kyoto PCI/CABG registry Cohort-3 enrolled 14927 consecutive patients who underwent first coronary revascularization with PCI or isolated CABG between January 2011 and December 2013. The current study population consisted of 2464 patients who underwent multi-vessel coronary revascularization including revascularization of left anterior descending coronary artery (LAD) either with PCI using new-generation DES (N = 1565), or with CABG (N = 899). Patients in the PCI group were older and more often had severe frailty, but had less complex coronary anatomy, and less complete revascularization than those in the CABG group. Cumulative 5-year incidence of a composite of all-cause death, myocardial infarction or stroke was not significantly different between the 2 groups (25.0% versus 21.5%, P = 0.15). However, after adjusting confounders, the excess risk of PCI relative to CABG turned to be significant for the composite endpoint (HR 1.27, 95%CI 1.04-1.55, P = 0.02). PCI as compared with CABG was associated with comparable adjusted risk for all-cause death (HR 1.22, 95%CI 0.96-1.55, P = 0.11), and stroke (HR 1.17, 95%CI 0.79-1.73, P = 0.44), but with excess adjusted risk for myocardial infarction (HR 1.58, 95%CI 1.05-2.39, P = 0.03), and any coronary revascularization (HR 2.66, 95%CI 2.06-3.43, P<0.0001). CONCLUSIONS: In this observational study, PCI with new-generation DES as compared with CABG was associated with excess long-term risk for major cardiovascular events in patients who underwent multi-vessel coronary revascularization including LAD.

Published
2022

18. Modifiers of the Risk of Diabetes for Long-Term Outcomes After Coronary Revascularization

Author

Yamaji, Kyohei, primary, Shiomi, Hiroki, additional, Morimoto, Takeshi, additional, Matsumura-Nakano, Yukiko, additional, Ehara, Natsuhiko, additional, Sakamoto, Hiroki, additional, Takeji, Yasuaki, additional, Yoshikawa, Yusuke, additional, Yamamoto, Ko, additional, Kato, Eri T., additional, Imada, Kazuaki, additional, Tada, Takeshi, additional, Taniguchi, Ryoji, additional, Nishikawa, Ryusuke, additional, Tada, Tomohisa, additional, Uegaito, Takashi, additional, Ogawa, Tatsuya, additional, Yamada, Miho, additional, Takeda, Teruki, additional, Eizawa, Hiroshi, additional, Tamura, Nobushige, additional, Tambara, Keiichi, additional, Suwa, Satoru, additional, Shirotani, Manabu, additional, Tamura, Toshihiro, additional, Inoko, Moriaki, additional, Nishizawa, Junichiro, additional, Natsuaki, Masahiro, additional, Sakai, Hiroshi, additional, Yamamoto, Takashi, additional, Kanemitsu, Naoki, additional, Ohno, Nobuhisa, additional, Ishii, Katsuhisa, additional, Marui, Akira, additional, Tsuneyoshi, Hiroshi, additional, Terai, Yasuhiko, additional, Nakayama, Shogo, additional, Yamazaki, Kazuhiro, additional, Takahashi, Mamoru, additional, Tamura, Takashi, additional, Esaki, Jiro, additional, Miki, Shinji, additional, Onodera, Tomoya, additional, Mabuchi, Hiroshi, additional, Furukawa, Yutaka, additional, Tanaka, Masaru, additional, Komiya, Tatsuhiko, additional, Soga, Yoshiharu, additional, Hanyu, Michiya, additional, Domei, Takenori, additional, Ando, Kenji, additional, Kadota, Kazushige, additional, Minatoya, Kenji, additional, Nakagawa, Yoshihisa, additional, Kimura, Takeshi, additional, Matsuda, Mitsuo, additional, Takeuchi, Yuzo, additional, Mitsuoka, Hirokazu, additional, Konishi, Takashi, additional, Ootani, Seiji, additional, Fujiwara, Hisayoshi, additional, Takatsu, Yoshiki, additional, Sato, Yukihito, additional, Kataoka, Kazuaki, additional, Nohara, Ryuji, additional, Nakano, Kimisato, additional, Miyamoto, Syoichi, additional, Kunihiko, Nagai, additional, Murakami, Tomoyuki, additional, Ishida, Katsuya, additional, Nobuyoshi, Masakiyo, additional, Yamaji, Kyohei, additional, Yasumoto, Hitoshi, additional, Iwabuchi, Masashi, additional, Kato, Masayuki, additional, Tatami, Ryozo, additional, Hattori, Ryuichi, additional, Kita, Toru, additional, Kihara, Yasuki, additional, Kato, Hiroshi, additional, Aoyama, Takeshi, additional, Sakurai, Takahiro, additional, Kawanami, Masaki, additional, Suyama, Tamaki, additional, Tada, Eiji, additional, Inada, Tsukasa, additional, Uzui, Hiroyasu, additional, Nakano, Akira, additional, Lee, Jong-Dae, additional, Takizawa, Akinori, additional, Ryuzo, Nawada, additional, Shinoda, Eiji, additional, Takahashi, Masaaki, additional, Horie, Minoru, additional, Takashima, Hiroyuki, additional, Toyofuku, Mamoru, additional, Kotoura, Hajime, additional, Miura, Akira, additional, Matoba, Yoshiki, additional, Takumi, Takuro, additional, Tei, Chuwa, additional, Hamasaki, Shuichi, additional, Doi, Osamu, additional, Kambara, Hirofumi, additional, Kaburagi, Satoshi, additional, Mitsudo, Kazuaki, additional, Mizoguchi, Tetsu, additional, Akira, Yoshida, additional, Kaneda, Kazuhisa, additional, Ogawa, Hisao, additional, Sugamura, Koichi, additional, Sugiyama, Seigo, additional, Doyama, Kiyoshi, additional, Araki, Makoto, additional, Sakata, Ryuzo, additional, Ikeda, Tadashi, additional, Onoe, Masahiko, additional, Yamanaka, Kazuo, additional, Iwakura, Atsushi, additional, Fujiwara, Keiichi, additional, Soga, Kinji, additional, Matsushita, Tsutomu, additional, Nishiwaki, Noboru, additional, Yoshida, Yuichi, additional, Okada, Yukikatsu, additional, Nasu, Michihiro, additional, Koyama, Tadaaki, additional, Tanaka, Kuniyoshi, additional, Koshiji, Takaaki, additional, Morioka, Koichi, additional, Shimamoto, Mitsuomi, additional, Yamazaki, Fumio, additional, Aota, Masaki, additional, Hara, Hiroyuki, additional, Tabata, Takafumi, additional, Imoto, Yutaka, additional, Yamamoto, Hiroyuki, additional, Matsuda, Katsuhiko, additional, Nara, Masafumi, additional, Nakajima, Hiroyuki, additional, Kawasuji, Michio, additional, Moriyama, Syuji, additional, Arimura, Sakiko, additional, Fujino, Yumika, additional, Hanazawa, Miya, additional, Hibi, Chikako, additional, Kato, Risa, additional, Kinoshita, Yui, additional, Kitagawa, Kumiko, additional, Kitamura, Masayo, additional, Kuwahara, Takahiro, additional, Sachiko, Maeda, additional, Miki, Izumi, additional, Minematsu, Saeko, additional, Nishida, Satoko, additional, Okamoto, Naoko, additional, Saeki, Asuka, additional, Sasae, Hitomi, additional, Sato, Yuki, additional, Takahashi, Asuka, additional, Takinami, Emi, additional, Tezuka, Saori, additional, Tsuda, Marina, additional, Tsumori, Miyuki, additional, Uchida, Yuriko, additional, Yamamoto, Yuko, additional, Yamauchi, Misato, additional, Yamazaki, Itsuki, additional, Yoshimoto, Mai, additional, Abe, Mitsuru, additional, Fuki, Masayuki, additional, Hayano, Mamoru, additional, Kato, Eri, additional, Kato, Yoshihiro, additional, Nakajima, Tetsu, additional, Nakatsuma, Kenji, additional, Tazaki, Junichi, additional, Tokushige, Akihiro, additional, Watanabe, Hiroki, additional, Yaku, Hidenori, additional, Yamamoto, Erika, additional, and Yamashita, Yugo, additional

Published
2022
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20. Percutaneous coronary intervention using new-generation drug-eluting stents versus coronary arterial bypass grafting in stable patients with multi-vessel coronary artery disease: From the CREDO-Kyoto PCI/CABG registry Cohort-3

Author

Watanabe, Hiroki, Yamamoto, Ko, Shiomi, Hiroki, Morimoto, Takeshi, Kato, Eri, Matsumura, Yukiko, Nakatsuma, Kenji, Takeji, Yasuaki, Yaku, Hidenori, Yamamoto, Erika, Yamashita, Yugo, Yoshikawa, Yusuke, Fuki, Masayuki, Yamaji, Kyohei, Ehara, Natsuhiko, Sakamoto, Hiroki, Imada, Kazuaki, Tada, Takeshi, Taniguchi, Ryoji, Nishikawa, Ryusuke, Tada, Tomohisa, Uegaito, Takashi, Ogawa, Tatsuya, Yamada, Miho, Takeda, Teruki, Eizawa, Hiroshi, Tamura, Nobushige, Tambara, Keiichi, Suwa, Satoru, Shirotani, Manabu, Tamura, Toshihiro, Inoko, Moriaki, Nishizawa, Junichiro, Natsuaki, Masahiro, Sakai, Hiroshi, Yamamoto, Takashi, Kanemitsu, Naoki, Ohno, Nobuhisa, Ishii, Katsuhisa, Marui, Akira, Tsuneyoshi, Hiroshi, Terai, Yasuhiko, Nakayama, Shogo, Yamazaki, Kazuhiro, Takahashi, Mamoru, Tamura, Takashi, Esaki, Jiro, Miki, Shinji, Onodera, Tomoya, Mabuchi, Hiroshi, Furukawa, Yutaka, Tanaka, Masaru, Komiya, Tatsuhiko, Soga, Yoshiharu, Hanyu, Michiya, Ando, Kenji, Kadota, Kazushige, Minatoya, Kenji, Nakagawa, Yoshihisa, and Kimura, Takeshi

Subjects
Ischemic stroke, Multidisciplinary, Revascularization, Coronary angioplasty, Coronary artery bypass grafting, Drug-Eluting Stents, Coronary Artery Disease, Coronary revascularization, Cardiovascular disease risk, Stroke, Myocardial infarction, Percutaneous Coronary Intervention, Humans, Registries, Coronary Artery Bypass, Coronary stenting
Abstract

Aims There is a scarcity of studies comparing percutaneous coronary intervention (PCI) using new-generation drug-eluting stents (DES) with coronary artery bypass grafting (CABG) in patients with multi-vessel coronary artery disease. Methods and results The CREDO-Kyoto PCI/CABG registry Cohort-3 enrolled 14927 consecutive patients who underwent first coronary revascularization with PCI or isolated CABG between January 2011 and December 2013. The current study population consisted of 2464 patients who underwent multi-vessel coronary revascularization including revascularization of left anterior descending coronary artery (LAD) either with PCI using new-generation DES (N = 1565), or with CABG (N = 899). Patients in the PCI group were older and more often had severe frailty, but had less complex coronary anatomy, and less complete revascularization than those in the CABG group. Cumulative 5-year incidence of a composite of all-cause death, myocardial infarction or stroke was not significantly different between the 2 groups (25.0% versus 21.5%, P = 0.15). However, after adjusting confounders, the excess risk of PCI relative to CABG turned to be significant for the composite endpoint (HR 1.27, 95%CI 1.04–1.55, P = 0.02). PCI as compared with CABG was associated with comparable adjusted risk for all-cause death (HR 1.22, 95%CI 0.96–1.55, P = 0.11), and stroke (HR 1.17, 95%CI 0.79–1.73, P = 0.44), but with excess adjusted risk for myocardial infarction (HR 1.58, 95%CI 1.05–2.39, P = 0.03), and any coronary revascularization (HR 2.66, 95%CI 2.06–3.43, P Conclusions In this observational study, PCI with new-generation DES as compared with CABG was associated with excess long-term risk for major cardiovascular events in patients who underwent multi-vessel coronary revascularization including LAD.

Published
2022
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24. Intermediate-term outcomes of aortic valve replacement with bioprosthetic or mechanical valves in patients on hemodialysis

Author

Nakatsu, Taro, primary, Minakata, Kenji, additional, Tanaka, Shiro, additional, Minatoya, Kenji, additional, Nishizawa, Junichiro, additional, Ohno, Nobuhisa, additional, Esaki, Jiro, additional, Ueyama, Koji, additional, Koyama, Tadaaki, additional, Hanyu, Michiya, additional, Tamura, Nobushige, additional, Komiya, Tatsuhiko, additional, Saito, Yuhei, additional, Kanemitsu, Naoki, additional, Soga, Yoshiharu, additional, Shiraga, Kotaro, additional, Nakayama, Shogo, additional, Nonaka, Michihito, additional, Sakaguchi, Genichi, additional, Nishimura, Kazunobu, additional, and Yamanaka, Kazuo, additional

Published
2019
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26. Impact of concomitant tricuspid regurgitation on long-term outcomes in severe aortic stenosis

Author

Amano, Masashi, primary, Izumi, Chisato, additional, Taniguchi, Tomohiko, additional, Morimoto, Takeshi, additional, Miyake, Makoto, additional, Nishimura, Shunsuke, additional, Kitai, Takeshi, additional, Kato, Takao, additional, Kadota, Kazushige, additional, Ando, Kenji, additional, Furukawa, Yutaka, additional, Inada, Tsukasa, additional, Inoko, Moriaki, additional, Ishii, Katsuhisa, additional, Sakaguchi, Genichi, additional, Yamazaki, Fumio, additional, Koyama, Tadaaki, additional, Komiya, Tatsuhiko, additional, Yamanaka, Kazuo, additional, Nishiwaki, Noboru, additional, Kanemitsu, Naoki, additional, Saga, Toshihiko, additional, Ogawa, Tatsuya, additional, Nakayama, Shogo, additional, Tsuneyoshi, Hiroshi, additional, Iwakura, Atsushi, additional, Shiraga, Kotaro, additional, Hanyu, Michiya, additional, Ohno, Nobuhisa, additional, Fukumoto, Atsushi, additional, Yamada, Tomoyuki, additional, Nishizawa, Junichiro, additional, Esaki, Jiro, additional, Minatoya, Kenji, additional, Nakagawa, Yoshihisa, additional, and Kimura, Takeshi, additional

Published
2018
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33. New therapeutic approach for impaired arteriogenesis in diabetic mouse hindlimb ischemia

Author

Bir, Shyarnal Chandra, Fujita, Masatoshi, Marui, Akira, Hirose, Keiiehi, Arai, Yoshio, Sakaguchi, Hisashi, Huang, Yuhong, Esaki, Jiro, Ikeda, Tadashi, Tabata, Yasuhiko, Komeda, Masashi, Bir, Shyarnal Chandra, Fujita, Masatoshi, Marui, Akira, Hirose, Keiiehi, Arai, Yoshio, Sakaguchi, Hisashi, Huang, Yuhong, Esaki, Jiro, Ikeda, Tadashi, Tabata, Yasuhiko, and Komeda, Masashi

Published
2008

34. New therapeutic approach for impaired arteriogenesis in diabetic mouse hindlimb ischemia

Author

40281092, 50211371, Bir, Shyarnal Chandra, Fujita, Masatoshi, Marui, Akira, Hirose, Keiiehi, Arai, Yoshio, Sakaguchi, Hisashi, Huang, Yuhong, Esaki, Jiro, Ikeda, Tadashi, Tabata, Yasuhiko, Komeda, Masashi, 40281092, 50211371, Bir, Shyarnal Chandra, Fujita, Masatoshi, Marui, Akira, Hirose, Keiiehi, Arai, Yoshio, Sakaguchi, Hisashi, Huang, Yuhong, Esaki, Jiro, Ikeda, Tadashi, Tabata, Yasuhiko, and Komeda, Masashi

Published
2008

35. Sustained release of prostaglandin E1 potentiates the impaired therapeutic angiogenesis by basic fibroblast growth factor in diabetic murine Hindlimb ischemia

Author

40281092, 50211371, Huang, Yuhong, Marui, Akira, Sakaguchi, Hisashi, Esaki, Jiro, Arai, Yoshio, Hirose, Keiichi, Bir, Shyamal Chandra, Horiuchi, Hisanori, Maruyama, Takayuki, Ikeda, Tadashi, Tabata, Yasuhiko, Komeda, Masashi, 40281092, 50211371, Huang, Yuhong, Marui, Akira, Sakaguchi, Hisashi, Esaki, Jiro, Arai, Yoshio, Hirose, Keiichi, Bir, Shyamal Chandra, Horiuchi, Hisanori, Maruyama, Takayuki, Ikeda, Tadashi, Tabata, Yasuhiko, and Komeda, Masashi

Published
2008

36. Less-invasive and highly effective method for preventing methicillin-resistant Staphylococcus aureus graft infection by local sustained release of vancomycin

Author

50211371, 40281092, Sakaguchi, Hisashi, Marui, Akira, Hirose, Keiichi, Nomura, Takamasa, Arai, Yoshio, Bir, Shyamal Chandra, Huang, Yuhong, Esaki, Jiro, Tabata, Yasuhiko, Ikeda, Tadashi, Komeda, Masashi, 50211371, 40281092, Sakaguchi, Hisashi, Marui, Akira, Hirose, Keiichi, Nomura, Takamasa, Arai, Yoshio, Bir, Shyamal Chandra, Huang, Yuhong, Esaki, Jiro, Tabata, Yasuhiko, Ikeda, Tadashi, and Komeda, Masashi

Published
2008

41. Sustained Release of Prostaglandin E1 Potentiates the Impaired Therapeutic Angiogenesis by Basic Fibroblast Growth Factor in Diabetic Murine Hindlimb Ischemia

Author

Huang, Yuhong, primary, Marui, Akira, additional, Sakaguchi, Hisashi, additional, Esaki, Jiro, additional, Arai, Yoshio, additional, Hirose, Keiichi, additional, Bir, Shyamal Chandra, additional, Horiuchi, Hisanori, additional, Maruyama, Takayuki, additional, Ikeda, Tadashi, additional, Tabata, Yasuhiko, additional, and Komeda, Masashi, additional

Published
2008
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47. Impact of concomitant tricuspid regurgitation on long-term outcomes in severe aortic stenosis.

Author

Amano M, Izumi C, Taniguchi T, Morimoto T, Miyake M, Nishimura S, Kitai T, Kato T, Kadota K, Ando K, Furukawa Y, Inada T, Inoko M, Ishii K, Sakaguchi G, Yamazaki F, Koyama T, Komiya T, Yamanaka K, Nishiwaki N, Kanemitsu N, Saga T, Ogawa T, Nakayama S, Tsuneyoshi H, Iwakura A, Shiraga K, Hanyu M, Ohno N, Fukumoto A, Yamada T, Nishizawa J, Esaki J, Minatoya K, Nakagawa Y, and Kimura T

Subjects
Aged, Aged, 80 and over, Aortic Valve Stenosis physiopathology, Cohort Studies, Comorbidity, Conservative Treatment methods, Echocardiography, Doppler methods, Female, Humans, Logistic Models, Male, Multivariate Analysis, Prognosis, Proportional Hazards Models, Registries, Retrospective Studies, Risk Assessment, Severity of Illness Index, Survival Analysis, Treatment Outcome, Tricuspid Valve Insufficiency physiopathology, Aortic Valve Stenosis diagnostic imaging, Aortic Valve Stenosis epidemiology, Heart Valve Prosthesis Implantation methods, Tricuspid Valve Insufficiency diagnostic imaging, Tricuspid Valve Insufficiency epidemiology
Abstract

Aims: Tricuspid regurgitation (TR) has been reported to be associated with worse survival in various heart diseases, but there are few data in aortic stenosis (AS)., Methods and Results: In the Contemporary Outcomes after Surgery and Medical Treatment in Patients with Severe Aortic Stenosis (CURRENT AS) Registry enrolling 3815 consecutive patients with severe AS, there were 628 patients with moderate or severe TR (TR group) and 3187 patients with no or mild TR (no TR group). The study patients were subdivided into the initial aortic valve replacement (AVR) stratum (n = 1197) and the conservative stratum (n = 2618) according to treatment strategy. The primary outcome measure was a composite of aortic valve-related death or hospitalization due to heart failure. The 5-year freedom rate from the primary outcome measure was significantly lower in the TR group than in the no TR group (49.1% vs. 67.3%, P < 0.001). Even after adjusting for confounders, the excess risk of TR relative to no TR for the primary outcome measure remained significant [hazard ratio (HR): 1.25, 95% confidence interval (CI): 1.06-1.48; P = 0.008]. The trend for the excess adjusted risk in the TR group was consistent in the initial AVR and the conservative strata (HR 1.55, 95% CI: 0.97-2.48; P = 0.07; HR 1.22, 95% CI: 1.02-1.46; P = 0.03, respectively). In the initial AVR stratum, the 5-year freedom rate from the primary outcome measure was not different between the two groups with (n = 56) or without (n = 91) concomitant tricuspid annuloplasty (61.5% vs. 72.1%, P = 0.48)., Conclusion: The presence of clinically significant TR concomitant with severe AS is associated with a poor long-term outcome, regardless of the initial treatment strategy., (Published on behalf of the European Society of Cardiology. All rights reserved. © The Author(s) 2018. For permissions, please email: journals.permissions@oup.com.)

Published
2019
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48. Early Surgery vs. Surgery After Watchful Waiting for Asymptomatic Severe Aortic Stenosis.

Author

Miyake M, Izumi C, Taniguchi T, Morimoto T, Amano M, Nishimura S, Kitai T, Kato T, Kadota K, Ando K, Furukawa Y, Inada T, Inoko M, Ishii K, Sakaguchi G, Yamazaki F, Koyama T, Komiya T, Yamanaka K, Nishiwaki N, Kanemitsu N, Saga T, Ogawa T, Nakayama S, Tsuneyoshi H, Iwakura A, Shiraga K, Hanyu M, Ohno N, Fukumoto A, Yamada T, Nishizawa J, Esaki J, Minatoya K, Nakagawa Y, and Kimura T

Subjects
Aged, Aortic Valve surgery, Aortic Valve Stenosis mortality, Female, Heart Valve Prosthesis Implantation mortality, Humans, Male, Middle Aged, Survival Rate, Time Factors, Time-to-Treatment, Aortic Valve Stenosis surgery, Heart Valve Prosthesis Implantation methods, Watchful Waiting
Abstract

Background: There is no large-scale study comparing postoperative mortality after aortic valve replacement (AVR) for asymptomatic severe aortic stenosis (AS) between initial treatment with AVR vs. eventual AVR after conservative management., Methods and results: We analyzed data from a multicenter registry enrolling 3,815 consecutive patients with severe AS. Of 1,808 asymptomatic patients, 286 patients initially underwent AVR (initial AVR group), and 377 patients were initially managed conservatively and eventually underwent AVR (AVR after watchful waiting group). Mortality after AVR was compared between the 2 groups. Subgroup analysis according to peak aortic jet velocity (Vmax) at diagnosis was also conducted. There was no significant difference between the 2 groups in 5-year overall survival (OS; 86.0% vs. 84.1%, P=0.34) or cardiovascular death-free survival (DFS; 91.3% vs. 91.1%, P=0.61), but on subgroup analysis of patients with Vmax ≥4.5 m/s at diagnosis, the initial AVR group was superior to the AVR after watchful waiting group in both 5-year OS (88.4% vs. 70.6%, P=0.003) and cardiovascular DFS (91.9% vs. 81.7%, P=0.023)., Conclusions: Asymptomatic severe AS patients who underwent AVR after watchful waiting had a postoperative survival rate similar to those who initially underwent AVR. In a subgroup of patients with Vmax ≥4.5 m/s at diagnosis, however, the AVR after watchful waiting group had worse postoperative survival rate than the initial AVR group.

Published
2018
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49. New therapeutic approach for impaired arteriogenesis in diabetic mouse hindlimb ischemia.

Author

Bir SC, Fujita M, Marui A, Hirose K, Arai Y, Sakaguchi H, Huang Y, Esaki J, Ikeda T, Tabata Y, and Komeda M

Subjects
Animals, Base Sequence, DNA Primers genetics, Delayed-Action Preparations, Diabetes Mellitus, Experimental genetics, Diabetes Mellitus, Experimental pathology, Diabetic Angiopathies drug therapy, Diabetic Angiopathies genetics, Diabetic Angiopathies pathology, Fibroblast Growth Factor 2 administration & dosage, Gene Expression, Hindlimb blood supply, Ischemia complications, Ischemia genetics, Ischemia pathology, Male, Mice, Mice, Inbred C57BL, Receptor, Serotonin, 5-HT2A genetics, Serotonin Antagonists administration & dosage, Succinates administration & dosage, Collateral Circulation drug effects, Diabetes Mellitus, Experimental drug therapy, Ischemia drug therapy, Neovascularization, Physiologic drug effects
Abstract

Background: The combined treatment of sustained-release basic fibroblast growth factor (Sr-bFGF) and a 5-hydroxytryptamine(2A) blocker, sarpogrelate, was evaluated to see whether it reversed the impaired collateral circulation in diabetic (DM) mouse hindlimb ischemia., Method and Results: Diabetic and normal mice with ischemic hindlimb were randomly assigned to 1 of 5 experimental groups (no treatment, sarpogrelate 50 mg . kg(-1) . day(-1), 20 microg or 50 microg Sr-bFGF and a combined treatment of 20 microg Sr-bFGF and sarpogrelate), and treated for 4 weeks. Tissue blood perfusion (TBP), vascular density (angiogenesis) and the number of mature vessels (arteriogenesis) were checked by the use of standard methods. Although angiogenesis was comparable (161+/-14 vs 154+/-12 vessels/mm(2)), the laser Doppler perfusion image index (LDPII) (0.43+/-0.11 (SD) vs 0.63+/-0.08, p<0.05) and arteriogenesis (8+/-3 vs 12+/-4 vessels/mm(2), p<0.05) were significantly lower in DM mice than those in normal mice. The dose of Sr-bFGF for the sufficient number of mature vessels (>or=45 vessels/mm(2)) and LDPII (>or=0.9) was 20 microg for the normal mice, and 50 microg for the DM mice, which was reduced with the aid of sarpogrelate. Conclusions A combined therapy of Sr-bFGF and sarpogrelate is effective for neovascularization to reverse the impaired arteriogenesis and TBP in DM mice.

Published
2008
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