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1. Contact-force local impedance algorithm to guide effective pulmonary vein isolation in AF patients: 1-year outcome from an international multicenter clinical setting

Author

Solimene, Franscesco, Maggio, Ruggero, De Sanctis, Valerio, Escande, William, Malacrida, Maurizio, Stabile, Giuseppe, Zakine, Cyril, Champ-Rigot, Laure, Anselmino, Matteo, Ferraro, Anna, Mantica, Massimo, Zucchelli, Giulio, Dell’Era, Gabriele, Mascia, Giuseppe, Ricci Maga, Renata, Pandozi, Claudio, Rossi, Pietro, Scaglione, Marco, Zingarini, Gianluca, Garnier, Fabien, Loricchio, Maria Luisa, Pelargonio, Gemma, and Lepillier, Antoine

Published
2024
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2. Malignant Purkinje ectopy induced by sodium channel blockers

Author

Escande, William, Gourraud, Jean-Baptiste, Haissaguerre, Michel, Gandjbakhch, Estelle, Lavergne, Thomas, Martins, Raphael, Cheniti, Ghassen, Krisai, Philipp, Hermida, Jean Sylvain, Maury, Philippe, Merino, Jose-Louis, Pasquié, Jean-Luc, Combes, Nicolas, Surget, Elodie, Duchateau, Josselin, Pambrun, Thomas, Derval, Nicolas, Hocini, Mélèze, Jaïs, Pierre, Postema, Pieter G., Nademanee, Koonlawee, Vigmond, Ed, Bernus, Olivier, Sacher, Frederic, and Probst, Vincent

Published
2022
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4. Are wall thickness channels defined by computed tomography predictive of isthmuses of postinfarction ventricular tachycardia?

Author

Takigawa, Masateru, Duchateau, Josselin, Sacher, Frederic, Martin, Ruairidh, Vlachos, Konstantinos, Kitamura, Takeshi, Sermesant, Maxime, Cedilnik, Nicolas, Cheniti, Ghassen, Frontera, Antonio, Thompson, Nathaniel, Martin, Calire, Massoullie, Gregoire, Bourier, Felix, Lam, Anna, Wolf, Michael, Escande, William, André, Clémentine, Pambrun, Thomas, Denis, Arnaud, Derval, Nicolas, Hocini, Meleze, Haissaguerre, Michel, Cochet, Hubert, and Jaïs, Pierre

Published
2019
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5. Insights from atrial surface activation throughout atrial tachycardia cycle length: A new mapping tool

Author

Takigawa, Masateru, Martin, Claire A., Derval, Nicolas, Denis, Arnaud, Vlachos, Konstantinos, Kitamura, Takeshi, Frontera, Antonio, Martin, Ruairidh, Cheniti, Ghassen, Lam, Anna, Bourier, Felix, Thompson, Nathaniel, Wolf, Michael, Massoulié, Grégoire, Escande, William, Andre, Clementine, Zeng, Li Jun, Nakatani, Yosuke, Roux, Jean-Rodolphe, Duchateau, Josselin, Pambrun, Thomas, Sacher, Frederic, Cochet, Hubert, Hocini, Meleze, Haissaguerre, Michel, and Jais, Pierre

Published
2019
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6. The role of Marshall bundle epicardial connections in atrial tachycardias after atrial fibrillation ablation

Author

Vlachos, Konstantinos, Denis, Arnaud, Takigawa, Masateru, Kitamura, Takeshi, Martin, Claire A., Frontera, Antonio, Martin, Ruairidh, Bazoukis, George, Bourier, Felix, Cheniti, Ghassen, Duchateau, Josselin, Thompson, Nathaniel, Massoullie, Gregoire, Lam, Anna, Wolf, Michael, Escande, William, Klotz, Nicolas, Pambrun, Thomas, Sacher, Frederic, Hocini, Meleze, Haissaguerre, Michel, Jais, Pierre, and Derval, Nicolas

Published
2019
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8. Mechanism of Recurrence of Atrial Tachycardia: Comparison Between First Versus Redo Procedures in a High-Resolution Mapping System

Author

Takigawa, Masateru, Derval, Nicolas, Martin, Claire A., Vlachos, Konstantinos, Denis, Arnaud, Nakatani, Yosuke, Kitamura, Takeshi, Cheniti, Ghassen, Bourier, Felix, Lam, Anna, Martin, Ruairidh, Frontera, Antonio, Thompson, Nathaniel, Massoullié, Grégoire, Wolf, Michael, Escande, William, André, Clémentine, Zeng, Li-jun, Roux, Jean-Rodolphe, Duchateau, Josselin, Pambrun, Thomas, Sacher, Frederic, Cochet, Hubert, Hocini, Mélèze, Haïssaguerre, Michel, and Jaïs, Pierre

Published
2020
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9. PO-02-070 COMBINED LOCAL IMPEDANCE AND CONTACT FORCE FOR SUCCESSFUL RADIOFREQUENCY ABLATION OF ATRIAL FIBRILLATION

Author

Stabile, Giuseppe, primary, Lepillier, Antoine, additional, Anselmino, Matteo, additional, Maggio, Ruggero, additional, DeSanctis, Valerio, additional, ZAKINE, Cyril, additional, RIGOT, Laure CHAMP, additional, Dell'Era, Gabriele, additional, Garnier, Fabien, additional, Mascia, Giuseppe, additional, Segreti, Luca, additional, Escande, William, additional, Cosaro, Giuseppe, additional, Malacrida, Maurizio, additional, Maglia, Giampiero, additional, and Solimene, Francesco, additional

Published
2023
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11. Predictors of Advanced His-Purkinje Conduction Disturbances in Patients With Unexplained Syncope and Bundle Branch Block

Author

Boulé, Stéphane, Ouadah, Aïcha, Langlois, Carole, Botcherby, Edward J., Verbrugge, Eric, Huchette, David, Salleron, Julia, Mostefa Kara, Meriem, Kouakam, Claude, Brigadeau, François, Klug, Didier, Marquié, Christelle, Guédon-Moreau, Laurence, Wissocque, Ludivine, Escande, William, Lacroix, Dominique, and Kacet, Salem

Published
2014
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14. Malignant Purkinje ectopy induced by sodium channel blockers

Author

Escande, William, Gourraud, Jean-Baptiste, Haissaguerre, Michel, Gandjbakhch, Estelle, Lavergne, Thomas, Martins, Raphael, Cheniti, Ghassen, Krisai, Philipp, Hermida, Jean Sylvain, Maury, Philippe, Merino, Jose-Louis, Pasquié, Jean-Luc, Combes, Nicolas, Surget, Elodie, Duchateau, Josselin, Pambrun, Thomas, Derval, Nicolas, Hocini, M. lèze, Jaïs, Pierre, Postema, Pieter G., Nademanee, Koonlawee, Vigmond, Ed, Bernus, Olivier, Sacher, Frederic, Probst, Vincent, IHU-LIRYC, Université Bordeaux Segalen - Bordeaux 2-CHU Bordeaux [Bordeaux], Institut du Thorax [Nantes], Centre de recherche Cardio-Thoracique de Bordeaux [Bordeaux] (CRCTB), Université Bordeaux Segalen - Bordeaux 2-CHU Bordeaux [Bordeaux]-Institut National de la Santé et de la Recherche Médicale (INSERM), CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Research Unit on Cardiovascular and Metabolic Diseases (ICAN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Institut de Cardiométabolisme et Nutrition = Institute of Cardiometabolism and Nutrition [CHU Pitié Salpêtrière] (IHU ICAN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-CHU Pitié-Salpêtrière [AP-HP], Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), CHU Pontchaillou [Rennes], Laboratoire Traitement du Signal et de l'Image (LTSI), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM), Mécanismes physiopathologiques et conséquences des calcifications vasculaires - UR UPJV 7517 (MP3CV), Université de Picardie Jules Verne (UPJV)-CHU Amiens-Picardie, Physiologie & médecine expérimentale du Cœur et des Muscles [U 1046] (PhyMedExp), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Cardiology, and ACS - Heart failure & arrhythmias

Subjects
Adult, Male, Ajmaline, Flecainide, Idiopathic ventricular fibrillation, Reproducibility of Results, Middle Aged, Purkinje system, Ventricular Premature Complexes, Electrocardiography, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, Physiology (medical), Catheter Ablation, Tachycardia, Ventricular, Humans, [SDV.IB]Life Sciences [q-bio]/Bioengineering, Cardiology and Cardiovascular Medicine, Premature ventricular complex, Sodium Channel Blockers
Abstract

International audience; Background: Sodium channel blocker (SCB) infusion is used to unmask the electrocardiographic pattern of Brugada syndrome. The test may also induce premature ventricular complexes (PVCs) in individuals without Brugada pattern, the clinical relevance of which is little known.Objective: The purpose of this study was to describe the prevalence of short-coupled (Sc) PVCs induced by ajmaline or flecainide in patients with suspected or documented severe ventricular arrhythmias.Methods: We reviewed the SCB tests performed in 335 patients with suspected ventricular arrhythmias and structurally normal hearts in 9 centers. ScPVCs were defined as frequent and repetitive PVCs with an R-on-T pattern on SCB tests. Repeated SCB tests were performed in 7 patients and electrophysiological mapping of ScPVCs in 9.Results: Sixteen patients (8 men; mean age 36 ± 11 years) showed ScPVCs and were included. ScPVCs appeared 229 ± 118 seconds after the initiation of infusion and displayed coupling intervals of 288 ± 28 ms. ScPVC patterns were monomorphic in 12 patients, originating from the Purkinje system in mapped patients. Repetitive PVCs were induced in 15 patients (94%) including polymorphic ventricular tachycardias in 9 (56%). SCB infusion was repeated 45 (interquartile range 0.6-46) months later and induced identical ScPVC in all. SCB test was the only mean to reveal the malignant arrhythmia in 6 patients. Catheter ablation was performed in 9 patients, resulting in arrhythmia elimination in 8 with a follow-up of 6 (interquartile range 2-9) years.Conclusion: SCB can induce ScPVC, mostly from Purkinje tissue, in a small subset of patients with idiopathic ventricular arrhythmias. Its high reproducibility suggests a distinct individual mechanism.

Published
2021
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16. Acute and mid-term outcome of ethanol infusion of vein of Marshall for the treatment of perimitral flutter

Author

Takigawa, Masateru, primary, Vlachos, Konstantinos, additional, Martin, Claire A, additional, Bourier, Felix, additional, Denis, Arnaud, additional, Kitamura, Takeshi, additional, Cheniti, Ghassen, additional, Lam, Anna, additional, Martin, Ruairidh, additional, Frontera, Antonio, additional, Thompson, Nathaniel, additional, Massoullié, Grégoire, additional, Wolf, Michael, additional, Escande, William, additional, André, Clémentine, additional, Zeng, Li-Jun, additional, Nakatani, Yosuke, additional, Nakashima, Takashi, additional, Pillois, Xavier, additional, Ramirez, Daniel, additional, Duchateau, Josselin, additional, Pambrun, Thomas, additional, Sacher, Frederic, additional, Cochet, Hubert, additional, Hocini, Mélèze, additional, Haïssaguerre, Michel, additional, Jaïs, Pierre, additional, and Derval, Nicolas, additional

Published
2020
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17. Relationship of Preexisting Cardiovascular Comorbidities to Newly Diagnosed Atrial Fibrillation After Ischemic Stroke

Author

Escande, William, Boveda, Serge, Defaye, Pascal, Leclercq, Christophe, Sadoul, Nicolas, Perier, Marie-Cecile, Deharo, Jean-Claude, Fauchier, Laurent, Marijon, Eloi, Piot, Olivier, Bisson, Arnaud, Clementy, Nicolas, Bodin, Alexandre, Angoulvant, Denis, Babuty, Dominique, Lip, Gregory Y.H., IHU-LIRYC, Université Bordeaux Segalen - Bordeaux 2-CHU Bordeaux [Bordeaux], Clinique Pasteur [Toulouse], Cardiac Stimulation and Rhythmology, CHU Grenoble, Laboratoire des Écoulements Géophysiques et Industriels [Grenoble] (LEGI ), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Laboratoire d'Electronique des Systèmes TEmps Réel (LESTER), Université de Bretagne Sud (UBS)-Centre National de la Recherche Scientifique (CNRS), Paris-Centre de Recherche Cardiovasculaire (PARCC - UMR-S U970), Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Dysoxie, suractivité : aspects cellulaires et intégratifs thérapeutiques (DS-ACI / UMR MD2), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Département de Cardiologie [Hôpital de la Timone - APHM], Assistance Publique - Hôpitaux de Marseille (APHM)- Hôpital de la Timone [CHU - APHM] (TIMONE), Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), Éducation Éthique Santé EA 7505 (EES), Université de Tours (UT), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), Centre cardiologique du Nord (CCN), CHU Trousseau [Tours], CHU Trousseau [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Cellules Dendritiques, Immunomodulation et Greffes, Service de Cardiologie B, University of Liverpool, and Aalborg University [Denmark] (AAU)

Subjects
Male, medicine.medical_specialty, Heart disease, Comorbidity, Newly diagnosed, 030204 cardiovascular system & hematology, [SHS]Humanities and Social Sciences, Brain Ischemia, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, Internal medicine, Atrial Fibrillation, medicine, Humans, Longitudinal Studies, Stroke, Aged, Aged, 80 and over, Advanced and Specialized Nursing, Entire population, Preexisting Condition Coverage, business.industry, Incidence (epidemiology), Atrial fibrillation, Middle Aged, medicine.disease, Confidence interval, Cardiovascular Diseases, Ischemic stroke, Cardiology, Female, France, Neurology (clinical), Cardiology and Cardiovascular Medicine, business, 030217 neurology & neurosurgery, Follow-Up Studies
Abstract

Background and Purpose— There remains uncertainty as whether newly diagnosed atrial fibrillation (AF) after ischemic stroke reflects underlying heart disease and represents an increased risk of cardioembolic stroke, or whether it is triggered by neurogenic mechanisms. We aimed to determine whether cardiovascular comorbidities in patients with new AF after ischemic stroke differ from patients with previous known AF or without AF. Methods— This French longitudinal cohort study was based on the database covering hospital care from 2009 to 2012 for the entire population. Results— Of 336 291 patients with ischemic stroke, 240 459 (71.5%) had no AF and 95 832 (28.5%) had previously known AF at baseline. Patients without previous AF had a mean CHA 2 DS 2 -VASc score of 4.98±1.63 SD. During a mean follow-up of 7.9±11.5 months, 14 095 (5.9%) of these patients had incident AF, representing an annual incidence of AF after ischemic stroke of 8.9 per 100 person-years (95% confidence interval, 8.8–9.0). New AF patients had higher CHA 2 DS 2 -VASc score, more likely comorbidities, and more frequent history of previous transient ischemic attack than patients with previous known AF or without AF. Conclusions— Preexisting cardiovascular comorbidities underlie AF newly diagnosed after stroke. Consequently, these high-risk patients should be closely monitored for incident AF to facilitate an earlier diagnosis of AF and avoid stroke with appropriate thromboprophylaxis.

Published
2017
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21. 0372: Outcomes of patients with unexplained syncope, bundle branch block and normal electrophysiological study

Author

Mostefa Kara, Meriem, primary, Boule, Stéphane, additional, Verbrugge, Eric, additional, Huchette, David, additional, Langlois, Carole, additional, Salleron, Julia, additional, Ouadah, Aicha, additional, Botcherby, Edward, additional, Kouakam, Claude, additional, Brigadeau, François, additional, Lacroix, Dominique, additional, Klug, Didier, additional, Marquie, Christelle, additional, Guedon, Laurence, additional, Achere, Charles, additional, Wissocque, Ludivine, additional, Meurice, Jonathan, additional, Escande, William, additional, and Kacet, Salem, additional

Published
2015
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23. Acute and mid-term outcome of ethanol infusion of vein of Marshall for the treatment of perimitral flutter.

Author

Takigawa M, Vlachos K, Martin CA, Bourier F, Denis A, Kitamura T, Cheniti G, Lam A, Martin R, Frontera A, Thompson N, Massoullié G, Wolf M, Escande W, André C, Zeng LJ, Nakatani Y, Nakashima T, Pillois X, Ramirez D, Duchateau J, Pambrun T, Sacher F, Cochet H, Hocini M, Haïssaguerre M, Jaïs P, and Derval N

Subjects
Ethanol, Humans, Treatment Outcome, Atrial Fibrillation surgery, Atrial Flutter diagnosis, Atrial Flutter drug therapy, Atrial Flutter surgery, Brain Ischemia, Catheter Ablation, Stroke
Abstract

Aims: We hypothesized that an epicardial approach using ethanol infusion in the vein of Marshall (EIVOM) may improve the result of ablation for perimitral flutter (PMF)., Methods and Results: We studied 103 consecutive patients with PMF undergoing high-resolution mapping. The first 71 were treated with radiofrequency (RF) ablation alone (RF-group), and the next 32 underwent EIVOM followed by RF on the endocardial and epicardial mitral isthmus (EIVOM/RF-group). Contact force was not measured during ablation. Acute and 1-year outcomes were compared. Flutter termination rates were similar between the RF-group (63/71, 88.7%) and EIVOM/RF-group (31/32, 96.8%, P = 0.27). Atrial tachycardia (AT) terminated with EIVOM alone in 22/32 (68.6%) in the EIVOM/RF-group. Bidirectional block of mitral isthmus was always achieved in the EIVOM/RF-group, but significantly less frequently achieved in the RF-group (62/71, 87.3%; P = 0.05). Median RF duration for AT termination/conversion was shorter [0 (0-6) s in the EIVOM/RF-group than 312 (55-610) s in the RF-group, P < 0.0001], as well as for mitral isthmus block in the EIVOM/RF-group [246 (0-663) s] than in the RF-group [900 (525-1310) s, P < 0.0001]. Pericardial effusion was observed in 1/32 (3.2%) in EIVOM/RF-group and 5/71 (7.0%) in RF-group (P = 0.66); two in RF-group required drainage and one of them developed subsequent ischaemic stroke. One-year follow-up demonstrated fewer recurrences in the EIVOM/RF-group [6/32 (18.8%)] than in the RF-group [29/71 (40.8%), P = 0.04]. By multivariate analysis, only EIVOM was significantly associated with less AT recurrence (hazard ratio = 0.35, P = 0.018)., Conclusion: Ethanol infusion in the vein of Marshall may reduce RF duration required for PMF termination as well as for mitral isthmus block without severe complications, and the mid-term outcome may be improved by this approach., (Published on behalf of the European Society of Cardiology. All rights reserved. © The Author(s) 2020. For permissions, please email: journals.permissions@oup.com.)

Published
2020
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24. The double adenosine test: a simple and non-invasive tip to unmask unapparent pre-excitations: an example of Mahaim fibres.

Author

Boulé S, Escande W, and Lamblin N

Subjects
Action Potentials, Adolescent, Diagnostic Errors, Heart Rate, Humans, Pre-Excitation, Mahaim-Type physiopathology, Predictive Value of Tests, Reproducibility of Results, Accessory Atrioventricular Bundle, Adenosine administration & dosage, Electrocardiography, Pre-Excitation, Mahaim-Type diagnosis, Purinergic P1 Receptor Agonists administration & dosage
Published
2017
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