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275 results on '"Eshak, Ehab S"'

15. Plasma levels of n-3 fatty acids and risk of coronary heart disease among Japanese: The Japan Public Health Center-based (JPHC) study

Author

Tsugane, S., Sawada, N., Iwasaki, M., Sasazuki, S., Yamaji, T., Shimazu, T., Goto, A., Hidaka, A., Hanaoka, T., Ogata, J., Baba, S., Mannami, T., Okayama, A., Kokubo, Y., Miyakawa, K., Saito, F., Koizumi, A., Sano, Y., Hashimoto, I., Ikuta, T., Tanaba, Y., Sato, H., Roppongi, Y., Takashima, T., Suzuki, H., Miyajima, Y., Suzuki, N., Nagasawa, S., Furusugi, Y., Nagai, N., Ito, Y., Komatsu, S., Minamizono, T., Sanada, H., Hatayama, Y., Kobayashi, F., Uchino, H., Shirai, Y., Kondo, T., Sasaki, R., Watanabe, Y., Miyagawa, Y., Kobayashi, Y., Machida, M., Kobayashi, K., Tsukada, M., Kishimoto, Y., Takara, E., Fukuyama, T., Kinjo, M., Irei, M., Sakiyama, H., Imoto, K., Yazawa, H., Seo, T., Seiko, A., Ito, F., Shoji, F., Saito, R., Murata, A., Minato, K., Motegi, K., Fujieda, T., Yamato, S., Doi, M., Matsui, K., Abe, T., Katagiri, M., Suzuki, M., Terao, A., Ishikawa, Y., Tagami, T., Sueta, H., Doi, H., Urata, M., Okamoto, N., Ide, F., Goto, H., Fujita, R., Sou, Y., Onga, N., Takaesu, H., Uehara, M., Nakasone, T., Yamakawa, M., Horii, F., Asano, I., Yamaguchi, H., Aoki, K., Maruyama, S., Ichii, M., Takano, M., Tsubono, Y., Suzuki, K., Honda, Y., Yamagishi, K., Sakurai, S., Tsuchiya, N., Kabuto, M., Yamaguchi, M., Matsumura, Y., Sasaki, S., Watanabe, S., Akabane, M., Kadowaki, T., Inoue, M., Noda, M., Mizoue, T., Kawaguchi, Y., Takashima, Y., Yoshida, Y., Nakamura, K., Takachi, R., Ishihara, J., Matsushima, S., Natsukawa, S., Shimizu, H., Sugimura, H., Tominaga, S., Hamajima, N., Iso, H., Sobue, T., Iida, M., Ajiki, W., Ioka, A., Sato, S., Maruyama, E., Konishi, M., Okada, K., Saito, I., Yasuda, N., Kono, S., Akiba, S., Isobe, T., Sato, Y., Hamazaki, Kei, Iso, Hiroyasu, Eshak, Ehab S., Ikehara, Satoyo, Ikeda, Ai, Iwasaki, Motoki, Hamazaki, Tomohito, and Tsugane, Shoichiro

Published
2018
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30. Associations of different isomeric forms of serum lycopene with cardiovascular-disease and all-cause mortality

Author

Zhang, Yanan, primary, Zhai, Xiaobing, additional, Chai, Honglin, additional, Liu, Keyang, additional, Ma, Wenzhi, additional, Li, Shiyang, additional, Zeng, Jing, additional, Yang, Mei, additional, Zhou, Feng, additional, Zheng, Surui, additional, Wu, Xia, additional, Xiang, Bing, additional, Cao, Jinhong, additional, Eshak, Ehab S., additional, and Jiang, Can, additional

Published
2023
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31. Associations of eicosapentaenoic acid and docosahexaenoic acid intakes with cardiovascular and all-cause mortality in patients with diabetes: Result from National Health and Nutrition Examination Survey 1999–2008

Author

Huang, Nian, primary, Wang, Fang, additional, Li, Shiyang, additional, Zhai, Xiaobing, additional, Ma, Wenzhi, additional, Liu, Keyang, additional, Sheerah, Haytham A., additional, Cao, Jinhong, additional, and Eshak, Ehab S., additional

Published
2023
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36. Relationship between Endothelial Dysfunction and Prevalence of Chronic Kidney Disease : The Circulatory Risk in Communities Study (CIRCS)

Author

Li, Yuting, Cui, Renzhe, Liu, Keyang, Eshak, Ehab S., Cui, Meishan, Dong, Jiayi, Imano, Hironori, Muraki, Isao, Kiyama, Masahiko, Kitamura, Akihiko, Okada, Takeo, YAMAGISHI, Kazumasa, Umesawa, Mitsumasa, Ohira, Tetsuya, Iso, Hiroyasu, and CIRCS investigators

Abstract

Aims: Patients with chronic kidney disease (CKD) have a higher burden of cardiovascular morbidity and mortality than the general population. Endothelial dysfunction has been suggested to play a role in both glomerular filtration rate loss and cardiovascular damage. Thus, the present study aimed to evaluate the relationship between endothelial dysfunction and the prevalence of CKD in the general Japanese population. Methods: We conducted a cross-sectional study of 1042 men and women aged 30–81 years in two communities under the Circulatory Risk in Communities Study between 2013 and 2017. Endothelial function was evaluated by percent change of brachial artery flow-mediated dilation (%FMD) before and after the cuff inflation. Results: Among the total 1042 participants, there were 62 cases of CKD (~6%). The multivariable odds ratios (ORs) (95% confidence intervals [CIs]) of CKD according to quartiles of %FMD were 2.02 (0.68–5.99), 3.56 (1.27–9.94), and 3.14 (1.10–8.93) for the third to lowest quartile compared with the highest %FMD quartile; p for trend=0.02. The respective multivariable ORs (95% CIs) of CKD in subjects without antihypertensive medication use (39 cases among 886 subjects) were 1.83 (0.46–7.33), 3.41 (0.92–12.61), and 4.60 (1.22–17.31); p for trend=0.01, and that for one-point decrement in %FMD was 1.16 (1.00–1.35); p for interaction with the status of antihypertensive medication use was 0.12. Conclusions: Our cross-sectional study suggested the relationship between endothelial dysfunction and the higher prevalence of CKD in the general Japanese population.

Published
2021

42. Manganese intake from foods and beverages is associated with a reduced risk of type 2 diabetes

Author

YAMAGISHI, Kazumasa, Eshak, Ehab S., Muraki, Isao, Imano, Hironori, Tamakoshi, Akiko, and Iso, Hiroyasu

Abstract

Background Despite the hypoglycemic and antioxidant effects of manganese, only one recent Chinese study has investigated the association between dietary manganese intake and type 2 diabetes. Methods We recruited 19,862 Japanese men and women in the Japan Collaborative Cohort Study. The participants completed a food frequency questionnaire at the baseline survey (1988 = 1990) and a diabetes history at both baseline and 5-year surveys. We calculated the odds ratios (95 % CIs) of the 5-year cumulative incidence of self-reported physician-diagnosed type 2 diabetes according to quartiles of dietary manganese intake. Results Within the 5-year period, we confirmed 530 new cases of type 2 diabetes (263 in men and 267 in women) with a 5-year cumulative incidence of 2.7 % (3.6 % in men and 2.1 % in women). Higher manganese intake was inversely associated with the women’s but not the men’s cumulative risk of type 2 diabetes over the 5-year period. In a full model adjusted for the participants’ characteristics, diabetes risk factors and a wide range of dietary variables, the multivariable odds ratios (95 %CIs) of type 2 diabetes across the increasing quartiles of manganese intake (Q1 to Q4) were 1.00, 0.97 (0.65, 1.43), 1.04 (0.67, 1.61) and 1.10 (0.64, 1.92), p-trend = 0.66 among men and 1.00, 0.74 (0.51, 1.06), 0.62 (0.41, 0.94) and 0.53 (0.31, 0.88), p-trend = 0.01 among women. The association was observed mainly for those with low iron intake in women, particularly premenopausal women. Conclusion Strong inverse associations between dietary manganese intake and risk of type 2 diabetes were observed in women but not men.

Published
2021

45. Association between dietary intake of n‐3 polyunsaturated fatty acids and risk of colorectal cancer in the Japanese population: The Japan Collaborative Cohort Study.

Author

Kato, Ayako, Okada, Chika, Eshak, Ehab S., Iso, Hiroyasu, and Tamakoshi, Akiko

Subjects
OMEGA-3 fatty acids, UNSATURATED fatty acids, COLORECTAL cancer, FOOD consumption, JAPANESE people
Abstract

Background: Epidemiological studies of the dietary intake of specific n‐3 polyunsaturated fatty acids (PUFA) and anatomical subsite‐specific colorectal cancer (CRC) are limited. We examined the prospective associations of total n‐3 PUFA, marine‐derived n‐3 PUFA [combined eicosapentaenoic acid (EPA), docosapentaenoic acid (DPA), and docosahexaenoic acid (DHA)], and alpha‐linolenic acid (ALA) as plant‐derived n‐3 PUFA with the risk of CRC by subsite in the Japan Collaborative Cohort Study. Methods: The participants completed a self‐administered food frequency questionnaire and had no prior history of CRC. Cox proportional hazards model was used to determine the associations between n‐3 PUFAs intake and CRC risk overall and by anatomical subsite. Results: During the median 13.8‐year follow‐up period, 699 of the 42,536 participants aged 40–79 years developed incident CRC. An inverse association was found between dietary ALA intake and the risk of distal colon cancer; the multivariable hazard ratios and 95% confidence intervals for the highest quartiles (Q4) were 0.41 (0.21–0.81; p trend = 0.01) compared with the lowest quartiles (Q1). Marine n‐3 PUFA intake was not associated with CRC risk in the overall or anatomical subsite‐specific analyses. Conclusion: Our findings suggest that higher ALA intake may be beneficial for lowering the risk of distal colon cancer. [ABSTRACT FROM AUTHOR]

Published
2023
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46. Association of Beta-2 Microglobulin with Stroke and All-Cause Mortality in Adults Aged =40 in U.S.: NHANES III.

Author

Yanan Zhang, Xiaobing Zhai, Keyang Liu, Wenzhi Ma, Shiyang Li, Jing Zeng, Mei Yang, Feng Zhou, Bing Xiang, Jinhong Cao, and Eshak, Ehab S.

Abstract

Background: Stroke is the predominant cause of death worldwide. We aimed to investigate the association of serum beta-2 microglobulin (ß2M) concentrations with risk of stroke and all-cause mortalities in a cohort study. Methods: Overall, 4914 U.S. adults (mean age = 63.0 years, 44.3% male) were recruited from the National Health and Nutrition Examination Survey (NHANES 1). During a median follow-up of 19.4 years, 254 stroke deaths and 3415 all-cause deaths were identified by the National Center for Health Statistics. The associations of ß2M with stroke and all-cause mortalities were investigated by using weighted Cox proportional hazard regression models. Results: ß2M was positively associated with stroke and all-cause mortality in unadjusted models and multivariable-adjusted models. The multivariable HR (95% CI) for stroke mortality in Q5 VS Q1 of serum ß2M concentrations was 3.45 (1.33-8.91; p for trend = 0.001) and that for all-cause mortality was 3.95 (3.05-5.12; p for trend < 0.001). In subgroup analyses, the association of ß2M and stroke mortality did not vary by different levels of sociodemographic and general stroke risk factors (p interaction > 0.05). In addition, the magnitude of positive association between ß2M with all-cause mortality did vary by age, ratio of family income to poverty, smoking status, and history of hypertensive (p interaction < 0.05). Conclusions: Our findings suggest that support that ß2M may be a marker of stroke and all-cause mortality, which provides a new perspective for the study of cerebrovascular health and long-term survival in the future. [ABSTRACT FROM AUTHOR]

Published
2023
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