1. [The assessment of urinary nicotine metabolites concentration in children and teenagers with oesophagitis].
- Author
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Wielkoszyński T, Kalita B, Paluch M, Opara M, Pluszczyk M, Obuchowicz A, Wilczyński M, Slimok M, and Sikora A
- Subjects
- Adolescent, Biomarkers blood, Biomarkers urine, Child, Comorbidity, Cotinine blood, Environmental Monitoring, Epidemiological Monitoring, Esophagitis blood, Esophagitis epidemiology, Gastroesophageal Reflux blood, Gastroesophageal Reflux epidemiology, Gastroesophageal Reflux urine, Helicobacter Infections blood, Helicobacter Infections epidemiology, Humans, Nicotine blood, Poland epidemiology, Smoking blood, Smoking epidemiology, Cotinine urine, Esophagitis urine, Helicobacter Infections urine, Nicotine urine, Smoking urine, Tobacco Smoke Pollution analysis
- Abstract
Tobacco smoke is important pathogenetic agent of stomach digestive and duodenum ulcers, oesophagitis as well as gastro-oesophageal reflux disease. The aim of work was the assessment of urinary nicotine metabolites concentration in children and teenagers diagnosed and treated in Paediatrics Chair of Medical University of Silesia by chronic stomach pains, or oesophagitis and gastrooesophageal reflux disease symptoms. Urine was sampled from 54 persons before gastrofiberoscopy, in which the main nicotine metabolites concentration was determined by ELISA method and given per creatinine concentration. It was shown, that 30% of examined population was intensively exposed to tobacco smoke (actively or passively smoking), but 37% passively exposed to nicotine. Significant higher nicotine metabolites concentration was stated in the currently H. pylori infected sick, however without differences of these biomarkers concentrations between group with oesophagis in endoscopy as well as histopathologic examination and group without these features.
- Published
- 2006