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Background Advanced hepatocellular carcinoma (HCC) is commonly diagnosed using non-invasive radiological criteria (NIRC) defined by the European Association for the Study of the Liver or the American Association for the Study of Liver Diseases. In 2017, The National Institute for Clinical Excellence mandated histological confirmation of disease to authorise the use of sorafenib in the UK. Methods This was a prospective multicentre audit in which patients suitable for sorafenib were identified at multidisciplinary meetings. The primary analysis cohort (PAC) was defined by the presence of Child-Pugh class A liver disease and performance status 0–2. Clinical, radiological and histological data were reported locally and collected on a standardised case report form. Results Eleven centres reported 418 cases, of which 361 comprised the PAC. Overall, 76% had chronic liver disease and 66% were cirrhotic. The diagnostic imaging was computed tomography in 71%, magnetic resonance imaging in 27% and 2% had both. Pre-existing histology was available in 45 patients and 270 underwent a new biopsy, which confirmed HCC in 93.4%. Alternative histological diagnoses included cholangiocarcinoma (CC) and combined HCC-CC. In cirrhotic patients, NIRC criteria had a sensitivity of 65.4% and a positive predictive value of 91.4% to detect HCC. Two patients (0.7%) experienced mild post-biopsy bleeding. Conclusion The diagnostic biopsy is safe and feasible for most patients eligible for systemic therapy

Background: Large hepatic artery aneurysms are rare, especially spontaneous ones without history of hepatopancreatobiliary surgery or trauma. They are serious and need attention due to risk of spontaneous rupture. Management depends on local expertise with endovascular management being the preferred option, and surgical repair usually reserved to ruptured aneurysms in hemodynamically unstable patients. Methods: A 54-year-old female patient was referred to our hospital for treatment of incidentally discovered large hepatic artery aneurysm without obvious etiology. The decision was made to attempt percutaneous endovascular management at the interventional radiology unit. Result: The aneurysm sac was successfully excluded using covered stents. This was complicated by right hepatic artery occlusion and clinically insignificant contrast extravasation. These complications did not have any clinical sequel in terms of hemodynamic stability or impaired liver function. The patient was safely discharged few days after the procedure. Conclusion: Endovascular management of spontaneous large hepatic artery aneurysms is effective. Potential complications include hepatic artery occlusion and dissection, which may or may not have serious clinical consequences. This offers a less invasive treatment option compared to surgery.

The Eysenck Personality Questionnaire (EPQ) was administered to three groups of male, Saudi, drug addicts treated at Al-Amal Hospital, Jeddah. Each group consisted of 50 patients. The three groups were: volunteer in-patients (VIP), volunteer out-patients (VOP) and involuntary in-patients (IIP). The IIP group scored significantly higher than the VIP and VOP groups on the P scale (P

The purposes of this study can be summarized in defining the improvement of customer service, and inventory control as a result of installing an automated system in Kastero market in terms of efficiency, effectiveness, benefits, and usefulness of services provided by this system. The key findings of the study is that the service provided to the customers of Kastero market, and the inventory control process at Kastero market as a result of installing the automated system is improved to a medium degree, and it is also preferable to the customers to a medium degree. Most recommended to Kastero market to install the automated system, and continuously update, and improve the efficiency, and effectiveness of this automated system which will help to improve customer service, and inventory control as proposed.