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2. Strategies for Membrane Protein Analysis by Mass Spectrometry

Author

Prados-Rosales, Rafael C., Aragoneses-Cazorla, Guillermo, Estevez, Hector, Garcia-Calvo, Estefania, Machuca, Andres, Luque-Garcia, Jose L., Crusio, Wim E., Series Editor, Lambris, John D., Series Editor, Rezaei, Nima, Series Editor, Woods, Alisa G., editor, and Darie, Costel C., editor

Published
2019
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9. Characterization of protective extracellular membrane-derived vesicles produced by Streptococcus pneumoniae

Author

Olaya-Abril, Alfonso, Prados-Rosales, Rafael, McConnell, Michael J., Martín-Peña, Reyes, González-Reyes, José Antonio, Jiménez-Munguía, Irene, Gómez-Gascón, Lidia, Fernández, Javier, Luque-García, José L., García-Lidón, Carlos, Estévez, Héctor, Pachón, Jerónimo, Obando, Ignacio, Casadevall, Arturo, Pirofski, Liise-anne, and Rodríguez-Ortega, Manuel J.

Published
2014
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10. Short‐chain fatty acids during pregnancy in multiple sclerosis: A prospective cohort study

Author

Cuello, Juan Pablo, primary, Martínez Ginés, María Luisa, additional, García Domínguez, José Manuel, additional, Tejeda‐Velarde, Amalia, additional, Lozano Ros, Alberto, additional, Higueras, Yolanda, additional, Meldaña Rivera, Ariana, additional, Goicochea Briceño, Haydee, additional, Garcia‐Tizon, Santiago, additional, de León‐Luis, Juan, additional, Medina Heras, Silvia, additional, Fernández Velasco, José Ignacio, additional, Pérez‐Pérez, Silvia, additional, García‐Martínez, María Ángel, additional, Pardo‐Rodríguez, Beatriz, additional, Domínguez‐Mozo, María Inmaculada, additional, García‐Calvo, Estefanía, additional, Estévez, Héctor, additional, Luque‐García, Jose Luis, additional, Villar, Luisa Maria, additional, and Alvarez‐Lafuente, Roberto, additional

Published
2021
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11. Short‐chain fatty acids during pregnancy in multiple sclerosis: A prospective cohort study.

Author

Cuello, Juan Pablo, Martínez Ginés, María Luisa, García Domínguez, José Manuel, Tejeda‐Velarde, Amalia, Lozano Ros, Alberto, Higueras, Yolanda, Meldaña Rivera, Ariana, Goicochea Briceño, Haydee, Garcia‐Tizon, Santiago, de León‐Luis, Juan, Medina Heras, Silvia, Fernández Velasco, José Ignacio, Pérez‐Pérez, Silvia, García‐Martínez, María Ángel, Pardo‐Rodríguez, Beatriz, Domínguez‐Mozo, María Inmaculada, García‐Calvo, Estefanía, Estévez, Héctor, Luque‐García, Jose Luis, and Villar, Luisa Maria

Subjects
SHORT-chain fatty acids, MULTIPLE sclerosis, LIQUID chromatography-mass spectrometry, LONGITUDINAL method, COHORT analysis, PUERPERAL disorders
Abstract

Background and purpose: Short‐chain fatty acids (SCFAs) can have pro‐ or anti‐inflammatory properties, but their relationship with multiple sclerosis (MS) relapses during pregnancy remains unknown. This study aimed to explore SCFA profiles in MS patients during pregnancy and to assess their association with the appearance of relapses during pregnancy and postpartum. Methods: We prospectively included 53 pregnant MS patients and 21 healthy control women. Patients were evaluated during pregnancy and puerperium. SCFAs were measured by liquid chromatography–mass spectrometry. Results: Sixteen patients (32%) had relapses during pregnancy or puerperium, and 37 (68%) did not. All MS patients showed significant increases in acetate levels during pregnancy and the postpartum period compared to non‐MS women. However, propionate and butyrate values were associated with disease activity. Their values were higher in nonrelapsing patients and remained similar to the control group in relapsing patients. The variable that best identified active patients was the propionate/acetate ratio. Ratios of <0.36 during the first trimester were associated with higher inflammatory activity (odds ratio = 165, 95% confidence interval = 10.2–239.4, p < 0.01). Most nonrelapsing patients showed values of >0.36, which were similar to those in healthy pregnant women. Conclusions: Low propionate/acetate ratio values during the first trimester of gestation identified MS patients at risk of relapses during pregnancy and the postpartum period. [ABSTRACT FROM AUTHOR]

Published
2022
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12. Acetate correlates with disability and immune response in multiple sclerosis

Author

Pérez-Pérez, Silvia, primary, Domínguez-Mozo, María Inmaculada, additional, Alonso-Gómez, Aitana, additional, Medina, Silvia, additional, Villarrubia, Noelia, additional, Fernández-Velasco, Jose Ignacio, additional, García-Martínez, María Ángel, additional, García-Calvo, Estefanía, additional, Estévez, Héctor, additional, Costa-Frossard, Lucienne, additional, Alvarez-Cermeño, Jose C., additional, Luque-Garcia, Jose L., additional, Arroyo, Rafael, additional, Villar, Luisa M., additional, and Alvarez-Lafuente, Roberto, additional

Published
2020
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16. Apuntes sobre el debate académico en Colombia en el proceso de reconocimiento gubernamental de la creación como práctica de generación de nuevo conocimiento, desarrollo tecnológico e innovación.

Author

Bonilla Estévez, Héctor Antonio, Cabanzo, Francisco, Delgado, Tania Catalina, Hernández Salgar, Oscar Andrés, Niño Soto, Alexander Stward, and Salamanca, Juan

Abstract

Copyright of Cuadernos de Música, Artes Visuales y Artes Escénicas is the property of Pontificia Universidad Javeriana and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2018
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17. PFOS exposure disrupts the regulation of prolactin secretion by amino acids

Author

Lafuente Anunciacion, Fernández-Pérez Belén, Moyano Rosario, and Estévez Héctor

Subjects
chemistry.chemical_classification, medicine.medical_specialty, Endocrinology, chemistry, Biochemistry, Internal medicine, medicine, Secretion, General Medicine, Toxicology, Prolactin, Amino acid
Published
2012

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