Search

Reports that eosinophils and neutrophils from the blood of infected mice resistant to reinfection were tested for their ability to adhere to the different parasitic larval stages of the murine nematode parasite Nematospiroides dubius. Indication that N. dubius may undergo a series of antigenic changes during its life cycle; Conclusion that antibodies capable of mediating a granulocyte attachment are elicited predominantly against the early tissue developmental forms of the parasite.

Reports on the activation of complement via the alternative pathway by the cuticular surface of the infectious third-stage larvae of Nematospiroides dubius. Promotion of the adherence of mouse peritoneal exudates cells to the larval cubicle during incubation in vitro by the sensitization of larvae with complement or with antibodies from the serum of immune mice; Reduction of the infectivity of larvae sensitized with antibody or complement after incubation with cells from immune mice.

Examines the mechanisms of immunity in nude mice to an infection with Nematospiroides dubius. Reasons behind the susceptibility of nude mice to Nematospiroides infection; Full complement of T cells needed to develop maximum resistance against the infective third-stage larvae.